Result of FASTA (omim) for
pFN21AE9625
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9625, 779 aa
1>>>pF1KE9625 779 - 779 aa - 779 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5018+/-0.000508; mu= 14.5426+/- 0.031
mean_var=97.8287+/-18.774, 0's: 0 Z-trim(109.9): 52 B-trim: 24 in 2/52
Lambda= 0.129670
statistics sampled from 18067 (18110) to 18067 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.558), E-opt: 0.2 (0.212), width: 16
Scan time: 12.110
The best scores are: opt bits E(85289)
NP_004715 (OMIM: 603954) centromere/kinetochore pr ( 779) 5026 951.7 0
XP_016874048 (OMIM: 603954) PREDICTED: centromere/ ( 559) 3633 691.0 3.5e-198
XP_016874047 (OMIM: 603954) PREDICTED: centromere/ ( 715) 3094 590.3 9.9e-168
>>NP_004715 (OMIM: 603954) centromere/kinetochore protei (779 aa)
initn: 5026 init1: 5026 opt: 5026 Z-score: 5085.1 bits: 951.7 E(85289): 0
Smith-Waterman score: 5026; 100.0% identity (100.0% similar) in 779 aa overlap (1-779:1-779)
10 20 30 40 50 60
pF1KE9 MASFVTEVLAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MASFVTEVLAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 EYNCALTEKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EYNCALTEKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 WQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 LKSFGQMLLKYILRPLASCPSLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LKSFGQMLLKYILRPLASCPSLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 EVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 YEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 NTVKIIPDSKINVPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NTVKIIPDSKINVPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRIS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 ESVKKLMELAYQTLLEATTSSDQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESVKKLMELAYQTLLEATTSSDQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 HHNNCMYIAHHLLTLGHQFRLRLAPILCDGTATFVDLVPGFRRLGTECFLAQMRAQKGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HHNNCMYIAHHLLTLGHQFRLRLAPILCDGTATFVDLVPGFRRLGTECFLAQMRAQKGEL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 LERLSSARNFSNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LERLSSARNFSNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 ISEVIGKITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ISEVIGKITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKW
670 680 690 700 710 720
730 740 750 760 770
pF1KE9 MPFKELMMMLQASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MPFKELMMMLQASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK
730 740 750 760 770
>>XP_016874048 (OMIM: 603954) PREDICTED: centromere/kine (559 aa)
initn: 3633 init1: 3633 opt: 3633 Z-score: 3678.9 bits: 691.0 E(85289): 3.5e-198
Smith-Waterman score: 3633; 100.0% identity (100.0% similar) in 559 aa overlap (221-779:1-559)
200 210 220 230 240 250
pF1KE9 PSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSKLKSFGQMLLK
::::::::::::::::::::::::::::::
XP_016 MPPISSVLLAFSVLGELHSKLKSFGQMLLK
10 20 30
260 270 280 290 300 310
pF1KE9 YILRPLASCPSLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVLEVLQKQLLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YILRPLASCPSLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVLEVLQKQLLDL
40 50 60 70 80 90
320 330 340 350 360 370
pF1KE9 PLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQYEEIIQSTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQYEEIIQSTEE
100 110 120 130 140 150
380 390 400 410 420 430
pF1KE9 FENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIHNTVKIIPDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIHNTVKIIPDSK
160 170 180 190 200 210
440 450 460 470 480 490
pF1KE9 INVPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRISESVKKLMELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INVPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRISESVKKLMELA
220 230 240 250 260 270
500 510 520 530 540 550
pF1KE9 YQTLLEATTSSDQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQTLLEATTSSDQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAH
280 290 300 310 320 330
560 570 580 590 600 610
pF1KE9 HLLTLGHQFRLRLAPILCDGTATFVDLVPGFRRLGTECFLAQMRAQKGELLERLSSARNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLLTLGHQFRLRLAPILCDGTATFVDLVPGFRRLGTECFLAQMRAQKGELLERLSSARNF
340 350 360 370 380 390
620 630 640 650 660 670
pF1KE9 SNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTAISEVIGKITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTAISEVIGKITA
400 410 420 430 440 450
680 690 700 710 720 730
pF1KE9 LEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKWMPFKELMMML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKWMPFKELMMML
460 470 480 490 500 510
740 750 760 770
pF1KE9 QASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK
520 530 540 550
>>XP_016874047 (OMIM: 603954) PREDICTED: centromere/kine (715 aa)
initn: 3082 init1: 3082 opt: 3094 Z-score: 3132.3 bits: 590.3 E(85289): 9.9e-168
Smith-Waterman score: 4485; 91.8% identity (91.8% similar) in 779 aa overlap (1-779:1-715)
10 20 30 40 50 60
pF1KE9 MASFVTEVLAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASFVTEVLAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 EYNCALTEKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYNCALTEKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 WQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 LKSFGQMLLKYILRPLASCPSLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVL
::::
XP_016 LKSF--------------------------------------------------------
310 320 330 340 350 360
pF1KE9 EVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --------DLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQ
250 260 270 280 290
370 380 390 400 410 420
pF1KE9 YEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIH
300 310 320 330 340 350
430 440 450 460 470 480
pF1KE9 NTVKIIPDSKINVPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTVKIIPDSKINVPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRIS
360 370 380 390 400 410
490 500 510 520 530 540
pF1KE9 ESVKKLMELAYQTLLEATTSSDQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESVKKLMELAYQTLLEATTSSDQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAI
420 430 440 450 460 470
550 560 570 580 590 600
pF1KE9 HHNNCMYIAHHLLTLGHQFRLRLAPILCDGTATFVDLVPGFRRLGTECFLAQMRAQKGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHNNCMYIAHHLLTLGHQFRLRLAPILCDGTATFVDLVPGFRRLGTECFLAQMRAQKGEL
480 490 500 510 520 530
610 620 630 640 650 660
pF1KE9 LERLSSARNFSNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LERLSSARNFSNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTA
540 550 560 570 580 590
670 680 690 700 710 720
pF1KE9 ISEVIGKITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISEVIGKITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKW
600 610 620 630 640 650
730 740 750 760 770
pF1KE9 MPFKELMMMLQASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPFKELMMMLQASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK
660 670 680 690 700 710
779 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 06:35:33 2016 done: Sun Nov 6 06:35:35 2016
Total Scan time: 12.110 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]