Result of FASTA (omim) for
pFN21AE9434
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9434, 337 aa
1>>>pF1KE9434 337 - 337 aa - 337 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0955+/-0.000391; mu= 17.0638+/- 0.024
mean_var=89.1644+/-22.580, 0's: 0 Z-trim(111.4): 418 B-trim: 2263 in 2/51
Lambda= 0.135825
statistics sampled from 19447 (20042) to 19447 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.235), width: 16
Scan time: 6.860
The best scores are: opt bits E(85289)
NP_703143 (OMIM: 604847) G-protein coupled recepto ( 337) 2221 445.8 6.2e-125
NP_543009 (OMIM: 606921) G-protein coupled recepto ( 363) 1105 227.1 4.4e-59
NP_001035262 (OMIM: 602164) 5-hydroxytryptamine re ( 360) 319 73.1 1e-12
NP_955525 (OMIM: 602164) 5-hydroxytryptamine recep ( 378) 319 73.1 1.1e-12
NP_001035259 (OMIM: 602164) 5-hydroxytryptamine re ( 387) 319 73.1 1.1e-12
NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388) 319 73.1 1.1e-12
NP_001273339 (OMIM: 602164) 5-hydroxytryptamine re ( 411) 319 73.2 1.1e-12
NP_001035263 (OMIM: 602164) 5-hydroxytryptamine re ( 428) 319 73.2 1.2e-12
NP_612200 (OMIM: 609333) trace amine-associated re ( 339) 312 71.7 2.5e-12
NP_009158 (OMIM: 604838) probable G-protein couple ( 372) 289 67.2 6.2e-11
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 284 66.3 1.2e-10
XP_011508789 (OMIM: 604153) PREDICTED: neuromedin- ( 403) 261 61.8 2.9e-09
NP_006047 (OMIM: 604153) neuromedin-U receptor 1 [ ( 426) 261 61.8 3e-09
NP_000862 (OMIM: 601109) 5-hydroxytryptamine recep ( 440) 259 61.4 4.1e-09
XP_011534455 (OMIM: 606915) PREDICTED: probable G- ( 419) 256 60.8 5.9e-09
XP_011534456 (OMIM: 606915) PREDICTED: probable G- ( 419) 256 60.8 5.9e-09
XP_016866823 (OMIM: 606915) PREDICTED: probable G- ( 419) 256 60.8 5.9e-09
XP_011534461 (OMIM: 606915) PREDICTED: probable G- ( 419) 256 60.8 5.9e-09
NP_110411 (OMIM: 606915) probable G-protein couple ( 419) 256 60.8 5.9e-09
XP_011534459 (OMIM: 606915) PREDICTED: probable G- ( 419) 256 60.8 5.9e-09
XP_006715633 (OMIM: 606915) PREDICTED: probable G- ( 419) 256 60.8 5.9e-09
XP_011534457 (OMIM: 606915) PREDICTED: probable G- ( 419) 256 60.8 5.9e-09
NP_001137429 (OMIM: 606915) probable G-protein cou ( 419) 256 60.8 5.9e-09
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 239 57.5 6.2e-08
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 239 57.5 6.4e-08
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 235 56.8 1.1e-07
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 235 56.8 1.2e-07
XP_011543044 (OMIM: 118510) PREDICTED: muscarinic ( 460) 233 56.4 1.4e-07
NP_000729 (OMIM: 118510) muscarinic acetylcholine ( 460) 233 56.4 1.4e-07
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 232 56.1 1.6e-07
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 230 55.6 1.8e-07
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 228 55.3 2.7e-07
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 228 55.3 2.7e-07
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 228 55.4 3.1e-07
NP_009163 (OMIM: 604525) histamine H3 receptor [Ho ( 445) 227 55.2 3.2e-07
XP_005260323 (OMIM: 604525) PREDICTED: histamine H ( 453) 227 55.2 3.2e-07
XP_011507677 (OMIM: 612250) PREDICTED: G-protein c ( 529) 227 55.2 3.6e-07
XP_011507678 (OMIM: 612250) PREDICTED: G-protein c ( 529) 227 55.2 3.6e-07
XP_005245113 (OMIM: 612250) PREDICTED: G-protein c ( 529) 227 55.2 3.6e-07
XP_016856349 (OMIM: 612250) PREDICTED: G-protein c ( 529) 227 55.2 3.6e-07
XP_011507679 (OMIM: 612250) PREDICTED: G-protein c ( 529) 227 55.2 3.6e-07
XP_016856351 (OMIM: 612250) PREDICTED: G-protein c ( 529) 227 55.2 3.6e-07
NP_001254539 (OMIM: 612250) G-protein coupled rece ( 529) 227 55.2 3.6e-07
NP_722561 (OMIM: 612250) G-protein coupled recepto ( 529) 227 55.2 3.6e-07
XP_016856350 (OMIM: 612250) PREDICTED: G-protein c ( 529) 227 55.2 3.6e-07
XP_011507680 (OMIM: 612250) PREDICTED: G-protein c ( 529) 227 55.2 3.6e-07
XP_005245114 (OMIM: 612250) PREDICTED: G-protein c ( 529) 227 55.2 3.6e-07
NP_001254540 (OMIM: 612250) G-protein coupled rece ( 546) 227 55.3 3.6e-07
XP_016856348 (OMIM: 612250) PREDICTED: G-protein c ( 549) 227 55.3 3.7e-07
XP_005245112 (OMIM: 612250) PREDICTED: G-protein c ( 549) 227 55.3 3.7e-07
>>NP_703143 (OMIM: 604847) G-protein coupled receptor 26 (337 aa)
initn: 2221 init1: 2221 opt: 2221 Z-score: 2363.9 bits: 445.8 E(85289): 6.2e-125
Smith-Waterman score: 2221; 100.0% identity (100.0% similar) in 337 aa overlap (1-337:1-337)
10 20 30 40 50 60
pF1KE9 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 PLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 PLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 RDAALMVAYTWLHALTFPAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 RDAALMVAYTWLHALTFPAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 FLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 FLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRAT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 KKISTFIGTFLVCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 KKISTFIGTFLVCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQ
250 260 270 280 290 300
310 320 330
pF1KE9 YRKSCKEILNRLLHRRSIHSSGLTGDSHSQNILPVSE
:::::::::::::::::::::::::::::::::::::
NP_703 YRKSCKEILNRLLHRRSIHSSGLTGDSHSQNILPVSE
310 320 330
>>NP_543009 (OMIM: 606921) G-protein coupled receptor 78 (363 aa)
initn: 1140 init1: 1094 opt: 1105 Z-score: 1181.6 bits: 227.1 E(85289): 4.4e-59
Smith-Waterman score: 1105; 52.3% identity (81.2% similar) in 329 aa overlap (1-323:1-327)
10 20 30 40 50 60
pF1KE9 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNM
:. .: :::::: ...:.:::::::::: .::..: .: ... .::. :.:: ....:
NP_543 MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 PLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRL
:.:: ::. : :.. :.. .:::::::.:. ::.:::: :.:.:: ::: : ...:
NP_543 PFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRP
70 80 90 100 110 120
130 140 150 160 170
pF1KE9 RDAALMVAYTWLHALTFPAAALALSWLGFHQLYASCTLCSRRPDE--RLRFAVFTGAFHA
: :.:... .: ..:.: .:::. ::::. . .:::.: : : : : :::.::...::
NP_543 RYAGLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSL--RLPPEPERPRFAAFTATLHA
130 140 150 160 170
180 190 200 210 220 230
pF1KE9 LSFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQR
..:.: ..::: : :.: .::: ::.:.:..::..:.::.:::::::.::: .:::::.:
NP_543 VGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 ATKKISTFIGTFLVCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLR
::.::. :.:::.::::::.:::.:: : ....::.:::::.::::..:::.:::::
NP_543 ATRKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLR
240 250 260 270 280 290
300 310 320 330
pF1KE9 HQYRKSCKEILNRLLHRR----SIHSSGLTGDSHSQNILPVSE
. .:. ...:::.: : :.:.:
NP_543 RPFRQVLAGMVHRLLKRTPRPASTHDSSLDVAGMVHQLLKRTPRPASTHNGSVDTENDSC
300 310 320 330 340 350
>>NP_001035262 (OMIM: 602164) 5-hydroxytryptamine recept (360 aa)
initn: 178 init1: 107 opt: 319 Z-score: 349.3 bits: 73.1 E(85289): 1e-12
Smith-Waterman score: 319; 23.5% identity (58.1% similar) in 310 aa overlap (8-309:22-327)
10 20 30 40
pF1KE9 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTL
: .: .. ...:.: ::.. . . ..:. : .
NP_001 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 NLTCGNLLCTVVNMPLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWV
.:. ..:: .:. ::. .: . :. .: . . ::..:.. :.. . .:.::.
NP_001 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 AVVF-PLSYRAKMRLRDAALMVAYTWLHALTFPAAALALSW--LGFHQLYASCTLCSRRP
:. :: :: :: :::.. :. . . .: .:. .: . . .
NP_001 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 DERLRFAV---FTGAFHALSFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDL
. : : .. . ...: . :... .: .. .:. : ..:.. .: .
NP_001 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQM--LQRAGASSES
190 200 210 220 230
230 240 250 260 270
pF1KE9 HPSVRERCLEEQKRRRQRATKKISTFIGTFLVCFAPYVITRLVELF--STVPIGSHWGVL
.:. .. .. : . .:.: . ..: : .:.::. .: .:. : ::: :. : ..
NP_001 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVP-GQVWTAF
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 SKCLAYSKAASDPFVYSLLRHQYRKSCKEILNRLLHRRSIHSSGLTGDSHSQNILPVSE
:.: ... .::.:..: ...:.. ::
NP_001 LW-LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTH
300 310 320 330 340 350
NP_001 VLRF
360
>>NP_955525 (OMIM: 602164) 5-hydroxytryptamine receptor (378 aa)
initn: 178 init1: 107 opt: 319 Z-score: 349.0 bits: 73.1 E(85289): 1.1e-12
Smith-Waterman score: 319; 23.5% identity (58.1% similar) in 310 aa overlap (8-309:22-327)
10 20 30 40
pF1KE9 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTL
: .: .. ...:.: ::.. . . ..:. : .
NP_955 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 NLTCGNLLCTVVNMPLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWV
.:. ..:: .:. ::. .: . :. .: . . ::..:.. :.. . .:.::.
NP_955 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 AVVF-PLSYRAKMRLRDAALMVAYTWLHALTFPAAALALSW--LGFHQLYASCTLCSRRP
:. :: :: :: :::.. :. . . .: .:. .: . . .
NP_955 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 DERLRFAV---FTGAFHALSFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDL
. : : .. . ...: . :... .: .. .:. : ..:.. .: .
NP_955 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQM--LQRAGASSES
190 200 210 220 230
230 240 250 260 270
pF1KE9 HPSVRERCLEEQKRRRQRATKKISTFIGTFLVCFAPYVITRLVELF--STVPIGSHWGVL
.:. .. .. : . .:.: . ..: : .:.::. .: .:. : ::: :. : ..
NP_955 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVP-GQVWTAF
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 SKCLAYSKAASDPFVYSLLRHQYRKSCKEILNRLLHRRSIHSSGLTGDSHSQNILPVSE
:.: ... .::.:..: ...:.. ::
NP_955 LW-LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTH
300 310 320 330 340 350
NP_955 VLSGCSPVSSFLLLFCNRPVPV
360 370
>>NP_001035259 (OMIM: 602164) 5-hydroxytryptamine recept (387 aa)
initn: 178 init1: 107 opt: 319 Z-score: 348.9 bits: 73.1 E(85289): 1.1e-12
Smith-Waterman score: 319; 23.5% identity (58.1% similar) in 310 aa overlap (8-309:22-327)
10 20 30 40
pF1KE9 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTL
: .: .. ...:.: ::.. . . ..:. : .
NP_001 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 NLTCGNLLCTVVNMPLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWV
.:. ..:: .:. ::. .: . :. .: . . ::..:.. :.. . .:.::.
NP_001 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 AVVF-PLSYRAKMRLRDAALMVAYTWLHALTFPAAALALSW--LGFHQLYASCTLCSRRP
:. :: :: :: :::.. :. . . .: .:. .: . . .
NP_001 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 DERLRFAV---FTGAFHALSFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDL
. : : .. . ...: . :... .: .. .:. : ..:.. .: .
NP_001 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQM--LQRAGASSES
190 200 210 220 230
230 240 250 260 270
pF1KE9 HPSVRERCLEEQKRRRQRATKKISTFIGTFLVCFAPYVITRLVELF--STVPIGSHWGVL
.:. .. .. : . .:.: . ..: : .:.::. .: .:. : ::: :. : ..
NP_001 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVP-GQVWTAF
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 SKCLAYSKAASDPFVYSLLRHQYRKSCKEILNRLLHRRSIHSSGLTGDSHSQNILPVSE
:.: ... .::.:..: ...:.. ::
NP_001 LW-LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTH
300 310 320 330 340 350
NP_001 VLRYTVLHRGHHQELEKLPIHNDPESLESCF
360 370 380
>>NP_000861 (OMIM: 602164) 5-hydroxytryptamine receptor (388 aa)
initn: 178 init1: 107 opt: 319 Z-score: 348.9 bits: 73.1 E(85289): 1.1e-12
Smith-Waterman score: 319; 23.5% identity (58.1% similar) in 310 aa overlap (8-309:22-327)
10 20 30 40
pF1KE9 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTL
: .: .. ...:.: ::.. . . ..:. : .
NP_000 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 NLTCGNLLCTVVNMPLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWV
.:. ..:: .:. ::. .: . :. .: . . ::..:.. :.. . .:.::.
NP_000 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 AVVF-PLSYRAKMRLRDAALMVAYTWLHALTFPAAALALSW--LGFHQLYASCTLCSRRP
:. :: :: :: :::.. :. . . .: .:. .: . . .
NP_000 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 DERLRFAV---FTGAFHALSFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDL
. : : .. . ...: . :... .: .. .:. : ..:.. .: .
NP_000 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQM--LQRAGASSES
190 200 210 220 230
230 240 250 260 270
pF1KE9 HPSVRERCLEEQKRRRQRATKKISTFIGTFLVCFAPYVITRLVELF--STVPIGSHWGVL
.:. .. .. : . .:.: . ..: : .:.::. .: .:. : ::: :. : ..
NP_000 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVP-GQVWTAF
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 SKCLAYSKAASDPFVYSLLRHQYRKSCKEILNRLLHRRSIHSSGLTGDSHSQNILPVSE
:.: ... .::.:..: ...:.. ::
NP_000 LW-LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTH
300 310 320 330 340 350
NP_000 VLRDAVECGGQWESQCHPPATSPLVAAQPSDT
360 370 380
>>NP_001273339 (OMIM: 602164) 5-hydroxytryptamine recept (411 aa)
initn: 178 init1: 107 opt: 319 Z-score: 348.6 bits: 73.2 E(85289): 1.1e-12
Smith-Waterman score: 319; 23.5% identity (58.1% similar) in 310 aa overlap (8-309:22-327)
10 20 30 40
pF1KE9 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTL
: .: .. ...:.: ::.. . . ..:. : .
NP_001 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 NLTCGNLLCTVVNMPLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWV
.:. ..:: .:. ::. .: . :. .: . . ::..:.. :.. . .:.::.
NP_001 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 AVVF-PLSYRAKMRLRDAALMVAYTWLHALTFPAAALALSW--LGFHQLYASCTLCSRRP
:. :: :: :: :::.. :. . . .: .:. .: . . .
NP_001 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 DERLRFAV---FTGAFHALSFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDL
. : : .. . ...: . :... .: .. .:. : ..:.. .: .
NP_001 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQM--LQRAGASSES
190 200 210 220 230
230 240 250 260 270
pF1KE9 HPSVRERCLEEQKRRRQRATKKISTFIGTFLVCFAPYVITRLVELF--STVPIGSHWGVL
.:. .. .. : . .:.: . ..: : .:.::. .: .:. : ::: :. : ..
NP_001 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVP-GQVWTAF
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 SKCLAYSKAASDPFVYSLLRHQYRKSCKEILNRLLHRRSIHSSGLTGDSHSQNILPVSE
:.: ... .::.:..: ...:.. ::
NP_001 LW-LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTH
300 310 320 330 340 350
NP_001 VLSSGTETDRKKLWNKEEKIDQTIQMPKRKRKKKASLSYEDLILLGRKSCFREGK
360 370 380 390 400 410
>>NP_001035263 (OMIM: 602164) 5-hydroxytryptamine recept (428 aa)
initn: 178 init1: 107 opt: 319 Z-score: 348.4 bits: 73.2 E(85289): 1.2e-12
Smith-Waterman score: 319; 23.5% identity (58.1% similar) in 310 aa overlap (8-309:22-327)
10 20 30 40
pF1KE9 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTL
: .: .. ...:.: ::.. . . ..:. : .
NP_001 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 NLTCGNLLCTVVNMPLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWV
.:. ..:: .:. ::. .: . :. .: . . ::..:.. :.. . .:.::.
NP_001 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 AVVF-PLSYRAKMRLRDAALMVAYTWLHALTFPAAALALSW--LGFHQLYASCTLCSRRP
:. :: :: :: :::.. :. . . .: .:. .: . . .
NP_001 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 DERLRFAV---FTGAFHALSFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDL
. : : .. . ...: . :... .: .. .:. : ..:.. .: .
NP_001 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQM--LQRAGASSES
190 200 210 220 230
230 240 250 260 270
pF1KE9 HPSVRERCLEEQKRRRQRATKKISTFIGTFLVCFAPYVITRLVELF--STVPIGSHWGVL
.:. .. .. : . .:.: . ..: : .:.::. .: .:. : ::: :. : ..
NP_001 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVP-GQVWTAF
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE9 SKCLAYSKAASDPFVYSLLRHQYRKSCKEILNRLLHRRSIHSSGLTGDSHSQNILPVSE
:.: ... .::.:..: ...:.. ::
NP_001 LW-LGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTH
300 310 320 330 340 350
NP_001 VLRTDFLFDRDILARYWTKPARAGPFSGTLSIRCLTARKPVLGDAVECGGQWESQCHPPA
360 370 380 390 400 410
>>NP_612200 (OMIM: 609333) trace amine-associated recept (339 aa)
initn: 99 init1: 74 opt: 312 Z-score: 342.2 bits: 71.7 E(85289): 2.5e-12
Smith-Waterman score: 312; 23.5% identity (58.2% similar) in 328 aa overlap (2-317:16-328)
10 20 30 40
pF1KE9 MNSWD----AGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPA
:.:. :.: .:.: . ..:..: .:.. . : ... .
NP_612 MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNW
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 LFTLNLTCGNLL-CTVVNMPLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALS
:. : :: : : :: ... . . :. .:.. . : .:.. :.. .. .:
NP_612 LIHSMATVDFLLGCLV--MPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFIS
70 80 90 100 110
110 120 130 140 150
pF1KE9 IDRWVAVVFPLSYRAKMRLRDAALMVAYTWL--HALTFPAAALALSWLGFHQLYASCTLC
:::. :: :: :.::: . .:. .: ...: : :.. : ...: . . :
NP_612 IDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHC
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE9 SRRPDERLRFAVFTGAFHALSFLLSFVV----LCCTYLKVLKVARFHCKRIDVITMQTLV
: . :. ..:. :.:. :: . . :.: .. .:. . . :. . : :
NP_612 --RGGCSVFFSKISGV---LTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDAN-QKLQ
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE9 LLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFLVCFAPYVITRLVELFSTVPIGSHW
. .... .. :...: .:.: .. .:.::.:. :. : ... : :
NP_612 IGLEMKNGIS------QSKER-KAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTL
240 250 260 270 280
280 290 300 310 320 330
pF1KE9 GVLSKCLAYSKAASDPFVYSLLRHQYRKSCKEIL-NRLLHRRSIHSSGLTGDSHSQNILP
. . ..: ... .:.::... .::. : .: ...... :
NP_612 NDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
290 300 310 320 330
pF1KE9 VSE
>>NP_009158 (OMIM: 604838) probable G-protein coupled re (372 aa)
initn: 154 init1: 106 opt: 289 Z-score: 317.3 bits: 67.2 E(85289): 6.2e-11
Smith-Waterman score: 289; 25.5% identity (57.9% similar) in 321 aa overlap (8-309:37-339)
10 20 30
pF1KE9 MNSWDAGLAGLLVGTMGVSLLSNALVLLCLL-HSADI
:: ... :..:.:..: :.. ..
NP_009 SLEAYTYLLLNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVV--CIIVYQRPA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE9 RRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLS
:.: :. .:. .... .. ::.: . ... : ::..:::.: : :.. ...
NP_009 MRSAINLLLATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE9 MAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTWLHALTFPAAALALSWLGFHQLYASC
. .:.::.. .: . . :. : : ...: .:. :.: :. .:. . .. :
NP_009 LLIISVDRFLIIV---QRQDKLNPRRAKVIIAVSWV--LSFCIAGPSLTGWTLVEVPARA
130 140 150 160 170
160 170 180 190 200 210
pF1KE9 TLC----SRRPDERLRFAVFTGAFHALSFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQ
: .. : .: .... : :. : :. :.:. .:...: . :. :
NP_009 PQCVLGYTELPADRAYVVTLVVAV----FFAPFGVMLCAYMCILNTVRKNAVRVH---NQ
180 190 200 210 220 230
220 230 240 250 260
pF1KE9 TLVLLVDLHPSVRERCLEEQKRRRQRA------TKKIST----FIGTFLVCFAPYVITRL
. : ::. .: :.. .:..: . :: ..: :.: : .:. :. . :
NP_009 SDSL--DLRQLTRAG-LRRLQRQQQVSVDLSFKTKAFTTILILFVG-FSLCWLPHSVYSL
240 250 260 270 280
270 280 290 300 310
pF1KE9 VELFST-VPIGSHWGVLSKC---LAYSKAASDPFVYSLLRHQYRKSCKEILNRLLHRRSI
. .:: :: . . : : :.: :.. .:.:: ...:..: :.:
NP_009 LSVFSQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELLPQTFQILPK
290 300 310 320 330 340
320 330
pF1KE9 HSSGLTGDSHSQNILPVSE
NP_009 VPERIRRRIQPSTVYVCNENQSAV
350 360 370
337 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:19:16 2016 done: Sun Nov 6 15:19:17 2016
Total Scan time: 6.860 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]