Result of FASTA (omim) for
pFN21ASDB0004
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDB0004, 1086 aa
1>>>pF1KSDB0004 1086 - 1086 aa - 1086 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.3980+/-0.000411; mu= -4.6682+/- 0.026
mean_var=376.9155+/-78.258, 0's: 0 Z-trim(123.3): 78 B-trim: 844 in 1/56
Lambda= 0.066062
statistics sampled from 42789 (42876) to 42789 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.503), width: 16
Scan time: 17.610
The best scores are: opt bits E(85289)
NP_005623 (OMIM: 603267) calpain-15 [Homo sapiens] (1086) 7635 742.5 3e-213
XP_011520928 (OMIM: 603267) PREDICTED: calpain-15 (1154) 7635 742.5 3.2e-213
XP_011520934 (OMIM: 603267) PREDICTED: calpain-15 (1094) 7609 740.0 1.7e-212
XP_011520932 (OMIM: 603267) PREDICTED: calpain-15 (1094) 7609 740.0 1.7e-212
XP_011520933 (OMIM: 603267) PREDICTED: calpain-15 (1094) 7609 740.0 1.7e-212
XP_011520930 (OMIM: 603267) PREDICTED: calpain-15 (1094) 7609 740.0 1.7e-212
XP_011520931 (OMIM: 603267) PREDICTED: calpain-15 (1094) 7609 740.0 1.7e-212
XP_011520923 (OMIM: 603267) PREDICTED: calpain-15 (1162) 7609 740.1 1.8e-212
XP_016879085 (OMIM: 603267) PREDICTED: calpain-15 (1162) 7609 740.1 1.8e-212
XP_011520924 (OMIM: 603267) PREDICTED: calpain-15 (1162) 7609 740.1 1.8e-212
XP_011520925 (OMIM: 603267) PREDICTED: calpain-15 (1162) 7609 740.1 1.8e-212
XP_011520927 (OMIM: 603267) PREDICTED: calpain-15 (1162) 7609 740.1 1.8e-212
XP_011520922 (OMIM: 603267) PREDICTED: calpain-15 (1162) 7609 740.1 1.8e-212
XP_011520926 (OMIM: 603267) PREDICTED: calpain-15 (1162) 7609 740.1 1.8e-212
XP_011520929 (OMIM: 603267) PREDICTED: calpain-15 (1098) 7248 705.6 3.9e-202
XP_006715050 (OMIM: 604822) PREDICTED: calpain-11 ( 650) 560 68.0 2e-10
XP_006715048 (OMIM: 604822) PREDICTED: calpain-11 ( 724) 560 68.1 2.2e-10
NP_008989 (OMIM: 604822) calpain-11 [Homo sapiens] ( 739) 560 68.1 2.2e-10
XP_006715047 (OMIM: 604822) PREDICTED: calpain-11 ( 740) 560 68.1 2.2e-10
XP_011512577 (OMIM: 604822) PREDICTED: calpain-11 ( 743) 560 68.1 2.2e-10
XP_011512576 (OMIM: 604822) PREDICTED: calpain-11 ( 744) 560 68.1 2.2e-10
NP_775110 (OMIM: 114240,253600) calpain-3 isoform ( 729) 527 64.9 1.9e-09
XP_011542588 (OMIM: 114230) PREDICTED: calpain-2 c ( 447) 486 60.8 2e-08
NP_001185798 (OMIM: 114220,616907) calpain-1 catal ( 714) 488 61.2 2.5e-08
NP_005177 (OMIM: 114220,616907) calpain-1 catalyti ( 714) 488 61.2 2.5e-08
NP_001185797 (OMIM: 114220,616907) calpain-1 catal ( 714) 488 61.2 2.5e-08
XP_006718761 (OMIM: 114220,616907) PREDICTED: calp ( 714) 488 61.2 2.5e-08
XP_011543594 (OMIM: 114220,616907) PREDICTED: calp ( 714) 488 61.2 2.5e-08
NP_001739 (OMIM: 114230) calpain-2 catalytic subun ( 700) 486 61.0 2.8e-08
XP_016881854 (OMIM: 608839) PREDICTED: calpain-12 ( 503) 469 59.3 6.7e-08
XP_016881852 (OMIM: 608839) PREDICTED: calpain-12 ( 565) 469 59.3 7.3e-08
XP_016881851 (OMIM: 608839) PREDICTED: calpain-12 ( 590) 469 59.3 7.6e-08
XP_016881850 (OMIM: 608839) PREDICTED: calpain-12 ( 604) 469 59.3 7.7e-08
XP_016881849 (OMIM: 608839) PREDICTED: calpain-12 ( 652) 469 59.4 8.1e-08
XP_016881848 (OMIM: 608839) PREDICTED: calpain-12 ( 676) 469 59.4 8.4e-08
XP_016881847 (OMIM: 608839) PREDICTED: calpain-12 ( 698) 469 59.4 8.6e-08
XP_016881846 (OMIM: 608839) PREDICTED: calpain-12 ( 699) 469 59.4 8.6e-08
XP_016881845 (OMIM: 608839) PREDICTED: calpain-12 ( 702) 469 59.4 8.6e-08
NP_653292 (OMIM: 608839) calpain-12 [Homo sapiens] ( 719) 469 59.4 8.8e-08
XP_016881844 (OMIM: 608839) PREDICTED: calpain-12 ( 723) 469 59.4 8.8e-08
NP_075573 (OMIM: 601283,605286) calpain-10 isoform ( 517) 455 57.9 1.7e-07
NP_075571 (OMIM: 601283,605286) calpain-10 isoform ( 672) 455 58.0 2.1e-07
NP_006606 (OMIM: 606401) calpain-9 isoform 1 [Homo ( 690) 452 57.8 2.6e-07
XP_011542319 (OMIM: 606401) PREDICTED: calpain-9 i ( 721) 452 57.8 2.7e-07
NP_001139540 (OMIM: 114230) calpain-2 catalytic su ( 622) 418 54.5 2.3e-06
XP_011531465 (OMIM: 610228) PREDICTED: calpain-13 ( 433) 400 52.6 5.7e-06
XP_016860755 (OMIM: 610228) PREDICTED: calpain-13 ( 665) 400 52.8 7.9e-06
XP_016860754 (OMIM: 610228) PREDICTED: calpain-13 ( 669) 400 52.8 7.9e-06
XP_016860753 (OMIM: 610228) PREDICTED: calpain-13 ( 669) 400 52.8 7.9e-06
XP_011531462 (OMIM: 610228) PREDICTED: calpain-13 ( 669) 400 52.8 7.9e-06
>>NP_005623 (OMIM: 603267) calpain-15 [Homo sapiens] (1086 aa)
initn: 7635 init1: 7635 opt: 7635 Z-score: 3949.4 bits: 742.5 E(85289): 3e-213
Smith-Waterman score: 7635; 100.0% identity (100.0% similar) in 1086 aa overlap (1-1086:1-1086)
10 20 30 40 50 60
pF1KSD MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD DSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPPLTPEVAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPPLTPEVAGL
1030 1040 1050 1060 1070 1080
pF1KSD HGPRPL
::::::
NP_005 HGPRPL
>>XP_011520928 (OMIM: 603267) PREDICTED: calpain-15 isof (1154 aa)
initn: 7635 init1: 7635 opt: 7635 Z-score: 3949.0 bits: 742.5 E(85289): 3.2e-213
Smith-Waterman score: 7635; 100.0% identity (100.0% similar) in 1086 aa overlap (1-1086:69-1154)
10 20 30
pF1KSD MATVGEWSCVRCTFLNPAGQRQCSICEAPR
::::::::::::::::::::::::::::::
XP_011 GGPVWGGALVSRQHQPPRPRARSHTHSPGSMATVGEWSCVRCTFLNPAGQRQCSICEAPR
40 50 60 70 80 90
40 50 60 70 80 90
pF1KSD HKPDLNHILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPAPGAAFLPVLNGVLPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKPDLNHILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPAPGAAFLPVLNGVLPKP
100 110 120 130 140 150
100 110 120 130 140 150
pF1KSD PAILGEPKGSCQEEAGPVRTAGLVATEPARGQCEDKDEEEKEEQEEEEGAAEPRGGWACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAILGEPKGSCQEEAGPVRTAGLVATEPARGQCEDKDEEEKEEQEEEEGAAEPRGGWACP
160 170 180 190 200 210
160 170 180 190 200 210
pF1KSD RCTLHNTPVASSCSVCGGPRRLSLPRIPPEALVVPEVVAPAGFHVVPAAPPPGLPGEGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCTLHNTPVASSCSVCGGPRRLSLPRIPPEALVVPEVVAPAGFHVVPAAPPPGLPGEGAE
220 230 240 250 260 270
220 230 240 250 260 270
pF1KSD ANPPATSQGPAAEPEPPRVPPFSPFSSTLQNNPVPRSRREVPPQLQPPVPEAAQPSPSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANPPATSQGPAAEPEPPRVPPFSPFSSTLQNNPVPRSRREVPPQLQPPVPEAAQPSPSAG
280 290 300 310 320 330
280 290 300 310 320 330
pF1KSD CRGAPQGSGWAGASRLAELLSGKRLSVLEEEATEGGTSRVEAGSSTSGSDIIDLAGDTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRGAPQGSGWAGASRLAELLSGKRLSVLEEEATEGGTSRVEAGSSTSGSDIIDLAGDTVR
340 350 360 370 380 390
340 350 360 370 380 390
pF1KSD YTPASPSSPDFTTWSCAKCTLRNPTVAPRCSACGCSKLHGFQEHGEPPTHCPDCGADKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTPASPSSPDFTTWSCAKCTLRNPTVAPRCSACGCSKLHGFQEHGEPPTHCPDCGADKPS
400 410 420 430 440 450
400 410 420 430 440 450
pF1KSD PCGRSCGRVSSAQKAARVLPERPGQWACPACTLLNALRAKHCAACHTPQLLVAQRRGAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCGRSCGRVSSAQKAARVLPERPGQWACPACTLLNALRAKHCAACHTPQLLVAQRRGAAP
460 470 480 490 500 510
460 470 480 490 500 510
pF1KSD LRRRESMHVEQRRQTDEGEAKALWENIVAFCRENNVSFVDDSFPPGPESVGFPAGDSVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRRESMHVEQRRQTDEGEAKALWENIVAFCRENNVSFVDDSFPPGPESVGFPAGDSVQQ
520 530 540 550 560 570
520 530 540 550 560 570
pF1KSD RVRQWLRPQEINCSVFRDHRATWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVRQWLRPQEINCSVFRDHRATWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVER
580 590 600 610 620 630
580 590 600 610 620 630
pF1KSD VMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGCLLFSQAQRKQLWVALIEKALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGCLLFSQAQRKQLWVALIEKALA
640 650 660 670 680 690
640 650 660 670 680 690
pF1KSD KLHGSYFALQAGRAIEGLATLTGAPCESLALQLSSTNPREEPVDTDLIWAKMLSSKEAGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLHGSYFALQAGRAIEGLATLTGAPCESLALQLSSTNPREEPVDTDLIWAKMLSSKEAGF
700 710 720 730 740 750
700 710 720 730 740 750
pF1KSD LMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDVQGTRLLRLRNPWGRFSWNGSWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDVQGTRLLRLRNPWGRFSWNGSWSD
760 770 780 790 800 810
760 770 780 790 800 810
pF1KSD EWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQGCFPSSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQGCFPSSAS
820 830 840 850 860 870
820 830 840 850 860 870
pF1KSD APVGVTALTVLERASLEFALFQEGSRRSDAVDSHLLDLCILVFRATFGSGGHLSLGRLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APVGVTALTVLERASLEFALFQEGSRRSDAVDSHLLDLCILVFRATFGSGGHLSLGRLLA
880 890 900 910 920 930
880 890 900 910 920 930
pF1KSD HSKRAVKKFVSCDVMLEPGEYAVVCCAFNHWGPPLPGTPAPQASSPSAGVPRASPEPPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSKRAVKKFVSCDVMLEPGEYAVVCCAFNHWGPPLPGTPAPQASSPSAGVPRASPEPPGH
940 950 960 970 980 990
940 950 960 970 980 990
pF1KSD VLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVE
1000 1010 1020 1030 1040 1050
1000 1010 1020 1030 1040 1050
pF1KSD NRHPKAYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRHPKAYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLA
1060 1070 1080 1090 1100 1110
1060 1070 1080
pF1KSD HRKAAQAFLSDWTASKGTHSPPLTPEVAGLHGPRPL
::::::::::::::::::::::::::::::::::::
XP_011 HRKAAQAFLSDWTASKGTHSPPLTPEVAGLHGPRPL
1120 1130 1140 1150
>>XP_011520934 (OMIM: 603267) PREDICTED: calpain-15 isof (1094 aa)
initn: 7248 init1: 7248 opt: 7609 Z-score: 3936.0 bits: 740.0 E(85289): 1.7e-212
Smith-Waterman score: 7609; 99.3% identity (99.3% similar) in 1094 aa overlap (1-1086:1-1094)
10 20 30 40 50 60
pF1KSD MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KSD DSVPPLHR--------QVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPP
:::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSVPPLHRSSPVPSPRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPP
1030 1040 1050 1060 1070 1080
1080
pF1KSD LTPEVAGLHGPRPL
::::::::::::::
XP_011 LTPEVAGLHGPRPL
1090
>>XP_011520932 (OMIM: 603267) PREDICTED: calpain-15 isof (1094 aa)
initn: 7248 init1: 7248 opt: 7609 Z-score: 3936.0 bits: 740.0 E(85289): 1.7e-212
Smith-Waterman score: 7609; 99.3% identity (99.3% similar) in 1094 aa overlap (1-1086:1-1094)
10 20 30 40 50 60
pF1KSD MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KSD DSVPPLHR--------QVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPP
:::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSVPPLHRSSPVPSPRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPP
1030 1040 1050 1060 1070 1080
1080
pF1KSD LTPEVAGLHGPRPL
::::::::::::::
XP_011 LTPEVAGLHGPRPL
1090
>>XP_011520933 (OMIM: 603267) PREDICTED: calpain-15 isof (1094 aa)
initn: 7248 init1: 7248 opt: 7609 Z-score: 3936.0 bits: 740.0 E(85289): 1.7e-212
Smith-Waterman score: 7609; 99.3% identity (99.3% similar) in 1094 aa overlap (1-1086:1-1094)
10 20 30 40 50 60
pF1KSD MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KSD DSVPPLHR--------QVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPP
:::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSVPPLHRSSPVPSPRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPP
1030 1040 1050 1060 1070 1080
1080
pF1KSD LTPEVAGLHGPRPL
::::::::::::::
XP_011 LTPEVAGLHGPRPL
1090
>>XP_011520930 (OMIM: 603267) PREDICTED: calpain-15 isof (1094 aa)
initn: 7248 init1: 7248 opt: 7609 Z-score: 3936.0 bits: 740.0 E(85289): 1.7e-212
Smith-Waterman score: 7609; 99.3% identity (99.3% similar) in 1094 aa overlap (1-1086:1-1094)
10 20 30 40 50 60
pF1KSD MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KSD DSVPPLHR--------QVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPP
:::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSVPPLHRSSPVPSPRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPP
1030 1040 1050 1060 1070 1080
1080
pF1KSD LTPEVAGLHGPRPL
::::::::::::::
XP_011 LTPEVAGLHGPRPL
1090
>>XP_011520931 (OMIM: 603267) PREDICTED: calpain-15 isof (1094 aa)
initn: 7248 init1: 7248 opt: 7609 Z-score: 3936.0 bits: 740.0 E(85289): 1.7e-212
Smith-Waterman score: 7609; 99.3% identity (99.3% similar) in 1094 aa overlap (1-1086:1-1094)
10 20 30 40 50 60
pF1KSD MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQCEDKDEEEKEEQEEEEGAAEPRGGWACPRCTLHNTPVASSCSVCGGPRRLSLPRIPPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVVPEVVAPAGFHVVPAAPPPGLPGEGAEANPPATSQGPAAEPEPPRVPPFSPFSSTLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNPVPRSRREVPPQLQPPVPEAAQPSPSAGCRGAPQGSGWAGASRLAELLSGKRLSVLEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EATEGGTSRVEAGSSTSGSDIIDLAGDTVRYTPASPSSPDFTTWSCAKCTLRNPTVAPRC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SACGCSKLHGFQEHGEPPTHCPDCGADKPSPCGRSCGRVSSAQKAARVLPERPGQWACPA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTLLNALRAKHCAACHTPQLLVAQRRGAAPLRRRESMHVEQRRQTDEGEAKALWENIVAF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRENNVSFVDDSFPPGPESVGFPAGDSVQQRVRQWLRPQEINCSVFRDHRATWSVFHTLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLPCDEAGCLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQLSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDSAYESLGLRPRHAYS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILDVRDVQGTRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRGELMPHGSSEGVFWMEYGDF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRYFDSVDICKVHSDWQEARVQGCFPSSASAPVGVTALTVLERASLEFALFQEGSRRSDA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSHLLDLCILVFRATFGSGGHLSLGRLLAHSKRAVKKFVSCDVMLEPGEYAVVCCAFNH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WGPPLPGTPAPQASSPSAGVPRASPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKAYLHVQCDCTDSFNVVSTRGSLRTQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KSD DSVPPLHR--------QVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPP
:::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSVPPLHRSSPVPSPRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASKGTHSPP
1030 1040 1050 1060 1070 1080
1080
pF1KSD LTPEVAGLHGPRPL
::::::::::::::
XP_011 LTPEVAGLHGPRPL
1090
>>XP_011520923 (OMIM: 603267) PREDICTED: calpain-15 isof (1162 aa)
initn: 7248 init1: 7248 opt: 7609 Z-score: 3935.6 bits: 740.1 E(85289): 1.8e-212
Smith-Waterman score: 7609; 99.3% identity (99.3% similar) in 1094 aa overlap (1-1086:69-1162)
10 20 30
pF1KSD MATVGEWSCVRCTFLNPAGQRQCSICEAPR
::::::::::::::::::::::::::::::
XP_011 GGPVWGGALVSRQHQPPRPRARSHTHSPGSMATVGEWSCVRCTFLNPAGQRQCSICEAPR
40 50 60 70 80 90
40 50 60 70 80 90
pF1KSD HKPDLNHILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPAPGAAFLPVLNGVLPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKPDLNHILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPAPGAAFLPVLNGVLPKP
100 110 120 130 140 150
100 110 120 130 140 150
pF1KSD PAILGEPKGSCQEEAGPVRTAGLVATEPARGQCEDKDEEEKEEQEEEEGAAEPRGGWACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAILGEPKGSCQEEAGPVRTAGLVATEPARGQCEDKDEEEKEEQEEEEGAAEPRGGWACP
160 170 180 190 200 210
160 170 180 190 200 210
pF1KSD RCTLHNTPVASSCSVCGGPRRLSLPRIPPEALVVPEVVAPAGFHVVPAAPPPGLPGEGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCTLHNTPVASSCSVCGGPRRLSLPRIPPEALVVPEVVAPAGFHVVPAAPPPGLPGEGAE
220 230 240 250 260 270
220 230 240 250 260 270
pF1KSD ANPPATSQGPAAEPEPPRVPPFSPFSSTLQNNPVPRSRREVPPQLQPPVPEAAQPSPSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANPPATSQGPAAEPEPPRVPPFSPFSSTLQNNPVPRSRREVPPQLQPPVPEAAQPSPSAG
280 290 300 310 320 330
280 290 300 310 320 330
pF1KSD CRGAPQGSGWAGASRLAELLSGKRLSVLEEEATEGGTSRVEAGSSTSGSDIIDLAGDTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRGAPQGSGWAGASRLAELLSGKRLSVLEEEATEGGTSRVEAGSSTSGSDIIDLAGDTVR
340 350 360 370 380 390
340 350 360 370 380 390
pF1KSD YTPASPSSPDFTTWSCAKCTLRNPTVAPRCSACGCSKLHGFQEHGEPPTHCPDCGADKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTPASPSSPDFTTWSCAKCTLRNPTVAPRCSACGCSKLHGFQEHGEPPTHCPDCGADKPS
400 410 420 430 440 450
400 410 420 430 440 450
pF1KSD PCGRSCGRVSSAQKAARVLPERPGQWACPACTLLNALRAKHCAACHTPQLLVAQRRGAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCGRSCGRVSSAQKAARVLPERPGQWACPACTLLNALRAKHCAACHTPQLLVAQRRGAAP
460 470 480 490 500 510
460 470 480 490 500 510
pF1KSD LRRRESMHVEQRRQTDEGEAKALWENIVAFCRENNVSFVDDSFPPGPESVGFPAGDSVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRRESMHVEQRRQTDEGEAKALWENIVAFCRENNVSFVDDSFPPGPESVGFPAGDSVQQ
520 530 540 550 560 570
520 530 540 550 560 570
pF1KSD RVRQWLRPQEINCSVFRDHRATWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVRQWLRPQEINCSVFRDHRATWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVER
580 590 600 610 620 630
580 590 600 610 620 630
pF1KSD VMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGCLLFSQAQRKQLWVALIEKALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGCLLFSQAQRKQLWVALIEKALA
640 650 660 670 680 690
640 650 660 670 680 690
pF1KSD KLHGSYFALQAGRAIEGLATLTGAPCESLALQLSSTNPREEPVDTDLIWAKMLSSKEAGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLHGSYFALQAGRAIEGLATLTGAPCESLALQLSSTNPREEPVDTDLIWAKMLSSKEAGF
700 710 720 730 740 750
700 710 720 730 740 750
pF1KSD LMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDVQGTRLLRLRNPWGRFSWNGSWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDVQGTRLLRLRNPWGRFSWNGSWSD
760 770 780 790 800 810
760 770 780 790 800 810
pF1KSD EWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQGCFPSSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQGCFPSSAS
820 830 840 850 860 870
820 830 840 850 860 870
pF1KSD APVGVTALTVLERASLEFALFQEGSRRSDAVDSHLLDLCILVFRATFGSGGHLSLGRLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APVGVTALTVLERASLEFALFQEGSRRSDAVDSHLLDLCILVFRATFGSGGHLSLGRLLA
880 890 900 910 920 930
880 890 900 910 920 930
pF1KSD HSKRAVKKFVSCDVMLEPGEYAVVCCAFNHWGPPLPGTPAPQASSPSAGVPRASPEPPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSKRAVKKFVSCDVMLEPGEYAVVCCAFNHWGPPLPGTPAPQASSPSAGVPRASPEPPGH
940 950 960 970 980 990
940 950 960 970 980 990
pF1KSD VLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVE
1000 1010 1020 1030 1040 1050
1000 1010 1020 1030 1040
pF1KSD NRHPKAYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHR--------QVLVILSQLEGNAG
:::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_011 NRHPKAYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRSSPVPSPRQVLVILSQLEGNAG
1060 1070 1080 1090 1100 1110
1050 1060 1070 1080
pF1KSD FSITHRLAHRKAAQAFLSDWTASKGTHSPPLTPEVAGLHGPRPL
::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSITHRLAHRKAAQAFLSDWTASKGTHSPPLTPEVAGLHGPRPL
1120 1130 1140 1150 1160
>>XP_016879085 (OMIM: 603267) PREDICTED: calpain-15 isof (1162 aa)
initn: 7248 init1: 7248 opt: 7609 Z-score: 3935.6 bits: 740.1 E(85289): 1.8e-212
Smith-Waterman score: 7609; 99.3% identity (99.3% similar) in 1094 aa overlap (1-1086:69-1162)
10 20 30
pF1KSD MATVGEWSCVRCTFLNPAGQRQCSICEAPR
::::::::::::::::::::::::::::::
XP_016 GGPVWGGALVSRQHQPPRPRARSHTHSPGSMATVGEWSCVRCTFLNPAGQRQCSICEAPR
40 50 60 70 80 90
40 50 60 70 80 90
pF1KSD HKPDLNHILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPAPGAAFLPVLNGVLPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKPDLNHILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPAPGAAFLPVLNGVLPKP
100 110 120 130 140 150
100 110 120 130 140 150
pF1KSD PAILGEPKGSCQEEAGPVRTAGLVATEPARGQCEDKDEEEKEEQEEEEGAAEPRGGWACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAILGEPKGSCQEEAGPVRTAGLVATEPARGQCEDKDEEEKEEQEEEEGAAEPRGGWACP
160 170 180 190 200 210
160 170 180 190 200 210
pF1KSD RCTLHNTPVASSCSVCGGPRRLSLPRIPPEALVVPEVVAPAGFHVVPAAPPPGLPGEGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCTLHNTPVASSCSVCGGPRRLSLPRIPPEALVVPEVVAPAGFHVVPAAPPPGLPGEGAE
220 230 240 250 260 270
220 230 240 250 260 270
pF1KSD ANPPATSQGPAAEPEPPRVPPFSPFSSTLQNNPVPRSRREVPPQLQPPVPEAAQPSPSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANPPATSQGPAAEPEPPRVPPFSPFSSTLQNNPVPRSRREVPPQLQPPVPEAAQPSPSAG
280 290 300 310 320 330
280 290 300 310 320 330
pF1KSD CRGAPQGSGWAGASRLAELLSGKRLSVLEEEATEGGTSRVEAGSSTSGSDIIDLAGDTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRGAPQGSGWAGASRLAELLSGKRLSVLEEEATEGGTSRVEAGSSTSGSDIIDLAGDTVR
340 350 360 370 380 390
340 350 360 370 380 390
pF1KSD YTPASPSSPDFTTWSCAKCTLRNPTVAPRCSACGCSKLHGFQEHGEPPTHCPDCGADKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTPASPSSPDFTTWSCAKCTLRNPTVAPRCSACGCSKLHGFQEHGEPPTHCPDCGADKPS
400 410 420 430 440 450
400 410 420 430 440 450
pF1KSD PCGRSCGRVSSAQKAARVLPERPGQWACPACTLLNALRAKHCAACHTPQLLVAQRRGAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCGRSCGRVSSAQKAARVLPERPGQWACPACTLLNALRAKHCAACHTPQLLVAQRRGAAP
460 470 480 490 500 510
460 470 480 490 500 510
pF1KSD LRRRESMHVEQRRQTDEGEAKALWENIVAFCRENNVSFVDDSFPPGPESVGFPAGDSVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRRESMHVEQRRQTDEGEAKALWENIVAFCRENNVSFVDDSFPPGPESVGFPAGDSVQQ
520 530 540 550 560 570
520 530 540 550 560 570
pF1KSD RVRQWLRPQEINCSVFRDHRATWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVRQWLRPQEINCSVFRDHRATWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVER
580 590 600 610 620 630
580 590 600 610 620 630
pF1KSD VMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGCLLFSQAQRKQLWVALIEKALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGCLLFSQAQRKQLWVALIEKALA
640 650 660 670 680 690
640 650 660 670 680 690
pF1KSD KLHGSYFALQAGRAIEGLATLTGAPCESLALQLSSTNPREEPVDTDLIWAKMLSSKEAGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLHGSYFALQAGRAIEGLATLTGAPCESLALQLSSTNPREEPVDTDLIWAKMLSSKEAGF
700 710 720 730 740 750
700 710 720 730 740 750
pF1KSD LMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDVQGTRLLRLRNPWGRFSWNGSWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDVQGTRLLRLRNPWGRFSWNGSWSD
760 770 780 790 800 810
760 770 780 790 800 810
pF1KSD EWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQGCFPSSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQGCFPSSAS
820 830 840 850 860 870
820 830 840 850 860 870
pF1KSD APVGVTALTVLERASLEFALFQEGSRRSDAVDSHLLDLCILVFRATFGSGGHLSLGRLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APVGVTALTVLERASLEFALFQEGSRRSDAVDSHLLDLCILVFRATFGSGGHLSLGRLLA
880 890 900 910 920 930
880 890 900 910 920 930
pF1KSD HSKRAVKKFVSCDVMLEPGEYAVVCCAFNHWGPPLPGTPAPQASSPSAGVPRASPEPPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSKRAVKKFVSCDVMLEPGEYAVVCCAFNHWGPPLPGTPAPQASSPSAGVPRASPEPPGH
940 950 960 970 980 990
940 950 960 970 980 990
pF1KSD VLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVE
1000 1010 1020 1030 1040 1050
1000 1010 1020 1030 1040
pF1KSD NRHPKAYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHR--------QVLVILSQLEGNAG
:::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_016 NRHPKAYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRSSPVPSPRQVLVILSQLEGNAG
1060 1070 1080 1090 1100 1110
1050 1060 1070 1080
pF1KSD FSITHRLAHRKAAQAFLSDWTASKGTHSPPLTPEVAGLHGPRPL
::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSITHRLAHRKAAQAFLSDWTASKGTHSPPLTPEVAGLHGPRPL
1120 1130 1140 1150 1160
>>XP_011520924 (OMIM: 603267) PREDICTED: calpain-15 isof (1162 aa)
initn: 7248 init1: 7248 opt: 7609 Z-score: 3935.6 bits: 740.1 E(85289): 1.8e-212
Smith-Waterman score: 7609; 99.3% identity (99.3% similar) in 1094 aa overlap (1-1086:69-1162)
10 20 30
pF1KSD MATVGEWSCVRCTFLNPAGQRQCSICEAPR
::::::::::::::::::::::::::::::
XP_011 GGPVWGGALVSRQHQPPRPRARSHTHSPGSMATVGEWSCVRCTFLNPAGQRQCSICEAPR
40 50 60 70 80 90
40 50 60 70 80 90
pF1KSD HKPDLNHILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPAPGAAFLPVLNGVLPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKPDLNHILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPAPGAAFLPVLNGVLPKP
100 110 120 130 140 150
100 110 120 130 140 150
pF1KSD PAILGEPKGSCQEEAGPVRTAGLVATEPARGQCEDKDEEEKEEQEEEEGAAEPRGGWACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAILGEPKGSCQEEAGPVRTAGLVATEPARGQCEDKDEEEKEEQEEEEGAAEPRGGWACP
160 170 180 190 200 210
160 170 180 190 200 210
pF1KSD RCTLHNTPVASSCSVCGGPRRLSLPRIPPEALVVPEVVAPAGFHVVPAAPPPGLPGEGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCTLHNTPVASSCSVCGGPRRLSLPRIPPEALVVPEVVAPAGFHVVPAAPPPGLPGEGAE
220 230 240 250 260 270
220 230 240 250 260 270
pF1KSD ANPPATSQGPAAEPEPPRVPPFSPFSSTLQNNPVPRSRREVPPQLQPPVPEAAQPSPSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANPPATSQGPAAEPEPPRVPPFSPFSSTLQNNPVPRSRREVPPQLQPPVPEAAQPSPSAG
280 290 300 310 320 330
280 290 300 310 320 330
pF1KSD CRGAPQGSGWAGASRLAELLSGKRLSVLEEEATEGGTSRVEAGSSTSGSDIIDLAGDTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRGAPQGSGWAGASRLAELLSGKRLSVLEEEATEGGTSRVEAGSSTSGSDIIDLAGDTVR
340 350 360 370 380 390
340 350 360 370 380 390
pF1KSD YTPASPSSPDFTTWSCAKCTLRNPTVAPRCSACGCSKLHGFQEHGEPPTHCPDCGADKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTPASPSSPDFTTWSCAKCTLRNPTVAPRCSACGCSKLHGFQEHGEPPTHCPDCGADKPS
400 410 420 430 440 450
400 410 420 430 440 450
pF1KSD PCGRSCGRVSSAQKAARVLPERPGQWACPACTLLNALRAKHCAACHTPQLLVAQRRGAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCGRSCGRVSSAQKAARVLPERPGQWACPACTLLNALRAKHCAACHTPQLLVAQRRGAAP
460 470 480 490 500 510
460 470 480 490 500 510
pF1KSD LRRRESMHVEQRRQTDEGEAKALWENIVAFCRENNVSFVDDSFPPGPESVGFPAGDSVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRRESMHVEQRRQTDEGEAKALWENIVAFCRENNVSFVDDSFPPGPESVGFPAGDSVQQ
520 530 540 550 560 570
520 530 540 550 560 570
pF1KSD RVRQWLRPQEINCSVFRDHRATWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVRQWLRPQEINCSVFRDHRATWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVER
580 590 600 610 620 630
580 590 600 610 620 630
pF1KSD VMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGCLLFSQAQRKQLWVALIEKALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGCLLFSQAQRKQLWVALIEKALA
640 650 660 670 680 690
640 650 660 670 680 690
pF1KSD KLHGSYFALQAGRAIEGLATLTGAPCESLALQLSSTNPREEPVDTDLIWAKMLSSKEAGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLHGSYFALQAGRAIEGLATLTGAPCESLALQLSSTNPREEPVDTDLIWAKMLSSKEAGF
700 710 720 730 740 750
700 710 720 730 740 750
pF1KSD LMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDVQGTRLLRLRNPWGRFSWNGSWSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDVQGTRLLRLRNPWGRFSWNGSWSD
760 770 780 790 800 810
760 770 780 790 800 810
pF1KSD EWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQGCFPSSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQGCFPSSAS
820 830 840 850 860 870
820 830 840 850 860 870
pF1KSD APVGVTALTVLERASLEFALFQEGSRRSDAVDSHLLDLCILVFRATFGSGGHLSLGRLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APVGVTALTVLERASLEFALFQEGSRRSDAVDSHLLDLCILVFRATFGSGGHLSLGRLLA
880 890 900 910 920 930
880 890 900 910 920 930
pF1KSD HSKRAVKKFVSCDVMLEPGEYAVVCCAFNHWGPPLPGTPAPQASSPSAGVPRASPEPPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSKRAVKKFVSCDVMLEPGEYAVVCCAFNHWGPPLPGTPAPQASSPSAGVPRASPEPPGH
940 950 960 970 980 990
940 950 960 970 980 990
pF1KSD VLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVE
1000 1010 1020 1030 1040 1050
1000 1010 1020 1030 1040
pF1KSD NRHPKAYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHR--------QVLVILSQLEGNAG
:::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_011 NRHPKAYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRSSPVPSPRQVLVILSQLEGNAG
1060 1070 1080 1090 1100 1110
1050 1060 1070 1080
pF1KSD FSITHRLAHRKAAQAFLSDWTASKGTHSPPLTPEVAGLHGPRPL
::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSITHRLAHRKAAQAFLSDWTASKGTHSPPLTPEVAGLHGPRPL
1120 1130 1140 1150 1160
1086 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:02:46 2016 done: Thu Nov 3 08:02:49 2016
Total Scan time: 17.610 Total Display time: 0.580
Function used was FASTA [36.3.4 Apr, 2011]