Result of FASTA (omim) for
pFN21ASDA0794
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0794, 489 aa
1>>>pF1KSDA0794 489 - 489 aa - 489 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0361+/-0.000358; mu= 10.0020+/- 0.022
mean_var=105.9665+/-21.027, 0's: 0 Z-trim(116.4): 17 B-trim: 158 in 1/54
Lambda= 0.124592
statistics sampled from 27573 (27588) to 27573 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.323), width: 16
Scan time: 9.170
The best scores are: opt bits E(85289)
NP_056377 (OMIM: 616379) UBX domain-containing pro ( 489) 3262 597.0 3.8e-170
XP_011510972 (OMIM: 616379) PREDICTED: UBX domain- ( 456) 3060 560.7 3.1e-159
XP_011510973 (OMIM: 616379) PREDICTED: UBX domain- ( 341) 2304 424.8 1.9e-118
XP_016855625 (OMIM: 604460) PREDICTED: FAS-associa ( 541) 203 47.2 0.00014
NP_008982 (OMIM: 604460) FAS-associated factor 1 [ ( 650) 203 47.2 0.00016
>>NP_056377 (OMIM: 616379) UBX domain-containing protein (489 aa)
initn: 3262 init1: 3262 opt: 3262 Z-score: 3175.6 bits: 597.0 E(85289): 3.8e-170
Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 489 aa overlap (1-489:1-489)
10 20 30 40 50 60
pF1KSD MAAHGGSAASSALKGLIQQFTTITGASESVGKHMLEACNNNLEMAVTMFLDGGGIAEEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MAAHGGSAASSALKGLIQQFTTITGASESVGKHMLEACNNNLEMAVTMFLDGGGIAEEPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD TSSASVSTVRPHTEEEVRAPIPQKQEILVEPEPLFGAPKRRRPARSIFDGFRDFQTETIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TSSASVSTVRPHTEEEVRAPIPQKQEILVEPEPLFGAPKRRRPARSIFDGFRDFQTETIR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QEQELRNGGAIDKKLTTLADLFRPPIDLMHKGSFETAKECGQMQNKWLMINIQNVQDFAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QEQELRNGGAIDKKLTTLADLFRPPIDLMHKGSFETAKECGQMQNKWLMINIQNVQDFAC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD QCLNRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLGDFPYVSILDPRTGQKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QCLNRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLGDFPYVSILDPRTGQKLV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD EWHQLDVSSFLDQVTGFLGEHGQLDGLSSSPPKKCARSESLIDASEDSQLEAAIRASLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EWHQLDVSSFLDQVTGFLGEHGQLDGLSSSPPKKCARSESLIDASEDSQLEAAIRASLQE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD THFDSTQTKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 THFDSTQTKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHRKE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD ENRRPLTEPPVRTDPGTATNHQGLPAVDSEILEMPPEKADGVVEGIDVNGPKAQLMLRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ENRRPLTEPPVRTDPGTATNHQGLPAVDSEILEMPPEKADGVVEGIDVNGPKAQLMLRYP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD DGKREQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQEAGLCPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DGKREQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQEAGLCPQ
430 440 450 460 470 480
pF1KSD ETVFVQERN
:::::::::
NP_056 ETVFVQERN
>>XP_011510972 (OMIM: 616379) PREDICTED: UBX domain-cont (456 aa)
initn: 3060 init1: 3060 opt: 3060 Z-score: 2979.8 bits: 560.7 E(85289): 3.1e-159
Smith-Waterman score: 3060; 100.0% identity (100.0% similar) in 456 aa overlap (34-489:1-456)
10 20 30 40 50 60
pF1KSD HGGSAASSALKGLIQQFTTITGASESVGKHMLEACNNNLEMAVTMFLDGGGIAEEPSTSS
::::::::::::::::::::::::::::::
XP_011 MLEACNNNLEMAVTMFLDGGGIAEEPSTSS
10 20 30
70 80 90 100 110 120
pF1KSD ASVSTVRPHTEEEVRAPIPQKQEILVEPEPLFGAPKRRRPARSIFDGFRDFQTETIRQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASVSTVRPHTEEEVRAPIPQKQEILVEPEPLFGAPKRRRPARSIFDGFRDFQTETIRQEQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KSD ELRNGGAIDKKLTTLADLFRPPIDLMHKGSFETAKECGQMQNKWLMINIQNVQDFACQCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELRNGGAIDKKLTTLADLFRPPIDLMHKGSFETAKECGQMQNKWLMINIQNVQDFACQCL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KSD NRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLGDFPYVSILDPRTGQKLVEWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLGDFPYVSILDPRTGQKLVEWH
160 170 180 190 200 210
250 260 270 280 290 300
pF1KSD QLDVSSFLDQVTGFLGEHGQLDGLSSSPPKKCARSESLIDASEDSQLEAAIRASLQETHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDVSSFLDQVTGFLGEHGQLDGLSSSPPKKCARSESLIDASEDSQLEAAIRASLQETHF
220 230 240 250 260 270
310 320 330 340 350 360
pF1KSD DSTQTKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHRKEENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSTQTKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHRKEENR
280 290 300 310 320 330
370 380 390 400 410 420
pF1KSD RPLTEPPVRTDPGTATNHQGLPAVDSEILEMPPEKADGVVEGIDVNGPKAQLMLRYPDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPLTEPPVRTDPGTATNHQGLPAVDSEILEMPPEKADGVVEGIDVNGPKAQLMLRYPDGK
340 350 360 370 380 390
430 440 450 460 470 480
pF1KSD REQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQEAGLCPQETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQEAGLCPQETV
400 410 420 430 440 450
pF1KSD FVQERN
::::::
XP_011 FVQERN
>>XP_011510973 (OMIM: 616379) PREDICTED: UBX domain-cont (341 aa)
initn: 2304 init1: 2304 opt: 2304 Z-score: 2247.4 bits: 424.8 E(85289): 1.9e-118
Smith-Waterman score: 2304; 100.0% identity (100.0% similar) in 341 aa overlap (149-489:1-341)
120 130 140 150 160 170
pF1KSD IRQEQELRNGGAIDKKLTTLADLFRPPIDLMHKGSFETAKECGQMQNKWLMINIQNVQDF
::::::::::::::::::::::::::::::
XP_011 MHKGSFETAKECGQMQNKWLMINIQNVQDF
10 20 30
180 190 200 210 220 230
pF1KSD ACQCLNRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLGDFPYVSILDPRTGQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACQCLNRDVWSNEAVKNIIREHFIFWQVYHDSEEGQRYIQFYKLGDFPYVSILDPRTGQK
40 50 60 70 80 90
240 250 260 270 280 290
pF1KSD LVEWHQLDVSSFLDQVTGFLGEHGQLDGLSSSPPKKCARSESLIDASEDSQLEAAIRASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVEWHQLDVSSFLDQVTGFLGEHGQLDGLSSSPPKKCARSESLIDASEDSQLEAAIRASL
100 110 120 130 140 150
300 310 320 330 340 350
pF1KSD QETHFDSTQTKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QETHFDSTQTKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKSRKSPHKDLGHR
160 170 180 190 200 210
360 370 380 390 400 410
pF1KSD KEENRRPLTEPPVRTDPGTATNHQGLPAVDSEILEMPPEKADGVVEGIDVNGPKAQLMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEENRRPLTEPPVRTDPGTATNHQGLPAVDSEILEMPPEKADGVVEGIDVNGPKAQLMLR
220 230 240 250 260 270
420 430 440 450 460 470
pF1KSD YPDGKREQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQEAGLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPDGKREQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLSHLDYDITLQEAGLC
280 290 300 310 320 330
480
pF1KSD PQETVFVQERN
:::::::::::
XP_011 PQETVFVQERN
340
>>XP_016855625 (OMIM: 604460) PREDICTED: FAS-associated (541 aa)
initn: 226 init1: 156 opt: 203 Z-score: 203.3 bits: 47.2 E(85289): 0.00014
Smith-Waterman score: 203; 27.6% identity (58.6% similar) in 174 aa overlap (321-488:376-540)
300 310 320 330 340
pF1KSD EAAIRASLQETHFDSTQTKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKS---
:.:..... .. ::.: ::. .
XP_016 MGKRSSNEVLNVIQGNTTVDELMMRLMAAMEIFTAQQQE-DIKDEDEREARENVKREQDE
350 360 370 380 390 400
350 360 370 380 390 400
pF1KSD --RKSPHKDLGHRKEENRRPLTEPPVRTDPGTATNHQGLPAVDSEILE-MPPEKADGVVE
: : . : ..: : ..: ..: : . ... :. . . .::: . .:
XP_016 AYRLSLEADRAKR-EAHEREMAEQ-FRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAE
410 420 430 440 450 460
410 420 430 440 450 460
pF1KSD GIDVNGPKAQLMLRYPDGKREQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLS
: ..: .: :.:. . . . :: . : :::.: ....::..:::: ..
XP_016 ------PVSKLRIRTPSGEFLERRFLASNKLQIVFDFVASKGFPWDEYKLLSTFPRRDVT
470 480 490 500 510
470 480
pF1KSD HLDYDITLQEAGLCPQETVFVQERN
.:: . .: :. : ::::.:.. .
XP_016 QLDPNKSLLEVKLFPQETLFLEAKE
520 530 540
>>NP_008982 (OMIM: 604460) FAS-associated factor 1 [Homo (650 aa)
initn: 226 init1: 156 opt: 203 Z-score: 202.0 bits: 47.2 E(85289): 0.00016
Smith-Waterman score: 203; 27.6% identity (58.6% similar) in 174 aa overlap (321-488:485-649)
300 310 320 330 340
pF1KSD EAAIRASLQETHFDSTQTKQDSRSDEESESELFSGSEEFISVCGSDEEEEVENLAKS---
:.:..... .. ::.: ::. .
NP_008 MGKRSSNEVLNVIQGNTTVDELMMRLMAAMEIFTAQQQE-DIKDEDEREARENVKREQDE
460 470 480 490 500 510
350 360 370 380 390 400
pF1KSD --RKSPHKDLGHRKEENRRPLTEPPVRTDPGTATNHQGLPAVDSEILE-MPPEKADGVVE
: : . : ..: : ..: ..: : . ... :. . . .::: . .:
NP_008 AYRLSLEADRAKR-EAHEREMAEQ-FRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAE
520 530 540 550 560 570
410 420 430 440 450 460
pF1KSD GIDVNGPKAQLMLRYPDGKREQITLPEQAKLLALVKHVQSKGYPNERFELLTNFPRRKLS
: ..: .: :.:. . . . :: . : :::.: ....::..:::: ..
NP_008 ------PVSKLRIRTPSGEFLERRFLASNKLQIVFDFVASKGFPWDEYKLLSTFPRRDVT
580 590 600 610 620
470 480
pF1KSD HLDYDITLQEAGLCPQETVFVQERN
.:: . .: :. : ::::.:.. .
NP_008 QLDPNKSLLEVKLFPQETLFLEAKE
630 640 650
489 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 03:11:53 2016 done: Thu Nov 3 03:11:54 2016
Total Scan time: 9.170 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]