Result of FASTA (omim) for
pFN21AE9572
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9572, 374 aa
1>>>pF1KE9572 374 - 374 aa - 374 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.4679+/-0.000344; mu= 22.4315+/- 0.022
mean_var=104.5376+/-25.289, 0's: 0 Z-trim(116.0): 491 B-trim: 2937 in 2/52
Lambda= 0.125441
statistics sampled from 26227 (26867) to 26227 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.315), width: 16
Scan time: 8.920
The best scores are: opt bits E(85289)
NP_002557 (OMIM: 602697) P2Y purinoceptor 11 [Homo ( 374) 2553 472.8 5.8e-133
NP_003941 (OMIM: 602779) proteinase-activated rece ( 385) 366 77.0 8.1e-14
NP_002554 (OMIM: 601167) P2Y purinoceptor 1 [Homo ( 373) 361 76.1 1.5e-13
NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 349 73.8 6.4e-13
NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 349 73.8 6.4e-13
XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 349 73.9 6.7e-13
NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 349 73.9 6.7e-13
NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 349 73.9 6.7e-13
NP_002556 (OMIM: 300038) P2Y purinoceptor 4 [Homo ( 365) 347 73.5 8.6e-13
NP_002555 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 337 71.7 3.1e-12
XP_011543376 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 337 71.7 3.1e-12
XP_016873328 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 337 71.7 3.1e-12
NP_788086 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 337 71.7 3.1e-12
XP_005274076 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 337 71.7 3.1e-12
XP_005274077 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 337 71.7 3.1e-12
XP_005274078 (OMIM: 600041) PREDICTED: P2Y purinoc ( 377) 337 71.7 3.1e-12
NP_788085 (OMIM: 600041) P2Y purinoceptor 2 [Homo ( 377) 337 71.7 3.1e-12
XP_011543379 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 334 71.1 4.1e-12
XP_006718634 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 334 71.1 4.1e-12
NP_789768 (OMIM: 602451) P2Y purinoceptor 6 isofor ( 328) 334 71.1 4.1e-12
NP_789767 (OMIM: 602451) P2Y purinoceptor 6 isofor ( 328) 334 71.1 4.1e-12
XP_011543381 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 334 71.1 4.1e-12
XP_005274079 (OMIM: 602451) PREDICTED: P2Y purinoc ( 328) 334 71.1 4.1e-12
NP_001264136 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 334 71.1 4.1e-12
NP_001264133 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 334 71.1 4.1e-12
NP_789766 (OMIM: 602451) P2Y purinoceptor 6 isofor ( 328) 334 71.1 4.1e-12
NP_001264134 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 334 71.1 4.1e-12
NP_001264135 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 334 71.1 4.1e-12
XP_011543378 (OMIM: 602451) PREDICTED: P2Y purinoc ( 398) 334 71.2 4.6e-12
NP_001264137 (OMIM: 602451) P2Y purinoceptor 6 iso ( 429) 334 71.3 4.8e-12
NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 322 69.0 2e-11
XP_005260196 (OMIM: 602779) PREDICTED: proteinase- ( 273) 320 68.5 2.2e-11
NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 303 65.5 2.1e-10
NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 303 65.5 2.1e-10
NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 303 65.5 2.1e-10
XP_011544481 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 301 65.2 2.7e-10
XP_011544480 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 301 65.2 2.7e-10
XP_005274486 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 301 65.2 2.7e-10
NP_835230 (OMIM: 300525) P2Y purinoceptor 8 [Homo ( 359) 301 65.2 2.7e-10
XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 301 65.2 2.7e-10
XP_005274835 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 301 65.2 2.7e-10
XP_011543934 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 301 65.2 2.7e-10
XP_006724506 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 301 65.5 3.4e-10
XP_006724927 (OMIM: 300525) PREDICTED: P2Y purinoc ( 548) 301 65.5 3.4e-10
XP_016864712 (OMIM: 600933) PREDICTED: proteinase- ( 383) 294 64.0 6.8e-10
NP_005233 (OMIM: 600933) proteinase-activated rece ( 397) 294 64.0 6.9e-10
NP_115943 (OMIM: 606923) hydroxycarboxylic acid re ( 346) 292 63.5 8.2e-10
NP_006009 (OMIM: 606039) hydroxycarboxylic acid re ( 387) 292 63.6 8.8e-10
XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 290 63.2 1.1e-09
XP_005262183 (OMIM: 300086) PREDICTED: lysophospha ( 370) 290 63.2 1.1e-09
>>NP_002557 (OMIM: 602697) P2Y purinoceptor 11 [Homo sap (374 aa)
initn: 2553 init1: 2553 opt: 2553 Z-score: 2508.2 bits: 472.8 E(85289): 5.8e-133
Smith-Waterman score: 2553; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374)
10 20 30 40 50 60
pF1KE9 MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 WHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 SVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 AEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 VGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATA
310 320 330 340 350 360
370
pF1KE9 APKPSEPQSRELSQ
::::::::::::::
NP_002 APKPSEPQSRELSQ
370
>>NP_003941 (OMIM: 602779) proteinase-activated receptor (385 aa)
initn: 364 init1: 273 opt: 366 Z-score: 369.0 bits: 77.0 E(85289): 8.1e-14
Smith-Waterman score: 398; 33.4% identity (61.4% similar) in 290 aa overlap (23-305:71-343)
10 20 30 40 50
pF1KE9 MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILV-VEFLVAVASNGLALY
: :. : : : . ..:.. .:::::.
NP_003 SILPAPRGYPGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALW
50 60 70 80 90 100
60 70 80 90 100 110
pF1KE9 RFSIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTC
.. : : :.... ..::..::: ::.::: :: ..: .::::::: .
NP_003 VLAT--QAPRLPSTMLLMNLAAADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYG
110 120 130 140 150
120 130 140 150 160
pF1KE9 NLLGSVIFITCISLNRYLGIVHPFFARSHLRPKH-AWAVSAAGWVLAALLAMP-TLSFSH
.. :::.... .::.:::..:::. ::. :: .. : .. :.:..:: ::.: ::. .
NP_003 HMYGSVLLLAAVSLDRYLALVHPLRARA-LRGRRLALGLCMAAWLMAAALALPLTLQRQT
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE9 LKRPQQGAGNCSVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALG
.. .. : : : . :.: :. :: ::: :::: : :::
NP_003 FRLARSDRVLCHDALPLD-----AQASHWQPAFT----CLALLGCFLPLLAMLLCYGATL
220 230 240 250 260
230 240 250 260 270 280
pF1KE9 RAVLRSPGMTVAEKLRVAALV-ASGVALYASSYVPYHIMRVLNVD--ARRRWSTRCPSFA
.. : . : .. ::..:.: ::.::. .:: ... .:. . . :.. ...
NP_003 HT-LAASGRRYGHALRLTAVVLASAVAF----FVPSNLLLLLHYSDPSPSAWGNLYGAYV
270 280 290 300 310 320
290 300 310 320 330 340
pF1KE9 -DIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPE
..: .: . :.. : :
NP_003 PSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHSSL
330 340 350 360 370 380
>>NP_002554 (OMIM: 601167) P2Y purinoceptor 1 [Homo sapi (373 aa)
initn: 513 init1: 312 opt: 361 Z-score: 364.3 bits: 76.1 E(85289): 1.5e-13
Smith-Waterman score: 546; 33.0% identity (62.0% similar) in 303 aa overlap (24-324:47-327)
10 20 30 40 50
pF1KE9 MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRF
.::: .: . .. :... .:..:.. :
NP_002 FLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMF
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE9 SIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNL
. ...:: :. .::..:.: .:::: : : . : .:.: :.:.::.: ::
NP_002 -VFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNL
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE9 LGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRP
::..:.:::: .:: :.:.:. . ..:. :.: .:. :..... : : .:
NP_002 YGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYS-----
140 150 160 170 180 190
180 190 200 210 220 230
pF1KE9 QQGAGNCSVARPEACIKCLGT-ADHGLAAYRAYSL-VLAGLGCGLPLLLTLAAYGALGRA
:.: .: . : : : .:. : .: ::. . ... : .::.: :. :: . ::
NP_002 --GTG----VRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFC-VPLVLILGCYGLIVRA
200 210 220 230 240
240 250 260 270 280 290
pF1KE9 VLRSPGMTVAEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQA
.. . . . . :: ....: ::.:.:.:...:. :: ..: : :
NP_002 LIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQT--P-------A
250 260 270 280 290
300 310 320 330 340 350
pF1KE9 TAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTG
:.. :. ::: ::: : :: :.::. :
NP_002 MCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKS
300 310 320 330 340 350
360 370
pF1KE9 QALPLNATAAPKPSEPQSRELSQ
NP_002 EDMTLNILPEFKQNGDTSL
360 370
>>NP_001154889 (OMIM: 603071) uracil nucleotide/cysteiny (339 aa)
initn: 342 init1: 312 opt: 349 Z-score: 353.0 bits: 73.8 E(85289): 6.4e-13
Smith-Waterman score: 421; 32.5% identity (61.0% similar) in 277 aa overlap (14-284:14-271)
10 20 30 40 50
pF1KE9 MAANVSGAKSCPANF-LAAADD--KLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRK
:: ::.:.. . . ... .. . ...:..:...: :::. : ::
NP_001 MNGLEVAPPGLITNFSLATAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLF-IRD
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 QRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSV
.. :: :: ..:::.:: :.:.:: .: . .:: .:: :::: ::: :. .:.
NP_001 HKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 IFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGA
:.:::: .:.:.:::: . . :: .: . : ::..:. : : ::
NP_001 YFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLV-----SPQTVQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 GNCSVARPEACIKCLGT-ADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSP
: .: .:.. :.: ..:: ... .:.. :.. : . :. ::.
NP_001 TNHTV----VCLQLYREKASH-------HALVSLAVAFTFPFITTVTCYLLIIRS-LRQ-
180 190 200 210 220
240 250 260 270 280 290
pF1KE9 GMTVAEKLRVAA--LVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAA
:. : ..:.. : ..: .:.. .::::. : . : : .. : .
NP_001 GLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILALANRI
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE9 LELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQAL
NP_001 TSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESSLSAKSEL
290 300 310 320 330
>>NP_001154888 (OMIM: 603071) uracil nucleotide/cysteiny (339 aa)
initn: 342 init1: 312 opt: 349 Z-score: 353.0 bits: 73.8 E(85289): 6.4e-13
Smith-Waterman score: 421; 32.5% identity (61.0% similar) in 277 aa overlap (14-284:14-271)
10 20 30 40 50
pF1KE9 MAANVSGAKSCPANF-LAAADD--KLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRK
:: ::.:.. . . ... .. . ...:..:...: :::. : ::
NP_001 MNGLEVAPPGLITNFSLATAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLF-IRD
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 QRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSV
.. :: :: ..:::.:: :.:.:: .: . .:: .:: :::: ::: :. .:.
NP_001 HKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 IFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGA
:.:::: .:.:.:::: . . :: .: . : ::..:. : : ::
NP_001 YFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLV-----SPQTVQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 GNCSVARPEACIKCLGT-ADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSP
: .: .:.. :.: ..:: ... .:.. :.. : . :. ::.
NP_001 TNHTV----VCLQLYREKASH-------HALVSLAVAFTFPFITTVTCYLLIIRS-LRQ-
180 190 200 210 220
240 250 260 270 280 290
pF1KE9 GMTVAEKLRVAA--LVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAA
:. : ..:.. : ..: .:.. .::::. : . : : .. : .
NP_001 GLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILALANRI
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE9 LELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQAL
NP_001 TSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESSLSAKSEL
290 300 310 320 330
>>XP_016859322 (OMIM: 603071) PREDICTED: uracil nucleoti (367 aa)
initn: 342 init1: 312 opt: 349 Z-score: 352.6 bits: 73.9 E(85289): 6.7e-13
Smith-Waterman score: 421; 32.5% identity (61.0% similar) in 277 aa overlap (14-284:42-299)
10 20 30 40
pF1KE9 MAANVSGAKSCPANF-LAAADD--KLSGFQGDFLWPILVVEFL
:: ::.:.. . . ... .. . ...:.
XP_016 KPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENMLFASFYLLDFI
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE9 VAVASNGLALYRFSIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEA
.:...: :::. : :: .. :: :: ..:::.:: :.:.:: .: . .:: .::
XP_016 LALVGNTLALWLF-IRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEI
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE9 ACRLERFLFTCNLLGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALL
:::: ::: :. .:. :.:::: .:.:.:::: . . :: .: . : ::..:.
XP_016 ACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVA
140 150 160 170 180 190
170 180 190 200 210
pF1KE9 AMPTLSFSHLKRPQQGAGNCSVARPEACIKCLGT-ADHGLAAYRAYSLVLAGLGCGLPLL
: : :: : .: .:.. :.: ..:: ... .:..
XP_016 MAPLLV-----SPQTVQTNHTV----VCLQLYREKASH-------HALVSLAVAFTFPFI
200 210 220 230
220 230 240 250 260 270
pF1KE9 LTLAAYGALGRAVLRSPGMTVAEKLRVAA--LVASGVALYASSYVPYHIMRVLNVDARRR
:.. : . :. ::. :. : ..:.. : ..: .:.. .::::. : . : :
XP_016 TTVTCYLLIIRS-LRQ-GLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRS
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 WSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPG
.. : .
XP_016 HGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSF
300 310 320 330 340 350
>>NP_005282 (OMIM: 603071) uracil nucleotide/cysteinyl l (367 aa)
initn: 342 init1: 312 opt: 349 Z-score: 352.6 bits: 73.9 E(85289): 6.7e-13
Smith-Waterman score: 421; 32.5% identity (61.0% similar) in 277 aa overlap (14-284:42-299)
10 20 30 40
pF1KE9 MAANVSGAKSCPANF-LAAADD--KLSGFQGDFLWPILVVEFL
:: ::.:.. . . ... .. . ...:.
NP_005 KPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENMLFASFYLLDFI
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE9 VAVASNGLALYRFSIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEA
.:...: :::. : :: .. :: :: ..:::.:: :.:.:: .: . .:: .::
NP_005 LALVGNTLALWLF-IRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEI
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE9 ACRLERFLFTCNLLGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALL
:::: ::: :. .:. :.:::: .:.:.:::: . . :: .: . : ::..:.
NP_005 ACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVA
140 150 160 170 180 190
170 180 190 200 210
pF1KE9 AMPTLSFSHLKRPQQGAGNCSVARPEACIKCLGT-ADHGLAAYRAYSLVLAGLGCGLPLL
: : :: : .: .:.. :.: ..:: ... .:..
NP_005 MAPLLV-----SPQTVQTNHTV----VCLQLYREKASH-------HALVSLAVAFTFPFI
200 210 220 230
220 230 240 250 260 270
pF1KE9 LTLAAYGALGRAVLRSPGMTVAEKLRVAA--LVASGVALYASSYVPYHIMRVLNVDARRR
:.. : . :. ::. :. : ..:.. : ..: .:.. .::::. : . : :
NP_005 TTVTCYLLIIRS-LRQ-GLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRS
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 WSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPG
.. : .
NP_005 HGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSF
300 310 320 330 340 350
>>NP_001154887 (OMIM: 603071) uracil nucleotide/cysteiny (367 aa)
initn: 342 init1: 312 opt: 349 Z-score: 352.6 bits: 73.9 E(85289): 6.7e-13
Smith-Waterman score: 421; 32.5% identity (61.0% similar) in 277 aa overlap (14-284:42-299)
10 20 30 40
pF1KE9 MAANVSGAKSCPANF-LAAADD--KLSGFQGDFLWPILVVEFL
:: ::.:.. . . ... .. . ...:.
NP_001 KPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENMLFASFYLLDFI
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE9 VAVASNGLALYRFSIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEA
.:...: :::. : :: .. :: :: ..:::.:: :.:.:: .: . .:: .::
NP_001 LALVGNTLALWLF-IRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEI
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE9 ACRLERFLFTCNLLGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALL
:::: ::: :. .:. :.:::: .:.:.:::: . . :: .: . : ::..:.
NP_001 ACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVA
140 150 160 170 180 190
170 180 190 200 210
pF1KE9 AMPTLSFSHLKRPQQGAGNCSVARPEACIKCLGT-ADHGLAAYRAYSLVLAGLGCGLPLL
: : :: : .: .:.. :.: ..:: ... .:..
NP_001 MAPLLV-----SPQTVQTNHTV----VCLQLYREKASH-------HALVSLAVAFTFPFI
200 210 220 230
220 230 240 250 260 270
pF1KE9 LTLAAYGALGRAVLRSPGMTVAEKLRVAA--LVASGVALYASSYVPYHIMRVLNVDARRR
:.. : . :. ::. :. : ..:.. : ..: .:.. .::::. : . : :
NP_001 TTVTCYLLIIRS-LRQ-GLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRS
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 WSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPG
.. : .
NP_001 HGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSF
300 310 320 330 340 350
>>NP_002556 (OMIM: 300038) P2Y purinoceptor 4 [Homo sapi (365 aa)
initn: 413 init1: 308 opt: 347 Z-score: 350.7 bits: 73.5 E(85289): 8.6e-13
Smith-Waterman score: 447; 30.9% identity (54.4% similar) in 353 aa overlap (26-365:29-355)
10 20 30 40 50
pF1KE9 MAANVSGAKSCPANFLAAADDKLSGFQGDF---LWPI-LVVEFLVAVASNGLALYRF
:. :: : :. .: :..... :. .:. :
NP_002 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 SIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNL
: . ::: .... .::.:: : .:.:: : : .:: .: :.. :::: ::
NP_002 -IFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNL
70 80 90 100 110
120 130 140 150 160 170
pF1KE9 LGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRP
::.:.::::..::::: ::. : ::. : . : :...: .:.: : .
NP_002 YCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 QQGAGNCSVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVL
. ...::: :: : .: .. :: :.: :.::. :: ..: .
NP_002 GTTVLCHDTTRPEEF-------DH----YVHFSSAVMGLLFGVPCLVTLVCYGLMARRLY
180 190 200 210 220
240 250 260 270 280 290
pF1KE9 RS-PGMT-VAEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQA
. :: . . .:: .: ....: .::.:: :.. :: . : . .
NP_002 QPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARL-LEADCRVLNIVN--
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE9 TAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRH-CPGYRDSWNPEDAKST
: :.: : : :. :.::. . . :. : : . . :. : :.
NP_002 ---------VVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQ--PRTAASS
290 300 310 320 330
360 370
pF1KE9 GQ--ALPLNAT----AAPKPSEPQSRELSQ
.:: ... :.:. :
NP_002 LALVSLPEDSSCRWAATPQDSSCSTPRADRL
340 350 360
>>NP_002555 (OMIM: 600041) P2Y purinoceptor 2 [Homo sapi (377 aa)
initn: 291 init1: 268 opt: 337 Z-score: 340.7 bits: 71.7 E(85289): 3.1e-12
Smith-Waterman score: 396; 29.8% identity (55.3% similar) in 309 aa overlap (26-324:27-309)
10 20 30 40 50
pF1KE9 MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEF----LVAVASNGLALYRFSI
:. :: . .: : . .... :..::: :
NP_002 MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVLGLCLNAVALYIFLC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 RKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLG
: . :. .... .::::: : : .:: :. : :: .. . :.: :::: ::
NP_002 R-LKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYC
70 80 90 100 110
120 130 140 150 160 170
pF1KE9 SVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQ
:..:.::::..: ::...:. . : ..: :..: :::. :.: : .
NP_002 SILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFV-TTSARG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 GAGNC-SVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLR
: .: ... :: .. . ::: :. :: ..:. . :. : ..: .:.
NP_002 GRVTCHDTSAPEL-----------FSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLK
180 190 200 210 220
240 250 260 270 280
pF1KE9 -----SPGMTVAEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIA
: :. :.. : . .: .:..: ..:.:. :.: . : . : .. :
NP_002 PAYGTSGGLPRAKRKSVRT-IAVVLAVFALCFLPFHVTRTLYY-SFRSLDLSCHTLNAIN
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE9 QATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKS
.: :.: : : :. :.::. :
NP_002 MA-----------YKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARR
290 300 310 320 330
350 360 370
pF1KE9 TGQALPLNATAAPKPSEPQSRELSQ
NP_002 RLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL
340 350 360 370
374 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:26:45 2016 done: Sun Nov 6 13:26:46 2016
Total Scan time: 8.920 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]