Result of FASTA (omim) for
pFN21AE9666
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9666, 1186 aa
1>>>pF1KE9666 1186 - 1186 aa - 1186 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4265+/-0.000413; mu= 8.1547+/- 0.026
mean_var=164.5943+/-34.219, 0's: 0 Z-trim(116.4): 21 B-trim: 413 in 1/51
Lambda= 0.099969
statistics sampled from 27461 (27479) to 27461 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.322), width: 16
Scan time: 18.160
The best scores are: opt bits E(85289)
NP_000114 (OMIM: 133530,278780,616570) DNA repair (1186) 7706 1124.5 0
XP_005262670 (OMIM: 612449) PREDICTED: flap endonu ( 908) 325 59.9 8.4e-08
XP_011531124 (OMIM: 612449) PREDICTED: flap endonu ( 908) 325 59.9 8.4e-08
XP_006712068 (OMIM: 612449) PREDICTED: flap endonu ( 908) 325 59.9 8.4e-08
XP_011531123 (OMIM: 612449) PREDICTED: flap endonu ( 908) 325 59.9 8.4e-08
XP_011531122 (OMIM: 612449) PREDICTED: flap endonu ( 908) 325 59.9 8.4e-08
NP_001123481 (OMIM: 612449) flap endonuclease GEN ( 908) 325 59.9 8.4e-08
NP_872431 (OMIM: 612449) flap endonuclease GEN hom ( 908) 325 59.9 8.4e-08
NP_004102 (OMIM: 600393) flap endonuclease 1 [Homo ( 380) 242 47.8 0.00016
>>NP_000114 (OMIM: 133530,278780,616570) DNA repair prot (1186 aa)
initn: 7706 init1: 7706 opt: 7706 Z-score: 6012.5 bits: 1124.5 E(85289): 0
Smith-Waterman score: 7706; 100.0% identity (100.0% similar) in 1186 aa overlap (1-1186:1-1186)
10 20 30 40 50 60
pF1KE9 MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 RLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TAFRSKRDEALPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TAFRSKRDEALPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 NYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 AEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 LESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 INSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 INSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 VGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 EVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 ENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 ISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 AEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 IPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDF
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 HNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 KNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIRE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 FCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVT
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 CMLRKEKEAAASEIEAVSVAMEKEFELLDKAKRKTQKRGITNTLEESSSLKRKRLSDSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CMLRKEKEAAASEIEAVSVAMEKEFELLDKAKRKTQKRGITNTLEESSSLKRKRLSDSKR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 KNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKN
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180
pF1KE9 GGATTSSSSDSDDDGGKEKMVLVTARSVFGKKRRKLRRARGRKRKT
::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GGATTSSSSDSDDDGGKEKMVLVTARSVFGKKRRKLRRARGRKRKT
1150 1160 1170 1180
>>XP_005262670 (OMIM: 612449) PREDICTED: flap endonuclea (908 aa)
initn: 399 init1: 179 opt: 325 Z-score: 261.1 bits: 59.9 E(85289): 8.4e-08
Smith-Waterman score: 325; 32.8% identity (67.7% similar) in 198 aa overlap (739-928:81-270)
710 720 730 740 750 760
pF1KE9 DVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLK---AQKQQQERIAATVT
:........:. . . :. ... . .
XP_005 PHLRNLFFRISYLTQMDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGKSWSQKTGRSHF
60 70 80 90 100 110
770 780 790 800 810 820
pF1KE9 GQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNF
... : ..:. .:::..:: ::::.:: :. ...: .:.:.: .:.::. :::::
XP_005 KSVLRECLHMLECLGIPWVQAAGEAEAMCAYLNAGGHVDGCLTNDGDTFLYGAQTVYRNF
120 130 140 150 160 170
830 840 850 860 870 880
pF1KE9 F--NKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYT-EGIPTVGCVTAMEILNEFP
.:. :. : . .....:::::. :..:: ::: :: .:.: :: :..... .
XP_005 TMNTKDPHVDCYTMSSIKSKLGLDRDALVGLAILLGCDYLPKGVPGVGKEQALKLIQILK
180 190 200 210 220 230
890 900 910 920 930 940
pF1KE9 GHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLT--PGFPNPAVAEAYLKPV
:..: : .:..: .:.. : .:. : ::: .. :: :
XP_005 GQSL--LQRFNRW-NETSCNS----SPQ-LLVTKKLAHCSVCSHPGSPKDHERNGCRLCK
240 250 260 270 280
950 960 970 980 990 1000
pF1KE9 VDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLA
XP_005 SDKYCEPHDYEYCCPCEWHRTEHDRQLSEVENNIKKKACCCEGFPFHEVIQEFLLNKDKL
290 300 310 320 330 340
>>XP_011531124 (OMIM: 612449) PREDICTED: flap endonuclea (908 aa)
initn: 399 init1: 179 opt: 325 Z-score: 261.1 bits: 59.9 E(85289): 8.4e-08
Smith-Waterman score: 325; 32.8% identity (67.7% similar) in 198 aa overlap (739-928:81-270)
710 720 730 740 750 760
pF1KE9 DVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLK---AQKQQQERIAATVT
:........:. . . :. ... . .
XP_011 PHLRNLFFRISYLTQMDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGKSWSQKTGRSHF
60 70 80 90 100 110
770 780 790 800 810 820
pF1KE9 GQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNF
... : ..:. .:::..:: ::::.:: :. ...: .:.:.: .:.::. :::::
XP_011 KSVLRECLHMLECLGIPWVQAAGEAEAMCAYLNAGGHVDGCLTNDGDTFLYGAQTVYRNF
120 130 140 150 160 170
830 840 850 860 870 880
pF1KE9 F--NKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYT-EGIPTVGCVTAMEILNEFP
.:. :. : . .....:::::. :..:: ::: :: .:.: :: :..... .
XP_011 TMNTKDPHVDCYTMSSIKSKLGLDRDALVGLAILLGCDYLPKGVPGVGKEQALKLIQILK
180 190 200 210 220 230
890 900 910 920 930 940
pF1KE9 GHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLT--PGFPNPAVAEAYLKPV
:..: : .:..: .:.. : .:. : ::: .. :: :
XP_011 GQSL--LQRFNRW-NETSCNS----SPQ-LLVTKKLAHCSVCSHPGSPKDHERNGCRLCK
240 250 260 270 280
950 960 970 980 990 1000
pF1KE9 VDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLA
XP_011 SDKYCEPHDYEYCCPCEWHRTEHDRQLSEVENNIKKKACCCEGFPFHEVIQEFLLNKDKL
290 300 310 320 330 340
>>XP_006712068 (OMIM: 612449) PREDICTED: flap endonuclea (908 aa)
initn: 399 init1: 179 opt: 325 Z-score: 261.1 bits: 59.9 E(85289): 8.4e-08
Smith-Waterman score: 325; 32.8% identity (67.7% similar) in 198 aa overlap (739-928:81-270)
710 720 730 740 750 760
pF1KE9 DVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLK---AQKQQQERIAATVT
:........:. . . :. ... . .
XP_006 PHLRNLFFRISYLTQMDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGKSWSQKTGRSHF
60 70 80 90 100 110
770 780 790 800 810 820
pF1KE9 GQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNF
... : ..:. .:::..:: ::::.:: :. ...: .:.:.: .:.::. :::::
XP_006 KSVLRECLHMLECLGIPWVQAAGEAEAMCAYLNAGGHVDGCLTNDGDTFLYGAQTVYRNF
120 130 140 150 160 170
830 840 850 860 870 880
pF1KE9 F--NKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYT-EGIPTVGCVTAMEILNEFP
.:. :. : . .....:::::. :..:: ::: :: .:.: :: :..... .
XP_006 TMNTKDPHVDCYTMSSIKSKLGLDRDALVGLAILLGCDYLPKGVPGVGKEQALKLIQILK
180 190 200 210 220 230
890 900 910 920 930 940
pF1KE9 GHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLT--PGFPNPAVAEAYLKPV
:..: : .:..: .:.. : .:. : ::: .. :: :
XP_006 GQSL--LQRFNRW-NETSCNS----SPQ-LLVTKKLAHCSVCSHPGSPKDHERNGCRLCK
240 250 260 270 280
950 960 970 980 990 1000
pF1KE9 VDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLA
XP_006 SDKYCEPHDYEYCCPCEWHRTEHDRQLSEVENNIKKKACCCEGFPFHEVIQEFLLNKDKL
290 300 310 320 330 340
>>XP_011531123 (OMIM: 612449) PREDICTED: flap endonuclea (908 aa)
initn: 399 init1: 179 opt: 325 Z-score: 261.1 bits: 59.9 E(85289): 8.4e-08
Smith-Waterman score: 325; 32.8% identity (67.7% similar) in 198 aa overlap (739-928:81-270)
710 720 730 740 750 760
pF1KE9 DVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLK---AQKQQQERIAATVT
:........:. . . :. ... . .
XP_011 PHLRNLFFRISYLTQMDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGKSWSQKTGRSHF
60 70 80 90 100 110
770 780 790 800 810 820
pF1KE9 GQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNF
... : ..:. .:::..:: ::::.:: :. ...: .:.:.: .:.::. :::::
XP_011 KSVLRECLHMLECLGIPWVQAAGEAEAMCAYLNAGGHVDGCLTNDGDTFLYGAQTVYRNF
120 130 140 150 160 170
830 840 850 860 870 880
pF1KE9 F--NKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYT-EGIPTVGCVTAMEILNEFP
.:. :. : . .....:::::. :..:: ::: :: .:.: :: :..... .
XP_011 TMNTKDPHVDCYTMSSIKSKLGLDRDALVGLAILLGCDYLPKGVPGVGKEQALKLIQILK
180 190 200 210 220 230
890 900 910 920 930 940
pF1KE9 GHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLT--PGFPNPAVAEAYLKPV
:..: : .:..: .:.. : .:. : ::: .. :: :
XP_011 GQSL--LQRFNRW-NETSCNS----SPQ-LLVTKKLAHCSVCSHPGSPKDHERNGCRLCK
240 250 260 270 280
950 960 970 980 990 1000
pF1KE9 VDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLA
XP_011 SDKYCEPHDYEYCCPCEWHRTEHDRQLSEVENNIKKKACCCEGFPFHEVIQEFLLNKDKL
290 300 310 320 330 340
>>XP_011531122 (OMIM: 612449) PREDICTED: flap endonuclea (908 aa)
initn: 399 init1: 179 opt: 325 Z-score: 261.1 bits: 59.9 E(85289): 8.4e-08
Smith-Waterman score: 325; 32.8% identity (67.7% similar) in 198 aa overlap (739-928:81-270)
710 720 730 740 750 760
pF1KE9 DVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLK---AQKQQQERIAATVT
:........:. . . :. ... . .
XP_011 PHLRNLFFRISYLTQMDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGKSWSQKTGRSHF
60 70 80 90 100 110
770 780 790 800 810 820
pF1KE9 GQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNF
... : ..:. .:::..:: ::::.:: :. ...: .:.:.: .:.::. :::::
XP_011 KSVLRECLHMLECLGIPWVQAAGEAEAMCAYLNAGGHVDGCLTNDGDTFLYGAQTVYRNF
120 130 140 150 160 170
830 840 850 860 870 880
pF1KE9 F--NKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYT-EGIPTVGCVTAMEILNEFP
.:. :. : . .....:::::. :..:: ::: :: .:.: :: :..... .
XP_011 TMNTKDPHVDCYTMSSIKSKLGLDRDALVGLAILLGCDYLPKGVPGVGKEQALKLIQILK
180 190 200 210 220 230
890 900 910 920 930 940
pF1KE9 GHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLT--PGFPNPAVAEAYLKPV
:..: : .:..: .:.. : .:. : ::: .. :: :
XP_011 GQSL--LQRFNRW-NETSCNS----SPQ-LLVTKKLAHCSVCSHPGSPKDHERNGCRLCK
240 250 260 270 280
950 960 970 980 990 1000
pF1KE9 VDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLA
XP_011 SDKYCEPHDYEYCCPCEWHRTEHDRQLSEVENNIKKKACCCEGFPFHEVIQEFLLNKDKL
290 300 310 320 330 340
>>NP_001123481 (OMIM: 612449) flap endonuclease GEN homo (908 aa)
initn: 399 init1: 179 opt: 325 Z-score: 261.1 bits: 59.9 E(85289): 8.4e-08
Smith-Waterman score: 325; 32.8% identity (67.7% similar) in 198 aa overlap (739-928:81-270)
710 720 730 740 750 760
pF1KE9 DVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLK---AQKQQQERIAATVT
:........:. . . :. ... . .
NP_001 PHLRNLFFRISYLTQMDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGKSWSQKTGRSHF
60 70 80 90 100 110
770 780 790 800 810 820
pF1KE9 GQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNF
... : ..:. .:::..:: ::::.:: :. ...: .:.:.: .:.::. :::::
NP_001 KSVLRECLHMLECLGIPWVQAAGEAEAMCAYLNAGGHVDGCLTNDGDTFLYGAQTVYRNF
120 130 140 150 160 170
830 840 850 860 870 880
pF1KE9 F--NKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYT-EGIPTVGCVTAMEILNEFP
.:. :. : . .....:::::. :..:: ::: :: .:.: :: :..... .
NP_001 TMNTKDPHVDCYTMSSIKSKLGLDRDALVGLAILLGCDYLPKGVPGVGKEQALKLIQILK
180 190 200 210 220 230
890 900 910 920 930 940
pF1KE9 GHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLT--PGFPNPAVAEAYLKPV
:..: : .:..: .:.. : .:. : ::: .. :: :
NP_001 GQSL--LQRFNRW-NETSCNS----SPQ-LLVTKKLAHCSVCSHPGSPKDHERNGCRLCK
240 250 260 270 280
950 960 970 980 990 1000
pF1KE9 VDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLA
NP_001 SDKYCEPHDYEYCCPCEWHRTEHDRQLNEVENNIKKKACCCEGFPFHEVIQEFLLNKDKL
290 300 310 320 330 340
>>NP_872431 (OMIM: 612449) flap endonuclease GEN homolog (908 aa)
initn: 399 init1: 179 opt: 325 Z-score: 261.1 bits: 59.9 E(85289): 8.4e-08
Smith-Waterman score: 325; 32.8% identity (67.7% similar) in 198 aa overlap (739-928:81-270)
710 720 730 740 750 760
pF1KE9 DVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLK---AQKQQQERIAATVT
:........:. . . :. ... . .
NP_872 PHLRNLFFRISYLTQMDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGKSWSQKTGRSHF
60 70 80 90 100 110
770 780 790 800 810 820
pF1KE9 GQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNF
... : ..:. .:::..:: ::::.:: :. ...: .:.:.: .:.::. :::::
NP_872 KSVLRECLHMLECLGIPWVQAAGEAEAMCAYLNAGGHVDGCLTNDGDTFLYGAQTVYRNF
120 130 140 150 160 170
830 840 850 860 870 880
pF1KE9 F--NKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYT-EGIPTVGCVTAMEILNEFP
.:. :. : . .....:::::. :..:: ::: :: .:.: :: :..... .
NP_872 TMNTKDPHVDCYTMSSIKSKLGLDRDALVGLAILLGCDYLPKGVPGVGKEQALKLIQILK
180 190 200 210 220 230
890 900 910 920 930 940
pF1KE9 GHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLT--PGFPNPAVAEAYLKPV
:..: : .:..: .:.. : .:. : ::: .. :: :
NP_872 GQSL--LQRFNRW-NETSCNS----SPQ-LLVTKKLAHCSVCSHPGSPKDHERNGCRLCK
240 250 260 270 280
950 960 970 980 990 1000
pF1KE9 VDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLA
NP_872 SDKYCEPHDYEYCCPCEWHRTEHDRQLNEVENNIKKKACCCEGFPFHEVIQEFLLNKDKL
290 300 310 320 330 340
>>NP_004102 (OMIM: 600393) flap endonuclease 1 [Homo sap (380 aa)
initn: 388 init1: 143 opt: 242 Z-score: 202.1 bits: 47.8 E(85289): 0.00016
Smith-Waterman score: 272; 26.8% identity (59.9% similar) in 272 aa overlap (746-1009:112-355)
720 730 740 750 760 770
pF1KE9 EAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIA---ATVTGQMFLES
:: . . .:. :... . :: : :
NP_004 VYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDEC
90 100 110 120 130 140
780 790 800 810 820
pF1KE9 QELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFN---KN
..:: :.::::..:: ::::.:: : . .. .. :.: : ::. ..:.. :.
NP_004 KHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKK
150 160 170 180 190 200
830 840 850 860 870 880
pF1KE9 KFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPL
.. .. . ..:::.......: :::::: :.: .: :...... ...: .
NP_004 LPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKH--KSIEEI
210 220 230 240 250
890 900 910 920 930 940
pF1KE9 LKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFL
.. . .:. : :.. ..:. . : : : .: .: ::
NP_004 VR--------RLDPNKYPVPENW-LHKEAHQLFLEPEVLDPESVE--LK-----------
260 270 280 290
950 960 970 980 990 1000
pF1KE9 WGKPDLDKIREF-C-QRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDA
:..:. ... .: : .. :. .: .. . . .: .:: :.:.::... . . .:
NP_004 WSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQ---GSTQGRLDDFFKVTGSLS-SA
300 310 320 330 340 350
1010 1020 1030 1040 1050 1060
pF1KE9 KRIKSQRLNRAVTCMLRKEKEAAASEIEAVSVAMEKEFELLDKAKRKTQKRGITNTLEES
::
NP_004 KRKEPEPKGSTKKKAKTGAAGKFKRGK
360 370 380
1186 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:10:01 2016 done: Mon Nov 7 00:10:04 2016
Total Scan time: 18.160 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]