Result of FASTA (omim) for
pFN21AB0150
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0150, 1464 aa
1>>>pF1KB0150 1464 - 1464 aa - 1464 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.7382+/-0.00049; mu= -12.2649+/- 0.030
mean_var=367.9923+/-78.720, 0's: 0 Z-trim(118.8): 101 B-trim: 1595 in 1/53
Lambda= 0.066858
statistics sampled from 32082 (32187) to 32082 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.377), width: 16
Scan time: 16.230
The best scores are: opt bits E(85289)
NP_001308636 (OMIM: 601993) nuclear receptor coact (1464) 9845 965.1 0
NP_001308632 (OMIM: 601993) nuclear receptor coact (1464) 9845 965.1 0
NP_006531 (OMIM: 601993) nuclear receptor coactiva (1464) 9845 965.1 0
NP_001308642 (OMIM: 601993) nuclear receptor coact (1310) 8843 868.4 0
XP_016868452 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0
XP_016868454 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0
XP_016868453 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0
XP_016868456 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0
XP_016868455 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0
XP_016868460 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0
XP_016868459 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0
XP_016868458 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0
XP_016868451 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0
XP_016868450 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0
XP_016868457 (OMIM: 601993) PREDICTED: nuclear rec (1533) 8824 866.6 0
XP_016868461 (OMIM: 601993) PREDICTED: nuclear rec (1379) 7822 770.0 0
NP_001308640 (OMIM: 601993) nuclear receptor coact (1395) 5802 575.1 1.3e-162
NP_001308641 (OMIM: 601993) nuclear receptor coact (1395) 5802 575.1 1.3e-162
XP_016868462 (OMIM: 601993) PREDICTED: nuclear rec ( 799) 5304 527.0 2.3e-148
NP_001167559 (OMIM: 601937) nuclear receptor coact (1415) 2566 263.0 1.2e-68
NP_001167558 (OMIM: 601937) nuclear receptor coact (1423) 2531 259.6 1.2e-67
NP_006525 (OMIM: 601937) nuclear receptor coactiva (1420) 2524 258.9 2e-67
NP_858045 (OMIM: 601937) nuclear receptor coactiva (1424) 2517 258.3 3.2e-67
XP_016860657 (OMIM: 602691) PREDICTED: nuclear rec (1399) 1996 208.0 4.2e-52
XP_016860658 (OMIM: 602691) PREDICTED: nuclear rec (1399) 1996 208.0 4.2e-52
XP_005264685 (OMIM: 602691) PREDICTED: nuclear rec (1399) 1996 208.0 4.2e-52
NP_671756 (OMIM: 602691) nuclear receptor coactiva (1399) 1996 208.0 4.2e-52
XP_005264683 (OMIM: 602691) PREDICTED: nuclear rec (1440) 1996 208.0 4.3e-52
NP_671766 (OMIM: 602691) nuclear receptor coactiva (1440) 1996 208.0 4.3e-52
XP_005264682 (OMIM: 602691) PREDICTED: nuclear rec (1441) 1996 208.0 4.3e-52
NP_003734 (OMIM: 602691) nuclear receptor coactiva (1441) 1996 208.0 4.3e-52
>>NP_001308636 (OMIM: 601993) nuclear receptor coactivat (1464 aa)
initn: 9845 init1: 9845 opt: 9845 Z-score: 5147.7 bits: 965.1 E(85289): 0
Smith-Waterman score: 9845; 99.9% identity (100.0% similar) in 1464 aa overlap (1-1464:1-1464)
10 20 30 40 50 60
pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
NP_001 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG
1390 1400 1410 1420 1430 1440
1450 1460
pF1KB0 NLFPNQLPGMDMIKQEGDTTRKYC
::::::::::::::::::::::::
NP_001 NLFPNQLPGMDMIKQEGDTTRKYC
1450 1460
>>NP_001308632 (OMIM: 601993) nuclear receptor coactivat (1464 aa)
initn: 9845 init1: 9845 opt: 9845 Z-score: 5147.7 bits: 965.1 E(85289): 0
Smith-Waterman score: 9845; 99.9% identity (100.0% similar) in 1464 aa overlap (1-1464:1-1464)
10 20 30 40 50 60
pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
NP_001 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG
1390 1400 1410 1420 1430 1440
1450 1460
pF1KB0 NLFPNQLPGMDMIKQEGDTTRKYC
::::::::::::::::::::::::
NP_001 NLFPNQLPGMDMIKQEGDTTRKYC
1450 1460
>>NP_006531 (OMIM: 601993) nuclear receptor coactivator (1464 aa)
initn: 9845 init1: 9845 opt: 9845 Z-score: 5147.7 bits: 965.1 E(85289): 0
Smith-Waterman score: 9845; 99.9% identity (100.0% similar) in 1464 aa overlap (1-1464:1-1464)
10 20 30 40 50 60
pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
NP_006 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG
1390 1400 1410 1420 1430 1440
1450 1460
pF1KB0 NLFPNQLPGMDMIKQEGDTTRKYC
::::::::::::::::::::::::
NP_006 NLFPNQLPGMDMIKQEGDTTRKYC
1450 1460
>>NP_001308642 (OMIM: 601993) nuclear receptor coactivat (1310 aa)
initn: 8843 init1: 8843 opt: 8843 Z-score: 4626.1 bits: 868.4 E(85289): 0
Smith-Waterman score: 8843; 99.9% identity (100.0% similar) in 1310 aa overlap (155-1464:1-1310)
130 140 150 160 170 180
pF1KB0 GFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSIVNGG
::::::::::::::::::::::::::::::
NP_001 MNKSVYSILHVGDHTEFVKNLLPKSIVNGG
10 20 30
190 200 210 220 230 240
pF1KB0 SWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKEEGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKEEGED
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB0 LQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLVRRCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLVRRCI
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB0 QKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQTTNEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQTTNEP
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB0 QLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLSSNIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLSSNIN
220 230 240 250 260 270
430 440 450 460 470 480
pF1KB0 FPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPGQPTS
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPGQPTS
280 290 300 310 320 330
490 500 510 520 530 540
pF1KB0 MLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQALSEGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQALSEGH
340 350 360 370 380 390
550 560 570 580 590 600
pF1KB0 GVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQAESSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQAESSC
400 410 420 430 440 450
610 620 630 640 650 660
pF1KB0 HPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASSLSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASSLSDT
460 470 480 490 500 510
670 680 690 700 710 720
pF1KB0 NKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESSSTAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESSSTAP
520 530 540 550 560 570
730 740 750 760 770 780
pF1KB0 GSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTKLIAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTKLIAM
580 590 600 610 620 630
790 800 810 820 830 840
pF1KB0 KTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAIINDLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAIINDLM
640 650 660 670 680 690
850 860 870 880 890 900
pF1KB0 QLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAGPFPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAGPFPP
700 710 720 730 740 750
910 920 930 940 950 960
pF1KB0 IRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSAVRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSAVRVT
760 770 780 790 800 810
970 980 990 1000 1010 1020
pF1KB0 CAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGGPQYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGGPQYS
820 830 840 850 860 870
1030 1040 1050 1060 1070 1080
pF1KB0 QQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALLDQLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALLDQLY
880 890 900 910 920 930
1090 1100 1110 1120 1130 1140
pF1KB0 LALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQAQMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQAQMA
940 950 960 970 980 990
1150 1160 1170 1180 1190 1200
pF1KB0 QGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQQNRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQQNRQ
1000 1010 1020 1030 1040 1050
1210 1220 1230 1240 1250 1260
pF1KB0 PLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQRTLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQRTLM
1060 1070 1080 1090 1100 1110
1270 1280 1290 1300 1310 1320
pF1KB0 MRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATTPQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATTPQSP
1120 1130 1140 1150 1160 1170
1330 1340 1350 1360 1370 1380
pF1KB0 LMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQANTSMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQANTSMY
1180 1190 1200 1210 1220 1230
1390 1400 1410 1420 1430 1440
pF1KB0 SNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGGNLFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGGNLFP
1240 1250 1260 1270 1280 1290
1450 1460
pF1KB0 NQLPGMDMIKQEGDTTRKYC
::::::::::::::::::::
NP_001 NQLPGMDMIKQEGDTTRKYC
1300 1310
>>XP_016868452 (OMIM: 601993) PREDICTED: nuclear recepto (1533 aa)
initn: 8849 init1: 8801 opt: 8824 Z-score: 4615.2 bits: 866.6 E(85289): 0
Smith-Waterman score: 9430; 95.3% identity (95.4% similar) in 1496 aa overlap (1-1427:1-1496)
10 20 30 40 50 60
pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
XP_016 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300
pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYG--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGTGLRSPPPFTSPFS
1270 1280 1290 1300 1310 1320
1310
pF1KB0 -------------------------------------------------------ISQQP
:::::
XP_016 PVSPSVGSQLLSHSSLHGSQMNLANQGMIGNLGGQLGPVRSPQVQHSTFQALSSGISQQP
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KB0 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KB0 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ
1450 1460 1470 1480 1490 1500
1440 1450 1460
pF1KB0 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC
XP_016 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC
1510 1520 1530
>>XP_016868454 (OMIM: 601993) PREDICTED: nuclear recepto (1533 aa)
initn: 8849 init1: 8801 opt: 8824 Z-score: 4615.2 bits: 866.6 E(85289): 0
Smith-Waterman score: 9430; 95.3% identity (95.4% similar) in 1496 aa overlap (1-1427:1-1496)
10 20 30 40 50 60
pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
XP_016 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300
pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYG--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGTGLRSPPPFTSPFS
1270 1280 1290 1300 1310 1320
1310
pF1KB0 -------------------------------------------------------ISQQP
:::::
XP_016 PVSPSVGSQLLSHSSLHGSQMNLANQGMIGNLGGQLGPVRSPQVQHSTFQALSSGISQQP
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KB0 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KB0 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ
1450 1460 1470 1480 1490 1500
1440 1450 1460
pF1KB0 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC
XP_016 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC
1510 1520 1530
>>XP_016868453 (OMIM: 601993) PREDICTED: nuclear recepto (1533 aa)
initn: 8849 init1: 8801 opt: 8824 Z-score: 4615.2 bits: 866.6 E(85289): 0
Smith-Waterman score: 9430; 95.3% identity (95.4% similar) in 1496 aa overlap (1-1427:1-1496)
10 20 30 40 50 60
pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
XP_016 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300
pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYG--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGTGLRSPPPFTSPFS
1270 1280 1290 1300 1310 1320
1310
pF1KB0 -------------------------------------------------------ISQQP
:::::
XP_016 PVSPSVGSQLLSHSSLHGSQMNLANQGMIGNLGGQLGPVRSPQVQHSTFQALSSGISQQP
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KB0 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KB0 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ
1450 1460 1470 1480 1490 1500
1440 1450 1460
pF1KB0 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC
XP_016 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC
1510 1520 1530
>>XP_016868456 (OMIM: 601993) PREDICTED: nuclear recepto (1533 aa)
initn: 8849 init1: 8801 opt: 8824 Z-score: 4615.2 bits: 866.6 E(85289): 0
Smith-Waterman score: 9430; 95.3% identity (95.4% similar) in 1496 aa overlap (1-1427:1-1496)
10 20 30 40 50 60
pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
XP_016 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300
pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYG--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGTGLRSPPPFTSPFS
1270 1280 1290 1300 1310 1320
1310
pF1KB0 -------------------------------------------------------ISQQP
:::::
XP_016 PVSPSVGSQLLSHSSLHGSQMNLANQGMIGNLGGQLGPVRSPQVQHSTFQALSSGISQQP
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KB0 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KB0 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ
1450 1460 1470 1480 1490 1500
1440 1450 1460
pF1KB0 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC
XP_016 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC
1510 1520 1530
>>XP_016868455 (OMIM: 601993) PREDICTED: nuclear recepto (1533 aa)
initn: 8849 init1: 8801 opt: 8824 Z-score: 4615.2 bits: 866.6 E(85289): 0
Smith-Waterman score: 9430; 95.3% identity (95.4% similar) in 1496 aa overlap (1-1427:1-1496)
10 20 30 40 50 60
pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
XP_016 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300
pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYG--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGTGLRSPPPFTSPFS
1270 1280 1290 1300 1310 1320
1310
pF1KB0 -------------------------------------------------------ISQQP
:::::
XP_016 PVSPSVGSQLLSHSSLHGSQMNLANQGMIGNLGGQLGPVRSPQVQHSTFQALSSGISQQP
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KB0 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KB0 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ
1450 1460 1470 1480 1490 1500
1440 1450 1460
pF1KB0 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC
XP_016 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC
1510 1520 1530
>>XP_016868460 (OMIM: 601993) PREDICTED: nuclear recepto (1533 aa)
initn: 8849 init1: 8801 opt: 8824 Z-score: 4615.2 bits: 866.6 E(85289): 0
Smith-Waterman score: 9430; 95.3% identity (95.4% similar) in 1496 aa overlap (1-1427:1-1496)
10 20 30 40 50 60
pF1KB0 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 SNINFPINGPKEQMGMPIGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
XP_016 SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300
pF1KB0 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYG--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGTGLRSPPPFTSPFS
1270 1280 1290 1300 1310 1320
1310
pF1KB0 -------------------------------------------------------ISQQP
:::::
XP_016 PVSPSVGSQLLSHSSLHGSQMNLANQGMIGNLGGQLGPVRSPQVQHSTFQALSSGISQQP
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KB0 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQS
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KB0 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQ
1450 1460 1470 1480 1490 1500
1440 1450 1460
pF1KB0 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC
XP_016 VNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC
1510 1520 1530
1464 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 11:40:07 2016 done: Thu Nov 3 11:40:09 2016
Total Scan time: 16.230 Total Display time: 0.860
Function used was FASTA [36.3.4 Apr, 2011]