Result of FASTA (omim) for
pFN21AA0594
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0594, 1101 aa
1>>>pF1KA0594 1101 - 1101 aa - 1101 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.8626+/-0.000645; mu= -3.9390+/- 0.040
mean_var=368.5288+/-77.120, 0's: 0 Z-trim(115.2): 204 B-trim: 139 in 1/52
Lambda= 0.066810
statistics sampled from 25379 (25583) to 25379 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.3), width: 16
Scan time: 15.650
The best scores are: opt bits E(85289)
NP_055925 (OMIM: 609386) structural maintenance of (1101) 7172 707.1 1.4e-202
XP_016869996 (OMIM: 609386) PREDICTED: structural (1068) 6857 676.7 1.9e-193
XP_005251894 (OMIM: 609386) PREDICTED: structural (1086) 5466 542.7 4.5e-153
XP_016869997 (OMIM: 609386) PREDICTED: structural ( 880) 5442 540.3 1.9e-152
XP_005251895 (OMIM: 609386) PREDICTED: structural (1077) 4881 486.3 4.2e-136
XP_016869998 (OMIM: 609386) PREDICTED: structural ( 723) 4692 467.9 9.5e-131
XP_005251896 (OMIM: 609386) PREDICTED: structural (1063) 3777 379.9 4.5e-104
XP_016869999 (OMIM: 609386) PREDICTED: structural ( 685) 3720 374.2 1.5e-102
XP_011531410 (OMIM: 609387) PREDICTED: structural (1083) 503 64.3 4.5e-09
XP_016860403 (OMIM: 609387) PREDICTED: structural (1110) 414 55.7 1.7e-06
XP_016860402 (OMIM: 609387) PREDICTED: structural (1110) 414 55.7 1.7e-06
XP_011531409 (OMIM: 609387) PREDICTED: structural (1110) 414 55.7 1.7e-06
NP_078900 (OMIM: 609387) structural maintenance of (1091) 323 47.0 0.00075
NP_001135758 (OMIM: 609387) structural maintenance (1091) 323 47.0 0.00075
XP_016860404 (OMIM: 609387) PREDICTED: structural (1091) 323 47.0 0.00075
>>NP_055925 (OMIM: 609386) structural maintenance of chr (1101 aa)
initn: 7172 init1: 7172 opt: 7172 Z-score: 3757.8 bits: 707.1 E(85289): 1.4e-202
Smith-Waterman score: 7172; 99.9% identity (100.0% similar) in 1101 aa overlap (1-1101:1-1101)
10 20 30 40 50 60
pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EGQIPVTCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP
1030 1040 1050 1060 1070 1080
1090 1100
pF1KA0 NTWNLKAFQRRRRRITFTQPS
:::::::::::::::::::::
NP_055 NTWNLKAFQRRRRRITFTQPS
1090 1100
>>XP_016869996 (OMIM: 609386) PREDICTED: structural main (1068 aa)
initn: 6857 init1: 6857 opt: 6857 Z-score: 3593.9 bits: 676.7 E(85289): 1.9e-193
Smith-Waterman score: 6857; 99.9% identity (100.0% similar) in 1055 aa overlap (1-1055:1-1055)
10 20 30 40 50 60
pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGQIPVTCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP
:::::::::::::::::::::::::::::::::::
XP_016 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKDTRLSKKLLEKCL
1030 1040 1050 1060
1090 1100
pF1KA0 NTWNLKAFQRRRRRITFTQPS
>>XP_005251894 (OMIM: 609386) PREDICTED: structural main (1086 aa)
initn: 5455 init1: 5455 opt: 5466 Z-score: 2869.2 bits: 542.7 E(85289): 4.5e-153
Smith-Waterman score: 7026; 98.5% identity (98.6% similar) in 1101 aa overlap (1-1101:1-1086)
10 20 30 40 50 60
pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGQIPVTCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI
: ::::::::::::::::::::::::::::::::::::::::::::
XP_005 T---------------VFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI
850 860 870 880
910 920 930 940 950 960
pF1KA0 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KA0 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KA0 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP
1010 1020 1030 1040 1050 1060
1090 1100
pF1KA0 NTWNLKAFQRRRRRITFTQPS
:::::::::::::::::::::
XP_005 NTWNLKAFQRRRRRITFTQPS
1070 1080
>>XP_016869997 (OMIM: 609386) PREDICTED: structural main (880 aa)
initn: 5442 init1: 5442 opt: 5442 Z-score: 2857.9 bits: 540.3 E(85289): 1.9e-152
Smith-Waterman score: 5442; 99.9% identity (100.0% similar) in 841 aa overlap (1-841:1-841)
10 20 30 40 50 60
pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGQIPVTCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI
:
XP_016 TILDPFYQFSKYPPFQMDTTPHSPWFSKTFQTHWMKLMLY
850 860 870 880
>>XP_005251895 (OMIM: 609386) PREDICTED: structural main (1077 aa)
initn: 4863 init1: 4863 opt: 4881 Z-score: 2564.5 bits: 486.3 E(85289): 4.2e-136
Smith-Waterman score: 6956; 97.7% identity (97.8% similar) in 1101 aa overlap (1-1101:1-1077)
10 20 30 40 50 60
pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI
:::::.::::::::::::::::::::: :::::::::
XP_005 EGQIPVTCRIEEMENERHNLEARIKEK------------------------IEELQQALI
310 320 330
370 380 390 400 410 420
pF1KA0 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA0 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA0 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA0 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI
520 530 540 550 560 570
610 620 630 640 650 660
pF1KA0 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK
580 590 600 610 620 630
670 680 690 700 710 720
pF1KA0 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL
640 650 660 670 680 690
730 740 750 760 770 780
pF1KA0 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE
700 710 720 730 740 750
790 800 810 820 830 840
pF1KA0 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ
760 770 780 790 800 810
850 860 870 880 890 900
pF1KA0 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI
820 830 840 850 860 870
910 920 930 940 950 960
pF1KA0 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KA0 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KA0 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP
1000 1010 1020 1030 1040 1050
1090 1100
pF1KA0 NTWNLKAFQRRRRRITFTQPS
:::::::::::::::::::::
XP_005 NTWNLKAFQRRRRRITFTQPS
1060 1070
>>XP_016869998 (OMIM: 609386) PREDICTED: structural main (723 aa)
initn: 4692 init1: 4692 opt: 4692 Z-score: 2468.3 bits: 467.9 E(85289): 9.5e-131
Smith-Waterman score: 4692; 100.0% identity (100.0% similar) in 723 aa overlap (379-1101:1-723)
350 360 370 380 390 400
pF1KA0 DKHIEELQQALIVKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLR
::::::::::::::::::::::::::::::
XP_016 MIEDLQNELKTTENCENLQPQIDAITNDLR
10 20 30
410 420 430 440 450 460
pF1KA0 RIQDEKALCEGEIIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIQDEKALCEGEIIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVL
40 50 60 70 80 90
470 480 490 500 510 520
pF1KA0 WLRNNRDKFKQRVCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLRNNRDKFKQRVCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVR
100 110 120 130 140 150
530 540 550 560 570 580
pF1KA0 DNKKLRVNAVIAPKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNKKLRVNAVIAPKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHE
160 170 180 190 200 210
590 600 610 620 630 640
pF1KA0 VPVGTEKTRERIERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPVGTEKTRERIERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVD
220 230 240 250 260 270
650 660 670 680 690 700
pF1KA0 LEQRRHLEEQLKEIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQRRHLEEQLKEIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLE
280 290 300 310 320 330
710 720 730 740 750 760
pF1KA0 QKISSKLGSLKLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKISSKLGSLKLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKV
340 350 360 370 380 390
770 780 790 800 810 820
pF1KA0 DLILQNTTVISEKNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLILQNTTVISEKNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCN
400 410 420 430 440 450
830 840 850 860 870 880
pF1KA0 LGAEQTLPQEYQTQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGAEQTLPQEYQTQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPT
460 470 480 490 500 510
890 900 910 920 930 940
pF1KA0 IVQEYTKREEEIEQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVQEYTKREEEIEQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFS
520 530 540 550 560 570
950 960 970 980 990 1000
pF1KA0 SMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQ
580 590 600 610 620 630
1010 1020 1030 1040 1050 1060
pF1KA0 ELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTV
640 650 660 670 680 690
1070 1080 1090 1100
pF1KA0 LFVYNGPHMLEPNTWNLKAFQRRRRRITFTQPS
:::::::::::::::::::::::::::::::::
XP_016 LFVYNGPHMLEPNTWNLKAFQRRRRRITFTQPS
700 710 720
>>XP_005251896 (OMIM: 609386) PREDICTED: structural main (1063 aa)
initn: 3713 init1: 3713 opt: 3777 Z-score: 1989.5 bits: 379.9 E(85289): 4.5e-104
Smith-Waterman score: 6838; 96.5% identity (96.5% similar) in 1101 aa overlap (1-1101:1-1063)
10 20 30 40 50 60
pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLTYDICEVSPGPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GMVEIELFRASGNLVITREIDVAKNQSFWFINKKSTTQKIVEEKVAALNIQVGNLCQFLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLETSCKEKTEYLQKMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEEVKLVRDRVKEEVRKLK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 EGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGQIPVTCRIEEMENERHNLEARIKEKATDIKEASQKCKQKQDVIERKDKHIEELQQALI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLRRIQDEKALCEGE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVLWLRNNRDKFKQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 VCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIA
:::::::: ::::::::::::::
XP_005 VCEPIMLT--------------------------------------VRDNKKLRVNAVIA
490 500
550 560 570 580 590 600
pF1KA0 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERI
510 520 530 540 550 560
610 620 630 640 650 660
pF1KA0 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLK
570 580 590 600 610 620
670 680 690 700 710 720
pF1KA0 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLEQKISSKLGSLKL
630 640 650 660 670 680
730 740 750 760 770 780
pF1KA0 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE
690 700 710 720 730 740
790 800 810 820 830 840
pF1KA0 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCNLGAEQTLPQEYQ
750 760 770 780 790 800
850 860 870 880 890 900
pF1KA0 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTIVQEYTKREEEI
810 820 830 840 850 860
910 920 930 940 950 960
pF1KA0 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHT
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KA0 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDE
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KA0 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEP
990 1000 1010 1020 1030 1040
1090 1100
pF1KA0 NTWNLKAFQRRRRRITFTQPS
:::::::::::::::::::::
XP_005 NTWNLKAFQRRRRRITFTQPS
1050 1060
>>XP_016869999 (OMIM: 609386) PREDICTED: structural main (685 aa)
initn: 3713 init1: 3713 opt: 3720 Z-score: 1962.3 bits: 374.2 E(85289): 1.5e-102
Smith-Waterman score: 4358; 94.7% identity (94.7% similar) in 723 aa overlap (379-1101:1-685)
350 360 370 380 390 400
pF1KA0 DKHIEELQQALIVKQNEELDRQRRIGNTRKMIEDLQNELKTTENCENLQPQIDAITNDLR
::::::::::::::::::::::::::::::
XP_016 MIEDLQNELKTTENCENLQPQIDAITNDLR
10 20 30
410 420 430 440 450 460
pF1KA0 RIQDEKALCEGEIIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIQDEKALCEGEIIDKRRERETLEKEKKSVDDHIVRFDNLMNQKEDKLRQRFRDTYDAVL
40 50 60 70 80 90
470 480 490 500 510 520
pF1KA0 WLRNNRDKFKQRVCEPIMLTINMKDNKNAKYIENHIPSNDLRAFVFESQEDMEVFLKEVR
:::::::::::::::::::: ::
XP_016 WLRNNRDKFKQRVCEPIMLT--------------------------------------VR
100 110
530 540 550 560 570 580
pF1KA0 DNKKLRVNAVIAPKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNKKLRVNAVIAPKSSYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHE
120 130 140 150 160 170
590 600 610 620 630 640
pF1KA0 VPVGTEKTRERIERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPVGTEKTRERIERVIQETRLKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVD
180 190 200 210 220 230
650 660 670 680 690 700
pF1KA0 LEQRRHLEEQLKEIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQRRHLEEQLKEIHRKLQAVDSGLIALRETSKHLEHKDNELRQKKKELLERKTKKRQLE
240 250 260 270 280 290
710 720 730 740 750 760
pF1KA0 QKISSKLGSLKLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKISSKLGSLKLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTNLIKICTSLHIQKV
300 310 320 330 340 350
770 780 790 800 810 820
pF1KA0 DLILQNTTVISEKNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLILQNTTVISEKNKLESDYMAASSQLRLTEQHFIELDENRQRLLQKCKELMKRARQVCN
360 370 380 390 400 410
830 840 850 860 870 880
pF1KA0 LGAEQTLPQEYQTQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGAEQTLPQEYQTQVPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPT
420 430 440 450 460 470
890 900 910 920 930 940
pF1KA0 IVQEYTKREEEIEQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVQEYTKREEEIEQLTEELKGKKVELDQYRENISQVKERWLNPLKELVEKINEKFSNFFS
480 490 500 510 520 530
950 960 970 980 990 1000
pF1KA0 SMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQ
540 550 560 570 580 590
1010 1020 1030 1040 1050 1060
pF1KA0 ELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTV
600 610 620 630 640 650
1070 1080 1090 1100
pF1KA0 LFVYNGPHMLEPNTWNLKAFQRRRRRITFTQPS
:::::::::::::::::::::::::::::::::
XP_016 LFVYNGPHMLEPNTWNLKAFQRRRRRITFTQPS
660 670 680
>>XP_011531410 (OMIM: 609387) PREDICTED: structural main (1083 aa)
initn: 346 init1: 187 opt: 503 Z-score: 283.9 bits: 64.3 E(85289): 4.5e-09
Smith-Waterman score: 555; 21.2% identity (54.7% similar) in 1133 aa overlap (6-1069:5-1057)
10 20 30 40 50 60
pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
:. . ::. .:: ::. : .: . ... : : : ..:
XP_011 MAKRKEENFSSPKNAKR--PRQEELEDFDKDGDEDECKGTTLTAAEV--GIIESIHLKN
10 20 30 40 50
70 80 90 100 110
pF1KA0 FLTYDICEVSP---GPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRG
:. ... ..: : ..:..:: ::.:::... :. .::.:. . .:.... ::: :
XP_011 FMCHSM--LGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGRAVATNRGSSLKGFVKDG
60 70 80 90 100 110
120 130 140 150 160
pF1KA0 CSRGMVEIEL-------FRAS--GN-LVITREIDVAKNQSFWFINKKSTTQKIVEEKVAA
. . . : : :.:: :: ..: ..:.. ..:. . ::.: ..: .
XP_011 QNSADISITLRNRGDDAFKASVYGNSILIQQHISIDGSRSYKL---KSATGSVVSTRKEE
120 130 140 150 160 170
170 180 190 200 210 220
pF1KA0 LNIQVGNLCQFLPQDKVGEFAKLSKIELLEATEKSIGPPEMHKYHCELKNLREKEKQLET
: .. : .: .. : : ...: .. : ..: : :. : :: :..
XP_011 L---IAILDHF----NIQFFMKATQLEQMK---------EDYSYIMETKE-RTKE-QIHQ
180 190 200 210
230 240 250 260 270 280
pF1KA0 SCKEKTEYLQKMVQRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEY----E
. .. :: .. :...::. :.. . : .: : :. . :. ...... .
XP_011 GEERLTELKRQCVEKEERF-QSIAGLSTMKTNL---ESLKHEMAWAVVNEIEKQLNAIRD
220 230 240 250 260
290 300 310 320 330 340
pF1KA0 EVKLVRDRVKEEVRKLKEGQIPITCRIEEMENERHNLEARIKEKATDIKEASQKCKQ-KQ
..:. .::. . ::..: :. :..: :.. .... .... . . . . .: :
XP_011 NIKIGEDRAARLDRKMEEQQV----RLNEAEQKYKDIQDKLEKISEETNARAPECMALKA
270 280 290 300 310 320
350 360 370 380 390
pF1KA0 DVIERKDKHIEE-------LQQALIVKQNEELDRQRRIGNTRKMIED-LQNE-LKTTENC
::. .: . : :.. .:...: . .:: . .: .. :. : :. ..
XP_011 DVVAKKRAYNEAEVLYNRSLNEYKALKKDDE-QLCKRIEELKKSTDQSLEPERLERQKKI
330 340 350 360 370 380
400 410 420 430 440
pF1KA0 ENLQPQIDAITNDLRRIQDEKALCEGEIIDKRRERETLEKEKKSVDDHIVRFDN-----L
:. .. :. :. ...: . : ..:. ...:. .: : . ... :
XP_011 SWLKERVKAFQNQENSVNQEIEQFQQAIEKDKEEHGKIKREELDVK-HALSYNQRQLKEL
390 400 410 420 430 440
450 460 470 480 490 500
pF1KA0 MNQKEDKLRQRFRDTYDAVLWLRNN---RDKFKQRVCEPIMLTINMKDNKNAKYIENHIP
..: :.:. :: . :.: .. . .: . :. :...: . : ::. .
XP_011 KDSKTDRLK-RFGPNVPALLEAIDDAYRQGHFTYKPVGPLGACIHLRDPELALAIESCL-
450 460 470 480 490 500
510 520 530 540 550 560
pF1KA0 SNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIAPK---SSYADKAPSRSLNELKQYGF
.. :.:. ... : .:. . :.. . .. : : . .. . . :
XP_011 KGLLQAYCCHNHADERVLQALM---KRFYLPGTSRPPIIVSEFRNEIYDVRHRAAYHPDF
510 520 530 540 550
570 580 590 600 610
pF1KA0 FSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERIERVIQETR----LKQIYTAEEK
. : : : . : . :. : . ... : :.: . .. .::.
XP_011 PTVLTALEIDNAVVANSLIDMRGIETVLLIKNNSVARA--VMQSQKPPKNCREAFTADGD
560 570 580 590 600 610
620 630 640 650 660 670
pF1KA0 YVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLKEIHRKLQAVDSGLIALRE
: .:: : :: : ::. :: : ::..... .. ... : ::..
XP_011 QVFAGRYYS----SENTRPK---FLSRDVDSEIS-DLENEVENKTAQILNLQQHLSALEK
620 630 640 650 660
680 690 700 710 720 730
pF1KA0 TSKHLEHKDNELRQKKKELLER-KTKKRQLEQKISSKLGSLKLMEQ-------DTCNLEE
:: :: :::.: . . ..:..:: .... .. .:. : .::.
XP_011 DIKH-----NE------ELLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLED
670 680 690 700 710
740 750 760 770 780
pF1KA0 EERKASTKIKEI--NVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVISE--KNKLES
: .. ..:.: . .... : : . .:: . . . . . ... . ... :..:.
XP_011 EAQENKSKMKMVEEHMEQQKENMEHLKSLKIEAENKYDAIKFKINQLSELADPLKDELNL
720 730 740 750 760 770
790 800 810 820 830
pF1KA0 DYMAASSQLR-------LTEQHFIELDENRQRLLQKCKEL---MKRARQVCNLGAEQTLP
...: : ..:. :......: .: ::: :..:::.: :
XP_011 ADSEVDNQKRGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQIC--------P
780 790 800 810 820
840 850 860 870 880 890
pF1KA0 QEYQTQ-VPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGLNPTI--VQEY
.. ... .: . . . : . .: . . . .. . . . :. . ....
XP_011 ERIEVEKSASILDKEINRLRQKIQAEHASHGDREEIMRQYQEARETYLDLDSKVRTLKKF
830 840 850 860 870 880
900 910 920 930 940 950
pF1KA0 TKREEEIEQLTEELKGKKVELDQYRENISQVKERWLN--PLKELVEKINEKFSNFFSSMQ
: :: . ...: . .. ..:.. . ..: .. :. . . :.:..:.
XP_011 IKLLGEI--MEHRFKTYQ-QFRSFRQKNKPNLYYYINLFQMQCLTLRCKLYFDNLLSQRA
890 900 910 920 930 940
960 970 980 990 1000 1010
pF1KA0 CAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELN
:.... .:: .: .. ... .... . :::::: ::. ....: .
XP_011 YCGKMNFDHKNET----LSISVQPGEGNKAAFNDM--RALSGGERSFSTVCFILSLWSIA
950 960 970 980 990
1020 1030 1040 1050 1060 1070
pF1KA0 RCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFV
. ::: .::.. :: .:.: ....... : .. :....::. ...:: :. . .:
XP_011 ESPFRCLDEFDVYMDMVNRRIAMDLILKMADSQRFRQFILLTPQSMSSLPSSKLIRILRM
1000 1010 1020 1030 1040 1050
1080 1090 1100
pF1KA0 YNGPHMLEPNTWNLKAFQRRRRRITFTQPS
XP_011 SDPERGQTTLPFRPVTQEEDDDQR
1060 1070 1080
>>XP_016860403 (OMIM: 609387) PREDICTED: structural main (1110 aa)
initn: 371 init1: 187 opt: 414 Z-score: 237.4 bits: 55.7 E(85289): 1.7e-06
Smith-Waterman score: 586; 21.5% identity (54.9% similar) in 1143 aa overlap (6-1069:5-1084)
10 20 30 40 50 60
pF1KA0 MATPSKKTSTPSPQPSKRALPRDPSSEVPSKRKNSAPQLPLLQSSGPFVEGSIVRISMEN
:. . ::. .:: ::. : .: . ... : : : ..:
XP_016 MAKRKEENFSSPKNAKR--PRQEELEDFDKDGDEDECKGTTLTAAEV--GIIESIHLKN
10 20 30 40 50
70 80 90 100 110
pF1KA0 FLTYDICEVSP---GPHLNMIVGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRG
:. ... ..: : ..:..:: ::.:::... :. .::.:. . .:.... ::: :
XP_016 FMCHSM--LGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGRAVATNRGSSLKGFVKDG
60 70 80 90 100 110
120 130 140 150 160
pF1KA0 CSRGMVEIEL-------FRAS--GN-LVITREIDVAKNQSFWFINKKSTTQKIV----EE
. . . : : :.:: :: ..: ..:.. ..:. . ::.: ..: ::
XP_016 QNSADISITLRNRGDDAFKASVYGNSILIQQHISIDGSRSYKL---KSATGSVVSTRKEE
120 130 140 150 160 170
170 180 190 200 210
pF1KA0 KVAAL---NIQVGNLCQFLPQDKVGEFAKLSKIE--LLEATEKSIGPPEMHKYHCELKNL
.: : :::: : . : :. .: . :: : . :. .:.. . . .
XP_016 LIAILDHFNIQVDNPVSVLTQEMSKQFLQ-SKNEGDKYKFFMKATQLEQMKEDYSYIMET
180 190 200 210 220
220 230 240 250 260 270
pF1KA0 REKEK-QLETSCKEKTEYLQKMVQRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYEN
.:. : :.. . .. :: .. :...::. :.. . : .: : :. . :. ..
XP_016 KERTKEQIHQGEERLTELKRQCVEKEERF-QSIAGLSTMKTNL---ESLKHEMAWAVVNE
230 240 250 260 270 280
280 290 300 310 320 330
pF1KA0 VRQEY----EEVKLVRDRVKEEVRKLKEGQIPITCRIEEMENERHNLEARIKEKATDIKE
.... ...:. .::. . ::..: :. :..: :.. .... .... . . .
XP_016 IEKQLNAIRDNIKIGEDRAARLDRKMEEQQV----RLNEAEQKYKDIQDKLEKISEETNA
290 300 310 320 330 340
340 350 360 370 380
pF1KA0 ASQKCKQ-KQDVIERKDKHIEE-------LQQALIVKQNEELDRQRRIGNTRKMIED-LQ
. .: : ::. .: . : :.. .:...: . .:: . .: .. :.
XP_016 RAPECMALKADVVAKKRAYNEAEVLYNRSLNEYKALKKDDE-QLCKRIEELKKSTDQSLE
350 360 370 380 390 400
390 400 410 420 430 440
pF1KA0 NE-LKTTENCENLQPQIDAITNDLRRIQDEKALCEGEIIDKRRERETLEKEKKSVDDHIV
: :. .. :. .. :. :. ...: . : ..:. ...:. .: : .
XP_016 PERLERQKKISWLKERVKAFQNQENSVNQEIEQFQQAIEKDKEEHGKIKREELDVK-HAL
410 420 430 440 450
450 460 470 480 490
pF1KA0 RFDN-----LMNQKEDKLRQRFRDTYDAVLWLRNN---RDKFKQRVCEPIMLTINMKDNK
... : ..: :.:. :: . :.: .. . .: . :. :...: .
XP_016 SYNQRQLKELKDSKTDRLK-RFGPNVPALLEAIDDAYRQGHFTYKPVGPLGACIHLRDPE
460 470 480 490 500 510
500 510 520 530 540 550
pF1KA0 NAKYIENHIPSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIAPK---SSYADKAPSR
: ::. . .. :.:. ... : .:. . :.. . .. : : . .. .
XP_016 LALAIESCL-KGLLQAYCCHNHADERVLQALM---KRFYLPGTSRPPIIVSEFRNEIYDV
520 530 540 550 560 570
560 570 580 590 600
pF1KA0 SLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTEKTRERIERVIQETR----
. : . : : : . : . :. : . ... : :.: .
XP_016 RHRAAYHPDFPTVLTALEIDNAVVANSLIDMRGIETVLLIKNNSVARA--VMQSQKPPKN
580 590 600 610 620 630
610 620 630 640 650 660
pF1KA0 LKQIYTAEEKYVVKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLKEIHRKLQA
.. .::. : .:: : :: : ::. :: : ::..... ..
XP_016 CREAFTADGDQVFAGRYYS----SENTRPK---FLSRDVDSEIS-DLENEVENKTAQILN
640 650 660 670 680
670 680 690 700 710 720
pF1KA0 VDSGLIALRETSKHLEHKDNELRQKKKELLER-KTKKRQLEQKISSKLGSLKLMEQ----
... : ::.. :: :: :::.: . . ..:..:: .... .. .:.
XP_016 LQQHLSALEKDIKH-----NE------ELLKRCQLHYKELKMKIRKNISEIRELENIEEH
690 700 710 720 730
730 740 750 760 770
pF1KA0 ---DTCNLEEEERKASTKIKEI--NVQKAKLVTELTNLIKICTSLHIQKVDLILQNTTVI
: .::.: .. ..:.: . .... : : . .:: . . . . . ... . .
XP_016 QSVDIATLEDEAQENKSKMKMVEEHMEQQKENMEHLKSLKIEAENKYDAIKFKINQLSEL
740 750 760 770 780 790
780 790 800 810 820
pF1KA0 SE--KNKLESDYMAASSQLR-------LTEQHFIELDENRQRLLQKCKEL---MKRARQV
.. :..:. ...: : ..:. :......: .: ::: :..:::.
XP_016 ADPLKDELNLADSEVDNQKRGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQI
800 810 820 830 840 850
830 840 850 860 870 880
pF1KA0 CNLGAEQTLPQEYQTQ-VPTIPNGHNSSLPMVFQDLPNTLDEIDALLTEERSRASCFTGL
: :.. ... .: . . . : . .: . . . .. . . . :
XP_016 C--------PERIEVEKSASILDKEINRLRQKIQAEHASHGDREEIMRQYQEARETYLDL
860 870 880 890 900
890 900 910 920 930 940
pF1KA0 NPTI--VQEYTKREEEIEQLTEELKGKKVELDQYRENISQVKERWLN--PLKELVEKINE
. . .... : :: . ...: . .. ..:.. . ..: .. :. . .
XP_016 DSKVRTLKKFIKLLGEI--MEHRFKTYQ-QFRSFRQKNKPNLYYYINLFQMQCLTLRCKL
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA0 KFSNFFSSMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTM
:.:..:. :.... .:: .: .. ... .... . :::::: ::.
XP_016 YFDNLLSQRAYCGKMNFDHKNET----LSISVQPGEGNKAAFNDM--RALSGGERSFSTV
970 980 990 1000 1010
1010 1020 1030 1040 1050 1060
pF1KA0 LYLMALQELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLP
....: . . ::: .::.. :: .:.: ....... : .. :....::. ...::
XP_016 CFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDLILKMADSQRFRQFILLTPQSMSSLP
1020 1030 1040 1050 1060 1070
1070 1080 1090 1100
pF1KA0 YSEKMTVLFVYNGPHMLEPNTWNLKAFQRRRRRITFTQPS
:. . .:
XP_016 SSKLIRILRMSDPERGQTTLPFRPVTQEEDDDQR
1080 1090 1100 1110
1101 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:49:31 2016 done: Thu Nov 3 09:49:33 2016
Total Scan time: 15.650 Total Display time: 0.510
Function used was FASTA [36.3.4 Apr, 2011]