Result of FASTA (omim) for
pFN21AE9526
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9526, 438 aa
1>>>pF1KE9526 438 - 438 aa - 438 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9767+/-0.000378; mu= 19.3932+/- 0.023
mean_var=73.5460+/-15.244, 0's: 0 Z-trim(113.9): 238 B-trim: 331 in 1/48
Lambda= 0.149553
statistics sampled from 23227 (23522) to 23227 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.276), width: 16
Scan time: 6.810
The best scores are: opt bits E(85289)
NP_003373 (OMIM: 601970) vasoactive intestinal pol ( 438) 3008 658.5 9.5e-189
XP_005249618 (OMIM: 601970) PREDICTED: vasoactive ( 463) 2887 632.4 7.1e-181
XP_006716170 (OMIM: 601970) PREDICTED: vasoactive ( 455) 2624 575.7 8.5e-164
NP_001295188 (OMIM: 601970) vasoactive intestinal ( 422) 2156 474.7 2e-133
XP_016868069 (OMIM: 601970) PREDICTED: vasoactive ( 300) 2040 449.5 5.3e-126
XP_006716171 (OMIM: 601970) PREDICTED: vasoactive ( 392) 2016 444.5 2.4e-124
XP_011514852 (OMIM: 601970) PREDICTED: vasoactive ( 439) 1772 391.9 1.8e-108
NP_001291451 (OMIM: 601970) vasoactive intestinal ( 358) 1634 362.0 1.4e-99
NP_001186566 (OMIM: 102981) pituitary adenylate cy ( 447) 1513 336.0 1.2e-91
NP_004615 (OMIM: 192321) vasoactive intestinal pol ( 457) 1359 302.8 1.2e-81
NP_001238814 (OMIM: 192321) vasoactive intestinal ( 430) 1349 300.6 5.3e-81
XP_005265494 (OMIM: 192321) PREDICTED: vasoactive ( 456) 1348 300.4 6.4e-81
NP_001238811 (OMIM: 192321) vasoactive intestinal ( 416) 1335 297.5 4.2e-80
XP_011532381 (OMIM: 192321) PREDICTED: vasoactive ( 416) 1335 297.5 4.2e-80
XP_005265495 (OMIM: 192321) PREDICTED: vasoactive ( 416) 1335 297.5 4.2e-80
XP_005249675 (OMIM: 102981) PREDICTED: pituitary a ( 411) 1334 297.3 4.8e-80
NP_001109 (OMIM: 102981) pituitary adenylate cycla ( 468) 1334 297.4 5.3e-80
NP_002971 (OMIM: 182098) secretin receptor precurs ( 440) 1328 296.1 1.2e-79
XP_005265496 (OMIM: 192321) PREDICTED: vasoactive ( 410) 1324 295.2 2.1e-79
NP_001238813 (OMIM: 192321) vasoactive intestinal ( 409) 1313 292.8 1.1e-78
XP_016860159 (OMIM: 182098) PREDICTED: secretin re ( 435) 1269 283.3 8.4e-76
XP_011509923 (OMIM: 182098) PREDICTED: secretin re ( 445) 1269 283.3 8.5e-76
XP_016860161 (OMIM: 182098) PREDICTED: secretin re ( 377) 1249 279.0 1.5e-74
XP_016867226 (OMIM: 102981) PREDICTED: pituitary a ( 475) 1166 261.1 4.4e-69
NP_000814 (OMIM: 139191,612781) growth hormone-rel ( 423) 1165 260.9 4.7e-69
XP_016860160 (OMIM: 182098) PREDICTED: secretin re ( 409) 1146 256.8 7.8e-68
XP_011532382 (OMIM: 192321) PREDICTED: vasoactive ( 351) 1028 231.2 3.2e-60
XP_016867227 (OMIM: 102981) PREDICTED: pituitary a ( 439) 987 222.5 1.7e-57
XP_016867225 (OMIM: 102981) PREDICTED: pituitary a ( 489) 987 222.5 1.9e-57
NP_001186565 (OMIM: 102981) pituitary adenylate cy ( 495) 987 222.5 1.9e-57
XP_006715708 (OMIM: 102981) PREDICTED: pituitary a ( 496) 987 222.5 1.9e-57
NP_001186564 (OMIM: 102981) pituitary adenylate cy ( 496) 987 222.5 1.9e-57
XP_011513565 (OMIM: 139191,612781) PREDICTED: grow ( 359) 955 215.5 1.8e-55
XP_005263787 (OMIM: 182098) PREDICTED: secretin re ( 262) 893 202.0 1.5e-51
NP_000155 (OMIM: 137241) gastric inhibitory polype ( 466) 887 200.9 5.7e-51
XP_016860162 (OMIM: 182098) PREDICTED: secretin re ( 267) 873 197.7 3.1e-50
NP_001295347 (OMIM: 137241) gastric inhibitory pol ( 430) 819 186.2 1.4e-46
XP_016879936 (OMIM: 125853,138033) PREDICTED: gluc ( 355) 814 185.1 2.6e-46
XP_011521841 (OMIM: 125853,138033) PREDICTED: gluc ( 444) 814 185.2 3e-46
XP_016879935 (OMIM: 125853,138033) PREDICTED: gluc ( 475) 814 185.2 3.2e-46
XP_006722340 (OMIM: 125853,138033) PREDICTED: gluc ( 477) 814 185.2 3.2e-46
NP_000151 (OMIM: 125853,138033) glucagon receptor ( 477) 814 185.2 3.2e-46
NP_004237 (OMIM: 603659) glucagon-like peptide 2 r ( 553) 769 175.5 3e-43
XP_016880828 (OMIM: 603659) PREDICTED: glucagon-li ( 559) 769 175.5 3e-43
XP_011522379 (OMIM: 603659) PREDICTED: glucagon-li ( 578) 769 175.5 3.1e-43
XP_005256918 (OMIM: 603659) PREDICTED: glucagon-li ( 400) 766 174.8 3.7e-43
XP_016880830 (OMIM: 603659) PREDICTED: glucagon-li ( 448) 766 174.8 4e-43
XP_016880829 (OMIM: 603659) PREDICTED: glucagon-li ( 483) 766 174.8 4.2e-43
NP_002053 (OMIM: 138032) glucagon-like peptide 1 r ( 463) 732 167.5 6.6e-41
XP_016866239 (OMIM: 138032) PREDICTED: glucagon-li ( 468) 732 167.5 6.7e-41
>>NP_003373 (OMIM: 601970) vasoactive intestinal polypep (438 aa)
initn: 3008 init1: 3008 opt: 3008 Z-score: 3509.6 bits: 658.5 E(85289): 9.5e-189
Smith-Waterman score: 3008; 100.0% identity (100.0% similar) in 438 aa overlap (1-438:1-438)
10 20 30 40 50 60
pF1KE9 MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNIT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 CWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 DVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 FLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 SIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 LCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSRNGSEGALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSRNGSEGALQ
370 380 390 400 410 420
430
pF1KE9 FHRGSRAQSFLQTETSVI
::::::::::::::::::
NP_003 FHRGSRAQSFLQTETSVI
430
>>XP_005249618 (OMIM: 601970) PREDICTED: vasoactive inte (463 aa)
initn: 2886 init1: 2886 opt: 2887 Z-score: 3368.2 bits: 632.4 E(85289): 7.1e-181
Smith-Waterman score: 2887; 98.2% identity (98.6% similar) in 434 aa overlap (5-438:35-463)
10 20 30
pF1KE9 MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEE
: :.: .:: :::::::::::::::::
XP_005 GAVPGAGSCGRLRGLRVSRGDRGWRWPQMPLGPSL---YLL--VNSIHPECRFHLEIQEE
10 20 30 40 50
40 50 60 70 80 90
pF1KE9 ETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCT
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE9 SDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKL
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE9 HCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIM
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE9 ANFFWLLVEGLYLHTLLVAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANFFWLLVEGLYLHTLLVAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDT
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 NDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLI
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE9 PLFGVHYMVFAVFPISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLFGVHYMVFAVFPISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRC
360 370 380 390 400 410
400 410 420 430
pF1KE9 PTPSASRDYRVCGSSFSRNGSEGALQFHRGSRAQSFLQTETSVI
::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTPSASRDYRVCGSSFSRNGSEGALQFHRGSRAQSFLQTETSVI
420 430 440 450 460
>>XP_006716170 (OMIM: 601970) PREDICTED: vasoactive inte (455 aa)
initn: 2621 init1: 2621 opt: 2624 Z-score: 3061.7 bits: 575.7 E(85289): 8.5e-164
Smith-Waterman score: 2624; 93.5% identity (95.0% similar) in 417 aa overlap (1-409:1-414)
10 20 30 40 50 60
pF1KE9 MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNIT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 CWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 TFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 DVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 FLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 SIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFE
310 320 330 340 350 360
370 380 390 400 410
pF1KE9 LCLGSFQGLVVAVLYCFLNSEVQCELKRKWRS--------RCPTPSASRDYRVCGSSFSR
::::::::::::::::::::::. : . :: :. :. ..: ::
XP_006 LCLGSFQGLVVAVLYCFLNSEVSS--WPPWNQAQVLTCFLRC-CPAWCRSPHTCLSSAGS
370 380 390 400 410
420 430
pF1KE9 NGSEGALQFHRGSRAQSFLQTETSVI
XP_006 SYCPGPHSSVSPSENPQRHRQTHSSGPSFQTPPSFRPP
420 430 440 450
>>NP_001295188 (OMIM: 601970) vasoactive intestinal poly (422 aa)
initn: 2152 init1: 2152 opt: 2156 Z-score: 2516.4 bits: 474.7 E(85289): 2e-133
Smith-Waterman score: 2156; 93.7% identity (95.4% similar) in 347 aa overlap (92-438:80-422)
70 80 90 100 110 120
pF1KE9 WRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKIT
: : . .: . .:. . :: ::
NP_001 SEGSLPSWSSGPAGAKLNASHEGIGSSSDGNGDSKAATERVVSAMDTVRRKHPE----IT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE9 FYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE9 VLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCF
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 LAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFIS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE9 IIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFEL
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE9 CLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSRNGSEGALQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSRNGSEGALQF
350 360 370 380 390 400
430
pF1KE9 HRGSRAQSFLQTETSVI
:::::::::::::::::
NP_001 HRGSRAQSFLQTETSVI
410 420
>>XP_016868069 (OMIM: 601970) PREDICTED: vasoactive inte (300 aa)
initn: 2040 init1: 2040 opt: 2040 Z-score: 2383.1 bits: 449.5 E(85289): 5.3e-126
Smith-Waterman score: 2040; 100.0% identity (100.0% similar) in 300 aa overlap (139-438:1-300)
110 120 130 140 150 160
pF1KE9 CGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLS
::::::::::::::::::::::::::::::
XP_016 MSLATGSIILCLFRKLHCTRNYIHLNLFLS
10 20 30
170 180 190 200 210 220
pF1KE9 FILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLH
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE9 TLLVAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLVAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPI
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE9 LISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFP
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE9 ISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGS
220 230 240 250 260 270
410 420 430
pF1KE9 SFSRNGSEGALQFHRGSRAQSFLQTETSVI
::::::::::::::::::::::::::::::
XP_016 SFSRNGSEGALQFHRGSRAQSFLQTETSVI
280 290 300
>>XP_006716171 (OMIM: 601970) PREDICTED: vasoactive inte (392 aa)
initn: 2007 init1: 2007 opt: 2016 Z-score: 2353.6 bits: 444.5 E(85289): 2.4e-124
Smith-Waterman score: 2016; 90.5% identity (92.9% similar) in 337 aa overlap (81-409:18-351)
60 70 80 90 100 110
pF1KE9 ACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACG
:. . ::::::::::::::::::::::::
XP_006 MVAEPKSLLRIFILPQKNYTYSCGNISKNCTSDGWSETFPDFVDACG
10 20 30 40
120 130 140 150 160 170
pF1KE9 YSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFI
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE9 LRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTL
110 120 130 140 150 160
240 250 260 270 280 290
pF1KE9 LVAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILI
170 180 190 200 210 220
300 310 320 330 340 350
pF1KE9 SIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPIS
230 240 250 260 270 280
360 370 380 390 400
pF1KE9 ISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRS--------RCPTPSASRD
::::::::::::::::::::::::::::::::. : . :: :. :.
XP_006 ISSKYQILFELCLGSFQGLVVAVLYCFLNSEVSSW--PPWNQAQVLTCFLRC-CPAWCRS
290 300 310 320 330 340
410 420 430
pF1KE9 YRVCGSSFSRNGSEGALQFHRGSRAQSFLQTETSVI
..: ::
XP_006 PHTCLSSAGSSYCPGPHSSVSPSENPQRHRQTHSSGPSFQTPPSFRPP
350 360 370 380 390
>>XP_011514852 (OMIM: 601970) PREDICTED: vasoactive inte (439 aa)
initn: 1765 init1: 1765 opt: 1772 Z-score: 2068.4 bits: 391.9 E(85289): 1.8e-108
Smith-Waterman score: 1772; 85.0% identity (88.7% similar) in 326 aa overlap (92-409:80-398)
70 80 90 100 110 120
pF1KE9 WRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKIT
: : . .: . .:. . :: ::
XP_011 SEGSLPSWSSGPAGAKLNASHEGIGSSSDGNGDSKAATERVVSAMDTVRRKHPE----IT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE9 FYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE9 VLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCF
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 LAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFIS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE9 IIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFEL
290 300 310 320 330 340
370 380 390 400 410
pF1KE9 CLGSFQGLVVAVLYCFLNSEVQCELKRKWRS--------RCPTPSASRDYRVCGSSFSRN
:::::::::::::::::::::. : . :: :. :. ..: ::
XP_011 CLGSFQGLVVAVLYCFLNSEVSS--WPPWNQAQVLTCFLRC-CPAWCRSPHTCLSSAGSS
350 360 370 380 390 400
420 430
pF1KE9 GSEGALQFHRGSRAQSFLQTETSVI
XP_011 YCPGPHSSVSPSENPQRHRQTHSSGPSFQTPPSFRPP
410 420 430
>>NP_001291451 (OMIM: 601970) vasoactive intestinal poly (358 aa)
initn: 1653 init1: 1632 opt: 1634 Z-score: 1908.6 bits: 362.0 E(85289): 1.4e-99
Smith-Waterman score: 2317; 81.7% identity (81.7% similar) in 438 aa overlap (1-438:1-358)
10 20 30 40 50 60
pF1KE9 MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNIT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 CWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESK-
70 80 90 100 110
130 140 150 160 170 180
pF1KE9 TFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKD
NP_001 ------------------------------------------------------------
190 200 210 220 230 240
pF1KE9 DVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRC
:::::::::::::::::::::::::::::::::::::::::
NP_001 -------------------VGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRC
120 130 140 150 160
250 260 270 280 290 300
pF1KE9 FLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFI
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE9 SIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFE
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE9 LCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSRNGSEGALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSRNGSEGALQ
290 300 310 320 330 340
430
pF1KE9 FHRGSRAQSFLQTETSVI
::::::::::::::::::
NP_001 FHRGSRAQSFLQTETSVI
350
>>NP_001186566 (OMIM: 102981) pituitary adenylate cyclas (447 aa)
initn: 966 init1: 809 opt: 1513 Z-score: 1766.3 bits: 336.0 E(85289): 1.2e-91
Smith-Waterman score: 1513; 52.3% identity (76.9% similar) in 428 aa overlap (10-429:9-433)
10 20 30 40 50
pF1KE9 MRTLLPPALLTCWLLAPVN-SIHPECRFHLE--IQEEETKCAELLRSQTEKHKACSGVWD
:. :: :. ..: .: :. : . :. . :. : . ... .: :.::
NP_001 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWD
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 NITCWRPANVGETVTVPCPKVFSNFY--SKAGNISKNCTSDGWSETFPDFVDACGYSDPE
:::::.::.::: : : ::..: : . : .:.::: ::::: :: . ::::... :
NP_001 NITCWKPAHVGEMVLVSCPELFRIFNPDQDMGVVSRNCTEDGWSEPFPHYFDACGFDEYE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 DES--KITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRA
.:. . .:. :::.::.:::.::..:.:. .::: :::::::::.::.:::.::.:::
NP_001 SETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 ISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLV-
:::..:: .::. . . :: : : :: .::..::...:.:::..::::: ::::
NP_001 ISVFIKDWILYAEQDSNHC---FISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 AMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISI
...: :: : : .:::: ::::. .:.. :::..:::::: :: .. ::::. :.. ::
NP_001 TFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 IVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISIS
.:::::::.:: ::.::: :::.:::..: : :::.::::::::::.:: ::: : ..:
NP_001 MVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVS
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE9 SKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSR
.. ...::: ::::::.::::::::::.::: :.:::::: . . :.. :..
NP_001 KRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLAS
360 370 380 390 400 410
420 430
pF1KE9 NGSEGALQFHRGSRAQSFLQTETSVI
.: .:. :. :...:
NP_001 SGVNGGTQLSILSKSSSQIRMSGLPADNLAT
420 430 440
>>NP_004615 (OMIM: 192321) vasoactive intestinal polypep (457 aa)
initn: 1111 init1: 652 opt: 1359 Z-score: 1586.6 bits: 302.8 E(85289): 1.2e-81
Smith-Waterman score: 1361; 46.9% identity (71.3% similar) in 463 aa overlap (1-438:1-457)
10 20 30 40
pF1KE9 MRTLLP-PALLTC-------WLLAPVNS----IHPECRFHLEIQEEETKCAELLRSQTEK
:: : :: : : :.:... .. :: . :. .. .: : ..: :.
NP_004 MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLE--EAQLEN
10 20 30 40 50
50 60 70 80 90 100
pF1KE9 HK-ACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAG-NISKNCTSDGWSETFPD-F
. .:: .:::.::: . :..:.. :: .:. : : : :.:..::..::.. : .
NP_004 ETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPY
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE9 VDACGYSDPE---DESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIH
::: .: ::.. :: ::. ::.::..:: .: ... :: :::::::::::::
NP_004 PIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE9 LNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLV
..::.:::::: .:..:: .:..:. . .: . :::: ..::.:::.:::::::::
NP_004 MHLFISFILRAAAVFIKDLALFDSGESDQCSEGS---VGCKAAMVFFQYCVMANFFWLLV
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE9 EGLYLHTLL-VAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPW
:::::.::: :... :. : .:.:::::.:.. .:: ::...:: ::::: . :. :
NP_004 EGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSL-W
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE9 WVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHY
:.:. ::: ::.:::.::: ::::::::: ::. .:.: :.:::.:::::::::::::
NP_004 WIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHY
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE9 MVFAVFPISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASR
..:: :: ... . ...::: .:::::.:::.::::::.::: ::.:::: .
NP_004 IMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGW
360 370 380 390 400 410
410 420 430
pF1KE9 DYRVCGSSFSRNGSEGALQFHR------GSRAQSFLQTETSVI
. . : . ::. . : :.: .: .:.:.:..
NP_004 NPKYRHPSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV
420 430 440 450
438 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:55:50 2016 done: Mon Nov 7 01:55:51 2016
Total Scan time: 6.810 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]