Result of FASTA (ccds) for
pFN21AE9462
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9462, 486 aa
1>>>pF1KE9462 486 - 486 aa - 486 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4239+/-0.000844; mu= 19.2341+/- 0.051
mean_var=94.5823+/-18.666, 0's: 0 Z-trim(110.0): 28 B-trim: 2 in 1/51
Lambda= 0.131877
statistics sampled from 11253 (11279) to 11253 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.346), width: 16
Scan time: 3.280
The best scores are: opt bits E(32554)
CCDS11699.1 GPRC5C gene_id:55890|Hs108|chr17 ( 486) 3301 638.2 5.8e-183
CCDS42378.1 GPRC5C gene_id:55890|Hs108|chr17 ( 453) 3061 592.5 3.1e-169
CCDS10581.1 GPRC5B gene_id:51704|Hs108|chr16 ( 403) 541 113.0 6.1e-25
CCDS8657.1 GPRC5A gene_id:9052|Hs108|chr12 ( 357) 478 101.0 2.3e-21
CCDS8658.1 GPRC5D gene_id:55507|Hs108|chr12 ( 345) 369 80.2 3.8e-15
>>CCDS11699.1 GPRC5C gene_id:55890|Hs108|chr17 (486 aa)
initn: 3301 init1: 3301 opt: 3301 Z-score: 3398.2 bits: 638.2 E(32554): 5.8e-183
Smith-Waterman score: 3301; 100.0% identity (100.0% similar) in 486 aa overlap (1-486:1-486)
10 20 30 40 50 60
pF1KE9 MRGRGSQQQQPTRRQGQKLPSPSPAGKYESAQPGGTQPEPGLGARMAIHKALVMCLGLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MRGRGSQQQQPTRRQGQKLPSPSPAGKYESAQPGGTQPEPGLGARMAIHKALVMCLGLPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 FLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLTIILVASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 FLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLTIILVASL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 PFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 AHVFALNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGSGEGGPQGNSSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AHVFALNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGSGEGGPQGNSSAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 WAVASPCAIANMDFVMALIYVMLLLLGAFLGAWPALCGRYKRWRKHGVFVLLTTATSVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 WAVASPCAIANMDFVMALIYVMLLLLGAFLGAWPALCGRYKRWRKHGVFVLLTTATSVAI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 WVVWIVMYTYGNKQHNSPTWDDPTLAIALAANAWAFVLFYVIPEVSQVTKSSPEQSYQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 WVVWIVMYTYGNKQHNSPTWDDPTLAIALAANAWAFVLFYVIPEVSQVTKSSPEQSYQGD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 MYPTRGVGYETILKEQKGQSMFVENKAFSMDEPVAAKRPVSPYSGYNGQLLTSVYQPTEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MYPTRGVGYETILKEQKGQSMFVENKAFSMDEPVAAKRPVSPYSGYNGQLLTSVYQPTEM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 ALMHKVPSEGAYDIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ALMHKVPSEGAYDIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFR
430 440 450 460 470 480
pF1KE9 NPYVWD
::::::
CCDS11 NPYVWD
>>CCDS42378.1 GPRC5C gene_id:55890|Hs108|chr17 (453 aa)
initn: 3061 init1: 3061 opt: 3061 Z-score: 3151.8 bits: 592.5 E(32554): 3.1e-169
Smith-Waterman score: 3061; 100.0% identity (100.0% similar) in 452 aa overlap (35-486:2-453)
10 20 30 40 50 60
pF1KE9 GSQQQQPTRRQGQKLPSPSPAGKYESAQPGGTQPEPGLGARMAIHKALVMCLGLPLFLFP
::::::::::::::::::::::::::::::
CCDS42 MGTQPEPGLGARMAIHKALVMCLGLPLFLFP
10 20 30
70 80 90 100 110 120
pF1KE9 GAWAQGHVPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLTIILVASLPFVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GAWAQGHVPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLTIILVASLPFVQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE9 DTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLAAHVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 DTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLAAHVF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE9 ALNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGSGEGGPQGNSSAGWAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 ALNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGSGEGGPQGNSSAGWAVA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE9 SPCAIANMDFVMALIYVMLLLLGAFLGAWPALCGRYKRWRKHGVFVLLTTATSVAIWVVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SPCAIANMDFVMALIYVMLLLLGAFLGAWPALCGRYKRWRKHGVFVLLTTATSVAIWVVW
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE9 IVMYTYGNKQHNSPTWDDPTLAIALAANAWAFVLFYVIPEVSQVTKSSPEQSYQGDMYPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 IVMYTYGNKQHNSPTWDDPTLAIALAANAWAFVLFYVIPEVSQVTKSSPEQSYQGDMYPT
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE9 RGVGYETILKEQKGQSMFVENKAFSMDEPVAAKRPVSPYSGYNGQLLTSVYQPTEMALMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 RGVGYETILKEQKGQSMFVENKAFSMDEPVAAKRPVSPYSGYNGQLLTSVYQPTEMALMH
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE9 KVPSEGAYDIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KVPSEGAYDIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPYV
400 410 420 430 440 450
pF1KE9 WD
::
CCDS42 WD
>>CCDS10581.1 GPRC5B gene_id:51704|Hs108|chr16 (403 aa)
initn: 944 init1: 534 opt: 541 Z-score: 561.3 bits: 113.0 E(32554): 6.1e-25
Smith-Waterman score: 945; 40.8% identity (68.9% similar) in 395 aa overlap (45-423:8-384)
20 30 40 50 60 70
pF1KE9 QGQKLPSPSPAGKYESAQPGGTQPEPGLGARMAIHKALVMCLGLPLFLFPGAWAQG-HVP
.: :..:.. : ::.. .. ... .
CCDS10 MFVASERKMRAHQVLTFLL---LFVITSVASENASTS
10 20 30
80 90 100 110 120 130
pF1KE9 PGCSQGLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLG
::. : : : .::: .. ::::.::::::: . :..: .::.. :::... .:.: .:
CCDS10 RGCGLDLLPQYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVRLPFIKEKEKKSPVG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE9 TQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLARKN
. .::::::::: :.:: ... : . :. ::::.:::::.::::: .... . :.:..
CCDS10 LHFLFLLGTLGLFGLTFAFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHG
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE9 HGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIANMD
:: :: . .:: : ::.::: .:::..:..: . : :: ::
CCDS10 TGPAGWQLVGLALCLMLVQVIIAVEWLVLTVLRDTR---PA------------CAYEPMD
160 170 180 190
260 270 280 290 300 310
pF1KE9 FVMALIYVMLLLLGAFLGAWPALCGRYKRWRKHGVFVLLTTATSVAIWVVWIVMYTYGN-
::::::: :.::. .. : .:::..:::. .:.:.:.:. :: :::.:..:: .::
CCDS10 FVMALIYDMVLLVVTLGLALFTLCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNV
200 210 220 230 240 250
320 330 340 350 360 370
pF1KE9 KQHNSPTWDDPTLAIALAANAWAFVLFYVIPEVSQVTKSSPEQSYQGDMYPTRGVGYETI
: ... .:.::::::.:::..:.::.:..:::. . . ... . . .. ::
CCDS10 KLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTLLPALQENTPNYFDTSQPRMRETA
260 270 280 290 300 310
380 390 400 410
pF1KE9 LKEQ-KGQSMFVENKAFSMDEPVAAKRPVSPYSGYNGQ-------------LLTSVYQPT
..:. . ..::::::::: :: : .. .: :. . ..:::::
CCDS10 FEEDVQLPRAYMENKAFSMDEHNAALRTAGFPNGSLGKRPSGSLGKRPSAPFRSNVYQPT
320 330 340 350 360 370
420 430 440 450 460 470
pF1KE9 EMALMHKVPSEGAYDIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQV
:::..
CCDS10 EMAVVLNGGTIPTAPPSHTGRHLW
380 390 400
>>CCDS8657.1 GPRC5A gene_id:9052|Hs108|chr12 (357 aa)
initn: 726 init1: 456 opt: 478 Z-score: 497.2 bits: 101.0 E(32554): 2.3e-21
Smith-Waterman score: 718; 38.5% identity (64.7% similar) in 374 aa overlap (72-441:5-342)
50 60 70 80 90 100
pF1KE9 LGARMAIHKALVMCLGLPLFLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGAWGIVLEAV
:: :: .::. :: :::.. :::::::.:
CCDS86 MATTVPDGCRNGLKSKYYRLCDKAEAWGIVLETV
10 20 30
110 120 130 140 150
pF1KE9 AGAGIVTT--FVLTI-ILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDF
: ::.::. :.::. ::: . :::...:..: :: .::::.::.: :.:: .. :
CCDS86 ATAGVVTSVAFMLTLPILVCK---VQDSNRRKMLPTQFLFLLGVLGIFGLTFAFIIGLDG
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE9 STCASRRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEVIINTE
:: .: ::::.::.:::::: ::. .:. :.: . ::. .:. ..::. .: :
CCDS86 STGPTRFFLFGILFSICFSCLLAHAVSLTKLVRGRKPLSLLVILGLAVGFSLVQDVIAIE
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE9 WLIITLVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAWPALCG
....:. : : .. ...: : :::. : ::..:. .:: . ..::
CCDS86 YIVLTMNRT--------NVNVFSELSAPRR--NEDFVLLLTYVLFLMALTFLMSSFTFCG
160 170 180 190 200
280 290 300 310 320 330
pF1KE9 RYKRWRKHGVFVLLTTATSVAIWVVWIVMYTYGNKQHNSPTWDDPTLAIALAANAWAFVL
. :..::. . :: :.::::.::.. . .. ::: :. :::::.:.:.:
CCDS86 SFTGWKRHGAHIYLTMLLSIAIWVAWITLLMLPDFDRR---WDDTILSSALAANGWVFLL
210 220 230 240 250
340 350 360 370 380 390
pF1KE9 FYVIPEVSQVTKSSPEQSYQGDMYPTRGVGYETILKEQK-GQSMFVENKAFSMDEPVAAK
:: :: .:: : : ::.. ... : : .:. :::.:.:..:
CCDS86 AYVSPEFWLLTK----QRNPMD-YPVE----DAFCKPQLVKKSYGVENRAYSQEE-----
260 270 280 290 300
400 410 420 430 440 450
pF1KE9 RPVSPYSGYNGQLLTSVYQPTEMALMHKVPSEGAYDIILPRATANSQVMGSANSTLRAED
.. .:. : . :. :.. :... :.. .. .::: :
CCDS86 --ITQGFEETGDTLYAPYS-THFQLQNQPPQK---EFSIPRAHAWPSPYKDYEVKKEGS
310 320 330 340 350
460 470 480
pF1KE9 MYSAQSHQAATPPKDGKNSQVFRNPYVWD
>>CCDS8658.1 GPRC5D gene_id:55507|Hs108|chr12 (345 aa)
initn: 663 init1: 369 opt: 369 Z-score: 385.3 bits: 80.2 E(32554): 3.8e-15
Smith-Waterman score: 686; 37.2% identity (67.2% similar) in 296 aa overlap (84-377:12-295)
60 70 80 90 100 110
pF1KE9 MCLGLPLFLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLT
:. ::: : :::.::..: :::.:..:
CCDS86 MYKDCIESTGDYFLLCDAEGPWGIILESLAILGIVVTILLL
10 20 30 40
120 130 140 150 160 170
pF1KE9 IILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFA
. .. . .:: .. ..: ::..:::..:::: :.:: ... . .: : ::::::::
CCDS86 LAFLFLMRKIQDCSQWNVLPTQLLFLLSVLGLFGLAFAFIIELNQQTAPVRYFLFGVLFA
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE9 ICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGSGEGGP
.::::: ::. : :.: . .:. .:. .:...:: ::.. . ..::
CCDS86 LCFSCLLAHASNLVKLVRGCVSFSWTTILCIAIGCSLLQIIIATEYVTLIMTRG------
110 120 130 140 150
240 250 260 270 280 290
pF1KE9 QGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAWPALCGRYKRWRKHGVFVLLT
.. .:: . :.:::. :.::..:. .:. . ..:: . :..:: ....:
CCDS86 -----MMFVNMTPCQL-NVDFVVLLVYVLFLMALTFFVSKATFCGPCENWKQHGRLIFIT
160 170 180 190 200
300 310 320 330 340 350
pF1KE9 TATSVAIWVVWIVMYTYGNKQ-HNSPTWDDPTLAIALAANAWAFVLFYVIPEVSQVTKSS
. :. :::::: : :: : . .: ::::.. :::..:::.:.:.:..::. . .:
CCDS86 VLFSIIIWVVWISMLLRGNPQFQRQPQWDDPVVCIALVTNAWVFLLLYIVPELCILYRSC
210 220 230 240 250 260
360 370 380 390 400 410
pF1KE9 -PEQSYQGDMYPTRGVGYETILKEQKGQSMFVENKAFSMDEPVAAKRPVSPYSGYNGQLL
: ::. :. . . ...:.
CCDS86 RQECPLQGNACPVTAYQHSFQVENQELSRARDSDGAEEDVALTSYGTPIQPQTVDPTQEC
270 280 290 300 310 320
486 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:50:20 2016 done: Mon Nov 7 03:50:20 2016
Total Scan time: 3.280 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]