Result of FASTA (omim) for
pFN21ASDA1830
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1830, 454 aa
1>>>pF1KSDA1830 454 - 454 aa - 454 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4399+/-0.000392; mu= 17.3547+/- 0.024
mean_var=68.0044+/-14.174, 0's: 0 Z-trim(110.8): 37 B-trim: 944 in 1/51
Lambda= 0.155527
statistics sampled from 19251 (19288) to 19251 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.585), E-opt: 0.2 (0.226), width: 16
Scan time: 8.800
The best scores are: opt bits E(85289)
NP_061895 (OMIM: 616102) protein disulfide-isomera ( 454) 3012 685.1 1e-196
XP_011524335 (OMIM: 616102) PREDICTED: protein dis ( 313) 2037 466.2 5.4e-131
XP_005266771 (OMIM: 616102) PREDICTED: protein dis ( 313) 2037 466.2 5.4e-131
XP_011524337 (OMIM: 616102) PREDICTED: protein dis ( 229) 1443 332.9 5.5e-91
XP_011524336 (OMIM: 616102) PREDICTED: protein dis ( 231) 1441 332.4 7.5e-91
NP_000909 (OMIM: 112240,176790) protein disulfide- ( 508) 320 81.1 7.6e-15
NP_005304 (OMIM: 602046) protein disulfide-isomera ( 505) 299 76.4 2e-13
XP_011508610 (OMIM: 611099) PREDICTED: protein dis ( 402) 282 72.5 2.3e-12
NP_001269636 (OMIM: 611099) protein disulfide-isom ( 437) 282 72.5 2.5e-12
NP_005733 (OMIM: 611099) protein disulfide-isomera ( 440) 282 72.5 2.5e-12
NP_001269635 (OMIM: 611099) protein disulfide-isom ( 445) 282 72.5 2.5e-12
NP_001269634 (OMIM: 611099) protein disulfide-isom ( 488) 282 72.6 2.7e-12
NP_001269633 (OMIM: 611099) protein disulfide-isom ( 492) 282 72.6 2.7e-12
NP_001139021 (OMIM: 616412) thioredoxin domain-con ( 324) 242 63.5 9.7e-10
NP_110437 (OMIM: 616412) thioredoxin domain-contai ( 432) 242 63.6 1.2e-09
NP_110382 (OMIM: 610527) thioredoxin-related trans ( 280) 227 60.1 8.8e-09
NP_006840 (OMIM: 608012) protein disulfide-isomera ( 525) 223 59.3 2.8e-08
NP_001258510 (OMIM: 607987) dnaJ homolog subfamily ( 747) 201 54.5 1.2e-06
NP_061854 (OMIM: 607987) dnaJ homolog subfamily C ( 793) 201 54.5 1.2e-06
NP_006801 (OMIM: 616942) protein disulfide-isomera ( 519) 196 53.3 1.8e-06
NP_001004128 (OMIM: 603120) sulfhydryl oxidase 1 i ( 604) 176 48.8 4.7e-05
NP_002817 (OMIM: 603120) sulfhydryl oxidase 1 isof ( 747) 176 48.9 5.6e-05
NP_055866 (OMIM: 609170) endoplasmic reticulum res ( 406) 170 47.4 8.5e-05
NP_859052 (OMIM: 612860) sulfhydryl oxidase 2 prec ( 698) 171 47.7 0.00012
NP_001222 (OMIM: 114250,616231) calsequestrin-1 pr ( 396) 166 46.5 0.00016
NP_036605 (OMIM: 609063,616811) thioredoxin, mitoc ( 166) 156 44.0 0.00035
XP_006724289 (OMIM: 609063,616811) PREDICTED: thio ( 166) 156 44.0 0.00035
NP_066979 (OMIM: 616766) thioredoxin-related trans ( 349) 160 45.1 0.00036
XP_005261565 (OMIM: 609063,616811) PREDICTED: thio ( 197) 156 44.1 0.00041
NP_001223 (OMIM: 114251,604772,611938) calsequestr ( 399) 147 42.2 0.003
>>NP_061895 (OMIM: 616102) protein disulfide-isomerase T (454 aa)
initn: 3012 init1: 3012 opt: 3012 Z-score: 3652.7 bits: 685.1 E(85289): 1e-196
Smith-Waterman score: 3012; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)
10 20 30 40 50 60
pF1KSD MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD MDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDSILQRLKRIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDSILQRLKRIV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD FDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSENENQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSENENQ
370 380 390 400 410 420
430 440 450
pF1KSD EQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
::::::::::::::::::::::::::::::::::
NP_061 EQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
430 440 450
>>XP_011524335 (OMIM: 616102) PREDICTED: protein disulfi (313 aa)
initn: 2037 init1: 2037 opt: 2037 Z-score: 2472.8 bits: 466.2 E(85289): 5.4e-131
Smith-Waterman score: 2037; 100.0% identity (100.0% similar) in 313 aa overlap (142-454:1-313)
120 130 140 150 160 170
pF1KSD NYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAA
::::::::::::::::::::::::::::::
XP_011 MFEHMQKRHRVFFVYVGGESPLKEKYIDAA
10 20 30
180 190 200 210 220 230
pF1KSD SELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNY
40 50 60 70 80 90
240 250 260 270 280 290
pF1KSD LAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMD
100 110 120 130 140 150
300 310 320 330 340 350
pF1KSD GNDYINTLLMDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNDYINTLLMDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDS
160 170 180 190 200 210
360 370 380 390 400 410
pF1KSD ILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYE
220 230 240 250 260 270
420 430 440 450
pF1KSD VSKSENENQEQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
:::::::::::::::::::::::::::::::::::::::::::
XP_011 VSKSENENQEQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
280 290 300 310
>>XP_005266771 (OMIM: 616102) PREDICTED: protein disulfi (313 aa)
initn: 2037 init1: 2037 opt: 2037 Z-score: 2472.8 bits: 466.2 E(85289): 5.4e-131
Smith-Waterman score: 2037; 100.0% identity (100.0% similar) in 313 aa overlap (142-454:1-313)
120 130 140 150 160 170
pF1KSD NYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAA
::::::::::::::::::::::::::::::
XP_005 MFEHMQKRHRVFFVYVGGESPLKEKYIDAA
10 20 30
180 190 200 210 220 230
pF1KSD SELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELIVYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNY
40 50 60 70 80 90
240 250 260 270 280 290
pF1KSD LAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMD
100 110 120 130 140 150
300 310 320 330 340 350
pF1KSD GNDYINTLLMDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNDYINTLLMDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDS
160 170 180 190 200 210
360 370 380 390 400 410
pF1KSD ILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYE
220 230 240 250 260 270
420 430 440 450
pF1KSD VSKSENENQEQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
:::::::::::::::::::::::::::::::::::::::::::
XP_005 VSKSENENQEQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
280 290 300 310
>>XP_011524337 (OMIM: 616102) PREDICTED: protein disulfi (229 aa)
initn: 1461 init1: 1440 opt: 1443 Z-score: 1754.5 bits: 332.9 E(85289): 5.5e-91
Smith-Waterman score: 1443; 93.9% identity (96.9% similar) in 228 aa overlap (1-228:1-225)
10 20 30 40 50 60
pF1KSD MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLY
:::::::::::::::::::::::::::::::: :.. . .. .:.
XP_011 FSASEEVVPEYVTLKEMPAVLVFKDETYFVYD---DNNYTLMLSYKRYYLHT
190 200 210 220
250 260 270 280 290 300
pF1KSD ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLL
>>XP_011524336 (OMIM: 616102) PREDICTED: protein disulfi (231 aa)
initn: 1462 init1: 1441 opt: 1441 Z-score: 1752.1 bits: 332.4 E(85289): 7.5e-91
Smith-Waterman score: 1441; 99.1% identity (99.5% similar) in 214 aa overlap (1-214:1-214)
10 20 30 40 50 60
pF1KSD MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLY
:::::::::::::::::::::::::::::::: .
XP_011 FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDAFILDSESTCAGLLHGCIG
190 200 210 220 230
250 260 270 280 290 300
pF1KSD ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLL
>>NP_000909 (OMIM: 112240,176790) protein disulfide-isom (508 aa)
initn: 288 init1: 249 opt: 320 Z-score: 387.5 bits: 81.1 E(85289): 7.6e-15
Smith-Waterman score: 320; 31.3% identity (63.6% similar) in 195 aa overlap (45-232:45-229)
20 30 40 50 60 70
pF1KSD TVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIG
::.:::::::::: : : . ... ..:. :
NP_000 VRADAPEEEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEG
20 30 40 50 60 70
80 90 100 110 120 130
pF1KSD SPVKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLAY--NYRGPRTKDDIIEFAHRVSG
: ....:.::: :..:...:::::::::... :: : .: . : :::... .. .:
NP_000 SEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTG
80 90 100 110 120 130
140 150 160 170 180
pF1KSD ALIRPLPSQQMFEHMQKRHRV----FFVYVGGESPLKEKYIDAASELIVYTYFFSASEEV
::. : . . .: :: : :: .....:: . . .... .:
NP_000 PAATTLPDGAAAESLVESSEVAVIGFFKDV--ESDSAKQFLQAAEAIDDIPFGITSNSDV
140 150 160 170 180 190
190 200 210 220 230 240
pF1KSD VPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLYELGDTGK
.: :. .:..:: .:: .. .. . ...: . ...
NP_000 FSKYQLDKD--GVVLFKK-----FDEGRN-NFEGEVTKENLLDFIKHNQLPLVIEFTEQT
200 210 220 230 240
250 260 270 280 290 300
pF1KSD LVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLLMDELTVP
NP_000 APKIFGGEIKTHILLFLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEF
250 260 270 280 290 300
>--
initn: 178 init1: 154 opt: 216 Z-score: 261.4 bits: 57.8 E(85289): 8.1e-08
Smith-Waterman score: 216; 37.0% identity (67.6% similar) in 108 aa overlap (21-125:371-469)
10 20 30 40 50
pF1KSD MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYA
..: :.: ::. .: :..: .:.:::
NP_000 EFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNF-EDV--AFDEKKN---VFVEFYA
350 360 370 380 390
60 70 80 90 100
pF1KSD PWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGD--
:::::::.: :::...: .:. . ..:::.:. : . :...::.:.. ..
NP_000 PWCGHCKQLAPIWDKLGETYKD-HENIVIAKMDSTANEVEAVK--VHSFPTLKFFPASAD
400 410 420 430 440 450
110 120 130 140 150 160
pF1KSD -LAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKY
. .: : :: : . .:
NP_000 RTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL
460 470 480 490 500
>>NP_005304 (OMIM: 602046) protein disulfide-isomerase A (505 aa)
initn: 229 init1: 134 opt: 299 Z-score: 362.1 bits: 76.4 E(85289): 2e-13
Smith-Waterman score: 339; 24.7% identity (59.3% similar) in 344 aa overlap (28-345:28-362)
10 20 30 40 50
pF1KSD MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDD-----IWLVDFYAPWCGH
.: :..: :.: .: . ::.:.::::::
NP_005 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNF-ESRISDTGSAGLMLVEFFAPWCGH
10 20 30 40 50
60 70 80 90 100 110
pF1KSD CKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLAYNYR
::.: : .. .. ..:.: : ..:.: :. .. ...:: ::::.:... :. : :
NP_005 CKRLAPEYEAAATRLKGI---VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD GPRTKDDIIEFAHRVSGALIRPLPSQQMFEHM--QKRHRVFFVYVGGESPLKEKYIDAAS
:::: : :. .. .: :: ... :... .: . . . : . ... :::
NP_005 GPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAAS
120 130 140 150 160 170
180 190 200 210 220
pF1KSD ELI-VYTYFFSASEEVVPEYVTLKE-----MPAVLV--FKDETY-FVYDEYEDGDLSSWI
.: : . . : .: :: : :. :. :.:.: .. ... .: ....:
NP_005 NLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFI
180 190 200 210 220 230
230 240 250 260 270 280
pF1KSD NRERFQ--NYLAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLF
... : ... :. : . : :.: .: .... . .. .. ::. . :
NP_005 QENIFGICPHMTEDNKDLIQGKDL--LIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAG
240 250 260 270 280 290
290 300 310 320 330
pF1KSD HR-DFQ------FGHMDGNDYINTLLMDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQ
:. .: :.: . .:. : .:.:.. ....... . .. .. . . .
NP_005 HKLNFAVASRKTFSH-ELSDF--GLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALER
300 310 320 330 340 350
340 350 360 370 380 390
pF1KSD FINNILDGTVEAQGGDSILQRLKRIVFDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCY
:... .::...
NP_005 FLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKN
360 370 380 390 400 410
>--
initn: 189 init1: 132 opt: 250 Z-score: 302.6 bits: 65.4 E(85289): 4.1e-10
Smith-Waterman score: 250; 41.7% identity (69.9% similar) in 103 aa overlap (29-128:384-482)
10 20 30 40 50
pF1KSD MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKK
:..:: . .:.: :. :..::::::::::.
NP_005 QDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDE-IVNNENKDV-LIEFYAPWCGHCKN
360 370 380 390 400 410
60 70 80 90 100 110
pF1KSD LEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYN---YRG
::: ..:.: : : . ..:::::. ... : . :::.::: . .. : :.:
NP_005 LEPKYKELG-EKLSKDPNIVIAKMDATA-NDVPSPYEVRGFPTIYFSPANKKLNPKKYEG
420 430 440 450 460
120 130 140 150 160 170
pF1KSD PRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELI
: .:.: . .:
NP_005 GRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL
470 480 490 500
>>XP_011508610 (OMIM: 611099) PREDICTED: protein disulfi (402 aa)
initn: 405 init1: 159 opt: 282 Z-score: 343.0 bits: 72.5 E(85289): 2.3e-12
Smith-Waterman score: 329; 46.2% identity (72.6% similar) in 106 aa overlap (25-126:160-265)
10 20 30 40 50
pF1KSD MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRND--DIWLVDFYAPW
: .: :.:: .: : :.:.:.:::::
XP_011 ALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPW
130 140 150 160 170 180
60 70 80 90 100 110
pF1KSD CGHCKKLEPIWNEVGLEMK-SIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLL-KGDLA
:::::.::: : .. :.: . . ::.. .::: . .::..:.::.::::.. ::.
XP_011 CGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESP
190 200 210 220 230 240
120 130 140 150 160 170
pF1KSD YNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDA
.: : ::..::. :
XP_011 VDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTG
250 260 270 280 290 300
>--
initn: 276 init1: 159 opt: 282 Z-score: 343.0 bits: 72.5 E(85289): 2.3e-12
Smith-Waterman score: 282; 38.4% identity (74.7% similar) in 99 aa overlap (39-135:41-136)
10 20 30 40 50 60
pF1KSD ALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGL
..:..:::.:::::::::..: : :....
XP_011 CTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAAT
20 30 40 50 60 70
70 80 90 100 110 120
pF1KSD EMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAY--NYRGPRTKDDIIEFA
.:.. :::: .:: .. :.....::.:.::::.. .. .:.: :: . :.. :
XP_011 ALKDV---VKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAA
80 90 100 110 120
130 140 150 160 170 180
pF1KSD HRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYFFSASEE
. :..
XP_011 LSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYA
130 140 150 160 170 180
>>NP_001269636 (OMIM: 611099) protein disulfide-isomeras (437 aa)
initn: 428 init1: 159 opt: 282 Z-score: 342.4 bits: 72.5 E(85289): 2.5e-12
Smith-Waterman score: 329; 46.2% identity (72.6% similar) in 106 aa overlap (25-126:157-262)
10 20 30 40 50
pF1KSD MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRND--DIWLVDFYAPW
: .: :.:: .: : :.:.:.:::::
NP_001 ALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPW
130 140 150 160 170 180
60 70 80 90 100 110
pF1KSD CGHCKKLEPIWNEVGLEMK-SIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLL-KGDLA
:::::.::: : .. :.: . . ::.. .::: . .::..:.::.::::.. ::.
NP_001 CGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESP
190 200 210 220 230 240
120 130 140 150 160 170
pF1KSD YNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDA
.: : ::..::. :
NP_001 VDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTG
250 260 270 280 290 300
>--
initn: 276 init1: 159 opt: 282 Z-score: 342.4 bits: 72.5 E(85289): 2.5e-12
Smith-Waterman score: 282; 38.4% identity (74.7% similar) in 99 aa overlap (39-135:38-133)
10 20 30 40 50 60
pF1KSD ALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGL
..:..:::.:::::::::..: : :....
NP_001 CTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAY--NYRGPRTKDDIIEFA
.:.. :::: .:: .. :.....::.:.::::.. .. .:.: :: . :.. :
NP_001 ALKDV---VKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD HRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYFFSASEE
. :..
NP_001 LSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYA
130 140 150 160 170 180
>>NP_005733 (OMIM: 611099) protein disulfide-isomerase A (440 aa)
initn: 428 init1: 159 opt: 282 Z-score: 342.4 bits: 72.5 E(85289): 2.5e-12
Smith-Waterman score: 329; 46.2% identity (72.6% similar) in 106 aa overlap (25-126:160-265)
10 20 30 40 50
pF1KSD MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRND--DIWLVDFYAPW
: .: :.:: .: : :.:.:.:::::
NP_005 ALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPW
130 140 150 160 170 180
60 70 80 90 100 110
pF1KSD CGHCKKLEPIWNEVGLEMK-SIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLL-KGDLA
:::::.::: : .. :.: . . ::.. .::: . .::..:.::.::::.. ::.
NP_005 CGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESP
190 200 210 220 230 240
120 130 140 150 160 170
pF1KSD YNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDA
.: : ::..::. :
NP_005 VDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTG
250 260 270 280 290 300
>--
initn: 276 init1: 159 opt: 282 Z-score: 342.4 bits: 72.5 E(85289): 2.5e-12
Smith-Waterman score: 282; 38.4% identity (74.7% similar) in 99 aa overlap (39-135:41-136)
10 20 30 40 50 60
pF1KSD ALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGL
..:..:::.:::::::::..: : :....
NP_005 CTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAAT
20 30 40 50 60 70
70 80 90 100 110 120
pF1KSD EMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAY--NYRGPRTKDDIIEFA
.:.. :::: .:: .. :.....::.:.::::.. .. .:.: :: . :.. :
NP_005 ALKDV---VKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAA
80 90 100 110 120
130 140 150 160 170 180
pF1KSD HRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYFFSASEE
. :..
NP_005 LSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYA
130 140 150 160 170 180
454 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 07:27:25 2016 done: Thu Nov 3 07:27:27 2016
Total Scan time: 8.800 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]