Result of FASTA (omim) for
pFN21AE9544
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9544, 466 aa
1>>>pF1KE9544 466 - 466 aa - 466 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7469+/-0.000349; mu= 15.5015+/- 0.022
mean_var=77.9499+/-15.813, 0's: 0 Z-trim(115.7): 274 B-trim: 1381 in 1/51
Lambda= 0.145267
statistics sampled from 25984 (26281) to 25984 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.308), width: 16
Scan time: 8.230
The best scores are: opt bits E(85289)
NP_000155 (OMIM: 137241) gastric inhibitory polype ( 466) 3188 677.7 1.8e-194
NP_001295347 (OMIM: 137241) gastric inhibitory pol ( 430) 2517 537.1 3.6e-152
XP_011525011 (OMIM: 137241) PREDICTED: gastric inh ( 508) 2145 459.2 1.2e-128
XP_011525012 (OMIM: 137241) PREDICTED: gastric inh ( 508) 2145 459.2 1.2e-128
XP_011525018 (OMIM: 137241) PREDICTED: gastric inh ( 291) 1836 394.3 2.4e-109
XP_011525013 (OMIM: 137241) PREDICTED: gastric inh ( 472) 1474 318.5 2.4e-86
XP_016882076 (OMIM: 137241) PREDICTED: gastric inh ( 302) 1216 264.4 3.2e-70
XP_016879935 (OMIM: 125853,138033) PREDICTED: gluc ( 475) 1191 259.2 1.7e-68
XP_006722340 (OMIM: 125853,138033) PREDICTED: gluc ( 477) 1191 259.2 1.8e-68
NP_000151 (OMIM: 125853,138033) glucagon receptor ( 477) 1191 259.2 1.8e-68
XP_011521841 (OMIM: 125853,138033) PREDICTED: gluc ( 444) 1186 258.2 3.4e-68
XP_016879936 (OMIM: 125853,138033) PREDICTED: gluc ( 355) 1148 250.1 7.1e-66
XP_011525017 (OMIM: 137241) PREDICTED: gastric inh ( 369) 1144 249.3 1.3e-65
XP_011525016 (OMIM: 137241) PREDICTED: gastric inh ( 369) 1144 249.3 1.3e-65
XP_016882075 (OMIM: 137241) PREDICTED: gastric inh ( 303) 1051 229.8 8.2e-60
XP_016882074 (OMIM: 137241) PREDICTED: gastric inh ( 344) 1051 229.8 9.1e-60
XP_016882073 (OMIM: 137241) PREDICTED: gastric inh ( 351) 1051 229.8 9.2e-60
XP_011525015 (OMIM: 137241) PREDICTED: gastric inh ( 425) 1051 229.9 1.1e-59
NP_002053 (OMIM: 138032) glucagon-like peptide 1 r ( 463) 1012 221.7 3.4e-57
XP_016866239 (OMIM: 138032) PREDICTED: glucagon-li ( 468) 1012 221.7 3.4e-57
NP_002971 (OMIM: 182098) secretin receptor precurs ( 440) 984 215.8 1.9e-55
NP_004237 (OMIM: 603659) glucagon-like peptide 2 r ( 553) 984 215.9 2.3e-55
XP_016880828 (OMIM: 603659) PREDICTED: glucagon-li ( 559) 977 214.4 6.4e-55
XP_011522379 (OMIM: 603659) PREDICTED: glucagon-li ( 578) 977 214.4 6.5e-55
XP_011509923 (OMIM: 182098) PREDICTED: secretin re ( 445) 967 212.3 2.2e-54
XP_016860159 (OMIM: 182098) PREDICTED: secretin re ( 435) 961 211.0 5.3e-54
XP_005256918 (OMIM: 603659) PREDICTED: glucagon-li ( 400) 946 207.8 4.3e-53
XP_016880830 (OMIM: 603659) PREDICTED: glucagon-li ( 448) 946 207.9 4.8e-53
XP_016880829 (OMIM: 603659) PREDICTED: glucagon-li ( 483) 946 207.9 5.1e-53
XP_005265494 (OMIM: 192321) PREDICTED: vasoactive ( 456) 933 205.1 3.2e-52
XP_016860161 (OMIM: 182098) PREDICTED: secretin re ( 377) 927 203.8 6.5e-52
NP_001238813 (OMIM: 192321) vasoactive intestinal ( 409) 924 203.2 1.1e-51
NP_001238814 (OMIM: 192321) vasoactive intestinal ( 430) 924 203.2 1.1e-51
NP_004615 (OMIM: 192321) vasoactive intestinal pol ( 457) 924 203.3 1.2e-51
XP_011532381 (OMIM: 192321) PREDICTED: vasoactive ( 416) 920 202.4 2e-51
NP_001238811 (OMIM: 192321) vasoactive intestinal ( 416) 920 202.4 2e-51
XP_005265495 (OMIM: 192321) PREDICTED: vasoactive ( 416) 920 202.4 2e-51
XP_005265496 (OMIM: 192321) PREDICTED: vasoactive ( 410) 915 201.3 4e-51
NP_001186566 (OMIM: 102981) pituitary adenylate cy ( 447) 892 196.5 1.2e-49
XP_016860160 (OMIM: 182098) PREDICTED: secretin re ( 409) 887 195.5 2.3e-49
NP_003373 (OMIM: 601970) vasoactive intestinal pol ( 438) 887 195.5 2.5e-49
XP_005249618 (OMIM: 601970) PREDICTED: vasoactive ( 463) 887 195.5 2.6e-49
XP_006716170 (OMIM: 601970) PREDICTED: vasoactive ( 455) 854 188.6 3.1e-47
XP_005249675 (OMIM: 102981) PREDICTED: pituitary a ( 411) 843 186.3 1.4e-46
NP_001109 (OMIM: 102981) pituitary adenylate cycla ( 468) 843 186.3 1.6e-46
NP_000814 (OMIM: 139191,612781) growth hormone-rel ( 423) 801 177.5 6.4e-44
NP_001295188 (OMIM: 601970) vasoactive intestinal ( 422) 797 176.6 1.1e-43
XP_006716171 (OMIM: 601970) PREDICTED: vasoactive ( 392) 788 174.7 4e-43
XP_011514852 (OMIM: 601970) PREDICTED: vasoactive ( 439) 764 169.7 1.4e-41
XP_016868069 (OMIM: 601970) PREDICTED: vasoactive ( 300) 750 166.7 7.9e-41
>>NP_000155 (OMIM: 137241) gastric inhibitory polypeptid (466 aa)
initn: 3188 init1: 3188 opt: 3188 Z-score: 3612.5 bits: 677.7 E(85289): 1.8e-194
Smith-Waterman score: 3188; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)
10 20 30 40 50 60
pF1KE9 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCEN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 TPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 TEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQ
370 380 390 400 410 420
430 440 450 460
pF1KE9 RQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESYC
::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESYC
430 440 450 460
>>NP_001295347 (OMIM: 137241) gastric inhibitory polypep (430 aa)
initn: 2878 init1: 2517 opt: 2517 Z-score: 2853.0 bits: 537.1 E(85289): 3.6e-152
Smith-Waterman score: 2810; 92.3% identity (92.3% similar) in 466 aa overlap (1-466:1-430)
10 20 30 40 50 60
pF1KE9 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPS---
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCEN
:::::::::::::::::::::::::::
NP_001 ---------------------------------VAAGFVLRQCGSDGQWGLWRDHTQCEN
60 70 80
130 140 150 160 170 180
pF1KE9 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE9 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE9 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE9 TPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPV
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE9 TEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQ
330 340 350 360 370 380
430 440 450 460
pF1KE9 RQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESYC
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESYC
390 400 410 420 430
>>XP_011525011 (OMIM: 137241) PREDICTED: gastric inhibit (508 aa)
initn: 2171 init1: 2145 opt: 2145 Z-score: 2430.6 bits: 459.2 E(85289): 1.2e-128
Smith-Waterman score: 3028; 91.6% identity (91.6% similar) in 498 aa overlap (1-456:1-498)
10 20 30 40 50 60
pF1KE9 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCEN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR
250 260 270 280 290 300
310
pF1KE9 TPILMTIL------------------------------------------INFLIFIRIL
:::::::: ::::::::::
XP_011 TPILMTILVGSVPPPPGRPQGFPILGSGLPPPPAPSEWDRGWLSPYLSPQINFLIFIRIL
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE9 GILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEI
370 380 390 400 410 420
380 390 400 410 420 430
pF1KE9 FLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGSGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGSGPG
430 440 450 460 470 480
440 450 460
pF1KE9 EVPTSRGLSSGTLPGPGNEASRELESYC
::::::::::::::::::
XP_011 EVPTSRGLSSGTLPGPGNEASRELESYC
490 500
>>XP_011525012 (OMIM: 137241) PREDICTED: gastric inhibit (508 aa)
initn: 2171 init1: 2145 opt: 2145 Z-score: 2430.6 bits: 459.2 E(85289): 1.2e-128
Smith-Waterman score: 3028; 91.6% identity (91.6% similar) in 498 aa overlap (1-456:1-498)
10 20 30 40 50 60
pF1KE9 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCEN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR
250 260 270 280 290 300
310
pF1KE9 TPILMTIL------------------------------------------INFLIFIRIL
:::::::: ::::::::::
XP_011 TPILMTILVGSVPPPPGRPQGFPILGSGLPPPPAPSEWDRGWLSPYLSPQINFLIFIRIL
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE9 GILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEI
370 380 390 400 410 420
380 390 400 410 420 430
pF1KE9 FLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGSGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGSGPG
430 440 450 460 470 480
440 450 460
pF1KE9 EVPTSRGLSSGTLPGPGNEASRELESYC
::::::::::::::::::
XP_011 EVPTSRGLSSGTLPGPGNEASRELESYC
490 500
>>XP_011525018 (OMIM: 137241) PREDICTED: gastric inhibit (291 aa)
initn: 1836 init1: 1836 opt: 1836 Z-score: 2084.2 bits: 394.3 E(85289): 2.4e-109
Smith-Waterman score: 1836; 100.0% identity (100.0% similar) in 265 aa overlap (1-265:1-265)
10 20 30 40 50 60
pF1KE9 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCEN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR
:::::::::::::::::::::::::
XP_011 LHSLLVLVGGSEEGHFRYYLLLGWGTCTRTRSAGSATKSRPFGGLYGPPSS
250 260 270 280 290
>>XP_011525013 (OMIM: 137241) PREDICTED: gastric inhibit (472 aa)
initn: 1861 init1: 1474 opt: 1474 Z-score: 1671.1 bits: 318.5 E(85289): 2.4e-86
Smith-Waterman score: 2650; 84.3% identity (84.3% similar) in 498 aa overlap (1-456:1-462)
10 20 30 40 50 60
pF1KE9 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPS---
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGLWRDHTQCEN
:::::::::::::::::::::::::::
XP_011 ---------------------------------VAAGFVLRQCGSDGQWGLWRDHTQCEN
60 70 80
130 140 150 160 170 180
pF1KE9 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSF
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE9 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVTQYCVGANYTWLLVEGVY
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE9 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIR
210 220 230 240 250 260
310
pF1KE9 TPILMTIL------------------------------------------INFLIFIRIL
:::::::: ::::::::::
XP_011 TPILMTILVGSVPPPPGRPQGFPILGSGLPPPPAPSEWDRGWLSPYLSPQINFLIFIRIL
270 280 290 300 310 320
320 330 340 350 360 370
pF1KE9 GILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEI
330 340 350 360 370 380
380 390 400 410 420 430
pF1KE9 FLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGSGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGSGPG
390 400 410 420 430 440
440 450 460
pF1KE9 EVPTSRGLSSGTLPGPGNEASRELESYC
::::::::::::::::::
XP_011 EVPTSRGLSSGTLPGPGNEASRELESYC
450 460 470
>>XP_016882076 (OMIM: 137241) PREDICTED: gastric inhibit (302 aa)
initn: 1216 init1: 1216 opt: 1216 Z-score: 1381.7 bits: 264.4 E(85289): 3.2e-70
Smith-Waterman score: 1216; 100.0% identity (100.0% similar) in 181 aa overlap (286-466:122-302)
260 270 280 290 300 310
pF1KE9 FRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRTPILMTILINFLIFI
::::::::::::::::::::::::::::::
XP_016 GGGRLPAQSPGARGRLRGGPLPLLPAPRLGCWERNEVKAIWWIIRTPILMTILINFLIFI
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE9 RILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLG
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE9 FEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQRQLPERAFRALPSGS
220 230 240 250 260 270
440 450 460
pF1KE9 GPGEVPTSRGLSSGTLPGPGNEASRELESYC
:::::::::::::::::::::::::::::::
XP_016 GPGEVPTSRGLSSGTLPGPGNEASRELESYC
280 290 300
>>XP_016879935 (OMIM: 125853,138033) PREDICTED: glucagon (475 aa)
initn: 1412 init1: 894 opt: 1191 Z-score: 1350.5 bits: 259.2 E(85289): 1.7e-68
Smith-Waterman score: 1489; 51.0% identity (74.2% similar) in 453 aa overlap (18-459:13-457)
10 20 30 40 50 60
pF1KE9 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLA
::: : ..:. :...:. : .:...:. ::. :.
XP_016 MPPCQPQRPLLLLLLLLACQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELV
10 20 30 40 50
70 80 90 100 110
pF1KE9 CNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQW-----GL-WRD
:: .:: : :: . :.:: ::::::::::.: ::...:: :::: : :::
XP_016 CNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 HTQCE-NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIH
.::. . :. :. . . .::::::::::::..::::: ::. . .:::::: ::
XP_016 ASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIH
120 130 140 150 160 170
180 190 200 210 220
pF1KE9 INLFTSFMLRAAAILSRDRLL-PRPGPYLGDQ-ALALW--NQALAACRTAQIVTQYCVGA
:::.::.:.:...: : :: : . .::. ... : . :.:.::.: . :: . :
XP_016 ANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE9 NYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWER
:: ::::::.:::.:: :. :.. : :: .::::: :::.::..:. :.::.:::
XP_016 NYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE9 NEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPL
:. ..:::.: :....:::::.::.::. .:..:::.:::. ::..:::.:::::.::
XP_016 NDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPL
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE9 LGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHH
::::::::: ::.:.:.:.:: ::: :..:::::::.::.:::::.:::::::.:: ::.
XP_016 LGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHR
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE9 CRLRRSLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESYC
:: . : ::. .:: .:.::. : :. :. : : :.. :
XP_016 WRLGKVLWEERNTSNHRA------SSSPGHGPPSKELQFGR--GGGSQDSSAETPLAGGL
420 430 440 450 460
XP_016 PRLAESPF
470
>>XP_006722340 (OMIM: 125853,138033) PREDICTED: glucagon (477 aa)
initn: 1437 init1: 894 opt: 1191 Z-score: 1350.5 bits: 259.2 E(85289): 1.8e-68
Smith-Waterman score: 1491; 50.4% identity (73.2% similar) in 466 aa overlap (5-459:9-459)
10 20 30 40 50
pF1KE9 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPP
:.: ::: :. : . : :. :...:. : .:...:. ::
XP_006 MPPCQPQRPLLLLLLLLA-CQPQVPSA------QVMDFLFEKWKLYGDQCHHNLSLLPPP
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 SGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQW-----GL
. :.:: .:: : :: . :.:: ::::::::::.: ::...:: :::: :
XP_006 TELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQ
60 70 80 90 100 110
120 130 140 150 160
pF1KE9 -WRDHTQCE-NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTR
::: .::. . :. :. . . .::::::::::::..::::: ::. . .:::::
XP_006 PWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTR
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE9 NYIHINLFTSFMLRAAAILSRDRLL-PRPGPYLGDQ-ALALW--NQALAACRTAQIVTQY
: :: :::.::.:.:...: : :: : . .::. ... : . :.:.::.: . ::
XP_006 NAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQY
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE9 CVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQ
. ::: ::::::.:::.:: :. :.. : :: .::::: :::.::..:. :.::.:
XP_006 GIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQ
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE9 CWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLT
:: :. ..:::.: :....:::::.::.::. .:..:::.:::. ::..:::.::::
XP_006 CWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLT
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE9 LVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRR
:.::::::::::: ::.:.:.:.:: ::: :..:::::::.::.:::::.:::::::.::
XP_006 LIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRR
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE9 GWHHCRLRRSLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESY
::. :: . : ::. .:: .:.::. : :. :. : : :.. :
XP_006 RWHRWRLGKVLWEERNTSNHRA------SSSPGHGPPSKELQFGR--GGGSQDSSAETPL
420 430 440 450 460
pF1KE9 C
XP_006 AGGLPRLAESPF
470
>>NP_000151 (OMIM: 125853,138033) glucagon receptor prec (477 aa)
initn: 1437 init1: 894 opt: 1191 Z-score: 1350.5 bits: 259.2 E(85289): 1.8e-68
Smith-Waterman score: 1491; 50.4% identity (73.2% similar) in 466 aa overlap (5-459:9-459)
10 20 30 40 50
pF1KE9 MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPP
:.: ::: :. : . : :. :...:. : .:...:. ::
NP_000 MPPCQPQRPLLLLLLLLA-CQPQVPSA------QVMDFLFEKWKLYGDQCHHNLSLLPPP
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 SGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQW-----GL
. :.:: .:: : :: . :.:: ::::::::::.: ::...:: :::: :
NP_000 TELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQ
60 70 80 90 100 110
120 130 140 150 160
pF1KE9 -WRDHTQCE-NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTR
::: .::. . :. :. . . .::::::::::::..::::: ::. . .:::::
NP_000 PWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTR
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE9 NYIHINLFTSFMLRAAAILSRDRLL-PRPGPYLGDQ-ALALW--NQALAACRTAQIVTQY
: :: :::.::.:.:...: : :: : . .::. ... : . :.:.::.: . ::
NP_000 NAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQY
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE9 CVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQ
. ::: ::::::.:::.:: :. :.. : :: .::::: :::.::..:. :.::.:
NP_000 GIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQ
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE9 CWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLT
:: :. ..:::.: :....:::::.::.::. .:..:::.:::. ::..:::.::::
NP_000 CWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLT
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE9 LVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRR
:.::::::::::: ::.:.:.:.:: ::: :..:::::::.::.:::::.:::::::.::
NP_000 LIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRR
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE9 GWHHCRLRRSLGEEQRQLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEASRELESY
::. :: . : ::. .:: .:.::. : :. :. : : :.. :
NP_000 RWHRWRLGKVLWEERNTSNHRA------SSSPGHGPPSKELQFGR--GGGSQDSSAETPL
420 430 440 450 460
pF1KE9 C
NP_000 AGGLPRLAESPF
470
466 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:59:10 2016 done: Mon Nov 7 17:59:11 2016
Total Scan time: 8.230 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]