Result of FASTA (omim) for
pFN21AB3038
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3038, 1401 aa
1>>>pF1KB3038 1401 - 1401 aa - 1401 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.8711+/-0.000415; mu= -3.5020+/- 0.026
mean_var=252.5029+/-52.357, 0's: 0 Z-trim(118.9): 123 B-trim: 0 in 0/56
Lambda= 0.080713
statistics sampled from 32176 (32303) to 32176 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.379), width: 16
Scan time: 14.100
The best scores are: opt bits E(85289)
NP_066963 (OMIM: 147920,300128,300867) lysine-spec (1401) 9483 1118.6 0
NP_001278345 (OMIM: 147920,300128,300867) lysine-s (1408) 9167 1081.8 0
XP_011542266 (OMIM: 147920,300128,300867) PREDICTE (1437) 8764 1034.9 0
XP_011542276 (OMIM: 147920,300128,300867) PREDICTE (1293) 8752 1033.5 0
XP_011542269 (OMIM: 147920,300128,300867) PREDICTE (1420) 8669 1023.8 0
XP_011542265 (OMIM: 147920,300128,300867) PREDICTE (1444) 8448 998.1 0
XP_016885271 (OMIM: 147920,300128,300867) PREDICTE (1427) 8347 986.3 0
XP_011529751 (OMIM: 400009) PREDICTED: histone dem (1530) 8143 962.6 0
NP_001245181 (OMIM: 400009) histone demethylase UT (1392) 8136 961.8 0
XP_016885556 (OMIM: 400009) PREDICTED: histone dem (1387) 8121 960.0 0
XP_011542264 (OMIM: 147920,300128,300867) PREDICTE (1456) 7950 940.1 0
XP_011529749 (OMIM: 400009) PREDICTED: histone dem (1537) 7843 927.7 0
NP_001245187 (OMIM: 400009) histone demethylase UT (1399) 7836 926.8 0
NP_001245185 (OMIM: 400009) histone demethylase UT (1335) 7789 921.3 0
XP_011542263 (OMIM: 147920,300128,300867) PREDICTE (1463) 7628 902.6 0
NP_001245190 (OMIM: 400009) histone demethylase UT (1389) 7061 836.6 0
XP_011529750 (OMIM: 400009) PREDICTED: histone dem (1531) 6941 822.6 0
XP_011542273 (OMIM: 147920,300128,300867) PREDICTE (1393) 6904 818.3 0
XP_016885273 (OMIM: 147920,300128,300867) PREDICTE (1193) 6794 805.5 0
XP_005262575 (OMIM: 400009) PREDICTED: histone dem (1182) 6762 801.7 0
NP_001278346 (OMIM: 147920,300128,300867) lysine-s (1356) 6582 780.8 0
XP_011542275 (OMIM: 147920,300128,300867) PREDICTE (1375) 6563 778.6 0
NP_001278350 (OMIM: 147920,300128,300867) lysine-s (1105) 6545 776.5 0
NP_001278344 (OMIM: 147920,300128,300867) lysine-s (1453) 6543 776.3 0
XP_011542262 (OMIM: 147920,300128,300867) PREDICTE (1472) 6543 776.3 0
NP_001245193 (OMIM: 400009) histone demethylase UT (1376) 6275 745.1 8.6e-214
XP_005272716 (OMIM: 147920,300128,300867) PREDICTE (1367) 6269 744.4 1.4e-213
XP_011542267 (OMIM: 147920,300128,300867) PREDICTE (1429) 6185 734.6 1.3e-210
XP_016885272 (OMIM: 147920,300128,300867) PREDICTE (1374) 6165 732.2 6.1e-210
XP_016885274 (OMIM: 147920,300128,300867) PREDICTE (1071) 6089 723.4 2.3e-207
NP_001278347 (OMIM: 147920,300128,300867) lysine-s (1322) 6089 723.4 2.7e-207
XP_005272713 (OMIM: 147920,300128,300867) PREDICTE (1419) 6089 723.4 2.9e-207
NP_001245195 (OMIM: 400009) histone demethylase UT (1367) 5982 710.9 1.6e-203
XP_011529766 (OMIM: 400009) PREDICTED: histone dem (1124) 5865 697.3 1.7e-199
XP_011542274 (OMIM: 147920,300128,300867) PREDICTE (1392) 5863 697.1 2.4e-199
XP_011542270 (OMIM: 147920,300128,300867) PREDICTE (1411) 5844 694.9 1.1e-198
XP_011542277 (OMIM: 147920,300128,300867) PREDICTE (1238) 5824 692.5 5e-198
XP_011542260 (OMIM: 147920,300128,300867) PREDICTE (1489) 5824 692.6 5.9e-198
XP_011542259 (OMIM: 147920,300128,300867) PREDICTE (1508) 5824 692.6 6e-198
XP_011542272 (OMIM: 147920,300128,300867) PREDICTE (1403) 5550 660.6 2.3e-188
XP_011542268 (OMIM: 147920,300128,300867) PREDICTE (1422) 5528 658.1 1.3e-187
XP_011542271 (OMIM: 147920,300128,300867) PREDICTE (1410) 5446 648.5 1e-184
XP_011529754 (OMIM: 400009) PREDICTED: histone dem (1485) 5399 643.1 4.7e-183
XP_011529752 (OMIM: 400009) PREDICTED: histone dem (1515) 5399 643.1 4.7e-183
NP_001245188 (OMIM: 400009) histone demethylase UT (1331) 5394 642.5 6.3e-183
XP_011529744 (OMIM: 400009) PREDICTED: histone dem (1582) 5395 642.6 6.8e-183
NP_001245194 (OMIM: 400009) histone demethylase UT (1264) 5392 642.2 7.1e-183
NP_009056 (OMIM: 400009) histone demethylase UTY i (1347) 5392 642.2 7.5e-183
NP_001245189 (OMIM: 400009) histone demethylase UT (1377) 5392 642.2 7.7e-183
XP_011529760 (OMIM: 400009) PREDICTED: histone dem (1422) 5388 641.8 1.1e-182
>>NP_066963 (OMIM: 147920,300128,300867) lysine-specific (1401 aa)
initn: 9483 init1: 9483 opt: 9483 Z-score: 5978.0 bits: 1118.6 E(85289): 0
Smith-Waterman score: 9483; 100.0% identity (100.0% similar) in 1401 aa overlap (1-1401:1-1401)
10 20 30 40 50 60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB3 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB3 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB3 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB3 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM
1330 1340 1350 1360 1370 1380
1390 1400
pF1KB3 EDLMQVYDQFTLAPPLPSASS
:::::::::::::::::::::
NP_066 EDLMQVYDQFTLAPPLPSASS
1390 1400
>>NP_001278345 (OMIM: 147920,300128,300867) lysine-speci (1408 aa)
initn: 9181 init1: 6537 opt: 9167 Z-score: 5779.1 bits: 1081.8 E(85289): 0
Smith-Waterman score: 9175; 96.9% identity (97.8% similar) in 1410 aa overlap (1-1401:1-1408)
10 20 30 40 50 60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
::::::::::::::::::::::::::::::::::::::: :. . . . : .
NP_001 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQA--CKPHHPNTEPVLGLSQTPI
370 380 390 400 410
430 440 450 460 470
pF1KB3 EAWSLP---IPA----ELTS--RQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTP
::: ::. .:.: .. .. .::::::::::::::::::::::::::::
NP_001 SQQSLPLHMIPSSQVDDLSSPAKRKRTSSPTKNTSDNWSGGHAVSHPPVQQQAHSWCLTP
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB3 QKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADS
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB3 SLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTI
540 550 560 570 580 590
600 610 620 630 640 650
pF1KB3 LIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHS
600 610 620 630 640 650
660 670 680 690 700 710
pF1KB3 AGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQG
660 670 680 690 700 710
720 730 740 750 760 770
pF1KB3 ITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPG
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB3 LLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPK
780 790 800 810 820 830
840 850 860 870 880 890
pF1KB3 STEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYP
840 850 860 870 880 890
900 910 920 930 940 950
pF1KB3 SSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDA
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KB3 FFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADEN
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KB3 WDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNS
1020 1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
pF1KB3 GRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNT
1080 1090 1100 1110 1120 1130
1140 1150 1160 1170 1180 1190
pF1KB3 VQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMG
1140 1150 1160 1170 1180 1190
1200 1210 1220 1230 1240 1250
pF1KB3 SWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKL
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
pF1KB3 AVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALI
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360 1370
pF1KB3 AAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLEN
1320 1330 1340 1350 1360 1370
1380 1390 1400
pF1KB3 FVVLEQYKMEDLMQVYDQFTLAPPLPSASS
::::::::::::::::::::::::::::::
NP_001 FVVLEQYKMEDLMQVYDQFTLAPPLPSASS
1380 1390 1400
>>XP_011542266 (OMIM: 147920,300128,300867) PREDICTED: l (1437 aa)
initn: 8752 init1: 8752 opt: 8764 Z-score: 5525.3 bits: 1034.9 E(85289): 0
Smith-Waterman score: 9381; 97.5% identity (97.5% similar) in 1433 aa overlap (1-1397:1-1433)
10 20 30 40 50 60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB3 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB3 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
1210 1220 1230 1240 1250 1260
1270 1280 1290
pF1KB3 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIK---------------------------
:::::::::::::::::::::::::::::::::
XP_011 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKIFSLSPNFRAEKCLRDHLVQPLRSNGE
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340
pF1KB3 ---------YCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFV
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEPLRFTGEYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFV
1330 1340 1350 1360 1370 1380
1350 1360 1370 1380 1390 1400
pF1KB3 TNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
1390 1400 1410 1420 1430
>>XP_011542276 (OMIM: 147920,300128,300867) PREDICTED: l (1293 aa)
initn: 8752 init1: 8752 opt: 8752 Z-score: 5518.5 bits: 1033.5 E(85289): 0
Smith-Waterman score: 8752; 100.0% identity (100.0% similar) in 1293 aa overlap (1-1293:1-1293)
10 20 30 40 50 60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB3 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB3 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB3 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
:::::::::::::::::::::::::::::::::
XP_011 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIK
1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KB3 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM
>>XP_011542269 (OMIM: 147920,300128,300867) PREDICTED: l (1420 aa)
initn: 8656 init1: 8656 opt: 8669 Z-score: 5465.6 bits: 1023.8 E(85289): 0
Smith-Waterman score: 9435; 98.7% identity (98.7% similar) in 1420 aa overlap (1-1401:1-1420)
10 20 30 40 50 60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
70 80 90 100 110 120
130 140 150 160
pF1KB3 SLQSDYWK-------------------NAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDP
:::::::: :::::::::::::::::::::::::::::::::
XP_011 SLQSDYWKMRNPWIQRAHCIPLDQYTTNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB3 SFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKY
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB3 HSAKEAYEQLLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSAKEAYEQLLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADP
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB3 NSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAY
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB3 ICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB3 CNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQ
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB3 QQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRST
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB3 GIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCST
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB3 SRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQ
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB3 GLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB3 HTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCS
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB3 PSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSS
790 800 810 820 830 840
830 840 850 860 870 880
pF1KB3 AISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQI
850 860 870 880 890 900
890 900 910 920 930 940
pF1KB3 IPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTP
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KB3 SIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVR
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KB3 TQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHS
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KB3 DSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSH
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KB3 VGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFC
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KB3 EKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNV
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KB3 GPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLK
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KB3 QCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDC
1330 1340 1350 1360 1370 1380
1370 1380 1390 1400
pF1KB3 ARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
::::::::::::::::::::::::::::::::::::::::
XP_011 ARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
1390 1400 1410 1420
>>XP_011542265 (OMIM: 147920,300128,300867) PREDICTED: l (1444 aa)
initn: 8450 init1: 5806 opt: 8448 Z-score: 5326.4 bits: 998.1 E(85289): 0
Smith-Waterman score: 9073; 94.5% identity (95.4% similar) in 1442 aa overlap (1-1397:1-1440)
10 20 30 40 50 60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
::::::::::::::::::::::::::::::::::::::: :. . . . : .
XP_011 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQA--CKPHHPNTEPVLGLSQTPI
370 380 390 400 410
430 440 450 460 470
pF1KB3 EAWSLP---IPA----ELTS--RQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTP
::: ::. .:.: .. .. .::::::::::::::::::::::::::::
XP_011 SQQSLPLHMIPSSQVDDLSSPAKRKRTSSPTKNTSDNWSGGHAVSHPPVQQQAHSWCLTP
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB3 QKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADS
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB3 SLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTI
540 550 560 570 580 590
600 610 620 630 640 650
pF1KB3 LIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHS
600 610 620 630 640 650
660 670 680 690 700 710
pF1KB3 AGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQG
660 670 680 690 700 710
720 730 740 750 760 770
pF1KB3 ITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPG
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB3 LLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPK
780 790 800 810 820 830
840 850 860 870 880 890
pF1KB3 STEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYP
840 850 860 870 880 890
900 910 920 930 940 950
pF1KB3 SSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDA
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KB3 FFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADEN
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KB3 WDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNS
1020 1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
pF1KB3 GRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNT
1080 1090 1100 1110 1120 1130
1140 1150 1160 1170 1180 1190
pF1KB3 VQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMG
1140 1150 1160 1170 1180 1190
1200 1210 1220 1230 1240 1250
pF1KB3 SWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKL
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290
pF1KB3 AVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIK------------------
::::::::::::::::::::::::::::::::::::::::::
XP_011 AVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKIFSLSPNFRAEKCLRDHL
1260 1270 1280 1290 1300 1310
1300 1310 1320 1330
pF1KB3 ------------------YCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICE
::::::::::::::::::::::::::::::::::::::::::
XP_011 VQPLRSNGEPEPLRFTGEYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICE
1320 1330 1340 1350 1360 1370
1340 1350 1360 1370 1380 1390
pF1KB3 VEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPP
1380 1390 1400 1410 1420 1430
1400
pF1KB3 LPSASS
::
XP_011 LPSASS
1440
>>XP_016885271 (OMIM: 147920,300128,300867) PREDICTED: l (1427 aa)
initn: 8354 init1: 6537 opt: 8347 Z-score: 5263.0 bits: 986.3 E(85289): 0
Smith-Waterman score: 9127; 95.6% identity (96.5% similar) in 1429 aa overlap (1-1401:1-1427)
10 20 30 40 50 60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
70 80 90 100 110 120
130 140 150 160
pF1KB3 SLQSDYWK-------------------NAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDP
:::::::: :::::::::::::::::::::::::::::::::
XP_016 SLQSDYWKMRNPWIQRAHCIPLDQYTTNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB3 SFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKY
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB3 HSAKEAYEQLLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSAKEAYEQLLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADP
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB3 NSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAY
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB3 ICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQA--
370 380 390 400 410
410 420 430 440 450
pF1KB3 CNLPQGSLQNKTKLLPSIEEAWSLP---IPA----ELTS--RQGAMNTAQQNTSDNWSGG
:. . . . : . ::: ::. .:.: .. .. .:::::::::
XP_016 CKPHHPNTEPVLGLSQTPISQQSLPLHMIPSSQVDDLSSPAKRKRTSSPTKNTSDNWSGG
420 430 440 450 460 470
460 470 480 490 500 510
pF1KB3 HAVSHPPVQQQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAVSHPPVQQQAHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRP
480 490 500 510 520 530
520 530 540 550 560 570
pF1KB3 TGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPF
540 550 560 570 580 590
580 590 600 610 620 630
pF1KB3 SAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPW
600 610 620 630 640 650
640 650 660 670 680 690
pF1KB3 KNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQ
660 670 680 690 700 710
700 710 720 730 740 750
pF1KB3 GAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVH
720 730 740 750 760 770
760 770 780 790 800 810
pF1KB3 QMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTD
780 790 800 810 820 830
820 830 840 850 860 870
pF1KB3 NSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLL
840 850 860 870 880 890
880 890 900 910 920 930
pF1KB3 VNHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLP
900 910 920 930 940 950
940 950 960 970 980 990
pF1KB3 KDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEA
960 970 980 990 1000 1010
1000 1010 1020 1030 1040 1050
pF1KB3 NNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENE
1020 1030 1040 1050 1060 1070
1060 1070 1080 1090 1100 1110
pF1KB3 KRSHHKDHSDSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRSHHKDHSDSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRV
1080 1090 1100 1110 1120 1130
1120 1130 1140 1150 1160 1170
pF1KB3 VSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEG
1140 1150 1160 1170 1180 1190
1180 1190 1200 1210 1220 1230
pF1KB3 YWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIG
1200 1210 1220 1230 1240 1250
1240 1250 1260 1270 1280 1290
pF1KB3 WCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMI
1260 1270 1280 1290 1300 1310
1300 1310 1320 1330 1340 1350
pF1KB3 KYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRK
1320 1330 1340 1350 1360 1370
1360 1370 1380 1390 1400
pF1KB3 TYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYIVHCQDCARKTSGNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSASS
1380 1390 1400 1410 1420
>>XP_011529751 (OMIM: 400009) PREDICTED: histone demethy (1530 aa)
initn: 7885 init1: 3953 opt: 8143 Z-score: 5134.1 bits: 962.6 E(85289): 0
Smith-Waterman score: 8143; 86.5% identity (94.3% similar) in 1397 aa overlap (1-1397:1-1389)
10 20 30 40 50 60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
::::.:::.::: .::::: :::: :::: :::: : :::.::::::::.::::::::
XP_011 MKSCAVSLTTAA---VAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
:.::::::::.:::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
:::.:::::::::::::::::.::::.:::::::.:::::::::::::::::::::::::
XP_011 SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
:::.::::::::::.:::::::::::::::::::::::::::::::::::::::::: ::
XP_011 TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
::::::::::::::..::.:::::::::::::::::::::::::::::::::::::::::
XP_011 VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
::::::::::::::::::.::: :::::.::::::.::::::::::.:::::::::::::
XP_011 LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQAQLCNLPQSSLQNKTKLLPSIE
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
:::::::::::::::::::::::: ::::.::...:: :::: ..: :::::::::::::
XP_011 EAWSLPIPAELTSRQGAMNTAQQNGSDNWNGGQSLSHHPVQQ-VYSLCLTPQKLQHLEQL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
::::.::::::: .::::::::::::: :: :::::.::: :: .::::::::::.
XP_011 RANRDNLNPAQKHQLEQLESQFVLMQQ--MRHKEVAQVRTTGIHNGAITDSSLPTNSVSN
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
.::. ::::: ::::::::::: . :..: :::: .::.::. ::::::::.:.: :.:
XP_011 RQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTILLGSNCIAG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
: :::::::::.:. :::::.:.:.::.::::..:::::.:::::.::: .::: :.::
XP_011 SESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPL
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
::: .:. ::...::.. : : ::::::: :: : .::: ::::::::::: .::::::
XP_011 FSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKP
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
: : :::::::::.: :. :.:.:: :::::. :::: ::.::: ::.:: .:::::
XP_011 SKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGD--SPNLLIADNPQL
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
::::.::::.::::::::::::::::::::::.:::::::::::::::::::::: . ::
XP_011 SALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINS
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
:::::::::::::.::::. .::: :.:: :..:. . ::.::::::: :::.::::::
XP_011 VTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKAC
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
:: :::::::: ::::::::::::.:::::::::::::::::::::::::::::::::::
XP_011 RNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB3 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
:.::::::::::::::::::::::::::::::::..::::::.:::::.:::::::::::
XP_011 WRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFK
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB3 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
::::::::::::.::::::::::::::::.:::::::::.::::::::::::::::::::
XP_011 TIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPG
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB3 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
::::::::::::::::::::::::::::::: ::::::::::::::::::.:::::::::
XP_011 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDL
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB3 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_011 YEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNK
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB3 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
:.:::: ::::::::::::::::::::::::::::::. ::: :::::::.:::::.:::
XP_011 LKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLREALVAAGKEVIWH
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB3 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM
:::..::::::::::::::.:::::::::..:::::::.::::::: .::::::::::::
XP_011 GRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCHDCARKTSKSLENFVVLEQYKM
1320 1330 1340 1350 1360 1370
1390 1400
pF1KB3 EDLMQVYDQFTLAPPLPSASS
:::.::::::::: : :
XP_011 EDLIQVYDQFTLASPWPPMDQSAFTSSLLRPIKALGSGRAEQTSGDQLQKGATHSRASSL
1380 1390 1400 1410 1420 1430
>>NP_001245181 (OMIM: 400009) histone demethylase UTY is (1392 aa)
initn: 6742 init1: 3937 opt: 8136 Z-score: 5130.3 bits: 961.8 E(85289): 0
Smith-Waterman score: 8136; 86.4% identity (94.3% similar) in 1400 aa overlap (1-1400:1-1392)
10 20 30 40 50 60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
::::.:::.::: .::::: :::: :::: :::: : :::.::::::::.::::::::
NP_001 MKSCAVSLTTAA---VAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
:.::::::::.:::::::::::::::::::::::::::::::::::::: ::::::::::
NP_001 RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
:::.:::::::::::::::::.::::.:::::::.:::::::::::::::::::::::::
NP_001 SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
:::.::::::::::.:::::::::::::::::::::::::::::::::::::::::: ::
NP_001 TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
::::::::::::::..::.:::::::::::::::::::::::::::::::::::::::::
NP_001 VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
::::::::::::::::::.::: :::::.::::::.::::::::::.:::::::::::::
NP_001 LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQAQLCNLPQSSLQNKTKLLPSIE
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
:::::::::::::::::::::::: ::::.::...:: :::: ..: :::::::::::::
NP_001 EAWSLPIPAELTSRQGAMNTAQQNGSDNWNGGQSLSHHPVQQ-VYSLCLTPQKLQHLEQL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
::::.::::::: .:::::::::::: ::: :::::.::: :: .::::::::::.
NP_001 RANRDNLNPAQKHQLEQLESQFVLMQ--QMRHKEVAQVRTTGIHNGAITDSSLPTNSVSN
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
.::. ::::: ::::::::::: . :..: :::: .::.::. ::::::::.:.: :.:
NP_001 RQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTILLGSNCIAG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
: :::::::::.:. :::::.:.:.::.::::..:::::.:::::.::: .::: :.::
NP_001 SESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPL
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
::: .:. ::...::.. : : ::::::: :: : .::: ::::::::::: .::::::
NP_001 FSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKP
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
: : :::::::::.: :. :.:.:: :::::. :::: ::.:::: :.:: .:::::
NP_001 SKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDS--PNLLIADNPQL
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
::::.::::.::::::::::::::::::::::.:::::::::::::::::::::: . ::
NP_001 SALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINS
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
:::::::::::::.::::. .::: :.:: :..:. . ::.::::::: :::.::::::
NP_001 VTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKAC
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
:: :::::::: ::::::::::::.:::::::::::::::::::::::::::::::::::
NP_001 RNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB3 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
:.::::::::::::::::::::::::::::::::..::::::.:::::.:::::::::::
NP_001 WRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFK
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB3 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
::::::::::::.::::::::::::::::.:::::::::.::::::::::::::::::::
NP_001 TIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPG
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB3 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
::::::::::::::::::::::::::::::: ::::::::::::::::::.:::::::::
NP_001 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDL
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB3 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
NP_001 YEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNK
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB3 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
:.:::: ::::::::::::::::::::::::::::::. ::: :::::::.:::::.:::
NP_001 LKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLREALVAAGKEVIWH
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB3 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM
:::..::::::::::::::.:::::::::..:::::::.::::::: .::::::::::::
NP_001 GRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCHDCARKTSKSLENFVVLEQYKM
1320 1330 1340 1350 1360 1370
1390 1400
pF1KB3 EDLMQVYDQFTLAPPLPSASS
:::.::::::::: : :.:
NP_001 EDLIQVYDQFTLALSLSSSS
1380 1390
>>XP_016885556 (OMIM: 400009) PREDICTED: histone demethy (1387 aa)
initn: 6737 init1: 3932 opt: 8121 Z-score: 5120.9 bits: 960.0 E(85289): 0
Smith-Waterman score: 8121; 86.6% identity (94.5% similar) in 1392 aa overlap (1-1392:1-1384)
10 20 30 40 50 60
pF1KB3 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
::::.:::.::: .::::: :::: :::: :::: : :::.::::::::.::::::::
XP_016 MKSCAVSLTTAA---VAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
:.::::::::.:::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
:::.:::::::::::::::::.::::.:::::::.:::::::::::::::::::::::::
XP_016 SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
:::.::::::::::.:::::::::::::::::::::::::::::::::::::::::: ::
XP_016 TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
::::::::::::::..::.:::::::::::::::::::::::::::::::::::::::::
XP_016 VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
::::::::::::::::::.::: :::::.::::::.::::::::::.:::::::::::::
XP_016 LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQAQLCNLPQSSLQNKTKLLPSIE
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
:::::::::::::::::::::::: ::::.::...:: :::: ..: :::::::::::::
XP_016 EAWSLPIPAELTSRQGAMNTAQQNGSDNWNGGQSLSHHPVQQ-VYSLCLTPQKLQHLEQL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
::::.::::::: .:::::::::::: ::: :::::.::: :: .::::::::::.
XP_016 RANRDNLNPAQKHQLEQLESQFVLMQ--QMRHKEVAQVRTTGIHNGAITDSSLPTNSVSN
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
.::. ::::: ::::::::::: . :..: :::: .::.::. ::::::::.:.: :.:
XP_016 RQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTILLGSNCIAG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
: :::::::::.:. :::::.:.:.::.::::..:::::.:::::.::: .::: :.::
XP_016 SESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPL
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
::: .:. ::...::.. : : ::::::: :: : .::: ::::::::::: .::::::
XP_016 FSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKP
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
: : :::::::::.: :. :.:.:: :::::. :::: ::.:::: :.:: .:::::
XP_016 SKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDS--PNLLIADNPQL
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
::::.::::.::::::::::::::::::::::.:::::::::::::::::::::: . ::
XP_016 SALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINS
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB3 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
:::::::::::::.::::. .::: :.:: :..:. . ::.::::::: :::.::::::
XP_016 VTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKAC
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB3 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
:: :::::::: ::::::::::::.:::::::::::::::::::::::::::::::::::
XP_016 RNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB3 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
:.::::::::::::::::::::::::::::::::..::::::.:::::.:::::::::::
XP_016 WRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFK
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB3 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
::::::::::::.::::::::::::::::.:::::::::.::::::::::::::::::::
XP_016 TIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPG
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB3 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
::::::::::::::::::::::::::::::: ::::::::::::::::::.:::::::::
XP_016 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDL
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB3 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_016 YEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNK
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB3 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
:.:::: ::::::::::::::::::::::::::::::. ::: :::::::.:::::.:::
XP_016 LKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLREALVAAGKEVIWH
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KB3 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM
:::..::::::::::::::.:::::::::..:::::::.::::::: .::::::::::::
XP_016 GRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCHDCARKTSKSLENFVVLEQYKM
1320 1330 1340 1350 1360 1370
1390 1400
pF1KB3 EDLMQVYDQFTLAPPLPSASS
:::.::::::::
XP_016 EDLIQVYDQFTLVSH
1380
1401 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 22:44:16 2016 done: Wed Nov 2 22:44:18 2016
Total Scan time: 14.100 Total Display time: 0.670
Function used was FASTA [36.3.4 Apr, 2011]