Result of FASTA (omim) for
pFN21AE9641
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9641, 396 aa
1>>>pF1KE9641 396 - 396 aa - 396 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1058+/-0.000444; mu= -3.5217+/- 0.028
mean_var=291.2784+/-60.536, 0's: 0 Z-trim(118.9): 30 B-trim: 491 in 1/54
Lambda= 0.075148
statistics sampled from 32324 (32354) to 32324 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.379), width: 16
Scan time: 7.150
The best scores are: opt bits E(85289)
NP_004897 (OMIM: 605442) pre-mRNA-splicing regulat ( 396) 2533 287.9 2.8e-77
NP_001257460 (OMIM: 605442) pre-mRNA-splicing regu ( 396) 2533 287.9 2.8e-77
XP_016867003 (OMIM: 605442) PREDICTED: pre-mRNA-sp ( 413) 2533 288.0 2.9e-77
XP_016867004 (OMIM: 605442) PREDICTED: pre-mRNA-sp ( 369) 2360 269.2 1.2e-71
NP_690596 (OMIM: 605442) pre-mRNA-splicing regulat ( 151) 963 117.4 2.3e-26
NP_690597 (OMIM: 605442) pre-mRNA-splicing regulat ( 151) 963 117.4 2.3e-26
NP_001257461 (OMIM: 605442) pre-mRNA-splicing regu ( 170) 963 117.4 2.6e-26
NP_001257462 (OMIM: 605442) pre-mRNA-splicing regu ( 170) 963 117.4 2.6e-26
XP_016867005 (OMIM: 605442) PREDICTED: pre-mRNA-sp ( 187) 963 117.5 2.8e-26
>>NP_004897 (OMIM: 605442) pre-mRNA-splicing regulator W (396 aa)
initn: 2533 init1: 2533 opt: 2533 Z-score: 1508.4 bits: 287.9 E(85289): 2.8e-77
Smith-Waterman score: 2533; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396)
10 20 30 40 50 60
pF1KE9 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 AQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 QQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 DDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSH
310 320 330 340 350 360
370 380 390
pF1KE9 DPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGSVL
::::::::::::::::::::::::::::::::::::
NP_004 DPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGSVL
370 380 390
>>NP_001257460 (OMIM: 605442) pre-mRNA-splicing regulato (396 aa)
initn: 2533 init1: 2533 opt: 2533 Z-score: 1508.4 bits: 287.9 E(85289): 2.8e-77
Smith-Waterman score: 2533; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396)
10 20 30 40 50 60
pF1KE9 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 AQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 QQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 DDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSH
310 320 330 340 350 360
370 380 390
pF1KE9 DPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGSVL
::::::::::::::::::::::::::::::::::::
NP_001 DPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGSVL
370 380 390
>>XP_016867003 (OMIM: 605442) PREDICTED: pre-mRNA-splici (413 aa)
initn: 2533 init1: 2533 opt: 2533 Z-score: 1508.1 bits: 288.0 E(85289): 2.9e-77
Smith-Waterman score: 2533; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:18-413)
10 20 30 40
pF1KE9 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGK
:::::::::::::::::::::::::::::::::::::::::::
XP_016 MRGKASVSKFSKLTGFKMTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 YTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 SVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRM
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 LIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTIL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 VLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSS
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE9 RQRTSGSGFHREGNTTEDDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQRTSGSGFHREGNTTEDDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPT
310 320 330 340 350 360
350 360 370 380 390
pF1KE9 GSENSLTHQSNDTDSSHDPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGSVL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSENSLTHQSNDTDSSHDPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGSVL
370 380 390 400 410
>>XP_016867004 (OMIM: 605442) PREDICTED: pre-mRNA-splici (369 aa)
initn: 2360 init1: 2360 opt: 2360 Z-score: 1407.4 bits: 269.2 E(85289): 1.2e-71
Smith-Waterman score: 2360; 99.7% identity (100.0% similar) in 369 aa overlap (28-396:1-369)
10 20 30 40 50 60
pF1KE9 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
.::::::::::::::::::::::::::::::::
XP_016 MRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
10 20 30
70 80 90 100 110 120
pF1KE9 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE9 FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE9 AQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE9 QQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE9 DDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSH
280 290 300 310 320 330
370 380 390
pF1KE9 DPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGSVL
::::::::::::::::::::::::::::::::::::
XP_016 DPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGSVL
340 350 360
>>NP_690596 (OMIM: 605442) pre-mRNA-splicing regulator W (151 aa)
initn: 963 init1: 963 opt: 963 Z-score: 594.2 bits: 117.4 E(85289): 2.3e-26
Smith-Waterman score: 963; 100.0% identity (100.0% similar) in 150 aa overlap (1-150:1-150)
10 20 30 40 50 60
pF1KE9 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI
::::::::::::::::::::::::::::::
NP_690 FLKMKGELEQTKDKLEQAQNELSAWKFTPDR
130 140 150
>>NP_690597 (OMIM: 605442) pre-mRNA-splicing regulator W (151 aa)
initn: 963 init1: 963 opt: 963 Z-score: 594.2 bits: 117.4 E(85289): 2.3e-26
Smith-Waterman score: 963; 100.0% identity (100.0% similar) in 150 aa overlap (1-150:1-150)
10 20 30 40 50 60
pF1KE9 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI
::::::::::::::::::::::::::::::
NP_690 FLKMKGELEQTKDKLEQAQNELSAWKFTPDR
130 140 150
>>NP_001257461 (OMIM: 605442) pre-mRNA-splicing regulato (170 aa)
initn: 983 init1: 963 opt: 963 Z-score: 593.5 bits: 117.4 E(85289): 2.6e-26
Smith-Waterman score: 963; 100.0% identity (100.0% similar) in 150 aa overlap (1-150:1-150)
10 20 30 40 50 60
pF1KE9 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI
::::::::::::::::::::::::::::::
NP_001 FLKMKGELEQTKDKLEQAQNELSAWKFTPDRGLMASDYSEEVATSEKFPF
130 140 150 160 170
>>NP_001257462 (OMIM: 605442) pre-mRNA-splicing regulato (170 aa)
initn: 983 init1: 963 opt: 963 Z-score: 593.5 bits: 117.4 E(85289): 2.6e-26
Smith-Waterman score: 963; 100.0% identity (100.0% similar) in 150 aa overlap (1-150:1-150)
10 20 30 40 50 60
pF1KE9 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI
::::::::::::::::::::::::::::::
NP_001 FLKMKGELEQTKDKLEQAQNELSAWKFTPDRGLMASDYSEEVATSEKFPF
130 140 150 160 170
>>XP_016867005 (OMIM: 605442) PREDICTED: pre-mRNA-splici (187 aa)
initn: 983 init1: 963 opt: 963 Z-score: 592.9 bits: 117.5 E(85289): 2.8e-26
Smith-Waterman score: 963; 100.0% identity (100.0% similar) in 150 aa overlap (1-150:18-167)
10 20 30 40
pF1KE9 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGK
:::::::::::::::::::::::::::::::::::::::::::
XP_016 MRGKASVSKFSKLTGFKMTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 YTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 SVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRM
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDRGLMASDYSEEVA
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 LIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTIL
XP_016 TSEKFPF
396 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 06:23:24 2016 done: Sun Nov 6 06:23:25 2016
Total Scan time: 7.150 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]