Result of FASTA (omim) for
pFN21ASDF0168
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDF0168, 567 aa
1>>>pF1KSDF0168 567 - 567 aa - 567 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4451+/-0.000356; mu= 18.4035+/- 0.022
mean_var=74.5573+/-15.341, 0's: 0 Z-trim(114.7): 51 B-trim: 1365 in 1/49
Lambda= 0.148535
statistics sampled from 24605 (24659) to 24605 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.289), width: 16
Scan time: 9.870
The best scores are: opt bits E(85289)
NP_690863 (OMIM: 609742) L-amino-acid oxidase isof ( 567) 3817 827.5 0
NP_001244947 (OMIM: 609742) L-amino-acid oxidase i ( 589) 3793 822.4 0
NP_758962 (OMIM: 609742) L-amino-acid oxidase isof ( 589) 3793 822.4 0
NP_001244946 (OMIM: 609742) L-amino-acid oxidase i ( 589) 3793 822.4 0
NP_000889 (OMIM: 309860) amine oxidase [flavin-con ( 520) 400 95.3 5.3e-19
NP_000231 (OMIM: 300615,309850) amine oxidase [fla ( 527) 356 85.8 3.7e-16
XP_016885013 (OMIM: 309860) PREDICTED: amine oxida ( 504) 352 85.0 6.4e-16
XP_005272665 (OMIM: 309860) PREDICTED: amine oxida ( 504) 352 85.0 6.4e-16
XP_016885012 (OMIM: 309860) PREDICTED: amine oxida ( 504) 352 85.0 6.4e-16
NP_787034 (OMIM: 615854) spermine oxidase isoform ( 502) 233 59.5 3e-08
NP_787036 (OMIM: 615854) spermine oxidase isoform ( 532) 233 59.5 3.2e-08
NP_001257387 (OMIM: 300615,309850) amine oxidase [ ( 394) 223 57.3 1.1e-07
NP_001009999 (OMIM: 609132,616728) lysine-specific ( 876) 193 51.1 1.8e-05
XP_016856206 (OMIM: 609132,616728) PREDICTED: lysi ( 802) 187 49.7 4.1e-05
XP_016856205 (OMIM: 609132,616728) PREDICTED: lysi ( 822) 187 49.8 4.2e-05
XP_006710536 (OMIM: 609132,616728) PREDICTED: lysi ( 828) 187 49.8 4.2e-05
NP_055828 (OMIM: 609132,616728) lysine-specific hi ( 852) 187 49.8 4.3e-05
XP_006710535 (OMIM: 609132,616728) PREDICTED: lysi ( 858) 187 49.8 4.3e-05
XP_005245843 (OMIM: 609132,616728) PREDICTED: lysi ( 872) 187 49.8 4.4e-05
XP_006710537 (OMIM: 609132,616728) PREDICTED: lysi ( 878) 187 49.8 4.4e-05
NP_787035 (OMIM: 615854) spermine oxidase isoform ( 190) 173 46.3 0.0001
XP_005248985 (OMIM: 613081) PREDICTED: lysine-spec ( 678) 177 47.6 0.00016
XP_011512688 (OMIM: 613081) PREDICTED: lysine-spec ( 690) 177 47.6 0.00016
XP_011512687 (OMIM: 613081) PREDICTED: lysine-spec ( 691) 177 47.6 0.00016
XP_016865934 (OMIM: 613081) PREDICTED: lysine-spec ( 700) 177 47.6 0.00016
XP_016865931 (OMIM: 613081) PREDICTED: lysine-spec ( 802) 177 47.6 0.00018
XP_005248983 (OMIM: 613081) PREDICTED: lysine-spec ( 822) 177 47.6 0.00019
XP_005248982 (OMIM: 613081) PREDICTED: lysine-spec ( 823) 177 47.6 0.00019
XP_016865930 (OMIM: 613081) PREDICTED: lysine-spec ( 831) 177 47.6 0.00019
XP_016865932 (OMIM: 613081) PREDICTED: lysine-spec ( 832) 177 47.6 0.00019
XP_016865929 (OMIM: 613081) PREDICTED: lysine-spec ( 832) 177 47.6 0.00019
XP_016865935 (OMIM: 613081) PREDICTED: lysine-spec ( 464) 153 42.3 0.0041
NP_694587 (OMIM: 613081) lysine-specific histone d ( 590) 153 42.4 0.005
XP_016856209 (OMIM: 609132,616728) PREDICTED: lysi ( 551) 151 41.9 0.0064
XP_016856208 (OMIM: 609132,616728) PREDICTED: lysi ( 551) 151 41.9 0.0064
XP_016856207 (OMIM: 609132,616728) PREDICTED: lysi ( 557) 151 41.9 0.0064
>>NP_690863 (OMIM: 609742) L-amino-acid oxidase isoform (567 aa)
initn: 3817 init1: 3817 opt: 3817 Z-score: 4418.9 bits: 827.5 E(85289): 0
Smith-Waterman score: 3817; 100.0% identity (100.0% similar) in 567 aa overlap (1-567:1-567)
10 20 30 40 50 60
pF1KSD MAPLALHLLVLVPILLSLVASQDWKAERSQDPFEKCMQDPDYEQLLKVVTWGLNRTLKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MAPLALHLLVLVPILLSLVASQDWKAERSQDPFEKCMQDPDYEQLLKVVTWGLNRTLKPQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRIFTYRDQNTGWIGELGAMRMPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 RVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRIFTYRDQNTGWIGELGAMRMPSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD HRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYVVEKVPEKLGYALRPQEKGHSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 HRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYVVEKVPEKLGYALRPQEKGHSPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGEGNLSRPAVQLLGDVMSEDGFFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 DIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGEGNLSRPAVQLLGDVMSEDGFFY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 LSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD IETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 IETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD RPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASYTWSDAAAAFAGLSREEALRLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 RPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASYTWSDAAAAFAGLSREEALRLAL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD DDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQPPALWQTEKDDWTVPYGRIYFAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 DDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQPPALWQTEKDDWTVPYGRIYFAG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGVASSPSHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 EHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGVASSPSHD
490 500 510 520 530 540
550 560
pF1KSD LAKEEGSHPPVQGQLSLQNTTHTRTSH
:::::::::::::::::::::::::::
NP_690 LAKEEGSHPPVQGQLSLQNTTHTRTSH
550 560
>>NP_001244947 (OMIM: 609742) L-amino-acid oxidase isofo (589 aa)
initn: 3793 init1: 3793 opt: 3793 Z-score: 4390.9 bits: 822.4 E(85289): 0
Smith-Waterman score: 3793; 99.6% identity (99.8% similar) in 565 aa overlap (3-567:25-589)
10 20 30
pF1KSD MAPLALHLLVLVPILLSLVASQDWKAERSQDPFEKCMQ
: .:::::::::::::::::::::::::::::::::
NP_001 MPNDDFCPGLTIKAMGAERAPQRQPCTLHLLVLVPILLSLVASQDWKAERSQDPFEKCMQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD DPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD FTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD VEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD GNLSRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNLSRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLS
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD GLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPR
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD HMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASY
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD TWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD PALWQTEKDDWTVPYGRIYFAGEHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PALWQTEKDDWTVPYGRIYFAGEHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPE
490 500 510 520 530 540
520 530 540 550 560
pF1KSD GHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
550 560 570 580
>>NP_758962 (OMIM: 609742) L-amino-acid oxidase isoform (589 aa)
initn: 3793 init1: 3793 opt: 3793 Z-score: 4390.9 bits: 822.4 E(85289): 0
Smith-Waterman score: 3793; 99.6% identity (99.8% similar) in 565 aa overlap (3-567:25-589)
10 20 30
pF1KSD MAPLALHLLVLVPILLSLVASQDWKAERSQDPFEKCMQ
: .:::::::::::::::::::::::::::::::::
NP_758 MPNDDFCPGLTIKAMGAERAPQRQPCTLHLLVLVPILLSLVASQDWKAERSQDPFEKCMQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD DPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 DPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD FTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 FTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD VEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 VEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD GNLSRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 GNLSRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLS
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD GLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 GLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPR
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD HMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 HMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASY
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD TWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 TWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD PALWQTEKDDWTVPYGRIYFAGEHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 PALWQTEKDDWTVPYGRIYFAGEHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPE
490 500 510 520 530 540
520 530 540 550 560
pF1KSD GHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 GHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
550 560 570 580
>>NP_001244946 (OMIM: 609742) L-amino-acid oxidase isofo (589 aa)
initn: 3793 init1: 3793 opt: 3793 Z-score: 4390.9 bits: 822.4 E(85289): 0
Smith-Waterman score: 3793; 99.6% identity (99.8% similar) in 565 aa overlap (3-567:25-589)
10 20 30
pF1KSD MAPLALHLLVLVPILLSLVASQDWKAERSQDPFEKCMQ
: .:::::::::::::::::::::::::::::::::
NP_001 MPNDDFCPGLTIKAMGAERAPQRQPCTLHLLVLVPILLSLVASQDWKAERSQDPFEKCMQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD DPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD FTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD VEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD GNLSRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNLSRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLS
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD GLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPR
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD HMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASY
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD TWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD PALWQTEKDDWTVPYGRIYFAGEHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PALWQTEKDDWTVPYGRIYFAGEHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPE
490 500 510 520 530 540
520 530 540 550 560
pF1KSD GHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
550 560 570 580
>>NP_000889 (OMIM: 309860) amine oxidase [flavin-contain (520 aa)
initn: 350 init1: 197 opt: 400 Z-score: 462.2 bits: 95.3 E(85289): 5.3e-19
Smith-Waterman score: 415; 24.6% identity (55.3% similar) in 488 aa overlap (62-527:7-475)
40 50 60 70 80 90
pF1KSD PFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEAD
:.:::.:..:..:::.: :.: .:..:::
NP_000 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR
10 20 30
100 110 120 130 140 150
pF1KSD NRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHE
.:.::: .: :.:.. .. :.. :...::: .: . :::. : .. .. .:.
NP_000 DRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRIL-RLAKELGLETYKVNEVER----LIHH
40 50 60 70 80 90
160 170 180 190 200
pF1KSD VKLRNYVVEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKA--MKKFERH
:: ..: : . . . . .. . .... ... . . :: ....
NP_000 VKGKSY-----PFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNM
100 110 120 130 140
210 220 230 240 250
pF1KSD TLLEYLLGEGNLSRPAVQL---------LGDVMSEDGFFYLSFAEALRAHSCL---SDRL
:. : :: . .. : :: ... .....: ... . . . ..
NP_000 TMKE-LLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGG
150 160 170 180 190 200
260 270 280 290 300 310
pF1KSD QYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADV
: ..::: . . ... :. : :. ::. . : ..: :. . : .. .:
NP_000 QERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVE------TLNHEMYEAKY
210 220 230 240 250
320 330 340 350 360 370
pF1KSD VLLTASGPAVK-RITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGH--S
:. .: :.. .: :.:::: .. . :. . : .. ...::::.. : .
NP_000 VI-SAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIID
260 270 280 290 300 310
380 390 400 410 420 430
pF1KSD NTDRPSRMIFYPPPREGALL-LASYTWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQ
. . : . . :: . .. . : .: :..:: :. . : . : . .
NP_000 GEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSL-EA
320 330 340 350 360 370
440 450 460 470 480 490
pF1KSD LWDGTGVVKRWAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYGRIYFAGEHTA-YPHGWVE
: : : :.:.: : ... ::.. : :::::: .:: . :..:
NP_000 LEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYME
380 390 400 410 420 430
500 510 520 530 540
pF1KSD TAVKSALRAAIKINSRKG--PASDTASPEGHASDMEGQGHVHGVASSPSHDLAKEEGSHP
::... ::: .: : : .. . : .. :. .:
NP_000 GAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIG
440 450 460 470 480 490
550 560
pF1KSD PVQGQLSLQNTTHTRTSH
NP_000 LTTIFSATALGFLAHKRGLLVRV
500 510 520
>>NP_000231 (OMIM: 300615,309850) amine oxidase [flavin- (527 aa)
initn: 331 init1: 189 opt: 356 Z-score: 411.1 bits: 85.8 E(85289): 3.7e-16
Smith-Waterman score: 365; 25.3% identity (52.2% similar) in 490 aa overlap (62-513:16-468)
40 50 60 70 80 90
pF1KSD PFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEAD
:.:.:.:..:: :::.:.. : .: .:::
NP_000 MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEAR
10 20 30 40
100 110 120 130 140
pF1KSD NRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTK------FTQYDKN-
.:.::: .: :.... .. ::. :...::: .: . ::.. : ..:: :.
NP_000 DRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRIL-RLSKELGIETYKVNVSERLVQYVKGK
50 60 70 80 90 100
150 160 170 180 190
pF1KSD ----------TWTEVHEVKLRNYVVEKVPEKLGYAL---RPQEKGHSPEDIYQMALNQAL
.:. . . : . .. ...: . : : :. : .. ....
NP_000 TYPFRGAFPPVWNPIAYLDYNN--LWRTIDNMGKEIPTDAPWEAQHA--DKWD---KMTM
110 120 130 140 150
200 210 220 230 240
pF1KSD KDLKALGC-RKAMKKFERHTLLEYLLGEGNL-SRP----AVQLLGDVMSEDGFFYLSFAE
:.: : :. ..: ::. . :. :.: :. .: : . :
NP_000 KELIDKICWTKTARRFA------YLFVNINVTSEPHEVSALWFLWYVKQCGG--------
160 170 180 190 200
250 260 270 280 290 300
pF1KSD ALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSP
. : : ... : ..::: . . ... :. : :: ::. . :. .. .. .
NP_000 TTRIFS-VTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHE
210 220 230 240 250 260
310 320 330 340 350 360
pF1KSD PARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWR
. :..: ::: .: : : :: . .. ..:: . . : .. ... ::.
NP_000 HYECKYVINAIPPTLTA------KIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWK
270 280 290 300 310
370 380 390 400 410
pF1KSD EEHIEGGH--SNTDRPSRMIFYPPPREGAL-LLASYTWSDAAAAFAGLSRE-------EA
.. : . : : . . .:.: . .. . : .: : .: :
NP_000 KKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICEL
320 330 340 350 360 370
420 430 440 450 460 470
pF1KSD LRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYG
.: . ::: :: . : : :.:.: : ... ::.. : :
NP_000 YAKVLGSQEALH-PVHYEE-------KNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVG
380 390 400 410 420
480 490 500 510 520 530
pF1KSD RIYFAGEHTAYP-HGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGV
::.::: .:: :..: ::... ::: .. . : ...
NP_000 RIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITH
430 440 450 460 470 480
540 550 560
pF1KSD ASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
NP_000 TFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
490 500 510 520
>>XP_016885013 (OMIM: 309860) PREDICTED: amine oxidase [ (504 aa)
initn: 302 init1: 149 opt: 352 Z-score: 406.8 bits: 85.0 E(85289): 6.4e-16
Smith-Waterman score: 367; 23.8% identity (54.4% similar) in 478 aa overlap (72-527:1-459)
50 60 70 80 90 100
pF1KSD YEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRIFTY
..:::.: :.: .:..::: .:.::: .:
XP_016 MAAAKLLHDSGLNVVVLEARDRVGGRTYTL
10 20 30
110 120 130 140 150 160
pF1KSD RDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYVVEK
:.:.. .. :.. :...::: .: . :::. : .. .. .:.:: ..:
XP_016 RNQKVKYVDLGGSYVGPTQNRIL-RLAKELGLETYKVNEVER----LIHHVKGKSY----
40 50 60 70 80
170 180 190 200 210
pF1KSD VPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKA--MKKFERHTLLEYLLGEG
: . . . . .. . .... ... . . :: .... :. : :: .
XP_016 -PFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKE-LLDKL
90 100 110 120 130
220 230 240 250 260
pF1KSD NLSRPAVQL---------LGDVMSEDGFFYLSFAEALRAHSCL---SDRLQYSRIVGGWD
.. : :: ... .....: ... . . . .. : ..:::
XP_016 CWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSG
140 150 160 170 180 190
270 280 290 300 310 320
pF1KSD LLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAV
. . ... :. : :. ::. . : ..: :. . : .. .: :. .: :..
XP_016 QVSERIMDLLGDRVKLERPVIYIDQTRENVLVE------TLNHEMYEAKYVI-SAIPPTL
200 210 220 230 240 250
330 340 350 360 370 380
pF1KSD K-RITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGH--SNTDRPSRMIF
.: :.:::: .. . :. . : .. ...::::.. : .. . : . .
XP_016 GMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTL
260 270 280 290 300 310
390 400 410 420 430 440
pF1KSD YPPPREGALL-LASYTWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKR
:: . .. . : .: :..:: :. . : . : . . : :
XP_016 DDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSL-EALEPVHYEEKN
320 330 340 350 360 370
450 460 470 480 490 500
pF1KSD WAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYGRIYFAGEHTA-YPHGWVETAVKSALRAA
: :.:.: : ... ::.. : :::::: .:: . :..: ::... :::
XP_016 WCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAA
380 390 400 410 420 430
510 520 530 540 550
pF1KSD IKINSRKG--PASDTASPEGHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQN
.: : : .. . : .. :. .:
XP_016 REILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATAL
440 450 460 470 480 490
>>XP_005272665 (OMIM: 309860) PREDICTED: amine oxidase [ (504 aa)
initn: 302 init1: 149 opt: 352 Z-score: 406.8 bits: 85.0 E(85289): 6.4e-16
Smith-Waterman score: 367; 23.8% identity (54.4% similar) in 478 aa overlap (72-527:1-459)
50 60 70 80 90 100
pF1KSD YEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRIFTY
..:::.: :.: .:..::: .:.::: .:
XP_005 MAAAKLLHDSGLNVVVLEARDRVGGRTYTL
10 20 30
110 120 130 140 150 160
pF1KSD RDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYVVEK
:.:.. .. :.. :...::: .: . :::. : .. .. .:.:: ..:
XP_005 RNQKVKYVDLGGSYVGPTQNRIL-RLAKELGLETYKVNEVER----LIHHVKGKSY----
40 50 60 70 80
170 180 190 200 210
pF1KSD VPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKA--MKKFERHTLLEYLLGEG
: . . . . .. . .... ... . . :: .... :. : :: .
XP_005 -PFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKE-LLDKL
90 100 110 120 130
220 230 240 250 260
pF1KSD NLSRPAVQL---------LGDVMSEDGFFYLSFAEALRAHSCL---SDRLQYSRIVGGWD
.. : :: ... .....: ... . . . .. : ..:::
XP_005 CWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSG
140 150 160 170 180 190
270 280 290 300 310 320
pF1KSD LLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAV
. . ... :. : :. ::. . : ..: :. . : .. .: :. .: :..
XP_005 QVSERIMDLLGDRVKLERPVIYIDQTRENVLVE------TLNHEMYEAKYVI-SAIPPTL
200 210 220 230 240 250
330 340 350 360 370 380
pF1KSD K-RITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGH--SNTDRPSRMIF
.: :.:::: .. . :. . : .. ...::::.. : .. . : . .
XP_005 GMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTL
260 270 280 290 300 310
390 400 410 420 430 440
pF1KSD YPPPREGALL-LASYTWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKR
:: . .. . : .: :..:: :. . : . : . . : :
XP_005 DDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSL-EALEPVHYEEKN
320 330 340 350 360 370
450 460 470 480 490 500
pF1KSD WAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYGRIYFAGEHTA-YPHGWVETAVKSALRAA
: :.:.: : ... ::.. : :::::: .:: . :..: ::... :::
XP_005 WCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAA
380 390 400 410 420 430
510 520 530 540 550
pF1KSD IKINSRKG--PASDTASPEGHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQN
.: : : .. . : .. :. .:
XP_005 REILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATAL
440 450 460 470 480 490
>>XP_016885012 (OMIM: 309860) PREDICTED: amine oxidase [ (504 aa)
initn: 302 init1: 149 opt: 352 Z-score: 406.8 bits: 85.0 E(85289): 6.4e-16
Smith-Waterman score: 367; 23.8% identity (54.4% similar) in 478 aa overlap (72-527:1-459)
50 60 70 80 90 100
pF1KSD YEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRIFTY
..:::.: :.: .:..::: .:.::: .:
XP_016 MAAAKLLHDSGLNVVVLEARDRVGGRTYTL
10 20 30
110 120 130 140 150 160
pF1KSD RDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYVVEK
:.:.. .. :.. :...::: .: . :::. : .. .. .:.:: ..:
XP_016 RNQKVKYVDLGGSYVGPTQNRIL-RLAKELGLETYKVNEVER----LIHHVKGKSY----
40 50 60 70 80
170 180 190 200 210
pF1KSD VPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKA--MKKFERHTLLEYLLGEG
: . . . . .. . .... ... . . :: .... :. : :: .
XP_016 -PFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKE-LLDKL
90 100 110 120 130
220 230 240 250 260
pF1KSD NLSRPAVQL---------LGDVMSEDGFFYLSFAEALRAHSCL---SDRLQYSRIVGGWD
.. : :: ... .....: ... . . . .. : ..:::
XP_016 CWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSG
140 150 160 170 180 190
270 280 290 300 310 320
pF1KSD LLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAV
. . ... :. : :. ::. . : ..: :. . : .. .: :. .: :..
XP_016 QVSERIMDLLGDRVKLERPVIYIDQTRENVLVE------TLNHEMYEAKYVI-SAIPPTL
200 210 220 230 240 250
330 340 350 360 370 380
pF1KSD K-RITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGH--SNTDRPSRMIF
.: :.:::: .. . :. . : .. ...::::.. : .. . : . .
XP_016 GMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTL
260 270 280 290 300 310
390 400 410 420 430 440
pF1KSD YPPPREGALL-LASYTWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKR
:: . .. . : .: :..:: :. . : . : . . : :
XP_016 DDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSL-EALEPVHYEEKN
320 330 340 350 360 370
450 460 470 480 490 500
pF1KSD WAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYGRIYFAGEHTA-YPHGWVETAVKSALRAA
: :.:.: : ... ::.. : :::::: .:: . :..: ::... :::
XP_016 WCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAA
380 390 400 410 420 430
510 520 530 540 550
pF1KSD IKINSRKG--PASDTASPEGHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQN
.: : : .. . : .. :. .:
XP_016 REILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATAL
440 450 460 470 480 490
>>NP_787034 (OMIM: 615854) spermine oxidase isoform 2 [H (502 aa)
initn: 251 init1: 98 opt: 233 Z-score: 269.0 bits: 59.5 E(85289): 3e-08
Smith-Waterman score: 250; 25.7% identity (50.0% similar) in 502 aa overlap (52-499:18-489)
30 40 50 60 70 80
pF1KSD QDWKAERSQDPFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDA
:: : .: ::.:.:::.:::.:::.: .
NP_787 MQSCESSGDSADDPLSRGLRRRGQP-RVVVIGAGLAGLAAAKALLEQ
10 20 30 40
90 100 110 120 130
pF1KSD GHK-VTILEADNRIGGRIFTYRDQNTGWIGELGAMRMPSSH-RILHKLCQGLGLNLTKFT
: ::.:::...::::. . . .. . :::: . .:: ...: .. :: : . :
NP_787 GFTDVTVLEASSHIGGRVQSVKLGHATF--ELGATWIHGSHGNPIYHLAEANGL-LEETT
50 60 70 80 90 100
140 150 160 170 180 190
pF1KSD QYDKNTWTEVHEVKLRNYVVEKVPEKLGYALRPQEKGHS-PEDIYQMALNQALKDLKALG
. ... : ...: . : : : ..:. :.:. . ..::
NP_787 DGERS----VGRISLYS--------KNGVACYLTNHGRRIPKDVVE-----EFSDLYNE-
110 120 130 140
200 210 220 230 240 250
pF1KSD CRKAMKKFERHTL---LEYLLGEGNLSRPAVQ--LLGDVMSEDGFFYLSFA---EALRAH
. ..: :: : . : ..: :. . .: . .. :..: . :...
NP_787 VYNLTQEFFRHDKPVNAESQNSVGVFTREEVRNRIRNDPDDPEATKRLKLAMIQQYLKVE
150 160 170 180 190 200
260 270 280 290 300
pF1KSD SCLSDRLQYSRI----VGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSPP
:: :. ..... : : .: : ::.. :: . .:: :. . :
NP_787 SCESSSHSMDEVSLSAFGEWTEIPGAHHIIPSGFMR----VVELLAEGIPAHV-IQLGKP
210 220 230 240 250 260
310 320 330 340 350
pF1KSD ARNLKVLKADVVLLTASGPAV------KRIT---FSPPLPRHMQEALRRLHYVPATKVFL
.: .. .:.. :: . :: : : :: . :..:: . :.::
NP_787 VRCIHWDQASA---RPRGPEIEPRGVLKRQYTSFFRPGLPTEKVAAIHRLGIGTTDKIFL
270 280 290 300 310
360 370 380 390 400 410
pF1KSD SFRRPFWREEHIEGGHSNTDRP-SRMIFYPPP---REGALLLASYTWSDAAAAFAG-LSR
:..::: : :. :. . ::: :. . . : . ...: .
NP_787 EFEEPFWGPECNSLQFVWEDEAESHTLTYPPELWYRKICGFDVLYPPERYGHVLSGWICG
320 330 340 350 360 370
420 430 440 450 460
pF1KSD EEALRLA-LDD--VAALHGPVVRQLWDGTGVVK-------RWAEDQHSQGGFVVQP--PA
:::: . :: :: . ..::. . .. : :. . . .:.. .
NP_787 EEALVMEKCDDEAVAEICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSS
380 390 400 410 420 430
470 480 490 500
pF1KSD LWQTEKDDWTVPYG--------RIYFAGE--HTAY---PHGWVETAVKSALRAAIKINSR
..:: .:: .. :.:: : : :: . .. . : :
NP_787 GADVEKLAKPLPYTESSKTAPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYRDL
440 450 460 470 480 490
510 520 530 540 550 560
pF1KSD KGPASDTASPEGHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
NP_787 FQQGT
500
567 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:54:00 2016 done: Thu Nov 3 08:54:01 2016
Total Scan time: 9.870 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]