Result of FASTA (omim) for
pFN21AE9437
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9437, 363 aa
1>>>pF1KE9437 363 - 363 aa - 363 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8364+/-0.000345; mu= 19.6736+/- 0.021
mean_var=89.6297+/-20.262, 0's: 0 Z-trim(115.4): 316 B-trim: 1398 in 1/49
Lambda= 0.135472
statistics sampled from 25393 (25796) to 25393 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.302), width: 16
Scan time: 8.210
The best scores are: opt bits E(85289)
NP_543009 (OMIM: 606921) G-protein coupled recepto ( 363) 2391 477.5 2.1e-134
NP_703143 (OMIM: 604847) G-protein coupled recepto ( 337) 1105 226.1 9.2e-59
NP_000862 (OMIM: 601109) 5-hydroxytryptamine recep ( 440) 307 70.2 9.7e-12
NP_955525 (OMIM: 602164) 5-hydroxytryptamine recep ( 378) 293 67.4 5.9e-11
NP_001035262 (OMIM: 602164) 5-hydroxytryptamine re ( 360) 290 66.8 8.5e-11
NP_001035259 (OMIM: 602164) 5-hydroxytryptamine re ( 387) 290 66.9 8.9e-11
NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388) 290 66.9 9e-11
NP_001273339 (OMIM: 602164) 5-hydroxytryptamine re ( 411) 290 66.9 9.3e-11
NP_001035263 (OMIM: 602164) 5-hydroxytryptamine re ( 428) 290 66.9 9.6e-11
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 273 63.6 9.6e-10
XP_011534457 (OMIM: 606915) PREDICTED: probable G- ( 419) 261 61.2 4.8e-09
XP_006715633 (OMIM: 606915) PREDICTED: probable G- ( 419) 261 61.2 4.8e-09
NP_110411 (OMIM: 606915) probable G-protein couple ( 419) 261 61.2 4.8e-09
XP_011534455 (OMIM: 606915) PREDICTED: probable G- ( 419) 261 61.2 4.8e-09
XP_011534456 (OMIM: 606915) PREDICTED: probable G- ( 419) 261 61.2 4.8e-09
XP_011534461 (OMIM: 606915) PREDICTED: probable G- ( 419) 261 61.2 4.8e-09
XP_011534459 (OMIM: 606915) PREDICTED: probable G- ( 419) 261 61.2 4.8e-09
NP_001137429 (OMIM: 606915) probable G-protein cou ( 419) 261 61.2 4.8e-09
XP_016866823 (OMIM: 606915) PREDICTED: probable G- ( 419) 261 61.2 4.8e-09
NP_009158 (OMIM: 604838) probable G-protein couple ( 372) 240 57.1 7.6e-08
NP_000785 (OMIM: 126449) D(1A) dopamine receptor [ ( 446) 240 57.2 8.6e-08
NP_000789 (OMIM: 126453,143465,606798) D(1B) dopam ( 477) 234 56.0 2e-07
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 229 54.9 3.5e-07
XP_011508789 (OMIM: 604153) PREDICTED: neuromedin- ( 403) 229 55.0 3.6e-07
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 229 55.0 3.7e-07
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 229 55.0 3.7e-07
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 229 55.0 3.7e-07
NP_006047 (OMIM: 604153) neuromedin-U receptor 1 [ ( 426) 229 55.0 3.7e-07
NP_000729 (OMIM: 118510) muscarinic acetylcholine ( 460) 227 54.6 5.1e-07
XP_011543044 (OMIM: 118510) PREDICTED: muscarinic ( 460) 227 54.6 5.1e-07
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 225 54.1 5.8e-07
NP_036257 (OMIM: 118496) muscarinic acetylcholine ( 532) 219 53.1 1.7e-06
NP_001307846 (OMIM: 118496) muscarinic acetylcholi ( 532) 219 53.1 1.7e-06
NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 217 52.6 1.7e-06
NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 217 52.6 1.7e-06
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic ( 408) 216 52.4 2.1e-06
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 213 51.8 2.9e-06
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362) 213 51.8 2.9e-06
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 213 51.8 3e-06
NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 213 51.8 3.1e-06
NP_001124527 (OMIM: 142703) histamine H2 receptor ( 397) 213 51.8 3.1e-06
NP_001265426 (OMIM: 102776) adenosine receptor A2a ( 412) 213 51.8 3.2e-06
NP_000666 (OMIM: 102776) adenosine receptor A2a [H ( 412) 213 51.8 3.2e-06
NP_001265429 (OMIM: 102776) adenosine receptor A2a ( 412) 213 51.8 3.2e-06
NP_001265427 (OMIM: 102776) adenosine receptor A2a ( 412) 213 51.8 3.2e-06
NP_001265428 (OMIM: 102776) adenosine receptor A2a ( 412) 213 51.8 3.2e-06
NP_612200 (OMIM: 609333) trace amine-associated re ( 339) 212 51.5 3.2e-06
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422) 213 51.9 3.2e-06
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422) 213 51.9 3.2e-06
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422) 213 51.9 3.2e-06
>>NP_543009 (OMIM: 606921) G-protein coupled receptor 78 (363 aa)
initn: 2391 init1: 2391 opt: 2391 Z-score: 2534.0 bits: 477.5 E(85289): 2.1e-134
Smith-Waterman score: 2391; 99.7% identity (99.7% similar) in 363 aa overlap (1-363:1-363)
10 20 30 40 50 60
pF1KE9 MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 PFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 PFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 RYAGLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 RYAGLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 FVLPLAVLCLTSLQVHRVARSHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHRAT
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
NP_543 FVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHRAT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 RKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLRRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 RKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLRRP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 FRQVLAGMVHRLLKRTPRPASTHDSSLDVAGMVHQLLKRTPRPASTHNGSVDTENDSCLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 FRQVLAGMVHRLLKRTPRPASTHDSSLDVAGMVHQLLKRTPRPASTHNGSVDTENDSCLQ
310 320 330 340 350 360
pF1KE9 QTH
:::
NP_543 QTH
>>NP_703143 (OMIM: 604847) G-protein coupled receptor 26 (337 aa)
initn: 1140 init1: 1094 opt: 1105 Z-score: 1176.0 bits: 226.1 E(85289): 9.2e-59
Smith-Waterman score: 1105; 52.3% identity (81.2% similar) in 329 aa overlap (1-327:1-323)
10 20 30 40 50 60
pF1KE9 MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDM
:. .: :::::: ...:.:::::::::: .::..: .: ... .::. :.:: ....:
NP_703 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 PFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRP
:.:: ::. : :.. :.. .:::::::.:. ::.:::: :.:.:: ::: : ...:
NP_703 PLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRL
70 80 90 100 110 120
130 140 150 160 170
pF1KE9 RYAGLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSL--RLPPEPERPRFAAFTATLHA
: :.:... .: ..:.: .:::. ::::. . .:::.: : : : : :::.::...::
NP_703 RDAALMVAYTWLHALTFPAAALALSWLGFHQLYASCTLCSRRPDE--RLRFAVFTGAFHA
130 140 150 160 170
180 190 200 210 220 230
pF1KE9 VGFVLPLAVLCLTSLQVHRVARSHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHR
..:.: ..::: : :.: .::: ::.:.:..::..:.::.:::::::.::: .:::::.:
NP_703 LSFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ATRKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLR
::.::. :.:::.::::::.:::.:: : ....::.:::::.::::..:::.:::::
NP_703 ATKKISTFIGTFLVCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE9 RPFRQVLAGMVHRLLKRTPRPASTHDSSLDVAGMVHQLLKRTPRPASTHNGSVDTENDSC
. .:. ...:::.: : :.:.:
NP_703 HQYRKSCKEILNRLLHRR----SIHSSGLTGDSHSQNILPVSE
300 310 320 330
>>NP_000862 (OMIM: 601109) 5-hydroxytryptamine receptor (440 aa)
initn: 193 init1: 149 opt: 307 Z-score: 331.7 bits: 70.2 E(85289): 9.7e-12
Smith-Waterman score: 307; 25.7% identity (57.0% similar) in 358 aa overlap (4-343:25-362)
10 20 30
pF1KE9 MGPGEALLAGLLVMVLAVALLSNALVL-LCCAYSAELRT
: . .:. : .:.:.. .:.:.. : :. : ::.
NP_000 MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPA-LRN
10 20 30 40 50
40 50 60 70 80 90
pF1KE9 RASGVLLVNLSLGHLLLAALDMPFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVA
.:. .::.: . :... . :: ..:... :: : : : . .:.. : . :..
NP_000 -TSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLC
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE9 ALSADQWLAVGFPLRYAGRLRP-RYAGLLLGCAWGQSLAFSGAALGCSW--LGYSSAFAS
.: :..: . :::: :. : : .:.:: ::. . : : .: ::..
NP_000 LISLDRYLLILSPLRYKLRMTPLRALALVLG-AWSLAALASFLPLLLGWHELGHAR----
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE9 CSLRLPPEPERPRF-AAFTATLHAVG--FVLPLAVLCLTSLQVHRVARSHCQRMDTVTM-
:: : . :. :.. .: : : : :: ...:.: .. .::.. .. ..:
NP_000 -----PPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTG
180 190 200 210 220
220 230 240 250 260
pF1KE9 ------KALALLADLHPSVR----QRCLIQQKRRRHRATRKIGIAIATFLICFAPYVMTR
..: . .:.:. .: ...:. .:. .:: .. :.. . :. ..
NP_000 MASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVAN
230 240 250 260 270 280
270 280 290 300 310 320
pF1KE9 LAELVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLRRPFRQVLAGMVHRLLKRTPRPAS
... : . . .:. : : ... .:. : :. : :...:. :.: : :
NP_000 IVQAVCDCISPGLFDVLTW-LGYCNSTMNPIIYPLFMRDFKRALG----RFL---PCPRC
290 300 310 320 330 340
330 340 350 360
pF1KE9 THDSSLDVAGMVHQLLKRTPRPASTHNGSVDTENDSCLQQTH
.. . ..:. . . :::
NP_000 PRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLL
350 360 370 380 390 400
>>NP_955525 (OMIM: 602164) 5-hydroxytryptamine receptor (378 aa)
initn: 176 init1: 102 opt: 293 Z-score: 317.7 bits: 67.4 E(85289): 5.9e-11
Smith-Waterman score: 293; 22.3% identity (56.9% similar) in 350 aa overlap (5-341:19-363)
10 20 30 40
pF1KE9 MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLV
...: .: :. .:.:.: ::.. .. .:: .. ..:
NP_955 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 NLSLGHLLLAALDMPFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWL
.:... ::...: ::: . ... . : : ::..:.. . . . .: :..
NP_955 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 AVGF-PLRYAGRLRPRYAGLLLGCAWGQSLAFSGAALGCSW--LGYSSAFASCSLRLPPE
:. :: : ... : .:.:: : .: . .: .: . . . .. .
NP_955 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 PERPRFAA---FTATLHAVGFVLPLAVLCLTSLQVHRVARSHCQRMDTVTMKALALLADL
: . .. : .:.: .:. .. :. ... .:. : .... . ..: : ..
NP_955 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ-MLQRAGAS-SES
190 200 210 220 230
230 240 250 260 270
pF1KE9 HPSVRQRCLIQQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELVPFV--TVNAQ-WGI
.:. .. .. : . .:.. . : .. : .:.::. .: ... ::. :: .: :
NP_955 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVD--PFIDYTVPGQVWTA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 LSKCLTYSKAVADPFTYSLLRRPFRQVLAGMVHRLLKRTPRPA----STHDSSLDVAGMV
. : : .. .:: :..: . ::... .. .: ::. .. :. . : .
NP_955 FLW-LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGST
300 310 320 330 340 350
340 350 360
pF1KE9 HQLLKRTPRPASTHNGSVDTENDSCLQQTH
: : .:
NP_955 HVLSGCSPVSSFLLLFCNRPVPV
360 370
>>NP_001035262 (OMIM: 602164) 5-hydroxytryptamine recept (360 aa)
initn: 176 init1: 102 opt: 290 Z-score: 314.8 bits: 66.8 E(85289): 8.5e-11
Smith-Waterman score: 290; 22.3% identity (57.1% similar) in 345 aa overlap (5-336:19-358)
10 20 30 40
pF1KE9 MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLV
...: .: :. .:.:.: ::.. .. .:: .. ..:
NP_001 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 NLSLGHLLLAALDMPFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWL
.:... ::...: ::: . ... . : : ::..:.. . . . .: :..
NP_001 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 AVGF-PLRYAGRLRPRYAGLLLGCAWGQSLAFSGAALGCSW--LGYSSAFASCSLRLPPE
:. :: : ... : .:.:: : .: . .: .: . . . .. .
NP_001 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 PERPRFAA---FTATLHAVGFVLPLAVLCLTSLQVHRVARSHCQRMDTVTMKALALLADL
: . .. : .:.: .:. .. :. ... .:. : .... . ..: : ..
NP_001 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ-MLQRAGAS-SES
190 200 210 220 230
230 240 250 260 270
pF1KE9 HPSVRQRCLIQQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELVPFV--TVNAQ-WGI
.:. .. .. : . .:.. . : .. : .:.::. .: ... ::. :: .: :
NP_001 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVD--PFIDYTVPGQVWTA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 LSKCLTYSKAVADPFTYSLLRRPFRQVLAGMVHRLLKRTPRPA----STHDSSLDVAGMV
. : : .. .:: :..: . ::... .. .: ::. .. :. . : .
NP_001 FLW-LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGST
300 310 320 330 340 350
340 350 360
pF1KE9 HQLLKRTPRPASTHNGSVDTENDSCLQQTH
: :
NP_001 HVLRF
360
>>NP_001035259 (OMIM: 602164) 5-hydroxytryptamine recept (387 aa)
initn: 176 init1: 102 opt: 290 Z-score: 314.4 bits: 66.9 E(85289): 8.9e-11
Smith-Waterman score: 290; 22.3% identity (57.1% similar) in 345 aa overlap (5-336:19-358)
10 20 30 40
pF1KE9 MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLV
...: .: :. .:.:.: ::.. .. .:: .. ..:
NP_001 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 NLSLGHLLLAALDMPFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWL
.:... ::...: ::: . ... . : : ::..:.. . . . .: :..
NP_001 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 AVGF-PLRYAGRLRPRYAGLLLGCAWGQSLAFSGAALGCSW--LGYSSAFASCSLRLPPE
:. :: : ... : .:.:: : .: . .: .: . . . .. .
NP_001 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 PERPRFAA---FTATLHAVGFVLPLAVLCLTSLQVHRVARSHCQRMDTVTMKALALLADL
: . .. : .:.: .:. .. :. ... .:. : .... . ..: : ..
NP_001 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ-MLQRAGAS-SES
190 200 210 220 230
230 240 250 260 270
pF1KE9 HPSVRQRCLIQQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELVPFV--TVNAQ-WGI
.:. .. .. : . .:.. . : .. : .:.::. .: ... ::. :: .: :
NP_001 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVD--PFIDYTVPGQVWTA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 LSKCLTYSKAVADPFTYSLLRRPFRQVLAGMVHRLLKRTPRPA----STHDSSLDVAGMV
. : : .. .:: :..: . ::... .. .: ::. .. :. . : .
NP_001 FLW-LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGST
300 310 320 330 340 350
340 350 360
pF1KE9 HQLLKRTPRPASTHNGSVDTENDSCLQQTH
: :
NP_001 HVLRYTVLHRGHHQELEKLPIHNDPESLESCF
360 370 380
>>NP_000861 (OMIM: 602164) 5-hydroxytryptamine receptor (388 aa)
initn: 176 init1: 102 opt: 290 Z-score: 314.4 bits: 66.9 E(85289): 9e-11
Smith-Waterman score: 290; 22.3% identity (57.1% similar) in 345 aa overlap (5-336:19-358)
10 20 30 40
pF1KE9 MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLV
...: .: :. .:.:.: ::.. .. .:: .. ..:
NP_000 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 NLSLGHLLLAALDMPFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWL
.:... ::...: ::: . ... . : : ::..:.. . . . .: :..
NP_000 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 AVGF-PLRYAGRLRPRYAGLLLGCAWGQSLAFSGAALGCSW--LGYSSAFASCSLRLPPE
:. :: : ... : .:.:: : .: . .: .: . . . .. .
NP_000 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 PERPRFAA---FTATLHAVGFVLPLAVLCLTSLQVHRVARSHCQRMDTVTMKALALLADL
: . .. : .:.: .:. .. :. ... .:. : .... . ..: : ..
NP_000 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ-MLQRAGAS-SES
190 200 210 220 230
230 240 250 260 270
pF1KE9 HPSVRQRCLIQQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELVPFV--TVNAQ-WGI
.:. .. .. : . .:.. . : .. : .:.::. .: ... ::. :: .: :
NP_000 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVD--PFIDYTVPGQVWTA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 LSKCLTYSKAVADPFTYSLLRRPFRQVLAGMVHRLLKRTPRPA----STHDSSLDVAGMV
. : : .. .:: :..: . ::... .. .: ::. .. :. . : .
NP_000 FLW-LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGST
300 310 320 330 340 350
340 350 360
pF1KE9 HQLLKRTPRPASTHNGSVDTENDSCLQQTH
: :
NP_000 HVLRDAVECGGQWESQCHPPATSPLVAAQPSDT
360 370 380
>>NP_001273339 (OMIM: 602164) 5-hydroxytryptamine recept (411 aa)
initn: 176 init1: 102 opt: 290 Z-score: 314.1 bits: 66.9 E(85289): 9.3e-11
Smith-Waterman score: 290; 22.3% identity (57.1% similar) in 345 aa overlap (5-336:19-358)
10 20 30 40
pF1KE9 MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLV
...: .: :. .:.:.: ::.. .. .:: .. ..:
NP_001 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 NLSLGHLLLAALDMPFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWL
.:... ::...: ::: . ... . : : ::..:.. . . . .: :..
NP_001 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 AVGF-PLRYAGRLRPRYAGLLLGCAWGQSLAFSGAALGCSW--LGYSSAFASCSLRLPPE
:. :: : ... : .:.:: : .: . .: .: . . . .. .
NP_001 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 PERPRFAA---FTATLHAVGFVLPLAVLCLTSLQVHRVARSHCQRMDTVTMKALALLADL
: . .. : .:.: .:. .. :. ... .:. : .... . ..: : ..
NP_001 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ-MLQRAGAS-SES
190 200 210 220 230
230 240 250 260 270
pF1KE9 HPSVRQRCLIQQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELVPFV--TVNAQ-WGI
.:. .. .. : . .:.. . : .. : .:.::. .: ... ::. :: .: :
NP_001 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVD--PFIDYTVPGQVWTA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 LSKCLTYSKAVADPFTYSLLRRPFRQVLAGMVHRLLKRTPRPA----STHDSSLDVAGMV
. : : .. .:: :..: . ::... .. .: ::. .. :. . : .
NP_001 FLW-LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGST
300 310 320 330 340 350
340 350 360
pF1KE9 HQLLKRTPRPASTHNGSVDTENDSCLQQTH
: :
NP_001 HVLSSGTETDRKKLWNKEEKIDQTIQMPKRKRKKKASLSYEDLILLGRKSCFREGK
360 370 380 390 400 410
>>NP_001035263 (OMIM: 602164) 5-hydroxytryptamine recept (428 aa)
initn: 176 init1: 102 opt: 290 Z-score: 313.9 bits: 66.9 E(85289): 9.6e-11
Smith-Waterman score: 290; 22.3% identity (57.1% similar) in 345 aa overlap (5-336:19-358)
10 20 30 40
pF1KE9 MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLV
...: .: :. .:.:.: ::.. .. .:: .. ..:
NP_001 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 NLSLGHLLLAALDMPFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWL
.:... ::...: ::: . ... . : : ::..:.. . . . .: :..
NP_001 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 AVGF-PLRYAGRLRPRYAGLLLGCAWGQSLAFSGAALGCSW--LGYSSAFASCSLRLPPE
:. :: : ... : .:.:: : .: . .: .: . . . .. .
NP_001 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 PERPRFAA---FTATLHAVGFVLPLAVLCLTSLQVHRVARSHCQRMDTVTMKALALLADL
: . .. : .:.: .:. .. :. ... .:. : .... . ..: : ..
NP_001 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ-MLQRAGAS-SES
190 200 210 220 230
230 240 250 260 270
pF1KE9 HPSVRQRCLIQQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELVPFV--TVNAQ-WGI
.:. .. .. : . .:.. . : .. : .:.::. .: ... ::. :: .: :
NP_001 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVD--PFIDYTVPGQVWTA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 LSKCLTYSKAVADPFTYSLLRRPFRQVLAGMVHRLLKRTPRPA----STHDSSLDVAGMV
. : : .. .:: :..: . ::... .. .: ::. .. :. . : .
NP_001 FLW-LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGST
300 310 320 330 340 350
340 350 360
pF1KE9 HQLLKRTPRPASTHNGSVDTENDSCLQQTH
: :
NP_001 HVLRTDFLFDRDILARYWTKPARAGPFSGTLSIRCLTARKPVLGDAVECGGQWESQCHPP
360 370 380 390 400 410
>>NP_937822 (OMIM: 606925) pyroglutamylated RFamide pept (431 aa)
initn: 88 init1: 67 opt: 273 Z-score: 295.9 bits: 63.6 E(85289): 9.6e-10
Smith-Waterman score: 273; 20.6% identity (57.5% similar) in 339 aa overlap (3-326:41-365)
10 20 30
pF1KE9 MGPGEALLAGLL--VMVLAVALLSNALVLLCC
::.: :: .: :...:.::..::::.
NP_937 FSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGNALVFYVV
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE9 AYSAELRTRASGVLLVNLSLGHLLLAALDMPFTLLGVMRGRTPSAPGACQVIGFLDTFLA
. : .:: ...... .:.:. ::.. . .: :.: . .. :... :... .
NP_937 TRSKAMRT-VTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAV
80 90 100 110 120
100 110 120 130 140 150
pF1KE9 SNAALSVAALSADQWLAVGFPLRYAGRLRPRYAGLLLGCAWGQSLAFSGAALGCSWLGYS
. :... ..... .. :... . : : .:: .: .. .. . : .
NP_937 VTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPMWHVQQLEIK
130 140 150 160 170 180
160 170 180 190 200
pF1KE9 SAFAS-----CSLRLPPEPERPRFAAFTATLHAVGFVLPLAVLCLTSLQVHRVARSHCQR
: : :. : . .. .:. . .. :.::: :. . .. . .
NP_937 YDFLYEKEHICCLEEWTSPVHQKI--YTTFILVILFLLPLMVMLILYSKIGYELWIKKRV
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE9 MDTVTMKALALLADLHPSVRQRCLIQQKRRRHRATRKIGIAIATFLICFAPY-VMTRLAE
: ... ... . . . :...::. . ..: : .:.::. :. . :
NP_937 GDGSVLR----------TIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIE
250 260 270 280 290
270 280 290 300 310
pF1KE9 LVPF------VTVNAQWGILSKCLTYSKAVADPFTYSLLRRPFRQ-VLAGMVHRLLKRTP
: ::.. ..:. . . .:... .:..:... . :.. ::... . ....:
NP_937 YSNFEKEYDDVTIKMIFAIV-QIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTF
300 310 320 330 340 350
320 330 340 350 360
pF1KE9 RPASTHDSSLDVAGMVHQLLKRTPRPASTHNGSVDTENDSCLQQTH
::. : .:
NP_937 SPAQRHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLAL
360 370 380 390 400 410
363 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:33:06 2016 done: Sun Nov 6 17:33:07 2016
Total Scan time: 8.210 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]