Result of FASTA (omim) for
pFN21ASDA0696
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0696, 542 aa
1>>>pF1KSDA0696 542 - 542 aa - 542 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3133+/-0.000547; mu= 13.6991+/- 0.033
mean_var=184.5930+/-41.392, 0's: 0 Z-trim(111.2): 330 B-trim: 81 in 1/53
Lambda= 0.094399
statistics sampled from 19354 (19739) to 19354 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.585), E-opt: 0.2 (0.231), width: 16
Scan time: 6.690
The best scores are: opt bits E(85289)
NP_036432 (OMIM: 605651) F-box/WD repeat-containin ( 542) 3696 517.2 5.1e-146
XP_016864770 (OMIM: 605651) PREDICTED: F-box/WD re ( 510) 3478 487.5 4.3e-137
XP_016864769 (OMIM: 605651) PREDICTED: F-box/WD re ( 510) 3361 471.5 2.7e-132
XP_005265915 (OMIM: 605651) PREDICTED: F-box/WD re ( 510) 3361 471.5 2.7e-132
XP_005265914 (OMIM: 605651) PREDICTED: F-box/WD re ( 515) 3361 471.5 2.7e-132
NP_387448 (OMIM: 605651) F-box/WD repeat-containin ( 529) 3361 471.5 2.7e-132
XP_005265913 (OMIM: 605651) PREDICTED: F-box/WD re ( 531) 3361 471.5 2.8e-132
XP_016864768 (OMIM: 605651) PREDICTED: F-box/WD re ( 542) 3361 471.6 2.8e-132
XP_005265912 (OMIM: 605651) PREDICTED: F-box/WD re ( 563) 3361 471.6 2.9e-132
NP_387449 (OMIM: 605651) F-box/WD repeat-containin ( 508) 3359 471.3 3.2e-132
XP_016872363 (OMIM: 603482) PREDICTED: F-box/WD re ( 543) 3058 430.3 7.4e-120
NP_003930 (OMIM: 603482) F-box/WD repeat-containin ( 569) 3049 429.1 1.8e-119
XP_016872362 (OMIM: 603482) PREDICTED: F-box/WD re ( 587) 3049 429.1 1.8e-119
XP_016872361 (OMIM: 603482) PREDICTED: F-box/WD re ( 587) 3049 429.1 1.8e-119
XP_016872360 (OMIM: 603482) PREDICTED: F-box/WD re ( 587) 3049 429.1 1.8e-119
NP_378663 (OMIM: 603482) F-box/WD repeat-containin ( 605) 3049 429.1 1.8e-119
XP_006718117 (OMIM: 603482) PREDICTED: F-box/WD re ( 732) 3049 429.2 2.1e-119
NP_001243785 (OMIM: 603482) F-box/WD repeat-contai ( 579) 3045 428.6 2.6e-119
XP_016872359 (OMIM: 603482) PREDICTED: F-box/WD re ( 706) 3045 428.7 2.9e-119
XP_011538622 (OMIM: 603482) PREDICTED: F-box/WD re ( 537) 3026 425.9 1.5e-118
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540) 411 69.8 2.4e-11
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589) 411 69.9 2.6e-11
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627) 411 69.9 2.7e-11
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 411 69.9 2.8e-11
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 411 69.9 2.8e-11
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 411 70.0 2.8e-11
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 411 70.0 2.8e-11
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 411 70.0 2.8e-11
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707) 411 70.0 2.8e-11
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 411 70.0 2.8e-11
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 370 63.9 8.7e-10
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 370 63.9 8.7e-10
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 370 63.9 8.7e-10
NP_004757 (OMIM: 606990) coatomer subunit beta' [H ( 906) 369 64.4 1.7e-09
NP_008882 (OMIM: 601787) transcription initiation ( 800) 358 62.8 4.6e-09
XP_016863001 (OMIM: 606990) PREDICTED: coatomer su ( 877) 357 62.7 5.3e-09
XP_011521928 (OMIM: 611679) PREDICTED: F-box/WD re ( 745) 354 62.2 6.4e-09
XP_016879510 (OMIM: 611679) PREDICTED: F-box/WD re ( 724) 349 61.5 1e-08
XP_011521927 (OMIM: 611679) PREDICTED: F-box/WD re ( 856) 349 61.6 1.1e-08
XP_016879509 (OMIM: 611679) PREDICTED: F-box/WD re ( 856) 349 61.6 1.1e-08
NP_006373 (OMIM: 604596) CMT1A duplicated region t ( 752) 348 61.4 1.1e-08
NP_001254514 (OMIM: 611679) F-box/WD repeat-contai (1052) 349 61.7 1.3e-08
NP_001269469 (OMIM: 604596) CMT1A duplicated regio ( 714) 346 61.1 1.3e-08
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 341 60.1 1.4e-08
XP_016856549 (OMIM: 139380,613065,616973) PREDICTE ( 340) 330 58.5 3.9e-08
NP_001269468 (OMIM: 139380,613065,616973) guanine ( 340) 330 58.5 3.9e-08
XP_016856548 (OMIM: 139380,613065,616973) PREDICTE ( 340) 330 58.5 3.9e-08
NP_002065 (OMIM: 139380,613065,616973) guanine nuc ( 340) 330 58.5 3.9e-08
XP_016856550 (OMIM: 139380,613065,616973) PREDICTE ( 340) 330 58.5 3.9e-08
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 332 59.2 4.7e-08
>>NP_036432 (OMIM: 605651) F-box/WD repeat-containing pr (542 aa)
initn: 3696 init1: 3696 opt: 3696 Z-score: 2742.4 bits: 517.2 E(85289): 5.1e-146
Smith-Waterman score: 3696; 100.0% identity (100.0% similar) in 542 aa overlap (1-542:1-542)
10 20 30 40 50 60
pF1KSD MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQISNGTSSVIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQISNGTSSVIVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD TALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD KGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD STLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 STLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYI
490 500 510 520 530 540
pF1KSD SR
::
NP_036 SR
>>XP_016864770 (OMIM: 605651) PREDICTED: F-box/WD repeat (510 aa)
initn: 3478 init1: 3478 opt: 3478 Z-score: 2582.3 bits: 487.5 E(85289): 4.3e-137
Smith-Waterman score: 3478; 100.0% identity (100.0% similar) in 510 aa overlap (33-542:1-510)
10 20 30 40 50 60
pF1KSD PDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQISNGTSSVIVSRK
::::::::::::::::::::::::::::::
XP_016 MCALSCLQSMPSVRCLQISNGTSSVIVSRK
10 20 30
70 80 90 100 110 120
pF1KSD RPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KSD LPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KSD ERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KSD VYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KSD RVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGH
280 290 300 310 320 330
370 380 390 400 410 420
pF1KSD RAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSD
340 350 360 370 380 390
430 440 450 460 470 480
pF1KSD NTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPAST
400 410 420 430 440 450
490 500 510 520 530 540
pF1KSD LCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR
460 470 480 490 500 510
>>XP_016864769 (OMIM: 605651) PREDICTED: F-box/WD repeat (510 aa)
initn: 3361 init1: 3361 opt: 3361 Z-score: 2496.1 bits: 471.5 E(85289): 2.7e-132
Smith-Waterman score: 3361; 100.0% identity (100.0% similar) in 494 aa overlap (49-542:17-510)
20 30 40 50 60 70
pF1KSD PRSLWLGCANLVESMCALSCLQSMPSVRCLQISNGTSSVIVSRKRPSEGNYQKEKDLCIK
::::::::::::::::::::::::::::::
XP_016 MEDQNEDESPKKNTLWQISNGTSSVIVSRKRPSEGNYQKEKDLCIK
10 20 30 40
80 90 100 110 120 130
pF1KSD YFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSY
50 60 70 80 90 100
140 150 160 170 180 190
pF1KSD LDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTD
110 120 130 140 150 160
200 210 220 230 240 250
pF1KSD GPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLR
170 180 190 200 210 220
260 270 280 290 300 310
pF1KSD DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIH
230 240 250 260 270 280
320 330 340 350 360 370
pF1KSD HNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS
290 300 310 320 330 340
380 390 400 410 420 430
pF1KSD ASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRV
350 360 370 380 390 400
440 450 460 470 480 490
pF1KSD LEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL
410 420 430 440 450 460
500 510 520 530 540
pF1KSD QFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR
::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR
470 480 490 500 510
>>XP_005265915 (OMIM: 605651) PREDICTED: F-box/WD repeat (510 aa)
initn: 3361 init1: 3361 opt: 3361 Z-score: 2496.1 bits: 471.5 E(85289): 2.7e-132
Smith-Waterman score: 3361; 100.0% identity (100.0% similar) in 494 aa overlap (49-542:17-510)
20 30 40 50 60 70
pF1KSD PRSLWLGCANLVESMCALSCLQSMPSVRCLQISNGTSSVIVSRKRPSEGNYQKEKDLCIK
::::::::::::::::::::::::::::::
XP_005 MEDQNEDESPKKNTLWQISNGTSSVIVSRKRPSEGNYQKEKDLCIK
10 20 30 40
80 90 100 110 120 130
pF1KSD YFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSY
50 60 70 80 90 100
140 150 160 170 180 190
pF1KSD LDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTD
110 120 130 140 150 160
200 210 220 230 240 250
pF1KSD GPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLR
170 180 190 200 210 220
260 270 280 290 300 310
pF1KSD DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIH
230 240 250 260 270 280
320 330 340 350 360 370
pF1KSD HNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS
290 300 310 320 330 340
380 390 400 410 420 430
pF1KSD ASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRV
350 360 370 380 390 400
440 450 460 470 480 490
pF1KSD LEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL
410 420 430 440 450 460
500 510 520 530 540
pF1KSD QFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR
::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR
470 480 490 500 510
>>XP_005265914 (OMIM: 605651) PREDICTED: F-box/WD repeat (515 aa)
initn: 3361 init1: 3361 opt: 3361 Z-score: 2496.1 bits: 471.5 E(85289): 2.7e-132
Smith-Waterman score: 3361; 100.0% identity (100.0% similar) in 494 aa overlap (49-542:22-515)
20 30 40 50 60 70
pF1KSD PRSLWLGCANLVESMCALSCLQSMPSVRCLQISNGTSSVIVSRKRPSEGNYQKEKDLCIK
::::::::::::::::::::::::::::::
XP_005 MNTSVMEDQNEDESPKKNTLWQISNGTSSVIVSRKRPSEGNYQKEKDLCIK
10 20 30 40 50
80 90 100 110 120 130
pF1KSD YFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSY
60 70 80 90 100 110
140 150 160 170 180 190
pF1KSD LDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTD
120 130 140 150 160 170
200 210 220 230 240 250
pF1KSD GPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLR
180 190 200 210 220 230
260 270 280 290 300 310
pF1KSD DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIH
240 250 260 270 280 290
320 330 340 350 360 370
pF1KSD HNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS
300 310 320 330 340 350
380 390 400 410 420 430
pF1KSD ASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRV
360 370 380 390 400 410
440 450 460 470 480 490
pF1KSD LEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL
420 430 440 450 460 470
500 510 520 530 540
pF1KSD QFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR
::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR
480 490 500 510
>>NP_387448 (OMIM: 605651) F-box/WD repeat-containing pr (529 aa)
initn: 3441 init1: 3361 opt: 3361 Z-score: 2496.0 bits: 471.5 E(85289): 2.7e-132
Smith-Waterman score: 3408; 94.3% identity (95.8% similar) in 543 aa overlap (1-542:1-529)
10 20 30 40 50
pF1KSD MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCL-QISNGTSSVIV
::::::::::::::: . ...:.. . :. : :::::::::::
NP_387 MEPDSVIEDKTIELMNT----------SVMEDQNE----DESPKKNTLWQISNGTSSVIV
10 20 30 40
60 70 80 90 100 110
pF1KSD SRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 SRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KSD ITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 ITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWK
110 120 130 140 150 160
180 190 200 210 220 230
pF1KSD GLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 GLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSEN
170 180 190 200 210 220
240 250 260 270 280 290
pF1KSD SKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 SKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KSD STVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 STVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVL
290 300 310 320 330 340
360 370 380 390 400 410
pF1KSD VGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 VGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSG
350 360 370 380 390 400
420 430 440 450 460 470
pF1KSD SSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 SSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAP
410 420 430 440 450 460
480 490 500 510 520 530
pF1KSD ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTY
470 480 490 500 510 520
540
pF1KSD ISR
:::
NP_387 ISR
>>XP_005265913 (OMIM: 605651) PREDICTED: F-box/WD repeat (531 aa)
initn: 3361 init1: 3361 opt: 3361 Z-score: 2495.9 bits: 471.5 E(85289): 2.8e-132
Smith-Waterman score: 3426; 96.0% identity (96.0% similar) in 531 aa overlap (33-542:1-531)
10 20 30 40
pF1KSD PDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQ-------------
:::::::::::::::::
XP_005 MCALSCLQSMPSVRCLQNTSVMEDQNEDES
10 20 30
50 60 70 80 90 100
pF1KSD --------ISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCH
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKKNTLWQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCH
40 50 60 70 80 90
110 120 130 140 150 160
pF1KSD YQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEG
100 110 120 130 140 150
170 180 190 200 210 220
pF1KSD MLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIES
160 170 180 190 200 210
230 240 250 260 270 280
pF1KSD NWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTG
220 230 240 250 260 270
290 300 310 320 330 340
pF1KSD SVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRS
280 290 300 310 320 330
350 360 370 380 390 400
pF1KSD IAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNG
340 350 360 370 380 390
410 420 430 440 450 460
pF1KSD HKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAY
400 410 420 430 440 450
470 480 490 500 510 520
pF1KSD DGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLN
460 470 480 490 500 510
530 540
pF1KSD VPPSAQNETRSPSRTYTYISR
:::::::::::::::::::::
XP_005 VPPSAQNETRSPSRTYTYISR
520 530
>>XP_016864768 (OMIM: 605651) PREDICTED: F-box/WD repeat (542 aa)
initn: 3361 init1: 3361 opt: 3361 Z-score: 2495.9 bits: 471.6 E(85289): 2.8e-132
Smith-Waterman score: 3361; 100.0% identity (100.0% similar) in 494 aa overlap (49-542:49-542)
20 30 40 50 60 70
pF1KSD PRSLWLGCANLVESMCALSCLQSMPSVRCLQISNGTSSVIVSRKRPSEGNYQKEKDLCIK
::::::::::::::::::::::::::::::
XP_016 ISWISKFDQENTSVMEDQNEDESPKKNTLWQISNGTSSVIVSRKRPSEGNYQKEKDLCIK
20 30 40 50 60 70
80 90 100 110 120 130
pF1KSD YFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSY
80 90 100 110 120 130
140 150 160 170 180 190
pF1KSD LDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTD
140 150 160 170 180 190
200 210 220 230 240 250
pF1KSD GPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLR
200 210 220 230 240 250
260 270 280 290 300 310
pF1KSD DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIH
260 270 280 290 300 310
320 330 340 350 360 370
pF1KSD HNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS
320 330 340 350 360 370
380 390 400 410 420 430
pF1KSD ASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRV
380 390 400 410 420 430
440 450 460 470 480 490
pF1KSD LEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRL
440 450 460 470 480 490
500 510 520 530 540
pF1KSD QFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR
::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR
500 510 520 530 540
>>XP_005265912 (OMIM: 605651) PREDICTED: F-box/WD repeat (563 aa)
initn: 3361 init1: 3361 opt: 3361 Z-score: 2495.7 bits: 471.6 E(85289): 2.9e-132
Smith-Waterman score: 3644; 96.3% identity (96.3% similar) in 563 aa overlap (1-542:1-563)
10 20 30 40
pF1KSD MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQ-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQNTSVMEDQNED
10 20 30 40 50 60
50 60 70 80 90
pF1KSD ----------ISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRM
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESPKKNTLWQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRM
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD CHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVIS
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD EGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETI
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD ESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGH
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD TGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD RSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD NGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSG
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD AYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDF
490 500 510 520 530 540
520 530 540
pF1KSD LNVPPSAQNETRSPSRTYTYISR
:::::::::::::::::::::::
XP_005 LNVPPSAQNETRSPSRTYTYISR
550 560
>>NP_387449 (OMIM: 605651) F-box/WD repeat-containing pr (508 aa)
initn: 3359 init1: 3359 opt: 3359 Z-score: 2494.7 bits: 471.3 E(85289): 3.2e-132
Smith-Waterman score: 3370; 93.7% identity (93.7% similar) in 542 aa overlap (1-542:1-508)
10 20 30 40 50 60
pF1KSD MEPDSVIEDKTIELMCSVPRSLWLGCANLVESMCALSCLQSMPSVRCLQISNGTSSVIVS
::::::::::::::: :::::::::::
NP_387 MEPDSVIEDKTIELM----------------------------------ISNGTSSVIVS
10 20
70 80 90 100 110 120
pF1KSD RKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 RKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFI
30 40 50 60 70 80
130 140 150 160 170 180
pF1KSD TALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 TALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKG
90 100 110 120 130 140
190 200 210 220 230 240
pF1KSD LSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 LSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENS
150 160 170 180 190 200
250 260 270 280 290 300
pF1KSD KGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 KGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDS
210 220 230 240 250 260
310 320 330 340 350 360
pF1KSD TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 TVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLV
270 280 290 300 310 320
370 380 390 400 410 420
pF1KSD GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 GHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGS
330 340 350 360 370 380
430 440 450 460 470 480
pF1KSD SDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 SDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPA
390 400 410 420 430 440
490 500 510 520 530 540
pF1KSD STLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_387 STLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYI
450 460 470 480 490 500
pF1KSD SR
::
NP_387 SR
542 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 02:44:14 2016 done: Thu Nov 3 02:44:15 2016
Total Scan time: 6.690 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]