Result of FASTA (omim) for
pFN21ASDA1688
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1688, 1083 aa
1>>>pF1KSDA1688 1083 - 1083 aa - 1083 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.0708+/-0.000472; mu= -4.5575+/- 0.029
mean_var=364.3445+/-78.467, 0's: 0 Z-trim(120.3): 153 B-trim: 1833 in 2/52
Lambda= 0.067192
statistics sampled from 35205 (35435) to 35205 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.415), width: 16
Scan time: 17.540
The best scores are: opt bits E(85289)
NP_001295137 (OMIM: 615880) rho GTPase-activating (1083) 7426 735.1 5.3e-211
NP_001295136 (OMIM: 615880) rho GTPase-activating (1083) 7426 735.1 5.3e-211
XP_016869360 (OMIM: 615880) PREDICTED: rho GTPase- (1114) 5809 578.3 8.3e-164
XP_016869359 (OMIM: 615880) PREDICTED: rho GTPase- (1114) 5809 578.3 8.3e-164
NP_079527 (OMIM: 615880) rho GTPase-activating pro (1114) 5809 578.3 8.3e-164
XP_011515611 (OMIM: 615880) PREDICTED: rho GTPase- (1114) 5809 578.3 8.3e-164
XP_011515610 (OMIM: 615880) PREDICTED: rho GTPase- (1114) 5809 578.3 8.3e-164
XP_011515614 (OMIM: 615880) PREDICTED: rho GTPase- ( 957) 4641 465.0 9e-130
NP_001036134 (OMIM: 610586) rho GTPase-activating ( 653) 324 46.4 0.00064
XP_011530602 (OMIM: 610586) PREDICTED: rho GTPase- ( 653) 324 46.4 0.00064
NP_001274734 (OMIM: 610586) rho GTPase-activating ( 663) 324 46.4 0.00065
NP_001020787 (OMIM: 610586) rho GTPase-activating ( 748) 324 46.5 0.00071
NP_112595 (OMIM: 610586) rho GTPase-activating pro ( 655) 318 45.8 0.00096
XP_016871959 (OMIM: 610585) PREDICTED: rho GTPase- ( 655) 312 45.3 0.0014
XP_011538308 (OMIM: 610585) PREDICTED: rho GTPase- ( 661) 312 45.3 0.0014
NP_001242955 (OMIM: 610585) rho GTPase-activating ( 608) 309 44.9 0.0017
XP_016871960 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 307 44.7 0.0018
XP_011538314 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 307 44.7 0.0018
XP_016871961 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 307 44.7 0.0018
XP_005264733 (OMIM: 610587) PREDICTED: rho GTPase- ( 607) 308 44.8 0.0018
NP_067049 (OMIM: 610585) rho GTPase-activating pro ( 698) 309 45.0 0.0018
NP_001242954 (OMIM: 610585) rho GTPase-activating ( 704) 309 45.0 0.0018
XP_011538306 (OMIM: 610585) PREDICTED: rho GTPase- ( 704) 309 45.0 0.0018
XP_011538307 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 307 44.8 0.0019
XP_005270071 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 307 44.8 0.0019
XP_011538309 (OMIM: 610585) PREDICTED: rho GTPase- ( 637) 307 44.8 0.002
XP_016860914 (OMIM: 610587) PREDICTED: rho GTPase- ( 611) 306 44.7 0.002
XP_011538317 (OMIM: 610585) PREDICTED: rho GTPase- ( 359) 300 43.9 0.0021
NP_001242953 (OMIM: 610585) rho GTPase-activating ( 714) 307 44.8 0.0021
XP_011538304 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 307 44.8 0.0022
XP_011538305 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 307 44.8 0.0022
NP_055697 (OMIM: 610587) rho GTPase-activating pro ( 638) 300 44.1 0.0031
XP_005264732 (OMIM: 610587) PREDICTED: rho GTPase- ( 645) 300 44.1 0.0032
XP_016860913 (OMIM: 610587) PREDICTED: rho GTPase- ( 649) 300 44.1 0.0032
XP_011531509 (OMIM: 610587) PREDICTED: rho GTPase- ( 620) 299 44.0 0.0033
XP_011531508 (OMIM: 610587) PREDICTED: rho GTPase- ( 620) 299 44.0 0.0033
XP_011531510 (OMIM: 610587) PREDICTED: rho GTPase- ( 620) 299 44.0 0.0033
XP_011531511 (OMIM: 610587) PREDICTED: rho GTPase- ( 528) 297 43.7 0.0033
NP_001159748 (OMIM: 610587) rho GTPase-activating ( 639) 299 44.0 0.0034
NP_001007232 (OMIM: 610587) rho GTPase-activating ( 646) 299 44.0 0.0034
XP_016860912 (OMIM: 610587) PREDICTED: rho GTPase- ( 650) 299 44.0 0.0034
XP_011538313 (OMIM: 610585) PREDICTED: rho GTPase- ( 565) 297 43.8 0.0035
XP_016871965 (OMIM: 610585) PREDICTED: rho GTPase- ( 414) 292 43.2 0.0039
XP_016871962 (OMIM: 610585) PREDICTED: rho GTPase- ( 420) 292 43.2 0.0039
NP_001159749 (OMIM: 610587) rho GTPase-activating ( 606) 295 43.6 0.0042
XP_011538315 (OMIM: 610585) PREDICTED: rho GTPase- ( 436) 290 43.0 0.0046
>>NP_001295137 (OMIM: 615880) rho GTPase-activating prot (1083 aa)
initn: 7426 init1: 7426 opt: 7426 Z-score: 3909.2 bits: 735.1 E(85289): 5.3e-211
Smith-Waterman score: 7426; 100.0% identity (100.0% similar) in 1083 aa overlap (1-1083:1-1083)
10 20 30 40 50 60
pF1KSD MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD GVAISTYAKYCYHKLQKAALTGAKKGLKKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVAISTYAKYCYHKLQKAALTGAKKGLKKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD ERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQVDQWKVPTGLEDPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQVDQWKVPTGLEDPH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD VPASLLKLWYRELEEPLIPHEFYEQCIAHYDSPEAAVAVVHALPRINRMVLCYLIRFLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPASLLKLWYRELEEPLIPHEFYEQCIAHYDSPEAAVAVVHALPRINRMVLCYLIRFLQV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD FVQPANVAVTKMDVSNLAMVMAPNCLRCQSDDPRVIFENTRKEMSFLRVLIQHLDTSFME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVQPANVAVTKMDVSNLAMVMAPNCLRCQSDDPRVIFENTRKEMSFLRVLIQHLDTSFME
1030 1040 1050 1060 1070 1080
pF1KSD GVL
:::
NP_001 GVL
>>NP_001295136 (OMIM: 615880) rho GTPase-activating prot (1083 aa)
initn: 7426 init1: 7426 opt: 7426 Z-score: 3909.2 bits: 735.1 E(85289): 5.3e-211
Smith-Waterman score: 7426; 100.0% identity (100.0% similar) in 1083 aa overlap (1-1083:1-1083)
10 20 30 40 50 60
pF1KSD MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD GVAISTYAKYCYHKLQKAALTGAKKGLKKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVAISTYAKYCYHKLQKAALTGAKKGLKKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD ERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQVDQWKVPTGLEDPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQVDQWKVPTGLEDPH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD VPASLLKLWYRELEEPLIPHEFYEQCIAHYDSPEAAVAVVHALPRINRMVLCYLIRFLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPASLLKLWYRELEEPLIPHEFYEQCIAHYDSPEAAVAVVHALPRINRMVLCYLIRFLQV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD FVQPANVAVTKMDVSNLAMVMAPNCLRCQSDDPRVIFENTRKEMSFLRVLIQHLDTSFME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVQPANVAVTKMDVSNLAMVMAPNCLRCQSDDPRVIFENTRKEMSFLRVLIQHLDTSFME
1030 1040 1050 1060 1070 1080
pF1KSD GVL
:::
NP_001 GVL
>>XP_016869360 (OMIM: 615880) PREDICTED: rho GTPase-acti (1114 aa)
initn: 5798 init1: 5798 opt: 5809 Z-score: 3061.8 bits: 578.3 E(85289): 8.3e-164
Smith-Waterman score: 7354; 97.2% identity (97.2% similar) in 1114 aa overlap (1-1083:1-1114)
10 20 30 40 50 60
pF1KSD MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
790 800 810 820 830 840
850 860
pF1KSD -------------------------------GVAISTYAKYCYHKLQKAALTGAKKGLKK
:::::::::::::::::::::::::::::
XP_016 VTQHIKELLERNTKKKSKLRKKPKPYVEEPDGVAISTYAKYCYHKLQKAALTGAKKGLKK
850 860 870 880 890 900
870 880 890 900 910 920
pF1KSD PNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEG
910 920 930 940 950 960
930 940 950 960 970 980
pF1KSD IFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAH
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KSD YDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQ
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080
pF1KSD SDDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL
::::::::::::::::::::::::::::::::::
XP_016 SDDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL
1090 1100 1110
>>XP_016869359 (OMIM: 615880) PREDICTED: rho GTPase-acti (1114 aa)
initn: 5798 init1: 5798 opt: 5809 Z-score: 3061.8 bits: 578.3 E(85289): 8.3e-164
Smith-Waterman score: 7354; 97.2% identity (97.2% similar) in 1114 aa overlap (1-1083:1-1114)
10 20 30 40 50 60
pF1KSD MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
790 800 810 820 830 840
850 860
pF1KSD -------------------------------GVAISTYAKYCYHKLQKAALTGAKKGLKK
:::::::::::::::::::::::::::::
XP_016 VTQHIKELLERNTKKKSKLRKKPKPYVEEPDGVAISTYAKYCYHKLQKAALTGAKKGLKK
850 860 870 880 890 900
870 880 890 900 910 920
pF1KSD PNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEG
910 920 930 940 950 960
930 940 950 960 970 980
pF1KSD IFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAH
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KSD YDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQ
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080
pF1KSD SDDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL
::::::::::::::::::::::::::::::::::
XP_016 SDDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL
1090 1100 1110
>>NP_079527 (OMIM: 615880) rho GTPase-activating protein (1114 aa)
initn: 5798 init1: 5798 opt: 5809 Z-score: 3061.8 bits: 578.3 E(85289): 8.3e-164
Smith-Waterman score: 7354; 97.2% identity (97.2% similar) in 1114 aa overlap (1-1083:1-1114)
10 20 30 40 50 60
pF1KSD MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
790 800 810 820 830 840
850 860
pF1KSD -------------------------------GVAISTYAKYCYHKLQKAALTGAKKGLKK
:::::::::::::::::::::::::::::
NP_079 VTQHIKELLERNTKKKSKLRKKPKPYVEEPDGVAISTYAKYCYHKLQKAALTGAKKGLKK
850 860 870 880 890 900
870 880 890 900 910 920
pF1KSD PNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 PNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEG
910 920 930 940 950 960
930 940 950 960 970 980
pF1KSD IFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 IFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAH
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KSD YDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 YDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQ
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080
pF1KSD SDDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL
::::::::::::::::::::::::::::::::::
NP_079 SDDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL
1090 1100 1110
>>XP_011515611 (OMIM: 615880) PREDICTED: rho GTPase-acti (1114 aa)
initn: 5798 init1: 5798 opt: 5809 Z-score: 3061.8 bits: 578.3 E(85289): 8.3e-164
Smith-Waterman score: 7354; 97.2% identity (97.2% similar) in 1114 aa overlap (1-1083:1-1114)
10 20 30 40 50 60
pF1KSD MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
790 800 810 820 830 840
850 860
pF1KSD -------------------------------GVAISTYAKYCYHKLQKAALTGAKKGLKK
:::::::::::::::::::::::::::::
XP_011 VTQHIKELLERNTKKKSKLRKKPKPYVEEPDGVAISTYAKYCYHKLQKAALTGAKKGLKK
850 860 870 880 890 900
870 880 890 900 910 920
pF1KSD PNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEG
910 920 930 940 950 960
930 940 950 960 970 980
pF1KSD IFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAH
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KSD YDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQ
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080
pF1KSD SDDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL
::::::::::::::::::::::::::::::::::
XP_011 SDDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL
1090 1100 1110
>>XP_011515610 (OMIM: 615880) PREDICTED: rho GTPase-acti (1114 aa)
initn: 5798 init1: 5798 opt: 5809 Z-score: 3061.8 bits: 578.3 E(85289): 8.3e-164
Smith-Waterman score: 7354; 97.2% identity (97.2% similar) in 1114 aa overlap (1-1083:1-1114)
10 20 30 40 50 60
pF1KSD MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKRTSENQWWELFDPNTSRFYYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSGSSSPPGVFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSRRPSGSQHSPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPGGGSYSLQPSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAFSEDEALAQQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAAC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANML
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDELYIQLCRQTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK
790 800 810 820 830 840
850 860
pF1KSD -------------------------------GVAISTYAKYCYHKLQKAALTGAKKGLKK
:::::::::::::::::::::::::::::
XP_011 VTQHIKELLERNTKKKSKLRKKPKPYVEEPDGVAISTYAKYCYHKLQKAALTGAKKGLKK
850 860 870 880 890 900
870 880 890 900 910 920
pF1KSD PNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNVEEIRHAKNAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEG
910 920 930 940 950 960
930 940 950 960 970 980
pF1KSD IFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFRVPGDIDEVNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAH
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KSD YDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDSPEAAVAVVHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQ
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080
pF1KSD SDDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL
::::::::::::::::::::::::::::::::::
XP_011 SDDPRVIFENTRKEMSFLRVLIQHLDTSFMEGVL
1090 1100 1110
>>XP_011515614 (OMIM: 615880) PREDICTED: rho GTPase-acti (957 aa)
initn: 4626 init1: 4626 opt: 4641 Z-score: 2450.8 bits: 465.0 E(85289): 9e-130
Smith-Waterman score: 6186; 95.9% identity (96.3% similar) in 954 aa overlap (162-1083:4-957)
140 150 160 170 180 190
pF1KSD REGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDS-GSSSPPGVFLEKDYEIYRDYS
:: ... : . :::::::::::::::::::
XP_011 MDGFGPAQNFSENCSSPPGVFLEKDYEIYRDYS
10 20 30
200 210 220 230 240 250
pF1KSD ADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGVRSRRPSGSQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGVRSRRPSGSQH
40 50 60 70 80 90
260 270 280 290 300 310
pF1KSD SPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQPSSPRYGYEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPSLQTFAPEADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQPSSPRYGYEP
100 110 120 130 140 150
320 330 340 350 360 370
pF1KSD PLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPNKQGPPSPCQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPGRKPRPFLQPNKQGPPSPCQQ
160 170 180 190 200 210
380 390 400 410 420 430
pF1KSD LVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAPNPGGGSYSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAPNPGGGSYSLQ
220 230 240 250 260 270
440 450 460 470 480 490
pF1KSD PSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQDTLSSTGYSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPCLLRDQRLGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQDTLSSTGYSPG
280 290 300 310 320 330
500 510 520 530 540 550
pF1KSD TRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAEGEAEGARGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCGTSLAPVKRAEGEAEGARGAA
340 350 360 370 380 390
560 570 580 590 600 610
pF1KSD EPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVVRAFSEDEALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVVRAFSEDEALA
400 410 420 430 440 450
620 630 640 650 660 670
pF1KSD QQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAACAQFESSRQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQENRHWRRGTFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAACAQFESSRQSR
460 470 480 490 500 510
680 690 700 710 720 730
pF1KSD SGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANMLAWSSESIKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLFRRKVSIANMLAWSSESIKKP
520 530 540 550 560 570
740 750 760 770 780 790
pF1KSD MIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGLRDELYIQLCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGLRDELYIQLCR
580 590 600 610 620 630
800 810 820 830 840
pF1KSD QTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTK----------
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTTENFRLESLARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTKVTQHIKELLE
640 650 660 670 680 690
850 860 870
pF1KSD ---------------------GVAISTYAKYCYHKLQKAALTGAKKGLKKPNVEEIRHAK
:::::::::::::::::::::::::::::::::::::::
XP_011 RNTKKKSKLRKKPKPYVEEPDGVAISTYAKYCYHKLQKAALTGAKKGLKKPNVEEIRHAK
700 710 720 730 740 750
880 890 900 910 920 930
pF1KSD NAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAVFSPSMFGSALQEVMGMQRERYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDE
760 770 780 790 800 810
940 950 960 970 980 990
pF1KSD VNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAHYDSPEAAVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNALKLQVDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAHYDSPEAAVAV
820 830 840 850 860 870
1000 1010 1020 1030 1040 1050
pF1KSD VHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQSDDPRVIFEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHALPRINRMVLCYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQSDDPRVIFEN
880 890 900 910 920 930
1060 1070 1080
pF1KSD TRKEMSFLRVLIQHLDTSFMEGVL
::::::::::::::::::::::::
XP_011 TRKEMSFLRVLIQHLDTSFMEGVL
940 950
>>NP_001036134 (OMIM: 610586) rho GTPase-activating prot (653 aa)
initn: 219 init1: 95 opt: 324 Z-score: 191.4 bits: 46.4 E(85289): 0.00064
Smith-Waterman score: 324; 34.6% identity (64.5% similar) in 217 aa overlap (872-1078:22-234)
850 860 870 880 890 900
pF1KSD VAISTYAKYCYHKLQKAALTGAKKGLKKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQRE
:. ::.. . :. ..::. :.... ...
NP_001 MTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEK-
10 20 30 40 50
910 920 930 940 950
pF1KSD RYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQVDQWKVPT--GLEDP
:: .: : . .. . . : . ::.::.::. . :. :. : . :. . :
NP_001 RYGNRLAPML-VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDV
60 70 80 90 100
960 970 980 990 1000 1010
pF1KSD HVPASLLKLWYRELEEPLIPHEFYEQCI--AHYDSPEAAVAV------VHALPRINRMVL
:. ::::::. ::: ::.::. ::. . :. : : ..: :..:: .: .:
NP_001 HTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLL
110 120 130 140 150 160
1020 1030 1040 1050 1060 1070
pF1KSD CYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQSDDPRVIFENTRKEMSFLRVLI
:. :::. :: . .:.::.:.::: :..:: :: . .:: .:.:.: .... :.:
NP_001 KYICRFLDE-VQSYS-GVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMI
170 180 190 200 210 220
1080
pF1KSD QHLDTSFMEGVL
.. : :
NP_001 SKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESP
230 240 250 260 270 280
>>XP_011530602 (OMIM: 610586) PREDICTED: rho GTPase-acti (653 aa)
initn: 219 init1: 95 opt: 324 Z-score: 191.4 bits: 46.4 E(85289): 0.00064
Smith-Waterman score: 324; 34.6% identity (64.5% similar) in 217 aa overlap (872-1078:22-234)
850 860 870 880 890 900
pF1KSD VAISTYAKYCYHKLQKAALTGAKKGLKKPNVEEIRHAKNAVFSPSMFGSALQEVMGMQRE
:. ::.. . :. ..::. :.... ...
XP_011 MTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEK-
10 20 30 40 50
910 920 930 940 950
pF1KSD RYPERQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQVDQWKVPT--GLEDP
:: .: : . .. . . : . ::.::.::. . :. :. : . :. . :
XP_011 RYGNRLAPML-VEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDV
60 70 80 90 100
960 970 980 990 1000 1010
pF1KSD HVPASLLKLWYRELEEPLIPHEFYEQCI--AHYDSPEAAVAV------VHALPRINRMVL
:. ::::::. ::: ::.::. ::. . :. : : ..: :..:: .: .:
XP_011 HTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLL
110 120 130 140 150 160
1020 1030 1040 1050 1060 1070
pF1KSD CYLIRFLQVFVQPANVAVTKMDVSNLAMVMAPNCLRCQSDDPRVIFENTRKEMSFLRVLI
:. :::. :: . .:.::.:.::: :..:: :: . .:: .:.:.: .... :.:
XP_011 KYICRFLDE-VQSYS-GVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMI
170 180 190 200 210 220
1080
pF1KSD QHLDTSFMEGVL
.. : :
XP_011 SKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESP
230 240 250 260 270 280
1083 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 06:55:36 2016 done: Thu Nov 3 06:55:39 2016
Total Scan time: 17.540 Total Display time: 0.410
Function used was FASTA [36.3.4 Apr, 2011]