Result of FASTA (omim) for
pFN21AE9510
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9510, 479 aa
1>>>pF1KE9510 479 - 479 aa - 479 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0281+/-0.000402; mu= -1.1355+/- 0.026
mean_var=301.6552+/-64.371, 0's: 0 Z-trim(120.9): 382 B-trim: 1772 in 1/59
Lambda= 0.073845
statistics sampled from 36359 (36859) to 36359 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.432), width: 16
Scan time: 11.090
The best scores are: opt bits E(85289)
NP_000732 (OMIM: 118495) muscarinic acetylcholine ( 479) 3162 350.2 7.2e-96
XP_011514071 (OMIM: 118493) PREDICTED: muscarinic ( 466) 1744 199.2 2.1e-50
NP_001006633 (OMIM: 118493) muscarinic acetylcholi ( 466) 1744 199.2 2.1e-50
NP_001006632 (OMIM: 118493) muscarinic acetylcholi ( 466) 1744 199.2 2.1e-50
NP_001006630 (OMIM: 118493) muscarinic acetylcholi ( 466) 1744 199.2 2.1e-50
NP_001006629 (OMIM: 118493) muscarinic acetylcholi ( 466) 1744 199.2 2.1e-50
NP_000730 (OMIM: 118493) muscarinic acetylcholine ( 466) 1744 199.2 2.1e-50
NP_001006628 (OMIM: 118493) muscarinic acetylcholi ( 466) 1744 199.2 2.1e-50
NP_001006627 (OMIM: 118493) muscarinic acetylcholi ( 466) 1744 199.2 2.1e-50
NP_001006631 (OMIM: 118493) muscarinic acetylcholi ( 466) 1744 199.2 2.1e-50
NP_036257 (OMIM: 118496) muscarinic acetylcholine ( 532) 961 115.8 3e-25
NP_001307846 (OMIM: 118496) muscarinic acetylcholi ( 532) 961 115.8 3e-25
XP_011542343 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_016855648 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_016855643 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_011542347 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_016855641 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_011542346 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_016855649 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_016855645 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_011542348 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_016855646 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_011542345 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_005273089 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_016855650 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_016855652 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_011542349 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_016855647 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_016855644 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_016855642 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
XP_016855651 (OMIM: 100100,118494) PREDICTED: musc ( 590) 950 114.7 7.3e-25
NP_000731 (OMIM: 100100,118494) muscarinic acetylc ( 590) 950 114.7 7.3e-25
XP_011543044 (OMIM: 118510) PREDICTED: muscarinic ( 460) 935 113.0 1.8e-24
NP_000729 (OMIM: 118510) muscarinic acetylcholine ( 460) 935 113.0 1.8e-24
NP_009163 (OMIM: 604525) histamine H3 receptor [Ho ( 445) 502 66.8 1.4e-10
XP_005260323 (OMIM: 604525) PREDICTED: histamine H ( 453) 502 66.8 1.4e-10
NP_001091681 (OMIM: 600167) histamine H1 receptor ( 487) 450 61.3 6.9e-09
NP_000852 (OMIM: 600167) histamine H1 receptor [Ho ( 487) 450 61.3 6.9e-09
XP_016861773 (OMIM: 600167) PREDICTED: histamine H ( 487) 450 61.3 6.9e-09
XP_011531955 (OMIM: 600167) PREDICTED: histamine H ( 487) 450 61.3 6.9e-09
NP_001091683 (OMIM: 600167) histamine H1 receptor ( 487) 450 61.3 6.9e-09
XP_016861772 (OMIM: 600167) PREDICTED: histamine H ( 487) 450 61.3 6.9e-09
NP_001091682 (OMIM: 600167) histamine H1 receptor ( 487) 450 61.3 6.9e-09
XP_011531954 (OMIM: 600167) PREDICTED: histamine H ( 487) 450 61.3 6.9e-09
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390) 446 60.8 7.8e-09
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308) 432 59.2 1.9e-08
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317) 432 59.2 1.9e-08
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324) 432 59.3 1.9e-08
NP_001309433 (OMIM: 104221) alpha-1A adrenergic re ( 342) 432 59.3 2e-08
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370) 432 59.3 2.1e-08
>>NP_000732 (OMIM: 118495) muscarinic acetylcholine rece (479 aa)
initn: 3162 init1: 3162 opt: 3162 Z-score: 1842.1 bits: 350.2 E(85289): 7.2e-96
Smith-Waterman score: 3162; 100.0% identity (100.0% similar) in 479 aa overlap (1-479:1-479)
10 20 30 40 50 60
pF1KE9 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 ATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 PATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMV
370 380 390 400 410 420
430 440 450 460 470
pF1KE9 LVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
430 440 450 460 470
>>XP_011514071 (OMIM: 118493) PREDICTED: muscarinic acet (466 aa)
initn: 1686 init1: 1158 opt: 1744 Z-score: 1025.9 bits: 199.2 E(85289): 2.1e-50
Smith-Waterman score: 1744; 57.7% identity (79.4% similar) in 480 aa overlap (7-479:1-466)
10 20 30 40 50 60
pF1KE9 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
.:.:..... :. .: :.: :.:::. :.:::::::..::::::.:::::
XP_011 MNNSTNSSNNSLALTSP---YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVN
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
:.::::::::::::::::::::.:::::::.: . :::::: ::::::::::::::::::
XP_011 RHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
:::::::::::::::::::::..:::::::.::::::::::.:::::::::::.:: :::
XP_011 MNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
:..:.:::.:: :::::::::::::::.:::::: ::: ::.::..: . : ..
XP_011 EDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPV
180 190 200 210 220 230
250 260 270 280 290
pF1KE9 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVA--DKDTSNESSS
. ..... ..: . .. : .. . :...:.... : : : .:..::.:.:
XP_011 SPSLVQGRIVKPNNNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTS
240 250 260 270 280
300 310 320 330 340 350
pF1KE9 GSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNE-CV---
::. :... : : . .. . :. . :.: :: .. :.
XP_011 VSAV-------ASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTN
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE9 TAIEIVPATPAGMRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTW
:..:.: .. . : ::::...... : ::. .::.::::::.:::::::.::
XP_011 TTVEVVGSSGQNGDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITW
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE9 TPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYR
.:::::::.:::: :::.:::.:::::::.::::::::::::::::::::.:::.:.:.
XP_011 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYK
410 420 430 440 450 460
pF1KE9 NIGTAR
:::..:
XP_011 NIGATR
>>NP_001006633 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 1686 init1: 1158 opt: 1744 Z-score: 1025.9 bits: 199.2 E(85289): 2.1e-50
Smith-Waterman score: 1744; 57.7% identity (79.4% similar) in 480 aa overlap (7-479:1-466)
10 20 30 40 50 60
pF1KE9 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
.:.:..... :. .: :.: :.:::. :.:::::::..::::::.:::::
NP_001 MNNSTNSSNNSLALTSP---YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVN
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
:.::::::::::::::::::::.:::::::.: . :::::: ::::::::::::::::::
NP_001 RHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
:::::::::::::::::::::..:::::::.::::::::::.:::::::::::.:: :::
NP_001 MNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
:..:.:::.:: :::::::::::::::.:::::: ::: ::.::..: . : ..
NP_001 EDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPV
180 190 200 210 220 230
250 260 270 280 290
pF1KE9 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVA--DKDTSNESSS
. ..... ..: . .. : .. . :...:.... : : : .:..::.:.:
NP_001 SPSLVQGRIVKPNNNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTS
240 250 260 270 280
300 310 320 330 340 350
pF1KE9 GSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNE-CV---
::. :... : : . .. . :. . :.: :: .. :.
NP_001 VSAV-------ASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTN
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE9 TAIEIVPATPAGMRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTW
:..:.: .. . : ::::...... : ::. .::.::::::.:::::::.::
NP_001 TTVEVVGSSGQNGDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITW
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE9 TPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYR
.:::::::.:::: :::.:::.:::::::.::::::::::::::::::::.:::.:.:.
NP_001 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYK
410 420 430 440 450 460
pF1KE9 NIGTAR
:::..:
NP_001 NIGATR
>>NP_001006632 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 1686 init1: 1158 opt: 1744 Z-score: 1025.9 bits: 199.2 E(85289): 2.1e-50
Smith-Waterman score: 1744; 57.7% identity (79.4% similar) in 480 aa overlap (7-479:1-466)
10 20 30 40 50 60
pF1KE9 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
.:.:..... :. .: :.: :.:::. :.:::::::..::::::.:::::
NP_001 MNNSTNSSNNSLALTSP---YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVN
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
:.::::::::::::::::::::.:::::::.: . :::::: ::::::::::::::::::
NP_001 RHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
:::::::::::::::::::::..:::::::.::::::::::.:::::::::::.:: :::
NP_001 MNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
:..:.:::.:: :::::::::::::::.:::::: ::: ::.::..: . : ..
NP_001 EDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPV
180 190 200 210 220 230
250 260 270 280 290
pF1KE9 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVA--DKDTSNESSS
. ..... ..: . .. : .. . :...:.... : : : .:..::.:.:
NP_001 SPSLVQGRIVKPNNNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTS
240 250 260 270 280
300 310 320 330 340 350
pF1KE9 GSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNE-CV---
::. :... : : . .. . :. . :.: :: .. :.
NP_001 VSAV-------ASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTN
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE9 TAIEIVPATPAGMRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTW
:..:.: .. . : ::::...... : ::. .::.::::::.:::::::.::
NP_001 TTVEVVGSSGQNGDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITW
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE9 TPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYR
.:::::::.:::: :::.:::.:::::::.::::::::::::::::::::.:::.:.:.
NP_001 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYK
410 420 430 440 450 460
pF1KE9 NIGTAR
:::..:
NP_001 NIGATR
>>NP_001006630 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 1686 init1: 1158 opt: 1744 Z-score: 1025.9 bits: 199.2 E(85289): 2.1e-50
Smith-Waterman score: 1744; 57.7% identity (79.4% similar) in 480 aa overlap (7-479:1-466)
10 20 30 40 50 60
pF1KE9 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
.:.:..... :. .: :.: :.:::. :.:::::::..::::::.:::::
NP_001 MNNSTNSSNNSLALTSP---YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVN
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
:.::::::::::::::::::::.:::::::.: . :::::: ::::::::::::::::::
NP_001 RHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
:::::::::::::::::::::..:::::::.::::::::::.:::::::::::.:: :::
NP_001 MNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
:..:.:::.:: :::::::::::::::.:::::: ::: ::.::..: . : ..
NP_001 EDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPV
180 190 200 210 220 230
250 260 270 280 290
pF1KE9 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVA--DKDTSNESSS
. ..... ..: . .. : .. . :...:.... : : : .:..::.:.:
NP_001 SPSLVQGRIVKPNNNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTS
240 250 260 270 280
300 310 320 330 340 350
pF1KE9 GSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNE-CV---
::. :... : : . .. . :. . :.: :: .. :.
NP_001 VSAV-------ASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTN
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE9 TAIEIVPATPAGMRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTW
:..:.: .. . : ::::...... : ::. .::.::::::.:::::::.::
NP_001 TTVEVVGSSGQNGDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITW
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE9 TPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYR
.:::::::.:::: :::.:::.:::::::.::::::::::::::::::::.:::.:.:.
NP_001 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYK
410 420 430 440 450 460
pF1KE9 NIGTAR
:::..:
NP_001 NIGATR
>>NP_001006629 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 1686 init1: 1158 opt: 1744 Z-score: 1025.9 bits: 199.2 E(85289): 2.1e-50
Smith-Waterman score: 1744; 57.7% identity (79.4% similar) in 480 aa overlap (7-479:1-466)
10 20 30 40 50 60
pF1KE9 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
.:.:..... :. .: :.: :.:::. :.:::::::..::::::.:::::
NP_001 MNNSTNSSNNSLALTSP---YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVN
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
:.::::::::::::::::::::.:::::::.: . :::::: ::::::::::::::::::
NP_001 RHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
:::::::::::::::::::::..:::::::.::::::::::.:::::::::::.:: :::
NP_001 MNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
:..:.:::.:: :::::::::::::::.:::::: ::: ::.::..: . : ..
NP_001 EDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPV
180 190 200 210 220 230
250 260 270 280 290
pF1KE9 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVA--DKDTSNESSS
. ..... ..: . .. : .. . :...:.... : : : .:..::.:.:
NP_001 SPSLVQGRIVKPNNNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTS
240 250 260 270 280
300 310 320 330 340 350
pF1KE9 GSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNE-CV---
::. :... : : . .. . :. . :.: :: .. :.
NP_001 VSAV-------ASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTN
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE9 TAIEIVPATPAGMRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTW
:..:.: .. . : ::::...... : ::. .::.::::::.:::::::.::
NP_001 TTVEVVGSSGQNGDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITW
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE9 TPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYR
.:::::::.:::: :::.:::.:::::::.::::::::::::::::::::.:::.:.:.
NP_001 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYK
410 420 430 440 450 460
pF1KE9 NIGTAR
:::..:
NP_001 NIGATR
>>NP_000730 (OMIM: 118493) muscarinic acetylcholine rece (466 aa)
initn: 1686 init1: 1158 opt: 1744 Z-score: 1025.9 bits: 199.2 E(85289): 2.1e-50
Smith-Waterman score: 1744; 57.7% identity (79.4% similar) in 480 aa overlap (7-479:1-466)
10 20 30 40 50 60
pF1KE9 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
.:.:..... :. .: :.: :.:::. :.:::::::..::::::.:::::
NP_000 MNNSTNSSNNSLALTSP---YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVN
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
:.::::::::::::::::::::.:::::::.: . :::::: ::::::::::::::::::
NP_000 RHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
:::::::::::::::::::::..:::::::.::::::::::.:::::::::::.:: :::
NP_000 MNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
:..:.:::.:: :::::::::::::::.:::::: ::: ::.::..: . : ..
NP_000 EDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPV
180 190 200 210 220 230
250 260 270 280 290
pF1KE9 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVA--DKDTSNESSS
. ..... ..: . .. : .. . :...:.... : : : .:..::.:.:
NP_000 SPSLVQGRIVKPNNNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTS
240 250 260 270 280
300 310 320 330 340 350
pF1KE9 GSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNE-CV---
::. :... : : . .. . :. . :.: :: .. :.
NP_000 VSAV-------ASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTN
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE9 TAIEIVPATPAGMRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTW
:..:.: .. . : ::::...... : ::. .::.::::::.:::::::.::
NP_000 TTVEVVGSSGQNGDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITW
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE9 TPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYR
.:::::::.:::: :::.:::.:::::::.::::::::::::::::::::.:::.:.:.
NP_000 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYK
410 420 430 440 450 460
pF1KE9 NIGTAR
:::..:
NP_000 NIGATR
>>NP_001006628 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 1686 init1: 1158 opt: 1744 Z-score: 1025.9 bits: 199.2 E(85289): 2.1e-50
Smith-Waterman score: 1744; 57.7% identity (79.4% similar) in 480 aa overlap (7-479:1-466)
10 20 30 40 50 60
pF1KE9 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
.:.:..... :. .: :.: :.:::. :.:::::::..::::::.:::::
NP_001 MNNSTNSSNNSLALTSP---YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVN
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
:.::::::::::::::::::::.:::::::.: . :::::: ::::::::::::::::::
NP_001 RHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
:::::::::::::::::::::..:::::::.::::::::::.:::::::::::.:: :::
NP_001 MNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
:..:.:::.:: :::::::::::::::.:::::: ::: ::.::..: . : ..
NP_001 EDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPV
180 190 200 210 220 230
250 260 270 280 290
pF1KE9 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVA--DKDTSNESSS
. ..... ..: . .. : .. . :...:.... : : : .:..::.:.:
NP_001 SPSLVQGRIVKPNNNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTS
240 250 260 270 280
300 310 320 330 340 350
pF1KE9 GSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNE-CV---
::. :... : : . .. . :. . :.: :: .. :.
NP_001 VSAV-------ASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTN
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE9 TAIEIVPATPAGMRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTW
:..:.: .. . : ::::...... : ::. .::.::::::.:::::::.::
NP_001 TTVEVVGSSGQNGDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITW
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE9 TPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYR
.:::::::.:::: :::.:::.:::::::.::::::::::::::::::::.:::.:.:.
NP_001 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYK
410 420 430 440 450 460
pF1KE9 NIGTAR
:::..:
NP_001 NIGATR
>>NP_001006627 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 1686 init1: 1158 opt: 1744 Z-score: 1025.9 bits: 199.2 E(85289): 2.1e-50
Smith-Waterman score: 1744; 57.7% identity (79.4% similar) in 480 aa overlap (7-479:1-466)
10 20 30 40 50 60
pF1KE9 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
.:.:..... :. .: :.: :.:::. :.:::::::..::::::.:::::
NP_001 MNNSTNSSNNSLALTSP---YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVN
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
:.::::::::::::::::::::.:::::::.: . :::::: ::::::::::::::::::
NP_001 RHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
:::::::::::::::::::::..:::::::.::::::::::.:::::::::::.:: :::
NP_001 MNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
:..:.:::.:: :::::::::::::::.:::::: ::: ::.::..: . : ..
NP_001 EDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPV
180 190 200 210 220 230
250 260 270 280 290
pF1KE9 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVA--DKDTSNESSS
. ..... ..: . .. : .. . :...:.... : : : .:..::.:.:
NP_001 SPSLVQGRIVKPNNNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTS
240 250 260 270 280
300 310 320 330 340 350
pF1KE9 GSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNE-CV---
::. :... : : . .. . :. . :.: :: .. :.
NP_001 VSAV-------ASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTN
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE9 TAIEIVPATPAGMRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTW
:..:.: .. . : ::::...... : ::. .::.::::::.:::::::.::
NP_001 TTVEVVGSSGQNGDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITW
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE9 TPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYR
.:::::::.:::: :::.:::.:::::::.::::::::::::::::::::.:::.:.:.
NP_001 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYK
410 420 430 440 450 460
pF1KE9 NIGTAR
:::..:
NP_001 NIGATR
>>NP_001006631 (OMIM: 118493) muscarinic acetylcholine r (466 aa)
initn: 1686 init1: 1158 opt: 1744 Z-score: 1025.9 bits: 199.2 E(85289): 2.1e-50
Smith-Waterman score: 1744; 57.7% identity (79.4% similar) in 480 aa overlap (7-479:1-466)
10 20 30 40 50 60
pF1KE9 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
.:.:..... :. .: :.: :.:::. :.:::::::..::::::.:::::
NP_001 MNNSTNSSNNSLALTSP---YKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVN
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
:.::::::::::::::::::::.:::::::.: . :::::: ::::::::::::::::::
NP_001 RHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
:::::::::::::::::::::..:::::::.::::::::::.:::::::::::.:: :::
NP_001 MNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
:..:.:::.:: :::::::::::::::.:::::: ::: ::.::..: . : ..
NP_001 EDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPV
180 190 200 210 220 230
250 260 270 280 290
pF1KE9 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVA--DKDTSNESSS
. ..... ..: . .. : .. . :...:.... : : : .:..::.:.:
NP_001 SPSLVQGRIVKPNNNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTS
240 250 260 270 280
300 310 320 330 340 350
pF1KE9 GSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNE-CV---
::. :... : : . .. . :. . :.: :: .. :.
NP_001 VSAV-------ASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTN
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE9 TAIEIVPATPAGMRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTW
:..:.: .. . : ::::...... : ::. .::.::::::.:::::::.::
NP_001 TTVEVVGSSGQNGDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITW
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE9 TPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYR
.:::::::.:::: :::.:::.:::::::.::::::::::::::::::::.:::.:.:.
NP_001 APYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYK
410 420 430 440 450 460
pF1KE9 NIGTAR
:::..:
NP_001 NIGATR
479 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 10:47:54 2016 done: Sun Nov 6 10:47:56 2016
Total Scan time: 11.090 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]