Result of FASTA (ccds) for
pFN21AE9661
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9661, 255 aa
1>>>pF1KE9661 255 - 255 aa - 255 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8488+/-0.000847; mu= 12.2662+/- 0.051
mean_var=75.6679+/-15.037, 0's: 0 Z-trim(107.1): 24 B-trim: 0 in 0/49
Lambda= 0.147441
statistics sampled from 9360 (9383) to 9360 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.288), width: 16
Scan time: 2.260
The best scores are: opt bits E(32554)
CCDS43056.1 METTL6 gene_id:131965|Hs108|chr3 ( 284) 1719 374.8 3.6e-104
CCDS77706.1 METTL6 gene_id:131965|Hs108|chr3 ( 239) 906 201.8 3.5e-52
CCDS5803.2 METTL2B gene_id:55798|Hs108|chr7 ( 378) 560 128.3 7.4e-30
CCDS45752.1 METTL2A gene_id:339175|Hs108|chr17 ( 378) 555 127.2 1.6e-29
CCDS2242.2 METTL8 gene_id:79828|Hs108|chr2 ( 407) 504 116.4 3.1e-26
CCDS82531.1 METTL8 gene_id:79828|Hs108|chr2 ( 241) 259 64.2 9.5e-11
>>CCDS43056.1 METTL6 gene_id:131965|Hs108|chr3 (284 aa)
initn: 1719 init1: 1719 opt: 1719 Z-score: 1983.8 bits: 374.8 E(32554): 3.6e-104
Smith-Waterman score: 1719; 100.0% identity (100.0% similar) in 255 aa overlap (1-255:1-255)
10 20 30 40 50 60
pF1KE9 MASLQRKGLQARILTSEEEEKLKRDQTLVSDFKQQKLEQEAQKNWDLFYKRNSTNFFKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MASLQRKGLQARILTSEEEEKLKRDQTLVSDFKQQKLEQEAQKNWDLFYKRNSTNFFKDR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 HWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLLEEDPNIFAYACDFSPRAIEYVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 HWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLLEEDPNIFAYACDFSPRAIEYVK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 QNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 QNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 PGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 PGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVV
190 200 210 220 230 240
250
pF1KE9 NEYVFRETVNKKEGL
:::::::::::::::
CCDS43 NEYVFRETVNKKEGLCVPRVFLQSKFLKPPKNPSPVVLGLDPKS
250 260 270 280
>>CCDS77706.1 METTL6 gene_id:131965|Hs108|chr3 (239 aa)
initn: 906 init1: 906 opt: 906 Z-score: 1050.3 bits: 201.8 E(32554): 3.5e-52
Smith-Waterman score: 1302; 82.4% identity (82.4% similar) in 255 aa overlap (1-255:1-210)
10 20 30 40 50 60
pF1KE9 MASLQRKGLQARILTSEEEEKLKRDQTLVSDFKQQKLEQEAQKNWDLFYKRNSTNFFKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 MASLQRKGLQARILTSEEEEKLKRDQTLVSDFKQQKLEQEAQKNWDLFYKRNSTNFFKDR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 HWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLLEEDPNIFAYACDFSPRAIEYVK
:::::::::::::::
CCDS77 HWTTREFEELRSCRE---------------------------------------------
70
130 140 150 160 170 180
pF1KE9 QNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 QNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLK
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE9 PGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVV
140 150 160 170 180 190
250
pF1KE9 NEYVFRETVNKKEGL
:::::::::::::::
CCDS77 NEYVFRETVNKKEGLCVPRVFLQSKFLKPPKNPSPVVLGLDPKS
200 210 220 230
>>CCDS5803.2 METTL2B gene_id:55798|Hs108|chr7 (378 aa)
initn: 670 init1: 475 opt: 560 Z-score: 649.5 bits: 128.3 E(32554): 7.4e-30
Smith-Waterman score: 560; 48.2% identity (69.5% similar) in 197 aa overlap (64-255:162-358)
40 50 60 70 80 90
pF1KE9 QQKLEQEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRSCR-EFEDQKLT--MLEAGCGV
:... .:. : :: .. : .::.::::
CCDS58 GPGLIMEEQHKCSSKSLEHKTQTPPVEENVTQKISDLEICADEFPGSSATYRILEVGCGV
140 150 160 170 180 190
100 110 120 130 140
pF1KE9 GNCLFPLLE--EDPNIFAYACDFSPRAIEYVKQNPLYDTERCKVFQCDLTKDDLLDHVPP
:: .::.:. .::..:.: :::: ::: :. : :: :: .: :: .. ::
CCDS58 GNTVFPILQTNNDPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEEKSYPVPK
200 210 220 230 240 250
150 160 170 180 190 200
pF1KE9 ESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKASSKLGE
:.:...:::::::: ::::. ... . ..:::: ::.:::: :: :.:::: .. :.
CCDS58 GSLDIIILIFVLSAVVPDKMQKAINRLSRLLKPGGMVLLRDYGRYDMAQLRFKKGQCLSG
260 270 280 290 300 310
210 220 230 240 250
pF1KE9 NFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVVNEYVFRETVNKKEGL
::::: :::: ::::.. : :: .: :.: : : ::. . :
CCDS58 NFYVRGDGTRVYFFTQEELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYCK
320 330 340 350 360 370
CCDS58 PLLSSTS
>>CCDS45752.1 METTL2A gene_id:339175|Hs108|chr17 (378 aa)
initn: 665 init1: 470 opt: 555 Z-score: 643.7 bits: 127.2 E(32554): 1.6e-29
Smith-Waterman score: 555; 47.2% identity (69.5% similar) in 197 aa overlap (64-255:162-358)
40 50 60 70 80 90
pF1KE9 QQKLEQEAQKNWDLFYKRNSTNFFKDRHWTTREFEELRSCR-EFEDQKLT--MLEAGCGV
:... .:. : :: .. : .::.::::
CCDS45 GPGLIMEEQHKCSSKSLEHKTQTLPVEENVTQKISDLEICADEFPGSSATYRILEVGCGV
140 150 160 170 180 190
100 110 120 130 140
pF1KE9 GNCLFPLLE--EDPNIFAYACDFSPRAIEYVKQNPLYDTERCKVFQCDLTKDDLLDHVPP
:: .::.:. .::..:.: :::: ::: :. : :: :: .: :: .. ::
CCDS45 GNTVFPILQTNNDPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEEKSYPVPK
200 210 220 230 240 250
150 160 170 180 190 200
pF1KE9 ESVDVVMLIFVLSAVHPDKMHLVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKASSKLGE
:.:...:::::::. ::::. ... . ..:::: .:.:::: :: :.:::: .. :.
CCDS45 GSLDIIILIFVLSAIVPDKMQKAINRLSRLLKPGGMMLLRDYGRYDMAQLRFKKGQCLSG
260 270 280 290 300 310
210 220 230 240 250
pF1KE9 NFYVRQDGTRSYFFTDDFLAQLFMDTGYEEVVNEYVFRETVNKKEGL
::::: :::: ::::.. : :: .: :.: : : ::. . :
CCDS45 NFYVRGDGTRVYFFTQEELDTLFTTAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYCK
320 330 340 350 360 370
CCDS45 PLLSSTS
>>CCDS2242.2 METTL8 gene_id:79828|Hs108|chr2 (407 aa)
initn: 630 init1: 443 opt: 504 Z-score: 584.6 bits: 116.4 E(32554): 3.1e-26
Smith-Waterman score: 504; 45.4% identity (70.1% similar) in 174 aa overlap (83-253:200-373)
60 70 80 90 100
pF1KE9 STNFFKDRHWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLL---EEDPNIFAYAC
.::.:::.:: .::.: :..:. : : :
CCDS22 ESDFSNLDSEKHKKGPMETGLFPGSNATFRILEVGCGAGNSVFPILNTLENSPESFLYCC
170 180 190 200 210 220
110 120 130 140 150 160
pF1KE9 DFSPRAIEYVKQNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMH
::. :.: ::.. : . .: .: :. : : : .::..:.::::..:::.:.
CCDS22 DFASGAVELVKSHSSYRATQCFAFVHDVCDDGLPYPFPDGILDVILLVFVLSSIHPDRMQ
230 240 250 260 270 280
170 180 190 200 210 220
pF1KE9 LVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQ
:.. . :.:::: .:::::: ::...:::: . :.:::::: ::::.:::: . .
CCDS22 GVVNRLSKLLKPGGMLLFRDYGRYDKTQLRFKKGHCLSENFYVRGDGTRAYFFTKGEVHS
290 300 310 320 330 340
230 240 250
pF1KE9 LFMDTGYEEVVNEYVFRETVNKKEGL
.: .. .: : : ::.:.
CCDS22 MFCKASLDEKQNLVDRRLQVNRKKQVKMHRVWIQGKFQKPLHQTQNSSNMVSTLLSQD
350 360 370 380 390 400
>>CCDS82531.1 METTL8 gene_id:79828|Hs108|chr2 (241 aa)
initn: 385 init1: 198 opt: 259 Z-score: 306.5 bits: 64.2 E(32554): 9.5e-11
Smith-Waterman score: 259; 41.3% identity (68.5% similar) in 92 aa overlap (83-171:150-241)
60 70 80 90 100
pF1KE9 STNFFKDRHWTTREFEELRSCREFEDQKLTMLEAGCGVGNCLFPLL---EEDPNIFAYAC
.::.:::.:: .::.: :..:. : : :
CCDS82 ESDFSNLDSEKHKKGPMETGLFPGSNATFRILEVGCGAGNSVFPILNTLENSPESFLYCC
120 130 140 150 160 170
110 120 130 140 150 160
pF1KE9 DFSPRAIEYVKQNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLSAVHPDKMH
::. :.: ::.. : . .: .: :. : : : .::..:.::::..:::.
CCDS82 DFASGAVELVKSHSSYRATQCFAFVHDVCDDGLPYPFPDGILDVILLVFVLSSIHPDRTL
180 190 200 210 220 230
170 180 190 200 210 220
pF1KE9 LVLQNIYKVLKPGKSVLFRDYGLYDHAMLRFKASSKLGENFYVRQDGTRSYFFTDDFLAQ
..
CCDS82 FI
240
255 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:45:12 2016 done: Mon Nov 7 17:45:12 2016
Total Scan time: 2.260 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]