Result of FASTA (ccds) for
pFN21AE9536
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9536, 1215 aa
1>>>pF1KE9536 1215 - 1215 aa - 1215 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5768+/-0.00108; mu= 12.3174+/- 0.065
mean_var=130.1963+/-25.337, 0's: 0 Z-trim(107.7): 42 B-trim: 49 in 1/51
Lambda= 0.112402
statistics sampled from 9700 (9722) to 9700 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.299), width: 16
Scan time: 3.310
The best scores are: opt bits E(32554)
CCDS31166.1 GPR158 gene_id:57512|Hs108|chr10 (1215) 8144 1333.0 0
CCDS42308.1 GPR179 gene_id:440435|Hs108|chr17 (2367) 2035 342.5 7.4e-93
>>CCDS31166.1 GPR158 gene_id:57512|Hs108|chr10 (1215 aa)
initn: 8144 init1: 8144 opt: 8144 Z-score: 7138.8 bits: 1333.0 E(32554): 0
Smith-Waterman score: 8144; 99.9% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215)
10 20 30 40 50 60
pF1KE9 MGAMAYPLLLCLLLAQLGLGAVGASRDPQGRPDSPRERTPKGKPHAQQPGRASASDSSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MGAMAYPLLLCLLLAQLGLGAVGASRDPQGRPDSPRERTPKGKPHAQQPGRASASDSSAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 WSRSTDGTILAQKLAEEVPMDVASYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 WSRSTDGTILAQKLAEEVPMDVASYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 SLHRALDTLTHATNFLNVMLQSNKSREQNLQDDLDWYQALVWSLLEGEPSISRAAITFST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SLHRALDTLTHATNFLNVMLQSNKSREQNLQDDLDWYQALVWSLLEGEPSISRAAITFST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 DSLSAPAPQVFLQATREESRILLQDLSSSAPHLANATLETEWFHGLRRKWRPHLHRRGPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DSLSAPAPQVFLQATREESRILLQDLSSSAPHLANATLETEWFHGLRRKWRPHLHRRGPN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 QGPRGLGHSWRRKDGLGGDKSHFKWSPPYLECENGSYKPGWLVTLSSAIYGLQPNLVPEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 QGPRGLGHSWRRKDGLGGDKSHFKWSPPYLECENGSYKPGWLVTLSSAIYGLQPNLVPEF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 RGVMKVDINLQKVDIDQCSSDGWFSGTHKCHLNNSECMPIKGLGFVLGAYECICKAGFYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RGVMKVDINLQKVDIDQCSSDGWFSGTHKCHLNNSECMPIKGLGFVLGAYECICKAGFYH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 PGVLPVNNFRRRGPDQHISGSTKDVSEEAYVCLPCREGCPFCADDSPCFVQEDKYLRLAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 PGVLPVNNFRRRGPDQHISGSTKDVSEEAYVCLPCREGCPFCADDSPCFVQEDKYLRLAI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ISFQGLCMLLDFVSMLVVYHFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFR
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 ISFQALCMLLDFVSMLVVYHFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 CILLRWARLLGFATVYGTVTLKLHRVLKVFLSRTAQRIPYMTGGRVMRMLAVILLVVFWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 CILLRWARLLGFATVYGTVTLKLHRVLKVFLSRTAQRIPYMTGGRVMRMLAVILLVVFWF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 LIGWTSSVCQNLEKQISLIGQGKTSDHLIFNMCLIDRWDYMTAVAEFLFLLWGVYLCYAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LIGWTSSVCQNLEKQISLIGQGKTSDHLIFNMCLIDRWDYMTAVAEFLFLLWGVYLCYAV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 RTVPSAFHEPRYMAVAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RTVPSAFHEPRYMAVAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 LLLIPKFSHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LLLIPKFSHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 LYAQLEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LYAQLEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 TAKGTALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 TAKGTALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 EETTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EETTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 KSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 KSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 SNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 SESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 ILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENENLNQIGHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 ILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENENLNQIGHQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE9 EKKTSSSEENVRGSYNSSNNFQQPLTSRAEVCPWEFETPAQPNAGRSVALPASSALSANK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EKKTSSSEENVRGSYNSSNNFQQPLTSRAEVCPWEFETPAQPNAGRSVALPASSALSANK
1150 1160 1170 1180 1190 1200
1210
pF1KE9 IAGPRKEEIWDSFKV
:::::::::::::::
CCDS31 IAGPRKEEIWDSFKV
1210
>>CCDS42308.1 GPR179 gene_id:440435|Hs108|chr17 (2367 aa)
initn: 2134 init1: 1626 opt: 2035 Z-score: 1780.5 bits: 342.5 E(32554): 7.4e-93
Smith-Waterman score: 2451; 39.4% identity (64.3% similar) in 1157 aa overlap (77-1196:50-1144)
50 60 70 80 90 100
pF1KE9 QQPGRASASDSSAPWSRSTDGTILAQKLAEEVPMDVA----SYLYTGDSHQLKRANCSGR
.::.. : .:::.::..::...::: :
CCDS42 FVCAWALGGPRPIRSLPPLSSQVKPGSVPMQVPLEGAEAALAYLYSGDAQQLSQVNCSER
20 30 40 50 60 70
110 120 130 140 150 160
pF1KE9 YELAGLPGKWPALASAHPSLHRALDTLTHATNFLNVMLQSNKSREQNLQDDLDWYQALVW
:: : : :.: :::. : ::..:.::::..::.: ::.....:..::::::
CCDS42 YEARG-AGAMPGLP---PSLQGAAGTLAQAANFLNMLLQANDIRESSVEEDVEWYQALVR
80 90 100 110 120 130
170 180 190 200 210 220
pF1KE9 SLLEGEPSISRAAITFSTDSLSAPAPQVFLQATREESRILLQDLSSSAPHLANATLETEW
:. ::.: . :: .::. .: :. ::::: . .:::::.. . : . .
CCDS42 SVAEGDPRVYRALLTFNPPP-GASHLQLALQATRTGEETILQDLSGNWVQEENPPGDLD-
140 150 160 170 180 190
230 240 250 260 270 280
pF1KE9 FHGLRRKWRPHLHRRGPNQGPRGLGH-SWRRKDGLGGDKSHFKWSPPYLECENGSYKPGW
: :..: .. .:: .: . :: :: .. . :::.:::..: .:::
CCDS42 --------TPALKKRVLTNDLGSLGSPKWPQADGYVGDTQQVRLSPPFLECQEGRLRPGW
200 210 220 230 240
290 300 310 320 330 340
pF1KE9 LVTLSSAIYGLQPNLVPEFRGVMKVDINLQKVDIDQCSSD-GWFSGTHKCHLNNSECMPI
:.:::...:::.:.: :: :: ...:..::.:::.::.: ::.:.:: : ::...:.:.
CCDS42 LITLSATFYGLKPDLSPEVRGQVQMDVDLQSVDINQCASGPGWYSNTHLCDLNSTQCVPL
250 260 270 280 290 300
350 360 370 380 390
pF1KE9 KGLGFVLGAYECICKAGFY--HP-GVLPVNNFRRRGPDQHISGSTKDVSEEAYVCLPCRE
.. ::::: : : :. ::: : : : ..:. : : : . : . :::: :
CCDS42 ESQGFVLGRYLCRCRPGFYGASPSGGLEESDFQTTG--QF--GFPEGRSGRLLQCLPCPE
310 320 330 340 350 360
400 410 420 430 440 450
pF1KE9 GCPFCADDSPCFVQEDKYLRLAIISFQGLCMLLDFVSMLVVYHFRKAKSIRASGLILLET
:: : : .::.:.: :: :... :. ::: :.:::: :. :. : : :::..::::
CCDS42 GCTSCMDATPCLVEEAAVLRAAVLACQACCMLAIFLSMLVSYRCRRNKRIWASGVVLLET
370 380 390 400 410 420
460 470 480 490 500 510
pF1KE9 ILFGSLLLYFPVVILYFEPSTFRCILLRWARLLGFATVYGTVTLKLHRVLKVFLSRTAQR
.::: ::::::: ::::.::.:::: :::.:::::: ::::. :::.:::..::::::::
CCDS42 VLFGFLLLYFPVFILYFKPSVFRCIALRWVRLLGFAIVYGTIILKLYRVLQLFLSRTAQR
430 440 450 460 470 480
520 530 540 550 560 570
pF1KE9 IPYMTGGRVMRMLAVILLVVFWFLIGWTSSVCQNLEKQISLIGQGKTSDHLIFNMCLIDR
...::..: :...:: :. :: :: .. . .. :. .:.: . : .: ::
CCDS42 SALLSSGRLLRHLGLLLLPVLGFLAVWTVGALERGIQHAPLVIRGHTPSGRHFYLCHHDR
490 500 510 520 530 540
580 590 600 610 620 630
pF1KE9 WDYMTAVAEFLFLLWGVYLCYAVRTVPSAFHEPRYMAVAVHNELIISAIFHTIRFVLASR
:::. .:::.:.: :: .::::.:.: :::::::::..:.::::..:: ::: ::::.
CCDS42 WDYIMVVAELLLLCWGSFLCYATRAVLSAFHEPRYMGIALHNELLLSAAFHTARFVLVPS
550 560 570 580 590 600
640 650 660 670 680 690
pF1KE9 LQSDWMLMLYFAHTHLTVTVTIGLLLIPKFSHSSNNPRDDIATEAYEDELDMGRSGSYLN
:. :: :.:.: ::: :::.:..:..:::: . . ::.... :. :::::. .:::::.
CCDS42 LHPDWTLLLFFFHTHSTVTTTLALIFIPKFWKLGAPPREEMVDEVCEDELDLQHSGSYLG
610 620 630 640 650 660
700 710 720 730 740 750
pF1KE9 SSINSAWSEHSLDPEDIRDELKKLYAQLEIYKRKKMITNNPHLQKKRCSK-KGLGRSIMR
::: :::::::::: ::::::::::::::..: :.: .::::: ::: :. .:::::.::
CCDS42 SSIASAWSEHSLDPGDIRDELKKLYAQLEVHKTKEMAANNPHLPKKRGSSCQGLGRSFMR
670 680 690 700 710 720
760 770 780 790 800 810
pF1KE9 RITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPPESSGNTGKSKEETLKNRVFSLKK
..:.::...:: :. :. . ::. :.. :. :: . .. .:.:
CCDS42 YLAEFPEALARQHSR-DSGSPGHGSLPGSS--RRRLLSSSLQEPEGTP--------ALHK
730 740 750 760 770
820 830 840 850 860 870
pF1KE9 SHSTYDHVRDQTEESSSLPTESQEEETTENSTLESLSGKKLTQKLKEDSEAESTESVP-L
:.::::. :.: . :.:: .::..: .. ::.:. : :
CCDS42 SRSTYDQRREQ-----------------DPPLLDSLLRRKLAKKASRTESRESVEGPPAL
780 790 800 810
880 890 900 910 920
pF1KE9 VCKSASAHNLSSEKKTGHPRTSMLQKSLSVIASAKEKTLGLAGKT-------QTAGVEER
.:::::::. .. . : . ::::::: ::..::.: .:... :. :::
CCDS42 GFRSASAHNLTVGERLPRARPASLQKSLSV-ASSREKALLMASQAYLEETYRQAKEREER
820 830 840 850 860 870
930 940 950 960 970
pF1KE9 TKSQKPLP---KDKETNRNHSNSDNTETKDPAPQNSNPA----------EEPRKPQKSGI
:.. . . . : . . :.: .:. . :: :.
CCDS42 KKAKAAMASLVRRPSARRLERPRGAPLSAPPSPAKSSSVDSSHTSGRLHEEARRRLPHPP
880 890 900 910 920 930
980 990 1000 1010 1020 1030
pF1KE9 MKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESKV--QKHVSIVA
...: .: : :. : . . . . : . :.: :.:. . : . . .
CCDS42 IRHQVSTPILA---LSGGLGEPRMLSPTSTLAPALLPALAPTPAPALAPVPVSPQSPNLL
940 950 960 970 980
1040 1050 1060 1070 1080 1090
pF1KE9 SEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQSILEDEKLLISKTP
. . . : :... :. . . ... :.. ::.. . . . :.
CCDS42 TYICPWENAELPAKQENVPQEGPSGPERGHHSPAPARARLWRALS--------VAVEKSR
990 1000 1010 1020 1030 1040
1100 1110 1120 1130 1140 1150
pF1KE9 VLPERAKEENGGQPRAANVCAGQSEELPPKAVASKT--ENENLNQIGHQEKKTSSSEENV
. .. :.. . : :: . .. ::. . :. .. .. ..: : . :
CCDS42 AGENEMDAEDAHHQREANDVDEDRPKIFPKSHSLKAPVQQGSMRSLGLAIKALTRS----
1050 1060 1070 1080 1090
1160 1170 1180 1190 1200
pF1KE9 RGSYNSSNNFQQ-PLTSRAEVCPWEFETPAQ-PNAGRSVALPASSALSANKIAGPRKEEI
:..: ... .. : . . . . .:.. : :: :. ..::
CCDS42 RSTYREKESVEESPEGQNSGTAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQQ
1100 1110 1120 1130 1140 1150
1210
pF1KE9 WDSFKV
CCDS42 NAHTSRMLQVCQREGSREQEDRGRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSKE
1160 1170 1180 1190 1200 1210
1215 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:45:38 2016 done: Mon Nov 7 18:45:38 2016
Total Scan time: 3.310 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]