Result of FASTA (omim) for
pFN21ASDA1585
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1585, 577 aa
1>>>pF1KSDA1585 577 - 577 aa - 577 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5152+/-0.00041; mu= 9.2067+/- 0.026
mean_var=135.3396+/-26.778, 0's: 0 Z-trim(116.1): 17 B-trim: 0 in 0/54
Lambda= 0.110246
statistics sampled from 27043 (27056) to 27043 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.317), width: 16
Scan time: 10.500
The best scores are: opt bits E(85289)
NP_060603 (OMIM: 614802) E3 ubiquitin-protein liga ( 577) 3849 624.0 4.2e-178
XP_011511251 (OMIM: 614802) PREDICTED: E3 ubiquiti ( 503) 3325 540.6 4.6e-153
XP_006713747 (OMIM: 614802) PREDICTED: E3 ubiquiti ( 503) 3325 540.6 4.6e-153
NP_001138889 (OMIM: 614802) E3 ubiquitin-protein l ( 503) 3325 540.6 4.6e-153
XP_005247628 (OMIM: 614802) PREDICTED: E3 ubiquiti ( 503) 3325 540.6 4.6e-153
>>NP_060603 (OMIM: 614802) E3 ubiquitin-protein ligase M (577 aa)
initn: 3849 init1: 3849 opt: 3849 Z-score: 3318.5 bits: 624.0 E(85289): 4.2e-178
Smith-Waterman score: 3849; 100.0% identity (100.0% similar) in 577 aa overlap (1-577:1-577)
10 20 30 40 50 60
pF1KSD MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDII
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSES
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD TLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD TVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD GPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD IRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD CPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 CPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNAS
490 500 510 520 530 540
550 560 570
pF1KSD TSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
:::::::::::::::::::::::::::::::::::::
NP_060 TSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
550 560 570
>>XP_011511251 (OMIM: 614802) PREDICTED: E3 ubiquitin-pr (503 aa)
initn: 3325 init1: 3325 opt: 3325 Z-score: 2869.0 bits: 540.6 E(85289): 4.6e-153
Smith-Waterman score: 3325; 100.0% identity (100.0% similar) in 503 aa overlap (75-577:1-503)
50 60 70 80 90 100
pF1KSD CVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYK
::::::::::::::::::::::::::::::
XP_011 MMMKPSCSWCKDYEQFEENKQLSILVNCYK
10 20 30
110 120 130 140 150 160
pF1KSD KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
40 50 60 70 80 90
170 180 190 200 210 220
pF1KSD EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KSD DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KSD VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
220 230 240 250 260 270
350 360 370 380 390 400
pF1KSD SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
280 290 300 310 320 330
410 420 430 440 450 460
pF1KSD TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
340 350 360 370 380 390
470 480 490 500 510 520
pF1KSD GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
400 410 420 430 440 450
530 540 550 560 570
pF1KSD LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
460 470 480 490 500
>>XP_006713747 (OMIM: 614802) PREDICTED: E3 ubiquitin-pr (503 aa)
initn: 3325 init1: 3325 opt: 3325 Z-score: 2869.0 bits: 540.6 E(85289): 4.6e-153
Smith-Waterman score: 3325; 100.0% identity (100.0% similar) in 503 aa overlap (75-577:1-503)
50 60 70 80 90 100
pF1KSD CVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYK
::::::::::::::::::::::::::::::
XP_006 MMMKPSCSWCKDYEQFEENKQLSILVNCYK
10 20 30
110 120 130 140 150 160
pF1KSD KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
40 50 60 70 80 90
170 180 190 200 210 220
pF1KSD EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KSD DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KSD VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
220 230 240 250 260 270
350 360 370 380 390 400
pF1KSD SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
280 290 300 310 320 330
410 420 430 440 450 460
pF1KSD TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
340 350 360 370 380 390
470 480 490 500 510 520
pF1KSD GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
400 410 420 430 440 450
530 540 550 560 570
pF1KSD LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
460 470 480 490 500
>>NP_001138889 (OMIM: 614802) E3 ubiquitin-protein ligas (503 aa)
initn: 3325 init1: 3325 opt: 3325 Z-score: 2869.0 bits: 540.6 E(85289): 4.6e-153
Smith-Waterman score: 3325; 100.0% identity (100.0% similar) in 503 aa overlap (75-577:1-503)
50 60 70 80 90 100
pF1KSD CVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYK
::::::::::::::::::::::::::::::
NP_001 MMMKPSCSWCKDYEQFEENKQLSILVNCYK
10 20 30
110 120 130 140 150 160
pF1KSD KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
40 50 60 70 80 90
170 180 190 200 210 220
pF1KSD EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KSD DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KSD VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
220 230 240 250 260 270
350 360 370 380 390 400
pF1KSD SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
280 290 300 310 320 330
410 420 430 440 450 460
pF1KSD TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
340 350 360 370 380 390
470 480 490 500 510 520
pF1KSD GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
400 410 420 430 440 450
530 540 550 560 570
pF1KSD LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
460 470 480 490 500
>>XP_005247628 (OMIM: 614802) PREDICTED: E3 ubiquitin-pr (503 aa)
initn: 3325 init1: 3325 opt: 3325 Z-score: 2869.0 bits: 540.6 E(85289): 4.6e-153
Smith-Waterman score: 3325; 100.0% identity (100.0% similar) in 503 aa overlap (75-577:1-503)
50 60 70 80 90 100
pF1KSD CVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYK
::::::::::::::::::::::::::::::
XP_005 MMMKPSCSWCKDYEQFEENKQLSILVNCYK
10 20 30
110 120 130 140 150 160
pF1KSD KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTS
40 50 60 70 80 90
170 180 190 200 210 220
pF1KSD EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KSD DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KSD VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSR
220 230 240 250 260 270
350 360 370 380 390 400
pF1KSD SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLS
280 290 300 310 320 330
410 420 430 440 450 460
pF1KSD TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKC
340 350 360 370 380 390
470 480 490 500 510 520
pF1KSD GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTR
400 410 420 430 440 450
530 540 550 560 570
pF1KSD LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
460 470 480 490 500
577 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 06:43:58 2016 done: Thu Nov 3 06:43:59 2016
Total Scan time: 10.500 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]