Result of FASTA (omim) for
pFN21AE9604
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9604, 219 aa
1>>>pF1KE9604 219 - 219 aa - 219 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4400+/-0.000415; mu= -2.9909+/- 0.026
mean_var=262.7478+/-52.695, 0's: 0 Z-trim(120.4): 43 B-trim: 859 in 2/57
Lambda= 0.079123
statistics sampled from 35564 (35612) to 35564 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.418), width: 16
Scan time: 6.550
The best scores are: opt bits E(85289)
NP_005312 (OMIM: 142220) histone H1.4 [Homo sapien ( 219) 1337 164.8 1e-40
NP_005311 (OMIM: 142210) histone H1.3 [Homo sapien ( 221) 1142 142.5 5.1e-34
NP_005310 (OMIM: 142710) histone H1.2 [Homo sapien ( 213) 1106 138.4 8.5e-33
NP_005313 (OMIM: 142711) histone H1.5 [Homo sapien ( 226) 1098 137.5 1.7e-32
NP_005316 (OMIM: 142709) histone H1.1 [Homo sapien ( 215) 877 112.3 6.4e-25
NP_005314 (OMIM: 142712) histone H1t [Homo sapiens ( 207) 563 76.4 3.8e-14
NP_005309 (OMIM: 142708) histone H1.0 [Homo sapien ( 194) 390 56.7 3.2e-08
NP_006017 (OMIM: 602785) histone H1x [Homo sapiens ( 213) 331 50.0 3.7e-06
>>NP_005312 (OMIM: 142220) histone H1.4 [Homo sapiens] (219 aa)
initn: 1337 init1: 1337 opt: 1337 Z-score: 852.1 bits: 164.8 E(85289): 1e-40
Smith-Waterman score: 1337; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:1-219)
10 20 30 40 50 60
pF1KE9 MSETAPAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSETAPAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 KKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKKAKAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKKAKAAK
130 140 150 160 170 180
190 200 210
pF1KE9 PKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
:::::::::::::::::::::::::::::::::::::::
NP_005 PKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
190 200 210
>>NP_005311 (OMIM: 142210) histone H1.3 [Homo sapiens] (221 aa)
initn: 814 init1: 814 opt: 1142 Z-score: 731.7 bits: 142.5 E(85289): 5.1e-34
Smith-Waterman score: 1142; 86.0% identity (94.1% similar) in 221 aa overlap (1-219:1-221)
10 20 30 40 50
pF1KE9 MSETAPAAPAAPAPAEKTPVKKKARKS-AGAAKRKASGPPVSELITKAVAASKERSGVSL
:::::: ::. :::::::::::::.:. : :.::::::::::::::::::::::::::::
NP_005 MSETAPLAPTIPAPAEKTPVKKKAKKAGATAGKRKASGPPVSELITKAVAASKERSGVSL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_005 AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKPK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 AKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKK-AKSPKKAKA
:::::::: .:::::::::::..:::::::: ::::::.::::.:::.:: ::: ::.:.
NP_005 AKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKKVKT
130 140 150 160 170 180
180 190 200 210
pF1KE9 AKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
.:::: :::::::: ::::::::..:::..: :::: :::
NP_005 PQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
190 200 210 220
>>NP_005310 (OMIM: 142710) histone H1.2 [Homo sapiens] (213 aa)
initn: 931 init1: 931 opt: 1106 Z-score: 709.7 bits: 138.4 E(85289): 8.5e-33
Smith-Waterman score: 1106; 86.9% identity (93.9% similar) in 214 aa overlap (1-213:1-212)
10 20 30 40 50 60
pF1KE9 MSETAPAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLA
::::::::::: ::::.:::::: :.::.. ::::::::::::::::::::::::::::
NP_005 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_005 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV
70 80 90 100 110 120
130 140 150 160 170
pF1KE9 KKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKK-AKSPKKAKAA
::::..: :::.:::::::::.:.::::::::::::::::::::. .:: ::::::::.:
NP_005 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA
130 140 150 160 170 180
180 190 200 210
pF1KE9 KPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
::::: :: :: ::::::::::..::: : :::
NP_005 KPKKAAKSAAK--AVKPKAAKPKVVKPKKAAPKKK
190 200 210
>>NP_005313 (OMIM: 142711) histone H1.5 [Homo sapiens] (226 aa)
initn: 1125 init1: 652 opt: 1098 Z-score: 704.5 bits: 137.5 E(85289): 1.7e-32
Smith-Waterman score: 1098; 84.7% identity (91.0% similar) in 222 aa overlap (1-218:1-220)
10 20 30 40 50
pF1KE9 MSETAPAAPAAPAPAEKTPVKKKARKSA---GAAKRKASGPPVSELITKAVAASKERSGV
::::::: :.:::.::.:.:::: :.: :::::::.::::::::::::::::::.:.
NP_005 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 PKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKKAK
:::::::::::::::::. :::: :: ::..:::::::::::::. : ::::::::
NP_005 PKAKKAGAAKAKKPAGAT--PKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAK
130 140 150 160 170
180 190 200 210
pF1KE9 AA-KPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
:: ::::: ::::: :::::::::::.::::::::: : :::
NP_005 AAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
180 190 200 210 220
>>NP_005316 (OMIM: 142709) histone H1.1 [Homo sapiens] (215 aa)
initn: 732 init1: 540 opt: 877 Z-score: 568.4 bits: 112.3 E(85289): 6.4e-25
Smith-Waterman score: 877; 71.2% identity (85.1% similar) in 222 aa overlap (1-219:1-215)
10 20 30 40 50
pF1KE9 MSETAPAAPAAPAPAEKTPVKKKARKSAGAA---KRKASGPPVSELITKAVAASKERSGV
::::.: :::: : :: . :::.: : :: :.: .:: :::::..:...::::.::
NP_005 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
::::::::::::::::::::::::::.:::::::::::::::::::::::::::.: :.:
NP_005 SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 PKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKKAK
: :.:. : : .::.:: ::::::. :::.: ::::::::::. :..:.::: :
NP_005 PGASKV--ATKTKATGASKKLKKATGAS--KKSVK-TPKKAKKPAATR--KSSKNPKKPK
130 140 150 160 170
180 190 200 210
pF1KE9 AAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
..::::. ::::::::::::::: ...:::.::::::: :::
NP_005 TVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
180 190 200 210
>>NP_005314 (OMIM: 142712) histone H1t [Homo sapiens] (207 aa)
initn: 623 init1: 396 opt: 563 Z-score: 374.9 bits: 76.4 E(85289): 3.8e-14
Smith-Waterman score: 594; 53.4% identity (74.9% similar) in 219 aa overlap (1-213:1-207)
10 20 30 40 50
pF1KE9 MSETAPAAPAAP--APAEKTPVKKKARKSAG--AAKRKASGPPVSELITKAVAASKERSG
::::.::: :. : :: :.::..:: :: .:.::. . ::.:::.:...:.:: :
NP_005 MSETVPAASASAGVAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 VSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEA
.::.::::::::::::::::::::::.:::::.:: ::::.::::::::::.::. .
NP_005 MSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKST
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 KPKAKKAGAAKAKKPAGA--AKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPK
. ::::. .::.:: . . .:.:: : :: :.:::: :.. : ..: .
NP_005 RSKAKKSVSAKTKKLVLSRDSKSPKTA-----------KTNKRAKKPRATT-PKTVRSGR
130 140 150 160
180 190 200 210
pF1KE9 KAKAAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
:::.:: :. :::.::.: : : .. . .. . : ::
NP_005 KAKGAKGKQQQKSPVKARASKSKLTQHHEVNVRKATSKK
170 180 190 200
>>NP_005309 (OMIM: 142708) histone H1.0 [Homo sapiens] (194 aa)
initn: 334 init1: 214 opt: 390 Z-score: 268.6 bits: 56.7 E(85289): 3.2e-08
Smith-Waterman score: 405; 42.8% identity (64.0% similar) in 222 aa overlap (1-219:1-194)
10 20 30 40 50 60
pF1KE9 MSETAPAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLA
:.:.. .:::: : : : :.:.... : :..:. :. : :.:.: :
NP_005 MTENSTSAPAAK-P-----------KRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQ
10 20 30 40
70 80 90 100 110
pF1KE9 ALKKALAAAGYDVEKN-NSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK
...: . . : : .: .:.:::..: ::. :.: ::::.::::::.: : : : ::
NP_005 SIQKYIKSH-YKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAK---SDE--PK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE9 AKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKK--PAAAAGAKKAKSPKKAK
:... :.:: . ::::. :::.:.:.: : : :. : : : .:::::
NP_005 -KSVAFKKTKKEIKKVATPKKAS---KPKKAASKAPTKKPKATPVKKAKKKLAATPKKAK
110 120 130 140 150
180 190 200 210
pF1KE9 AAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
::: . .:.::. ::: ::: .:::: . : :.:::
NP_005 --KPKTVKAKPVKAS--KPKKAKP--VKPKAKSSAKRAGKKK
160 170 180 190
>>NP_006017 (OMIM: 602785) histone H1x [Homo sapiens] (213 aa)
initn: 282 init1: 164 opt: 331 Z-score: 231.6 bits: 50.0 E(85289): 3.7e-06
Smith-Waterman score: 332; 36.2% identity (64.8% similar) in 210 aa overlap (5-213:18-213)
10 20 30 40
pF1KE9 MSETAPAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKA
: . : . : .: :: ::. .:.: . :.:....
NP_006 MSVELEEALPVTTAEGMAKKVTKAGGSAALSPSKK--RKN---SKKKNQPGKYSQLVVET
10 20 30 40 50
50 60 70 80 90 100
pF1KE9 VAASKERSGVSLAAL-KKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFK
. ::.: ::: . .: . .: ... . .: ..:.::.. ::.:.:::::.::::
NP_006 IRRLGERNGSSLAKIYTEAKKVPWFDQQNGRTYLKYSIKALVQNDTLLQVKGTGANGSFK
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE9 LNKKAASGEAKPKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAG
::.: : .. .... : : :: .:.: :::. .:. .. : : : ...:: .
NP_006 LNRKKLEGGGE---RRGAPAAATAPAPTAHKAKKAAPGAAGSRRADKKPARGQKPEQRSH
120 130 140 150 160 170
170 180 190 200 210
pF1KE9 AKKAKSPKKAKAAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
::. . :: :..: ::. . : .: :: :::::.. ::. : .:
NP_006 -KKGAGAKKDKGGKAKKT--AAAGGKKVK-KAAKPSV--PKVPKGRK
180 190 200 210
219 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 06:28:48 2016 done: Sun Nov 6 06:28:49 2016
Total Scan time: 6.550 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]