Result of FASTA (omim) for
pFN21AE9503
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9503, 384 aa
1>>>pF1KE9503 384 - 384 aa - 384 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7038+/-0.000372; mu= 20.8451+/- 0.023
mean_var=127.4814+/-34.131, 0's: 0 Z-trim(114.4): 347 B-trim: 1317 in 1/49
Lambda= 0.113593
statistics sampled from 23764 (24275) to 23764 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.285), width: 16
Scan time: 7.630
The best scores are: opt bits E(85289)
NP_003766 (OMIM: 603751) sphingosine 1-phosphate r ( 384) 2540 428.1 1.7e-119
NP_005217 (OMIM: 601965) sphingosine 1-phosphate r ( 378) 852 151.4 3.2e-36
NP_001391 (OMIM: 601974) sphingosine 1-phosphate r ( 382) 828 147.5 5e-35
NP_001307659 (OMIM: 601974) sphingosine 1-phosphat ( 382) 828 147.5 5e-35
NP_004221 (OMIM: 605111,610419,610419) sphingosine ( 353) 691 125.0 2.7e-28
NP_004711 (OMIM: 605110) lysophosphatidic acid rec ( 351) 622 113.7 6.9e-25
XP_016882957 (OMIM: 605110) PREDICTED: lysophospha ( 351) 622 113.7 6.9e-25
XP_011526723 (OMIM: 605110) PREDICTED: lysophospha ( 351) 622 113.7 6.9e-25
XP_016882958 (OMIM: 605110) PREDICTED: lysophospha ( 351) 622 113.7 6.9e-25
NP_110387 (OMIM: 605146) sphingosine 1-phosphate r ( 398) 610 111.8 2.9e-24
NP_001159687 (OMIM: 605146) sphingosine 1-phosphat ( 398) 610 111.8 2.9e-24
XP_016869879 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_005251839 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
NP_001392 (OMIM: 602282) lysophosphatidic acid rec ( 364) 566 104.5 4.1e-22
XP_016869882 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869883 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869878 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869886 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869877 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869887 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869888 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869876 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869894 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869880 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869892 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869893 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869891 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869885 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869890 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869872 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_005251838 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869874 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869884 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869875 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869881 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869896 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
NP_476500 (OMIM: 602282) lysophosphatidic acid rec ( 364) 566 104.5 4.1e-22
XP_016869895 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869873 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
XP_016869889 (OMIM: 602282) PREDICTED: lysophospha ( 364) 566 104.5 4.1e-22
NP_036284 (OMIM: 605106) lysophosphatidic acid rec ( 353) 552 102.2 2e-21
NP_005272 (OMIM: 600241) G-protein coupled recepto ( 330) 384 74.6 3.7e-13
NP_001832 (OMIM: 605051) cannabinoid receptor 2 [H ( 360) 374 73.1 1.2e-12
XP_011538931 (OMIM: 605051) PREDICTED: cannabinoid ( 360) 374 73.1 1.2e-12
XP_016855750 (OMIM: 605051) PREDICTED: cannabinoid ( 360) 374 73.1 1.2e-12
NP_005279 (OMIM: 600752) G-protein coupled recepto ( 334) 346 68.4 2.8e-11
NP_005275 (OMIM: 600553) G-protein coupled recepto ( 362) 327 65.4 2.5e-10
NP_001273028 (OMIM: 600553) G-protein coupled rece ( 377) 327 65.4 2.6e-10
NP_000530 (OMIM: 136880,180380,610445,613731) rhod ( 348) 274 56.6 1e-07
NP_061822 (OMIM: 600896) urotensin-2 receptor [Hom ( 389) 272 56.4 1.3e-07
>>NP_003766 (OMIM: 603751) sphingosine 1-phosphate recep (384 aa)
initn: 2540 init1: 2540 opt: 2540 Z-score: 2266.2 bits: 428.1 E(85289): 1.7e-119
Smith-Waterman score: 2540; 100.0% identity (100.0% similar) in 384 aa overlap (1-384:1-384)
10 20 30 40 50 60
pF1KE9 MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
310 320 330 340 350 360
370 380
pF1KE9 FRGSRSLSFRMREPLSSISSVRSI
::::::::::::::::::::::::
NP_003 FRGSRSLSFRMREPLSSISSVRSI
370 380
>>NP_005217 (OMIM: 601965) sphingosine 1-phosphate recep (378 aa)
initn: 822 init1: 418 opt: 852 Z-score: 771.2 bits: 151.4 E(85289): 3.2e-36
Smith-Waterman score: 858; 42.8% identity (69.0% similar) in 348 aa overlap (28-375:21-355)
10 20 30 40 50 60
pF1KE9 MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
::.. :.:::: . : : .. ..
NP_005 MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFI
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
:::::.:: :: .. . . .:. . :..: :::.: :: .:.:.:: .:: :.:. :::
NP_005 VLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
::: .:.::.::: ::: : :: ::.. . :.: ::. .::.:::.: :: ::
NP_005 REGSMFVALGASTCSLLAIAIERHLTMIK-MRPYDANKRHRVFLLIGMCWLIAFTLGALP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
.:::::: . ::..::::::.:: ::. ::...:.::. ::. :. ::..:..:.
NP_005 ILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANH
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE9 AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
... ::.::.... .:..::.::: :.: :: . . : : .:...::::::
NP_005 NNSERSMALLRTVVIVVSVFIACWSPLFILFLIDV-ACRVQACPILFKAQWFIVLAVLNS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE9 AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
:.::.::.. :.:. :: . : :.:: .:: : ::: . . : : : ..:
NP_005 AMNPVIYTLASKEMRRAFFR-LVCNCL---VRGRG---ARASPIQPA---LDPS-RSKSS
300 310 320 330 340
370 380
pF1KE9 FRGSRSLSFRMREPLSSISSVRSI
.. : : ...: :
NP_005 SSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
350 360 370
>>NP_001391 (OMIM: 601974) sphingosine 1-phosphate recep (382 aa)
initn: 722 init1: 333 opt: 828 Z-score: 749.9 bits: 147.5 E(85289): 5e-35
Smith-Waterman score: 828; 41.0% identity (72.8% similar) in 334 aa overlap (1-326:1-331)
10 20 30 40 50 60
pF1KE9 MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
:. :..:.. .... . .:: :::..:.: . :.. . . . :..
NP_001 MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENS-IKLTSVVFILICCFI
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
.:::..:: .: . . .: .:: . :..:::::.:.:: ::.::::: :..:.::::::
NP_001 ILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
::: .:.::.::.:::: : ::. ::.. ..: ... :.. .:. ::... .:: ::
NP_001 REGSMFVALSASVFSLLAIAIERYITMLKMKLHNG-SNNFRLFLLISACWVISLILGGLP
120 130 140 150 160 170
190 200 210 220 230
pF1KE9 LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQ-----
..::::. :.. ::..:::: :.::::: ..:. .: .:. :: :. ::.. ..
NP_001 IMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 KAPRPAAR--RKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWIL
: :.: .:. :::::...: .:..::.::: ::: :: : .. . . : ...:
NP_001 KNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDV-GCKVKTCDILFRAEYFL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 ALAVLNSAVNPIIYSFRSREVCRAVLSFL-CCGCLRLGMRGPGDCLARAVEAHSGASTTD
.::::::..:::::.. ..:. :: . .. :: :
NP_001 VLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDN
300 310 320 330 340 350
360 370 380
pF1KE9 SSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
NP_001 SSHPQKDEGDNPETIMSSGNVNSSS
360 370 380
>>NP_001307659 (OMIM: 601974) sphingosine 1-phosphate re (382 aa)
initn: 722 init1: 333 opt: 828 Z-score: 749.9 bits: 147.5 E(85289): 5e-35
Smith-Waterman score: 828; 41.0% identity (72.8% similar) in 334 aa overlap (1-326:1-331)
10 20 30 40 50 60
pF1KE9 MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
:. :..:.. .... . .:: :::..:.: . :.. . . . :..
NP_001 MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENS-IKLTSVVFILICCFI
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
.:::..:: .: . . .: .:: . :..:::::.:.:: ::.::::: :..:.::::::
NP_001 ILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
::: .:.::.::.:::: : ::. ::.. ..: ... :.. .:. ::... .:: ::
NP_001 REGSMFVALSASVFSLLAIAIERYITMLKMKLHNG-SNNFRLFLLISACWVISLILGGLP
120 130 140 150 160 170
190 200 210 220 230
pF1KE9 LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQ-----
..::::. :.. ::..:::: :.::::: ..:. .: .:. :: :. ::.. ..
NP_001 IMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 KAPRPAAR--RKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWIL
: :.: .:. :::::...: .:..::.::: ::: :: : .. . . : ...:
NP_001 KNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDV-GCKVKTCDILFRAEYFL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 ALAVLNSAVNPIIYSFRSREVCRAVLSFL-CCGCLRLGMRGPGDCLARAVEAHSGASTTD
.::::::..:::::.. ..:. :: . .. :: :
NP_001 VLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDN
300 310 320 330 340 350
360 370 380
pF1KE9 SSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
NP_001 SSHPQKDEGDNPETIMSSGNVNSSS
360 370 380
>>NP_004221 (OMIM: 605111,610419,610419) sphingosine 1-p (353 aa)
initn: 653 init1: 277 opt: 691 Z-score: 628.9 bits: 125.0 E(85289): 2.7e-28
Smith-Waterman score: 691; 41.8% identity (70.4% similar) in 280 aa overlap (54-333:41-314)
30 40 50 60 70 80
pF1KE9 LIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYY
: : .:.:::::: :.. . . . .:
NP_004 PNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYL
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE9 CLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGER
: :.. ::::.:.:..::.::::. :.::.:.::: ::: : .:.::.:::: : ::
NP_004 FLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIER
80 90 100 110 120 130
150 160 170 180 190 200
pF1KE9 FATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKR
..... : :. :. :. .:: ::.. .:: ::.:::::: .. ::..::::.:.
NP_004 HVAIAK-VKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKH
140 150 160 170 180
210 220 230 240 250 260
pF1KE9 YILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVC
:.: ..::. .: .:..:: :. .:..: : .. ::::: ..: .:.::
NP_004 YVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAP----QTLALLKTVTIVLGVFIVC
190 200 210 220 230 240
270 280 290 300 310 320
pF1KE9 WGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLC
: : :..:: : .. . . : ...:...::: .::.::..:::.. : :: :
NP_004 WLPAFSILLLD-YACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQ
250 260 270 280 290 300
330 340 350 360 370 380
pF1KE9 CGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRS
: .:..:
NP_004 CWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
310 320 330 340 350
>>NP_004711 (OMIM: 605110) lysophosphatidic acid recepto (351 aa)
initn: 588 init1: 233 opt: 622 Z-score: 567.8 bits: 113.7 E(85289): 6.9e-25
Smith-Waterman score: 622; 39.0% identity (64.0% similar) in 336 aa overlap (21-350:9-335)
10 20 30 40 50
pF1KE9 MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGR-LAGRGGPEDGGLGALRGLSVAASCL
... : . ::.::. :... :.: . :: ::.: : :
NP_004 MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVAL-GLTV--SVL
10 20 30 40
60 70 80 90 100 110
pF1KE9 VVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWF
:.: ::::.:::.:. : .. .:: : :.. .::..:.::: .. .: :: ::. ::
NP_004 VLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE9 LREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGML
::.::: :.:.::. .:: : :: . : : . .:: .: :. : ::.:
NP_004 LRQGLLDTSLTASVATLLAIAVERHRS-VMAVQLHSRLPRGRVVMLIVGVWVAALGLGLL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE9 PLLGWNCLCAFDRCSSLLPLYSKRYI----LFCLVIFAGVLATIMGLYGAIFRLVQASGQ
: .:.::::.:::: . :: :. :. : :..: ..:. .. . : :: ..
NP_004 PAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAE
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE9 KAP-RPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILA
.. .: :. . :.:::..:: ::.::: : .:: : .: . . . : ..:
NP_004 HVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCE--SCNVLAVEKYFLL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE9 LAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSS
:: :: :: .:: :. :. :. .:::.::: . : . . . :..::::
NP_004 LAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTR---ESVHYTSSAQGGASTRIML
290 300 310 320 330
360 370 380
pF1KE9 LRPRDSFRGSRSLSFRMREPLSSISSVRSI
NP_004 PENGHPLMDSTL
340 350
>>XP_016882957 (OMIM: 605110) PREDICTED: lysophosphatidi (351 aa)
initn: 588 init1: 233 opt: 622 Z-score: 567.8 bits: 113.7 E(85289): 6.9e-25
Smith-Waterman score: 622; 39.0% identity (64.0% similar) in 336 aa overlap (21-350:9-335)
10 20 30 40 50
pF1KE9 MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGR-LAGRGGPEDGGLGALRGLSVAASCL
... : . ::.::. :... :.: . :: ::.: : :
XP_016 MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVAL-GLTV--SVL
10 20 30 40
60 70 80 90 100 110
pF1KE9 VVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWF
:.: ::::.:::.:. : .. .:: : :.. .::..:.::: .. .: :: ::. ::
XP_016 VLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE9 LREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGML
::.::: :.:.::. .:: : :: . : : . .:: .: :. : ::.:
XP_016 LRQGLLDTSLTASVATLLAIAVERHRS-VMAVQLHSRLPRGRVVMLIVGVWVAALGLGLL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE9 PLLGWNCLCAFDRCSSLLPLYSKRYI----LFCLVIFAGVLATIMGLYGAIFRLVQASGQ
: .:.::::.:::: . :: :. :. : :..: ..:. .. . : :: ..
XP_016 PAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAE
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE9 KAP-RPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILA
.. .: :. . :.:::..:: ::.::: : .:: : .: . . . : ..:
XP_016 HVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCE--SCNVLAVEKYFLL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE9 LAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSS
:: :: :: .:: :. :. :. .:::.::: . : . . . :..::::
XP_016 LAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTR---ESVHYTSSAQGGASTRIML
290 300 310 320 330
360 370 380
pF1KE9 LRPRDSFRGSRSLSFRMREPLSSISSVRSI
XP_016 PENGHPLMDSTL
340 350
>>XP_011526723 (OMIM: 605110) PREDICTED: lysophosphatidi (351 aa)
initn: 588 init1: 233 opt: 622 Z-score: 567.8 bits: 113.7 E(85289): 6.9e-25
Smith-Waterman score: 622; 39.0% identity (64.0% similar) in 336 aa overlap (21-350:9-335)
10 20 30 40 50
pF1KE9 MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGR-LAGRGGPEDGGLGALRGLSVAASCL
... : . ::.::. :... :.: . :: ::.: : :
XP_011 MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVAL-GLTV--SVL
10 20 30 40
60 70 80 90 100 110
pF1KE9 VVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWF
:.: ::::.:::.:. : .. .:: : :.. .::..:.::: .. .: :: ::. ::
XP_011 VLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE9 LREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGML
::.::: :.:.::. .:: : :: . : : . .:: .: :. : ::.:
XP_011 LRQGLLDTSLTASVATLLAIAVERHRS-VMAVQLHSRLPRGRVVMLIVGVWVAALGLGLL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE9 PLLGWNCLCAFDRCSSLLPLYSKRYI----LFCLVIFAGVLATIMGLYGAIFRLVQASGQ
: .:.::::.:::: . :: :. :. : :..: ..:. .. . : :: ..
XP_011 PAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAE
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE9 KAP-RPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILA
.. .: :. . :.:::..:: ::.::: : .:: : .: . . . : ..:
XP_011 HVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCE--SCNVLAVEKYFLL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE9 LAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSS
:: :: :: .:: :. :. :. .:::.::: . : . . . :..::::
XP_011 LAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTR---ESVHYTSSAQGGASTRIML
290 300 310 320 330
360 370 380
pF1KE9 LRPRDSFRGSRSLSFRMREPLSSISSVRSI
XP_011 PENGHPLMDSTL
340 350
>>XP_016882958 (OMIM: 605110) PREDICTED: lysophosphatidi (351 aa)
initn: 588 init1: 233 opt: 622 Z-score: 567.8 bits: 113.7 E(85289): 6.9e-25
Smith-Waterman score: 622; 39.0% identity (64.0% similar) in 336 aa overlap (21-350:9-335)
10 20 30 40 50
pF1KE9 MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGR-LAGRGGPEDGGLGALRGLSVAASCL
... : . ::.::. :... :.: . :: ::.: : :
XP_016 MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVAL-GLTV--SVL
10 20 30 40
60 70 80 90 100 110
pF1KE9 VVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWF
:.: ::::.:::.:. : .. .:: : :.. .::..:.::: .. .: :: ::. ::
XP_016 VLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE9 LREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGML
::.::: :.:.::. .:: : :: . : : . .:: .: :. : ::.:
XP_016 LRQGLLDTSLTASVATLLAIAVERHRS-VMAVQLHSRLPRGRVVMLIVGVWVAALGLGLL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE9 PLLGWNCLCAFDRCSSLLPLYSKRYI----LFCLVIFAGVLATIMGLYGAIFRLVQASGQ
: .:.::::.:::: . :: :. :. : :..: ..:. .. . : :: ..
XP_016 PAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAE
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE9 KAP-RPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILA
.. .: :. . :.:::..:: ::.::: : .:: : .: . . . : ..:
XP_016 HVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCE--SCNVLAVEKYFLL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE9 LAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSS
:: :: :: .:: :. :. :. .:::.::: . : . . . :..::::
XP_016 LAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTR---ESVHYTSSAQGGASTRIML
290 300 310 320 330
360 370 380
pF1KE9 LRPRDSFRGSRSLSFRMREPLSSISSVRSI
XP_016 PENGHPLMDSTL
340 350
>>NP_110387 (OMIM: 605146) sphingosine 1-phosphate recep (398 aa)
initn: 816 init1: 346 opt: 610 Z-score: 556.7 bits: 111.8 E(85289): 2.9e-24
Smith-Waterman score: 824; 42.7% identity (67.1% similar) in 377 aa overlap (22-383:12-381)
10 20 30 40 50 60
pF1KE9 MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
:..::::::..:.: : .:: : . .:. ..
NP_110 MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFI
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
::::: :: .. : : . .. : ..::::::.:::: ::.:::: :..:.:: ::
NP_110 VLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
::: .:.::.::..::: : :: ::.: . . ... .:. .. . : .. :::.::
NP_110 REGGVFVALTASVLSLLAIALERSLTMARR-GPAPVSSRGRTLAMAAAAWGVSLLLGLLP
120 130 140 150 160
190 200 210 220 230
pF1KE9 LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAP-R
:::::: .: ::..::::.: :.:::.. :.:.::.: .::. :. :.:.... : :
NP_110 ALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPAR
170 180 190 200 210 220
240 250 260 270 280
pF1KE9 PA--------ARRKARRL--LKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGM
:. :::: : : :.:. ..::::..:::::: ::: :: . . :
NP_110 PGTAGTTSTRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDV-ACPARTCPVLLQA
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE9 DWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCL--ARAVEAHSG
: .:.::. :: .:::::.. .:.. .:.: ..::: : : :. : :.:: .:
NP_110 DPFLGLAMANSLLNPIIYTLTNRDLRHALLRLVCCGRHSCG-RDPSGSQQSASAAEASGG
290 300 310 320 330 340
350 360 370 380
pF1KE9 ASTTDSSLRP--RDSFRGSRSLSFRMREPLSSISSVRSI
: : :: ::. : .:. :.. .:. :
NP_110 LRRC---LPPGLDGSFSGSERSS-PQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
350 360 370 380 390
384 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:34:40 2016 done: Sun Nov 6 13:34:41 2016
Total Scan time: 7.630 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]