Result of FASTA (omim) for
pFN21AE9525
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9525, 364 aa
1>>>pF1KE9525 364 - 364 aa - 364 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.0264+/-0.000398; mu= 24.3970+/- 0.025
mean_var=106.9403+/-28.569, 0's: 0 Z-trim(112.3): 515 B-trim: 2194 in 2/50
Lambda= 0.124023
statistics sampled from 20507 (21242) to 20507 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.249), width: 16
Scan time: 6.830
The best scores are: opt bits E(85289)
NP_064445 (OMIM: 300822,303700,303900) long-wave-s ( 364) 2482 455.3 9.6e-128
NP_000504 (OMIM: 300821,303700,303800) medium-wave ( 364) 2419 444.1 2.4e-124
NP_001699 (OMIM: 190900,613522) short-wave-sensiti ( 348) 1027 195.0 2.2e-49
NP_000530 (OMIM: 136880,180380,610445,613731) rhod ( 348) 990 188.3 2.2e-47
NP_055137 (OMIM: 606695) opsin-3 [Homo sapiens] ( 402) 527 105.6 2e-22
NP_006574 (OMIM: 605224) visual pigment-like recep ( 337) 500 100.6 5.3e-21
NP_859528 (OMIM: 609042) opsin-5 [Homo sapiens] ( 354) 436 89.2 1.5e-17
XP_016865905 (OMIM: 609042) PREDICTED: opsin-5 iso ( 408) 436 89.3 1.6e-17
XP_016865900 (OMIM: 609042) PREDICTED: opsin-5 iso ( 298) 405 83.6 6.5e-16
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 371 77.8 5.6e-14
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 371 77.9 5.8e-14
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin ( 405) 354 74.7 4.2e-13
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489) 354 74.8 4.6e-13
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin ( 539) 354 74.9 4.9e-13
NP_005949 (OMIM: 600665) melatonin receptor type 1 ( 350) 345 72.9 1.2e-12
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 339 72.0 2.7e-12
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465) 331 70.6 7.8e-12
NP_004215 (OMIM: 300207) melatonin-related recepto ( 617) 325 69.8 1.9e-11
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 323 69.1 1.9e-11
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 323 69.1 2e-11
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407) 319 68.4 3.2e-11
XP_016865902 (OMIM: 609042) PREDICTED: opsin-5 iso ( 285) 317 67.8 3.5e-11
XP_016865901 (OMIM: 609042) PREDICTED: opsin-5 iso ( 285) 317 67.8 3.5e-11
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 316 67.8 4.6e-11
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 316 67.8 4.6e-11
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 316 67.8 4.7e-11
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 316 67.8 4.7e-11
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 316 67.9 4.7e-11
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 316 67.9 4.7e-11
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 316 67.9 4.8e-11
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 316 67.9 4.8e-11
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 316 67.9 4.8e-11
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 316 67.9 4.9e-11
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 316 68.0 5.2e-11
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 316 68.0 5.2e-11
NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 313 67.2 6.5e-11
NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 313 67.2 6.5e-11
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 309 66.5 1.1e-10
XP_011541141 (OMIM: 125853,600804) PREDICTED: mela ( 362) 308 66.3 1.2e-10
NP_005950 (OMIM: 125853,600804) melatonin receptor ( 362) 308 66.3 1.2e-10
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 307 66.2 1.4e-10
NP_056542 (OMIM: 162323) substance-P receptor isof ( 311) 305 65.7 1.6e-10
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 300 64.9 3.2e-10
XP_016874309 (OMIM: 602351) PREDICTED: chemokine-l ( 371) 298 64.6 4.2e-10
NP_004063 (OMIM: 602351) chemokine-like receptor 1 ( 371) 298 64.6 4.2e-10
NP_001135815 (OMIM: 602351) chemokine-like recepto ( 373) 298 64.6 4.2e-10
NP_001135817 (OMIM: 602351) chemokine-like recepto ( 373) 298 64.6 4.2e-10
NP_001135816 (OMIM: 602351) chemokine-like recepto ( 373) 298 64.6 4.2e-10
NP_115940 (OMIM: 176400,604161,614837) kiSS-1 rece ( 398) 298 64.6 4.3e-10
XP_016865898 (OMIM: 609042) PREDICTED: opsin-5 iso ( 303) 296 64.1 4.9e-10
>>NP_064445 (OMIM: 300822,303700,303900) long-wave-sensi (364 aa)
initn: 2482 init1: 2482 opt: 2482 Z-score: 2414.4 bits: 455.3 E(85289): 9.6e-128
Smith-Waterman score: 2482; 99.5% identity (100.0% similar) in 364 aa overlap (1-364:1-364)
10 20 30 40 50 60
pF1KE9 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 IFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 IFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWS
::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::.
NP_064 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 PLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS
310 320 330 340 350 360
pF1KE9 VSPA
::::
NP_064 VSPA
>>NP_000504 (OMIM: 300821,303700,303800) medium-wave-sen (364 aa)
initn: 2419 init1: 2419 opt: 2419 Z-score: 2353.5 bits: 444.1 E(85289): 2.4e-124
Smith-Waterman score: 2419; 95.9% identity (98.6% similar) in 364 aa overlap (1-364:1-364)
10 20 30 40 50 60
pF1KE9 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 IFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFV
:::: :::::::::::::::::::::::::::::::::::::::::::::.:::: ::::
NP_000 IFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWS
::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::.
NP_000 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVRFDAKLAIVGIAFSWIWA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYL
::::::::::::::::::::::::::::::::::::::::::::::::: ::.::.::::
NP_000 AVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFH
:::::::::::::::::::::::::::::::::..:.: :::::.:::::::::::: ::
NP_000 QVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGYPFH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 PLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSS
310 320 330 340 350 360
pF1KE9 VSPA
::::
NP_000 VSPA
>>NP_001699 (OMIM: 190900,613522) short-wave-sensitive o (348 aa)
initn: 1047 init1: 957 opt: 1027 Z-score: 1007.6 bits: 195.0 E(85289): 2.2e-49
Smith-Waterman score: 1027; 43.2% identity (75.7% similar) in 345 aa overlap (23-363:5-347)
10 20 30 40 50 60
pF1KE9 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWM
.. .. . : .:. ::..::.::::: :...: ...:
NP_001 MRKMSEEEFYLFKNISSV-GPWDGPQYHIAPVWAFYLQAAFM
10 20 30 40
70 80 90 100 110 120
pF1KE9 IFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFV
: . :..::.::...::::.:::.::::.. . . ... .: . .::::
NP_001 GTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASCNGYFV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE9 LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWS
.:. .:.:::. .. :.. ::::....::..:.:::::: ::..: :.. . .: .
NP_001 FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHALTVVLATWTIG
110 120 130 140 150 160
190 200 210 220 230
pF1KE9 AVWTAPPIFGWSRYWPHGLKTSCGPDVFS-GSSYPGVQSYMIVLMVTCCIIPLAIIMLCY
. ::.:::::. :.::. ::::: .. :..: . .:: :.. : :.::..: . :
NP_001 IGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRS-ESYTWFLFIFCFIVPLSLICFSY
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE9 LQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAF
:. :..::: ::.:: .:::::.::.::::::. ..:::. ::. :: . . : ....
NP_001 TQLLRALKAVAAQQQESATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHGL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE9 HPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF-GKKVDDGSELSSASKTEVSSV
....:..:.::: ::::.:: :::.::. ::... :: . : :. :..:::::.:
NP_001 DLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVCGKAMTDESDTCSSQKTEVSTV
290 300 310 320 330 340
360
pF1KE9 SS--VSPA
:: :.:
NP_001 SSTQVGPN
>>NP_000530 (OMIM: 136880,180380,610445,613731) rhodopsi (348 aa)
initn: 965 init1: 965 opt: 990 Z-score: 971.8 bits: 188.3 E(85289): 2.2e-47
Smith-Waterman score: 990; 43.2% identity (74.5% similar) in 345 aa overlap (21-359:2-346)
10 20 30 40 50
pF1KE9 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTYTNSNST---RGPFEGPNYHIAPRWVYHLTS
..:.. : ::.: :.::: :.:..: : . . .
NP_000 MNGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLA
10 20 30 40
60 70 80 90 100 110
pF1KE9 VWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSG
..:..... . : :.: .:.. :::: :::.::.::::::: .. . : .. ... :
NP_000 AYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE9 YFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSW
:::.: : :::. ..: : .::::.... ::..:::::..: :: . ::.:.::.:
NP_000 YFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTW
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE9 IWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIML
. . . .:::. ::::: :.::. ::: : .. . . .:..: ..:. ::. ::..
NP_000 VMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFF
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE9 CYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGY
:: :. .... .: ::.:: .::::::::::::..:..:. .:: ::. : . .. :
NP_000 CYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQGS
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE9 AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF--GKK-VDDGSELSSASKTE
: :.. ..::.:::::.:::::::..::.:::::.: . ::. . : ...::::
NP_000 NFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTTICCGKNPLGDDEASATVSKTE
290 300 310 320 330 340
360
pF1KE9 VSSVSSVSPA
.:.:.
NP_000 TSQVAPA
>>NP_055137 (OMIM: 606695) opsin-3 [Homo sapiens] (402 aa)
initn: 541 init1: 233 opt: 527 Z-score: 523.5 bits: 105.6 E(85289): 2e-22
Smith-Waterman score: 527; 31.8% identity (64.0% similar) in 311 aa overlap (38-337:23-324)
10 20 30 40 50 60
pF1KE9 QRLAGRHPQDSYEDSTQSSIFTYTNSNSTRGPFEGPNYHIAPRW---VYHLTSVWMIFVV
:: . . :: . .:. .. . .
NP_055 MYSGNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIG
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 TASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHP
.: .: :::. .::..:: : . .:::....:: .... :...:. . . .:
NP_055 LLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 MCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWSAVWT
:: .:.. :: ::... .:.....::.. : . . :. : .:.. :..: .:.
NP_055 GCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHAR-VINFS--WAWRAITYIWLYSLAWA
120 130 140 150 160
190 200 210 220 230 240
pF1KE9 APPIFGWSRYW--PHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQV
. :..::.:: ::: .: : : .. .:... :.. : ..::..: :: ..
NP_055 GAPLLGWNRYILDVHGL--GCTVDWKSKDAND--SSFVLFLFLGCLVVPLGVIAHCYGHI
170 180 190 200 210 220
250 260 270 280 290
pF1KE9 WLAIRAVAKQQKESESTQ-----KAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANP-G
.:: . . .. .. : : ::....: .:::.. ::: :: . :: ..: :
NP_055 LYSIRML-RCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPY-IVICFLVVNGHG
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE9 YAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVS
. : .. . :::: :.::::::::: :.:: .:::.
NP_055 HLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGS
290 300 310 320 330 340
360
pF1KE9 SVSSVSPA
NP_055 EMQIRPIVMSQKDGDRPKKKVTFNSSSIIFIITSDESLSVDDSDKTNGSKVDVIQVRPL
350 360 370 380 390 400
>>NP_006574 (OMIM: 605224) visual pigment-like receptor (337 aa)
initn: 349 init1: 242 opt: 500 Z-score: 498.1 bits: 100.6 E(85289): 5.3e-21
Smith-Waterman score: 500; 28.7% identity (64.5% similar) in 307 aa overlap (53-356:25-328)
30 40 50 60 70 80
pF1KE9 TQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFK
........:.. :...: .::. .:.:
NP_006 MLRNNLGNSSDSKNEDGSVFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYK
10 20 30 40 50
90 100 110 120 130 140
pF1KE9 KLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMC-VLEGYTVSLCGITGL
.:: : : :..::::.:.. . :. .: .... : . .:. : : : .. . :....
NP_006 ELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYGSWKFGYAGCQVYAGLNI-FFGMASI
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE9 WSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWSAVWTAPPIFGWSRYWPHGLKT
:.... .:.:..: : . :. .. : : .:: . :. ::.::. : : .
NP_006 GLLTVVAVDRYLTICLPDVGRRMTTNTYIGLILGAWINGLFWALMPIIGWASYAPDPTGA
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE9 SCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRA-VAKQQKESESTQ
.: . ... . :: ..... :.::.... :: .: :.:. .... :: . .
NP_006 TCTINWRKNDR--SFVSYTMTVIAINFIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRD
180 190 200 210 220 230
270 280 290 300 310
pF1KE9 KAEK-EVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAALPAYFAKSATIYNP
... .::.: :.:: . : :.::.. .:. . . : :: . ::::.:.:::
NP_006 WSDQIDVTKMSVIMICMFLVAWSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNP
240 250 260 270 280 290
320 330 340 350 360
pF1KE9 VIYVFMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSSVSPA
::: :..:: .: .: .. . ..: .::
NP_006 CIYVVANKKFRRAMLAMFKCQTHQTMPVTSILPMDVSQNPLASGRI
300 310 320 330
>>NP_859528 (OMIM: 609042) opsin-5 [Homo sapiens] (354 aa)
initn: 340 init1: 234 opt: 436 Z-score: 436.0 bits: 89.2 E(85289): 1.5e-17
Smith-Waterman score: 436; 24.8% identity (61.0% similar) in 315 aa overlap (51-357:30-344)
30 40 50 60 70
pF1KE9 DSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVTA-SVFTNGLVLAATM
: :.. ... .. :.: :: :: .
NP_859 MALNHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSS
10 20 30 40 50
80 90 100 110 120 130
pF1KE9 KFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGIT
. :: .: . . .:::: ::. .:... ..:.. .:.: : :.. . :
NP_859 RRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCG
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE9 GLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWSAVWTAPPIFGWSRYWPHGL
.: ... .: .:.: .: .: . : : . .: : ... ::. :. : . : :. .
NP_859 SLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPF
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE9 KTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQ----QKE
::: : . ... : : ... .. : ..: :.:.. :... ... .:. ...
NP_859 GTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSR
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE9 SESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAALPAYFAKSAT
.:.. : ..:...... .. . : ::. . ..: . .. ....:. .::::.
NP_859 IHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAA
240 250 260 270 280 290
320 330 340 350 360
pF1KE9 IYNPVIYVFMNRQFRNCI---LQLFGKKVDDGSELSSASKTEVSSVSSVSPA
.:::.:: .. .: : :. :: .: .: ... .. ::
NP_859 MYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEWE
300 310 320 330 340 350
>>XP_016865905 (OMIM: 609042) PREDICTED: opsin-5 isoform (408 aa)
initn: 340 init1: 234 opt: 436 Z-score: 435.5 bits: 89.3 E(85289): 1.6e-17
Smith-Waterman score: 436; 24.8% identity (61.0% similar) in 315 aa overlap (51-357:30-344)
30 40 50 60 70
pF1KE9 DSTQSSIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSVWMIFVVTA-SVFTNGLVLAATM
: :.. ... .. :.: :: :: .
XP_016 MALNHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSS
10 20 30 40 50
80 90 100 110 120 130
pF1KE9 KFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGIT
. :: .: . . .:::: ::. .:... ..:.. .:.: : :.. . :
XP_016 RRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCG
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE9 GLWSLAIISWERWLVVCKPFGNVRFDAKLAIVGIAFSWIWSAVWTAPPIFGWSRYWPHGL
.: ... .: .:.: .: .: . : : . .: : ... ::. :. : . : :. .
XP_016 SLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPF
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE9 KTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQ----QKE
::: : . ... : : ... .. : ..: :.:.. :... ... .:. ...
XP_016 GTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSR
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE9 SESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAALPAYFAKSAT
.:.. : ..:...... .. . : ::. . ..: . .. ....:. .::::.
XP_016 IHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAA
240 250 260 270 280 290
320 330 340 350 360
pF1KE9 IYNPVIYVFMNRQFRNCI---LQLFGKKVDDGSELSSASKTEVSSVSSVSPA
.:::.:: .. .: : :. :: .: .: ... .. ::
XP_016 MYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEDKGRLWH
300 310 320 330 340 350
XP_016 QLSCGENSEMTASSETLGTKAHSPLQETREGENEAVGGNNKCSGCEECI
360 370 380 390 400
>>XP_016865900 (OMIM: 609042) PREDICTED: opsin-5 isoform (298 aa)
initn: 308 init1: 202 opt: 405 Z-score: 406.7 bits: 83.6 E(85289): 6.5e-16
Smith-Waterman score: 405; 25.4% identity (61.8% similar) in 283 aa overlap (82-357:7-288)
60 70 80 90 100 110
pF1KE9 VYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISI
:::: : . . .:::: ::. .:... ..:
XP_016 MSSRRKKKLR-PAEIMTINLAVCDLGISVVGKPFTI
10 20 30
120 130 140 150 160 170
pF1KE9 VNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLAIV
.. .:.: : :.. . : .: ... .: .:.: .: .: . : : .
XP_016 ISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYI
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE9 GIAFSWIWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIP
.: : ... ::. :. : . : :. . ::: : . ... : : ... .. : ..:
XP_016 CLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLP
100 110 120 130 140 150
240 250 260 270 280
pF1KE9 LAIIMLCYLQVWLAIRAVAKQ----QKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFF
:.:.. :... ... .:. ... .:.. : ..:...... .. . : ::.
XP_016 TAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVV
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE9 ACFAAANPGYAFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCI---LQLFGKKVDDG
. ..: . .. ....:. .::::..:::.:: .. .: : :. :: .:
XP_016 SVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEG
220 230 240 250 260 270
350 360
pF1KE9 SELSSASKTEVSSVSSVSPA
.: ... .. ::
XP_016 FRLHTVTTVRKSSAVLEIHEEWE
280 290
>>NP_150598 (OMIM: 606665) melanopsin isoform 1 [Homo sa (478 aa)
initn: 445 init1: 137 opt: 371 Z-score: 372.0 bits: 77.8 E(85289): 5.6e-14
Smith-Waterman score: 500; 28.0% identity (63.9% similar) in 346 aa overlap (18-335:27-363)
10 20 30 40
pF1KE9 MAQQWSLQRLAGRHPQDSYEDSTQSSIFTY----TNSNSTRGPFEG-----
:. ::.:::: . . : .. : . .
NP_150 MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 PNYHIAPRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAE
:. . . : : .: ...: .... : :. . . ..:: : : ...::::.:.
NP_150 PTVDVPDHAHYTLGTV-ILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLM
70 80 90 100 110
110 120 130 140 150
pF1KE9 TVIASTISIVNQVSGYFVLGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKP---F
. . . ..... ...:. : . .. .: ::... .:. :. .:.::. .: :
NP_150 SFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATF
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE9 GNV-RFDAKLAIVGIAFSWIWSAVWTAPPIFGWSRYWPHGLKTSCGPDVFSGSSYPGVQS
: . . : ....:. :... .:. ::.:::: : :.:: :::. : .: . :.:..
NP_150 GVASKRRAAFVLLGV---WLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFT--PAVRA
180 190 200 210 220 230
220 230 240 250 260
pF1KE9 YMIVLMVTCCII---PLAIIMLCYLQVWLAIRAVAKQQK-------ESEST---QKAEKE
: ..: ::.. :: ::. ::. .. ::: ... . ..:: :. ..:
NP_150 YTMLL---CCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSE
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE9 --VTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFHPLMAALPAYFAKSATIYNPVIYV
........:. . . :.::. : : :. .... : :...:: .::...:.::.::.
NP_150 CKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYA
300 310 320 330 340 350
330 340 350 360
pF1KE9 FMNRQFRNCILQLFGKKVDDGSELSSASKTEVSSVSSVSPA
. . ..: : :
NP_150 ITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQES
360 370 380 390 400 410
364 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:42:59 2016 done: Sun Nov 6 12:43:00 2016
Total Scan time: 6.830 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]