Result of FASTA (omim) for
pFN21ASDA1470
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1470, 522 aa
1>>>pF1KSDA1470 522 - 522 aa - 522 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0646+/-0.000381; mu= 10.6028+/- 0.024
mean_var=123.8613+/-24.552, 0's: 0 Z-trim(117.0): 113 B-trim: 90 in 2/49
Lambda= 0.115241
statistics sampled from 28512 (28658) to 28512 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.336), width: 16
Scan time: 9.950
The best scores are: opt bits E(85289)
NP_001129676 (OMIM: 609587) protein RCC2 [Homo sap ( 522) 3555 602.4 1.1e-171
NP_061185 (OMIM: 609587) protein RCC2 [Homo sapien ( 522) 3555 602.4 1.1e-171
NP_001041664 (OMIM: 179710) regulator of chromosom ( 421) 394 76.8 1.4e-13
NP_001260 (OMIM: 179710) regulator of chromosome c ( 421) 394 76.8 1.4e-13
NP_001041660 (OMIM: 179710) regulator of chromosom ( 438) 394 76.8 1.5e-13
NP_001041659 (OMIM: 179710) regulator of chromosom ( 452) 394 76.8 1.5e-13
XP_016875863 (OMIM: 603524) PREDICTED: RCC1 and BT ( 340) 359 70.9 6.8e-12
XP_016875864 (OMIM: 603524) PREDICTED: RCC1 and BT ( 340) 359 70.9 6.8e-12
XP_016875865 (OMIM: 603524) PREDICTED: RCC1 and BT ( 324) 358 70.7 7.3e-12
NP_003913 (OMIM: 605109,617011) probable E3 ubiqui (4861) 365 72.6 3e-11
XP_016878194 (OMIM: 605109,617011) PREDICTED: prob (4883) 365 72.6 3e-11
XP_016878193 (OMIM: 605109,617011) PREDICTED: prob (4885) 365 72.6 3e-11
XP_016878192 (OMIM: 605109,617011) PREDICTED: prob (4891) 365 72.6 3e-11
XP_016878190 (OMIM: 605109,617011) PREDICTED: prob (4892) 365 72.6 3e-11
XP_016878191 (OMIM: 605109,617011) PREDICTED: prob (4892) 365 72.6 3e-11
XP_016878189 (OMIM: 605109,617011) PREDICTED: prob (4897) 365 72.6 3e-11
XP_016878188 (OMIM: 605109,617011) PREDICTED: prob (4909) 365 72.6 3e-11
NP_001305434 (OMIM: 605200) probable E3 ubiquitin- ( 368) 346 68.8 3.2e-11
XP_005263389 (OMIM: 605200) PREDICTED: probable E3 ( 896) 346 69.0 6.7e-11
XP_005263388 (OMIM: 605200) PREDICTED: probable E3 ( 903) 346 69.0 6.7e-11
XP_016864296 (OMIM: 605200) PREDICTED: probable E3 ( 924) 346 69.0 6.8e-11
NP_001258531 (OMIM: 605200) probable E3 ubiquitin- ( 932) 346 69.0 6.9e-11
XP_005263387 (OMIM: 605200) PREDICTED: probable E3 ( 993) 346 69.0 7.3e-11
XP_005263386 (OMIM: 605200) PREDICTED: probable E3 (1042) 346 69.1 7.5e-11
XP_016864295 (OMIM: 605200) PREDICTED: probable E3 (1042) 346 69.1 7.5e-11
XP_005263384 (OMIM: 605200) PREDICTED: probable E3 (1050) 346 69.1 7.6e-11
NP_055421 (OMIM: 605200) probable E3 ubiquitin-pro (1050) 346 69.1 7.6e-11
XP_016871530 (OMIM: 609248) PREDICTED: probable E3 ( 936) 334 67.0 2.8e-10
XP_011537899 (OMIM: 609248) PREDICTED: probable E3 ( 960) 334 67.0 2.8e-10
NP_001265114 (OMIM: 609248) probable E3 ubiquitin- ( 979) 334 67.0 2.9e-10
XP_011537898 (OMIM: 609248) PREDICTED: probable E3 ( 987) 334 67.1 2.9e-10
XP_011537896 (OMIM: 609248) PREDICTED: probable E3 (1011) 334 67.1 2.9e-10
XP_011537897 (OMIM: 609248) PREDICTED: probable E3 (1011) 334 67.1 2.9e-10
NP_056416 (OMIM: 609248) probable E3 ubiquitin-pro (1049) 334 67.1 3e-10
NP_071362 (OMIM: 609248) probable E3 ubiquitin-pro (1057) 334 67.1 3e-10
XP_011537895 (OMIM: 609248) PREDICTED: probable E3 (1073) 334 67.1 3.1e-10
XP_011537894 (OMIM: 609248) PREDICTED: probable E3 (1081) 334 67.1 3.1e-10
NP_057407 (OMIM: 608242) E3 ISG15--protein ligase (1024) 330 66.4 4.7e-10
XP_011530324 (OMIM: 608242) PREDICTED: E3 ISG15--p (1100) 330 66.4 5e-10
NP_001158608 (OMIM: 609249) probable E3 ubiquitin- ( 986) 296 60.7 2.3e-08
NP_060382 (OMIM: 609249) probable E3 ubiquitin-pro (1022) 296 60.7 2.4e-08
NP_835464 (OMIM: 609799,613824,615415) serine/thre ( 692) 292 60.0 2.7e-08
XP_011522942 (OMIM: 609799,613824,615415) PREDICTE ( 716) 292 60.0 2.8e-08
XP_011530355 (OMIM: 609249) PREDICTED: probable E3 ( 998) 291 59.9 4.1e-08
XP_005263140 (OMIM: 609249) PREDICTED: probable E3 (1034) 291 59.9 4.2e-08
XP_016879989 (OMIM: 609799,613824,615415) PREDICTE ( 666) 285 58.8 5.9e-08
XP_016879988 (OMIM: 609799,613824,615415) PREDICTE ( 705) 285 58.8 6.2e-08
XP_011522940 (OMIM: 609799,613824,615415) PREDICTE ( 729) 285 58.8 6.4e-08
XP_005268266 (OMIM: 609798,614262,617022,617025) P ( 873) 285 58.9 7.4e-08
NP_001316166 (OMIM: 609798,614262,617022,617025) s ( 991) 285 58.9 8.2e-08
>>NP_001129676 (OMIM: 609587) protein RCC2 [Homo sapiens (522 aa)
initn: 3555 init1: 3555 opt: 3555 Z-score: 3203.5 bits: 602.4 E(85289): 1.1e-171
Smith-Waterman score: 3555; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KSD MPRKKAAAAAWEEPSSGNGTARAGPRKRGGPAGRKRERPERCSSSSGGGSSGDEDGLELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRKKAAAAAWEEPSSGNGTARAGPRKRGGPAGRKRERPERCSSSSGGGSSGDEDGLELD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GAPGGGKRAARPATAGKAGGAAVVITEPEHTKERVKLEGSKCKGQLLIFGATNWDLIGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAPGGGKRAARPATAGKAGGAAVVITEPEHTKERVKLEGSKCKGQLLIFGATNWDLIGRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD IEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD RLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGATNTSRESTMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGATNTSRESTMY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD PKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFGELGYGDHKPKSSTAAQEVKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFGELGYGDHKPKSSTAAQEVKT
430 440 450 460 470 480
490 500 510 520
pF1KSD LDGIFSEQVAMGYSHSLVIARDESETEKEKIKKLPEYNPRTL
::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGIFSEQVAMGYSHSLVIARDESETEKEKIKKLPEYNPRTL
490 500 510 520
>>NP_061185 (OMIM: 609587) protein RCC2 [Homo sapiens] (522 aa)
initn: 3555 init1: 3555 opt: 3555 Z-score: 3203.5 bits: 602.4 E(85289): 1.1e-171
Smith-Waterman score: 3555; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KSD MPRKKAAAAAWEEPSSGNGTARAGPRKRGGPAGRKRERPERCSSSSGGGSSGDEDGLELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MPRKKAAAAAWEEPSSGNGTARAGPRKRGGPAGRKRERPERCSSSSGGGSSGDEDGLELD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GAPGGGKRAARPATAGKAGGAAVVITEPEHTKERVKLEGSKCKGQLLIFGATNWDLIGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GAPGGGKRAARPATAGKAGGAAVVITEPEHTKERVKLEGSKCKGQLLIFGATNWDLIGRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD IEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 IEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD RLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGATNTSRESTMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGATNTSRESTMY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD PKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFGELGYGDHKPKSSTAAQEVKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFGELGYGDHKPKSSTAAQEVKT
430 440 450 460 470 480
490 500 510 520
pF1KSD LDGIFSEQVAMGYSHSLVIARDESETEKEKIKKLPEYNPRTL
::::::::::::::::::::::::::::::::::::::::::
NP_061 LDGIFSEQVAMGYSHSLVIARDESETEKEKIKKLPEYNPRTL
490 500 510 520
>>NP_001041664 (OMIM: 179710) regulator of chromosome co (421 aa)
initn: 347 init1: 111 opt: 394 Z-score: 364.6 bits: 76.8 E(85289): 1.4e-13
Smith-Waterman score: 394; 24.8% identity (58.1% similar) in 387 aa overlap (132-506:50-421)
110 120 130 140 150 160
pF1KSD CKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAH
::.:. .. :... .: . . . :
NP_001 SKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVM-ERKKPALVSIPEDVVQAEAGGMH
20 30 40 50 60 70
170 180 190 200 210
pF1KSD SLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLS--HEVIVSAACGRNHTLALTE
.. .. :...:.: :..: ::. ::. ::. ... : .: .:... : .:: :::.
NP_001 TVCLSKSGQVYSFGCNDEGALGR-DTS-VEGSEMVPGKVELQEKVVQVSAGDSHTAALTD
80 90 100 110 120 130
220 230 240 250 260 270
pF1KSD TGSVFAFG--ENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYS
: :: .: ... : .:: . :.:.. . :..:.: : . ... :.::.
NP_001 DGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASGNDHLVMLTADGDLYT
140 150 160 170 180 190
280 290 300 310 320 330
pF1KSD FGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVAC
.:: : ::::. . : :. : . :::. : . :.. .. .: .:. :
NP_001 LGCGEQGQLGRVPE-LFANRGGRQGLERLLVPKCVML---KSRGSR----GHVRFQDAFC
200 210 220 230 240
340 350 360 370 380 390
pF1KSD GANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSF
:: :.... . .:...:...: .:: .. ..:. . : .. . .: .
NP_001 GAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTV
250 260 270 280 290 300
400 410 420 430 440
pF1KSD AVSEVGGLFFWGATNTSR-------ESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADES
.. : . : .. .: : : .. : . . :.::: : . :. :
NP_001 CMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTKDGR
310 320 330 340 350 360
450 460 470 480 490 500
pF1KSD TISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEKE
...:: . .. .:: :. . : . . : :.. .:. : .:......:. ..
NP_001 VFAWGMGTNY-QLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS
370 380 390 400 410 420
510 520
pF1KSD KIKKLPEYNPRTL
>>NP_001260 (OMIM: 179710) regulator of chromosome conde (421 aa)
initn: 347 init1: 111 opt: 394 Z-score: 364.6 bits: 76.8 E(85289): 1.4e-13
Smith-Waterman score: 394; 24.8% identity (58.1% similar) in 387 aa overlap (132-506:50-421)
110 120 130 140 150 160
pF1KSD CKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAH
::.:. .. :... .: . . . :
NP_001 SKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVM-ERKKPALVSIPEDVVQAEAGGMH
20 30 40 50 60 70
170 180 190 200 210
pF1KSD SLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLS--HEVIVSAACGRNHTLALTE
.. .. :...:.: :..: ::. ::. ::. ... : .: .:... : .:: :::.
NP_001 TVCLSKSGQVYSFGCNDEGALGR-DTS-VEGSEMVPGKVELQEKVVQVSAGDSHTAALTD
80 90 100 110 120 130
220 230 240 250 260 270
pF1KSD TGSVFAFG--ENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYS
: :: .: ... : .:: . :.:.. . :..:.: : . ... :.::.
NP_001 DGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASGNDHLVMLTADGDLYT
140 150 160 170 180 190
280 290 300 310 320 330
pF1KSD FGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVAC
.:: : ::::. . : :. : . :::. : . :.. .. .: .:. :
NP_001 LGCGEQGQLGRVPE-LFANRGGRQGLERLLVPKCVML---KSRGSR----GHVRFQDAFC
200 210 220 230 240
340 350 360 370 380 390
pF1KSD GANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSF
:: :.... . .:...:...: .:: .. ..:. . : .. . .: .
NP_001 GAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTV
250 260 270 280 290 300
400 410 420 430 440
pF1KSD AVSEVGGLFFWGATNTSR-------ESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADES
.. : . : .. .: : : .. : . . :.::: : . :. :
NP_001 CMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTKDGR
310 320 330 340 350 360
450 460 470 480 490 500
pF1KSD TISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEKE
...:: . .. .:: :. . : . . : :.. .:. : .:......:. ..
NP_001 VFAWGMGTNY-QLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS
370 380 390 400 410 420
510 520
pF1KSD KIKKLPEYNPRTL
>>NP_001041660 (OMIM: 179710) regulator of chromosome co (438 aa)
initn: 347 init1: 111 opt: 394 Z-score: 364.4 bits: 76.8 E(85289): 1.5e-13
Smith-Waterman score: 394; 24.8% identity (58.1% similar) in 387 aa overlap (132-506:67-438)
110 120 130 140 150 160
pF1KSD CKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAH
::.:. .. :... .: . . . :
NP_001 ARSCQVSHRSHSTEPGLVLTLGQGDVGQLGLGENVM-ERKKPALVSIPEDVVQAEAGGMH
40 50 60 70 80 90
170 180 190 200 210
pF1KSD SLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLS--HEVIVSAACGRNHTLALTE
.. .. :...:.: :..: ::. ::. ::. ... : .: .:... : .:: :::.
NP_001 TVCLSKSGQVYSFGCNDEGALGR-DTS-VEGSEMVPGKVELQEKVVQVSAGDSHTAALTD
100 110 120 130 140 150
220 230 240 250 260 270
pF1KSD TGSVFAFG--ENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYS
: :: .: ... : .:: . :.:.. . :..:.: : . ... :.::.
NP_001 DGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASGNDHLVMLTADGDLYT
160 170 180 190 200 210
280 290 300 310 320 330
pF1KSD FGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVAC
.:: : ::::. . : :. : . :::. : . :.. .. .: .:. :
NP_001 LGCGEQGQLGRVPE-LFANRGGRQGLERLLVPKCVML---KSRGSR----GHVRFQDAFC
220 230 240 250 260
340 350 360 370 380 390
pF1KSD GANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSF
:: :.... . .:...:...: .:: .. ..:. . : .. . .: .
NP_001 GAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTV
270 280 290 300 310 320
400 410 420 430 440
pF1KSD AVSEVGGLFFWGATNTSR-------ESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADES
.. : . : .. .: : : .. : . . :.::: : . :. :
NP_001 CMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTKDGR
330 340 350 360 370 380
450 460 470 480 490 500
pF1KSD TISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEKE
...:: . .. .:: :. . : . . : :.. .:. : .:......:. ..
NP_001 VFAWGMGTNY-QLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS
390 400 410 420 430
510 520
pF1KSD KIKKLPEYNPRTL
>>NP_001041659 (OMIM: 179710) regulator of chromosome co (452 aa)
initn: 347 init1: 111 opt: 394 Z-score: 364.2 bits: 76.8 E(85289): 1.5e-13
Smith-Waterman score: 394; 24.8% identity (58.1% similar) in 387 aa overlap (132-506:81-452)
110 120 130 140 150 160
pF1KSD CKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAH
::.:. .. :... .: . . . :
NP_001 QKTRPVSHRSHSTEPGLVLTLGQGDVGQLGLGENVM-ERKKPALVSIPEDVVQAEAGGMH
60 70 80 90 100
170 180 190 200 210
pF1KSD SLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLS--HEVIVSAACGRNHTLALTE
.. .. :...:.: :..: ::. ::. ::. ... : .: .:... : .:: :::.
NP_001 TVCLSKSGQVYSFGCNDEGALGR-DTS-VEGSEMVPGKVELQEKVVQVSAGDSHTAALTD
110 120 130 140 150 160
220 230 240 250 260 270
pF1KSD TGSVFAFG--ENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYS
: :: .: ... : .:: . :.:.. . :..:.: : . ... :.::.
NP_001 DGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLD-VPVVKVASGNDHLVMLTADGDLYT
170 180 190 200 210 220
280 290 300 310 320 330
pF1KSD FGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVAC
.:: : ::::. . : :. : . :::. : . :.. .. .: .:. :
NP_001 LGCGEQGQLGRVPE-LFANRGGRQGLERLLVPKCVML---KSRGSR----GHVRFQDAFC
230 240 250 260 270
340 350 360 370 380 390
pF1KSD GANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSF
:: :.... . .:...:...: .:: .. ..:. . : .. . .: .
NP_001 GAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTV
280 290 300 310 320 330
400 410 420 430 440
pF1KSD AVSEVGGLFFWGATNTSR-------ESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADES
.. : . : .. .: : : .. : . . :.::: : . :. :
NP_001 CMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYAVTKDGR
340 350 360 370 380 390
450 460 470 480 490 500
pF1KSD TISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEKE
...:: . .. .:: :. . : . . : :.. .:. : .:......:. ..
NP_001 VFAWGMGTNY-QLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS
400 410 420 430 440 450
510 520
pF1KSD KIKKLPEYNPRTL
>>XP_016875863 (OMIM: 603524) PREDICTED: RCC1 and BTB do (340 aa)
initn: 514 init1: 213 opt: 359 Z-score: 334.5 bits: 70.9 E(85289): 6.8e-12
Smith-Waterman score: 394; 31.7% identity (60.1% similar) in 243 aa overlap (134-373:94-310)
110 120 130 140 150 160
pF1KSD GQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSL
:. :.: : : .. . :: . : .
XP_016 AGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLDSLNGKKIACLSYGS-GPHIV
70 80 90 100 110 120
170 180 190 200 210 220
pF1KSD LITTEGKLWSWGRNEKGQLGHGDTKRVEAP-RLIEGLSHEVIVSAACGRNHTLALTETGS
: ::::....::.: .:::.: :.. .: .. .::.. .. .::: :.:.:: :
XP_016 LATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGE
130 140 150 160 170 180
230 240 250 260 270 280
pF1KSD VFAFGENKMGQLGLGNQTDAVPSPAQIM--YNGQPITKMACGAEFSMIMDCKGNLYSFGC
:::.: :. ::.: :. .. : : .. ... .. .::: : . :..: .:
XP_016 VFAWGYNNSGQVGSGSTVNQ-PIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGY
190 200 210 220 230 240
290 300 310 320 330 340
pF1KSD PEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGAN
:::: ...:. . .: ::: . .. :. ::::
XP_016 NGNGQLGLGNSGN------------QPTPCRVAAL------------QGIRVQRVACGYA
250 260 270
350 360 370 380 390 400
pF1KSD HTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVS
::::: .. .:..:: ..::.:: ...... :
XP_016 HTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRILSERSHCPCESSDENGV
280 290 300 310 320 330
410 420 430 440 450 460
pF1KSD EVGGLFFWGATNTSRESTMYPKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFG
XP_016 PRG
340
>>XP_016875864 (OMIM: 603524) PREDICTED: RCC1 and BTB do (340 aa)
initn: 514 init1: 213 opt: 359 Z-score: 334.5 bits: 70.9 E(85289): 6.8e-12
Smith-Waterman score: 394; 31.7% identity (60.1% similar) in 243 aa overlap (134-373:94-310)
110 120 130 140 150 160
pF1KSD GQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSL
:. :.: : : .. . :: . : .
XP_016 AGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLDSLNGKKIACLSYGS-GPHIV
70 80 90 100 110 120
170 180 190 200 210 220
pF1KSD LITTEGKLWSWGRNEKGQLGHGDTKRVEAP-RLIEGLSHEVIVSAACGRNHTLALTETGS
: ::::....::.: .:::.: :.. .: .. .::.. .. .::: :.:.:: :
XP_016 LATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGE
130 140 150 160 170 180
230 240 250 260 270 280
pF1KSD VFAFGENKMGQLGLGNQTDAVPSPAQIM--YNGQPITKMACGAEFSMIMDCKGNLYSFGC
:::.: :. ::.: :. .. : : .. ... .. .::: : . :..: .:
XP_016 VFAWGYNNSGQVGSGSTVNQ-PIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGY
190 200 210 220 230 240
290 300 310 320 330 340
pF1KSD PEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGAN
:::: ...:. . .: ::: . .. :. ::::
XP_016 NGNGQLGLGNSGN------------QPTPCRVAAL------------QGIRVQRVACGYA
250 260 270
350 360 370 380 390 400
pF1KSD HTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVS
::::: .. .:..:: ..::.:: ...... :
XP_016 HTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRILSERSHCPCESSDENGV
280 290 300 310 320 330
410 420 430 440 450 460
pF1KSD EVGGLFFWGATNTSRESTMYPKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFG
XP_016 PRG
340
>>XP_016875865 (OMIM: 603524) PREDICTED: RCC1 and BTB do (324 aa)
initn: 514 init1: 213 opt: 358 Z-score: 334.0 bits: 70.7 E(85289): 7.3e-12
Smith-Waterman score: 394; 31.7% identity (60.1% similar) in 243 aa overlap (134-373:94-310)
110 120 130 140 150 160
pF1KSD GQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSL
:. :.: : : .. . :: . : .
XP_016 AGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLDSLNGKKIACLSYGS-GPHIV
70 80 90 100 110 120
170 180 190 200 210 220
pF1KSD LITTEGKLWSWGRNEKGQLGHGDTKRVEAP-RLIEGLSHEVIVSAACGRNHTLALTETGS
: ::::....::.: .:::.: :.. .: .. .::.. .. .::: :.:.:: :
XP_016 LATTEGEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGE
130 140 150 160 170 180
230 240 250 260 270 280
pF1KSD VFAFGENKMGQLGLGNQTDAVPSPAQIM--YNGQPITKMACGAEFSMIMDCKGNLYSFGC
:::.: :. ::.: :. .. : : .. ... .. .::: : . :..: .:
XP_016 VFAWGYNNSGQVGSGSTVNQ-PIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGY
190 200 210 220 230 240
290 300 310 320 330 340
pF1KSD PEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGAN
:::: ...:. . .: ::: . .. :. ::::
XP_016 NGNGQLGLGNSGN------------QPTPCRVAAL------------QGIRVQRVACGYA
250 260 270
350 360 370 380 390 400
pF1KSD HTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVS
::::: .. .:..:: ..::.:: ...... :
XP_016 HTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRVCGQN
280 290 300 310 320
410 420 430 440 450 460
pF1KSD EVGGLFFWGATNTSRESTMYPKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFG
>>NP_003913 (OMIM: 605109,617011) probable E3 ubiquitin- (4861 aa)
initn: 431 init1: 286 opt: 365 Z-score: 323.1 bits: 72.6 E(85289): 3e-11
Smith-Waterman score: 456; 33.0% identity (60.8% similar) in 288 aa overlap (145-398:4076-4357)
120 130 140 150 160 170
pF1KSD DLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAA--HSLLITTEGKLW
: : : .:. ::.. ::. .: :...
NP_003 GTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVT-SCGSDGHSMALTESGEVF
4050 4060 4070 4080 4090 4100
180 190 200 210 220 230
pF1KSD SWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMG
::: .. :.::::.. : . :: ::.:. : .:. .:: .:. ..: :..:.::.. .:
NP_003 SWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYG
4110 4120 4130 4140 4150 4160
240 250 260 270 280
pF1KSD QLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNL-YSFGCPEYGQLG-HN
.::::: .. : .. .: : ..::: . .. .. :.. ..:: .::.:: :
NP_003 RLGLGNTSNK-KLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGN
4170 4180 4190 4200 4210 4220
290 300 310 320
pF1KSD SDGKFIARAQRIEYDCELVPRRVA----IFIEKTKDGQI----------LP---------
: .: . :.:. : . ..:: . . ::::.. ::
NP_003 STAK--SSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNR
4230 4240 4250 4260 4270 4280
330 340 350 360 370 380
pF1KSD ---VP---NVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFD
.: .:...::: ::.:::.: :. :..:: .. :.:: .. . : ::
NP_003 PQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGHTNHVREPTLVT--G
4290 4300 4310 4320 4330
390 400 410 420 430 440
pF1KSD FPGRGASQIYAGYTCSFAVSEVGGLFFWGATNTSRESTMYPKAVQDLCGWRIRSLACGKS
. :... :: :: : :
NP_003 LQGKNVRQISAGRCHSAAWTAPPVPPRAPGVSVPLQLGLPDTVPPQYGALREVSIHTVRA
4340 4350 4360 4370 4380 4390
>--
initn: 485 init1: 180 opt: 242 Z-score: 212.5 bits: 52.2 E(85289): 4.2e-05
Smith-Waterman score: 444; 28.6% identity (60.0% similar) in 360 aa overlap (151-497:406-731)
130 140 150 160 170
pF1KSD EVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGS-CAAHSLLITTEGKLWSWGRNEK
.:. .:. : ...:.:.:.. . :..
NP_003 VWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYC---TFVISTDGSVRACGKGSY
380 390 400 410 420 430
180 190 200 210 220 230
pF1KSD GQLGHGDTKRVEAPRLIEGLSHEVI--VSAACGRN-HTLALTETGSVFAFGENKMGQLGL
:.:: ::.. . . . :. : ::.. : . ::::.: : ::..:.. .:.::
NP_003 GRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGH
440 450 460 470 480 490
240 250 260 270 280 290
pF1KSD GNQ-TDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFI
::. :. :. : .:. .. .. : . : . :.::..: ..:.::: :
NP_003 GNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGH---GDSN
500 510 520 530 540
300 310 320 330 340 350
pF1KSD ARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWG
.: .: : :: . : : .:.::..::..:... :. :.
NP_003 SRN---------IPTLV-------KD-----ISN--VGEVSCGSSHTIALSKDGRTV-WS
550 560 570 580
360 370 380 390 400
pF1KSD FGG--YGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWG----
::: :.:::.. . . :.... .. : .. :: :.:.. .: .. ::
NP_003 FGGGDNGKLGHGDTNRVYKPKVIEALQ--GMFIRKVCAGSQSSLALTSTGQVYAWGCGAC
590 600 610 620 630 640
410 420 430 440 450 460
pF1KSD -ATNTSRESTMYPKAVQDLCGWRIRSLACGKSS-IIVAADESTISWGPSPTFGELGYGDH
. ..:. ... :: ...: . :: ... : : . .. :. . .:: . ..:. : :.
NP_003 LGCGSSEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWG-NNSMGQCGQGN-
650 660 670 680 690 700
470 480 490 500 510 520
pF1KSD KPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEKEKIKKLPEYNPRTL
. : ..:. :::: .:.. : ::::
NP_003 STGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHL
710 720 730 740 750 760
522 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 06:24:32 2016 done: Thu Nov 3 06:24:33 2016
Total Scan time: 9.950 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]