Result of FASTA (omim) for
pFN21AA0369
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0369, 729 aa
1>>>pF1KA0369 729 - 729 aa - 729 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6550+/-0.000595; mu= -8.2884+/- 0.037
mean_var=590.9469+/-129.538, 0's: 0 Z-trim(118.3): 1790 B-trim: 0 in 0/56
Lambda= 0.052759
statistics sampled from 28775 (31130) to 28775 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.365), width: 16
Scan time: 12.430
The best scores are: opt bits E(85289)
NP_004725 (OMIM: 604742) serine/threonine-protein ( 729) 4795 381.1 8.8e-105
NP_001317000 (OMIM: 604742) serine/threonine-prote ( 740) 4490 357.9 8.6e-98
NP_001317001 (OMIM: 604742) serine/threonine-prote ( 740) 4490 357.9 8.6e-98
XP_016876336 (OMIM: 604742) PREDICTED: serine/thre ( 708) 4489 357.8 8.9e-98
NP_001182344 (OMIM: 604742) serine/threonine-prote ( 422) 2768 226.5 1.8e-58
XP_005262842 (OMIM: 613166) PREDICTED: serine/thre ( 782) 2497 206.2 4.1e-52
NP_001035350 (OMIM: 613166) serine/threonine-prote ( 766) 2485 205.3 7.7e-52
NP_001182345 (OMIM: 604742) serine/threonine-prote ( 433) 2463 203.3 1.7e-51
XP_005262843 (OMIM: 613166) PREDICTED: serine/thre ( 765) 2434 201.4 1.1e-50
NP_001035351 (OMIM: 613166) serine/threonine-prote ( 783) 2433 201.3 1.2e-50
XP_016863321 (OMIM: 613166) PREDICTED: serine/thre ( 717) 2419 200.2 2.4e-50
XP_016876337 (OMIM: 604742) PREDICTED: serine/thre ( 363) 2250 187.0 1.2e-46
NP_000546 (OMIM: 300067,300121) neuronal migration ( 441) 1689 144.4 9.5e-34
NP_835364 (OMIM: 300067,300121) neuronal migration ( 360) 1678 143.4 1.5e-33
NP_835366 (OMIM: 300067,300121) neuronal migration ( 360) 1678 143.4 1.5e-33
XP_011529180 (OMIM: 300067,300121) PREDICTED: neur ( 361) 1678 143.4 1.5e-33
NP_835365 (OMIM: 300067,300121) neuronal migration ( 365) 1674 143.1 1.9e-33
NP_001182482 (OMIM: 300067,300121) neuronal migrat ( 366) 1674 143.1 1.9e-33
XP_016884801 (OMIM: 300067,300121) PREDICTED: neur ( 366) 1674 143.1 1.9e-33
XP_011529182 (OMIM: 300067,300121) PREDICTED: neur ( 319) 1552 133.8 1.1e-30
XP_011529181 (OMIM: 300067,300121) PREDICTED: neur ( 324) 1551 133.7 1.1e-30
NP_208382 (OMIM: 613167) serine/threonine-protein ( 648) 1063 96.9 2.7e-19
XP_011532469 (OMIM: 613167) PREDICTED: serine/thre ( 648) 1063 96.9 2.7e-19
XP_011529410 (OMIM: 300680) PREDICTED: calcium/cal ( 361) 854 80.7 1.1e-14
XP_011529409 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 851 80.4 1.3e-14
XP_011529412 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 851 80.4 1.3e-14
XP_006724872 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 851 80.4 1.3e-14
XP_011529414 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 851 80.4 1.3e-14
XP_016884767 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 851 80.4 1.3e-14
XP_016884768 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 851 80.4 1.3e-14
XP_011529413 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 851 80.4 1.3e-14
XP_005274708 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 851 80.4 1.3e-14
NP_001129212 (OMIM: 300680) calcium/calmodulin-dep ( 360) 851 80.5 1.3e-14
NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370) 850 80.4 1.4e-14
XP_016884766 (OMIM: 300680) PREDICTED: calcium/cal ( 426) 851 80.6 1.5e-14
NP_001034671 (OMIM: 300680) calcium/calmodulin-dep ( 426) 851 80.6 1.5e-14
XP_005265573 (OMIM: 604998) PREDICTED: calcium/cal ( 413) 850 80.5 1.5e-14
XP_006717545 (OMIM: 607957) PREDICTED: calcium/cal ( 362) 847 80.2 1.7e-14
XP_006717546 (OMIM: 607957) PREDICTED: calcium/cal ( 355) 841 79.7 2.2e-14
NP_065130 (OMIM: 607957) calcium/calmodulin-depend ( 357) 841 79.7 2.3e-14
XP_016863322 (OMIM: 613166) PREDICTED: serine/thre ( 694) 848 80.6 2.3e-14
NP_705718 (OMIM: 607957) calcium/calmodulin-depend ( 385) 841 79.7 2.4e-14
XP_006717544 (OMIM: 607957) PREDICTED: calcium/cal ( 366) 824 78.4 5.6e-14
XP_011517893 (OMIM: 607957) PREDICTED: calcium/cal ( 372) 824 78.4 5.7e-14
NP_001310303 (OMIM: 114080) calcium/calmodulin-dep ( 473) 790 76.0 3.9e-13
NP_001735 (OMIM: 114080) calcium/calmodulin-depend ( 473) 790 76.0 3.9e-13
NP_001310304 (OMIM: 114080) calcium/calmodulin-dep ( 473) 790 76.0 3.9e-13
XP_016862843 (OMIM: 604998) PREDICTED: calcium/cal ( 326) 761 73.6 1.4e-12
XP_005265574 (OMIM: 604998) PREDICTED: calcium/cal ( 369) 761 73.6 1.6e-12
XP_016857355 (OMIM: 614994) PREDICTED: calcium/cal ( 476) 761 73.8 1.8e-12
>>NP_004725 (OMIM: 604742) serine/threonine-protein kina (729 aa)
initn: 4795 init1: 4795 opt: 4795 Z-score: 2002.2 bits: 381.1 E(85289): 8.8e-105
Smith-Waterman score: 4795; 100.0% identity (100.0% similar) in 729 aa overlap (1-729:1-729)
10 20 30 40 50 60
pF1KA0 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 VAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGR
670 680 690 700 710 720
pF1KA0 FSDEDATRM
:::::::::
NP_004 FSDEDATRM
>>NP_001317000 (OMIM: 604742) serine/threonine-protein k (740 aa)
initn: 4489 init1: 4489 opt: 4490 Z-score: 1876.6 bits: 357.9 E(85289): 8.6e-98
Smith-Waterman score: 4490; 96.3% identity (97.0% similar) in 723 aa overlap (1-715:1-718)
10 20 30 40 50 60
pF1KA0 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
610 620 630 640 650 660
670 680 690 700 710
pF1KA0 VAGKIKKHFNTGPKPNSTAAGVSVIA---LDHGFTI-KRSGSLD----YYQQPGMYWIRP
:::::::::::::::::::::::::: ::. . .: . : : ::. :
NP_001 VAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNQDVRSRYKAQPA-----P
670 680 690 700 710
720
pF1KA0 PLLIRRGRFSDEDATRM
: :
NP_001 PELNSESEDYSPSSSETVRSPNSPF
720 730 740
>>NP_001317001 (OMIM: 604742) serine/threonine-protein k (740 aa)
initn: 4489 init1: 4489 opt: 4490 Z-score: 1876.6 bits: 357.9 E(85289): 8.6e-98
Smith-Waterman score: 4490; 96.3% identity (97.0% similar) in 723 aa overlap (1-715:1-718)
10 20 30 40 50 60
pF1KA0 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
610 620 630 640 650 660
670 680 690 700 710
pF1KA0 VAGKIKKHFNTGPKPNSTAAGVSVIA---LDHGFTI-KRSGSLD----YYQQPGMYWIRP
:::::::::::::::::::::::::: ::. . .: . : : ::. :
NP_001 VAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNQDVRSRYKAQPA-----P
670 680 690 700 710
720
pF1KA0 PLLIRRGRFSDEDATRM
: :
NP_001 PELNSESEDYSPSSSETVRSPNSPF
720 730 740
>>XP_016876336 (OMIM: 604742) PREDICTED: serine/threonin (708 aa)
initn: 4605 init1: 4489 opt: 4489 Z-score: 1876.4 bits: 357.8 E(85289): 8.9e-98
Smith-Waterman score: 4566; 96.8% identity (97.0% similar) in 729 aa overlap (1-729:1-708)
10 20 30 40 50 60
pF1KA0 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 VAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGR
:::::::::::::::::::::::::: :. ::::::::::
XP_016 VAGKIKKHFNTGPKPNSTAAGVSVIA-----------------APA----RPPLLIRRGR
670 680 690
pF1KA0 FSDEDATRM
:::::::::
XP_016 FSDEDATRM
700
>>NP_001182344 (OMIM: 604742) serine/threonine-protein k (422 aa)
initn: 2768 init1: 2768 opt: 2768 Z-score: 1170.9 bits: 226.5 E(85289): 1.8e-58
Smith-Waterman score: 2768; 100.0% identity (100.0% similar) in 416 aa overlap (314-729:7-422)
290 300 310 320 330 340
pF1KA0 YTKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRK
::::::::::::::::::::::::::::::
NP_001 MLELIEVNGTPGSQLSTPRSGKSPSPSPTSPGSLRK
10 20 30
350 360 370 380 390 400
pF1KA0 QRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAV
40 50 60 70 80 90
410 420 430 440 450 460
pF1KA0 VKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYL
100 110 120 130 140 150
470 480 490 500 510 520
pF1KA0 VMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQ
160 170 180 190 200 210
530 540 550 560 570 580
pF1KA0 DGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG
220 230 240 250 260 270
590 600 610 620 630 640
pF1KA0 FPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLE
280 290 300 310 320 330
650 660 670 680 690 700
pF1KA0 HPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQ
340 350 360 370 380 390
710 720
pF1KA0 QPGMYWIRPPLLIRRGRFSDEDATRM
::::::::::::::::::::::::::
NP_001 QPGMYWIRPPLLIRRGRFSDEDATRM
400 410 420
>>XP_005262842 (OMIM: 613166) PREDICTED: serine/threonin (782 aa)
initn: 2936 init1: 1483 opt: 2497 Z-score: 1056.5 bits: 206.2 E(85289): 4.1e-52
Smith-Waterman score: 3185; 67.7% identity (83.9% similar) in 746 aa overlap (1-712:1-736)
10 20 30 40
pF1KA0 MSFGRDMELEHFDERDKAQR--------------YSRGSRVNGL-PSPTHSAHCSFYRTR
:. :..:::::.:::: : : : . ::: :::.:::::::::::
XP_005 MASTRSIELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 TLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGV
:::.:::::::::.::::::::::::.:.::: ::::::.::: .:::.:::::::::::
XP_005 TLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 RTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSS
:::::::: .:..:::.:.:::::::.: :::.:..::::.:::::::.: ..:::
XP_005 RTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKG-GTSRA---
130 140 150 160 170
170 180 190 200 210 220
pF1KA0 LATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIK
::.:.. :::.:.::::.:::::.:::::::::::::::::::::::::::::::.:::
XP_005 LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIK
180 190 200 210 220 230
230 240 250 260 270 280
pF1KA0 LDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVKSTSY
::::::::: ::::::: ::::::::::.::::::::::: ::::.::.:::::.:: ::
XP_005 LDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKS-SY
240 250 260 270 280 290
290 300 310 320 330
pF1KA0 TKIASSSRRSTTKSPGPSRRSKSPAST--------------SSVNGTPGSQLSTPRSGKS
.. .:. . : .::::::::::::::. : :::::.::::::.: ::
XP_005 SR-SSAVKYSGSKSPGPSRRSKSPASVKRGGHYSSAYSTAKSPVNGTPSSQLSTPKSTKS
300 310 320 330 340 350
340 350 360 370 380 390
pF1KA0 PSPSPTSPGSLRKQRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERY
: :::::::.: . : :: ::... . .:. .: : :. . . .:. :.:
XP_005 SSSSPTSPGSFRGLKISAHGRSSSNVNGGP---ELDRCISP-EGVNGNRCSESSTLLEKY
360 370 380 390 400 410
400 410 420 430 440 450
pF1KA0 KVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVL
:.:..::::::::::::..:::..:.::::: :.:: ::::.:.::::::::::::::..
XP_005 KIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIM
420 430 440 450 460 470
460 470 480 490 500 510
pF1KA0 LIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHR
:.:::.. :::.:::::::::::::::::..::::::.:.:.::::.:..:::.:.::::
XP_005 LVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHR
480 490 500 510 520 530
520 530 540 550 560 570
pF1KA0 DIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDI
::::::::: :. ::.::::::::::::.:.:::::::::::::::::::::::::::::
XP_005 DIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDI
540 550 560 570 580 590
580 590 600 610 620 630
pF1KA0 WAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLV
::::::::::::::::::. .. :: :::::: :...::.:::::..:::::::..:: :
XP_005 WAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQV
600 610 620 630 640 650
640 650 660 670 680
pF1KA0 DVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTG-PKPNSTAAGVSVI---A
.:. : .: :.: ::::.::. ::. : :.::.:.:::.. :: :::..::::: :
XP_005 NVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTA
660 670 680 690 700 710
690 700 710 720
pF1KA0 LDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGRFSDEDATRM
::. : : . .::: : :
XP_005 LDKEGQIFCSKHCQDSGRPGMEPISPVPPSVEEIPVPGEAVPAPTPPESPTPHPPPAAPG
720 730 740 750 760 770
>>NP_001035350 (OMIM: 613166) serine/threonine-protein k (766 aa)
initn: 2255 init1: 1497 opt: 2485 Z-score: 1051.7 bits: 205.3 E(85289): 7.7e-52
Smith-Waterman score: 3194; 68.8% identity (85.3% similar) in 733 aa overlap (1-712:1-720)
10 20 30 40
pF1KA0 MSFGRDMELEHFDERDKAQR--------------YSRGSRVNGL-PSPTHSAHCSFYRTR
:. :..:::::.:::: : : : . ::: :::.:::::::::::
NP_001 MASTRSIELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 TLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGV
:::.:::::::::.::::::::::::.:.::: ::::::.::: .:::.:::::::::::
NP_001 TLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 RTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSS
:::::::: .:..:::.:.:::::::.: :::.:..::::.:::::::.: ..:::
NP_001 RTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKG-GTSRA---
130 140 150 160 170
170 180 190 200 210 220
pF1KA0 LATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIK
::.:.. :::.:.::::.:::::.:::::::::::::::::::::::::::::::.:::
NP_001 LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIK
180 190 200 210 220 230
230 240 250 260 270 280
pF1KA0 LDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVKSTSY
::::::::: ::::::: ::::::::::.::::::::::: ::::.::.:::::.:: ::
NP_001 LDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKS-SY
240 250 260 270 280 290
290 300 310 320 330 340
pF1KA0 TKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQ
.. .:. . : .:::::::::::::: :::::.::::::.: :: : :::::::.:
NP_001 SR-SSAVKYSGSKSPGPSRRSKSPAS---VNGTPSSQLSTPKSTKSSSSSPTSPGSFRGL
300 310 320 330 340 350
350 360 370 380 390 400
pF1KA0 RS-SQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAV
.. : :: ::... . .:. .: : :. . . .:. :.::.:..::::::::
NP_001 KQISAHGRSSSNVNGGP---ELDRCISP-EGVNGNRCSESSTLLEKYKIGKVIGDGNFAV
360 370 380 390 400
410 420 430 440 450 460
pF1KA0 VKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYL
::::..:::..:.::::: :.:: ::::.:.::::::::::::::..:.:::.. :::.:
NP_001 VKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETATELFL
410 420 430 440 450 460
470 480 490 500 510 520
pF1KA0 VMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQ
::::::::::::::::..::::::.:.:.::::.:..:::.:.::::::::::::: :.
NP_001 VMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYP
470 480 490 500 510 520
530 540 550 560 570 580
pF1KA0 DGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG
::.::::::::::::.:.::::::::::::::::::::::::::::::::::::::::::
NP_001 DGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG
530 540 550 560 570 580
590 600 610 620 630 640
pF1KA0 FPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLE
:::::. .. :: :::::: :...::.:::::..:::::::..:: :.:. : .: :.:
NP_001 FPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILS
590 600 610 620 630 640
650 660 670 680 690
pF1KA0 HPWVNDDGLPENEHQLSVAGKIKKHFNTG-PKPNSTAAGVSVI---ALDHGFTIKRSGSL
::::.::. ::. : :.::.:.:::.. :: :::..::::: :::. : :
NP_001 HPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKHC
650 660 670 680 690 700
700 710 720
pF1KA0 DYYQQPGMYWIRPPLLIRRGRFSDEDATRM
. .::: : :
NP_001 QDSGRPGMEPISPVPPSVEEIPVPGEAVPAPTPPESPTPHPPPAAPGGERAGTWRRHRD
710 720 730 740 750 760
>>NP_001182345 (OMIM: 604742) serine/threonine-protein k (433 aa)
initn: 2462 init1: 2462 opt: 2463 Z-score: 1045.4 bits: 203.3 E(85289): 1.7e-51
Smith-Waterman score: 2463; 93.4% identity (94.6% similar) in 410 aa overlap (314-715:7-411)
290 300 310 320 330 340
pF1KA0 YTKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRK
::::::::::::::::::::::::::::::
NP_001 MLELIEVNGTPGSQLSTPRSGKSPSPSPTSPGSLRK
10 20 30
350 360 370 380 390 400
pF1KA0 QRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAV
40 50 60 70 80 90
410 420 430 440 450 460
pF1KA0 VKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYL
100 110 120 130 140 150
470 480 490 500 510 520
pF1KA0 VMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQ
160 170 180 190 200 210
530 540 550 560 570 580
pF1KA0 DGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG
220 230 240 250 260 270
590 600 610 620 630 640
pF1KA0 FPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLE
280 290 300 310 320 330
650 660 670 680 690
pF1KA0 HPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIA---LDHGFTI-KRSGSL
::::::::::::::::::::::::::::::::::::::::::: ::. . .: .
NP_001 HPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNQ
340 350 360 370 380 390
700 710 720
pF1KA0 D----YYQQPGMYWIRPPLLIRRGRFSDEDATRM
: : ::. :: :
NP_001 DVRSRYKAQPA-----PPELNSESEDYSPSSSETVRSPNSPF
400 410 420 430
>>XP_005262843 (OMIM: 613166) PREDICTED: serine/threonin (765 aa)
initn: 2932 init1: 1483 opt: 2434 Z-score: 1030.7 bits: 201.4 E(85289): 1.1e-50
Smith-Waterman score: 3203; 68.9% identity (85.2% similar) in 732 aa overlap (1-712:1-719)
10 20 30 40
pF1KA0 MSFGRDMELEHFDERDKAQR--------------YSRGSRVNGL-PSPTHSAHCSFYRTR
:. :..:::::.:::: : : : . ::: :::.:::::::::::
XP_005 MASTRSIELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 TLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGV
:::.:::::::::.::::::::::::.:.::: ::::::.::: .:::.:::::::::::
XP_005 TLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 RTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSS
:::::::: .:..:::.:.:::::::.: :::.:..::::.:::::::.: ..:::
XP_005 RTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKG-GTSRA---
130 140 150 160 170
170 180 190 200 210 220
pF1KA0 LATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIK
::.:.. :::.:.::::.:::::.:::::::::::::::::::::::::::::::.:::
XP_005 LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIK
180 190 200 210 220 230
230 240 250 260 270 280
pF1KA0 LDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVKSTSY
::::::::: ::::::: ::::::::::.::::::::::: ::::.::.:::::.:: ::
XP_005 LDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKS-SY
240 250 260 270 280 290
290 300 310 320 330 340
pF1KA0 TKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQ
.. .:. . : .:::::::::::::: :::::.::::::.: :: : :::::::.:
XP_005 SR-SSAVKYSGSKSPGPSRRSKSPAS---VNGTPSSQLSTPKSTKSSSSSPTSPGSFRGL
300 310 320 330 340 350
350 360 370 380 390 400
pF1KA0 RSSQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVV
. : :: ::... . .:. .: : :. . . .:. :.::.:..:::::::::
XP_005 KISAHGRSSSNVNGGP---ELDRCISP-EGVNGNRCSESSTLLEKYKIGKVIGDGNFAVV
360 370 380 390 400
410 420 430 440 450 460
pF1KA0 KECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLV
:::..:::..:.::::: :.:: ::::.:.::::::::::::::..:.:::.. :::.::
XP_005 KECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETATELFLV
410 420 430 440 450 460
470 480 490 500 510 520
pF1KA0 MELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQD
:::::::::::::::..::::::.:.:.::::.:..:::.:.::::::::::::: :. :
XP_005 MELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPD
470 480 490 500 510 520
530 540 550 560 570 580
pF1KA0 GSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGF
:.::::::::::::.:.:::::::::::::::::::::::::::::::::::::::::::
XP_005 GTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGF
530 540 550 560 570 580
590 600 610 620 630 640
pF1KA0 PPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEH
::::. .. :: :::::: :...::.:::::..:::::::..:: :.:. : .: :.: :
XP_005 PPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSH
590 600 610 620 630 640
650 660 670 680 690 700
pF1KA0 PWVNDDGLPENEHQLSVAGKIKKHFNTG-PKPNSTAAGVSVI---ALDHGFTIKRSGSLD
:::.::. ::. : :.::.:.:::.. :: :::..::::: :::. : : .
XP_005 PWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKHCQ
650 660 670 680 690 700
710 720
pF1KA0 YYQQPGMYWIRPPLLIRRGRFSDEDATRM
.::: : :
XP_005 DSGRPGMEPISPVPPSVEEIPVPGEAVPAPTPPESPTPHPPPAAPGGERAGTWRRHRD
710 720 730 740 750 760
>>NP_001035351 (OMIM: 613166) serine/threonine-protein k (783 aa)
initn: 2256 init1: 1498 opt: 2433 Z-score: 1030.2 bits: 201.3 E(85289): 1.2e-50
Smith-Waterman score: 3176; 67.6% identity (83.9% similar) in 747 aa overlap (1-712:1-737)
10 20 30 40
pF1KA0 MSFGRDMELEHFDERDKAQR--------------YSRGSRVNGL-PSPTHSAHCSFYRTR
:. :..:::::.:::: : : : . ::: :::.:::::::::::
NP_001 MASTRSIELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KA0 TLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGV
:::.:::::::::.::::::::::::.:.::: ::::::.::: .:::.:::::::::::
NP_001 TLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KA0 RTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSS
:::::::: .:..:::.:.:::::::.: :::.:..::::.:::::::.: ..:::
NP_001 RTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKG-GTSRA---
130 140 150 160 170
170 180 190 200 210 220
pF1KA0 LATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIK
::.:.. :::.:.::::.:::::.:::::::::::::::::::::::::::::::.:::
NP_001 LAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIK
180 190 200 210 220 230
230 240 250 260 270 280
pF1KA0 LDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVKSTSY
::::::::: ::::::: ::::::::::.::::::::::: ::::.::.:::::.:: ::
NP_001 LDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKS-SY
240 250 260 270 280 290
290 300 310 320 330
pF1KA0 TKIASSSRRSTTKSPGPSRRSKSPAST--------------SSVNGTPGSQLSTPRSGKS
.. .:. . : .::::::::::::::. : :::::.::::::.: ::
NP_001 SR-SSAVKYSGSKSPGPSRRSKSPASVKRGGHYSSAYSTAKSPVNGTPSSQLSTPKSTKS
300 310 320 330 340 350
340 350 360 370 380
pF1KA0 PSPSPTSPGSLRKQRS-SQHGGSSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITER
: :::::::.: .. : :: ::... . .:. .: : :. . . .:. :.
NP_001 SSSSPTSPGSFRGLKQISAHGRSSSNVNGGP---ELDRCISP-EGVNGNRCSESSTLLEK
360 370 380 390 400 410
390 400 410 420 430 440
pF1KA0 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIV
::.:..::::::::::::..:::..:.::::: :.:: ::::.:.::::::::::::::.
NP_001 YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNII
420 430 440 450 460 470
450 460 470 480 490 500
pF1KA0 LLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVH
.:.:::.. :::.:::::::::::::::::..::::::.:.:.::::.:..:::.:.:::
NP_001 MLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVH
480 490 500 510 520 530
510 520 530 540 550 560
pF1KA0 RDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVD
:::::::::: :. ::.::::::::::::.:.::::::::::::::::::::::::::::
NP_001 RDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVD
540 550 560 570 580 590
570 580 590 600 610 620
pF1KA0 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLL
:::::::::::::::::::. .. :: :::::: :...::.:::::..:::::::..::
NP_001 IWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQ
600 610 620 630 640 650
630 640 650 660 670 680
pF1KA0 VDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTG-PKPNSTAAGVSVI---
:.:. : .: :.: ::::.::. ::. : :.::.:.:::.. :: :::..:::::
NP_001 VNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNT
660 670 680 690 700 710
690 700 710 720
pF1KA0 ALDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGRFSDEDATRM
:::. : : . .::: : :
NP_001 ALDKEGQIFCSKHCQDSGRPGMEPISPVPPSVEEIPVPGEAVPAPTPPESPTPHPPPAAP
720 730 740 750 760 770
729 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 18:44:42 2016 done: Wed Nov 2 18:44:44 2016
Total Scan time: 12.430 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]