Result of FASTA (omim) for
pFN21AE9567
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9567, 488 aa
1>>>pF1KE9567 488 - 488 aa - 488 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9676+/-0.00035; mu= 20.7798+/- 0.022
mean_var=91.6219+/-20.882, 0's: 0 Z-trim(115.3): 397 B-trim: 2517 in 2/55
Lambda= 0.133991
statistics sampled from 25148 (25724) to 25148 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.666), E-opt: 0.2 (0.302), width: 16
Scan time: 10.450
The best scores are: opt bits E(85289)
NP_000949 (OMIM: 601586) prostaglandin E2 receptor ( 488) 3172 623.6 3.8e-178
XP_016865146 (OMIM: 601586) PREDICTED: prostagland ( 326) 1896 376.8 5.1e-104
XP_016865148 (OMIM: 601586) PREDICTED: prostagland ( 313) 1890 375.6 1.1e-103
XP_016865147 (OMIM: 601586) PREDICTED: prostagland ( 325) 1890 375.6 1.1e-103
XP_016865145 (OMIM: 601586) PREDICTED: prostagland ( 350) 1890 375.7 1.2e-103
XP_005259152 (OMIM: 600022) PREDICTED: prostacycli ( 257) 499 106.6 8.6e-23
XP_005259150 (OMIM: 600022) PREDICTED: prostacycli ( 342) 499 106.8 1e-22
NP_000951 (OMIM: 600022) prostacyclin receptor [Ho ( 386) 499 106.8 1.1e-22
NP_000946 (OMIM: 176802) prostaglandin E2 receptor ( 402) 456 98.5 3.7e-20
NP_001268398 (OMIM: 604687,607277) prostaglandin D ( 296) 405 88.5 2.8e-17
XP_005267948 (OMIM: 604687,607277) PREDICTED: pros ( 359) 405 88.6 3.2e-17
NP_000944 (OMIM: 604687,607277) prostaglandin D2 r ( 359) 405 88.6 3.2e-17
NP_000947 (OMIM: 176804,208550) prostaglandin E2 r ( 358) 403 88.2 4.1e-17
NP_942010 (OMIM: 176806) prostaglandin E2 receptor ( 365) 355 78.9 2.6e-14
NP_942009 (OMIM: 176806) prostaglandin E2 receptor ( 374) 355 79.0 2.7e-14
NP_942008 (OMIM: 176806) prostaglandin E2 receptor ( 388) 355 79.0 2.7e-14
NP_942012 (OMIM: 176806) prostaglandin E2 receptor ( 390) 355 79.0 2.7e-14
NP_001119516 (OMIM: 176806) prostaglandin E2 recep ( 390) 355 79.0 2.7e-14
NP_942007 (OMIM: 176806) prostaglandin E2 receptor ( 390) 355 79.0 2.7e-14
XP_011540112 (OMIM: 176806) PREDICTED: prostagland ( 410) 355 79.0 2.8e-14
NP_942011 (OMIM: 176806) prostaglandin E2 receptor ( 418) 355 79.0 2.9e-14
XP_011526516 (OMIM: 188070,614009) PREDICTED: thro ( 343) 313 70.8 7e-12
NP_001051 (OMIM: 188070,614009) thromboxane A2 rec ( 343) 313 70.8 7e-12
NP_963998 (OMIM: 188070,614009) thromboxane A2 rec ( 407) 313 70.9 7.8e-12
NP_000670 (OMIM: 104220) alpha-1B adrenergic recep ( 520) 307 69.8 2.1e-11
NP_000612 (OMIM: 103780,164230,181500,182135,60678 ( 471) 279 64.4 8.2e-10
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328) 270 62.5 2.1e-09
XP_011532740 (OMIM: 104220) PREDICTED: alpha-1B ad ( 389) 265 61.6 4.7e-09
XP_011532739 (OMIM: 104220) PREDICTED: alpha-1B ad ( 402) 265 61.6 4.8e-09
XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B ad ( 331) 264 61.3 4.8e-09
XP_005265875 (OMIM: 104220) PREDICTED: alpha-1B ad ( 366) 264 61.4 5.2e-09
XP_011532737 (OMIM: 104220) PREDICTED: alpha-1B ad ( 556) 265 61.8 6e-09
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 248 58.4 5.3e-08
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 248 58.4 5.6e-08
XP_016857362 (OMIM: 600563) PREDICTED: prostagland ( 291) 243 57.2 7.4e-08
NP_001034674 (OMIM: 600563) prostaglandin F2-alpha ( 297) 243 57.2 7.5e-08
NP_000950 (OMIM: 600563) prostaglandin F2-alpha re ( 359) 243 57.3 8.5e-08
NP_473362 (OMIM: 300393,300943) probable G-protein ( 508) 243 57.5 1.1e-07
NP_004942 (OMIM: 605741) G-protein coupled recepto ( 361) 241 56.9 1.1e-07
XP_016875894 (OMIM: 605741) PREDICTED: G-protein c ( 361) 241 56.9 1.1e-07
NP_001243689 (OMIM: 312861) 5-hydroxytryptamine re ( 458) 236 56.1 2.6e-07
NP_000859 (OMIM: 312861) 5-hydroxytryptamine recep ( 458) 236 56.1 2.6e-07
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic ( 408) 234 55.6 3.1e-07
XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 233 55.4 3.2e-07
NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 233 55.4 3.2e-07
NP_000856 (OMIM: 182132) 5-hydroxytryptamine recep ( 365) 220 52.8 1.9e-06
XP_011534091 (OMIM: 182132) PREDICTED: 5-hydroxytr ( 365) 220 52.8 1.9e-06
NP_000674 (OMIM: 104250) alpha-2C adrenergic recep ( 462) 221 53.2 1.9e-06
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 218 52.6 2.9e-06
NP_000669 (OMIM: 104219) alpha-1D adrenergic recep ( 572) 216 52.3 4.3e-06
>>NP_000949 (OMIM: 601586) prostaglandin E2 receptor EP4 (488 aa)
initn: 3172 init1: 3172 opt: 3172 Z-score: 3319.4 bits: 623.6 E(85289): 3.8e-178
Smith-Waterman score: 3172; 100.0% identity (100.0% similar) in 488 aa overlap (1-488:1-488)
10 20 30 40 50 60
pF1KE9 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 QHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 MGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSET
430 440 450 460 470 480
pF1KE9 LNLSEKCI
::::::::
NP_000 LNLSEKCI
>>XP_016865146 (OMIM: 601586) PREDICTED: prostaglandin E (326 aa)
initn: 1890 init1: 1890 opt: 1896 Z-score: 1988.4 bits: 376.8 E(85289): 5.1e-104
Smith-Waterman score: 1896; 95.7% identity (98.0% similar) in 305 aa overlap (1-304:1-305)
10 20 30 40 50 60
pF1KE9 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
190 200 210 220 230 240
250 260 270 280 290
pF1KE9 HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVV-RVFVNQLYQ
::::::::::::::::::::::::::::::::::::::::::::::::: .. ...::.
XP_016 HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVFPKLQMKNLYH
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE9 PSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERS
. :
XP_016 SATYRVAIGASIRQPVISAKFGARSQ
310 320
>>XP_016865148 (OMIM: 601586) PREDICTED: prostaglandin E (313 aa)
initn: 1890 init1: 1890 opt: 1890 Z-score: 1982.3 bits: 375.6 E(85289): 1.1e-103
Smith-Waterman score: 1890; 100.0% identity (100.0% similar) in 289 aa overlap (1-289:1-289)
10 20 30 40 50 60
pF1KE9 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVAINPISHHGRE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG
XP_016 GQKRTPVTFPKNV
310
>>XP_016865147 (OMIM: 601586) PREDICTED: prostaglandin E (325 aa)
initn: 1890 init1: 1890 opt: 1890 Z-score: 1982.1 bits: 375.6 E(85289): 1.1e-103
Smith-Waterman score: 1890; 100.0% identity (100.0% similar) in 289 aa overlap (1-289:1-289)
10 20 30 40 50 60
pF1KE9 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVANWKWSHKTTD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG
XP_016 GMSDECEAHLYIQEKCHKFGFPSCK
310 320
>>XP_016865145 (OMIM: 601586) PREDICTED: prostaglandin E (350 aa)
initn: 1890 init1: 1890 opt: 1890 Z-score: 1981.8 bits: 375.7 E(85289): 1.2e-103
Smith-Waterman score: 1890; 100.0% identity (100.0% similar) in 289 aa overlap (1-289:1-289)
10 20 30 40 50 60
pF1KE9 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVANWKWSHKTTD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG
XP_016 GMSDECEAHLYIQEKCHKFGCEYSSTSYISQVWSEKSVKIQICRPSELLL
310 320 330 340 350
>>XP_005259152 (OMIM: 600022) PREDICTED: prostacyclin re (257 aa)
initn: 532 init1: 358 opt: 499 Z-score: 530.2 bits: 106.6 E(85289): 8.6e-23
Smith-Waterman score: 499; 42.2% identity (67.3% similar) in 211 aa overlap (20-224:17-225)
10 20 30 40 50 60
pF1KE9 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
:.: ..::. ::::: .:. .: ..:. . ..: .:: :
XP_005 MADSCRNLTYVRGSVGPAT-STLMFVAGVVGNGLALGIL-SARRPARPSAFAVLVTG
10 20 30 40 50
70 80 90 100 110
pF1KE9 LAVTDLLGTLLVSPVTIATYMK-----GQWPGGQPLCEYSTFILLFFSLSGLSIICAMSV
::.:::::: ..::.....: . : :: ::. .: . ::.:... :. ::.:
XP_005 LAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 ERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWT
:: ::..: :.:.. : : :.: :.:: ::::::: .:::. . : .:::.
XP_005 ERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 TNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRT-SLGTEQHHAAAAA
. ::.: :::. ..:. : ::: : .: ::.:: :. :::
XP_005 WAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 SVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFV
XP_005 DHLILLALMTVVMAVCSLPLTQ
240 250
>>XP_005259150 (OMIM: 600022) PREDICTED: prostacyclin re (342 aa)
initn: 530 init1: 358 opt: 499 Z-score: 528.7 bits: 106.8 E(85289): 1e-22
Smith-Waterman score: 509; 34.2% identity (60.1% similar) in 316 aa overlap (20-328:17-287)
10 20 30 40 50 60
pF1KE9 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
:.: ..::. ::::: .:. .: ..:. . ..: .:: :
XP_005 MADSCRNLTYVRGSVGPAT-STLMFVAGVVGNGLALGIL-SARRPARPSAFAVLVTG
10 20 30 40 50
70 80 90 100 110
pF1KE9 LAVTDLLGTLLVSPVTIATYMK-----GQWPGGQPLCEYSTFILLFFSLSGLSIICAMSV
::.:::::: ..::.....: . : :: ::. .: . ::.:... :. ::.:
XP_005 LAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 ERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWT
:: ::..: :.:.. : : :.: :.:: ::::::: .:::. . : .:::.
XP_005 ERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 TNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAAS
. ::.: :::. ..:. : ::: : .: ::.:: ...: . :
XP_005 WAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQ---------QKRHQG---S
180 190 200 210 220
240 250 260 270 280 290
pF1KE9 VASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVN
.. : :: .. :.. .::: ..:. .::.::..: .
XP_005 LGPR---------PRTGE------------DEVDHLILLALMTVVMAVCSLPLTMR---G
230 240 250
300 310 320 330 340 350
pF1KE9 QLYQPSLEREV-SKNPDLQAIRIASVNPILDP-WIYILLRKTVLSKAIEKIKCLFCRIGG
....: . .: .:.. :.: : : :.
XP_005 SVFRPVTQSQVLVLGPSI-------VEPDLPPTWLPSASEQAPPLPLHLGFLRGPRPAPP
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE9 SRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRN
XP_005 QWEWHRPWYPLSVCDTWSCHLSSELQFLFL
320 330 340
>>NP_000951 (OMIM: 600022) prostacyclin receptor [Homo s (386 aa)
initn: 659 init1: 358 opt: 499 Z-score: 528.0 bits: 106.8 E(85289): 1.1e-22
Smith-Waterman score: 631; 36.7% identity (62.1% similar) in 335 aa overlap (20-349:17-311)
10 20 30 40 50 60
pF1KE9 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
:.: ..::. ::::: .:. .: ..:. . ..: .:: :
NP_000 MADSCRNLTYVRGSVGPAT-STLMFVAGVVGNGLALGIL-SARRPARPSAFAVLVTG
10 20 30 40 50
70 80 90 100 110
pF1KE9 LAVTDLLGTLLVSPVTIATYMK-----GQWPGGQPLCEYSTFILLFFSLSGLSIICAMSV
::.:::::: ..::.....: . : :: ::. .: . ::.:... :. ::.:
NP_000 LAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 ERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWT
:: ::..: :.:.. : : :.: :.:: ::::::: .:::. . : .:::.
NP_000 ERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 TNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAAS
. ::.: :::. ..:. : ::: : .: ::.:: ...: . :
NP_000 WAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQ---------QKRHQG---S
180 190 200 210 220
240 250 260 270 280 290
pF1KE9 VASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVN
.. : :: .. :.. .::: ..:. .::.::..: :.
NP_000 LGPR---------PRTGE------------DEVDHLILLALMTVVMAVCSLPLTIRCFT-
230 240 250 260
300 310 320 330 340 350
pF1KE9 QLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSR
: :. :.. :: :.:. . :::::::..::.::.:... . :: :
NP_000 QAVAPDSSSEMG---DLLAFRFYAFNPILDPWVFILFRKAVFQRLKLWVCCL-CLGPAHG
270 280 290 300 310
360 370 380 390 400 410
pF1KE9 RERSGQHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLL
NP_000 DSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQSSGSAVGTSSKA
320 330 340 350 360 370
>>NP_000946 (OMIM: 176802) prostaglandin E2 receptor EP1 (402 aa)
initn: 343 init1: 161 opt: 456 Z-score: 482.9 bits: 98.5 E(85289): 3.7e-20
Smith-Waterman score: 467; 30.9% identity (60.9% similar) in 353 aa overlap (2-339:19-361)
10 20 30 40
pF1KE9 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLC
..: : ..... :. ::. .: . .:.:.::.:...:
NP_000 MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSG-ASPA-LPIFSMTLGAVSNLLALALLA
10 20 30 40 50
50 60 70 80 90
pF1KE9 KS----RKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFIL
.. :.... .:: .: .: .::: : .. . ... : :. :.: :.. .
NP_000 QAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGA-CHFLGGCM
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE9 LFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLG
.::.: : . :.:.::: ..... ... :. : :.: :: : . :: .:
NP_000 VFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVG
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE9 SSRLQYPDTWCFIDW-TTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMH-RQF
.:::: ::::: . .: . ..:... .::...::.: :::: . :.
NP_000 RYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRR
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE9 MRRT--SLGTEQH-----HAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQM
:: . : ... :. .::..: . :.. .. .. : : :: . ...:
NP_000 SRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTF--FGGSRSSGSARRARAHDVEM
240 250 260 270 280 290
280 290 300 310 320
pF1KE9 VILLIATSLVVLICSIPLVVRVF--VNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWI
: :.. .: :: :..: : :. . ::.: : . :.:.:: : :::::.
NP_000 VGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQR-----PLFLAVRLASWNQILDPWV
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE9 YILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEI
:::::..:: .
NP_000 YILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
360 370 380 390 400
>>NP_001268398 (OMIM: 604687,607277) prostaglandin D2 re (296 aa)
initn: 445 init1: 218 opt: 405 Z-score: 431.2 bits: 88.5 E(85289): 2.8e-17
Smith-Waterman score: 454; 32.0% identity (61.5% similar) in 309 aa overlap (1-292:1-285)
10 20 30 40 50
pF1KE9 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKS------RKEQKE--T
:..: . . : .. :: : . .:.: :..:::.:. .: .: :. . .
NP_001 MKSPFYRCQNTTSVEKGNSAV-MGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPS
10 20 30 40 50
60 70 80 90 100
pF1KE9 TFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQ-----WPG-GQPLCEYSTFILLFFSLSG
.:: :::::.:::::: :.:::..:.: ... :. . ::. .:.. ::.::.
NP_001 VFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE9 LSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQY-
. ::..: .:...: .:: ... ::..:. .: : .. ::::: ::.:. .::
NP_001 TLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKF-VQYC
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE9 PDTWCFIDWTTNVTAHAA--YSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSL
: :::::. . . . .. :: .:... ..:.:::::::. . : :::...:.
NP_001 PGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRS
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE9 GTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLI
:.. : . :. :. : :.. ..:: ... .
NP_001 CTRD-----CAEPRADGREASPQPLE-----------------ELDHLLLLALMTVLFTM
240 250 260 270
290 300 310 320 330 340
pF1KE9 CSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEK
::.:... :
NP_001 CSLPVIAFVPGVPAKTPGSR
280 290
488 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:14:47 2016 done: Sun Nov 6 17:14:49 2016
Total Scan time: 10.450 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]