FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE9435, 617 aa
  1>>>pF1KE9435 617 - 617 aa - 617 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.8880+/-0.0013; mu= -1.4629+/- 0.078
 mean_var=288.0468+/-64.396, 0's: 0 Z-trim(109.9): 257  B-trim: 1249 in 2/49
 Lambda= 0.075569
 statistics sampled from 10881 (11238) to 10881 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.688), E-opt: 0.2 (0.345), width:  16
 Scan time:  3.740

The best scores are:                                      opt bits E(32554)
CCDS44012.1 GPR50 gene_id:9248|Hs108|chrX          ( 617) 4186 470.5 2.9e-132
CCDS3848.1 MTNR1A gene_id:4543|Hs108|chr4          ( 350) 1153 139.6 6.5e-33
CCDS8290.1 MTNR1B gene_id:4544|Hs108|chr11         ( 362) 1106 134.5 2.3e-31


>>CCDS44012.1 GPR50 gene_id:9248|Hs108|chrX               (617 aa)
 initn: 4186 init1: 4186 opt: 4186  Z-score: 2488.1  bits: 470.5 E(32554): 2.9e-132
Smith-Waterman score: 4186; 99.8% identity (100.0% similar) in 617 aa overlap (1-617:1-617)

               10        20        30        40        50        60
pF1KE9 MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 NSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 NSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 AIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 NYLNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 NYLNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 VIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNEN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE9 FRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARDQAREQDRAHACPAVEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARDQAREQDRAHACPAVEE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE9 TPMNVRNVPLPGDAAAGHPDRASGHPKPHSRSSSAYRKSASTHHKSVFSHSKAASGHLKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TPMNVRNVPLPGDAAAGHPDRASGHPKPHSRSSSAYRKSASTHHKSVFSHSKAASGHLKP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE9 VSGHSKPASGHPKSATVYPKPASVHFKADSVHFKGDSVHFKPDSVHFKPASSNPKPITGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VSGHSKPASGHPKSATVYPKPASVHFKADSVHFKGDSVHFKPDSVHFKPASSNPKPITGH
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE9 HVSAGSHSKSAFSAATSHPKPTTGHIKPATSHAEPTTADYPKPATTSHPKPTAADNPELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HVSAGSHSKSAFSAATSHPKPTTGHIKPATSHAEPTTADYPKPATTSHPKPTAADNPELS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE9 ASHCPEIPAIAHPVSDDSDLPESASSPAAGPTKPAASQLESDTIADLPDPTVVTTSTNDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ASHCPEIPAIAHPVSDDSDLPESASSPAAGPTKPAASQLESDTIADLPDPTVVTTSTNDY
              550       560       570       580       590       600

              610       
pF1KE9 HDVVVVDVEDDPDEMAV
       :::::.:::::::::::
CCDS44 HDVVVIDVEDDPDEMAV
              610       

>>CCDS3848.1 MTNR1A gene_id:4543|Hs108|chr4               (350 aa)
 initn: 1145 init1: 791 opt: 1153  Z-score: 704.4  bits: 139.6 E(32554): 6.5e-33
Smith-Waterman score: 1153; 51.5% identity (79.7% similar) in 305 aa overlap (24-326:23-327)

               10        20        30        40        50        60
pF1KE9 MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLR
                              :  :   . :....:::::..:: .:::.: .:::::
CCDS38  MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLR
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KE9 NSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIV
       :.::::::::.:::..::::::::.: ..  .::.:. :.::. ::. ::::.::::::.
CCDS38 NAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNIT
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KE9 AIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIF
       .:::::::::::::.:....: .:.  :... :..:. :::::.  ::..:::: :.: :
CCDS38 GIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTF
     120       130       140       150       160       170         

              190       200       210       220         230        
pF1KE9 NYLNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARD--PAGQNPDNQLAEVRNFLT
           . ..:...: .::..:..:: :::.:::  :: .:.     ..:  .  . :::.:
CCDS38 AQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVT
     180       190       200       210       220       230         

      240       250       260       270       280       290        
pF1KE9 MFVIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLN
       :::.:.:::.:: :.: . . :: .:  :. .::.::..:.:..:::::::::.::::::
CCDS38 MFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLN
     240       250       260       270       280       290         

      300       310       320       330       340       350        
pF1KE9 ENFRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARDQAREQDRAHACPAV
       .:::.::  :. ..    .::    .:.                                
CCDS38 QNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV         
     300       310       320       330       340       350         

>>CCDS8290.1 MTNR1B gene_id:4544|Hs108|chr11              (362 aa)
 initn: 1092 init1: 749 opt: 1106  Z-score: 676.5  bits: 134.5 E(32554): 2.3e-31
Smith-Waterman score: 1106; 48.3% identity (78.7% similar) in 315 aa overlap (6-315:17-329)

                          10         20        30        40        
pF1KE9            MGPTLAVPTPYGCIGCKLP-QPEYPPALIIFMFCAMVITIVVDLIGNSM
                       ::   ..  :   : .   :: .   .  ....: .::..:: .
CCDS82 MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
               10        20        30        40        50        60

       50        60        70        80        90       100        
pF1KE9 VILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFIT
       :::.: .:.::::.::.:.:::..::..::.:::::.: :.   :: :.. .:.  .:. 
CCDS82 VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
               70        80        90       100       110       120

      110       120       130       140       150       160        
pF1KE9 GLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGT
       ::::.::.:::.:::::::::::::. :.::.   .: ... . :..::.:.:::...:.
CCDS82 GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
              130       140       150       160       170       180

      170       180       190       200       210       220        
pF1KE9 IEYDPRTYTCIFNYLNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDN
       .::::: :.: :    .  .:...: :::.::. .:.:::.:::. :: ::  :  .:..
CCDS82 LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKA--KPES
              190       200       210       220       230          

      230           240       250       260       270       280    
pF1KE9 QL----AEVRNFLTMFVIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAY
       .:    ...:.::::::.:..::.:: :.: . . ::..:.::: .::. :....:..::
CCDS82 RLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAY
      240       250       260       270       280       290        

          290       300       310       320       330       340    
pF1KE9 FNSCLNAVIYGLLNENFRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARD
       :::::::..:::::.::::::  :. :. .:                             
CCDS82 FNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQ
      300       310       320       330       340       350        

          350       360       370       380       390       400    
pF1KE9 QAREQDRAHACPAVEETPMNVRNVPLPGDAAAGHPDRASGHPKPHSRSSSAYRKSASTHH
                                                                   
CCDS82 ADAL                                                        
      360                                                          




617 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 10:49:10 2016 done: Sun Nov  6 10:49:10 2016
 Total Scan time:  3.740 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]