Result of FASTA (omim) for
pFN21AE9542
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9542, 757 aa
1>>>pF1KE9542 757 - 757 aa - 757 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8220+/-0.000733; mu= 13.9780+/- 0.045
mean_var=317.6017+/-77.524, 0's: 0 Z-trim(109.5): 518 B-trim: 1078 in 1/51
Lambda= 0.071967
statistics sampled from 17050 (17667) to 17050 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.55), E-opt: 0.2 (0.207), width: 16
Scan time: 9.040
The best scores are: opt bits E(85289)
NP_067647 (OMIM: 606654) relaxin receptor 1 isofor ( 757) 5149 550.7 8.2e-156
XP_016864007 (OMIM: 606654) PREDICTED: relaxin rec ( 756) 5132 548.9 2.8e-155
XP_016864010 (OMIM: 606654) PREDICTED: relaxin rec ( 676) 4545 487.9 5.9e-137
XP_016864011 (OMIM: 606654) PREDICTED: relaxin rec ( 675) 4528 486.1 2e-136
NP_001240657 (OMIM: 606654) relaxin receptor 1 iso ( 724) 4460 479.1 2.8e-134
XP_016864008 (OMIM: 606654) PREDICTED: relaxin rec ( 703) 4441 477.1 1.1e-133
XP_016864009 (OMIM: 606654) PREDICTED: relaxin rec ( 703) 4441 477.1 1.1e-133
NP_001240656 (OMIM: 606654) relaxin receptor 1 iso ( 784) 4441 477.2 1.1e-133
XP_011530476 (OMIM: 606654) PREDICTED: relaxin rec ( 783) 4424 475.4 3.8e-133
NP_001240659 (OMIM: 606654) relaxin receptor 1 iso ( 626) 4194 451.4 5.3e-126
NP_001240661 (OMIM: 606654) relaxin receptor 1 iso ( 625) 4034 434.8 5.3e-121
XP_011530477 (OMIM: 606654) PREDICTED: relaxin rec ( 760) 4003 431.7 5.4e-120
XP_016864006 (OMIM: 606654) PREDICTED: relaxin rec ( 759) 3986 429.9 1.8e-119
XP_011530478 (OMIM: 606654) PREDICTED: relaxin rec ( 733) 3340 362.8 2.8e-99
XP_016864015 (OMIM: 606654) PREDICTED: relaxin rec ( 601) 3303 358.9 3.7e-98
NP_001240662 (OMIM: 606654) relaxin receptor 1 iso ( 601) 3303 358.9 3.7e-98
NP_001240658 (OMIM: 606654) relaxin receptor 1 iso ( 709) 3033 330.9 1.1e-89
NP_570718 (OMIM: 219050,606655) relaxin receptor 2 ( 754) 2689 295.3 6.3e-79
XP_016864012 (OMIM: 606654) PREDICTED: relaxin rec ( 385) 2556 281.0 6.5e-75
NP_001159530 (OMIM: 219050,606655) relaxin recepto ( 730) 1943 217.8 1.3e-55
XP_016864013 (OMIM: 606654) PREDICTED: relaxin rec ( 361) 1897 212.5 2.5e-54
XP_016864014 (OMIM: 606654) PREDICTED: relaxin rec ( 352) 1867 209.4 2.1e-53
XP_011530481 (OMIM: 606654) PREDICTED: relaxin rec ( 412) 1848 207.5 9.1e-53
XP_016875878 (OMIM: 219050,606655) PREDICTED: rela ( 383) 1178 137.9 7.6e-32
XP_011531130 (OMIM: 152790,176410,238320) PREDICTE ( 674) 491 67.0 3e-10
NP_000224 (OMIM: 152790,176410,238320) lutropin-ch ( 699) 462 64.0 2.5e-09
XP_011535421 (OMIM: 275200,603372,603373,609152) P ( 671) 447 62.4 7.1e-09
XP_005268094 (OMIM: 275200,603372,603373,609152) P ( 764) 447 62.5 7.5e-09
NP_000360 (OMIM: 275200,603372,603373,609152) thyr ( 764) 447 62.5 7.5e-09
NP_055632 (OMIM: 613356) TLR4 interactor with leuc ( 811) 431 60.9 2.5e-08
NP_060960 (OMIM: 606666,615311) leucine-rich repea ( 951) 426 60.5 3.8e-08
XP_011531036 (OMIM: 136435,233300,276400,608115) P ( 618) 415 59.0 6.8e-08
XP_011531035 (OMIM: 136435,233300,276400,608115) P ( 729) 415 59.1 7.4e-08
XP_006712078 (OMIM: 152790,176410,238320) PREDICTE ( 389) 393 56.4 2.6e-07
XP_016859579 (OMIM: 152790,176410,238320) PREDICTE ( 487) 391 56.4 3.4e-07
XP_011531133 (OMIM: 152790,176410,238320) PREDICTE ( 487) 391 56.4 3.4e-07
XP_005264366 (OMIM: 152790,176410,238320) PREDICTE ( 380) 388 55.9 3.7e-07
XP_011531136 (OMIM: 152790,176410,238320) PREDICTE ( 380) 388 55.9 3.7e-07
XP_016859578 (OMIM: 152790,176410,238320) PREDICTE ( 614) 391 56.5 3.8e-07
NP_004961 (OMIM: 601489,615961) insulin-like growt ( 605) 381 55.5 7.8e-07
NP_001139478 (OMIM: 601489,615961) insulin-like gr ( 643) 381 55.5 8e-07
NP_001245211 (OMIM: 609793) leucine-rich repeat an ( 606) 380 55.4 8.4e-07
XP_016869792 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 380 55.4 8.4e-07
XP_016869796 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 380 55.4 8.4e-07
XP_011516021 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 380 55.4 8.4e-07
XP_016869794 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 380 55.4 8.4e-07
XP_016869795 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 380 55.4 8.4e-07
NP_689783 (OMIM: 609793) leucine-rich repeat and i ( 606) 380 55.4 8.4e-07
XP_011516030 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 380 55.4 8.4e-07
XP_011516026 (OMIM: 609793) PREDICTED: leucine-ric ( 606) 380 55.4 8.4e-07
>>NP_067647 (OMIM: 606654) relaxin receptor 1 isoform 1 (757 aa)
initn: 5149 init1: 5149 opt: 5149 Z-score: 2918.3 bits: 550.7 E(85289): 8.2e-156
Smith-Waterman score: 5149; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)
10 20 30 40 50 60
pF1KE9 MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLELDCDETNLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLELDCDETNLRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 VPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 VPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 LSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 LSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 PLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 PLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 DLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 DLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 RMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 RMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 FGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 FGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 ESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 ESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 IVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 IVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 SMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 SMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 ITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 ITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWV
670 680 690 700 710 720
730 740 750
pF1KE9 EMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
:::::::::::::::::::::::::::::::::::::
NP_067 EMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
730 740 750
>>XP_016864007 (OMIM: 606654) PREDICTED: relaxin recepto (756 aa)
initn: 5130 init1: 2750 opt: 5132 Z-score: 2908.7 bits: 548.9 E(85289): 2.8e-155
Smith-Waterman score: 5132; 99.9% identity (99.9% similar) in 757 aa overlap (1-757:1-756)
10 20 30 40 50 60
pF1KE9 MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLELDCDETNLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLELDCDETNLRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 VPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 LSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 PLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 DLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQ
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 DLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSL-LEGIEISNIQQ
310 320 330 340 350
370 380 390 400 410 420
pF1KE9 RMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTC
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE9 FGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWM
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE9 ESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGF
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE9 IVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE9 SMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGT
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE9 ITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWV
660 670 680 690 700 710
730 740 750
pF1KE9 EMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
:::::::::::::::::::::::::::::::::::::
XP_016 EMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
720 730 740 750
>>XP_016864010 (OMIM: 606654) PREDICTED: relaxin recepto (676 aa)
initn: 4545 init1: 4545 opt: 4545 Z-score: 2579.8 bits: 487.9 E(85289): 5.9e-137
Smith-Waterman score: 4545; 100.0% identity (100.0% similar) in 676 aa overlap (82-757:1-676)
60 70 80 90 100 110
pF1KE9 DCGNQADEDNCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLEL
::::::::::::::::::::::::::::::
XP_016 MTSQYPFEAETPECLVGSVPVQCLCQGLEL
10 20 30
120 130 140 150 160 170
pF1KE9 DCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFR
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE9 GLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMN
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE9 NVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTF
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE9 APLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLE
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE9 GIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVF
280 290 300 310 320 330
420 430 440 450 460 470
pF1KE9 VWVVSAVTCFGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VWVVSAVTCFGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGE
340 350 360 370 380 390
480 490 500 510 520 530
pF1KE9 YNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITV
400 410 420 430 440 450
540 550 560 570 580 590
pF1KE9 LILIWITGFIVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LILIWITGFIVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAA
460 470 480 490 500 510
600 610 620 630 640 650
pF1KE9 FIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLS
520 530 540 550 560 570
660 670 680 690 700 710
pF1KE9 LLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQK
580 590 600 610 620 630
720 730 740 750
pF1KE9 TYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
640 650 660 670
>>XP_016864011 (OMIM: 606654) PREDICTED: relaxin recepto (675 aa)
initn: 4526 init1: 2750 opt: 4528 Z-score: 2570.3 bits: 486.1 E(85289): 2e-136
Smith-Waterman score: 4528; 99.9% identity (99.9% similar) in 676 aa overlap (82-757:1-675)
60 70 80 90 100 110
pF1KE9 DCGNQADEDNCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLEL
::::::::::::::::::::::::::::::
XP_016 MTSQYPFEAETPECLVGSVPVQCLCQGLEL
10 20 30
120 130 140 150 160 170
pF1KE9 DCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFR
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE9 GLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMN
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE9 NVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTF
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE9 APLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 APLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSL-LE
220 230 240 250 260
360 370 380 390 400 410
pF1KE9 GIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVF
270 280 290 300 310 320
420 430 440 450 460 470
pF1KE9 VWVVSAVTCFGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VWVVSAVTCFGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGE
330 340 350 360 370 380
480 490 500 510 520 530
pF1KE9 YNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITV
390 400 410 420 430 440
540 550 560 570 580 590
pF1KE9 LILIWITGFIVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LILIWITGFIVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAA
450 460 470 480 490 500
600 610 620 630 640 650
pF1KE9 FIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLS
510 520 530 540 550 560
660 670 680 690 700 710
pF1KE9 LLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQK
570 580 590 600 610 620
720 730 740 750
pF1KE9 TYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
630 640 650 660 670
>>NP_001240657 (OMIM: 606654) relaxin receptor 1 isoform (724 aa)
initn: 4460 init1: 4460 opt: 4460 Z-score: 2531.8 bits: 479.1 E(85289): 2.8e-134
Smith-Waterman score: 4828; 95.5% identity (95.6% similar) in 757 aa overlap (1-757:1-724)
10 20 30 40 50 60
pF1KE9 MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLELDCDETNLRA
: :.::::::::::::::::::::::::
NP_001 N---------------------------------CVVGSVPVQCLCQGLELDCDETNLRA
70 80
130 140 150 160 170 180
pF1KE9 VPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLY
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE9 LSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDK
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE9 PLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEL
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE9 DLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQ
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE9 RMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTC
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE9 FGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWM
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE9 ESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGF
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE9 IVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYG
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE9 SMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGT
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE9 ITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWV
630 640 650 660 670 680
730 740 750
pF1KE9 EMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
:::::::::::::::::::::::::::::::::::::
NP_001 EMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
690 700 710 720
>>XP_016864008 (OMIM: 606654) PREDICTED: relaxin recepto (703 aa)
initn: 4441 init1: 4441 opt: 4441 Z-score: 2521.3 bits: 477.1 E(85289): 1.1e-133
Smith-Waterman score: 4477; 96.0% identity (96.2% similar) in 703 aa overlap (82-757:1-703)
60 70 80 90
pF1KE9 DCGNQADEDNCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPEC----------------
::::::::::::::
XP_016 MTSQYPFEAETPECSFHFFLFITLLFLVPH
10 20 30
100 110 120 130 140
pF1KE9 -----------LVGSVPVQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPD
.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CHHALPLPLDSVVGSVPVQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPD
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE9 CFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLI
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE9 IEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRN
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE9 LTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQL
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE9 NLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAP
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE9 HVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLYAMSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLYAMSI
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE9 ISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLT
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE9 FLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGFIVAFIPLSNKEFFKNYYGTNGVCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGFIVAFIPLSNKEFFKNYYGTNGVCF
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE9 PLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEM
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE9 ILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLT
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE9 TRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEM
640 650 660 670 680 690
750
pF1KE9 SLISQSTRLNSYS
:::::::::::::
XP_016 SLISQSTRLNSYS
700
>>XP_016864009 (OMIM: 606654) PREDICTED: relaxin recepto (703 aa)
initn: 4441 init1: 4441 opt: 4441 Z-score: 2521.3 bits: 477.1 E(85289): 1.1e-133
Smith-Waterman score: 4477; 96.0% identity (96.2% similar) in 703 aa overlap (82-757:1-703)
60 70 80 90
pF1KE9 DCGNQADEDNCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPEC----------------
::::::::::::::
XP_016 MTSQYPFEAETPECSFHFFLFITLLFLVPH
10 20 30
100 110 120 130 140
pF1KE9 -----------LVGSVPVQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPD
.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CHHALPLPLDSVVGSVPVQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPD
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE9 CFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLI
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE9 IEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRN
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE9 LTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQL
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE9 NLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAP
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE9 HVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLYAMSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLYAMSI
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE9 ISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLT
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE9 FLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGFIVAFIPLSNKEFFKNYYGTNGVCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGFIVAFIPLSNKEFFKNYYGTNGVCF
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE9 PLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEM
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE9 ILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLT
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE9 TRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEM
640 650 660 670 680 690
750
pF1KE9 SLISQSTRLNSYS
:::::::::::::
XP_016 SLISQSTRLNSYS
700
>>NP_001240656 (OMIM: 606654) relaxin receptor 1 isoform (784 aa)
initn: 4441 init1: 4441 opt: 4441 Z-score: 2520.9 bits: 477.2 E(85289): 1.1e-133
Smith-Waterman score: 5081; 96.4% identity (96.6% similar) in 784 aa overlap (1-757:1-784)
10 20 30 40 50 60
pF1KE9 MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
10 20 30 40 50 60
70 80 90
pF1KE9 NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPEC-------------------------
:::::::::::::::::::::::::::::::::::
NP_001 NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECSFHFFLFITLLFLVPHCHHALPLPL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE9 --LVGSVPVQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQ
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSVVGSVPVQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQ
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE9 KLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRI
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE9 SPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE9 TVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQK
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE9 IQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNT
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE9 DGISSLENLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLYAMSIISLCCADCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGISSLENLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLYAMSIISLCCADCL
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE9 MGIYLFVIGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGIYLFVIGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYIC
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE9 IVYPFRCVRPGKCRTITVLILIWITGFIVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVYPFRCVRPGKCRTITVLILIWITGFIVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTES
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE9 IGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFI
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE9 VFTDALCWIPIFVVKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFTDALCWIPIFVVKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIH
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE9 RFWYNYRQRKSMDSKGQKTYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEMSLISQSTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFWYNYRQRKSMDSKGQKTYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEMSLISQSTRL
730 740 750 760 770 780
pF1KE9 NSYS
::::
NP_001 NSYS
>>XP_011530476 (OMIM: 606654) PREDICTED: relaxin recepto (783 aa)
initn: 4422 init1: 2750 opt: 4424 Z-score: 2511.3 bits: 475.4 E(85289): 3.8e-133
Smith-Waterman score: 5064; 96.3% identity (96.4% similar) in 784 aa overlap (1-757:1-783)
10 20 30 40 50 60
pF1KE9 MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED
10 20 30 40 50 60
70 80 90
pF1KE9 NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPEC-------------------------
:::::::::::::::::::::::::::::::::::
XP_011 NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECSFHFFLFITLLFLVPHCHHALPLPL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE9 --LVGSVPVQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQ
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSVVGSVPVQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQ
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE9 KLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRI
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE9 SPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE9 TVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQK
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE9 IQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNT
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQANQFDYLVKLKSL-LEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNT
370 380 390 400 410
400 410 420 430 440 450
pF1KE9 DGISSLENLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLYAMSIISLCCADCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGISSLENLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLYAMSIISLCCADCL
420 430 440 450 460 470
460 470 480 490 500 510
pF1KE9 MGIYLFVIGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGIYLFVIGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYIC
480 490 500 510 520 530
520 530 540 550 560 570
pF1KE9 IVYPFRCVRPGKCRTITVLILIWITGFIVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVYPFRCVRPGKCRTITVLILIWITGFIVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTES
540 550 560 570 580 590
580 590 600 610 620 630
pF1KE9 IGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFI
600 610 620 630 640 650
640 650 660 670 680 690
pF1KE9 VFTDALCWIPIFVVKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFTDALCWIPIFVVKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIH
660 670 680 690 700 710
700 710 720 730 740 750
pF1KE9 RFWYNYRQRKSMDSKGQKTYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEMSLISQSTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFWYNYRQRKSMDSKGQKTYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEMSLISQSTRL
720 730 740 750 760 770
pF1KE9 NSYS
::::
XP_011 NSYS
780
>>NP_001240659 (OMIM: 606654) relaxin receptor 1 isoform (626 aa)
initn: 4192 init1: 2750 opt: 4194 Z-score: 2383.1 bits: 451.4 E(85289): 5.3e-126
Smith-Waterman score: 4194; 99.8% identity (99.8% similar) in 627 aa overlap (131-757:1-626)
110 120 130 140 150 160
pF1KE9 PVQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNN
::::::::::::::::::::::::::::::
NP_001 MSLQWNLIRKLPPDCFKNYHDLQKLYLQNN
10 20 30
170 180 190 200 210 220
pF1KE9 KITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYG
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE9 LNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRK
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE9 NKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFD
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE9 YLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLE
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLVKLKSL-LEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLE
220 230 240 250 260
410 420 430 440 450 460
pF1KE9 NLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFV
270 280 290 300 310 320
470 480 490 500 510 520
pF1KE9 IGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRC
330 340 350 360 370 380
530 540 550 560 570 580
pF1KE9 VRPGKCRTITVLILIWITGFIVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRPGKCRTITVLILIWITGFIVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYS
390 400 410 420 430 440
590 600 610 620 630 640
pF1KE9 VAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALC
450 460 470 480 490 500
650 660 670 680 690 700
pF1KE9 WIPIFVVKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIPIFVVKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYR
510 520 530 540 550 560
710 720 730 740 750
pF1KE9 QRKSMDSKGQKTYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRKSMDSKGQKTYAPSFIWVEMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS
570 580 590 600 610 620
757 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 07:41:52 2016 done: Sun Nov 6 07:41:54 2016
Total Scan time: 9.040 Total Display time: 0.200
Function used was FASTA [36.3.4 Apr, 2011]