Result of FASTA (ccds) for
pFN21AE9629
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9629, 1001 aa
1>>>pF1KE9629 1001 - 1001 aa - 1001 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2644+/-0.000933; mu= 13.7532+/- 0.057
mean_var=133.4077+/-26.348, 0's: 0 Z-trim(110.9): 12 B-trim: 6 in 1/50
Lambda= 0.111041
statistics sampled from 11944 (11953) to 11944 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.367), width: 16
Scan time: 3.450
The best scores are: opt bits E(32554)
CCDS11194.1 TOP3A gene_id:7156|Hs108|chr17 (1001) 6931 1122.3 0
CCDS13797.1 TOP3B gene_id:8940|Hs108|chr22 ( 862) 1392 234.9 5.4e-61
>>CCDS11194.1 TOP3A gene_id:7156|Hs108|chr17 (1001 aa)
initn: 6931 init1: 6931 opt: 6931 Z-score: 6003.2 bits: 1122.3 E(32554): 0
Smith-Waterman score: 6931; 100.0% identity (100.0% similar) in 1001 aa overlap (1-1001:1-1001)
10 20 30 40 50 60
pF1KE9 MIFPVARYALRWLRRPEDRAFSRAAMEMALRGVRKVLCVAEKNDAAKGIADLLSNGRMRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MIFPVARYALRWLRRPEDRAFSRAAMEMALRGVRKVLCVAEKNDAAKGIADLLSNGRMRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 REGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 REGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 YCPENFVDIKKTLERETRQCQALVIWTDCDREGENIGFEIIHVCKAVKPNLQVLRARFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 YCPENFVDIKKTLERETRQCQALVIWTDCDREGENIGFEIIHVCKAVKPNLQVLRARFSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 ITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 YGSCQFPTLGFVVERFKAIQAFVPEIFHRIKVTHDHKDGIVEFNWKRHRLFNHTACLVLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 YGSCQFPTLGFVVERFKAIQAFVPEIFHRIKVTHDHKDGIVEFNWKRHRLFNHTACLVLY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 QLCVEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QLCVEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 SYPRTETNIFPRDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SYPRTETNIFPRDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 KYTNNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KYTNNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 YPYDHWSDKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 YPYDHWSDKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 HIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 DKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNGTELAQQEDIYPAMPEPIRKCPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNGTELAQQEDIYPAMPEPIRKCPQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 CNKDMVLKTKKNGGFYLSCMGFPECRSAVWLPDSVLEASRDSSVCPVCQPHPVYRLKLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 CNKDMVLKTKKNGGFYLSCMGFPECRSAVWLPDSVLEASRDSSVCPVCQPHPVYRLKLKF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 KRGSLPPTMPLEFVCCIGGCDDTLREILDLRFSGGPPRASQPSGRLQANQSLNRMDNSQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KRGSLPPTMPLEFVCCIGGCDDTLREILDLRFSGGPPRASQPSGRLQANQSLNRMDNSQH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 PQPADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PQPADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCNG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 GSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 QPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLES
910 920 930 940 950 960
970 980 990 1000
pF1KE9 EARSKRPRASSSDMGSTAKKPRKCSLCHQPGHTRPFCPQNR
:::::::::::::::::::::::::::::::::::::::::
CCDS11 EARSKRPRASSSDMGSTAKKPRKCSLCHQPGHTRPFCPQNR
970 980 990 1000
>>CCDS13797.1 TOP3B gene_id:8940|Hs108|chr22 (862 aa)
initn: 1230 init1: 425 opt: 1392 Z-score: 1208.6 bits: 234.9 E(32554): 5.4e-61
Smith-Waterman score: 1431; 36.2% identity (62.2% similar) in 749 aa overlap (33-756:1-742)
10 20 30 40 50 60
pF1KE9 FPVARYALRWLRRPEDRAFSRAAMEMALRGVRKVLCVAEKNDAAKGIADLLSNGRMRRRE
.. :: :::: . :..:: .:: : . ..
CCDS13 MKTVLMVAEKPSLAQSIAKILSRGSLSSHK
10 20 30
70 80 90 100 110 120
pF1KE9 GLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLLAHDFQMQFRKWQSCNPLVLF-EAEIEKY
::. ...:. . :: : . :::: ::... :: .. ::.. .: :: .: ::
CCDS13 GLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMTLDFLGKYNKWDKVDPAELFSQAPTEKK
40 50 60 70 80 90
130 140 150 160 170
pF1KE9 CPENFVDIKKTLERETRQCQALVIWTDCDREGENIGFEIIHVC-----KAVKPNLQVLRA
. ... : :. : : :. .:.: :::.::::: ::.. . :: . :.::
CCDS13 EANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFRA
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE9 RFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAE
::: :: . .: : :::. . .::.::::::::: ::::::: .: . . :
CCDS13 RFSSITDTDICNAMACLGEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGD-LDS
160 170 180 190 200
240 250 260 270 280 290
pF1KE9 QLISYGSCQFPTLGFVVERFKAIQAFVPEIFH--RIKVTHDHKDGIVEFNWKRHRLFNHT
.:::.: :: ::::: ::: ::.: :: . . ::. : :: . ..: : :.:..
CCDS13 SLISFGPCQTPTLGFCVERHDKIQSFKPETYWVLQAKVNTD-KDRSLLLDWDRVRVFDRE
210 220 230 240 250 260
300 310 320 330 340 350
pF1KE9 ACLVLYQLCVEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKL
.. .. . : : . : :.: :: ::.:::. ..:: .: .. ...:. ::.:
CCDS13 IAQMFLNMTKLEKEAQVEATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQHAMQTAERL
270 280 290 300 310 320
360 370 380 390 400 410
pF1KE9 YTQGYISYPRTETNIFPRDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAH
:::::::::::::. .:....: ..::. : :. .. .: .: ::.:. . . :
CCDS13 YTQGYISYPRTETTHYPENFDLKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGD-H
330 340 350 360 370 380
420 430 440 450 460 470
pF1KE9 PPIHPTKYTNN--LQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMI
::: : : ... : :: ::::.:.:::.: :.: . ..:. . :. : :. : .
CCDS13 PPITPMKSATEAELGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTV
390 400 410 420 430 440
480 490 500 510 520 530
pF1KE9 LARNYLDVYPYDHWS-DKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHG
:. .. .:.:.. .. ::. ..:. : . :.:.. .:.:: ::::.::.::::::
CCDS13 LSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGEVKMLEKQTNPPDYLTEAELITLMEKHG
450 460 470 480 490 500
540 550 560 570 580 590
pF1KE9 IGTDATHAEHIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEAD
:::::. ::..: : :: . .:. : .::. ::.:: .. :. : .:. .: .
CCDS13 IGTDASIPVHINNICQRNYVTVESGRRLKPTNLGIVLVHGYYKIDAELVLPTIRSAVEKQ
510 520 530 540 550 560
600 610 620 630 640
pF1KE9 LKLICDGKKDKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFG----NGTELAQQEDI
:.:: .:: : :: . .. .:. : : . .:: . :. .: :..
CCDS13 LNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRCGKC
570 580 590 600 610 620
650 660 670 680 690 700
pF1KE9 YPAMP----EPIR-KCPQCNKDMVLKTKKNGGFY--LSCMGFPECRSAVWLPDSVLEASR
. : .: : .: .:.. ..: . . .: : : . . . ..: : ..
CCDS13 HRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKLYKELRC-PLDDFELVLWSSGS---RGK
630 640 650 660 670 680
710 720 730 740 750
pF1KE9 DSSVCPVCQPHPVYR-LK--LKFKRGSLPPTMPLEFVCCIGGCDDTLREILDLRFSGGPP
. .:: : :: .: .: . .. . : . . :: : . .: : ..::
CCDS13 SYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSMLGIGQCVECESGVLVLDPTSGPK
690 700 710 720 730 740
760 770 780 790 800 810
pF1KE9 RASQPSGRLQANQSLNRMDNSQHPQPADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQ
CCDS13 WKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLDVDFNKAKSPLPGDETQHMGCVFC
750 760 770 780 790 800
1001 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:47:06 2016 done: Mon Nov 7 18:47:06 2016
Total Scan time: 3.450 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]