Result of FASTA (omim) for
pFN21ASDA0362
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0362, 1096 aa
1>>>pF1KSDA0362 1096 - 1096 aa - 1096 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7412+/-0.000393; mu= 11.7990+/- 0.024
mean_var=166.4420+/-34.364, 0's: 0 Z-trim(117.3): 350 B-trim: 488 in 1/57
Lambda= 0.099413
statistics sampled from 28800 (29203) to 28800 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.688), E-opt: 0.2 (0.342), width: 16
Scan time: 14.610
The best scores are: opt bits E(85289)
XP_016875984 (OMIM: 609499) PREDICTED: guanine nuc (1182) 7330 1064.4 0
NP_079255 (OMIM: 609499) guanine nucleotide exchan (1123) 6881 1000.0 0
NP_001307745 (OMIM: 609499) guanine nucleotide exc (1129) 6870 998.4 0
NP_001106203 (OMIM: 609499) guanine nucleotide exc (1125) 6867 998.0 0
XP_016875986 (OMIM: 609499) PREDICTED: guanine nuc (1096) 6848 995.3 0
XP_016875982 (OMIM: 609499) PREDICTED: guanine nuc (1207) 6796 987.8 0
XP_011535788 (OMIM: 609499) PREDICTED: guanine nuc (1238) 6794 987.6 0
XP_016875988 (OMIM: 609499) PREDICTED: guanine nuc (1043) 6787 986.5 0
XP_016875987 (OMIM: 609499) PREDICTED: guanine nuc (1087) 6409 932.3 0
NP_001307744 (OMIM: 609499) guanine nucleotide exc (1148) 6347 923.4 0
XP_011535789 (OMIM: 609499) PREDICTED: guanine nuc (1179) 6345 923.2 0
NP_001307746 (OMIM: 609499) guanine nucleotide exc ( 984) 6338 922.1 0
XP_016875983 (OMIM: 609499) PREDICTED: guanine nuc (1187) 6336 921.9 0
XP_011535786 (OMIM: 609499) PREDICTED: guanine nuc (1185) 6334 921.6 0
XP_011535785 (OMIM: 609499) PREDICTED: guanine nuc (1211) 6334 921.6 0
XP_011535784 (OMIM: 609499) PREDICTED: guanine nuc (1211) 6334 921.6 0
XP_011535787 (OMIM: 609499) PREDICTED: guanine nuc (1181) 6331 921.1 0
XP_011535790 (OMIM: 609499) PREDICTED: guanine nuc (1163) 6329 920.9 0
XP_011535792 (OMIM: 609499) PREDICTED: guanine nuc (1152) 6312 918.4 0
XP_016875985 (OMIM: 609499) PREDICTED: guanine nuc (1112) 5875 855.7 0
XP_011535793 (OMIM: 609499) PREDICTED: guanine nuc (1143) 5873 855.4 0
NP_001093325 (OMIM: 311030) proto-oncogene DBL iso ( 985) 2855 422.5 5.8e-117
NP_005360 (OMIM: 311030) proto-oncogene DBL isofor ( 925) 2650 393.1 3.9e-108
NP_001165349 (OMIM: 311030) proto-oncogene DBL iso ( 860) 2601 386.1 4.8e-106
NP_001165348 (OMIM: 311030) proto-oncogene DBL iso ( 821) 2244 334.9 1.2e-90
XP_016885021 (OMIM: 311030) PREDICTED: proto-oncog ( 938) 1513 230.1 4.9e-59
NP_001165350 (OMIM: 311030) proto-oncogene DBL iso ( 941) 1513 230.1 4.9e-59
XP_016885020 (OMIM: 311030) PREDICTED: proto-oncog (1001) 1513 230.1 5.1e-59
XP_011529641 (OMIM: 311030) PREDICTED: proto-oncog (1001) 1513 230.1 5.1e-59
NP_001165347 (OMIM: 311030) proto-oncogene DBL iso (1001) 1513 230.1 5.1e-59
XP_016885018 (OMIM: 311030) PREDICTED: proto-oncog (1041) 1513 230.1 5.3e-59
XP_005262470 (OMIM: 311030) PREDICTED: proto-oncog (1044) 1513 230.1 5.3e-59
XP_016885019 (OMIM: 311030) PREDICTED: proto-oncog ( 979) 1464 223.0 6.6e-57
NP_891992 (OMIM: 610215) rho guanine nucleotide ex ( 580) 658 107.3 2.8e-22
NP_001104740 (OMIM: 610215) rho guanine nucleotide ( 619) 658 107.3 2.9e-22
XP_016865292 (OMIM: 601893,617061) PREDICTED: trip (2612) 636 104.6 7.8e-21
XP_011512412 (OMIM: 601893,617061) PREDICTED: trip (3038) 636 104.7 8.8e-21
XP_011512411 (OMIM: 601893,617061) PREDICTED: trip (3048) 636 104.7 8.8e-21
XP_011512410 (OMIM: 601893,617061) PREDICTED: trip (3058) 636 104.7 8.9e-21
XP_011512409 (OMIM: 601893,617061) PREDICTED: trip (3076) 636 104.7 8.9e-21
XP_016865291 (OMIM: 601893,617061) PREDICTED: trip (2880) 628 103.5 1.9e-20
XP_016865290 (OMIM: 601893,617061) PREDICTED: trip (3093) 628 103.5 2e-20
NP_009049 (OMIM: 601893,617061) triple functional (3097) 628 103.5 2e-20
NP_001309921 (OMIM: 604605,608901) kalirin isoform (1613) 603 99.7 1.4e-19
NP_001309920 (OMIM: 604605,608901) kalirin isoform (1641) 603 99.7 1.5e-19
XP_016862924 (OMIM: 604605,608901) PREDICTED: kali (1643) 603 99.7 1.5e-19
NP_001309919 (OMIM: 604605,608901) kalirin isoform (1650) 603 99.7 1.5e-19
XP_016862923 (OMIM: 604605,608901) PREDICTED: kali (1652) 603 99.7 1.5e-19
NP_001309918 (OMIM: 604605,608901) kalirin isoform (1654) 603 99.7 1.5e-19
XP_016862922 (OMIM: 604605,608901) PREDICTED: kali (1656) 603 99.7 1.5e-19
>>XP_016875984 (OMIM: 609499) PREDICTED: guanine nucleot (1182 aa)
initn: 7330 init1: 7330 opt: 7330 Z-score: 5688.4 bits: 1064.4 E(85289): 0
Smith-Waterman score: 7330; 100.0% identity (100.0% similar) in 1096 aa overlap (1-1096:25-1120)
10 20 30
pF1KSD MPLRGGAGPSPASHGPTHGPSDPRTCLPGRGAGGMR
::::::::::::::::::::::::::::::::::::
XP_016 MARVESPVPAARASLTGSCVLGQAMPLRGGAGPSPASHGPTHGPSDPRTCLPGRGAGGMR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD PHGRGALGCCGLCSFYTCHGAAGDEIMHQDIVPLCAADIQDQLKKRFAYLSGGRGQDGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHGRGALGCCGLCSFYTCHGAAGDEIMHQDIVPLCAADIQDQLKKRFAYLSGGRGQDGSP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD VITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASVLRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASVLRIA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD ASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQLT
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD EDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD HTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQLNETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQLNETE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD AAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEHLLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEHLLRD
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD LASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIARRRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIARRRGL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD LSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQE
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD LNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD ALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILRR
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD HVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHN
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD RIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRK
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD LDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMH
790 800 810 820 830 840
820 830 840 850 860 870
pF1KSD LIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCK
850 860 870 880 890 900
880 890 900 910 920 930
pF1KSD KREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIK
910 920 930 940 950 960
940 950 960 970 980 990
pF1KSD AAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKTD
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KSD PLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGGLGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGGLGPK
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090
pF1KSD KLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLW
::::::::::::::::::::::::::::::::::::::::
XP_016 KLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLWYVRDPTTGKEGWVPASSLSV
1090 1100 1110 1120 1130 1140
XP_016 RLGPSGSAQCLSSSESSPGSAVLSNSSSCSEGGQAPFSDLQG
1150 1160 1170 1180
>>NP_079255 (OMIM: 609499) guanine nucleotide exchange f (1123 aa)
initn: 6872 init1: 6872 opt: 6881 Z-score: 5340.7 bits: 1000.0 E(85289): 0
Smith-Waterman score: 6881; 98.6% identity (99.1% similar) in 1057 aa overlap (40-1096:5-1061)
10 20 30 40 50 60
pF1KSD SPASHGPTHGPSDPRTCLPGRGAGGMRPHGRGALGCCGLCSFYTCHGAAGDEIMHQDIVP
: .: : : ... :..::::::::::
NP_079 MTVRRLSLLCRDLWALWLLLKAGADEIMHQDIVP
10 20 30
70 80 90 100 110 120
pF1KSD LCAADIQDQLKKRFAYLSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LCAADIQDQLKKRFAYLSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KSD AGIGFILVIDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AGIGFILVIDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRD
100 110 120 130 140 150
190 200 210 220 230 240
pF1KSD DFKMKVPVIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DFKMKVPVIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KSD MLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAKEDLRLALKEGHSVLESLRELQAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAKEDLRLALKEGHSVLESLRELQAEG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KSD SEPSVNQDQLDNQATVQRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SEPSVNQDQLDNQATVQRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAI
280 290 300 310 320 330
370 380 390 400 410 420
pF1KSD LDAASQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIGNKHYAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LDAASQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIGNKHYAV
340 350 360 370 380 390
430 440 450 460 470 480
pF1KSD DSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLASQPVDKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLASQPVDKC
400 410 420 430 440 450
490 500 510 520 530 540
pF1KSD QSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQDLMEHVRKVFQKQASMEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQDLMEHVRKVFQKQASMEEV
460 470 480 490 500 510
550 560 570 580 590 600
pF1KSD FHRRQASLKKLAARQTRPVQPVAPRPEALAKSPCPSPGIRRGSENSSSEGGALRRGPYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 FHRRQASLKKLAARQTRPVQPVAPRPEALAKSPCPSPGIRRGSENSSSEGGALRRGPYRR
520 530 540 550 560 570
610 620 630 640 650 660
pF1KSD AKSEMSESRQGRGSAGEEEESLAILRRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AKSEMSESRQGRGSAGEEEESLAILRRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLM
580 590 600 610 620 630
670 680 690 700 710 720
pF1KSD AHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLERMEDFQIYEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLERMEDFQIYEK
640 650 660 670 680 690
730 740 750 760 770 780
pF1KSD YCQNKPRSESLWRQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 YCQNKPRSESLWRQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSR
700 710 720 730 740 750
790 800 810 820 830 840
pF1KSD NCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 NCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGH
760 770 780 790 800 810
850 860 870 880 890 900
pF1KSD TKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 TKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVK
820 830 840 850 860 870
910 920 930 940 950 960
pF1KSD GDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACREASQHRALEQSQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 GDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACREASQHRALEQSQSL
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KSD PLPAPTSTSPSRGNSRNIKKLEERKTDPLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 PLPAPTSTSPSRGNSRNIKKLEERKTDPLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAP
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KSD EDDGGWSSAEEQINSSDAEEDGGLGPKKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EDDGGWSSAEEQINSSDAEEDGGLGPKKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQ
1000 1010 1020 1030 1040 1050
1090
pF1KSD EGDEGLW
:::::::
NP_079 EGDEGLWYVRDPTTGKEGWVPASSLSVRLGPSGSAQCLSSSESSPGSAVLSNSSSCSEGG
1060 1070 1080 1090 1100 1110
>>NP_001307745 (OMIM: 609499) guanine nucleotide exchang (1129 aa)
initn: 6867 init1: 6867 opt: 6870 Z-score: 5332.1 bits: 998.4 E(85289): 0
Smith-Waterman score: 6870; 99.5% identity (99.6% similar) in 1045 aa overlap (56-1096:23-1067)
30 40 50 60 70 80
pF1KSD CLPGRGAGGMRPHGRGALGCCGLCSFYTCHGAAG----DEIMHQDIVPLCAADIQDQLKK
:.:: ::::::::::::::::::::::
NP_001 MAEKGASRGTLRRLWSLPRRRRGTAGRSRPDEIMHQDIVPLCAADIQDQLKK
10 20 30 40 50
90 100 110 120 130 140
pF1KSD RFAYLSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFAYLSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRR
60 70 80 90 100 110
150 160 170 180 190 200
pF1KSD RDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLS
120 130 140 150 160 170
210 220 230 240 250 260
pF1KSD SVPDLHGYIDKSQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVPDLHGYIDKSQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAET
180 190 200 210 220 230
270 280 290 300 310 320
pF1KSD ELPNDVQSTSSVLCAHTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELPNDVQSTSSVLCAHTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDN
240 250 260 270 280 290
330 340 350 360 370 380
pF1KSD QATVQRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QATVQRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFT
300 310 320 330 340 350
390 400 410 420 430 440
pF1KSD DIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRH
360 370 380 390 400 410
450 460 470 480 490 500
pF1KSD LCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQE
420 430 440 450 460 470
510 520 530 540 550 560
pF1KSD IEKFLETGAENKIQELNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEKFLETGAENKIQELNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLA
480 490 500 510 520 530
570 580 590 600 610 620
pF1KSD ARQTRPVQPVAPRPEALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARQTRPVQPVAPRPEALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGR
540 550 560 570 580 590
630 640 650 660 670 680
pF1KSD GSAGEEEESLAILRRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSAGEEEESLAILRRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKK
600 610 620 630 640 650
690 700 710 720 730 740
pF1KSD DVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLW
660 670 680 690 700 710
750 760 770 780 790 800
pF1KSD RQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEAL
720 730 740 750 760 770
810 820 830 840 850 860
pF1KSD SSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPM
780 790 800 810 820 830
870 880 890 900 910 920
pF1KSD QRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNA
840 850 860 870 880 890
930 940 950 960 970 980
pF1KSD REEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSR
900 910 920 930 940 950
990 1000 1010 1020 1030 1040
pF1KSD GNSRNIKKLEERKTDPLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAPEDDGGWSSAEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNSRNIKKLEERKTDPLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAPEDDGGWSSAEEQ
960 970 980 990 1000 1010
1050 1060 1070 1080 1090
pF1KSD INSSDAEEDGGLGPKKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLW
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INSSDAEEDGGLGPKKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLWYVRDP
1020 1030 1040 1050 1060 1070
NP_001 TTGKEGWVPASSLSVRLGPSGSAQCLSSSESSPGSAVLSNSSSCSEGGQAPFSDLQG
1080 1090 1100 1110 1120
>>NP_001106203 (OMIM: 609499) guanine nucleotide exchang (1125 aa)
initn: 6867 init1: 6867 opt: 6867 Z-score: 5329.8 bits: 998.0 E(85289): 0
Smith-Waterman score: 6867; 100.0% identity (100.0% similar) in 1037 aa overlap (60-1096:27-1063)
30 40 50 60 70 80
pF1KSD RGAGGMRPHGRGALGCCGLCSFYTCHGAAGDEIMHQDIVPLCAADIQDQLKKRFAYLSGG
::::::::::::::::::::::::::::::
NP_001 MRFWLRTEEMALEEMVQRLNAVSKHTDEIMHQDIVPLCAADIQDQLKKRFAYLSGG
10 20 30 40 50
90 100 110 120 130 140
pF1KSD RGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVK
60 70 80 90 100 110
150 160 170 180 190 200
pF1KSD ASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGY
120 130 140 150 160 170
210 220 230 240 250 260
pF1KSD IDKSQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDKSQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQS
180 190 200 210 220 230
270 280 290 300 310 320
pF1KSD TSSVLCAHTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSSVLCAHTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLL
240 250 260 270 280 290
330 340 350 360 370 380
pF1KSD AQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAH
300 310 320 330 340 350
390 400 410 420 430 440
pF1KSD VEHLLRDLASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEHLLRDLASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAE
360 370 380 390 400 410
450 460 470 480 490 500
pF1KSD IARRRGLLSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IARRRGLLSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETG
420 430 440 450 460 470
510 520 530 540 550 560
pF1KSD AENKIQELNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AENKIQELNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQ
480 490 500 510 520 530
570 580 590 600 610 620
pF1KSD PVAPRPEALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVAPRPEALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEE
540 550 560 570 580 590
630 640 650 660 670 680
pF1KSD SLAILRRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLAILRRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNME
600 610 620 630 640 650
690 700 710 720 730 740
pF1KSD EIYHFHNRIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIYHFHNRIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPF
660 670 680 690 700 710
750 760 770 780 790 800
pF1KSD FQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILK
720 730 740 750 760 770
810 820 830 840 850 860
pF1KSD AVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHE
780 790 800 810 820 830
870 880 890 900 910 920
pF1KSD KAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQ
840 850 860 870 880 890
930 940 950 960 970 980
pF1KSD APTPEIKAAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APTPEIKAAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKK
900 910 920 930 940 950
990 1000 1010 1020 1030 1040
pF1KSD LEERKTDPLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEERKTDPLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEE
960 970 980 990 1000 1010
1050 1060 1070 1080 1090
pF1KSD DGGLGPKKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLW
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGGLGPKKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLWYVRDPTTGKEGWV
1020 1030 1040 1050 1060 1070
NP_001 PASSLSVRLGPSGSAQCLSSSESSPGSAVLSNSSSCSEGGQAPFSDLQG
1080 1090 1100 1110 1120
>>XP_016875986 (OMIM: 609499) PREDICTED: guanine nucleot (1096 aa)
initn: 6848 init1: 6848 opt: 6848 Z-score: 5315.2 bits: 995.3 E(85289): 0
Smith-Waterman score: 6848; 100.0% identity (100.0% similar) in 1034 aa overlap (63-1096:1-1034)
40 50 60 70 80 90
pF1KSD GGMRPHGRGALGCCGLCSFYTCHGAAGDEIMHQDIVPLCAADIQDQLKKRFAYLSGGRGQ
::::::::::::::::::::::::::::::
XP_016 MHQDIVPLCAADIQDQLKKRFAYLSGGRGQ
10 20 30
100 110 120 130 140 150
pF1KSD DGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASV
40 50 60 70 80 90
160 170 180 190 200 210
pF1KSD LRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDK
100 110 120 130 140 150
220 230 240 250 260 270
pF1KSD SQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSS
160 170 180 190 200 210
280 290 300 310 320 330
pF1KSD VLCAHTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLCAHTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQL
220 230 240 250 260 270
340 350 360 370 380 390
pF1KSD NETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEH
280 290 300 310 320 330
400 410 420 430 440 450
pF1KSD LLRDLASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRDLASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIAR
340 350 360 370 380 390
460 470 480 490 500 510
pF1KSD RRGLLSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRGLLSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAEN
400 410 420 430 440 450
520 530 540 550 560 570
pF1KSD KIQELNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIQELNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVA
460 470 480 490 500 510
580 590 600 610 620 630
pF1KSD PRPEALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRPEALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLA
520 530 540 550 560 570
640 650 660 670 680 690
pF1KSD ILRRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILRRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY
580 590 600 610 620 630
700 710 720 730 740 750
pF1KSD HFHNRIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFHNRIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQE
640 650 660 670 680 690
760 770 780 790 800 810
pF1KSD CQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVN
700 710 720 730 740 750
820 830 840 850 860 870
pF1KSD DSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAV
760 770 780 790 800 810
880 890 900 910 920 930
pF1KSD LFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPT
820 830 840 850 860 870
940 950 960 970 980 990
pF1KSD PEIKAAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEIKAAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEE
880 890 900 910 920 930
1000 1010 1020 1030 1040 1050
pF1KSD RKTDPLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKTDPLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGG
940 950 960 970 980 990
1060 1070 1080 1090
pF1KSD LGPKKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLW
::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGPKKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLWYVRDPTTGKEGWVPAS
1000 1010 1020 1030 1040 1050
XP_016 SLSVRLGPSGSAQCLSSSESSPGSAVLSNSSSCSEGGQAPFSDLQG
1060 1070 1080 1090
>>XP_016875982 (OMIM: 609499) PREDICTED: guanine nucleot (1207 aa)
initn: 6787 init1: 6787 opt: 6796 Z-score: 5274.3 bits: 987.8 E(85289): 0
Smith-Waterman score: 7270; 97.8% identity (97.8% similar) in 1121 aa overlap (1-1096:25-1145)
10 20 30
pF1KSD MPLRGGAGPSPASHGPTHGPSDPRTCLPGRGAGGMR
::::::::::::::::::::::::::::::::::::
XP_016 MARVESPVPAARASLTGSCVLGQAMPLRGGAGPSPASHGPTHGPSDPRTCLPGRGAGGMR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD PHGRGALGCCGLCSFYTCHGAAGDEIMHQDIVPLCAADIQDQLKKRFAYLSGGRGQDGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHGRGALGCCGLCSFYTCHGAAGDEIMHQDIVPLCAADIQDQLKKRFAYLSGGRGQDGSP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD VITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASVLRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASVLRIA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD ASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQLT
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD EDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD HTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQLNETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQLNETE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD AAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEHLLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEHLLRD
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD LASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIARRRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIARRRGL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD LSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQE
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD LNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD ALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILRR
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD HVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHN
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD RIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRK
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD LDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMH
790 800 810 820 830 840
820 830 840 850 860 870
pF1KSD LIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCK
850 860 870 880 890 900
880 890 900 910 920 930
pF1KSD KREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIK
910 920 930 940 950 960
940 950 960 970 980 990
pF1KSD AAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKTD
970 980 990 1000 1010 1020
1000 1010 1020 1030
pF1KSD PLSLEGYVSSAPLTKPPEKGK-------------------------GWSKTSHSLEAPED
::::::::::::::::::::: ::::::::::::::
XP_016 PLSLEGYVSSAPLTKPPEKGKASPTSPDKKAKRHEVKSDPTPFGVRGWSKTSHSLEAPED
1030 1040 1050 1060 1070 1080
1040 1050 1060 1070 1080 1090
pF1KSD DGGWSSAEEQINSSDAEEDGGLGPKKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGGWSSAEEQINSSDAEEDGGLGPKKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEG
1090 1100 1110 1120 1130 1140
pF1KSD DEGLW
:::::
XP_016 DEGLWYVRDPTTGKEGWVPASSLSVRLGPSGSAQCLSSSESSPGSAVLSNSSSCSEGGQA
1150 1160 1170 1180 1190 1200
>>XP_011535788 (OMIM: 609499) PREDICTED: guanine nucleot (1238 aa)
initn: 6794 init1: 6794 opt: 6794 Z-score: 5272.6 bits: 987.6 E(85289): 0
Smith-Waterman score: 7043; 95.0% identity (95.0% similar) in 1128 aa overlap (1-1072:25-1152)
10 20 30
pF1KSD MPLRGGAGPSPASHGPTHGPSDPRTCLPGRGAGGMR
::::::::::::::::::::::::::::::::::::
XP_011 MARVESPVPAARASLTGSCVLGQAMPLRGGAGPSPASHGPTHGPSDPRTCLPGRGAGGMR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD PHGRGALGCCGLCSFYTCHGAAGDEIMHQDIVPLCAADIQDQLKKRFAYLSGGRGQDGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHGRGALGCCGLCSFYTCHGAAGDEIMHQDIVPLCAADIQDQLKKRFAYLSGGRGQDGSP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD VITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASVLRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASVLRIA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD ASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQLT
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD EDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD HTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQLNETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQLNETE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD AAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEHLLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEHLLRD
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD LASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIARRRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIARRRGL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD LSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQE
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD LNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD ALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILRR
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD HVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHN
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD RIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRK
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD LDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMH
790 800 810 820 830 840
820 830 840 850 860 870
pF1KSD LIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCK
850 860 870 880 890 900
880 890 900 910 920 930
pF1KSD KREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIK
910 920 930 940 950 960
940 950 960 970 980 990
pF1KSD AAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKTD
970 980 990 1000 1010 1020
1000 1010
pF1KSD PLSLEGYVSSAPLTKPPEKGK---------------------------------------
:::::::::::::::::::::
XP_011 PLSLEGYVSSAPLTKPPEKGKDDTVTSSASESSALSRKRFTLQGFANLKGQKASPTSPDK
1030 1040 1050 1060 1070 1080
1020 1030 1040 1050 1060
pF1KSD -----------------GWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGGLGPKKLVP
:::::::::::::::::::::::::::::::::::::::::::
XP_011 KAKRHEVKSDPTPFGVRGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGGLGPKKLVP
1090 1100 1110 1120 1130 1140
1070 1080 1090
pF1KSD GKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLW
::::::::::::
XP_011 GKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLWYVRDPTTGKEGWVPASSLSVRLGP
1150 1160 1170 1180 1190 1200
>>XP_016875988 (OMIM: 609499) PREDICTED: guanine nucleot (1043 aa)
initn: 6787 init1: 6787 opt: 6787 Z-score: 5268.2 bits: 986.5 E(85289): 0
Smith-Waterman score: 6787; 100.0% identity (100.0% similar) in 1017 aa overlap (1-1017:25-1041)
10 20 30
pF1KSD MPLRGGAGPSPASHGPTHGPSDPRTCLPGRGAGGMR
::::::::::::::::::::::::::::::::::::
XP_016 MARVESPVPAARASLTGSCVLGQAMPLRGGAGPSPASHGPTHGPSDPRTCLPGRGAGGMR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD PHGRGALGCCGLCSFYTCHGAAGDEIMHQDIVPLCAADIQDQLKKRFAYLSGGRGQDGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHGRGALGCCGLCSFYTCHGAAGDEIMHQDIVPLCAADIQDQLKKRFAYLSGGRGQDGSP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD VITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASVLRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASVLRIA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD ASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQLT
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD EDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD HTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQLNETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQLNETE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD AAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEHLLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEHLLRD
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD LASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIARRRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIARRRGL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD LSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQE
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD LNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD ALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILRR
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD HVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHN
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD RIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRK
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD LDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMH
790 800 810 820 830 840
820 830 840 850 860 870
pF1KSD LIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCK
850 860 870 880 890 900
880 890 900 910 920 930
pF1KSD KREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIK
910 920 930 940 950 960
940 950 960 970 980 990
pF1KSD AAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKTD
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KSD PLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGGLGPK
:::::::::::::::::::::
XP_016 PLSLEGYVSSAPLTKPPEKGKEP
1030 1040
>>XP_016875987 (OMIM: 609499) PREDICTED: guanine nucleot (1087 aa)
initn: 6409 init1: 6409 opt: 6409 Z-score: 4975.0 bits: 932.3 E(85289): 0
Smith-Waterman score: 6409; 100.0% identity (100.0% similar) in 970 aa overlap (127-1096:56-1025)
100 110 120 130 140 150
pF1KSD VITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASVLRIA
::::::::::::::::::::::::::::::
XP_016 IFSQHRSHATTSESLTWTSTGTSDARTGVILQDAGIGFILVIDRRRDKWTSVKASVLRIA
30 40 50 60 70 80
160 170 180 190 200 210
pF1KSD ASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQLT
90 100 110 120 130 140
220 230 240 250 260 270
pF1KSD EDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCA
150 160 170 180 190 200
280 290 300 310 320 330
pF1KSD HTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQLNETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQLNETE
210 220 230 240 250 260
340 350 360 370 380 390
pF1KSD AAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEHLLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEHLLRD
270 280 290 300 310 320
400 410 420 430 440 450
pF1KSD LASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIARRRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIARRRGL
330 340 350 360 370 380
460 470 480 490 500 510
pF1KSD LSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQE
390 400 410 420 430 440
520 530 540 550 560 570
pF1KSD LNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE
450 460 470 480 490 500
580 590 600 610 620 630
pF1KSD ALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILRR
510 520 530 540 550 560
640 650 660 670 680 690
pF1KSD HVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHN
570 580 590 600 610 620
700 710 720 730 740 750
pF1KSD RIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRK
630 640 650 660 670 680
760 770 780 790 800 810
pF1KSD LDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSMH
690 700 710 720 730 740
820 830 840 850 860 870
pF1KSD LIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCK
750 760 770 780 790 800
880 890 900 910 920 930
pF1KSD KREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIK
810 820 830 840 850 860
940 950 960 970 980 990
pF1KSD AAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKTD
870 880 890 900 910 920
1000 1010 1020 1030 1040 1050
pF1KSD PLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGGLGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGGLGPK
930 940 950 960 970 980
1060 1070 1080 1090
pF1KSD KLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLW
::::::::::::::::::::::::::::::::::::::::
XP_016 KLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLWYVRDPTTGKEGWVPASSLSV
990 1000 1010 1020 1030 1040
XP_016 RLGPSGSAQCLSSSESSPGSAVLSNSSSCSEGGQAPFSDLQG
1050 1060 1070 1080
>>NP_001307744 (OMIM: 609499) guanine nucleotide exchang (1148 aa)
initn: 6329 init1: 6329 opt: 6347 Z-score: 4926.6 bits: 923.4 E(85289): 0
Smith-Waterman score: 6821; 96.3% identity (96.9% similar) in 1082 aa overlap (40-1096:5-1086)
10 20 30 40 50 60
pF1KSD SPASHGPTHGPSDPRTCLPGRGAGGMRPHGRGALGCCGLCSFYTCHGAAGDEIMHQDIVP
: .: : : ... :..::::::::::
NP_001 MTVRRLSLLCRDLWALWLLLKAGADEIMHQDIVP
10 20 30
70 80 90 100 110 120
pF1KSD LCAADIQDQLKKRFAYLSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCAADIQDQLKKRFAYLSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KSD AGIGFILVIDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGIGFILVIDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRD
100 110 120 130 140 150
190 200 210 220 230 240
pF1KSD DFKMKVPVIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFKMKVPVIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KSD MLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAKEDLRLALKEGHSVLESLRELQAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAKEDLRLALKEGHSVLESLRELQAEG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KSD SEPSVNQDQLDNQATVQRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEPSVNQDQLDNQATVQRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAI
280 290 300 310 320 330
370 380 390 400 410 420
pF1KSD LDAASQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIGNKHYAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDAASQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIGNKHYAV
340 350 360 370 380 390
430 440 450 460 470 480
pF1KSD DSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLASQPVDKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLASQPVDKC
400 410 420 430 440 450
490 500 510 520 530 540
pF1KSD QSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQDLMEHVRKVFQKQASMEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQDLMEHVRKVFQKQASMEEV
460 470 480 490 500 510
550 560 570 580 590 600
pF1KSD FHRRQASLKKLAARQTRPVQPVAPRPEALAKSPCPSPGIRRGSENSSSEGGALRRGPYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHRRQASLKKLAARQTRPVQPVAPRPEALAKSPCPSPGIRRGSENSSSEGGALRRGPYRR
520 530 540 550 560 570
610 620 630 640 650 660
pF1KSD AKSEMSESRQGRGSAGEEEESLAILRRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKSEMSESRQGRGSAGEEEESLAILRRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLM
580 590 600 610 620 630
670 680 690 700 710 720
pF1KSD AHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLERMEDFQIYEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLERMEDFQIYEK
640 650 660 670 680 690
730 740 750 760 770 780
pF1KSD YCQNKPRSESLWRQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YCQNKPRSESLWRQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSR
700 710 720 730 740 750
790 800 810 820 830 840
pF1KSD NCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGH
760 770 780 790 800 810
850 860 870 880 890 900
pF1KSD TKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVK
820 830 840 850 860 870
910 920 930 940 950 960
pF1KSD GDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACREASQHRALEQSQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACREASQHRALEQSQSL
880 890 900 910 920 930
970 980 990 1000 1010
pF1KSD PLPAPTSTSPSRGNSRNIKKLEERKTDPLSLEGYVSSAPLTKPPEKGK------------
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLPAPTSTSPSRGNSRNIKKLEERKTDPLSLEGYVSSAPLTKPPEKGKASPTSPDKKAKR
940 950 960 970 980 990
1020 1030 1040 1050 1060
pF1KSD -------------GWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGGLGPKKLVPGKYT
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEVKSDPTPFGVRGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGGLGPKKLVPGKYT
1000 1010 1020 1030 1040 1050
1070 1080 1090
pF1KSD VVADHEKGGPDALRVRSGDVVELVQEGDEGLW
::::::::::::::::::::::::::::::::
NP_001 VVADHEKGGPDALRVRSGDVVELVQEGDEGLWYVRDPTTGKEGWVPASSLSVRLGPSGSA
1060 1070 1080 1090 1100 1110
NP_001 QCLSSSESSPGSAVLSNSSSCSEGGQAPFSDLQG
1120 1130 1140
1096 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 01:25:19 2016 done: Thu Nov 3 01:25:21 2016
Total Scan time: 14.610 Total Display time: 0.590
Function used was FASTA [36.3.4 Apr, 2011]