Result of FASTA (omim) for
pFN21AE9564
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9564, 402 aa
1>>>pF1KE9564 402 - 402 aa - 402 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9465+/-0.000274; mu= 21.2616+/- 0.017
mean_var=97.7387+/-20.917, 0's: 0 Z-trim(120.7): 80 B-trim: 1946 in 1/54
Lambda= 0.129730
statistics sampled from 36243 (36383) to 36243 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.751), E-opt: 0.2 (0.427), width: 16
Scan time: 10.750
The best scores are: opt bits E(85289)
NP_000946 (OMIM: 176802) prostaglandin E2 receptor ( 402) 2678 511.1 2e-144
XP_016857362 (OMIM: 600563) PREDICTED: prostagland ( 291) 528 108.5 2.2e-23
NP_001034674 (OMIM: 600563) prostaglandin F2-alpha ( 297) 528 108.5 2.2e-23
NP_000950 (OMIM: 600563) prostaglandin F2-alpha re ( 359) 528 108.6 2.5e-23
NP_000949 (OMIM: 601586) prostaglandin E2 receptor ( 488) 456 95.3 3.5e-19
NP_001051 (OMIM: 188070,614009) thromboxane A2 rec ( 343) 428 89.9 1e-17
XP_011526516 (OMIM: 188070,614009) PREDICTED: thro ( 343) 428 89.9 1e-17
NP_963998 (OMIM: 188070,614009) thromboxane A2 rec ( 407) 428 89.9 1.2e-17
NP_942010 (OMIM: 176806) prostaglandin E2 receptor ( 365) 406 85.8 1.9e-16
NP_942009 (OMIM: 176806) prostaglandin E2 receptor ( 374) 406 85.8 1.9e-16
NP_942008 (OMIM: 176806) prostaglandin E2 receptor ( 388) 406 85.8 2e-16
NP_942007 (OMIM: 176806) prostaglandin E2 receptor ( 390) 406 85.8 2e-16
NP_942012 (OMIM: 176806) prostaglandin E2 receptor ( 390) 406 85.8 2e-16
NP_001119516 (OMIM: 176806) prostaglandin E2 recep ( 390) 406 85.8 2e-16
XP_011540112 (OMIM: 176806) PREDICTED: prostagland ( 410) 406 85.8 2e-16
NP_942011 (OMIM: 176806) prostaglandin E2 receptor ( 418) 406 85.8 2.1e-16
XP_016865148 (OMIM: 601586) PREDICTED: prostagland ( 313) 354 76.0 1.5e-13
XP_016865147 (OMIM: 601586) PREDICTED: prostagland ( 325) 351 75.4 2.2e-13
XP_016865146 (OMIM: 601586) PREDICTED: prostagland ( 326) 351 75.4 2.2e-13
XP_016865145 (OMIM: 601586) PREDICTED: prostagland ( 350) 351 75.5 2.3e-13
XP_005259152 (OMIM: 600022) PREDICTED: prostacycli ( 257) 331 71.6 2.5e-12
XP_005259150 (OMIM: 600022) PREDICTED: prostacycli ( 342) 331 71.7 3.1e-12
NP_000951 (OMIM: 600022) prostacyclin receptor [Ho ( 386) 331 71.8 3.3e-12
NP_000947 (OMIM: 176804,208550) prostaglandin E2 r ( 358) 329 71.3 4.1e-12
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic ( 408) 256 57.8 5.8e-08
NP_001268398 (OMIM: 604687,607277) prostaglandin D ( 296) 250 56.5 1e-07
XP_005267948 (OMIM: 604687,607277) PREDICTED: pros ( 359) 250 56.6 1.2e-07
NP_000944 (OMIM: 604687,607277) prostaglandin D2 r ( 359) 250 56.6 1.2e-07
>>NP_000946 (OMIM: 176802) prostaglandin E2 receptor EP1 (402 aa)
initn: 2678 init1: 2678 opt: 2678 Z-score: 2713.9 bits: 511.1 E(85289): 2e-144
Smith-Waterman score: 2678; 100.0% identity (100.0% similar) in 402 aa overlap (1-402:1-402)
10 20 30 40 50 60
pF1KE9 MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR
310 320 330 340 350 360
370 380 390 400
pF1KE9 QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
::::::::::::::::::::::::::::::::::::::::::
NP_000 QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
370 380 390 400
>>XP_016857362 (OMIM: 600563) PREDICTED: prostaglandin F (291 aa)
initn: 624 init1: 369 opt: 528 Z-score: 540.8 bits: 108.5 E(85289): 2.2e-23
Smith-Waterman score: 560; 32.9% identity (61.0% similar) in 313 aa overlap (7-314:1-266)
10 20 30 40 50 60
pF1KE9 MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
.... . . .. :: . ::. . : . .. ::.: .:: ::.:.: .:
XP_016 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKA
10 20 30 40 50
70 80 90 100 110
pF1KE9 AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----PAGGACHFLGG
:.:.. : :.:::....:. ::. ::.: ::... .:.. . .. : ..:
XP_016 YQRFRQK-SKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 CMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLAR
:::: :::::::: ::.:::.:::.:..:..... .... :..: :. .::::.
XP_016 CMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 VGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWR
:..: :::: . :.. . ::. :::.:: ..:.::...:..:::....
XP_016 HRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 RRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEM
: . :..:.: .::
XP_016 ----------------------------------------------SQQHRQGRSHHLEM
240
300 310 320 330 340 350
pF1KE9 VGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLR
: ::..:: ::::::::.:
XP_016 VIQLLAIMCVSCICWSPFLGYRIILNGKEKYKVYEEQSDFLHRK
250 260 270 280 290
>>NP_001034674 (OMIM: 600563) prostaglandin F2-alpha rec (297 aa)
initn: 524 init1: 369 opt: 528 Z-score: 540.7 bits: 108.5 E(85289): 2.2e-23
Smith-Waterman score: 560; 32.9% identity (61.0% similar) in 313 aa overlap (7-314:1-266)
10 20 30 40 50 60
pF1KE9 MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
.... . . .. :: . ::. . : . .. ::.: .:: ::.:.: .:
NP_001 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKA
10 20 30 40 50
70 80 90 100 110
pF1KE9 AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----PAGGACHFLGG
:.:.. : :.:::....:. ::. ::.: ::... .:.. . .. : ..:
NP_001 YQRFRQK-SKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 CMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLAR
:::: :::::::: ::.:::.:::.:..:..... .... :..: :. .::::.
NP_001 CMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 VGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWR
:..: :::: . :.. . ::. :::.:: ..:.::...:..:::....
NP_001 HRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 RRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEM
: . :..:.: .::
NP_001 ----------------------------------------------SQQHRQGRSHHLEM
240
300 310 320 330 340 350
pF1KE9 VGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLR
: ::..:: ::::::::.:
NP_001 VIQLLAIMCVSCICWSPFLGYRIILNGKEKYKVYEEQSDFLHRLQWPTLE
250 260 270 280 290
>>NP_000950 (OMIM: 600563) prostaglandin F2-alpha recept (359 aa)
initn: 785 init1: 369 opt: 528 Z-score: 539.8 bits: 108.6 E(85289): 2.5e-23
Smith-Waterman score: 739; 34.3% identity (62.2% similar) in 394 aa overlap (7-394:1-341)
10 20 30 40 50 60
pF1KE9 MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
.... . . .. :: . ::. . : . .. ::.: .:: ::.:.: .:
NP_000 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKA
10 20 30 40 50
70 80 90 100 110
pF1KE9 AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----PAGGACHFLGG
:.:.. : :.:::....:. ::. ::.: ::... .:.. . .. : ..:
NP_000 YQRFRQK-SKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 CMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLAR
:::: :::::::: ::.:::.:::.:..:..... .... :..: :. .::::.
NP_000 CMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 VGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWR
:..: :::: . :.. . ::. :::.:: ..:.::...:..:::....
NP_000 HRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 RRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEM
: . :..:.: .::
NP_000 ----------------------------------------------SQQHRQGRSHHLEM
240
300 310 320 330 340 350
pF1KE9 VGQLVGIMVVSCICWSPMLVLVA-LAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILL
: ::..:: ::::::::.:: .: ....: : . ..:.:.:.:::::::::::::
NP_000 VIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILL
250 260 270 280 290 300
360 370 380 390 400
pF1KE9 RQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
:.:::..: .: :.. .. :: ::...:
NP_000 RKAVLKNLYKLASQCCGVHV------ISLHIWELSSIKNSLKVAAISESPVAEKSAST
310 320 330 340 350
>>NP_000949 (OMIM: 601586) prostaglandin E2 receptor EP4 (488 aa)
initn: 343 init1: 161 opt: 456 Z-score: 465.4 bits: 95.3 E(85289): 3.5e-19
Smith-Waterman score: 467; 30.9% identity (60.9% similar) in 353 aa overlap (19-361:2-339)
10 20 30 40 50
pF1KE9 MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSG-ASPA-LPIFSMTLGAVSNLLALALLA
..: : ..... :. ::. .: . .:.:.::.:...:
NP_000 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLC
10 20 30 40
60 70 80 90 100 110
pF1KE9 QAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGA-CHFLGGCM
.. :.... .:: .: .: .::: : .. . ... : :. :.: :.. .
NP_000 KS----RKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFIL
50 60 70 80 90
120 130 140 150 160 170
pF1KE9 VFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVG
.::.: : . :.:.::: ..... ... :. : :.: :: : . :: .:
NP_000 LFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLG
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE9 RYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRR
.:::: ::::: . .: . ..:... .::...::.: :::: . :.
NP_000 SSRLQYPDTWCFIDW-TTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMH-RQF
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE9 SRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTF--FGGSRSSGSARRARAHDVEM
:: . : ... :. .::..: . :.. .. .. : : :: . ...:
NP_000 MRR--TSLGTEQH-----HAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQM
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE9 VGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQR-----PLFLAVRLASWNQILDPWV
: :.. .: :: :..: : :. . ::.: : . :.:.:: : :::::.
NP_000 VILLIATSLVVLICSIPLVVRVF--VNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWI
280 290 300 310 320
360 370 380 390 400
pF1KE9 YILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
:::::..:: .
NP_000 YILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEI
330 340 350 360 370 380
>>NP_001051 (OMIM: 188070,614009) thromboxane A2 recepto (343 aa)
initn: 571 init1: 292 opt: 428 Z-score: 438.9 bits: 89.9 E(85289): 1e-17
Smith-Waterman score: 640; 34.9% identity (58.0% similar) in 407 aa overlap (1-392:8-343)
10 20 30 40 50
pF1KE9 MSPC-GPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLL
..:: : :..: : :.:: . : .: .::::
NP_001 MWPNGSSLGPCFRPTNITLE-ERRLIASPWFAASFCV---------------VGLASNLL
10 20 30 40
60 70 80 90 100
pF1KE9 ALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTA-----GRAPAG
::..:: : . :: .:: :. .:. ::. : .. :..:. ..: . :.
NP_001 ALSVLAGARQGGSHTRS--SFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGC
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE9 GACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALA
:.:.: :.:::: ::::: .:: :: .:.:::. . : .: :: ... : :.:::
NP_001 RLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALA
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE9 VALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGL
..:::: :::: .::::.:::. :: .: .. .. ::. :: ... ... ::.:
NP_001 LGLLPLLGVGRYTVQYPGSWCFLTLGAESG--DVAFGLLFSMLGGLSVGLSFLLNTVSVA
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE9 ALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARR
.: .. :: ..:. .:
NP_001 TLCHVY----------------------HGQEAAQ-----------------------QR
230
290 300 310 320 330
pF1KE9 ARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAV---------GGWSSTSLQRPLFLAVR
: .:::..::.:::::. .:: :.::..: .: .: : . .. :.. .:
NP_001 PRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLR
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE9 LASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSG
.:.::::::::::::.:.::::.: :: ... : .:.: :. . :.:.
NP_001 VATWNQILDPWVYILFRRAVLRRL----QPRLSTR--PRSLSLQPQLTQRSGLQ
300 310 320 330 340
400
pF1KE9 LSHF
>>XP_011526516 (OMIM: 188070,614009) PREDICTED: thrombox (343 aa)
initn: 571 init1: 292 opt: 428 Z-score: 438.9 bits: 89.9 E(85289): 1e-17
Smith-Waterman score: 640; 34.9% identity (58.0% similar) in 407 aa overlap (1-392:8-343)
10 20 30 40 50
pF1KE9 MSPC-GPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLL
..:: : :..: : :.:: . : .: .::::
XP_011 MWPNGSSLGPCFRPTNITLE-ERRLIASPWFAASFCV---------------VGLASNLL
10 20 30 40
60 70 80 90 100
pF1KE9 ALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTA-----GRAPAG
::..:: : . :: .:: :. .:. ::. : .. :..:. ..: . :.
XP_011 ALSVLAGARQGGSHTRS--SFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGC
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE9 GACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALA
:.:.: :.:::: ::::: .:: :: .:.:::. . : .: :: ... : :.:::
XP_011 RLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALA
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE9 VALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGL
..:::: :::: .::::.:::. :: .: .. .. ::. :: ... ... ::.:
XP_011 LGLLPLLGVGRYTVQYPGSWCFLTLGAESG--DVAFGLLFSMLGGLSVGLSFLLNTVSVA
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE9 ALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARR
.: .. :: ..:. .:
XP_011 TLCHVY----------------------HGQEAAQ-----------------------QR
230
290 300 310 320 330
pF1KE9 ARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAV---------GGWSSTSLQRPLFLAVR
: .:::..::.:::::. .:: :.::..: .: .: : . .. :.. .:
XP_011 PRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLR
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE9 LASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSG
.:.::::::::::::.:.::::.: :: ... : .:.: :. . :.:.
XP_011 VATWNQILDPWVYILFRRAVLRRL----QPRLSTR--PRSLSLQPQLTQRSGLQ
300 310 320 330 340
400
pF1KE9 LSHF
>>NP_963998 (OMIM: 188070,614009) thromboxane A2 recepto (407 aa)
initn: 571 init1: 292 opt: 428 Z-score: 438.0 bits: 89.9 E(85289): 1.2e-17
Smith-Waterman score: 624; 35.4% identity (57.6% similar) in 384 aa overlap (1-369:8-326)
10 20 30 40 50
pF1KE9 MSPC-GPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLL
..:: : :..: : :.:: . : .: .::::
NP_963 MWPNGSSLGPCFRPTNITLE-ERRLIASPWFAASFCV---------------VGLASNLL
10 20 30 40
60 70 80 90 100
pF1KE9 ALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTA-----GRAPAG
::..:: : . :: .:: :. .:. ::. : .. :..:. ..: . :.
NP_963 ALSVLAGARQGGSHTRS--SFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGC
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE9 GACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALA
:.:.: :.:::: ::::: .:: :: .:.:::. . : .: :: ... : :.:::
NP_963 RLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALA
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE9 VALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGL
..:::: :::: .::::.:::. :: .: .. .. ::. :: ... ... ::.:
NP_963 LGLLPLLGVGRYTVQYPGSWCFLTLGAESG--DVAFGLLFSMLGGLSVGLSFLLNTVSVA
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE9 ALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARR
.: .. :: ..:. .:
NP_963 TLCHVY----------------------HGQEAAQ-----------------------QR
230
290 300 310 320 330
pF1KE9 ARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAV---------GGWSSTSLQRPLFLAVR
: .:::..::.:::::. .:: :.::..: .: .: : . .. :.. .:
NP_963 PRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLR
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE9 LASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSG
.:.::::::::::::.:.::::.: : :
NP_963 VATWNQILDPWVYILFRRAVLRRLQPRLSTRPRRSLTLWPSLEYSGTISAHCNLRLPGSS
300 310 320 330 340 350
400
pF1KE9 LSHF
NP_963 DSRASASRAAGITGVSHCARPCMLFDPEFDLLAGVQLLPFEPPTGKALSRKD
360 370 380 390 400
>>NP_942010 (OMIM: 176806) prostaglandin E2 receptor EP3 (365 aa)
initn: 527 init1: 216 opt: 406 Z-score: 416.3 bits: 85.8 E(85289): 1.9e-16
Smith-Waterman score: 543; 33.6% identity (55.8% similar) in 387 aa overlap (4-362:14-357)
10 20 30 40
pF1KE9 MSPCGPLNLSLAGE-ATTCAAPWVPNTSAVPPSG-----ASPALPIFSMT
: :: : .: : .: : . : :: .: :.:: .
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 LGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA
: :.: ::. ::.. . : :. . .::: .. : :::.:... .:. .: . .
NP_942 TGFVGNALAM-LLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQR
70 80 90 100 110
110 120 130 140 150
pF1KE9 -----PAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALA
:.: : :.: :. ::: :... .::::: ... : .:..... .: .:
NP_942 WEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLL
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE9 AVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGG-------WRQALLAGLFASLGL
.: ..:: ::::. ::.: .:.:::::::. : :. : . ..:. :: :::
NP_942 GVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE9 VALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASA
.:: ... :: :: ..: :: :.. .: .:: .. ..:
NP_942 LALTVTFSCN----LATIKALV---SRCRAKATASQSSAQWG-------RITTETAI---
240 250 260 270 280
280 290 300 310 320
pF1KE9 STFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSS------
::.::: : .::::.:... . . .:
NP_942 -------------------------QLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKT
290 300 310
330 340 350 360 370 380
pF1KE9 -TSLQRP--LFL-AVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLT
: :. .:: :::::: :::::::::.:::. .::..
NP_942 HTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQEEFWGN
320 330 340 350 360
390 400
pF1KE9 PSAWEASSLRSSRHSGLSHF
>>NP_942009 (OMIM: 176806) prostaglandin E2 receptor EP3 (374 aa)
initn: 529 init1: 216 opt: 406 Z-score: 416.2 bits: 85.8 E(85289): 1.9e-16
Smith-Waterman score: 545; 33.2% identity (56.3% similar) in 391 aa overlap (4-365:14-360)
10 20 30 40
pF1KE9 MSPCGPLNLSLAGE-ATTCAAPWVPNTSAVPPSG-----ASPALPIFSMT
: :: : .: : .: : . : :: .: :.:: .
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 LGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA
: :.: ::. ::.. . : :. . .::: .. : :::.:... .:. .: . .
NP_942 TGFVGNALAM-LLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQR
70 80 90 100 110
110 120 130 140 150
pF1KE9 -----PAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALA
:.: : :.: :. ::: :... .::::: ... : .:..... .: .:
NP_942 WEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLL
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE9 AVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGG-------WRQALLAGLFASLGL
.: ..:: ::::. ::.: .:.:::::::. : :. : . ..:. :: :::
NP_942 GVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE9 VALLAALVCNTLSGLALLRARWRR-RSRRPPPASGPDSRRRWGAHGPRSASASSASSIAS
.:: ... :: :: ..: : :.. :.. .: .:: .. ..:
NP_942 LALTVTFSCN----LATIKALVSRCRAK----ATASQSSAQWG-------RITTETAI--
240 250 260 270 280
280 290 300 310 320
pF1KE9 ASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSS-----
::.::: : .::::.:... . . .:
NP_942 --------------------------QLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCK
290 300 310
330 340 350 360 370 380
pF1KE9 --TSLQRP--LFL-AVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGL
: :. .:: :::::: :::::::::.:::. .::.. ..
NP_942 THTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQEEFWGN
320 330 340 350 360 370
390 400
pF1KE9 TPSAWEASSLRSSRHSGLSHF
402 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:25:39 2016 done: Sun Nov 6 13:25:41 2016
Total Scan time: 10.750 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]