Result of FASTA (omim) for
pFN21AE9516
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9516, 742 aa
1>>>pF1KE9516 742 - 742 aa - 742 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5452+/-0.000508; mu= 14.1383+/- 0.031
mean_var=175.6258+/-33.933, 0's: 0 Z-trim(114.1): 482 B-trim: 86 in 1/50
Lambda= 0.096779
statistics sampled from 23114 (23717) to 23114 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.278), width: 16
Scan time: 7.680
The best scores are: opt bits E(85289)
NP_001775 (OMIM: 601211) CD97 antigen isoform 2 pr ( 742) 5086 723.9 5.9e-208
NP_510966 (OMIM: 601211) CD97 antigen isoform 1 pr ( 835) 4452 635.4 2.8e-181
XP_016883036 (OMIM: 601211) PREDICTED: CD97 antige ( 835) 4452 635.4 2.8e-181
NP_001020331 (OMIM: 601211) CD97 antigen isoform 3 ( 786) 4425 631.6 3.7e-180
XP_011526753 (OMIM: 601211) PREDICTED: CD97 antige ( 827) 4401 628.3 3.9e-179
XP_011526255 (OMIM: 125630,606100) PREDICTED: adhe ( 744) 1885 276.9 2e-73
NP_001965 (OMIM: 600493) adhesion G protein-couple ( 886) 1341 201.1 1.7e-50
XP_011526096 (OMIM: 600493) PREDICTED: adhesion G ( 978) 1341 201.1 1.8e-50
NP_001243183 (OMIM: 600493) adhesion G protein-cou ( 745) 1308 196.4 3.6e-49
NP_001257981 (OMIM: 125630,606100) adhesion G prot ( 765) 1289 193.7 2.3e-48
XP_011526254 (OMIM: 125630,606100) PREDICTED: adhe ( 779) 1289 193.7 2.4e-48
XP_011526256 (OMIM: 125630,606100) PREDICTED: adhe ( 724) 1287 193.4 2.7e-48
XP_016882215 (OMIM: 125630,606100) PREDICTED: adhe ( 798) 1286 193.3 3.2e-48
NP_038475 (OMIM: 125630,606100) adhesion G protein ( 823) 1286 193.3 3.3e-48
XP_011526250 (OMIM: 125630,606100) PREDICTED: adhe ( 837) 1286 193.4 3.3e-48
XP_011526253 (OMIM: 125630,606100) PREDICTED: adhe ( 788) 1267 190.7 2e-47
XP_011526257 (OMIM: 125630,606100) PREDICTED: adhe ( 638) 1074 163.6 2.3e-39
NP_001243184 (OMIM: 600493) adhesion G protein-cou ( 709) 1040 158.9 6.5e-38
XP_016856287 (OMIM: 607018) PREDICTED: adhesion G (1163) 982 151.1 2.4e-35
XP_016856286 (OMIM: 607018) PREDICTED: adhesion G (1173) 982 151.1 2.4e-35
NP_001284634 (OMIM: 607018) adhesion G protein-cou (1177) 982 151.1 2.5e-35
XP_016856284 (OMIM: 607018) PREDICTED: adhesion G (1181) 982 151.1 2.5e-35
XP_016856285 (OMIM: 607018) PREDICTED: adhesion G (1186) 982 151.1 2.5e-35
XP_016856283 (OMIM: 607018) PREDICTED: adhesion G (1191) 982 151.1 2.5e-35
XP_016856282 (OMIM: 607018) PREDICTED: adhesion G (1225) 982 151.1 2.5e-35
NP_001284633 (OMIM: 607018) adhesion G protein-cou (1403) 982 151.2 2.7e-35
NP_036434 (OMIM: 607018) adhesion G protein-couple (1403) 982 151.2 2.7e-35
XP_016856281 (OMIM: 607018) PREDICTED: adhesion G (1408) 982 151.2 2.7e-35
NP_001317574 (OMIM: 607018) adhesion G protein-cou (1416) 982 151.2 2.8e-35
XP_016856279 (OMIM: 607018) PREDICTED: adhesion G (1421) 982 151.2 2.8e-35
XP_016856278 (OMIM: 607018) PREDICTED: adhesion G (1446) 982 151.2 2.8e-35
XP_005270725 (OMIM: 607018) PREDICTED: adhesion G (1446) 982 151.2 2.8e-35
XP_016856277 (OMIM: 607018) PREDICTED: adhesion G (1451) 982 151.2 2.8e-35
XP_005270723 (OMIM: 607018) PREDICTED: adhesion G (1459) 982 151.2 2.8e-35
XP_016856276 (OMIM: 607018) PREDICTED: adhesion G (1459) 982 151.2 2.8e-35
XP_016856275 (OMIM: 607018) PREDICTED: adhesion G (1463) 982 151.2 2.8e-35
XP_016856274 (OMIM: 607018) PREDICTED: adhesion G (1463) 982 151.2 2.8e-35
XP_016856272 (OMIM: 607018) PREDICTED: adhesion G (1464) 982 151.2 2.8e-35
XP_016856271 (OMIM: 607018) PREDICTED: adhesion G (1464) 982 151.2 2.8e-35
XP_006710548 (OMIM: 607018) PREDICTED: adhesion G (1464) 982 151.2 2.8e-35
XP_006710552 (OMIM: 607018) PREDICTED: adhesion G (1464) 982 151.2 2.8e-35
XP_006710551 (OMIM: 607018) PREDICTED: adhesion G (1464) 982 151.2 2.8e-35
XP_016856273 (OMIM: 607018) PREDICTED: adhesion G (1464) 982 151.2 2.8e-35
XP_011526251 (OMIM: 125630,606100) PREDICTED: adhe ( 826) 975 149.9 3.9e-35
NP_001284635 (OMIM: 607018) adhesion G protein-cou (1123) 977 150.4 3.9e-35
XP_016881969 (OMIM: 616416) PREDICTED: adhesion G (1420) 974 150.1 6e-35
XP_011526103 (OMIM: 616416) PREDICTED: adhesion G (1425) 974 150.1 6e-35
NP_055736 (OMIM: 616416) adhesion G protein-couple (1469) 974 150.1 6.1e-35
NP_001008701 (OMIM: 616416) adhesion G protein-cou (1474) 974 150.1 6.1e-35
XP_016881968 (OMIM: 616416) PREDICTED: adhesion G (1476) 974 150.1 6.1e-35
>>NP_001775 (OMIM: 601211) CD97 antigen isoform 2 prepro (742 aa)
initn: 5086 init1: 5086 opt: 5086 Z-score: 3854.5 bits: 723.9 E(85289): 5.9e-208
Smith-Waterman score: 5086; 100.0% identity (100.0% similar) in 742 aa overlap (1-742:1-742)
10 20 30 40 50 60
pF1KE9 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 SSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 TLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 LEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAED
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 PGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 NTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 QVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 PIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 GLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 WSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTW
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 VFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEF
670 680 690 700 710 720
730 740
pF1KE9 TSTTSGTGHNQTRALRASESGI
::::::::::::::::::::::
NP_001 TSTTSGTGHNQTRALRASESGI
730 740
>>NP_510966 (OMIM: 601211) CD97 antigen isoform 1 prepro (835 aa)
initn: 4250 init1: 4250 opt: 4452 Z-score: 3375.5 bits: 635.4 E(85289): 2.8e-181
Smith-Waterman score: 4452; 90.8% identity (94.4% similar) in 728 aa overlap (21-742:115-835)
10 20 30 40
pF1KE9 MGGRVFLAFCVWLTLPGAETQDSRGCA---RWCPQNSSCVNATA---CRC
:: : : : . ..:::. . :.:
NP_510 TEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQC
90 100 110 120 130 140
50 60 70 80 90 100
pF1KE9 NPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAK
::: ..: ..: :.::: : .. : . . : :. :::.: : ::..:. :.
NP_510 LPGF----KFIPEDPKVCTDVNEC-TSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSP
150 160 170 180 190
110 120 130 140 150 160
pF1KE9 TFKNESENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCE
. :.. .:.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 NGPNNT--VCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCE
200 210 220 230 240 250
170 180 190 200 210 220
pF1KE9 DMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 DMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEA
260 270 280 290 300 310
230 240 250 260 270 280
pF1KE9 LAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 LAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQS
320 330 340 350 360 370
290 300 310 320 330 340
pF1KE9 SARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 SARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGV
380 390 400 410 420 430
350 360 370 380 390 400
pF1KE9 QLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 QLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAF
440 450 460 470 480 490
410 420 430 440 450 460
pF1KE9 WKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 WKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLAL
500 510 520 530 540 550
470 480 490 500 510 520
pF1KE9 SLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 SLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAG
560 570 580 590 600 610
530 540 550 560 570 580
pF1KE9 LLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 LLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKG
620 630 640 650 660 670
590 600 610 620 630 640
pF1KE9 YGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 YGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARA
680 690 700 710 720 730
650 660 670 680 690 700
pF1KE9 LTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 LTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEY
740 750 760 770 780 790
710 720 730 740
pF1KE9 RKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI
::::::::::::::::::::::::::::::::::::::
NP_510 RKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI
800 810 820 830
>--
initn: 845 init1: 845 opt: 845 Z-score: 653.7 bits: 131.8 E(85289): 1.1e-29
Smith-Waterman score: 845; 100.0% identity (100.0% similar) in 114 aa overlap (1-114:1-114)
10 20 30 40 50 60
pF1KE9 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 SSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQ
NP_510 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNN
130 140 150 160 170 180
>>XP_016883036 (OMIM: 601211) PREDICTED: CD97 antigen is (835 aa)
initn: 4250 init1: 4250 opt: 4452 Z-score: 3375.5 bits: 635.4 E(85289): 2.8e-181
Smith-Waterman score: 4452; 90.8% identity (94.4% similar) in 728 aa overlap (21-742:115-835)
10 20 30 40
pF1KE9 MGGRVFLAFCVWLTLPGAETQDSRGCA---RWCPQNSSCVNATA---CRC
:: : : : . ..:::. . :.:
XP_016 TEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQC
90 100 110 120 130 140
50 60 70 80 90 100
pF1KE9 NPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAK
::: ..: ..: :.::: : .. : . . : :. :::.: : ::..:. :.
XP_016 LPGF----KFIPEDPKVCTDVNEC-TSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSP
150 160 170 180 190
110 120 130 140 150 160
pF1KE9 TFKNESENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCE
. :.. .:.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGPNNT--VCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCE
200 210 220 230 240 250
170 180 190 200 210 220
pF1KE9 DMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEA
260 270 280 290 300 310
230 240 250 260 270 280
pF1KE9 LAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQS
320 330 340 350 360 370
290 300 310 320 330 340
pF1KE9 SARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGV
380 390 400 410 420 430
350 360 370 380 390 400
pF1KE9 QLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAF
440 450 460 470 480 490
410 420 430 440 450 460
pF1KE9 WKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLAL
500 510 520 530 540 550
470 480 490 500 510 520
pF1KE9 SLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAG
560 570 580 590 600 610
530 540 550 560 570 580
pF1KE9 LLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKG
620 630 640 650 660 670
590 600 610 620 630 640
pF1KE9 YGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARA
680 690 700 710 720 730
650 660 670 680 690 700
pF1KE9 LTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEY
740 750 760 770 780 790
710 720 730 740
pF1KE9 RKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI
::::::::::::::::::::::::::::::::::::::
XP_016 RKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI
800 810 820 830
>--
initn: 845 init1: 845 opt: 845 Z-score: 653.7 bits: 131.8 E(85289): 1.1e-29
Smith-Waterman score: 845; 100.0% identity (100.0% similar) in 114 aa overlap (1-114:1-114)
10 20 30 40 50 60
pF1KE9 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 SSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQ
XP_016 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNN
130 140 150 160 170 180
>>NP_001020331 (OMIM: 601211) CD97 antigen isoform 3 pre (786 aa)
initn: 4251 init1: 4251 opt: 4425 Z-score: 3355.4 bits: 631.6 E(85289): 3.7e-180
Smith-Waterman score: 4894; 94.3% identity (94.3% similar) in 774 aa overlap (13-742:13-786)
10 20 30 40 50 60
pF1KE9 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
70 80 90 100 110 120
130
pF1KE9 --------------------------------------------SSGQHQCDSSTVCFNT
::::::::::::::::
NP_001 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVDECSSGQHQCDSSTVCFNT
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE9 VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDS
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE9 KTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGP
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE9 FTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTT
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE9 LLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHL
370 380 390 400 410 420
380 390 400 410 420 430
pF1KE9 ESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSH
430 440 450 460 470 480
440 450 460 470 480 490
pF1KE9 LSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCIC
490 500 510 520 530 540
500 510 520 530 540 550
pF1KE9 LFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQG
550 560 570 580 590 600
560 570 580 590 600 610
pF1KE9 LSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAV
610 620 630 640 650 660
620 630 640 650 660 670
pF1KE9 IFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTY
670 680 690 700 710 720
680 690 700 710 720 730
pF1KE9 VFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALR
730 740 750 760 770 780
740
pF1KE9 ASESGI
::::::
NP_001 ASESGI
>>XP_011526753 (OMIM: 601211) PREDICTED: CD97 antigen is (827 aa)
initn: 4199 init1: 4199 opt: 4401 Z-score: 3337.0 bits: 628.3 E(85289): 3.9e-179
Smith-Waterman score: 4401; 90.7% identity (94.3% similar) in 719 aa overlap (21-733:115-826)
10 20 30 40
pF1KE9 MGGRVFLAFCVWLTLPGAETQDSRGCA---RWCPQNSSCVNATA---CRC
:: : : : . ..:::. . :.:
XP_011 TEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQC
90 100 110 120 130 140
50 60 70 80 90 100
pF1KE9 NPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAK
::: ..: ..: :.::: : .. : . . : :. :::.: : ::..:. :.
XP_011 LPGF----KFIPEDPKVCTDVNEC-TSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSP
150 160 170 180 190
110 120 130 140 150 160
pF1KE9 TFKNESENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCE
. :.. .:.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGPNNT--VCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCE
200 210 220 230 240 250
170 180 190 200 210 220
pF1KE9 DMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEA
260 270 280 290 300 310
230 240 250 260 270 280
pF1KE9 LAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQS
320 330 340 350 360 370
290 300 310 320 330 340
pF1KE9 SARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGV
380 390 400 410 420 430
350 360 370 380 390 400
pF1KE9 QLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAF
440 450 460 470 480 490
410 420 430 440 450 460
pF1KE9 WKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLAL
500 510 520 530 540 550
470 480 490 500 510 520
pF1KE9 SLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAG
560 570 580 590 600 610
530 540 550 560 570 580
pF1KE9 LLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKG
620 630 640 650 660 670
590 600 610 620 630 640
pF1KE9 YGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARA
680 690 700 710 720 730
650 660 670 680 690 700
pF1KE9 LTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEY
740 750 760 770 780 790
710 720 730 740
pF1KE9 RKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI
:::::::::::::::::::::::::::::
XP_011 RKWACLVAGGSKYSEFTSTTSGTGHNQTRN
800 810 820
>--
initn: 845 init1: 845 opt: 845 Z-score: 653.8 bits: 131.8 E(85289): 1.1e-29
Smith-Waterman score: 845; 100.0% identity (100.0% similar) in 114 aa overlap (1-114:1-114)
10 20 30 40 50 60
pF1KE9 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 SSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQ
XP_011 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNN
130 140 150 160 170 180
>>XP_011526255 (OMIM: 125630,606100) PREDICTED: adhesion (744 aa)
initn: 2913 init1: 1871 opt: 1885 Z-score: 1439.0 bits: 276.9 E(85289): 2e-73
Smith-Waterman score: 2879; 56.9% identity (79.3% similar) in 744 aa overlap (1-733:1-725)
10 20 30 40 50
pF1KE9 MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT
::::::: :::::::::::::::::::::::::.::::::::::::::::::::::::
XP_011 MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
: ::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE9 HSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQL
:::::::::::::::::: : . :. :::.... .:::.:::::.:.: .: .:..:
XP_011 HSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE9 LSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAG
:..:::..: :.:.: .: ... :..:::.: .:.. :..::. :..: :.:.: :
XP_011 LDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE9 AEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFL
. ::::.:.:..:: .: :::.: : :. .:: :.: ... .. . :: : : ::
XP_011 SGDPGPSVVGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE9 SHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWAT
:.:.:..:.::. :.::: ..:.: ::..::.::. .. :::::
XP_011 SNNDTQNLSSPVTFTFSH--------------RSVIP--RQKVLCVFWEHGQNGCGHWAT
370 380 390 400
420 430 440 450 460 470
pF1KE9 EGCQVLGSKNGSTTCQCSHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILT
::...:... :: :.:.::::::.::::::: :: ::.:: .::..::.:::: ::
XP_011 TGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALT
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE9 FLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFC
::: . ::.. :..::.: .:::.. .::..:.. : .: : ..:: ::: .::..
XP_011 FLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLT
470 480 490 500 510 520
540 550 560 570 580
pF1KE9 WMSLEGLELYFLVVRVFQGQGLST------RWLCLIGYGVPLLIVGVSAAIYSKGYGRPR
:: ::.: : ::..: . . :. . . .::::: . :..::: . :: :
XP_011 WMLLEALYL-FLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPS
530 540 550 560 570 580
590 600 610 620 630 640
pF1KE9 YCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITA
:::. :.::.:.::::: :. : :.:..:.: : ...: .: ... :...: :.. :
XP_011 RCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKA
590 600 610 620 630 640
650 660 670 680 690 700
pF1KE9 IAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC
::::.::::: .:.. . :..:.:::.: :::.:..:..:::...:::.: ::.
XP_011 TAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSK
650 660 670 680 690 700
710 720 730 740
pF1KE9 LVAGGSKYSEFTSTTSGTGHNQTRALRASESGI
. . ::. . .:.. . ..
XP_011 GIRKLKTESEMHTLSSSAKADTSKPSTEAYKDGASEKEQDGAK
710 720 730 740
>>NP_001965 (OMIM: 600493) adhesion G protein-coupled re (886 aa)
initn: 1129 init1: 579 opt: 1341 Z-score: 1027.7 bits: 201.1 E(85289): 1.7e-50
Smith-Waterman score: 1354; 32.2% identity (62.8% similar) in 748 aa overlap (21-724:171-872)
10 20 30 40
pF1KE9 MGGRVFLAFCVWLTLPGAETQDSRGCA--RWCPQNSSCVNAT---ACRCN
.: :: : ::....: :.. .: ::
NP_001 VCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCN
150 160 170 180 190 200
50 60 70 80 90 100
pF1KE9 PGFSSFSEIITTP--TETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGA
::: : : .. .:.::.::. : : : :: ::: :.: ::. : .:
NP_001 PGFESSSGHLSFQGLKASCEDIDECTE----MCPINSTCTNTPGSYFCTCHPGFAPSNGQ
210 220 230 240 250
110 120 130 140 150 160
pF1KE9 KTFKNESENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDT--
.: ... . :.:.::: . : ...: :..::::: : :..: ..:::
NP_001 LNFTDQGVE-CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNP--EGSQKDGNF
260 270 280 290 300 310
170 180 190 200 210
pF1KE9 VCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT----IQNVIKLVDELME
:. . :. ..: .:. . . .. : :. :.:.....:.. :
NP_001 SCQRVLFKCKEDVIPDNKQ--------IQQCQEGTAVKPAYVSFCAQINNIFSVLDKVCE
320 330 340 350 360
220 230 240 250 260
pF1KE9 APGDV-------EALAPPVRHLIA--------TQLLSN--LEDIMRILAKSLPKGPFTYI
: :...: .... . :. :.. ::.. . :. : : . :
NP_001 NKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLASFWK-PSANI
370 380 390 400 410 420
270 280 290 300 310
pF1KE9 SPS------NTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGI--LSIQ
.:. . : .. .: ...:::. . :.. . .. :. . ..:. .:.
NP_001 TPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEESESTETTGVAFVSFV
430 440 450 460 470 480
320 330 340 350 360 370
pF1KE9 NMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFA
.: ..: . .. : :: : . ..:. : : . ... .. ...::...
NP_001 GMESVLNERFFKDH---QAPL------TTSEIKLKMNSRVVGGIMTGEKKDGFSDPIIYT
490 500 510 520 530
380 390 400 410 420 430
pF1KE9 FSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTC
. ... : : : .:. :..: .::.:.. :: .: ... : :
NP_001 LENIQ---------PKQKFERP------ICVSWSTDV-KGGRWTSFGCVILEASETYTIC
540 550 560 570
440 450 460 470 480 490
pF1KE9 QCSHLSSFAILMAHYDVE-DWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHL
.:......:..:: .. :..: .:..::. .:: ::.: : :::: : :.. : .::
NP_001 SCNQMANLAVIMASGELTMDFSLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHL
580 590 600 610 620 630
500 510 520 530 540
pF1KE9 HLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLV---
:::.::....:.:::::.. ...: : ..::.::: ::: : :: .:.. :...:
NP_001 HLCVCLLLAKTLFLAGIHKTDNKMG--CAIIAGFLHYLFLACFFWMLVEAVILFLMVRNL
640 650 660 670 680 690
550 560 570 580 590 600
pF1KE9 --VRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGP
: :...... .: .:::.:.:.: .::.. .::: :::. : ::.::::::
NP_001 KVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGP
700 710 720 730 740 750
610 620 630 640 650 660
pF1KE9 VTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFI
: .:. :..... :.: : :..: .: ... :: .: ::. :.::::.:::.::.:.:
NP_001 VCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQ
760 770 780 790 800 810
670 680 690 700 710 720
pF1KE9 FDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSG
. . :..:.:::.: :::::..:.::::: .:::::..: ..: .: : ..:.
NP_001 IGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRW---ITGKTKPSSQSQTSRI
820 830 840 850 860 870
730 740
pF1KE9 TGHNQTRALRASESGI
NP_001 LLSSMPSASKTG
880
>>XP_011526096 (OMIM: 600493) PREDICTED: adhesion G prot (978 aa)
initn: 1177 init1: 579 opt: 1341 Z-score: 1027.2 bits: 201.1 E(85289): 1.8e-50
Smith-Waterman score: 1354; 32.2% identity (62.9% similar) in 749 aa overlap (20-724:262-964)
10 20 30 40
pF1KE9 MGGRVFLAFCVWLTLPGAETQDSRGCA--RWCPQNSSCVNAT---ACRC
..: :: : ::....: :.. .: :
XP_011 SVCPEHSDCVNSMGSYNCSCQVGFISRNSISSDVDECADPRACPEHATCNNTVGNYSCFC
240 250 260 270 280 290
50 60 70 80 90 100
pF1KE9 NPGFSSFSEIITTP--TETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSG
:::: : : .. .:.::.::. : : : :: ::: :.: ::. : .:
XP_011 NPGFESSSGHLSFQGLKASCEDIDECTE----MCPINSTCTNTPGSYFCTCHPGFAPSNG
300 310 320 330 340
110 120 130 140 150 160
pF1KE9 AKTFKNESENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDT-
.: ... . :.:.::: . : ...: :..::::: : :..: ..:::
XP_011 QLNFTDQGVE-CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNP--EGSQKDGN
350 360 370 380 390 400
170 180 190 200 210
pF1KE9 -VCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT----IQNVIKLVDELM
:. . :. ..: .:. . . .. : :. :.:.....:..
XP_011 FSCQRVLFKCKEDVIPDNKQ--------IQQCQEGTAVKPAYVSFCAQINNIFSVLDKVC
410 420 430 440 450
220 230 240 250
pF1KE9 EAPGDV-------EALAPPVRHLIA--------TQLLSN--LEDIMRILAKSLPKGPFTY
: : :...: .... . :. :.. ::.. . :. : : .
XP_011 ENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLASFWK-PSAN
460 470 480 490 500 510
260 270 280 290 300 310
pF1KE9 ISPS------NTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGI--LSI
:.:. . : .. .: ...:::. . :.. . .. :. . ..:. .:.
XP_011 ITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEESESTETTGVAFVSF
520 530 540 550 560 570
320 330 340 350 360 370
pF1KE9 QNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILF
.: ..: . .. : :: : . ..:. : : . ... .. ...::..
XP_011 VGMESVLNERFFKDH---QAPL------TTSEIKLKMNSRVVGGIMTGEKKDGFSDPIIY
580 590 600 610 620
380 390 400 410 420 430
pF1KE9 AFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTT
.. ... : : : .:. :..: .::.:.. :: .: ... :
XP_011 TLENIQ---------PKQKFERP------ICVSWSTDV-KGGRWTSFGCVILEASETYTI
630 640 650 660 670
440 450 460 470 480 490
pF1KE9 CQCSHLSSFAILMAHYDVE-DWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIH
:.:......:..:: .. :..: .:..::. .:: ::.: : :::: : :.. : .:
XP_011 CSCNQMANLAVIMASGELTMDFSLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLH
680 690 700 710 720 730
500 510 520 530 540
pF1KE9 LHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLV--
::::.::....:.:::::.. ...: : ..::.::: ::: : :: .:.. :...:
XP_011 LHLCVCLLLAKTLFLAGIHKTDNKMG--CAIIAGFLHYLFLACFFWMLVEAVILFLMVRN
740 750 760 770 780
550 560 570 580 590 600
pF1KE9 ---VRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLG
: :...... .: .:::.:.:.: .::.. .::: :::. : ::.:::::
XP_011 LKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLG
790 800 810 820 830 840
610 620 630 640 650 660
pF1KE9 PVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLF
:: .:. :..... :.: : :..: .: ... :: .: ::. :.::::.:::.::.:.:
XP_011 PVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIF
850 860 870 880 890 900
670 680 690 700 710 720
pF1KE9 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTS
. . :..:.:::.: :::::..:.::::: .:::::..: ..: .: : ..:.
XP_011 QIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRW---ITGKTKPSSQSQTSR
910 920 930 940 950 960
730 740
pF1KE9 GTGHNQTRALRASESGI
XP_011 ILLSSMPSASKTG
970
>--
initn: 334 init1: 133 opt: 329 Z-score: 263.6 bits: 59.8 E(85289): 6.1e-08
Smith-Waterman score: 329; 33.7% identity (54.7% similar) in 181 aa overlap (16-183:74-242)
10 20 30 40
pF1KE9 MGGRVFLAFCVWLTLPGAETQDSRGCARW---CPQNSSCVNATA-
::.. .: :.. : :::: : ..
XP_011 YATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSPQPCGPNSSCKNLSGR
50 60 70 80 90 100
50 60 70 80 90
pF1KE9 --CRCNPGFSSFSEIITTPTE----TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSP
: : :::: . .: . .: ::::: : : : . ::: :. :::.: :.
XP_011 YKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSS--VCPEHSDCVNSMGSYSCSCQV
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE9 GYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHG--
:. .: .: .::.:.::::.. . : .. : : : :.: : :.. :
XP_011 GF--IS-----RN---STCEDIDECSQSPQPCGPNSSCKNMSGRYKCSCLDGFSSPTGND
170 180 190 200 210
160 170 180 190 200 210
pF1KE9 -IPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLV
::.. . : :.. : . ::. ..
XP_011 WIPGKPGNFSCTDISESLTSSVCPEHSDCVNSMGSYNCSCQVGFISRNSISSDVDECADP
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE9 DELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQ
XP_011 RACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTP
280 290 300 310 320 330
>>NP_001243183 (OMIM: 600493) adhesion G protein-coupled (745 aa)
initn: 1119 init1: 579 opt: 1308 Z-score: 1003.6 bits: 196.4 E(85289): 3.6e-49
Smith-Waterman score: 1321; 31.3% identity (61.9% similar) in 770 aa overlap (5-724:8-731)
10 20 30 40
pF1KE9 MGGRVFLAFCVWLTLPG----AETQDSRG--C--ARWCPQNSSCVNATA---CRCNP
.: . :: . : .. ...: : . :: ..:.:.. : :.
NP_001 MRGFNLLLFWGCCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 GF--SSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAK
:: :. .. . : : ::.::. : : : :: ::: :.: ::. : .:
NP_001 GFLSSNGQNHFKDPGVRCKDIDECTE----MCPINSTCTNTPGSYFCTCHPGFAPSNGQL
70 80 90 100 110
110 120 130 140 150 160
pF1KE9 TFKNESENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDT--V
.: ... . :.:.::: . : ...: :..::::: : :..: ..:::
NP_001 NFTDQGVE-CRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNP--EGSQKDGNFS
120 130 140 150 160 170
170 180 190 200 210
pF1KE9 CEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT----IQNVIKLVDELMEA
:. . :. ..: .:. . . .. : :. :.:.....:.. :
NP_001 CQRVLFKCKEDVIPDNKQ--------IQQCQEGTAVKPAYVSFCAQINNIFSVLDKVCEN
180 190 200 210 220
220 230 240 250 260
pF1KE9 PGDV-------EALAPPVRHLIA--------TQLLSN--LEDIMRILAKSLPKGPFTYIS
: :...: .... . :. :.. ::.. . :. : : . :.
NP_001 KTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLASFWK-PSANIT
230 240 250 260 270 280
270 280 290 300 310
pF1KE9 PS------NTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGI--LSIQN
:. . : .. .: ...:::. . :.. . .. :. . ..:. .:. .
NP_001 PAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEESESTETTGVAFVSFVG
290 300 310 320 330 340
320 330 340 350 360 370
pF1KE9 MTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAF
: ..: . .. : :: : . ..:. : : . ... .. ...::....
NP_001 MESVLNERFFKDH---QAPL------TTSEIKLKMNSRVVGGIMTGEKKDGFSDPIIYTL
350 360 370 380 390
380 390 400 410 420 430
pF1KE9 SHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQ
... : : : .:. :..: .::.:.. :: .: ... : :.
NP_001 ENIQ---------PKQKFERP------ICVSWSTDV-KGGRWTSFGCVILEASETYTICS
400 410 420 430
440 450 460 470 480 490
pF1KE9 CSHLSSFAILMAHYDVE-DWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLH
:......:..:: .. :..: .:..::. .:: ::.: : :::: : :.. : .:::
NP_001 CNQMANLAVIMASGELTMDFSLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLH
440 450 460 470 480 490
500 510 520 530 540
pF1KE9 LCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLV----
::.::....:.:::::.. ...: : ..::.::: ::: : :: .:.. :...:
NP_001 LCVCLLLAKTLFLAGIHKTDNKMG--CAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLK
500 510 520 530 540 550
550 560 570 580 590 600
pF1KE9 -VRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPV
: :...... .: .:::.:.:.: .::.. .::: :::. : ::.:::::::
NP_001 VVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPV
560 570 580 590 600 610
610 620 630 640 650 660
pF1KE9 TFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIF
.:. :..... :.: : :..: .: ... :: .: ::. :.::::.:::.::.:.: .
NP_001 CTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQI
620 630 640 650 660 670
670 680 690 700 710 720
pF1KE9 DDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGT
. :..:.:::.: :::::..:.::::: .:::::..: ..: .: : ..:.
NP_001 GPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRW---ITGKTKPSSQSQTSRIL
680 690 700 710 720 730
730 740
pF1KE9 GHNQTRALRASESGI
NP_001 LSSMPSASKTG
740
>>NP_001257981 (OMIM: 125630,606100) adhesion G protein- (765 aa)
initn: 2787 init1: 1077 opt: 1289 Z-score: 989.2 bits: 193.7 E(85289): 2.3e-48
Smith-Waterman score: 1917; 43.3% identity (67.0% similar) in 725 aa overlap (21-733:118-760)
10 20 30 40
pF1KE9 MGGRVFLAFCVWLTLPGAETQDSRGCA---RWCPQNSSCVNATA---CRC
:: : : : . ..:::. . :.:
NP_001 TEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQC
90 100 110 120 130 140
50 60 70 80 90 100
pF1KE9 NPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAK
:::. : : . : :.::: : .. : . . : :. :::.: : ::..:. :.
NP_001 LPGFKLKPE---DP-KLCTDVNEC-TSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSP
150 160 170 180 190 200
110 120 130 140 150 160
pF1KE9 TFKNESENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCE
. :.. .:.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGPNNT--VCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCE
210 220 230 240 250 260
170 180 190 200 210 220
pF1KE9 DMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEA
::::::::::::::::::::::::::::::: : . :. :::.... .:::.:::::.:.
NP_001 DMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLET
270 280 290 300 310 320
230 240 250 260 270 280
pF1KE9 LAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQS
: .: .:..::..:::..: :.:.: .: ... :..:::.: .:.. :..::. :.
NP_001 LPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQN
330 340 350 360 370 380
290 300 310 320 330 340
pF1KE9 SARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGV
.: :.:.: : . ::::.:.:..:: .: :::.: : :. .:: :.: ... ..
NP_001 QAVMQLDWNQAQKSGDPGPSVVGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDG
390 400 410 420 430 440
350 360 370 380 390 400
pF1KE9 QLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAF
. :: : : :::.:.:..:.::. :.::: :
NP_001 SPILLSDVISAFLSNNDTQNLSSPVTFTFSHRE---------------------------
450 460 470
410 420 430 440 450 460
pF1KE9 WKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLAL
:: ::.:: .::..
NP_001 ---------------------------------------------EDPVLTVITYMGLSV
480
470 480 490 500 510 520
pF1KE9 SLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAG
::.:::: ::::: . ::.. :..::.: .:::.. .::..:.. : .: : ..::
NP_001 SLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAG
490 500 510 520 530 540
530 540 550 560 570
pF1KE9 LLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLST------RWLCLIGYGVPLLIVGVSA
::: .::.. :: ::.: : ::..: . . :. . . .::::: . :..::
NP_001 TLHYLYLATLTWMLLEALYL-FLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISA
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE9 AIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKK
: . :: : :::. :.::.:.::::: :. : :.:..:.: : ...: .: ...
NP_001 ASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVST
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE9 LKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNK
:...: :.. : ::::.::::: .:.. . :..:.:::.: :::.:..:..:::..
NP_001 LRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQ
670 680 690 700 710 720
700 710 720 730 740
pF1KE9 KVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI
.:::.: ::. . . ::. . .:.. . ..
NP_001 QVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN
730 740 750 760
>--
initn: 790 init1: 790 opt: 804 Z-score: 623.2 bits: 126.0 E(85289): 5.7e-28
Smith-Waterman score: 804; 94.9% identity (95.7% similar) in 117 aa overlap (1-114:1-117)
10 20 30 40 50
pF1KE9 MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT
::::::: :::::::::::::::::::::::::.::::::::::::::::::::::::
NP_001 MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
: ::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_001 PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV
NP_001 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC
130 140 150 160 170 180
742 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:44:16 2016 done: Mon Nov 7 18:44:17 2016
Total Scan time: 7.680 Total Display time: 0.180
Function used was FASTA [36.3.4 Apr, 2011]