Result of FASTA (omim) for
pFN21AA0455
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0455, 763 aa
1>>>pF1KA0455 763 - 763 aa - 763 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0556+/-0.000413; mu= 6.9079+/- 0.026
mean_var=128.3410+/-26.543, 0's: 0 Z-trim(115.3): 35 B-trim: 1184 in 2/50
Lambda= 0.113212
statistics sampled from 25694 (25728) to 25694 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.302), width: 16
Scan time: 12.020
The best scores are: opt bits E(85289)
NP_055654 (OMIM: 607813) phospholipid phosphatase- ( 763) 5062 838.6 0
XP_011540800 (OMIM: 607813) PREDICTED: phospholipi ( 654) 4332 719.4 1.2e-206
NP_001159724 (OMIM: 607813) phospholipid phosphata ( 705) 2917 488.3 4.7e-137
NP_001257295 (OMIM: 610391) phospholipid phosphata ( 718) 2028 343.1 2.5e-93
XP_011526619 (OMIM: 610391) PREDICTED: phospholipi ( 746) 1040 181.7 9.7e-45
NP_079164 (OMIM: 610391) phospholipid phosphatase- ( 746) 1040 181.7 9.7e-45
XP_006714787 (OMIM: 607124) PREDICTED: phospholipi ( 221) 350 68.9 2.7e-11
NP_003702 (OMIM: 607124) phospholipid phosphatase ( 284) 350 68.9 3.4e-11
NP_795714 (OMIM: 607124) phospholipid phosphatase ( 285) 350 68.9 3.4e-11
NP_003704 (OMIM: 607125) phospholipid phosphatase ( 311) 339 67.1 1.3e-10
NP_803545 (OMIM: 607126) phospholipid phosphatase ( 232) 273 56.3 1.7e-07
NP_003703 (OMIM: 607126) phospholipid phosphatase ( 288) 273 56.3 2.1e-07
XP_011526698 (OMIM: 607126) PREDICTED: phospholipi ( 294) 273 56.3 2.1e-07
NP_808211 (OMIM: 607126) phospholipid phosphatase ( 309) 273 56.3 2.2e-07
>>NP_055654 (OMIM: 607813) phospholipid phosphatase-rela (763 aa)
initn: 5062 init1: 5062 opt: 5062 Z-score: 4474.3 bits: 838.6 E(85289): 0
Smith-Waterman score: 5062; 100.0% identity (100.0% similar) in 763 aa overlap (1-763:1-763)
10 20 30 40 50 60
pF1KA0 MQRAGSSGGRGECDISGAGRLGLEEAARLSCAVHTSPGGGRRPGQAAGMSAKERPKGKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MQRAGSSGGRGECDISGAGRLGLEEAARLSCAVHTSPGGGRRPGQAAGMSAKERPKGKVI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 KDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 INSGRKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 INSGRKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 YKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSDESMFQHRDALRSLTDLNQDPNRLLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSDESMFQHRDALRSLTDLNQDPNRLLSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 KNGSSSDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KNGSSSDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 NTPSVEDPVRRNASIHASMDSARSKQLLTQWKNKNESRKLSLQVIEPEPGQSPPRSIEMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NTPSVEDPVRRNASIHASMDSARSKQLLTQWKNKNESRKLSLQVIEPEPGQSPPRSIEMR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 SSSEPSRVGVNGDHHGPGNQYLKIQPGAVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSSEPSRVGVNGDHHGPGNQYLKIQPGAVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEET
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 QENISTSPKSSSARAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QENISTSPKSSSARAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 VSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 YELNDLNRDSESCESLKDSFGSGDRKRSNIDSNEHHHHGITTIRVTPVEGSEIGSETLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YELNDLNRDSESCESLKDSFGSGDRKRSNIDSNEHHHHGITTIRVTPVEGSEIGSETLSI
670 680 690 700 710 720
730 740 750 760
pF1KA0 SSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD
:::::::::::::::::::::::::::::::::::::::::::
NP_055 SSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD
730 740 750 760
>>XP_011540800 (OMIM: 607813) PREDICTED: phospholipid ph (654 aa)
initn: 4332 init1: 4332 opt: 4332 Z-score: 3831.0 bits: 719.4 E(85289): 1.2e-206
Smith-Waterman score: 4332; 100.0% identity (100.0% similar) in 654 aa overlap (110-763:1-654)
80 90 100 110 120 130
pF1KA0 SSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMV
::::::::::::::::::::::::::::::
XP_011 MPYIEPTQEAIPFLMLLSLAFAGPAITIMV
10 20 30
140 150 160 170 180 190
pF1KA0 GEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITDIIQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITDIIQLS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KA0 TGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFA
100 110 120 130 140 150
260 270 280 290 300 310
pF1KA0 AVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIA
160 170 180 190 200 210
320 330 340 350 360 370
pF1KA0 LYLGLYAVGNFLPSDESMFQHRDALRSLTDLNQDPNRLLSAKNGSSSDGIAHTEGILNRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYLGLYAVGNFLPSDESMFQHRDALRSLTDLNQDPNRLLSAKNGSSSDGIAHTEGILNRN
220 230 240 250 260 270
380 390 400 410 420 430
pF1KA0 HRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRANTPSVEDPVRRNASIHASM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRANTPSVEDPVRRNASIHASM
280 290 300 310 320 330
440 450 460 470 480 490
pF1KA0 DSARSKQLLTQWKNKNESRKLSLQVIEPEPGQSPPRSIEMRSSSEPSRVGVNGDHHGPGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSARSKQLLTQWKNKNESRKLSLQVIEPEPGQSPPRSIEMRSSSEPSRVGVNGDHHGPGN
340 350 360 370 380 390
500 510 520 530 540 550
pF1KA0 QYLKIQPGAVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEETQENISTSPKSSSARAKWLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYLKIQPGAVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEETQENISTSPKSSSARAKWLK
400 410 420 430 440 450
560 570 580 590 600 610
pF1KA0 AAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGSTVSCTGSIRYKTLTDHEPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGSTVSCTGSIRYKTLTDHEPSG
460 470 480 490 500 510
620 630 640 650 660 670
pF1KA0 IVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQTYELNDLNRDSESCESLKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQTYELNDLNRDSESCESLKDS
520 530 540 550 560 570
680 690 700 710 720 730
pF1KA0 FGSGDRKRSNIDSNEHHHHGITTIRVTPVEGSEIGSETLSISSSRDSTLRRKGNIILIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGSGDRKRSNIDSNEHHHHGITTIRVTPVEGSEIGSETLSISSSRDSTLRRKGNIILIPE
580 590 600 610 620 630
740 750 760
pF1KA0 RSNSPENTRNIFYKGTSPTRAYKD
::::::::::::::::::::::::
XP_011 RSNSPENTRNIFYKGTSPTRAYKD
640 650
>>NP_001159724 (OMIM: 607813) phospholipid phosphatase-r (705 aa)
initn: 4658 init1: 2914 opt: 2917 Z-score: 2581.5 bits: 488.3 E(85289): 4.7e-137
Smith-Waterman score: 4546; 92.4% identity (92.4% similar) in 763 aa overlap (1-763:1-705)
10 20 30 40 50 60
pF1KA0 MQRAGSSGGRGECDISGAGRLGLEEAARLSCAVHTSPGGGRRPGQAAGMSAKERPKGKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQRAGSSGGRGECDISGAGRLGLEEAARLSCAVHTSPGGGRRPGQAAGMSAKERPKGKVI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 KDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDSVTLLPCFYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 PFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFLMLLSLAFAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 VHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHVFGLCSTALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 INSGRKSFPSQHATLAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQ
::::::::::::::::::::::::
NP_001 INSGRKSFPSQHATLAAFAAVYVS------------------------------------
250 260
310 320 330 340 350 360
pF1KA0 YKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPSDESMFQHRDALRSLTDLNQDPNRLLSA
::::::::::::::::::::::::::::::::::::::
NP_001 ----------------------GLYAVGNFLPSDESMFQHRDALRSLTDLNQDPNRLLSA
270 280 290 300
370 380 390 400 410 420
pF1KA0 KNGSSSDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNGSSSDGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRA
310 320 330 340 350 360
430 440 450 460 470 480
pF1KA0 NTPSVEDPVRRNASIHASMDSARSKQLLTQWKNKNESRKLSLQVIEPEPGQSPPRSIEMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTPSVEDPVRRNASIHASMDSARSKQLLTQWKNKNESRKLSLQVIEPEPGQSPPRSIEMR
370 380 390 400 410 420
490 500 510 520 530 540
pF1KA0 SSSEPSRVGVNGDHHGPGNQYLKIQPGAVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSEPSRVGVNGDHHGPGNQYLKIQPGAVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEET
430 440 450 460 470 480
550 560 570 580 590 600
pF1KA0 QENISTSPKSSSARAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QENISTSPKSSSARAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEGST
490 500 510 520 530 540
610 620 630 640 650 660
pF1KA0 VSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLRQT
550 560 570 580 590 600
670 680 690 700 710 720
pF1KA0 YELNDLNRDSESCESLKDSFGSGDRKRSNIDSNEHHHHGITTIRVTPVEGSEIGSETLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YELNDLNRDSESCESLKDSFGSGDRKRSNIDSNEHHHHGITTIRVTPVEGSEIGSETLSI
610 620 630 640 650 660
730 740 750 760
pF1KA0 SSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD
:::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD
670 680 690 700
>>NP_001257295 (OMIM: 610391) phospholipid phosphatase-r (718 aa)
initn: 1846 init1: 885 opt: 2028 Z-score: 1796.6 bits: 343.1 E(85289): 2.5e-93
Smith-Waterman score: 2033; 48.5% identity (74.0% similar) in 722 aa overlap (49-745:2-703)
20 30 40 50 60 70
pF1KA0 GRLGLEEAARLSCAVHTSPGGGRRPGQAAGMSAKERPKGKVIKDSVTLLPCFYFVELPIL
.:.:: :.:. :::.:::::::::::::.
NP_001 MISTKE--KNKIPKDSMTLLPCFYFVELPIV
10 20
80 90 100 110 120 130
pF1KA0 ASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIM
:::.::::::::::.:::.. ::.::::.:::::.: ..: ::.:::::::::.:: .::
NP_001 ASSIVSLYFLELTDLFKPAKVGFQCYDRTLSMPYVETNEELIPLLMLLSLAFAAPAASIM
30 40 50 60 70 80
140 150 160 170 180 190
pF1KA0 VGEGILYCCLSK---RRNG-VGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITD
:.::.::: :. : .: .: : .::::::::::::::.::::::::::::.:::.::
NP_001 VAEGMLYCLQSRLWGRAGGPAGAEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTD
90 100 110 120 130 140
200 210 220 230 240 250
pF1KA0 IIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHAT
.:::.:::..:.:::::::::: :..::. : ::..::::: :. .: :.::.:::::::
NP_001 VIQLATGYHTPFFLTVCKPNYTLLGTSCEVNPYITQDICSGHDIHAILSARKTFPSQHAT
150 160 170 180 190 200
260 270 280 290 300 310
pF1KA0 LAAFAAVYVSMYFNSTLTDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLI
:.:::::::::::::...:..:::::.:::.: : . .::::.::::..:::::: ::::
NP_001 LSAFAAVYVSMYFNSVISDTTKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFLI
210 220 230 240 250 260
320 330 340 350 360 370
pF1KA0 GGGIALYLGLYAVGNFL--PSDESMFQH--RDALRSLTDLNQDPNRLLSAKNGSSSDGIA
:.::: ::. .::::: :... .::::.::. ..: . . ... :.: ..
NP_001 GAGIAAYLACHAVGNFQAPPAEKPAAPAPAKDALRALTQRGHDS--VYQQNKSVSTDELG
270 280 290 300 310 320
380 390 400 410 420
pF1KA0 ---HTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRANTPSVED
. :: :. .:: .::::..::....:::::.::::::::.:::::..::..:
NP_001 PPGRLEGAPRPVAREKTSLGSLKRASVDVDLLAPRSPMAKENMVTFSHTLPRASAPSLDD
330 340 350 360 370 380
430 440 450 460 470 480
pF1KA0 PVRRNASIHASMDSARSKQLLTQWKNKN-ESRKLSLQVIEPEPGQ--SPPRSI----EMR
:.::. .::. .:..:::::...::.:. :.: :.: . ::. .: . . : .
NP_001 PARRHMTIHVPLDASRSKQLISEWKQKSLEGRGLGLPD-DASPGHLRAPAEPMAEEEEEE
390 400 410 420 430 440
490 500 510 520 530
pF1KA0 SSSEPSRVGVNGDHHGPGNQYLKIQPGAVPGCNNSMPGGPRVSIQSRPGSSQLVHIPEE-
. : . . . .::. : : :: :::: . : : :::::::
NP_001 EDEEEEEEEEEEEDEGPAPPSLYPTVQARPGL------GPRVILPPRAGPPPLVHIPEEG
450 460 470 480 490 500
540 550 560 570 580 590
pF1KA0 TQENISTSPKSSSA-RAKWLKAAEKTVACNRSNSQPRIMQVIAMSKQQGVLQSSPKNTEG
.: . . ::::... ::::: :::. : . ::..::::::: :. . .: .
NP_001 AQTGAGLSPKSGAGVRAKWLMMAEKSGAA--VANPPRLLQVIAMSKAPGAPGPKAAETAS
510 520 530 540 550
600 610 620 630 640 650
pF1KA0 STVSCTGSIRYKTLTDHEPSGIVRVEAHPENNRPIIQIPSTEGEGSGSWKWKAPEKGSLR
:. . . : .:.. .:.. ..:: ..:: .. :.... . :.. :.::: :.
NP_001 SSSASSDSSQYRSPSDRDSASIVTIDAHAPHH-PVVHLSA----GGAPWEWKAAGGGAKA
560 570 580 590 600 610
660 670 680 690 700 710
pF1KA0 QT---YELNDLNRDSESCESLKDSFGSGDRKRSNIDSNEHHHHGITTIRVTPVEG-SEIG
.. :::.:: : .. . : : . :..:..: . ...:. .. :: .:
NP_001 EADGGYELGDLARGFRG--GAKPPGVSPGSSVSDVDQEEPRFGAVATVNLATGEGLPPLG
620 630 640 650 660 670
720 730 740 750 760
pF1KA0 SETLSIS-SSRDSTLRRKGNIILIPERSNSPENTRNIFYKGTSPTRAYKD
. ... .::.:::::... . . :: :
NP_001 AADGALGPGSRESTLRRHAGGLGLAEREAEAEAEGYFRKMQARRFPD
680 690 700 710
>>XP_011526619 (OMIM: 610391) PREDICTED: phospholipid ph (746 aa)
initn: 1531 init1: 570 opt: 1040 Z-score: 924.2 bits: 181.7 E(85289): 9.7e-45
Smith-Waterman score: 1967; 46.7% identity (71.2% similar) in 750 aa overlap (49-745:2-731)
20 30 40 50 60 70
pF1KA0 GRLGLEEAARLSCAVHTSPGGGRRPGQAAGMSAKERPKGKVIKDSVTLLPCFYFVELPIL
.:.:: :.:. :::.:::::::::::::.
XP_011 MISTKE--KNKIPKDSMTLLPCFYFVELPIV
10 20
80 90 100 110 120 130
pF1KA0 ASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIM
:::.::::::::::.:::.. ::.::::.:::::.: ..: ::.:::::::::.:: .::
XP_011 ASSIVSLYFLELTDLFKPAKVGFQCYDRTLSMPYVETNEELIPLLMLLSLAFAAPAASIM
30 40 50 60 70 80
140 150 160 170 180 190
pF1KA0 VGEGILYCCLSK---RRNG-VGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITD
:.::.::: :. : .: .: : .::::::::::::::.::::::::::::.:::.::
XP_011 VAEGMLYCLQSRLWGRAGGPAGAEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTD
90 100 110 120 130 140
200 210 220 230 240 250
pF1KA0 IIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHAT
.:::.:::..:.:::::::::: :..::. : ::..::::: :. .: :.::.:::::::
XP_011 VIQLATGYHTPFFLTVCKPNYTLLGTSCEVNPYITQDICSGHDIHAILSARKTFPSQHAT
150 160 170 180 190 200
260 270 280
pF1KA0 LAAFAAVYVS----------------------------MYFNSTLTDSSKLLKPLLVFTF
:.:::::::: :::::...:..:::::.:::.:
XP_011 LSAFAAVYVSVSPAPHCPSQALLLTRGEPSLTPTPMPQMYFNSVISDTTKLLKPILVFAF
210 220 230 240 250 260
290 300 310 320 330 340
pF1KA0 IICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFL--PSDESMFQH--RD
: . .::::.::::..:::::: :::::.::: ::. .::::: :... .:
XP_011 AIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHAVGNFQAPPAEKPAAPAPAKD
270 280 290 300 310 320
350 360 370 380 390
pF1KA0 ALRSLTDLNQDPNRLLSAKNGSSSDGIA---HTEGILNRNHRDASSLTNLKRANADVEII
:::.::. ..: . . ... :.: .. . :: :. .:: .::::..::...
XP_011 ALRALTQRGHDS--VYQQNKSVSTDELGPPGRLEGAPRPVAREKTSLGSLKRASVDVDLL
330 340 350 360 370 380
400 410 420 430 440 450
pF1KA0 TPRSPMGKENMVTFSNTLPRANTPSVEDPVRRNASIHASMDSARSKQLLTQWKNKN-ESR
.:::::.::::::::.:::::..::..::.::. .::. .:..:::::...::.:. :.:
XP_011 APRSPMAKENMVTFSHTLPRASAPSLDDPARRHMTIHVPLDASRSKQLISEWKQKSLEGR
390 400 410 420 430 440
460 470 480 490 500 510
pF1KA0 KLSLQVIEPEPGQ--SPPRSI----EMRSSSEPSRVGVNGDHHGPGNQYLKIQPGAVPGC
:.: . ::. .: . . : . . : . . . .::. : : ::
XP_011 GLGLPD-DASPGHLRAPAEPMAEEEEEEEDEEEEEEEEEEEDEGPAPPSLYPTVQARPGL
450 460 470 480 490 500
520 530 540 550 560 570
pF1KA0 NNSMPGGPRVSIQSRPGSSQLVHIPEE-TQENISTSPKSSSA-RAKWLKAAEKTVACNRS
:::: . : : ::::::: .: . . ::::... ::::: :::. :
XP_011 ------GPRVILPPRAGPPPLVHIPEEGAQTGAGLSPKSGAGVRAKWLMMAEKSGAA--V
510 520 530 540 550
580 590 600 610 620 630
pF1KA0 NSQPRIMQVIAMSKQQGVLQSSPKNTEGSTVSCTGSIRYKTLTDHEPSGIVRVEAHPENN
. ::..::::::: :. . .: .:. . . : .:.. .:.. ..:: ..:: ..
XP_011 ANPPRLLQVIAMSKAPGAPGPKAAETASSSSASSDSSQYRSPSDRDSASIVTIDAHAPHH
560 570 580 590 600 610
640 650 660 670 680
pF1KA0 RPIIQIPSTEGEGSGSWKWKAPEKGSLRQT---YELNDLNRDSESCESLKDSFGSGDRKR
:.... . :.. :.::: :. .. :::.:: : .. . : : .
XP_011 -PVVHLSA----GGAPWEWKAAGGGAKAEADGGYELGDLARGFRG--GAKPPGVSPGSSV
620 630 640 650 660 670
690 700 710 720 730 740
pF1KA0 SNIDSNEHHHHGITTIRVTPVEG-SEIGSETLSIS-SSRDSTLRRKGNIILIPERSNSPE
:..:..: . ...:. .. :: .:. ... .::.:::::... . . :: :
XP_011 SDVDQEEPRFGAVATVNLATGEGLPPLGAADGALGPGSRESTLRRHAGGLGLAEREAEAE
680 690 700 710 720 730
750 760
pF1KA0 NTRNIFYKGTSPTRAYKD
XP_011 AEGYFRKMQARRFPD
740
>>NP_079164 (OMIM: 610391) phospholipid phosphatase-rela (746 aa)
initn: 1531 init1: 570 opt: 1040 Z-score: 924.2 bits: 181.7 E(85289): 9.7e-45
Smith-Waterman score: 1967; 46.7% identity (71.2% similar) in 750 aa overlap (49-745:2-731)
20 30 40 50 60 70
pF1KA0 GRLGLEEAARLSCAVHTSPGGGRRPGQAAGMSAKERPKGKVIKDSVTLLPCFYFVELPIL
.:.:: :.:. :::.:::::::::::::.
NP_079 MISTKE--KNKIPKDSMTLLPCFYFVELPIV
10 20
80 90 100 110 120 130
pF1KA0 ASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIM
:::.::::::::::.:::.. ::.::::.:::::.: ..: ::.:::::::::.:: .::
NP_079 ASSIVSLYFLELTDLFKPAKVGFQCYDRTLSMPYVETNEELIPLLMLLSLAFAAPAASIM
30 40 50 60 70 80
140 150 160 170 180 190
pF1KA0 VGEGILYCCLSK---RRNG-VGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITD
:.::.::: :. : .: .: : .::::::::::::::.::::::::::::.:::.::
NP_079 VAEGMLYCLQSRLWGRAGGPAGAEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTD
90 100 110 120 130 140
200 210 220 230 240 250
pF1KA0 IIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHAT
.:::.:::..:.:::::::::: :..::. : ::..::::: :. .: :.::.:::::::
NP_079 VIQLATGYHTPFFLTVCKPNYTLLGTSCEVNPYITQDICSGHDIHAILSARKTFPSQHAT
150 160 170 180 190 200
260 270 280
pF1KA0 LAAFAAVYVS----------------------------MYFNSTLTDSSKLLKPLLVFTF
:.:::::::: :::::...:..:::::.:::.:
NP_079 LSAFAAVYVSVSPAPHCPSQALLLTRGEPSLTPTPMPQMYFNSVISDTTKLLKPILVFAF
210 220 230 240 250 260
290 300 310 320 330 340
pF1KA0 IICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFL--PSDESMFQH--RD
: . .::::.::::..:::::: :::::.::: ::. .::::: :... .:
NP_079 AIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHAVGNFQAPPAEKPAAPAPAKD
270 280 290 300 310 320
350 360 370 380 390
pF1KA0 ALRSLTDLNQDPNRLLSAKNGSSSDGIA---HTEGILNRNHRDASSLTNLKRANADVEII
:::.::. ..: . . ... :.: .. . :: :. .:: .::::..::...
NP_079 ALRALTQRGHDS--VYQQNKSVSTDELGPPGRLEGAPRPVAREKTSLGSLKRASVDVDLL
330 340 350 360 370 380
400 410 420 430 440 450
pF1KA0 TPRSPMGKENMVTFSNTLPRANTPSVEDPVRRNASIHASMDSARSKQLLTQWKNKN-ESR
.:::::.::::::::.:::::..::..::.::. .::. .:..:::::...::.:. :.:
NP_079 APRSPMAKENMVTFSHTLPRASAPSLDDPARRHMTIHVPLDASRSKQLISEWKQKSLEGR
390 400 410 420 430 440
460 470 480 490 500 510
pF1KA0 KLSLQVIEPEPGQ--SPPRSI----EMRSSSEPSRVGVNGDHHGPGNQYLKIQPGAVPGC
:.: . ::. .: . . : . . : . . . .::. : : ::
NP_079 GLGLPD-DASPGHLRAPAEPMAEEEEEEEDEEEEEEEEEEEDEGPAPPSLYPTVQARPGL
450 460 470 480 490 500
520 530 540 550 560 570
pF1KA0 NNSMPGGPRVSIQSRPGSSQLVHIPEE-TQENISTSPKSSSA-RAKWLKAAEKTVACNRS
:::: . : : ::::::: .: . . ::::... ::::: :::. :
NP_079 ------GPRVILPPRAGPPPLVHIPEEGAQTGAGLSPKSGAGVRAKWLMMAEKSGAA--V
510 520 530 540 550
580 590 600 610 620 630
pF1KA0 NSQPRIMQVIAMSKQQGVLQSSPKNTEGSTVSCTGSIRYKTLTDHEPSGIVRVEAHPENN
. ::..::::::: :. . .: .:. . . : .:.. .:.. ..:: ..:: ..
NP_079 ANPPRLLQVIAMSKAPGAPGPKAAETASSSSASSDSSQYRSPSDRDSASIVTIDAHAPHH
560 570 580 590 600 610
640 650 660 670 680
pF1KA0 RPIIQIPSTEGEGSGSWKWKAPEKGSLRQT---YELNDLNRDSESCESLKDSFGSGDRKR
:.... . :.. :.::: :. .. :::.:: : .. . : : .
NP_079 -PVVHLSA----GGAPWEWKAAGGGAKAEADGGYELGDLARGFRG--GAKPPGVSPGSSV
620 630 640 650 660 670
690 700 710 720 730 740
pF1KA0 SNIDSNEHHHHGITTIRVTPVEG-SEIGSETLSIS-SSRDSTLRRKGNIILIPERSNSPE
:..:..: . ...:. .. :: .:. ... .::.:::::... . . :: :
NP_079 SDVDQEEPRFGAVATVNLATGEGLPPLGAADGALGPGSRESTLRRHAGGLGLAEREAEAE
680 690 700 710 720 730
750 760
pF1KA0 NTRNIFYKGTSPTRAYKD
NP_079 AEGYFRKMQARRFPD
740
>>XP_006714787 (OMIM: 607124) PREDICTED: phospholipid ph (221 aa)
initn: 282 init1: 134 opt: 350 Z-score: 323.8 bits: 68.9 E(85289): 2.7e-11
Smith-Waterman score: 350; 31.3% identity (63.6% similar) in 198 aa overlap (166-354:18-209)
140 150 160 170 180
pF1KA0 TIMVGEGILYCCLSKRRNGVGLEPNINAGGCNF---NSFLRRAV-----RFVGVHVFGLC
::. :::.: . .:. .::
XP_006 MCSACCWIILGETLSVYCNLLHSNSFIRNNYIATIYKAIGTFLFGAA
10 20 30 40
190 200 210 220 230 240
pF1KA0 STALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKS
.. .::: . : : :.:: :: :.....: : ..:: :: : . .. :: :
XP_006 ASQSLTDIAKYSIGRLRPHFLDVCDPDWSKINCS---DGYIEYYICRG-NAERVKEGRLS
50 60 70 80 90 100
250 260 270 280 290 300
pF1KA0 FPSQHATLAAFAAVYVSMYFNSTLT-DSSKLLKPLLVFTFIICGIICGLTRITQYKNHPV
: : :.... . ..:..:... . : ..::.: : : .. .: ::.:...::.:
XP_006 FYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWS
110 120 130 140 150 160
310 320 330 340 350 360
pF1KA0 DVYCGFLIGGGIALYLGLYAVGNFLPSDESMFQHRDALRSLTDLNQDPNRLLSAKNGSSS
:: :.. :. .:. ...: :..:. .... :..: : : :.. :
XP_006 DVLTGLIQGALVAILVAVY-VSDFF-KERTSFKERKEEDSHTTLHETPTTGNHYPSNHQP
170 180 190 200 210 220
370 380 390 400 410 420
pF1KA0 DGIAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRANTPSVE
>>NP_003702 (OMIM: 607124) phospholipid phosphatase 1 is (284 aa)
initn: 229 init1: 134 opt: 350 Z-score: 322.0 bits: 68.9 E(85289): 3.4e-11
Smith-Waterman score: 439; 29.5% identity (60.6% similar) in 292 aa overlap (65-354:5-272)
40 50 60 70 80 90
pF1KA0 TSPGGGRRPGQAAGMSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTDVF
: :: .: : .: ...: : ::.
NP_003 MFDKTRLP---YVALDVLCVLLAGLPFAILTSRH
10 20 30
100 110 120 130 140 150
pF1KA0 KPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVGEGI-LYCCLSKRRN
: . : : :.:...:: : : ::. .: .. . :.:..:: . .:: :
NP_003 TPFQRGVFCNDESIKYPYKEDT---IPYALLGGIIIPFSIIVIILGETLSVYCNL-----
40 50 60 70 80
160 170 180 190 200 210
pF1KA0 GVGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVCKP
..... :... . .:. .:: .. .::: . : : :.:: :: :
NP_003 -------LHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGRLRPHFLDVCDP
90 100 110 120 130
220 230 240 250 260 270
pF1KA0 NYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSMYFNSTLT-
.....: : ..:: :: : . .. :: :: : :.... . ..:..:... .
NP_003 DWSKINCS---DGYIEYYICRG-NAERVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKG
140 150 160 170 180 190
280 290 300 310 320 330
pF1KA0 DSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFLP
: ..::.: : : .. .: ::.:...::.: :: :.. :. .:. ...: :..:.
NP_003 DWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAILVAVY-VSDFF-
200 210 220 230 240 250
340 350 360 370 380 390
pF1KA0 SDESMFQHRDALRSLTDLNQDPNRLLSAKNGSSSDGIAHTEGILNRNHRDASSLTNLKRA
.... :..: : : :.. :
NP_003 KERTSFKERKEEDSHTTLHETPTTGNHYPSNHQP
260 270 280
>>NP_795714 (OMIM: 607124) phospholipid phosphatase 1 is (285 aa)
initn: 274 init1: 134 opt: 350 Z-score: 322.0 bits: 68.9 E(85289): 3.4e-11
Smith-Waterman score: 418; 28.6% identity (61.6% similar) in 294 aa overlap (65-354:5-273)
40 50 60 70 80 90
pF1KA0 TSPGGGRRPGQAAGMSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYF--LELTD
: :: .: : .: ..:. . :.: .
NP_795 MFDKTRLP---YVALDVLCVLLASMPMAVLKLGQ
10 20 30
100 110 120 130 140 150
pF1KA0 VFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITIMVGEGI-LYCCLSKR
.. : . :: : : :...:: . : . :.:..... : .:..:: . .:: :
NP_795 IY-PFQRGFFCKDNSINYPYHDSTVTST-VLILVGVGL--PISSIILGETLSVYCNL---
40 50 60 70 80
160 170 180 190 200 210
pF1KA0 RNGVGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFLTVC
..... :... . .:. .:: .. .::: . : : :.:: ::
NP_795 ---------LHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGRLRPHFLDVC
90 100 110 120 130
220 230 240 250 260 270
pF1KA0 KPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSMYFNSTL
:.....: : ..:: :: : . .. :: :: : :.... . ..:..:... .
NP_795 DPDWSKINCS---DGYIEYYICRG-NAERVKEGRLSFYSGHSSFSMYCMLFVALYLQARM
140 150 160 170 180 190
280 290 300 310 320 330
pF1KA0 T-DSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNF
: ..::.: : : .. .: ::.:...::.: :: :.. :. .:. ...: :..:
NP_795 KGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAILVAVY-VSDF
200 210 220 230 240 250
340 350 360 370 380 390
pF1KA0 LPSDESMFQHRDALRSLTDLNQDPNRLLSAKNGSSSDGIAHTEGILNRNHRDASSLTNLK
. .... :..: : : :.. :
NP_795 F-KERTSFKERKEEDSHTTLHETPTTGNHYPSNHQP
260 270 280
>>NP_003704 (OMIM: 607125) phospholipid phosphatase 3 [H (311 aa)
initn: 412 init1: 133 opt: 339 Z-score: 311.7 bits: 67.1 E(85289): 1.3e-10
Smith-Waterman score: 407; 28.3% identity (61.6% similar) in 307 aa overlap (42-345:15-292)
20 30 40 50 60
pF1KA0 ECDISGAGRLGLEEAARLSCAVHTSPGGGRRPGQAAGMSAKERPKG--KVIKDSVTLLPC
. : . ... . : .: .:. . :. :
NP_003 MQNYKYDKAIVPESKNGGSPALNNNPRRSGSKRVLLICLDLF-C
10 20 30 40
70 80 90 100 110 120
pF1KA0 FYFVELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLA
.... ::.: ..: :...:: : :: : :.:...: : :.: .: ...
NP_003 LFMAGLPFL--------IIE-TSTIKPYHRGFYCNDESIKYPL--KTGETINDAVLCAVG
50 60 70 80 90
130 140 150 160 170 180
pF1KA0 FAGPAITIMVGEGILYCCLSKRRNGVGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCST
.. ..:..:: :.: :. . : .. . :: .:: .
NP_003 IVIAILAIITGEFYRIYYLKKSRSTIQ------------NPYVAALYKQVGCFLFGCAIS
100 110 120 130 140
190 200 210 220 230 240
pF1KA0 ALITDIIQLSTGYQAPYFLTVCKPNYTSLNVSCKENSYIVEDICSGSDLTVINSGRKSFP
.::: ..: : :.::.::.:.....: :.:. :: . : :.: . .. .::::
NP_003 QSFTDIAKVSIGRLRPHFLSVCNPDFSQIN--CSEG-YIQNYRCRGDD-SKVQEARKSFF
150 160 170 180 190
250 260 270 280 290 300
pF1KA0 SQHATLAAFAAVYVSMYFNSTLT-DSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDV
: ::... .. .:. .:... .: ...::.::: ::.:. .. ::.:....:.:: ::
NP_003 SGHASFSMYTMLYLVLYLQARFTWRGARLLRPLLQFTLIMMAFYTGLSRVSDHKHHPSDV
200 210 220 230 240 250
310 320 330 340 350 360
pF1KA0 YCGFLIGGGIALYLGLYAVGNFLPSDESMFQHRDALRSLTDLNQDPNRLLSAKNGSSSDG
:: :. .: . .. :.... . .. :.:
NP_003 LAGFAQGALVACCI-VFFVSDLFKTKTTLSLPAPAIRKEILSPVDIIDRNNHHNMM
260 270 280 290 300 310
370 380 390 400 410 420
pF1KA0 IAHTEGILNRNHRDASSLTNLKRANADVEIITPRSPMGKENMVTFSNTLPRANTPSVEDP
763 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:58:38 2016 done: Wed Nov 2 18:58:40 2016
Total Scan time: 12.020 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]