Result of FASTA (omim) for
pFN21AE9506
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9506, 332 aa
1>>>pF1KE9506 332 - 332 aa - 332 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.3181+/-0.000498; mu= 21.5269+/- 0.031
mean_var=131.0901+/-39.623, 0's: 0 Z-trim(107.4): 369 B-trim: 975 in 1/47
Lambda= 0.112018
statistics sampled from 14939 (15497) to 14939 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.511), E-opt: 0.2 (0.182), width: 16
Scan time: 7.090
The best scores are: opt bits E(85289)
NP_005903 (OMIM: 155541,601665) melanocortin recep ( 332) 2182 365.1 1.1e-100
NP_005904 (OMIM: 600042) melanocortin receptor 5 [ ( 325) 1318 225.5 1.2e-58
NP_063941 (OMIM: 155540,602025,607948) melanocorti ( 323) 1273 218.2 1.9e-56
NP_002377 (OMIM: 155555,203200,266300,613098,61309 ( 317) 982 171.2 2.7e-42
XP_016881270 (OMIM: 202200,607397) PREDICTED: adre ( 297) 934 163.4 5.6e-40
NP_001278840 (OMIM: 202200,607397) adrenocorticotr ( 297) 934 163.4 5.6e-40
NP_000520 (OMIM: 202200,607397) adrenocorticotropi ( 297) 934 163.4 5.6e-40
NP_005217 (OMIM: 601965) sphingosine 1-phosphate r ( 378) 377 73.5 7.8e-13
XP_016882958 (OMIM: 605110) PREDICTED: lysophospha ( 351) 369 72.2 1.8e-12
NP_004711 (OMIM: 605110) lysophosphatidic acid rec ( 351) 369 72.2 1.8e-12
XP_011526723 (OMIM: 605110) PREDICTED: lysophospha ( 351) 369 72.2 1.8e-12
XP_016882957 (OMIM: 605110) PREDICTED: lysophospha ( 351) 369 72.2 1.8e-12
NP_004221 (OMIM: 605111,610419,610419) sphingosine ( 353) 364 71.4 3.2e-12
XP_005251838 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869887 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_005251839 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869878 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869873 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869880 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869894 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869877 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869890 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869888 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869892 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869883 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869872 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869881 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869884 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869895 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
NP_001392 (OMIM: 602282) lysophosphatidic acid rec ( 364) 346 68.5 2.5e-11
XP_016869896 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869879 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869891 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869874 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869889 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869882 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
NP_476500 (OMIM: 602282) lysophosphatidic acid rec ( 364) 346 68.5 2.5e-11
XP_016869876 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869885 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869875 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869886 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
XP_016869893 (OMIM: 602282) PREDICTED: lysophospha ( 364) 346 68.5 2.5e-11
NP_001391 (OMIM: 601974) sphingosine 1-phosphate r ( 382) 317 63.8 6.5e-10
NP_001307659 (OMIM: 601974) sphingosine 1-phosphat ( 382) 317 63.8 6.5e-10
NP_036284 (OMIM: 605106) lysophosphatidic acid rec ( 353) 299 60.9 4.7e-09
NP_005275 (OMIM: 600553) G-protein coupled recepto ( 362) 264 55.2 2.4e-07
NP_001273028 (OMIM: 600553) G-protein coupled rece ( 377) 264 55.3 2.5e-07
NP_003691 (OMIM: 608494) olfactory receptor 2D2 [H ( 308) 263 55.0 2.5e-07
NP_001159687 (OMIM: 605146) sphingosine 1-phosphat ( 398) 259 54.5 4.4e-07
NP_110387 (OMIM: 605146) sphingosine 1-phosphate r ( 398) 259 54.5 4.4e-07
>>NP_005903 (OMIM: 155541,601665) melanocortin receptor (332 aa)
initn: 2182 init1: 2182 opt: 2182 Z-score: 1928.4 bits: 365.1 E(85289): 1.1e-100
Smith-Waterman score: 2182; 100.0% identity (100.0% similar) in 332 aa overlap (1-332:1-332)
10 20 30 40 50 60
pF1KE9 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
250 260 270 280 290 300
310 320 330
pF1KE9 IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
::::::::::::::::::::::::::::::::
NP_005 IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
310 320 330
>>NP_005904 (OMIM: 600042) melanocortin receptor 5 [Homo (325 aa)
initn: 1297 init1: 1010 opt: 1318 Z-score: 1173.8 bits: 225.5 E(85289): 1.2e-58
Smith-Waterman score: 1318; 62.2% identity (84.5% similar) in 328 aa overlap (9-331:1-324)
10 20 30 40 50
pF1KE9 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYS----DGGCYEQLFVSPEVFVTLGV
:..:.:: :. ::.:. .: . .. : :.. .. :::.::::
NP_005 MNSSFHL---HFLDLNLNATEGNLSGPNVKNKSSPC-EDMGIAVEVFLTLGV
10 20 30 40
60 70 80 90 100 110
pF1KE9 ISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTD-TDAQ
:::::::::: ::.::::::::::::.:::::::::::.:.. :::.: :::. . :.
NP_005 ISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIAD
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE9 SFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWA
.:. .::::.::.:: :..::.::::.:::::: ::::::.::.:::..: : ::. :::
NP_005 AFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWA
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE9 ACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAI
:: ::.::.::.:. ::.:::.:::.:: :..:::.::::.:: :.::::.:::...
NP_005 FCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE9 RQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNS
:: ..:.::.:.:.:.:::.:::::::::: ...::::: :: ::::::.:::::::::
NP_005 RQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNS
230 240 250 260 270 280
300 310 320 330
pF1KE9 IIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
..::::::.::::.:::::::::: . :.. :
NP_005 VMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD
290 300 310 320
>>NP_063941 (OMIM: 155540,602025,607948) melanocortin re (323 aa)
initn: 1267 init1: 514 opt: 1273 Z-score: 1134.5 bits: 218.2 E(85289): 1.9e-56
Smith-Waterman score: 1273; 61.3% identity (85.8% similar) in 302 aa overlap (26-319:16-317)
10 20 30 40 50
pF1KE9 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGY----SDGGCYEQLFVSPEVFVTLGV
:.:: : . :... ::.:..::::..::.
NP_063 MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGI
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 ISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTD-TDAQ
.:::::::::.:...: :::::::::.::::::::::::::. :::.:....: : .
NP_063 VSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFED
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 SFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWA
.: ..::..::.:: ::.::::.::.:::::: ::::::.::.::::... .: ::.
NP_063 QFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 ACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAI
: : :..::.::.:. ::.:::::::.:. ::..:::::::.::::.::::.:: . ..
NP_063 CCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 --RQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMC
.: . ::::.:.:::.:::. :::::::::.. :.:: ::::.:. .::: ::.::::
NP_063 APQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMC
240 250 260 270 280 290
300 310 320 330
pF1KE9 NSIIDPLIYALRSQELRKTFKEIIC-CYPLGGLCDLSSRY
::.:::::::.:: :::.::.::.: :
NP_063 NSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
300 310 320
>>NP_002377 (OMIM: 155555,203200,266300,613098,613099) m (317 aa)
initn: 982 init1: 398 opt: 982 Z-score: 880.5 bits: 171.2 E(85289): 2.7e-42
Smith-Waterman score: 982; 51.2% identity (78.1% similar) in 297 aa overlap (27-319:20-315)
10 20 30 40 50
pF1KE9 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGG--CYEQLFVSPEVFVTLGVIS
: .:: . .. : : : . .: .:..::..:
NP_002 MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLE-VSISDGLFLSLGLVS
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 LLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFT
:.:: ::...::::.::::::: ::: ::..:.::: :: :: :: ::.. :.. .
NP_002 LVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 VN-IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAAC
.. .::::: . :::.:.:.: : .::::::..:::::.::.:.:. :. .. ::.:
NP_002 LQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVAS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 TVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTG-AIR
.: . ::: : : ::..::...:..::.::: :::::. : : . :: : ..
NP_002 VVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVH
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 QGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSI
:: ..:::.:::::.:.: .::.:::::: . . ::..: : :....:::.: ::.::.:
NP_002 QGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAI
240 250 260 270 280 290
300 310 320 330
pF1KE9 IDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
:::::::..:::::.:.::.. :
NP_002 IDPLIYAFHSQELRRTLKEVLTCSW
300 310
>>XP_016881270 (OMIM: 202200,607397) PREDICTED: adrenoco (297 aa)
initn: 950 init1: 397 opt: 934 Z-score: 838.8 bits: 163.4 E(85289): 5.6e-40
Smith-Waterman score: 934; 47.5% identity (77.6% similar) in 295 aa overlap (26-319:6-293)
10 20 30 40 50 60
pF1KE9 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
:. :.... ... .. . :.: :......:
XP_016 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVL
10 20 30 40
70 80 90 100 110
pF1KE9 ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQ-SFTV
::..:..:. :::::..::::::::::..::: :. . :.:.: : : . :: .
XP_016 ENLIVLLAVFKNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFET
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE9 NIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTV
. :..:::.. :::.:: :: ::.:::.:::.::.::.:.:..:. .... ::. ::
XP_016 TADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE9 SGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGA
.:: ..:.: ..: . ..: ::... :::::::.:: : ..:..:: : :
XP_016 TGITMVIFSHHVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLP-----R--A
170 180 190 200 210
240 250 260 270 280 290
pF1KE9 NMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDP
:::::::::::.:::. ::::: ::.... ::.::::.:.:: :.. .:::::..:::
XP_016 NMKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDP
220 230 240 250 260 270
300 310 320 330
pF1KE9 LIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
.:::.:: ::: .::..: :
XP_016 FIYAFRSPELRDAFKKMIFCSRYW
280 290
>>NP_001278840 (OMIM: 202200,607397) adrenocorticotropic (297 aa)
initn: 950 init1: 397 opt: 934 Z-score: 838.8 bits: 163.4 E(85289): 5.6e-40
Smith-Waterman score: 934; 47.5% identity (77.6% similar) in 295 aa overlap (26-319:6-293)
10 20 30 40 50 60
pF1KE9 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
:. :.... ... .. . :.: :......:
NP_001 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVL
10 20 30 40
70 80 90 100 110
pF1KE9 ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQ-SFTV
::..:..:. :::::..::::::::::..::: :. . :.:.: : : . :: .
NP_001 ENLIVLLAVFKNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFET
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE9 NIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTV
. :..:::.. :::.:: :: ::.:::.:::.::.::.:.:..:. .... ::. ::
NP_001 TADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE9 SGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGA
.:: ..:.: ..: . ..: ::... :::::::.:: : ..:..:: : :
NP_001 TGITMVIFSHHVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLP-----R--A
170 180 190 200 210
240 250 260 270 280 290
pF1KE9 NMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDP
:::::::::::.:::. ::::: ::.... ::.::::.:.:: :.. .:::::..:::
NP_001 NMKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDP
220 230 240 250 260 270
300 310 320 330
pF1KE9 LIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
.:::.:: ::: .::..: :
NP_001 FIYAFRSPELRDAFKKMIFCSRYW
280 290
>>NP_000520 (OMIM: 202200,607397) adrenocorticotropic ho (297 aa)
initn: 950 init1: 397 opt: 934 Z-score: 838.8 bits: 163.4 E(85289): 5.6e-40
Smith-Waterman score: 934; 47.5% identity (77.6% similar) in 295 aa overlap (26-319:6-293)
10 20 30 40 50 60
pF1KE9 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
:. :.... ... .. . :.: :......:
NP_000 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVL
10 20 30 40
70 80 90 100 110
pF1KE9 ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQ-SFTV
::..:..:. :::::..::::::::::..::: :. . :.:.: : : . :: .
NP_000 ENLIVLLAVFKNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFET
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE9 NIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTV
. :..:::.. :::.:: :: ::.:::.:::.::.::.:.:..:. .... ::. ::
NP_000 TADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE9 SGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGA
.:: ..:.: ..: . ..: ::... :::::::.:: : ..:..:: : :
NP_000 TGITMVIFSHHVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLP-----R--A
170 180 190 200 210
240 250 260 270 280 290
pF1KE9 NMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDP
:::::::::::.:::. ::::: ::.... ::.::::.:.:: :.. .:::::..:::
NP_000 NMKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDP
220 230 240 250 260 270
300 310 320 330
pF1KE9 LIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
.:::.:: ::: .::..: :
NP_000 FIYAFRSPELRDAFKKMIFCSRYW
280 290
>>NP_005217 (OMIM: 601965) sphingosine 1-phosphate recep (378 aa)
initn: 253 init1: 128 opt: 377 Z-score: 351.4 bits: 73.5 E(85289): 7.8e-13
Smith-Waterman score: 378; 26.8% identity (64.9% similar) in 291 aa overlap (50-323:45-320)
20 30 40 50 60 70
pF1KE9 SYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPM
.:... . .:::..:..:: ::...:. :
NP_005 NETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRM
20 30 40 50 60 70
80 90 100 110 120 130
pF1KE9 YFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICS
:::: .::. :.:.... : :... : . : :: . . .. . .: :: ::
NP_005 YFFIGNLALCDLLAGIAYK----VNILMSGKKTFSLSPTVWF--LREGSMFVALGASTCS
80 90 100 110 120
140 150 160 170 180 190
pF1KE9 LLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFII-------YSDSSA
::.::..:..:.. .. .. .:: ..:. : . : : :. : :.
NP_005 LLAIAIERHLTMI-KMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCST
130 140 150 160 170 180
200 210 220 230 240
pF1KE9 VI---------ICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKG
.. .: :..: ..:. .. ::........ ...: ... :. : ..
NP_005 ILPLYSKKYIAFC-ISIFTAILVTIVILYARIYFLVKSSSRKVA--NHNNSERSMALLR-
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 AITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYA
:..:...::..::.:.:. ... ..: . . : ... ...: . :: ..:.::.
NP_005 --TVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQW--FIVLAVLNSAMNPVIYT
250 260 270 280 290
310 320 330
pF1KE9 LRSQELRKTFKEIIC-CYPLGGLCDLSSRY
: :.:.:..: ...: : :
NP_005 LASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTA
300 310 320 330 340 350
>>XP_016882958 (OMIM: 605110) PREDICTED: lysophosphatidi (351 aa)
initn: 321 init1: 126 opt: 369 Z-score: 344.7 bits: 72.2 E(85289): 1.8e-12
Smith-Waterman score: 373; 26.8% identity (63.1% similar) in 314 aa overlap (28-319:10-312)
10 20 30 40 50
pF1KE9 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPE--VFVTLG---
.:..: :...: . :. : :.::
XP_016 MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTV
10 20 30 40
60 70 80 90 100 110
pF1KE9 -VISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDA
:. :: :.:::.:::.:. .:.:.:... .::.::....:. . :. : .
XP_016 SVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVA------YLFLMFHTGPRT
50 60 70 80 90
120 130 140 150 160 170
pF1KE9 QSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIW
.... . .... .:: ::. .::.:::.:. ... :.: :. . :: ..: .:
XP_016 ARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVM-AVQLHSRLPRGRVVMLIVGVW
100 110 120 130 140 150
180 190 200 210
pF1KE9 AACTVSGIL------FIIYSDSSAVIICLITMFF-------TMLA--LMASLYVHMFLMA
.: :.: . : . . :.. . ..:. ::...:...:...
XP_016 VAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYV
160 170 180 190 200 210
220 230 240 250 260 270
pF1KE9 RLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFY-ISCPQNPYCV
: ...:.: . . .... . :..:..:.:::::.: . :.. ..: . :
XP_016 RRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCES---C-
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE9 CFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
.. . .:.: ::... .:. :. :.:.::....::
XP_016 NVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQG
280 290 300 310 320 330
XP_016 GASTRIMLPENGHPLMDSTL
340 350
>>NP_004711 (OMIM: 605110) lysophosphatidic acid recepto (351 aa)
initn: 321 init1: 126 opt: 369 Z-score: 344.7 bits: 72.2 E(85289): 1.8e-12
Smith-Waterman score: 373; 26.8% identity (63.1% similar) in 314 aa overlap (28-319:10-312)
10 20 30 40 50
pF1KE9 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPE--VFVTLG---
.:..: :...: . :. : :.::
NP_004 MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTV
10 20 30 40
60 70 80 90 100 110
pF1KE9 -VISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDA
:. :: :.:::.:::.:. .:.:.:... .::.::....:. . :. : .
NP_004 SVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVA------YLFLMFHTGPRT
50 60 70 80 90
120 130 140 150 160 170
pF1KE9 QSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIW
.... . .... .:: ::. .::.:::.:. ... :.: :. . :: ..: .:
NP_004 ARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVM-AVQLHSRLPRGRVVMLIVGVW
100 110 120 130 140 150
180 190 200 210
pF1KE9 AACTVSGIL------FIIYSDSSAVIICLITMFF-------TMLA--LMASLYVHMFLMA
.: :.: . : . . :.. . ..:. ::...:...:...
NP_004 VAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYV
160 170 180 190 200 210
220 230 240 250 260 270
pF1KE9 RLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFY-ISCPQNPYCV
: ...:.: . . .... . :..:..:.:::::.: . :.. ..: . :
NP_004 RRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCES---C-
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE9 CFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
.. . .:.: ::... .:. :. :.:.::....::
NP_004 NVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQG
280 290 300 310 320 330
NP_004 GASTRIMLPENGHPLMDSTL
340 350
332 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:40:07 2016 done: Sun Nov 6 13:40:08 2016
Total Scan time: 7.090 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]