Result of FASTA (omim) for
pFN21AE9634
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9634, 1374 aa
1>>>pF1KE9634 1374 - 1374 aa - 1374 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.4173+/-0.000542; mu= -28.9113+/- 0.034
mean_var=833.6157+/-170.911, 0's: 0 Z-trim(123.0): 95 B-trim: 0 in 0/60
Lambda= 0.044421
statistics sampled from 41838 (41937) to 41838 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.768), E-opt: 0.2 (0.492), width: 16
Scan time: 17.640
The best scores are: opt bits E(85289)
NP_037367 (OMIM: 608828) ribonuclease 3 isoform 1 (1374) 9674 636.9 3e-181
XP_005248348 (OMIM: 608828) PREDICTED: ribonucleas (1374) 9674 636.9 3e-181
XP_005248349 (OMIM: 608828) PREDICTED: ribonucleas (1366) 9592 631.7 1.1e-179
XP_011512335 (OMIM: 608828) PREDICTED: ribonucleas (1250) 8623 569.5 5.2e-161
XP_005248350 (OMIM: 608828) PREDICTED: ribonucleas (1343) 7584 503.0 6.1e-141
XP_016864888 (OMIM: 608828) PREDICTED: ribonucleas (1335) 7487 496.8 4.5e-139
NP_001093882 (OMIM: 608828) ribonuclease 3 isoform (1337) 7279 483.4 4.7e-135
XP_005248351 (OMIM: 608828) PREDICTED: ribonucleas (1306) 7162 475.9 8.3e-133
XP_016864889 (OMIM: 608828) PREDICTED: ribonucleas (1329) 7130 473.9 3.5e-132
XP_016864890 (OMIM: 608828) PREDICTED: ribonucleas (1298) 6962 463.1 5.9e-129
XP_016864891 (OMIM: 608828) PREDICTED: ribonucleas ( 806) 5179 348.7 1e-94
>>NP_037367 (OMIM: 608828) ribonuclease 3 isoform 1 [Hom (1374 aa)
initn: 9674 init1: 9674 opt: 9674 Z-score: 3375.1 bits: 636.9 E(85289): 3e-181
Smith-Waterman score: 9674; 99.9% identity (99.9% similar) in 1374 aa overlap (1-1374:1-1374)
10 20 30 40 50 60
pF1KE9 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 PSLERSYKKEYKRSGRSYGLLVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
NP_037 PSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE9 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE9 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE9 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370
pF1KE9 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
1330 1340 1350 1360 1370
>>XP_005248348 (OMIM: 608828) PREDICTED: ribonuclease 3 (1374 aa)
initn: 9674 init1: 9674 opt: 9674 Z-score: 3375.1 bits: 636.9 E(85289): 3e-181
Smith-Waterman score: 9674; 99.9% identity (99.9% similar) in 1374 aa overlap (1-1374:1-1374)
10 20 30 40 50 60
pF1KE9 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 PSLERSYKKEYKRSGRSYGLLVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_005 PSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE9 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE9 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE9 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370
pF1KE9 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
1330 1340 1350 1360 1370
>>XP_005248349 (OMIM: 608828) PREDICTED: ribonuclease 3 (1366 aa)
initn: 5675 init1: 5675 opt: 9592 Z-score: 3346.7 bits: 631.7 E(85289): 1.1e-179
Smith-Waterman score: 9592; 99.3% identity (99.3% similar) in 1374 aa overlap (1-1374:1-1366)
10 20 30 40 50 60
pF1KE9 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 PSLERSYKKEYKRSGRSYGLLVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_005 PSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 Q--------YQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
790 800 810 820 830
850 860 870 880 890 900
pF1KE9 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE9 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE9 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE9 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE9 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE9 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE9 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE9 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370
pF1KE9 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
1320 1330 1340 1350 1360
>>XP_011512335 (OMIM: 608828) PREDICTED: ribonuclease 3 (1250 aa)
initn: 8623 init1: 8623 opt: 8623 Z-score: 3011.6 bits: 569.5 E(85289): 5.2e-161
Smith-Waterman score: 8623; 99.9% identity (99.9% similar) in 1222 aa overlap (1-1222:1-1222)
10 20 30 40 50 60
pF1KE9 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 PSLERSYKKEYKRSGRSYGLLVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_011 PSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE9 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE9 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
::::::::::::::::::::::
XP_011 ITNDKTKRPVALRTKTLADLLEWDLRIGVENGKTQECAYSGIISNLQVIF
1210 1220 1230 1240 1250
>>XP_005248350 (OMIM: 608828) PREDICTED: ribonuclease 3 (1343 aa)
initn: 7294 init1: 7294 opt: 7584 Z-score: 2651.3 bits: 503.0 E(85289): 6.1e-141
Smith-Waterman score: 9390; 97.7% identity (97.7% similar) in 1374 aa overlap (1-1374:1-1343)
10 20 30 40 50 60
pF1KE9 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSR---------------
250 260 270 280
310 320 330 340 350 360
pF1KE9 PSLERSYKKEYKRSGRSYGLLVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
:::: :::::::::::::::::::::::::::::::::::::::
XP_005 ----------------SYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
290 300 310 320
370 380 390 400 410 420
pF1KE9 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE9 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE9 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE9 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE9 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE9 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE9 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE9 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
750 760 770 780 790 800
850 860 870 880 890 900
pF1KE9 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
810 820 830 840 850 860
910 920 930 940 950 960
pF1KE9 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KE9 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KE9 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KE9 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KE9 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KE9 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KE9 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360 1370
pF1KE9 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
1290 1300 1310 1320 1330 1340
>>XP_016864888 (OMIM: 608828) PREDICTED: ribonuclease 3 (1335 aa)
initn: 6158 init1: 3950 opt: 7487 Z-score: 2617.8 bits: 496.8 E(85289): 4.5e-139
Smith-Waterman score: 9308; 97.1% identity (97.1% similar) in 1374 aa overlap (1-1374:1-1335)
10 20 30 40 50 60
pF1KE9 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSR---------------
250 260 270 280
310 320 330 340 350 360
pF1KE9 PSLERSYKKEYKRSGRSYGLLVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
:::: :::::::::::::::::::::::::::::::::::::::
XP_016 ----------------SYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
290 300 310 320
370 380 390 400 410 420
pF1KE9 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE9 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE9 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE9 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE9 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE9 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE9 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE9 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 Q--------YQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
750 760 770 780 790 800
850 860 870 880 890 900
pF1KE9 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
810 820 830 840 850 860
910 920 930 940 950 960
pF1KE9 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KE9 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KE9 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KE9 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KE9 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KE9 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KE9 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360 1370
pF1KE9 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
1290 1300 1310 1320 1330
>>NP_001093882 (OMIM: 608828) ribonuclease 3 isoform 2 [ (1337 aa)
initn: 9399 init1: 6986 opt: 7279 Z-score: 2545.7 bits: 483.4 E(85289): 4.7e-135
Smith-Waterman score: 9328; 97.2% identity (97.2% similar) in 1374 aa overlap (1-1374:1-1337)
10 20 30 40 50 60
pF1KE9 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 PSLERSYKKEYKRSGRSYGLLVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
::::::::::::::: :::::::
NP_001 PSLERSYKKEYKRSGS-------------------------------------RSPSREK
310 320
370 380 390 400 410 420
pF1KE9 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE9 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE9 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE9 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE9 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE9 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE9 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE9 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
750 760 770 780 790 800
850 860 870 880 890 900
pF1KE9 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
810 820 830 840 850 860
910 920 930 940 950 960
pF1KE9 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KE9 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KE9 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KE9 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KE9 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KE9 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KE9 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360 1370
pF1KE9 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
1290 1300 1310 1320 1330
>>XP_005248351 (OMIM: 608828) PREDICTED: ribonuclease 3 (1306 aa)
initn: 9187 init1: 6986 opt: 7162 Z-score: 2505.3 bits: 475.9 E(85289): 8.3e-133
Smith-Waterman score: 9054; 95.0% identity (95.0% similar) in 1374 aa overlap (1-1374:1-1306)
10 20 30 40 50 60
pF1KE9 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
::::::::::::::::::::::::::::::::::::::::::::
XP_005 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSS---------------
250 260 270 280
310 320 330 340 350 360
pF1KE9 PSLERSYKKEYKRSGRSYGLLVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
:::::::
XP_005 -----------------------------------------------------RSPSREK
290
370 380 390 400 410 420
pF1KE9 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
300 310 320 330 340 350
430 440 450 460 470 480
pF1KE9 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
360 370 380 390 400 410
490 500 510 520 530 540
pF1KE9 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
420 430 440 450 460 470
550 560 570 580 590 600
pF1KE9 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
480 490 500 510 520 530
610 620 630 640 650 660
pF1KE9 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
540 550 560 570 580 590
670 680 690 700 710 720
pF1KE9 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
600 610 620 630 640 650
730 740 750 760 770 780
pF1KE9 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
660 670 680 690 700 710
790 800 810 820 830 840
pF1KE9 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
720 730 740 750 760 770
850 860 870 880 890 900
pF1KE9 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
780 790 800 810 820 830
910 920 930 940 950 960
pF1KE9 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
840 850 860 870 880 890
970 980 990 1000 1010 1020
pF1KE9 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
900 910 920 930 940 950
1030 1040 1050 1060 1070 1080
pF1KE9 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
960 970 980 990 1000 1010
1090 1100 1110 1120 1130 1140
pF1KE9 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
1020 1030 1040 1050 1060 1070
1150 1160 1170 1180 1190 1200
pF1KE9 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
1080 1090 1100 1110 1120 1130
1210 1220 1230 1240 1250 1260
pF1KE9 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
1140 1150 1160 1170 1180 1190
1270 1280 1290 1300 1310 1320
pF1KE9 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
1200 1210 1220 1230 1240 1250
1330 1340 1350 1360 1370
pF1KE9 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
1260 1270 1280 1290 1300
>>XP_016864889 (OMIM: 608828) PREDICTED: ribonuclease 3 (1329 aa)
initn: 6363 init1: 3950 opt: 7130 Z-score: 2494.1 bits: 473.9 E(85289): 3.5e-132
Smith-Waterman score: 9246; 96.7% identity (96.7% similar) in 1374 aa overlap (1-1374:1-1329)
10 20 30 40 50 60
pF1KE9 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 PSLERSYKKEYKRSGRSYGLLVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
::::::::::::::: :::::::
XP_016 PSLERSYKKEYKRSGS-------------------------------------RSPSREK
310 320
370 380 390 400 410 420
pF1KE9 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE9 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE9 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE9 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE9 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE9 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE9 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE9 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 Q--------YQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
750 760 770 780 790
850 860 870 880 890 900
pF1KE9 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
800 810 820 830 840 850
910 920 930 940 950 960
pF1KE9 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
860 870 880 890 900 910
970 980 990 1000 1010 1020
pF1KE9 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KE9 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KE9 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KE9 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
1100 1110 1120 1130 1140 1150
1210 1220 1230 1240 1250 1260
pF1KE9 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
1160 1170 1180 1190 1200 1210
1270 1280 1290 1300 1310 1320
pF1KE9 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
1220 1230 1240 1250 1260 1270
1330 1340 1350 1360 1370
pF1KE9 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
1280 1290 1300 1310 1320
>>XP_016864890 (OMIM: 608828) PREDICTED: ribonuclease 3 (1298 aa)
initn: 6151 init1: 3950 opt: 6962 Z-score: 2436.1 bits: 463.1 E(85289): 5.9e-129
Smith-Waterman score: 8972; 94.4% identity (94.4% similar) in 1374 aa overlap (1-1374:1-1298)
10 20 30 40 50 60
pF1KE9 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS
::::::::::::::::::::::::::::::::::::::::::::
XP_016 GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSS---------------
250 260 270 280
310 320 330 340 350 360
pF1KE9 PSLERSYKKEYKRSGRSYGLLVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK
:::::::
XP_016 -----------------------------------------------------RSPSREK
290
370 380 390 400 410 420
pF1KE9 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN
300 310 320 330 340 350
430 440 450 460 470 480
pF1KE9 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS
360 370 380 390 400 410
490 500 510 520 530 540
pF1KE9 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA
420 430 440 450 460 470
550 560 570 580 590 600
pF1KE9 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI
480 490 500 510 520 530
610 620 630 640 650 660
pF1KE9 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY
540 550 560 570 580 590
670 680 690 700 710 720
pF1KE9 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA
600 610 620 630 640 650
730 740 750 760 770 780
pF1KE9 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA
660 670 680 690 700 710
790 800 810 820 830 840
pF1KE9 QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 Q--------YQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV
720 730 740 750 760
850 860 870 880 890 900
pF1KE9 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP
770 780 790 800 810 820
910 920 930 940 950 960
pF1KE9 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS
830 840 850 860 870 880
970 980 990 1000 1010 1020
pF1KE9 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR
890 900 910 920 930 940
1030 1040 1050 1060 1070 1080
pF1KE9 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN
950 960 970 980 990 1000
1090 1100 1110 1120 1130 1140
pF1KE9 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL
1010 1020 1030 1040 1050 1060
1150 1160 1170 1180 1190 1200
pF1KE9 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA
1070 1080 1090 1100 1110 1120
1210 1220 1230 1240 1250 1260
pF1KE9 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND
1130 1140 1150 1160 1170 1180
1270 1280 1290 1300 1310 1320
pF1KE9 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA
1190 1200 1210 1220 1230 1240
1330 1340 1350 1360 1370
pF1KE9 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK
1250 1260 1270 1280 1290
1374 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 10:28:40 2016 done: Sun Nov 6 10:28:42 2016
Total Scan time: 17.640 Total Display time: 0.630
Function used was FASTA [36.3.4 Apr, 2011]