Result of FASTA (omim) for
pFN21ASDA1960
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1960, 852 aa
1>>>pF1KSDA1960 852 - 852 aa - 852 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.7683+/-0.000339; mu= 2.2178+/- 0.021
mean_var=274.8605+/-56.895, 0's: 0 Z-trim(124.0): 55 B-trim: 1009 in 2/58
Lambda= 0.077360
statistics sampled from 44681 (44751) to 44681 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.525), width: 16
Scan time: 15.800
The best scores are: opt bits E(85289)
NP_001166171 (OMIM: 611179) protein Shroom1 isofor ( 852) 5833 664.6 5.2e-190
XP_005271942 (OMIM: 611179) PREDICTED: protein Shr ( 852) 5833 664.6 5.2e-190
XP_005271943 (OMIM: 611179) PREDICTED: protein Shr ( 852) 5833 664.6 5.2e-190
XP_011541469 (OMIM: 611179) PREDICTED: protein Shr ( 852) 5833 664.6 5.2e-190
NP_597713 (OMIM: 611179) protein Shroom1 isoform 2 ( 847) 5786 659.4 2e-188
XP_006714597 (OMIM: 611179) PREDICTED: protein Shr ( 490) 3217 372.5 2.7e-102
XP_005263222 (OMIM: 604570) PREDICTED: protein Shr (1820) 422 61.0 5.8e-08
XP_011530463 (OMIM: 604570) PREDICTED: protein Shr (1820) 422 61.0 5.8e-08
XP_005263221 (OMIM: 604570) PREDICTED: protein Shr (1820) 422 61.0 5.8e-08
XP_005263220 (OMIM: 604570) PREDICTED: protein Shr (1820) 422 61.0 5.8e-08
XP_011530462 (OMIM: 604570) PREDICTED: protein Shr (1871) 422 61.0 5.9e-08
XP_006714345 (OMIM: 604570) PREDICTED: protein Shr (1961) 422 61.0 6.1e-08
XP_016863978 (OMIM: 604570) PREDICTED: protein Shr (1961) 422 61.0 6.1e-08
XP_016863977 (OMIM: 604570) PREDICTED: protein Shr (1962) 422 61.0 6.1e-08
NP_065910 (OMIM: 604570) protein Shroom3 [Homo sap (1996) 422 61.0 6.2e-08
XP_011530460 (OMIM: 604570) PREDICTED: protein Shr (1997) 422 61.0 6.2e-08
XP_011530461 (OMIM: 604570) PREDICTED: protein Shr (1997) 422 61.0 6.2e-08
XP_011530459 (OMIM: 604570) PREDICTED: protein Shr (2002) 422 61.0 6.2e-08
XP_011543808 (OMIM: 300103) PREDICTED: protein Shr ( 451) 400 58.0 1.1e-07
NP_001307592 (OMIM: 300103) protein Shroom2 isofor ( 451) 400 58.0 1.1e-07
XP_016884982 (OMIM: 300103) PREDICTED: protein Shr ( 451) 400 58.0 1.1e-07
XP_016884981 (OMIM: 300103) PREDICTED: protein Shr ( 450) 391 57.0 2.2e-07
XP_016884983 (OMIM: 300103) PREDICTED: protein Shr ( 450) 391 57.0 2.2e-07
NP_001307593 (OMIM: 300103) protein Shroom2 isofor ( 450) 391 57.0 2.2e-07
NP_001640 (OMIM: 300103) protein Shroom2 isoform 1 (1616) 400 58.5 2.9e-07
XP_005274557 (OMIM: 300103) PREDICTED: protein Shr (1615) 391 57.5 5.8e-07
XP_016885175 (OMIM: 300434,300579) PREDICTED: prot (1373) 367 54.8 3.3e-06
XP_016885173 (OMIM: 300434,300579) PREDICTED: prot (1415) 367 54.8 3.4e-06
XP_016885172 (OMIM: 300434,300579) PREDICTED: prot (1486) 367 54.8 3.5e-06
NP_065768 (OMIM: 300434,300579) protein Shroom4 [H (1493) 367 54.8 3.5e-06
XP_016885171 (OMIM: 300434,300579) PREDICTED: prot (1531) 367 54.8 3.6e-06
>>NP_001166171 (OMIM: 611179) protein Shroom1 isoform 1 (852 aa)
initn: 5833 init1: 5833 opt: 5833 Z-score: 3532.3 bits: 664.6 E(85289): 5.2e-190
Smith-Waterman score: 5833; 100.0% identity (100.0% similar) in 852 aa overlap (1-852:1-852)
10 20 30 40 50 60
pF1KSD MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
790 800 810 820 830 840
850
pF1KSD PPVQPPFPLLLT
::::::::::::
NP_001 PPVQPPFPLLLT
850
>>XP_005271942 (OMIM: 611179) PREDICTED: protein Shroom1 (852 aa)
initn: 5833 init1: 5833 opt: 5833 Z-score: 3532.3 bits: 664.6 E(85289): 5.2e-190
Smith-Waterman score: 5833; 100.0% identity (100.0% similar) in 852 aa overlap (1-852:1-852)
10 20 30 40 50 60
pF1KSD MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
790 800 810 820 830 840
850
pF1KSD PPVQPPFPLLLT
::::::::::::
XP_005 PPVQPPFPLLLT
850
>>XP_005271943 (OMIM: 611179) PREDICTED: protein Shroom1 (852 aa)
initn: 5833 init1: 5833 opt: 5833 Z-score: 3532.3 bits: 664.6 E(85289): 5.2e-190
Smith-Waterman score: 5833; 100.0% identity (100.0% similar) in 852 aa overlap (1-852:1-852)
10 20 30 40 50 60
pF1KSD MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
790 800 810 820 830 840
850
pF1KSD PPVQPPFPLLLT
::::::::::::
XP_005 PPVQPPFPLLLT
850
>>XP_011541469 (OMIM: 611179) PREDICTED: protein Shroom1 (852 aa)
initn: 5833 init1: 5833 opt: 5833 Z-score: 3532.3 bits: 664.6 E(85289): 5.2e-190
Smith-Waterman score: 5833; 100.0% identity (100.0% similar) in 852 aa overlap (1-852:1-852)
10 20 30 40 50 60
pF1KSD MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
790 800 810 820 830 840
850
pF1KSD PPVQPPFPLLLT
::::::::::::
XP_011 PPVQPPFPLLLT
850
>>NP_597713 (OMIM: 611179) protein Shroom1 isoform 2 [Ho (847 aa)
initn: 5119 init1: 5119 opt: 5786 Z-score: 3503.9 bits: 659.4 E(85289): 2e-188
Smith-Waterman score: 5786; 99.4% identity (99.4% similar) in 852 aa overlap (1-852:1-847)
10 20 30 40 50 60
pF1KSD MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD SRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVARRERAVREVLVRA
:::::::::::::::::::::: :::::::::::::::::::::::::::::::::
NP_597 SRLARVRRALARAASDSDPDEQ-----RLRLLQRQEEDAKELKEHVARRERAVREVLVRA
730 740 750 760 770
790 800 810 820 830 840
pF1KSD LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 LPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTC
780 790 800 810 820 830
850
pF1KSD PPVQPPFPLLLT
::::::::::::
NP_597 PPVQPPFPLLLT
840
>>XP_006714597 (OMIM: 611179) PREDICTED: protein Shroom1 (490 aa)
initn: 3254 init1: 3216 opt: 3217 Z-score: 1957.6 bits: 372.5 E(85289): 2.7e-102
Smith-Waterman score: 3217; 98.9% identity (99.4% similar) in 468 aa overlap (1-468:1-466)
10 20 30 40 50 60
pF1KSD MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAEAAAQAAEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
:::::::::::::::::::::::::::::::::::::::: ..: ::
XP_006 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGS--LQRVTSSNLSQLMPWDFQ
430 440 450 460 470
490 500 510 520 530 540
pF1KSD TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
XP_006 AMILQVPLTILP
480 490
>>XP_005263222 (OMIM: 604570) PREDICTED: protein Shroom3 (1820 aa)
initn: 621 init1: 352 opt: 422 Z-score: 264.0 bits: 61.0 E(85289): 5.8e-08
Smith-Waterman score: 494; 23.1% identity (50.1% similar) in 888 aa overlap (5-843:948-1802)
10 20 30
pF1KSD MEALGPG---GDRASPASSTSSLDLWHLSMRADS
::. :. . ::: ::: :. : ..
XP_005 TGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREA
920 930 940 950 960 970
40 50 60 70 80
pF1KSD AYSSFSAASGGPEPRTQSP----GTDLLPYLDWDYVRVVWGGP-----GPAPPDAALCTS
. ..: :: .: : : : . . :: : : .
XP_005 TLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWG
980 990 1000 1010 1020 1030
90 100 110 120 130 140
pF1KSD PRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAAEPPSPPASRAAYR
: ...:.. . ..: . : . ...: : : . . . . . .. :
XP_005 ARAGKSMSAEDLLERSDVLAGPVHVRSRSSP---ATADKRQDVLLGQDSGFGLVKDPCY-
1040 1050 1060 1070 1080 1090
150 160 170 180 190 200
pF1KSD QRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARP-PATHPRSASLSHPGG-EGEPAR
: : : : . ..:. . : .: : . : :. :: . .
XP_005 --LAGPGSRSLSCSERGQEEM-LPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQA
1100 1110 1120 1130 1140 1150
210 220 230 240 250
pF1KSD SRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEA-CSSSGLPGPEPLE
::.: : : :::. : .. . : .: : . . ::..: : .::
XP_005 SRTPCP----RPPLAGTQGLVTDTRAAPLTPIGT---PLPSAIPSGYCSQDGQTGRQPLP
1160 1170 1180 1190 1200
260 270 280 290 300 310
pF1KSD FQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGE----VLGSW
::. :. . ::: : . .. . . : . ..:.: . . ..:
XP_005 PYTPAMM----HRSNGHTLTQPPGPRGCEGDGPEHG--VEEGTRKRVSLPQWPPPSRAKW
1210 1220 1230 1240 1250
320 330 340 350 360 370
pF1KSD GGSG--GTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVS
. .. ..: ...:. :. . : .: . .. . : : :.:. :.:
XP_005 AHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDT--PLGAP-STPGRISLRIS
1260 1270 1280 1290 1300 1310
380 390 400 410 420
pF1KSD ETCIVPAWLP--SLPDEVFLEE-------APLVR-MRSPPDPHASQGPPASVHASDQPYG
:. . . : . ::::... .: . . :: : :: : :.. :. .
XP_005 ESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETP--VYSMDD-FP
1320 1330 1340 1350 1360 1370
430 440 450 460 470
pF1KSD TGLGQRTGQVTVPTEYPLHECPG-------TAGADDCWQGVNGSVGISRPTSHTPTGTAN
. . .. . .: : :. : . . :. :: . .:. :. .
XP_005 PPPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKG
1380 1390 1400 1410 1420 1430
480 490 500 510 520 530
pF1KSD DNIPTIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPT
.. . :. .... :. : .:.: .. .:: . . : . .: . .. : . .
XP_005 SEAESTPPSFMSVHAQLAG-SLGGQPAPIQTQSLSHDPVSG---TQGLEKKVS-PDPQKS
1440 1450 1460 1470 1480
540 550 560 570 580
pF1KSD WPSQCLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIP-----LAEV---RAAMRP
. : :..:... : :: : : . . . :..::.: : : : :..
XP_005 SEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQR
1490 1500 1510 1520 1530 1540
590 600 610 620 630 640
pF1KSD ACGEAGEEAASTFEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQ
. . .: :. . . . :. :: . . . . ..: . . ...
XP_005 TVSSSGCEGKRNEDKEAV--SMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVN
1550 1560 1570 1580 1590 1600
650 660 670 680 690 700
pF1KSD GKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMAD
::.:: . : . :. :. . : . . .:: . . : :.:.... :..:
XP_005 EKKAELIGSLTHKLETLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGD
1610 1620 1630 1640 1650 1660
710 720 730 740 750 760
pF1KSD LERVLGLLLLLGSRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVAR
:..:..::: :..:::::. .:. . :.. .:..:: .. ..: :.:::.::::.. :
XP_005 LDKVVNLLLSLSGRLARVENVLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDR
1670 1680 1690 1700 1710 1720
770 780 790 800 810 820
pF1KSD RERAVREVLVRALPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDL-GHH
:::.: .:. : :.:. : .. :...: .::.::..:.: :.:. . ..: .
XP_005 RERVVLGILANYLSEEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESLPSDF
1730 1740 1750 1760 1770 1780
830 840 850
pF1KSD APSPSP-ARPPG-TCPPVQPPFPLLLT
:. . : ::. : :.
XP_005 IPKAGALALPPNLTSEPIPAGGCTFSGIFPTLTSPL
1790 1800 1810 1820
>>XP_011530463 (OMIM: 604570) PREDICTED: protein Shroom3 (1820 aa)
initn: 621 init1: 352 opt: 422 Z-score: 264.0 bits: 61.0 E(85289): 5.8e-08
Smith-Waterman score: 494; 23.1% identity (50.1% similar) in 888 aa overlap (5-843:948-1802)
10 20 30
pF1KSD MEALGPG---GDRASPASSTSSLDLWHLSMRADS
::. :. . ::: ::: :. : ..
XP_011 TGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREA
920 930 940 950 960 970
40 50 60 70 80
pF1KSD AYSSFSAASGGPEPRTQSP----GTDLLPYLDWDYVRVVWGGP-----GPAPPDAALCTS
. ..: :: .: : : : . . :: : : .
XP_011 TLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWG
980 990 1000 1010 1020 1030
90 100 110 120 130 140
pF1KSD PRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAAEPPSPPASRAAYR
: ...:.. . ..: . : . ...: : : . . . . . .. :
XP_011 ARAGKSMSAEDLLERSDVLAGPVHVRSRSSP---ATADKRQDVLLGQDSGFGLVKDPCY-
1040 1050 1060 1070 1080 1090
150 160 170 180 190 200
pF1KSD QRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARP-PATHPRSASLSHPGG-EGEPAR
: : : : . ..:. . : .: : . : :. :: . .
XP_011 --LAGPGSRSLSCSERGQEEM-LPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQA
1100 1110 1120 1130 1140 1150
210 220 230 240 250
pF1KSD SRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEA-CSSSGLPGPEPLE
::.: : : :::. : .. . : .: : . . ::..: : .::
XP_011 SRTPCP----RPPLAGTQGLVTDTRAAPLTPIGT---PLPSAIPSGYCSQDGQTGRQPLP
1160 1170 1180 1190 1200
260 270 280 290 300 310
pF1KSD FQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGE----VLGSW
::. :. . ::: : . .. . . : . ..:.: . . ..:
XP_011 PYTPAMM----HRSNGHTLTQPPGPRGCEGDGPEHG--VEEGTRKRVSLPQWPPPSRAKW
1210 1220 1230 1240 1250
320 330 340 350 360 370
pF1KSD GGSG--GTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVS
. .. ..: ...:. :. . : .: . .. . : : :.:. :.:
XP_011 AHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDT--PLGAP-STPGRISLRIS
1260 1270 1280 1290 1300 1310
380 390 400 410 420
pF1KSD ETCIVPAWLP--SLPDEVFLEE-------APLVR-MRSPPDPHASQGPPASVHASDQPYG
:. . . : . ::::... .: . . :: : :: : :.. :. .
XP_011 ESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETP--VYSMDD-FP
1320 1330 1340 1350 1360 1370
430 440 450 460 470
pF1KSD TGLGQRTGQVTVPTEYPLHECPG-------TAGADDCWQGVNGSVGISRPTSHTPTGTAN
. . .. . .: : :. : . . :. :: . .:. :. .
XP_011 PPPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKG
1380 1390 1400 1410 1420 1430
480 490 500 510 520 530
pF1KSD DNIPTIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPT
.. . :. .... :. : .:.: .. .:: . . : . .: . .. : . .
XP_011 SEAESTPPSFMSVHAQLAG-SLGGQPAPIQTQSLSHDPVSG---TQGLEKKVS-PDPQKS
1440 1450 1460 1470 1480
540 550 560 570 580
pF1KSD WPSQCLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIP-----LAEV---RAAMRP
. : :..:... : :: : : . . . :..::.: : : : :..
XP_011 SEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQR
1490 1500 1510 1520 1530 1540
590 600 610 620 630 640
pF1KSD ACGEAGEEAASTFEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQ
. . .: :. . . . :. :: . . . . ..: . . ...
XP_011 TVSSSGCEGKRNEDKEAV--SMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVN
1550 1560 1570 1580 1590 1600
650 660 670 680 690 700
pF1KSD GKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMAD
::.:: . : . :. :. . : . . .:: . . : :.:.... :..:
XP_011 EKKAELIGSLTHKLETLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGD
1610 1620 1630 1640 1650 1660
710 720 730 740 750 760
pF1KSD LERVLGLLLLLGSRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVAR
:..:..::: :..:::::. .:. . :.. .:..:: .. ..: :.:::.::::.. :
XP_011 LDKVVNLLLSLSGRLARVENVLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDR
1670 1680 1690 1700 1710 1720
770 780 790 800 810 820
pF1KSD RERAVREVLVRALPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDL-GHH
:::.: .:. : :.:. : .. :...: .::.::..:.: :.:. . ..: .
XP_011 RERVVLGILANYLSEEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESLPSDF
1730 1740 1750 1760 1770 1780
830 840 850
pF1KSD APSPSP-ARPPG-TCPPVQPPFPLLLT
:. . : ::. : :.
XP_011 IPKAGALALPPNLTSEPIPAGGCTFSGIFPTLTSPL
1790 1800 1810 1820
>>XP_005263221 (OMIM: 604570) PREDICTED: protein Shroom3 (1820 aa)
initn: 621 init1: 352 opt: 422 Z-score: 264.0 bits: 61.0 E(85289): 5.8e-08
Smith-Waterman score: 494; 23.1% identity (50.1% similar) in 888 aa overlap (5-843:948-1802)
10 20 30
pF1KSD MEALGPG---GDRASPASSTSSLDLWHLSMRADS
::. :. . ::: ::: :. : ..
XP_005 TGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREA
920 930 940 950 960 970
40 50 60 70 80
pF1KSD AYSSFSAASGGPEPRTQSP----GTDLLPYLDWDYVRVVWGGP-----GPAPPDAALCTS
. ..: :: .: : : : . . :: : : .
XP_005 TLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWG
980 990 1000 1010 1020 1030
90 100 110 120 130 140
pF1KSD PRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAAEPPSPPASRAAYR
: ...:.. . ..: . : . ...: : : . . . . . .. :
XP_005 ARAGKSMSAEDLLERSDVLAGPVHVRSRSSP---ATADKRQDVLLGQDSGFGLVKDPCY-
1040 1050 1060 1070 1080 1090
150 160 170 180 190 200
pF1KSD QRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARP-PATHPRSASLSHPGG-EGEPAR
: : : : . ..:. . : .: : . : :. :: . .
XP_005 --LAGPGSRSLSCSERGQEEM-LPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQA
1100 1110 1120 1130 1140 1150
210 220 230 240 250
pF1KSD SRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEA-CSSSGLPGPEPLE
::.: : : :::. : .. . : .: : . . ::..: : .::
XP_005 SRTPCP----RPPLAGTQGLVTDTRAAPLTPIGT---PLPSAIPSGYCSQDGQTGRQPLP
1160 1170 1180 1190 1200
260 270 280 290 300 310
pF1KSD FQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGE----VLGSW
::. :. . ::: : . .. . . : . ..:.: . . ..:
XP_005 PYTPAMM----HRSNGHTLTQPPGPRGCEGDGPEHG--VEEGTRKRVSLPQWPPPSRAKW
1210 1220 1230 1240 1250
320 330 340 350 360 370
pF1KSD GGSG--GTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVS
. .. ..: ...:. :. . : .: . .. . : : :.:. :.:
XP_005 AHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDT--PLGAP-STPGRISLRIS
1260 1270 1280 1290 1300 1310
380 390 400 410 420
pF1KSD ETCIVPAWLP--SLPDEVFLEE-------APLVR-MRSPPDPHASQGPPASVHASDQPYG
:. . . : . ::::... .: . . :: : :: : :.. :. .
XP_005 ESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETP--VYSMDD-FP
1320 1330 1340 1350 1360 1370
430 440 450 460 470
pF1KSD TGLGQRTGQVTVPTEYPLHECPG-------TAGADDCWQGVNGSVGISRPTSHTPTGTAN
. . .. . .: : :. : . . :. :: . .:. :. .
XP_005 PPPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKG
1380 1390 1400 1410 1420 1430
480 490 500 510 520 530
pF1KSD DNIPTIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPT
.. . :. .... :. : .:.: .. .:: . . : . .: . .. : . .
XP_005 SEAESTPPSFMSVHAQLAG-SLGGQPAPIQTQSLSHDPVSG---TQGLEKKVS-PDPQKS
1440 1450 1460 1470 1480
540 550 560 570 580
pF1KSD WPSQCLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIP-----LAEV---RAAMRP
. : :..:... : :: : : . . . :..::.: : : : :..
XP_005 SEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQR
1490 1500 1510 1520 1530 1540
590 600 610 620 630 640
pF1KSD ACGEAGEEAASTFEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQ
. . .: :. . . . :. :: . . . . ..: . . ...
XP_005 TVSSSGCEGKRNEDKEAV--SMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVN
1550 1560 1570 1580 1590 1600
650 660 670 680 690 700
pF1KSD GKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMAD
::.:: . : . :. :. . : . . .:: . . : :.:.... :..:
XP_005 EKKAELIGSLTHKLETLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGD
1610 1620 1630 1640 1650 1660
710 720 730 740 750 760
pF1KSD LERVLGLLLLLGSRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVAR
:..:..::: :..:::::. .:. . :.. .:..:: .. ..: :.:::.::::.. :
XP_005 LDKVVNLLLSLSGRLARVENVLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDR
1670 1680 1690 1700 1710 1720
770 780 790 800 810 820
pF1KSD RERAVREVLVRALPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDL-GHH
:::.: .:. : :.:. : .. :...: .::.::..:.: :.:. . ..: .
XP_005 RERVVLGILANYLSEEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESLPSDF
1730 1740 1750 1760 1770 1780
830 840 850
pF1KSD APSPSP-ARPPG-TCPPVQPPFPLLLT
:. . : ::. : :.
XP_005 IPKAGALALPPNLTSEPIPAGGCTFSGIFPTLTSPL
1790 1800 1810 1820
>>XP_005263220 (OMIM: 604570) PREDICTED: protein Shroom3 (1820 aa)
initn: 621 init1: 352 opt: 422 Z-score: 264.0 bits: 61.0 E(85289): 5.8e-08
Smith-Waterman score: 494; 23.1% identity (50.1% similar) in 888 aa overlap (5-843:948-1802)
10 20 30
pF1KSD MEALGPG---GDRASPASSTSSLDLWHLSMRADS
::. :. . ::: ::: :. : ..
XP_005 TGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREA
920 930 940 950 960 970
40 50 60 70 80
pF1KSD AYSSFSAASGGPEPRTQSP----GTDLLPYLDWDYVRVVWGGP-----GPAPPDAALCTS
. ..: :: .: : : : . . :: : : .
XP_005 TLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWG
980 990 1000 1010 1020 1030
90 100 110 120 130 140
pF1KSD PRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAAEPPSPPASRAAYR
: ...:.. . ..: . : . ...: : : . . . . . .. :
XP_005 ARAGKSMSAEDLLERSDVLAGPVHVRSRSSP---ATADKRQDVLLGQDSGFGLVKDPCY-
1040 1050 1060 1070 1080 1090
150 160 170 180 190 200
pF1KSD QRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARP-PATHPRSASLSHPGG-EGEPAR
: : : : . ..:. . : .: : . : :. :: . .
XP_005 --LAGPGSRSLSCSERGQEEM-LPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQA
1100 1110 1120 1130 1140 1150
210 220 230 240 250
pF1KSD SRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEA-CSSSGLPGPEPLE
::.: : : :::. : .. . : .: : . . ::..: : .::
XP_005 SRTPCP----RPPLAGTQGLVTDTRAAPLTPIGT---PLPSAIPSGYCSQDGQTGRQPLP
1160 1170 1180 1190 1200
260 270 280 290 300 310
pF1KSD FQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGE----VLGSW
::. :. . ::: : . .. . . : . ..:.: . . ..:
XP_005 PYTPAMM----HRSNGHTLTQPPGPRGCEGDGPEHG--VEEGTRKRVSLPQWPPPSRAKW
1210 1220 1230 1240 1250
320 330 340 350 360 370
pF1KSD GGSG--GTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVS
. .. ..: ...:. :. . : .: . .. . : : :.:. :.:
XP_005 AHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDT--PLGAP-STPGRISLRIS
1260 1270 1280 1290 1300 1310
380 390 400 410 420
pF1KSD ETCIVPAWLP--SLPDEVFLEE-------APLVR-MRSPPDPHASQGPPASVHASDQPYG
:. . . : . ::::... .: . . :: : :: : :.. :. .
XP_005 ESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETP--VYSMDD-FP
1320 1330 1340 1350 1360 1370
430 440 450 460 470
pF1KSD TGLGQRTGQVTVPTEYPLHECPG-------TAGADDCWQGVNGSVGISRPTSHTPTGTAN
. . .. . .: : :. : . . :. :: . .:. :. .
XP_005 PPPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKG
1380 1390 1400 1410 1420 1430
480 490 500 510 520 530
pF1KSD DNIPTIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPT
.. . :. .... :. : .:.: .. .:: . . : . .: . .. : . .
XP_005 SEAESTPPSFMSVHAQLAG-SLGGQPAPIQTQSLSHDPVSG---TQGLEKKVS-PDPQKS
1440 1450 1460 1470 1480
540 550 560 570 580
pF1KSD WPSQCLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIP-----LAEV---RAAMRP
. : :..:... : :: : : . . . :..::.: : : : :..
XP_005 SEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQR
1490 1500 1510 1520 1530 1540
590 600 610 620 630 640
pF1KSD ACGEAGEEAASTFEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQ
. . .: :. . . . :. :: . . . . ..: . . ...
XP_005 TVSSSGCEGKRNEDKEAV--SMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVN
1550 1560 1570 1580 1590 1600
650 660 670 680 690 700
pF1KSD GKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMAD
::.:: . : . :. :. . : . . .:: . . : :.:.... :..:
XP_005 EKKAELIGSLTHKLETLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGD
1610 1620 1630 1640 1650 1660
710 720 730 740 750 760
pF1KSD LERVLGLLLLLGSRLARVRRALARAASDSDPDEQASLLQRLRLLQRQEEDAKELKEHVAR
:..:..::: :..:::::. .:. . :.. .:..:: .. ..: :.:::.::::.. :
XP_005 LDKVVNLLLSLSGRLARVENVLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDR
1670 1680 1690 1700 1710 1720
770 780 790 800 810 820
pF1KSD RERAVREVLVRALPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDL-GHH
:::.: .:. : :.:. : .. :...: .::.::..:.: :.:. . ..: .
XP_005 RERVVLGILANYLSEEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESLPSDF
1730 1740 1750 1760 1770 1780
830 840 850
pF1KSD APSPSP-ARPPG-TCPPVQPPFPLLLT
:. . : ::. : :.
XP_005 IPKAGALALPPNLTSEPIPAGGCTFSGIFPTLTSPL
1790 1800 1810 1820
852 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 07:49:54 2016 done: Thu Nov 3 07:49:56 2016
Total Scan time: 15.800 Total Display time: 0.260
Function used was FASTA [36.3.4 Apr, 2011]