Result of FASTA (omim) for
pFN21AA0474
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0474, 681 aa
1>>>pF1KA0474 681 - 681 aa - 681 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0569+/-0.000375; mu= 12.2749+/- 0.023
mean_var=131.0612+/-25.975, 0's: 0 Z-trim(116.9): 122 B-trim: 104 in 1/58
Lambda= 0.112031
statistics sampled from 28398 (28522) to 28398 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.684), E-opt: 0.2 (0.334), width: 16
Scan time: 11.720
The best scores are: opt bits E(85289)
XP_016857473 (OMIM: 600278) PREDICTED: rap1 GTPase ( 681) 4537 745.1 2e-214
XP_005246012 (OMIM: 600278) PREDICTED: rap1 GTPase ( 681) 4537 745.1 2e-214
XP_016857459 (OMIM: 600278) PREDICTED: rap1 GTPase ( 681) 4537 745.1 2e-214
NP_001139129 (OMIM: 600278) rap1 GTPase-activating ( 681) 4537 745.1 2e-214
XP_016857458 (OMIM: 600278) PREDICTED: rap1 GTPase ( 689) 4511 740.9 3.7e-213
XP_016857457 (OMIM: 600278) PREDICTED: rap1 GTPase ( 689) 4511 740.9 3.7e-213
XP_016857470 (OMIM: 600278) PREDICTED: rap1 GTPase ( 689) 4511 740.9 3.7e-213
XP_016857472 (OMIM: 600278) PREDICTED: rap1 GTPase ( 689) 4511 740.9 3.7e-213
XP_016857471 (OMIM: 600278) PREDICTED: rap1 GTPase ( 689) 4511 740.9 3.7e-213
XP_016857463 (OMIM: 600278) PREDICTED: rap1 GTPase ( 651) 3619 596.7 8.8e-170
XP_016857456 (OMIM: 600278) PREDICTED: rap1 GTPase ( 710) 3380 558.1 4e-158
XP_016857455 (OMIM: 600278) PREDICTED: rap1 GTPase ( 740) 3380 558.1 4.2e-158
XP_016857468 (OMIM: 600278) PREDICTED: rap1 GTPase ( 740) 3380 558.1 4.2e-158
XP_006710868 (OMIM: 600278) PREDICTED: rap1 GTPase ( 740) 3380 558.1 4.2e-158
XP_016857454 (OMIM: 600278) PREDICTED: rap1 GTPase ( 748) 3380 558.1 4.2e-158
XP_006710867 (OMIM: 600278) PREDICTED: rap1 GTPase ( 748) 3380 558.1 4.2e-158
NP_001317312 (OMIM: 600278) rap1 GTPase-activating ( 748) 3380 558.1 4.2e-158
XP_016857460 (OMIM: 600278) PREDICTED: rap1 GTPase ( 804) 3380 558.2 4.4e-158
XP_016857477 (OMIM: 600278) PREDICTED: rap1 GTPase ( 663) 3336 551.0 5.3e-156
XP_016857462 (OMIM: 600278) PREDICTED: rap1 GTPase ( 663) 3336 551.0 5.3e-156
NP_002876 (OMIM: 600278) rap1 GTPase-activating pr ( 663) 3336 551.0 5.3e-156
XP_016857476 (OMIM: 600278) PREDICTED: rap1 GTPase ( 663) 3336 551.0 5.3e-156
XP_016857475 (OMIM: 600278) PREDICTED: rap1 GTPase ( 663) 3336 551.0 5.3e-156
NP_001139130 (OMIM: 600278) rap1 GTPase-activating ( 727) 3336 551.0 5.7e-156
XP_016857464 (OMIM: 600278) PREDICTED: rap1 GTPase ( 655) 3325 549.2 1.8e-155
XP_016857478 (OMIM: 600278) PREDICTED: rap1 GTPase ( 655) 3325 549.2 1.8e-155
XP_016857479 (OMIM: 600278) PREDICTED: rap1 GTPase ( 655) 3325 549.2 1.8e-155
XP_016857461 (OMIM: 600278) PREDICTED: rap1 GTPase ( 655) 3325 549.2 1.8e-155
XP_016857469 (OMIM: 600278) PREDICTED: rap1 GTPase ( 719) 3325 549.2 1.9e-155
XP_016857480 (OMIM: 600278) PREDICTED: rap1 GTPase ( 625) 3315 547.6 5.3e-155
XP_016857465 (OMIM: 600278) PREDICTED: rap1 GTPase ( 625) 3315 547.6 5.3e-155
XP_016857466 (OMIM: 600278) PREDICTED: rap1 GTPase ( 617) 3312 547.1 7.3e-155
XP_016857474 (OMIM: 600278) PREDICTED: rap1 GTPase ( 681) 3312 547.1 7.9e-155
XP_016857387 (OMIM: 611609) PREDICTED: signal-indu (1704) 676 121.3 2.9e-26
XP_016857386 (OMIM: 611609) PREDICTED: signal-indu (1704) 676 121.3 2.9e-26
NP_065859 (OMIM: 611609) signal-induced proliferat (1722) 676 121.4 2.9e-26
XP_005273270 (OMIM: 611609) PREDICTED: signal-indu (1722) 676 121.4 2.9e-26
XP_016857385 (OMIM: 611609) PREDICTED: signal-indu (1722) 676 121.4 2.9e-26
XP_005273269 (OMIM: 611609) PREDICTED: signal-indu (1722) 676 121.4 2.9e-26
XP_005273268 (OMIM: 611609) PREDICTED: signal-indu (1722) 676 121.4 2.9e-26
XP_011542545 (OMIM: 611609) PREDICTED: signal-indu (1722) 676 121.4 2.9e-26
XP_016882007 (OMIM: 616655,616851) PREDICTED: sign (1780) 672 120.7 4.7e-26
XP_011524959 (OMIM: 616655,616851) PREDICTED: sign (1781) 672 120.7 4.7e-26
XP_005258728 (OMIM: 616655,616851) PREDICTED: sign (1781) 672 120.7 4.7e-26
NP_055888 (OMIM: 616655,616851) signal-induced pro (1781) 672 120.7 4.7e-26
XP_016882006 (OMIM: 616655,616851) PREDICTED: sign (1781) 672 120.7 4.7e-26
XP_011543516 (OMIM: 602180) PREDICTED: signal-indu (1042) 636 114.7 1.8e-24
XP_005274246 (OMIM: 602180) PREDICTED: signal-indu (1042) 636 114.7 1.8e-24
NP_006738 (OMIM: 602180) signal-induced proliferat (1042) 636 114.7 1.8e-24
NP_694985 (OMIM: 602180) signal-induced proliferat (1042) 636 114.7 1.8e-24
>>XP_016857473 (OMIM: 600278) PREDICTED: rap1 GTPase-act (681 aa)
initn: 4537 init1: 4537 opt: 4537 Z-score: 3970.7 bits: 745.1 E(85289): 2e-214
Smith-Waterman score: 4537; 100.0% identity (100.0% similar) in 681 aa overlap (1-681:1-681)
10 20 30 40 50 60
pF1KA0 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPDAGKLGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPDAGKLGDP
610 620 630 640 650 660
670 680
pF1KA0 ACPEIKIQLEASEQHMPQLGC
:::::::::::::::::::::
XP_016 ACPEIKIQLEASEQHMPQLGC
670 680
>>XP_005246012 (OMIM: 600278) PREDICTED: rap1 GTPase-act (681 aa)
initn: 4537 init1: 4537 opt: 4537 Z-score: 3970.7 bits: 745.1 E(85289): 2e-214
Smith-Waterman score: 4537; 100.0% identity (100.0% similar) in 681 aa overlap (1-681:1-681)
10 20 30 40 50 60
pF1KA0 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPDAGKLGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPDAGKLGDP
610 620 630 640 650 660
670 680
pF1KA0 ACPEIKIQLEASEQHMPQLGC
:::::::::::::::::::::
XP_005 ACPEIKIQLEASEQHMPQLGC
670 680
>>XP_016857459 (OMIM: 600278) PREDICTED: rap1 GTPase-act (681 aa)
initn: 4537 init1: 4537 opt: 4537 Z-score: 3970.7 bits: 745.1 E(85289): 2e-214
Smith-Waterman score: 4537; 100.0% identity (100.0% similar) in 681 aa overlap (1-681:1-681)
10 20 30 40 50 60
pF1KA0 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPDAGKLGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPDAGKLGDP
610 620 630 640 650 660
670 680
pF1KA0 ACPEIKIQLEASEQHMPQLGC
:::::::::::::::::::::
XP_016 ACPEIKIQLEASEQHMPQLGC
670 680
>>NP_001139129 (OMIM: 600278) rap1 GTPase-activating pro (681 aa)
initn: 4537 init1: 4537 opt: 4537 Z-score: 3970.7 bits: 745.1 E(85289): 2e-214
Smith-Waterman score: 4537; 100.0% identity (100.0% similar) in 681 aa overlap (1-681:1-681)
10 20 30 40 50 60
pF1KA0 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPDAGKLGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPDAGKLGDP
610 620 630 640 650 660
670 680
pF1KA0 ACPEIKIQLEASEQHMPQLGC
:::::::::::::::::::::
NP_001 ACPEIKIQLEASEQHMPQLGC
670 680
>>XP_016857458 (OMIM: 600278) PREDICTED: rap1 GTPase-act (689 aa)
initn: 4370 init1: 4329 opt: 4511 Z-score: 3947.9 bits: 740.9 E(85289): 3.7e-213
Smith-Waterman score: 4511; 98.8% identity (98.8% similar) in 689 aa overlap (1-681:1-689)
10 20 30 40 50 60
pF1KA0 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
550 560 570 580 590 600
610 620 630 640 650
pF1KA0 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSP--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHP
610 620 630 640 650 660
660 670 680
pF1KA0 DAGKLGDPACPEIKIQLEASEQHMPQLGC
:::::::::::::::::::::::::::::
XP_016 DAGKLGDPACPEIKIQLEASEQHMPQLGC
670 680
>>XP_016857457 (OMIM: 600278) PREDICTED: rap1 GTPase-act (689 aa)
initn: 4370 init1: 4329 opt: 4511 Z-score: 3947.9 bits: 740.9 E(85289): 3.7e-213
Smith-Waterman score: 4511; 98.8% identity (98.8% similar) in 689 aa overlap (1-681:1-689)
10 20 30 40 50 60
pF1KA0 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
550 560 570 580 590 600
610 620 630 640 650
pF1KA0 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSP--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHP
610 620 630 640 650 660
660 670 680
pF1KA0 DAGKLGDPACPEIKIQLEASEQHMPQLGC
:::::::::::::::::::::::::::::
XP_016 DAGKLGDPACPEIKIQLEASEQHMPQLGC
670 680
>>XP_016857470 (OMIM: 600278) PREDICTED: rap1 GTPase-act (689 aa)
initn: 4370 init1: 4329 opt: 4511 Z-score: 3947.9 bits: 740.9 E(85289): 3.7e-213
Smith-Waterman score: 4511; 98.8% identity (98.8% similar) in 689 aa overlap (1-681:1-689)
10 20 30 40 50 60
pF1KA0 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
550 560 570 580 590 600
610 620 630 640 650
pF1KA0 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSP--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHP
610 620 630 640 650 660
660 670 680
pF1KA0 DAGKLGDPACPEIKIQLEASEQHMPQLGC
:::::::::::::::::::::::::::::
XP_016 DAGKLGDPACPEIKIQLEASEQHMPQLGC
670 680
>>XP_016857472 (OMIM: 600278) PREDICTED: rap1 GTPase-act (689 aa)
initn: 4370 init1: 4329 opt: 4511 Z-score: 3947.9 bits: 740.9 E(85289): 3.7e-213
Smith-Waterman score: 4511; 98.8% identity (98.8% similar) in 689 aa overlap (1-681:1-689)
10 20 30 40 50 60
pF1KA0 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
550 560 570 580 590 600
610 620 630 640 650
pF1KA0 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSP--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHP
610 620 630 640 650 660
660 670 680
pF1KA0 DAGKLGDPACPEIKIQLEASEQHMPQLGC
:::::::::::::::::::::::::::::
XP_016 DAGKLGDPACPEIKIQLEASEQHMPQLGC
670 680
>>XP_016857471 (OMIM: 600278) PREDICTED: rap1 GTPase-act (689 aa)
initn: 4370 init1: 4329 opt: 4511 Z-score: 3947.9 bits: 740.9 E(85289): 3.7e-213
Smith-Waterman score: 4511; 98.8% identity (98.8% similar) in 689 aa overlap (1-681:1-689)
10 20 30 40 50 60
pF1KA0 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
550 560 570 580 590 600
610 620 630 640 650
pF1KA0 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSP--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHP
610 620 630 640 650 660
660 670 680
pF1KA0 DAGKLGDPACPEIKIQLEASEQHMPQLGC
:::::::::::::::::::::::::::::
XP_016 DAGKLGDPACPEIKIQLEASEQHMPQLGC
670 680
>>XP_016857463 (OMIM: 600278) PREDICTED: rap1 GTPase-act (651 aa)
initn: 4068 init1: 3611 opt: 3619 Z-score: 3169.1 bits: 596.7 E(85289): 8.8e-170
Smith-Waterman score: 4170; 93.3% identity (93.3% similar) in 689 aa overlap (1-681:1-651)
10 20 30 40 50 60
pF1KA0 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKR-
490 500 510 520 530
550 560 570 580 590 600
pF1KA0 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
:::::::::::::::::::::::
XP_016 -------------------------------------AETAAQRAEALKDFSRSSSSASS
540 550 560
610 620 630 640 650
pF1KA0 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSP--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHP
570 580 590 600 610 620
660 670 680
pF1KA0 DAGKLGDPACPEIKIQLEASEQHMPQLGC
:::::::::::::::::::::::::::::
XP_016 DAGKLGDPACPEIKIQLEASEQHMPQLGC
630 640 650
681 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 19:06:44 2016 done: Wed Nov 2 19:06:46 2016
Total Scan time: 11.720 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]