Result of FASTA (omim) for
pFN21ASDA0886
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0886, 1192 aa
1>>>pF1KSDA0886 1192 - 1192 aa - 1192 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.6766+/-0.000528; mu= -23.4722+/- 0.033
mean_var=703.6046+/-143.711, 0's: 0 Z-trim(123.2): 41 B-trim: 0 in 0/62
Lambda= 0.048351
statistics sampled from 42663 (42704) to 42663 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.501), width: 16
Scan time: 14.280
The best scores are: opt bits E(85289)
NP_065393 (OMIM: 604475) reticulon-4 isoform A [Ho (1192) 7621 547.8 1.5e-154
NP_001308790 (OMIM: 604475) reticulon-4 isoform E ( 986) 6195 448.2 1.2e-124
XP_005264491 (OMIM: 604475) PREDICTED: reticulon-4 ( 986) 6195 448.2 1.2e-124
NP_001308788 (OMIM: 604475) reticulon-4 isoform E ( 986) 6195 448.2 1.2e-124
NP_001308791 (OMIM: 604475) reticulon-4 isoform E ( 986) 6195 448.2 1.2e-124
XP_016860007 (OMIM: 604475) PREDICTED: reticulon-4 ( 986) 6195 448.2 1.2e-124
NP_001308833 (OMIM: 604475) reticulon-4 isoform E ( 986) 6195 448.2 1.2e-124
XP_016860008 (OMIM: 604475) PREDICTED: reticulon-4 ( 986) 6195 448.2 1.2e-124
NP_001308789 (OMIM: 604475) reticulon-4 isoform E ( 986) 6195 448.2 1.2e-124
NP_001308792 (OMIM: 604475) reticulon-4 isoform E ( 986) 6195 448.2 1.2e-124
NP_997404 (OMIM: 604475) reticulon-4 isoform E [Ho ( 986) 6195 448.2 1.2e-124
NP_997403 (OMIM: 604475) reticulon-4 isoform D [Ho ( 392) 1413 114.3 1.5e-24
NP_722550 (OMIM: 604475) reticulon-4 isoform B [Ho ( 373) 1298 106.3 3.8e-22
NP_008939 (OMIM: 604475) reticulon-4 isoform C [Ho ( 199) 1174 97.4 9.5e-20
NP_066959 (OMIM: 600865) reticulon-1 isoform A [Ho ( 776) 922 80.3 5.2e-14
NP_996734 (OMIM: 600865) reticulon-1 isoform C [Ho ( 208) 873 76.4 2.1e-13
XP_016877067 (OMIM: 600865) PREDICTED: reticulon-1 ( 193) 865 75.9 2.9e-13
NP_006045 (OMIM: 604249) reticulon-3 isoform a [Ho ( 236) 795 71.1 9.8e-12
NP_958832 (OMIM: 604249) reticulon-3 isoform c [Ho ( 255) 793 70.9 1.1e-11
NP_001252519 (OMIM: 604249) reticulon-3 isoform f ( 920) 801 71.9 2.1e-11
NP_958831 (OMIM: 604249) reticulon-3 isoform b [Ho (1013) 801 72.0 2.2e-11
NP_001252518 (OMIM: 604249) reticulon-3 isoform e (1032) 801 72.0 2.2e-11
NP_958833 (OMIM: 604249) reticulon-3 isoform d [Ho ( 241) 673 62.5 3.6e-09
XP_011543033 (OMIM: 604249) PREDICTED: reticulon-3 ( 260) 671 62.4 4.2e-09
XP_011543032 (OMIM: 604249) PREDICTED: reticulon-3 (1037) 679 63.5 8.2e-09
NP_996783 (OMIM: 603183,604805) reticulon-2 isofor ( 472) 626 59.5 5.9e-08
NP_996784 (OMIM: 603183,604805) reticulon-2 isofor ( 205) 608 58.0 7.4e-08
NP_005610 (OMIM: 603183,604805) reticulon-2 isofor ( 545) 620 59.1 8.7e-08
>>NP_065393 (OMIM: 604475) reticulon-4 isoform A [Homo s (1192 aa)
initn: 7621 init1: 7621 opt: 7621 Z-score: 2895.5 bits: 547.8 E(85289): 1.5e-154
Smith-Waterman score: 7621; 100.0% identity (100.0% similar) in 1192 aa overlap (1-1192:1-1192)
10 20 30 40 50 60
pF1KSD MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEEDEDEDLEELEVLERKPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELEYSEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD GSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKEDEVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD SSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNLESKV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD DKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIATNIF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD PLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLTKVTE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQLCPSF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD EESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENPPPYE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD EAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFSDYSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD MAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSFESMI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD EYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELSTAVY
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD SNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSHKSEI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD ANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVSALAT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD QAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD FGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD VAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190
pF1KSD LILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
1150 1160 1170 1180 1190
>>NP_001308790 (OMIM: 604475) reticulon-4 isoform E [Hom (986 aa)
initn: 6195 init1: 6195 opt: 6195 Z-score: 2359.0 bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)
180 190 200 210 220 230
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
::::::::::::::::::::::::::::::
NP_001 MDLKEQPGNTISAGQEDFPSVLLETAASLP
10 20 30
240 250 260 270 280 290
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
40 50 60 70 80 90
300 310 320 330 340 350
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
100 110 120 130 140 150
360 370 380 390 400 410
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
160 170 180 190 200 210
420 430 440 450 460 470
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
220 230 240 250 260 270
480 490 500 510 520 530
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
280 290 300 310 320 330
540 550 560 570 580 590
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
340 350 360 370 380 390
600 610 620 630 640 650
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
400 410 420 430 440 450
660 670 680 690 700 710
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
460 470 480 490 500 510
720 730 740 750 760 770
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
520 530 540 550 560 570
780 790 800 810 820 830
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
580 590 600 610 620 630
840 850 860 870 880 890
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
640 650 660 670 680 690
900 910 920 930 940 950
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
700 710 720 730 740 750
960 970 980 990 1000 1010
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
760 770 780 790 800 810
1020 1030 1040 1050 1060 1070
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
820 830 840 850 860 870
1080 1090 1100 1110 1120 1130
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
880 890 900 910 920 930
1140 1150 1160 1170 1180 1190
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
940 950 960 970 980
>>XP_005264491 (OMIM: 604475) PREDICTED: reticulon-4 iso (986 aa)
initn: 6195 init1: 6195 opt: 6195 Z-score: 2359.0 bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)
180 190 200 210 220 230
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
::::::::::::::::::::::::::::::
XP_005 MDLKEQPGNTISAGQEDFPSVLLETAASLP
10 20 30
240 250 260 270 280 290
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
40 50 60 70 80 90
300 310 320 330 340 350
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
100 110 120 130 140 150
360 370 380 390 400 410
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
160 170 180 190 200 210
420 430 440 450 460 470
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
220 230 240 250 260 270
480 490 500 510 520 530
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
280 290 300 310 320 330
540 550 560 570 580 590
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
340 350 360 370 380 390
600 610 620 630 640 650
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
400 410 420 430 440 450
660 670 680 690 700 710
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
460 470 480 490 500 510
720 730 740 750 760 770
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
520 530 540 550 560 570
780 790 800 810 820 830
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
580 590 600 610 620 630
840 850 860 870 880 890
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
640 650 660 670 680 690
900 910 920 930 940 950
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
700 710 720 730 740 750
960 970 980 990 1000 1010
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
760 770 780 790 800 810
1020 1030 1040 1050 1060 1070
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
820 830 840 850 860 870
1080 1090 1100 1110 1120 1130
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
880 890 900 910 920 930
1140 1150 1160 1170 1180 1190
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
940 950 960 970 980
>>NP_001308788 (OMIM: 604475) reticulon-4 isoform E [Hom (986 aa)
initn: 6195 init1: 6195 opt: 6195 Z-score: 2359.0 bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)
180 190 200 210 220 230
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
::::::::::::::::::::::::::::::
NP_001 MDLKEQPGNTISAGQEDFPSVLLETAASLP
10 20 30
240 250 260 270 280 290
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
40 50 60 70 80 90
300 310 320 330 340 350
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
100 110 120 130 140 150
360 370 380 390 400 410
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
160 170 180 190 200 210
420 430 440 450 460 470
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
220 230 240 250 260 270
480 490 500 510 520 530
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
280 290 300 310 320 330
540 550 560 570 580 590
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
340 350 360 370 380 390
600 610 620 630 640 650
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
400 410 420 430 440 450
660 670 680 690 700 710
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
460 470 480 490 500 510
720 730 740 750 760 770
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
520 530 540 550 560 570
780 790 800 810 820 830
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
580 590 600 610 620 630
840 850 860 870 880 890
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
640 650 660 670 680 690
900 910 920 930 940 950
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
700 710 720 730 740 750
960 970 980 990 1000 1010
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
760 770 780 790 800 810
1020 1030 1040 1050 1060 1070
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
820 830 840 850 860 870
1080 1090 1100 1110 1120 1130
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
880 890 900 910 920 930
1140 1150 1160 1170 1180 1190
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
940 950 960 970 980
>>NP_001308791 (OMIM: 604475) reticulon-4 isoform E [Hom (986 aa)
initn: 6195 init1: 6195 opt: 6195 Z-score: 2359.0 bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)
180 190 200 210 220 230
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
::::::::::::::::::::::::::::::
NP_001 MDLKEQPGNTISAGQEDFPSVLLETAASLP
10 20 30
240 250 260 270 280 290
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
40 50 60 70 80 90
300 310 320 330 340 350
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
100 110 120 130 140 150
360 370 380 390 400 410
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
160 170 180 190 200 210
420 430 440 450 460 470
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
220 230 240 250 260 270
480 490 500 510 520 530
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
280 290 300 310 320 330
540 550 560 570 580 590
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
340 350 360 370 380 390
600 610 620 630 640 650
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
400 410 420 430 440 450
660 670 680 690 700 710
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
460 470 480 490 500 510
720 730 740 750 760 770
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
520 530 540 550 560 570
780 790 800 810 820 830
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
580 590 600 610 620 630
840 850 860 870 880 890
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
640 650 660 670 680 690
900 910 920 930 940 950
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
700 710 720 730 740 750
960 970 980 990 1000 1010
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
760 770 780 790 800 810
1020 1030 1040 1050 1060 1070
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
820 830 840 850 860 870
1080 1090 1100 1110 1120 1130
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
880 890 900 910 920 930
1140 1150 1160 1170 1180 1190
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
940 950 960 970 980
>>XP_016860007 (OMIM: 604475) PREDICTED: reticulon-4 iso (986 aa)
initn: 6195 init1: 6195 opt: 6195 Z-score: 2359.0 bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)
180 190 200 210 220 230
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
::::::::::::::::::::::::::::::
XP_016 MDLKEQPGNTISAGQEDFPSVLLETAASLP
10 20 30
240 250 260 270 280 290
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
40 50 60 70 80 90
300 310 320 330 340 350
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
100 110 120 130 140 150
360 370 380 390 400 410
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
160 170 180 190 200 210
420 430 440 450 460 470
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
220 230 240 250 260 270
480 490 500 510 520 530
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
280 290 300 310 320 330
540 550 560 570 580 590
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
340 350 360 370 380 390
600 610 620 630 640 650
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
400 410 420 430 440 450
660 670 680 690 700 710
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
460 470 480 490 500 510
720 730 740 750 760 770
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
520 530 540 550 560 570
780 790 800 810 820 830
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
580 590 600 610 620 630
840 850 860 870 880 890
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
640 650 660 670 680 690
900 910 920 930 940 950
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
700 710 720 730 740 750
960 970 980 990 1000 1010
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
760 770 780 790 800 810
1020 1030 1040 1050 1060 1070
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
820 830 840 850 860 870
1080 1090 1100 1110 1120 1130
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
880 890 900 910 920 930
1140 1150 1160 1170 1180 1190
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
940 950 960 970 980
>>NP_001308833 (OMIM: 604475) reticulon-4 isoform E [Hom (986 aa)
initn: 6195 init1: 6195 opt: 6195 Z-score: 2359.0 bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)
180 190 200 210 220 230
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
::::::::::::::::::::::::::::::
NP_001 MDLKEQPGNTISAGQEDFPSVLLETAASLP
10 20 30
240 250 260 270 280 290
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
40 50 60 70 80 90
300 310 320 330 340 350
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
100 110 120 130 140 150
360 370 380 390 400 410
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
160 170 180 190 200 210
420 430 440 450 460 470
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
220 230 240 250 260 270
480 490 500 510 520 530
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
280 290 300 310 320 330
540 550 560 570 580 590
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
340 350 360 370 380 390
600 610 620 630 640 650
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
400 410 420 430 440 450
660 670 680 690 700 710
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
460 470 480 490 500 510
720 730 740 750 760 770
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
520 530 540 550 560 570
780 790 800 810 820 830
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
580 590 600 610 620 630
840 850 860 870 880 890
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
640 650 660 670 680 690
900 910 920 930 940 950
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
700 710 720 730 740 750
960 970 980 990 1000 1010
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
760 770 780 790 800 810
1020 1030 1040 1050 1060 1070
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
820 830 840 850 860 870
1080 1090 1100 1110 1120 1130
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
880 890 900 910 920 930
1140 1150 1160 1170 1180 1190
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
940 950 960 970 980
>>XP_016860008 (OMIM: 604475) PREDICTED: reticulon-4 iso (986 aa)
initn: 6195 init1: 6195 opt: 6195 Z-score: 2359.0 bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)
180 190 200 210 220 230
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
::::::::::::::::::::::::::::::
XP_016 MDLKEQPGNTISAGQEDFPSVLLETAASLP
10 20 30
240 250 260 270 280 290
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
40 50 60 70 80 90
300 310 320 330 340 350
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
100 110 120 130 140 150
360 370 380 390 400 410
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
160 170 180 190 200 210
420 430 440 450 460 470
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
220 230 240 250 260 270
480 490 500 510 520 530
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
280 290 300 310 320 330
540 550 560 570 580 590
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
340 350 360 370 380 390
600 610 620 630 640 650
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
400 410 420 430 440 450
660 670 680 690 700 710
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
460 470 480 490 500 510
720 730 740 750 760 770
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
520 530 540 550 560 570
780 790 800 810 820 830
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
580 590 600 610 620 630
840 850 860 870 880 890
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
640 650 660 670 680 690
900 910 920 930 940 950
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
700 710 720 730 740 750
960 970 980 990 1000 1010
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
760 770 780 790 800 810
1020 1030 1040 1050 1060 1070
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
820 830 840 850 860 870
1080 1090 1100 1110 1120 1130
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
880 890 900 910 920 930
1140 1150 1160 1170 1180 1190
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
940 950 960 970 980
>>NP_001308789 (OMIM: 604475) reticulon-4 isoform E [Hom (986 aa)
initn: 6195 init1: 6195 opt: 6195 Z-score: 2359.0 bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)
180 190 200 210 220 230
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
::::::::::::::::::::::::::::::
NP_001 MDLKEQPGNTISAGQEDFPSVLLETAASLP
10 20 30
240 250 260 270 280 290
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
40 50 60 70 80 90
300 310 320 330 340 350
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
100 110 120 130 140 150
360 370 380 390 400 410
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
160 170 180 190 200 210
420 430 440 450 460 470
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
220 230 240 250 260 270
480 490 500 510 520 530
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
280 290 300 310 320 330
540 550 560 570 580 590
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
340 350 360 370 380 390
600 610 620 630 640 650
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
400 410 420 430 440 450
660 670 680 690 700 710
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
460 470 480 490 500 510
720 730 740 750 760 770
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
520 530 540 550 560 570
780 790 800 810 820 830
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
580 590 600 610 620 630
840 850 860 870 880 890
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
640 650 660 670 680 690
900 910 920 930 940 950
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
700 710 720 730 740 750
960 970 980 990 1000 1010
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
760 770 780 790 800 810
1020 1030 1040 1050 1060 1070
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
820 830 840 850 860 870
1080 1090 1100 1110 1120 1130
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
880 890 900 910 920 930
1140 1150 1160 1170 1180 1190
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
940 950 960 970 980
>>NP_001308792 (OMIM: 604475) reticulon-4 isoform E [Hom (986 aa)
initn: 6195 init1: 6195 opt: 6195 Z-score: 2359.0 bits: 448.2 E(85289): 1.2e-124
Smith-Waterman score: 6195; 100.0% identity (100.0% similar) in 986 aa overlap (207-1192:1-986)
180 190 200 210 220 230
pF1KSD KRRGSSGSVDETLFALPAASEPVIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLP
::::::::::::::::::::::::::::::
NP_001 MDLKEQPGNTISAGQEDFPSVLLETAASLP
10 20 30
240 250 260 270 280 290
pF1KSD SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSPLSAASFKEHEYLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE
40 50 60 70 80 90
300 310 320 330 340 350
pF1KSD YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSEMGSSFSVSPKAESAVIVANPREEIIVKNKDEEEKLVSNNILHNQQELPTALTKLVKE
100 110 120 130 140 150
360 370 380 390 400 410
pF1KSD DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEVVSSEKAKDSFNEKRVAVEAPMREEYADFKPFERVWEVKDSKEDSDMLAAGGKIESNL
160 170 180 190 200 210
420 430 440 450 460 470
pF1KSD ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKVDKKCFADSLEQTNHEKDSESSNDDTSFPSTPEGIKDRSGAYITCAPFNPAATESIA
220 230 240 250 260 270
480 490 500 510 520 530
pF1KSD TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNIFPLLGDPTSENKTDEKKIEEKKAQIVTEKNTSTKTSNPFLVAAQDSETDYVTTDNLT
280 290 300 310 320 330
540 550 560 570 580 590
pF1KSD KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTEEVVANMPEGLTPDLVQEACESELNEVTGTKIAYETKMDLVQTSEVMQESLYPAAQL
340 350 360 370 380 390
600 610 620 630 640 650
pF1KSD CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPSFEESEATPSPVLPDIVMEAPLNSAVPSAGASVIQPSSSPLEASSVNYESIKHEPENP
400 410 420 430 440 450
660 670 680 690 700 710
pF1KSD PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPYEEAMSVSLKKVSGIKEEIKEPENINAALQETEAPYISIACDLIKETKLSAEPAPDFS
460 470 480 490 500 510
720 730 740 750 760 770
pF1KSD DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYSEMAKVEQPVPDHSELVEDSSPDSEPVDLFSDDSIPDVPQKQDETVMLVKESLTETSF
520 530 540 550 560 570
780 790 800 810 820 830
pF1KSD ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESMIEYENKEKLSALPPEGGKPYLESFKLSLDNTKDTLLPDEVSTLSKKEKIPLQMEELS
580 590 600 610 620 630
840 850 860 870 880 890
pF1KSD TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVYSNDDLFISKEAQIRETETFSDSSPIEIIDEFPTLISSKTDSFSKLAREYTDLEVSH
640 650 660 670 680 690
900 910 920 930 940 950
pF1KSD KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEIANAPDGAGSLPCTELPHDLSLKNIQPKVEEKISFSDDFSKNGSATSKVLLLPPDVS
700 710 720 730 740 750
960 970 980 990 1000 1010
pF1KSD ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALATQAEIESIVKPKVLVKEAEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKK
760 770 780 790 800 810
1020 1030 1040 1050 1060 1070
pF1KSD TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAY
820 830 840 850 860 870
1080 1090 1100 1110 1120 1130
pF1KSD LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFN
880 890 900 910 920 930
1140 1150 1160 1170 1180 1190
pF1KSD GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE
940 950 960 970 980
1192 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 03:58:05 2016 done: Thu Nov 3 03:58:07 2016
Total Scan time: 14.280 Total Display time: 0.380
Function used was FASTA [36.3.4 Apr, 2011]