Result of FASTA (omim) for
pFN21AE9421
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9421, 348 aa
1>>>pF1KE9421 348 - 348 aa - 348 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7452+/-0.000512; mu= 19.9423+/- 0.032
mean_var=137.4852+/-35.893, 0's: 0 Z-trim(110.2): 576 B-trim: 1233 in 1/50
Lambda= 0.109382
statistics sampled from 17700 (18471) to 17700 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.567), E-opt: 0.2 (0.217), width: 16
Scan time: 5.980
The best scores are: opt bits E(85289)
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 2320 378.5 1.2e-104
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 1690 279.1 1e-74
NP_444508 (OMIM: 606927) trace amine-associated re ( 342) 1625 268.8 1.2e-71
NP_003958 (OMIM: 607405) trace amine-associated re ( 337) 1052 178.4 2e-44
NP_612200 (OMIM: 609333) trace amine-associated re ( 339) 983 167.5 3.8e-41
NP_001028252 (OMIM: 604849) trace amine-associated ( 351) 886 152.2 1.6e-36
NP_055441 (OMIM: 604849) trace amine-associated re ( 306) 849 146.3 8.4e-35
NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413) 434 81.0 5.1e-15
NP_001035262 (OMIM: 602164) 5-hydroxytryptamine re ( 360) 421 78.9 2e-14
NP_955525 (OMIM: 602164) 5-hydroxytryptamine recep ( 378) 421 78.9 2e-14
NP_001035259 (OMIM: 602164) 5-hydroxytryptamine re ( 387) 421 78.9 2e-14
NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388) 421 78.9 2e-14
NP_001273339 (OMIM: 602164) 5-hydroxytryptamine re ( 411) 421 78.9 2.1e-14
NP_001035263 (OMIM: 602164) 5-hydroxytryptamine re ( 428) 421 79.0 2.1e-14
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308) 409 76.9 6.7e-14
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317) 409 76.9 6.8e-14
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324) 409 76.9 6.9e-14
NP_001309433 (OMIM: 104221) alpha-1A adrenergic re ( 342) 409 76.9 7.1e-14
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370) 409 77.0 7.4e-14
NP_001309431 (OMIM: 104221) alpha-1A adrenergic re ( 372) 409 77.0 7.4e-14
XP_006716356 (OMIM: 104221) PREDICTED: alpha-1A ad ( 429) 409 77.1 7.9e-14
NP_150645 (OMIM: 104221) alpha-1A adrenergic recep ( 429) 409 77.1 7.9e-14
NP_150647 (OMIM: 104221) alpha-1A adrenergic recep ( 455) 409 77.1 8.2e-14
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465) 409 77.1 8.3e-14
NP_000671 (OMIM: 104221) alpha-1A adrenergic recep ( 466) 409 77.1 8.3e-14
XP_006716355 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 409 77.2 8.4e-14
XP_016868584 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 409 77.2 8.4e-14
NP_150646 (OMIM: 104221) alpha-1A adrenergic recep ( 475) 409 77.2 8.4e-14
XP_016868583 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475) 409 77.2 8.4e-14
NP_000674 (OMIM: 104250) alpha-2C adrenergic recep ( 462) 408 77.0 9.2e-14
NP_000673 (OMIM: 104260,607876) alpha-2B adrenergi ( 450) 407 76.8 1e-13
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 405 76.3 1.1e-13
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362) 405 76.3 1.1e-13
NP_001124527 (OMIM: 142703) histamine H2 receptor ( 397) 405 76.4 1.2e-13
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422) 405 76.4 1.2e-13
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422) 405 76.4 1.2e-13
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422) 405 76.4 1.2e-13
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422) 405 76.4 1.2e-13
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422) 405 76.4 1.2e-13
NP_001265426 (OMIM: 102776) adenosine receptor A2a ( 412) 401 75.8 1.9e-13
NP_000666 (OMIM: 102776) adenosine receptor A2a [H ( 412) 401 75.8 1.9e-13
NP_001265428 (OMIM: 102776) adenosine receptor A2a ( 412) 401 75.8 1.9e-13
NP_001265427 (OMIM: 102776) adenosine receptor A2a ( 412) 401 75.8 1.9e-13
NP_001265429 (OMIM: 102776) adenosine receptor A2a ( 412) 401 75.8 1.9e-13
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390) 386 73.4 9.4e-13
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 366 70.4 9.3e-12
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 366 70.4 9.8e-12
NP_000785 (OMIM: 126449) D(1A) dopamine receptor [ ( 446) 364 70.0 1.1e-11
NP_000855 (OMIM: 182133) 5-hydroxytryptamine recep ( 377) 360 69.3 1.6e-11
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328) 357 68.7 2e-11
>>NP_778227 (OMIM: 608282) trace amine-associated recept (348 aa)
initn: 2320 init1: 2320 opt: 2320 Z-score: 1999.8 bits: 378.5 E(85289): 1.2e-104
Smith-Waterman score: 2320; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:1-348)
10 20 30 40 50 60
pF1KE9 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV
250 260 270 280 290 300
310 320 330 340
pF1KE9 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
310 320 330 340
>>NP_778237 (OMIM: 608923) trace amine-associated recept (345 aa)
initn: 1711 init1: 1682 opt: 1690 Z-score: 1462.6 bits: 279.1 E(85289): 1e-74
Smith-Waterman score: 1690; 69.0% identity (89.0% similar) in 345 aa overlap (1-345:1-345)
10 20 30 40 50 60
pF1KE9 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF
: .: : ::.::: ::: ::.: :.::: : ::: :.:::::::.::::::::.::::
NP_778 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL
::::.:::::.:::::::::::::::::: ::.:::::::: :.: :::: :..::..::
NP_778 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL
:::: ::.::::::::::.:::::::::::::: .::.. . :: ..::::. ..:.:::
NP_778 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS
::.:.::::. .:::::: :: ::::. :...:..:::::..::.:::.:.:...:
NP_778 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV
:::::: :::.::::::::::....::..::::: .:..:::.:.:::: .::: ::.
NP_778 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA
250 260 270 280 290 300
310 320 330 340
pF1KE9 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
::::::::::::.:: :: ::::.::.:.::...:.: :::::..
NP_778 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
310 320 330 340
>>NP_444508 (OMIM: 606927) trace amine-associated recept (342 aa)
initn: 1657 init1: 1596 opt: 1625 Z-score: 1407.2 bits: 268.8 E(85289): 1.2e-71
Smith-Waterman score: 1625; 67.6% identity (89.8% similar) in 343 aa overlap (1-343:1-342)
10 20 30 40 50 60
pF1KE9 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF
:..:::: .:.:::..:: :::.:::::: : :::....::..::.::::::: ..:::
NP_444 MTSNFSQP-VVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHF
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL
::::.::::::::::::::::::::: :: ::.:::::::: ..: .:.: :..::..:.
NP_444 KQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL
.::: : .::::.:::::.: :::::::::::: .::.. .::: ..::::.:..:.:::
NP_444 LHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEEL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS
: ::.:::::: ..:.:::. :::::::...:...::::::.::.:: :::.:.:...:
NP_444 VSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVES
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE9 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV
:::::: ::::::::::::::... ::..::::: :: .:::.:.:.:: :.::: : .
NP_444 SSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSA
240 250 260 270 280 290
310 320 330 340
pF1KE9 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
::::::::::::.:: :: ::::::.:: ::...::: .:: :
NP_444 YYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
300 310 320 330 340
>>NP_003958 (OMIM: 607405) trace amine-associated recept (337 aa)
initn: 1100 init1: 690 opt: 1052 Z-score: 918.6 bits: 178.4 E(85289): 2e-44
Smith-Waterman score: 1052; 46.2% identity (75.5% similar) in 331 aa overlap (13-343:16-337)
10 20 30 40 50
pF1KE9 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAI
.::. :: :: .: .. : . ..: . . : .. ..::..: .:.
NP_003 MRAVFIQGAEEHPAAFCYQ-VNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAV
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 LHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCF
.:: ::::::::. ::: ::...:. :.:.::.:::::::.::: :..:: .:: ::.
NP_003 SYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 ASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGI
.:.:::: ::.::. :. ::: ::.:::: :. :. .: ..:. ..:: . : .
NP_003 TSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 EELVVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQ
. . . :::.:: ::. : : : :::.: . :. .: :::.:: .::..: .: :.
NP_003 SQWLEEMPCVGSCQLLLNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQI-TTLSK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 AQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILV
. ... ::.:::::::::::.. .:. :::. .:...:. ..::::: :..:..
NP_003 SLAGA-------AKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFI
240 250 260 270 280 290
300 310 320 330 340
pF1KE9 WCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
: .:.::: ::.::.: :::: ::.:: .: ::. .. :..:..:
NP_003 WFAYFNSACNPIIYVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE
300 310 320 330
>>NP_612200 (OMIM: 609333) trace amine-associated recept (339 aa)
initn: 981 init1: 512 opt: 983 Z-score: 859.7 bits: 167.5 E(85289): 3.8e-41
Smith-Waterman score: 983; 42.8% identity (73.1% similar) in 334 aa overlap (13-343:4-336)
10 20 30 40 50 60
pF1KE9 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF
.:.. .: ::.:. .: :. ::... . . . :::.:...: ::
NP_612 MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHF
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL
::::::::.:: :.: .:::.: :::.: :::.: :::::. .::.:: : . ::.
NP_612 KQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL
::: ::.::: :: ::: : .:... : . : .:: ....:.... : .: ::.
NP_612 FHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEI
120 130 140 150 160 170
190 200 210 220 230
pF1KE9 VVA-LTCVGGCQAPLNQNWVLLCFLL-FFIPNVAMVFIYSKIFLVAKHQARKIESTASQA
. : :::.. ... .: :. :.::. :. .: .:.:.::.::: : : :.:
NP_612 YYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLI-SDANQK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 QSSSESYKERVAK-RERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILV
. . .:. ... .::::.:::::.:..::. : :... .:.: ....: :: . ..:.
NP_612 LQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLI
240 250 260 270 280 290
300 310 320 330 340
pF1KE9 WCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
: : ::..::..::::: :: ::.:... ::... ::: .:: :
NP_612 WFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
300 310 320 330
>>NP_001028252 (OMIM: 604849) trace amine-associated rec (351 aa)
initn: 882 init1: 551 opt: 886 Z-score: 776.8 bits: 152.2 E(85289): 1.6e-36
Smith-Waterman score: 886; 40.2% identity (70.1% similar) in 321 aa overlap (14-333:25-337)
10 20 30 40
pF1KE9 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFG
: . :.:: .. : : : .:. .. . .. ::
NP_001 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE9 NLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHT
:: ..:.: .:::::::::::: :.: .:::.: :.::.: .::::.::::: ..::..
NP_001 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE9 CFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFY
:: . ..:.:::: ...::. :. :: : ::.:. : ..: : ...:.. .
NP_001 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE9 TGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLL-FFIPNVAMVFIYSKIFLVAKHQA
. : .::: . ..: ..: . .:. : :. :: :. :: ::.::: :....:
NP_001 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE9 RKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFIT
. :.. :. ...: :...::::::::....::. :.: . ..: ..:: :
NP_001 HAINNL-------RENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFST
250 260 270 280 290
290 300 310 320 330 340
pF1KE9 PPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
: ... :.: :.::. :::::.::: :: .:.: :. ::.. .
NP_001 PVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
300 310 320 330 340 350
>>NP_055441 (OMIM: 604849) trace amine-associated recept (306 aa)
initn: 843 init1: 512 opt: 849 Z-score: 745.8 bits: 146.3 E(85289): 8.4e-35
Smith-Waterman score: 849; 40.7% identity (71.3% similar) in 300 aa overlap (35-333:1-292)
10 20 30 40 50 60
pF1KE9 FSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLH
.:. .. . .. :::: ..:.: .:::::
NP_055 MYSFMAGSIFITIFGNLAMIISISYFKQLH
10 20 30
70 80 90 100 110 120
pF1KE9 TPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLC
::::::: :.: .:::.: :.::.: .::::.::::: ..::.. :: . ..:.::::
NP_055 TPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLC
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE9 CISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVAL
...::. :. :: : ::.:. : ..: : ...:.. .. : .::: . .
NP_055 SVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE9 TCVGGCQAPLNQNWVLLCFLL-FFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSE
.: ..: . .:. : :. :: :. :: ::.::: :....:. :.. :
NP_055 ACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNL-------RE
160 170 180 190 200
250 260 270 280 290 300
pF1KE9 SYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYN
. ...: :...::::::::....::. :.: . ..: ..:: :: ... :.: :.:
NP_055 NQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFN
210 220 230 240 250 260
310 320 330 340
pF1KE9 SAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
:. :::::.::: :: .:.: :. ::.. .
NP_055 STCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
270 280 290 300
>>NP_000015 (OMIM: 109690,600807,601665) beta-2 adrenerg (413 aa)
initn: 548 init1: 328 opt: 434 Z-score: 390.7 bits: 81.0 E(85289): 5.1e-15
Smith-Waterman score: 566; 34.9% identity (66.4% similar) in 298 aa overlap (38-311:33-326)
10 20 30 40 50 60
pF1KE9 AEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLA------AFGNLLVMIAILHFK
:.:.: :.. .:::.::. :: .:.
NP_000 QPGNGSAFLLAPNRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 QLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLF
.:.: ::..:.::::::...:..:.::.... . . : ::. .:.: : .:. ::.
NP_000 RLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIE
70 80 90 100 110 120
130 140 150 160 170
pF1KE9 HLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSI----FYTGANEEGI
:: :.::::.:.:.:. : . .: . . . :.. :. : :: .: ....:.:
NP_000 TLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE9 EELVVALTCVGGCQAPLNQNWVLLCFLL-FFIPNVAMVFIYSKIFLVAKHQARKIESTAS
. . :: :. :: ... .. :..: : :::.::..: ::.: .::... .
NP_000 N-CYANETC---CDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEG
190 200 210 220 230
240 250 260 270 280
pF1KE9 Q--AQSSSESYKE--------RVAK---RERKAAKTLGIAMAAFLVSWLPYLVDAVIDAY
. .:. :. .. : .: .:.:: ::::: :..: . :::... .. .
NP_000 RFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE9 MNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSE
.. . :: .: : : ::..:::::
NP_000 QDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNG
300 310 320 330 340 350
>>NP_001035262 (OMIM: 602164) 5-hydroxytryptamine recept (360 aa)
initn: 556 init1: 249 opt: 421 Z-score: 380.1 bits: 78.9 E(85289): 2e-14
Smith-Waterman score: 612; 34.2% identity (65.8% similar) in 310 aa overlap (32-326:19-327)
10 20 30 40 50 60
pF1KE9 VNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFK
. .: . :. ..: .::::::.:. .
NP_001 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDR
10 20 30 40
70 80 90 100 110 120
pF1KE9 QLHT-PTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL
::. ::..:.::: ::.::.: ::::.... :.. : .:. .: .: .:. . ::.
NP_001 QLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASI
50 60 70 80 90 100
130 140 150 160 170
pF1KE9 FHLCCISVDRYIAVT-DPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEE
:::::::.::: :. .::.: .:.: .. . : . . :: .. : :. :: .
NP_001 FHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIID
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE9 LVVAL-----TCVGGCQAPLNQNWVLLCFLL-FFIPNVAMVFIYSKIFLVAKHQARKIE-
:. . : .:. ... : .. :.:: . ::. : .:...::..:..:.
NP_001 LIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQM
170 180 190 200 210 220
240 250 260 270 280
pF1KE9 ------STASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNF
:. :. ::... .:. . : :::::: : :. : . : :..: ..: ....
NP_001 LQRAGASSESRPQSADQHSTHRM-RTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDY
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE9 ITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVE
.: :. ..: : ::..::..:::. . : .:. .:.
NP_001 TVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCS
290 300 310 320 330 340
pF1KE9 TD
NP_001 TTTINGSTHVLRF
350 360
>>NP_955525 (OMIM: 602164) 5-hydroxytryptamine receptor (378 aa)
initn: 556 init1: 249 opt: 421 Z-score: 380.0 bits: 78.9 E(85289): 2e-14
Smith-Waterman score: 612; 34.2% identity (65.8% similar) in 310 aa overlap (32-326:19-327)
10 20 30 40 50 60
pF1KE9 VNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFK
. .: . :. ..: .::::::.:. .
NP_955 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDR
10 20 30 40
70 80 90 100 110 120
pF1KE9 QLHT-PTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL
::. ::..:.::: ::.::.: ::::.... :.. : .:. .: .: .:. . ::.
NP_955 QLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASI
50 60 70 80 90 100
130 140 150 160 170
pF1KE9 FHLCCISVDRYIAVT-DPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEE
:::::::.::: :. .::.: .:.: .. . : . . :: .. : :. :: .
NP_955 FHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIID
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE9 LVVAL-----TCVGGCQAPLNQNWVLLCFLL-FFIPNVAMVFIYSKIFLVAKHQARKIE-
:. . : .:. ... : .. :.:: . ::. : .:...::..:..:.
NP_955 LIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQM
170 180 190 200 210 220
240 250 260 270 280
pF1KE9 ------STASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNF
:. :. ::... .:. . : :::::: : :. : . : :..: ..: ....
NP_955 LQRAGASSESRPQSADQHSTHRM-RTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDY
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE9 ITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVE
.: :. ..: : ::..::..:::. . : .:. .:.
NP_955 TVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCS
290 300 310 320 330 340
pF1KE9 TD
NP_955 TTTINGSTHVLSGCSPVSSFLLLFCNRPVPV
350 360 370
348 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:52:56 2016 done: Mon Nov 7 03:52:57 2016
Total Scan time: 5.980 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]