Result of FASTA (omim) for
pFN21ASDA1344
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1344, 825 aa
1>>>pF1KSDA1344 825 - 825 aa - 825 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3707+/-0.000471; mu= 20.3896+/- 0.030
mean_var=68.2183+/-13.972, 0's: 0 Z-trim(108.6): 38 B-trim: 312 in 1/54
Lambda= 0.155283
statistics sampled from 16645 (16659) to 16645 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.533), E-opt: 0.2 (0.195), width: 16
Scan time: 11.310
The best scores are: opt bits E(85289)
NP_065835 (OMIM: 616179) thioredoxin domain-contai ( 825) 5350 1208.5 0
NP_001153519 (OMIM: 616179) thioredoxin domain-con ( 820) 5302 1197.7 0
XP_016876994 (OMIM: 616179) PREDICTED: thioredoxin ( 465) 2812 639.7 8.6e-183
NP_110437 (OMIM: 616412) thioredoxin domain-contai ( 432) 158 45.2 0.00077
>>NP_065835 (OMIM: 616179) thioredoxin domain-containing (825 aa)
initn: 5350 init1: 5350 opt: 5350 Z-score: 6471.8 bits: 1208.5 E(85289): 0
Smith-Waterman score: 5350; 99.8% identity (100.0% similar) in 825 aa overlap (1-825:1-825)
10 20 30 40 50 60
pF1KSD MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DVNAIVAHVLFALLFSEVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_065 DVNAIVAHVLFALLFSEVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FVYGTTYQFVLTTEIALLESIGSEDVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FVYGTTYQFVLTTEIALLESIGSEDVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD HLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 HLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD AGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD DNDMEGPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DNDMEGPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD VSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIKMYKKGENPVSYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIKMYKKGENPVSYA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD GMLGTKDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSVSVLGLFSPTMKTA
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GMLGTEDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSVSVLGLFSPTMKTA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD KEDFSEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEGKIESIPLASTHAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KEDFSEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEGKIESIPLASTHAQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD DIVQIITDALLEMFPEITVENLPSYFRLQKPLLILFSDGTVNPQYKKAILTLVKQKYLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DIVQIITDALLEMFPEITVENLPSYFRLQKPLLILFSDGTVNPQYKKAILTLVKQKYLDS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD FTPCWLNLKNTPVGRGILRAYFDPLPPLPLLVLVNLHSGGQVFAFPSDQAIIEENLVLWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FTPCWLNLKNTPVGRGILRAYFDPLPPLPLLVLVNLHSGGQVFAFPSDQAIIEENLVLWL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KKLEAGLENHITILPAQEWKPPLPAYDFLSMIDAATSQRGTRKVPKCMKETDVQENDKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KKLEAGLENHITILPAQEWKPPLPAYDFLSMIDAATSQRGTRKVPKCMKETDVQENDKEQ
730 740 750 760 770 780
790 800 810 820
pF1KSD HEDKSAVRKEPIETLRIKHWNRSNWFKEAEKSFRRDKELGCSKVN
:::::::::::::::::::::::::::::::::::::::::::::
NP_065 HEDKSAVRKEPIETLRIKHWNRSNWFKEAEKSFRRDKELGCSKVN
790 800 810 820
>>NP_001153519 (OMIM: 616179) thioredoxin domain-contain (820 aa)
initn: 4457 init1: 4457 opt: 5302 Z-score: 6413.7 bits: 1197.7 E(85289): 0
Smith-Waterman score: 5302; 99.2% identity (99.4% similar) in 825 aa overlap (1-825:1-820)
10 20 30 40 50 60
pF1KSD MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DVNAIVAHVLFALLFSEVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAG
::::::::::: :::::::::::::::::::::::::::::::::::::::::::.
NP_001 DVNAIVAHVLF-----EVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAA
130 140 150 160 170
190 200 210 220 230 240
pF1KSD FVYGTTYQFVLTTEIALLESIGSEDVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVYGTTYQFVLTTEIALLESIGSEDVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD HLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGK
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD AGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD DNDMEGPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNDMEGPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQA
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD VSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIKMYKKGENPVSYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIKMYKKGENPVSYA
420 430 440 450 460 470
490 500 510 520 530 540
pF1KSD GMLGTKDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSVSVLGLFSPTMKTA
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMLGTEDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSVSVLGLFSPTMKTA
480 490 500 510 520 530
550 560 570 580 590 600
pF1KSD KEDFSEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEGKIESIPLASTHAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEDFSEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEGKIESIPLASTHAQ
540 550 560 570 580 590
610 620 630 640 650 660
pF1KSD DIVQIITDALLEMFPEITVENLPSYFRLQKPLLILFSDGTVNPQYKKAILTLVKQKYLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIVQIITDALLEMFPEITVENLPSYFRLQKPLLILFSDGTVNPQYKKAILTLVKQKYLDS
600 610 620 630 640 650
670 680 690 700 710 720
pF1KSD FTPCWLNLKNTPVGRGILRAYFDPLPPLPLLVLVNLHSGGQVFAFPSDQAIIEENLVLWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTPCWLNLKNTPVGRGILRAYFDPLPPLPLLVLVNLHSGGQVFAFPSDQAIIEENLVLWL
660 670 680 690 700 710
730 740 750 760 770 780
pF1KSD KKLEAGLENHITILPAQEWKPPLPAYDFLSMIDAATSQRGTRKVPKCMKETDVQENDKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLEAGLENHITILPAQEWKPPLPAYDFLSMIDAATSQRGTRKVPKCMKETDVQENDKEQ
720 730 740 750 760 770
790 800 810 820
pF1KSD HEDKSAVRKEPIETLRIKHWNRSNWFKEAEKSFRRDKELGCSKVN
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEDKSAVRKEPIETLRIKHWNRSNWFKEAEKSFRRDKELGCSKVN
780 790 800 810 820
>>XP_016876994 (OMIM: 616179) PREDICTED: thioredoxin dom (465 aa)
initn: 2812 init1: 2812 opt: 2812 Z-score: 3402.7 bits: 639.7 E(85289): 8.6e-183
Smith-Waterman score: 2812; 99.8% identity (100.0% similar) in 437 aa overlap (1-437:1-437)
10 20 30 40 50 60
pF1KSD MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD DVNAIVAHVLFALLFSEVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 DVNAIVAHVLFALLFSEVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD FVYGTTYQFVLTTEIALLESIGSEDVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVYGTTYQFVLTTEIALLESIGSEDVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD HLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD AGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD DNDMEGPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNDMEGPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD VSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIKMYKKGENPVSYA
:::::::::::::::::
XP_016 VSMAFLQSYIDVAVKLKVVWGHLVCSLQHTWLAEKGRQSGHLGNV
430 440 450 460
>>NP_110437 (OMIM: 616412) thioredoxin domain-containing (432 aa)
initn: 176 init1: 102 opt: 158 Z-score: 189.9 bits: 45.2 E(85289): 0.00077
Smith-Waterman score: 158; 24.2% identity (57.6% similar) in 132 aa overlap (397-526:67-196)
370 380 390 400 410 420
pF1KSD PDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDSIVLFYAGWQAVSMAFL
: . :. .... .:.:.: : . . .
NP_110 RAQEAAAAAADGPPAADGEDGQDPHSKHLYTADMFTHGIQSAAHFVMFFAPWCGHCQRLQ
40 50 60 70 80 90
430 440 450 460 470 480
pF1KSD QSYIDVAVKLKGT--STMLLTRINCADWSDVCTKQNVTEFPIIKMYKKGENPVSYAGMLG
.. :.. : .. . . .....:. ::::. :.: .: .:..: :.. :.: :
NP_110 PTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRD
100 110 120 130 140 150
490 500 510 520 530 540
pF1KSD TKDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSVSVLGLFSPTMKTAKEDF
. : ... . :: : :.: . :: . : :.
NP_110 FQTLENWMLQTLNEEPV--TPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFA
160 170 180 190 200 210
550 560 570 580 590 600
pF1KSD SEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEGKIESIPLASTHAQDIVQ
NP_110 PWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKV
220 230 240 250 260 270
825 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:54:02 2016 done: Thu Nov 3 05:54:03 2016
Total Scan time: 11.310 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]