Result of FASTA (ccds) for
pFN21AA0943
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0943, 393 aa
1>>>pF1KA0943 393 - 393 aa - 393 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1890+/-0.0008; mu= 17.5222+/- 0.048
mean_var=69.7510+/-13.816, 0's: 0 Z-trim(108.4): 12 B-trim: 0 in 0/50
Lambda= 0.153567
statistics sampled from 10150 (10158) to 10150 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.312), width: 16
Scan time: 2.900
The best scores are: opt bits E(32554)
CCDS46564.1 ATG4B gene_id:23192|Hs108|chr2 ( 393) 2739 615.8 2.1e-176
CCDS46565.1 ATG4B gene_id:23192|Hs108|chr2 ( 380) 2589 582.6 2e-166
CCDS14538.1 ATG4A gene_id:115201|Hs108|chrX ( 398) 1507 342.9 3.1e-94
CCDS14539.1 ATG4A gene_id:115201|Hs108|chrX ( 336) 889 205.9 4.4e-53
CCDS12241.1 ATG4D gene_id:84971|Hs108|chr19 ( 474) 588 139.3 6.9e-33
>>CCDS46564.1 ATG4B gene_id:23192|Hs108|chr2 (393 aa)
initn: 2739 init1: 2739 opt: 2739 Z-score: 3280.6 bits: 615.8 E(32554): 2.1e-176
Smith-Waterman score: 2739; 99.7% identity (99.7% similar) in 393 aa overlap (1-393:1-393)
10 20 30 40 50 60
pF1KA0 MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 IGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 IGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 SYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 RLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 ETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 CQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVEQQPSHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
CCDS46 CQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLA
310 320 330 340 350 360
370 380 390
pF1KA0 CPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
:::::::::::::::::::::::::::::::::
CCDS46 CPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
370 380 390
>>CCDS46565.1 ATG4B gene_id:23192|Hs108|chr2 (380 aa)
initn: 2589 init1: 2589 opt: 2589 Z-score: 3101.2 bits: 582.6 E(32554): 2e-166
Smith-Waterman score: 2589; 99.2% identity (99.2% similar) in 372 aa overlap (1-372:1-372)
10 20 30 40 50 60
pF1KA0 MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 IGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 IGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 SYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 RLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 ETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 ETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 CQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVEQQPSHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
CCDS46 CQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLA
310 320 330 340 350 360
370 380 390
pF1KA0 CPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
::::::::: :
CCDS46 CPDVLNLSLGESCQVQILLM
370 380
>>CCDS14538.1 ATG4A gene_id:115201|Hs108|chrX (398 aa)
initn: 1517 init1: 877 opt: 1507 Z-score: 1805.3 bits: 342.9 E(32554): 3.1e-94
Smith-Waterman score: 1507; 55.4% identity (81.4% similar) in 392 aa overlap (13-393:15-398)
10 20 30 40 50
pF1KA0 MDAATLTYDTLRFAEF-EDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKN
:... :..:.:.: :::::... . :::...:::...:::::::..
CCDS14 MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA0 FPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFID
: ::::::.::.:::::::::::..::::.:::::::: : ..:.:: : .:. :.:
CCDS14 FSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 RKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVME
::: :::::.::::::::::::.:.:::::::::::::.:: :.::::...::::::.:
CCDS14 RKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA0 EIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAE---VTNRPSPWRPLVLLIPLRLGLTD
.:...::. .: .. :: .:: ... :. . .. : :.::.:..:::::...
CCDS14 DIKKMCRV-LPLSADTA----GDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQ
190 200 210 220 230
240 250 260 270 280 290
pF1KA0 INEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFI
:: .::...:.:: ::::::..:::::.:.::::..:.:::.::::::: :. .. .
CCDS14 INPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KA0 PDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVEQ
:..::: . : ::.: .::::.:.::::: : ::..::. :.: .: : :::::..
CCDS14 NDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQK-EILKENLRMFELVQK
300 310 320 330 340 350
360 370 380 390
pF1KA0 QPSHL------ACPDVLNLSLDSSD-VERLERFFDSEDEDFEILSL
.::: : :.: . . . : .:.::.: : : :::::::.
CCDS14 HPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEF-DLE-EDFEILSV
360 370 380 390
>>CCDS14539.1 ATG4A gene_id:115201|Hs108|chrX (336 aa)
initn: 1266 init1: 877 opt: 889 Z-score: 1066.4 bits: 205.9 E(32554): 4.4e-53
Smith-Waterman score: 1137; 48.1% identity (68.9% similar) in 389 aa overlap (13-393:15-336)
10 20 30 40 50
pF1KA0 MDAATLTYDTLRFAEF-EDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKN
:... :..:.:.: :::::... . :::...:::...:::::::..
CCDS14 MESVLSKYEDQITIFTDYLEEYPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA0 FPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFID
: ::::::.::.:::::::::::..::::.:::::::: : ..:.:: : .:. :.:
CCDS14 FSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEKQKEQPKEYQRILQCFLD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 RKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVME
::: :::::.::::::::::::.:.:::::::::::::.:: :.::::...::::::.:
CCDS14 RKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA0 EIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINE
.:...::. .: ..: :: .::
CCDS14 DIKKMCRV---------LPLSADT------AG----DRP---------------------
190 200
240 250 260 270 280 290
pF1KA0 AYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDE
:.:: . :.. .:::.::::::: :. .. . :.
CCDS14 ------------PDSLTA----SNQS--------DELIFLDPHTTQTFVDTEENGTVNDQ
210 220 230
300 310 320 330 340 350
pF1KA0 SFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVEQQPS
.::: . : ::.: .::::.:.::::: : ::..::. :.: .: : :::::...::
CCDS14 TFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCSLVQK-EILKENLRMFELVQKHPS
240 250 260 270 280 290
360 370 380 390
pF1KA0 HL------ACPDVLNLSLDSSD-VERLERFFDSEDEDFEILSL
: : :.: . . . : .:.::.: : : :::::::.
CCDS14 HWPPFVPPAKPEVTTTGAEFIDSTEQLEEF-DLE-EDFEILSV
300 310 320 330
>>CCDS12241.1 ATG4D gene_id:84971|Hs108|chr19 (474 aa)
initn: 565 init1: 249 opt: 588 Z-score: 703.9 bits: 139.3 E(32554): 6.9e-33
Smith-Waterman score: 656; 32.5% identity (55.6% similar) in 412 aa overlap (26-391:94-474)
10 20 30 40 50
pF1KA0 MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKD--EILSDVASRLWFT
. . ::.: . : : .. : .::::.:
CCDS12 KFKAKFLTAWNNVKYGWVVKSRTSFSKISSIHLCGRRYRFEGEGDIQRFQRDFVSRLWLT
70 80 90 100 110 120
60 70 80 90 100
pF1KA0 YRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQ-------------
::..:: . : ::: ::::::: :::..::.:. . : ::: :..
CCDS12 YRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWTWAEGMGLGPPELSGSA
130 140 150 160 170 180
110 120 130
pF1KA0 ---RKRQPDSYF------------------SVLNAFIDRKDSYYSIHQIAQMGVGEGKSI
: . : .. .... : :. . ...:.....: . ::.
CCDS12 SPSRYHGPARWMPPRWAQGAPELEQERRHRQIVSWFADHPRAPFGLHRLVELGQSSGKKA
190 200 210 220 230 240
140 150 160 170 180 190
pF1KA0 GQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADS
:.::::. ::..:.: ::. : : : . .: : :.. ::
CCDS12 GDWYGPSLVAHILRK----------AVESCSDVT------RLVVYVSQDC---TVYKADV
250 260 270 280
200 210 220 230 240 250
pF1KA0 DRHCNGFPAGAEVTNRPSP---WRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVI
: .. ::.: :. .:.:.:.::: .: .:: .:. . ::..
CCDS12 AR----------LVARPDPTAEWKSVVILVPVRLGGETLNPVYVPCVKELLRCELCLGIM
290 300 310 320 330
260 270 280 290 300 310
pF1KA0 GGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMSIAELDPS
:::: . ::::: . :.::::: ::.:. ... : : ::::: : .:..:..:::
CCDS12 GGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADF-PLESFHCTSPR-KMAFAKMDPS
340 350 360 370 380 390
320 330 340 350 360
pF1KA0 IAVGFFCKTEDDFNDWCQQVKKLSLLGGAL---PMFELVE--QQPSHLA--CPDVLNLSL
.:::. . .:. :... .. ..: ::: :.: : : : .. . .:
CCDS12 CTVGFYAGDRKEFETLCSELTRVLSSSSATERYPMFTLAEGHAQDHSLDDLCSQLAQPTL
400 410 420 430 440 450
370 380 390
pF1KA0 DSSDVERLERFFDSEDEDFEILSL
. :: : .::: .:
CCDS12 RLPRTGRLLRAKRPSSEDFVFL
460 470
393 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 20:05:04 2016 done: Wed Nov 2 20:05:05 2016
Total Scan time: 2.900 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]