Result of FASTA (omim) for
pFN21AE9414
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9414, 361 aa
1>>>pF1KE9414 361 - 361 aa - 361 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5245+/-0.000474; mu= 20.9292+/- 0.030
mean_var=97.4188+/-26.994, 0's: 0 Z-trim(110.0): 464 B-trim: 2127 in 2/48
Lambda= 0.129943
statistics sampled from 17618 (18322) to 17618 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.57), E-opt: 0.2 (0.215), width: 16
Scan time: 7.290
The best scores are: opt bits E(85289)
NP_005675 (OMIM: 604106) probable G-protein couple ( 361) 2484 476.8 3.3e-134
NP_005285 (OMIM: 601909) probable G-protein couple ( 349) 1595 310.1 4.8e-84
XP_005251990 (OMIM: 601909) PREDICTED: probable G- ( 349) 1595 310.1 4.8e-84
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 375 81.4 3.4e-15
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362) 375 81.4 3.4e-15
NP_001124527 (OMIM: 142703) histamine H2 receptor ( 397) 375 81.5 3.6e-15
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422) 375 81.5 3.8e-15
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422) 375 81.5 3.8e-15
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422) 375 81.5 3.8e-15
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422) 375 81.5 3.8e-15
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422) 375 81.5 3.8e-15
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 308 69.0 2.4e-11
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 308 69.1 2.6e-11
NP_000668 (OMIM: 600445) adenosine receptor A3 iso ( 318) 298 66.9 7e-11
NP_612200 (OMIM: 609333) trace amine-associated re ( 339) 298 67.0 7.3e-11
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 289 65.3 2.4e-10
NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413) 284 64.4 5.1e-10
XP_011507677 (OMIM: 612250) PREDICTED: G-protein c ( 529) 284 64.6 5.9e-10
XP_016856350 (OMIM: 612250) PREDICTED: G-protein c ( 529) 284 64.6 5.9e-10
XP_005245114 (OMIM: 612250) PREDICTED: G-protein c ( 529) 284 64.6 5.9e-10
XP_011507678 (OMIM: 612250) PREDICTED: G-protein c ( 529) 284 64.6 5.9e-10
NP_001254539 (OMIM: 612250) G-protein coupled rece ( 529) 284 64.6 5.9e-10
NP_722561 (OMIM: 612250) G-protein coupled recepto ( 529) 284 64.6 5.9e-10
XP_005245113 (OMIM: 612250) PREDICTED: G-protein c ( 529) 284 64.6 5.9e-10
XP_016856351 (OMIM: 612250) PREDICTED: G-protein c ( 529) 284 64.6 5.9e-10
XP_011507680 (OMIM: 612250) PREDICTED: G-protein c ( 529) 284 64.6 5.9e-10
XP_016856349 (OMIM: 612250) PREDICTED: G-protein c ( 529) 284 64.6 5.9e-10
XP_011507679 (OMIM: 612250) PREDICTED: G-protein c ( 529) 284 64.6 5.9e-10
NP_001254540 (OMIM: 612250) G-protein coupled rece ( 546) 284 64.6 6e-10
XP_016856348 (OMIM: 612250) PREDICTED: G-protein c ( 549) 284 64.6 6e-10
XP_005245112 (OMIM: 612250) PREDICTED: G-protein c ( 549) 284 64.6 6e-10
NP_001254538 (OMIM: 612250) G-protein coupled rece ( 549) 284 64.6 6e-10
XP_011507673 (OMIM: 612250) PREDICTED: G-protein c ( 552) 284 64.6 6e-10
XP_011507674 (OMIM: 612250) PREDICTED: G-protein c ( 552) 284 64.6 6e-10
XP_006711314 (OMIM: 612250) PREDICTED: G-protein c ( 552) 284 64.6 6e-10
XP_016856347 (OMIM: 612250) PREDICTED: G-protein c ( 552) 284 64.6 6e-10
XP_011507672 (OMIM: 612250) PREDICTED: G-protein c ( 552) 284 64.6 6e-10
XP_011507675 (OMIM: 612250) PREDICTED: G-protein c ( 552) 284 64.6 6e-10
XP_006711316 (OMIM: 612250) PREDICTED: G-protein c ( 609) 284 64.7 6.4e-10
NP_055441 (OMIM: 604849) trace amine-associated re ( 306) 277 63.0 1.1e-09
NP_001028252 (OMIM: 604849) trace amine-associated ( 351) 277 63.0 1.1e-09
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic ( 408) 273 62.4 2.1e-09
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 273 62.5 2.3e-09
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 271 61.9 2.5e-09
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 268 61.5 4.2e-09
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 268 61.5 4.3e-09
NP_848566 (OMIM: 300513) glucose-dependent insulin ( 335) 266 60.9 4.6e-09
NP_062874 (OMIM: 182137) 5-hydroxytryptamine recep ( 432) 266 61.1 5.4e-09
NP_000863 (OMIM: 182137) 5-hydroxytryptamine recep ( 445) 266 61.1 5.5e-09
NP_062873 (OMIM: 182137) 5-hydroxytryptamine recep ( 479) 266 61.2 5.7e-09
>>NP_005675 (OMIM: 604106) probable G-protein coupled re (361 aa)
initn: 2484 init1: 2484 opt: 2484 Z-score: 2530.5 bits: 476.8 E(85289): 3.3e-134
Smith-Waterman score: 2484; 100.0% identity (100.0% similar) in 361 aa overlap (1-361:1-361)
10 20 30 40 50 60
pF1KE9 MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 VIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 ISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 GKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 RARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCS
310 320 330 340 350 360
pF1KE9 I
:
NP_005 I
>>NP_005285 (OMIM: 601909) probable G-protein coupled re (349 aa)
initn: 1591 init1: 1140 opt: 1595 Z-score: 1629.9 bits: 310.1 E(85289): 4.8e-84
Smith-Waterman score: 1595; 67.5% identity (85.8% similar) in 345 aa overlap (20-361:8-349)
10 20 30 40 50 60
pF1KE9 MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLT
: : . : :.::. .:. :..:...::.:: :::.::.
NP_005 MNSTLDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNII
10 20 30 40
70 80 90 100 110 120
pF1KE9 VIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYI
:::::::::::.:.::::::::::::::::::::.::.:::::. :.::::::.::..
NP_005 VIFVFHCAPLLNHHTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE9 ISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGW
.::::::::: :::::.:::.::::::.:: :::: :::.::.:::.:: :.:::::: :
NP_005 VSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHW
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE9 GKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDR
::::::::.:.::: :: :..::: ::: .::::::..::::::.::.::.::::.:..:
NP_005 GKPGYHGDVFQWCAESWHTDSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTKDISER
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 RARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSF
.::: :. ... :. ::.::::::::::::::.:::::::::::::: .: ::
NP_005 QARFSSQSGETG-EVQACPDKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHSNRFASF
230 240 250 260 270 280
310 320 330 340 350
pF1KE9 LTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEP---KPRKRAN
::::::::::::::::::::::::. ::.::: .::::: ... :..: . . :
NP_005 LTTWLAISNSFCNCVIYSLSNSVFQRGLKRLSGAMCTSC--ASQTTANDPYTVRSKGPLN
290 300 310 320 330 340
360
pF1KE9 SCSI
.: :
NP_005 GCHI
>>XP_005251990 (OMIM: 601909) PREDICTED: probable G-prot (349 aa)
initn: 1591 init1: 1140 opt: 1595 Z-score: 1629.9 bits: 310.1 E(85289): 4.8e-84
Smith-Waterman score: 1595; 67.5% identity (85.8% similar) in 345 aa overlap (20-361:8-349)
10 20 30 40 50 60
pF1KE9 MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLT
: : . : :.::. .:. :..:...::.:: :::.::.
XP_005 MNSTLDGNQSSHPFCLLAFGYLETVNFCLLEVLIIVFLTVLIISGNII
10 20 30 40
70 80 90 100 110 120
pF1KE9 VIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYI
:::::::::::.:.::::::::::::::::::::.::.:::::. :.::::::.::..
XP_005 VIFVFHCAPLLNHHTTSYFIQTMAYADLFVGVSCVVPSLSLLHHPLPVEESLTCQIFGFV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE9 ISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGW
.::::::::: :::::.:::.::::::.:: :::: :::.::.:::.:: :.:::::: :
XP_005 VSVLKSVSMASLACISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYSTLVFLPSFFHW
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE9 GKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDR
::::::::.:.::: :: :..::: ::: .::::::..::::::.::.::.::::.:..:
XP_005 GKPGYHGDVFQWCAESWHTDSYFTLFIVMMLYAPAALIVCFTYFNIFRICQQHTKDISER
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 RARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSF
.::: :. ... :. ::.::::::::::::::.:::::::::::::: .: ::
XP_005 QARFSSQSGETG-EVQACPDKRYAMVLFRITSVFYILWLPYIIYFLLESSTGHSNRFASF
230 240 250 260 270 280
310 320 330 340 350
pF1KE9 LTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEP---KPRKRAN
::::::::::::::::::::::::. ::.::: .::::: ... :..: . . :
XP_005 LTTWLAISNSFCNCVIYSLSNSVFQRGLKRLSGAMCTSC--ASQTTANDPYTVRSKGPLN
290 300 310 320 330 340
360
pF1KE9 SCSI
.: :
XP_005 GCHI
>>NP_071640 (OMIM: 142703) histamine H2 receptor isoform (359 aa)
initn: 350 init1: 164 opt: 375 Z-score: 393.8 bits: 81.4 E(85289): 3.4e-15
Smith-Waterman score: 375; 29.3% identity (58.5% similar) in 294 aa overlap (44-331:22-302)
20 30 40 50 60 70
pF1KE9 MSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHH
:::...: .. .:::..: .. :..
NP_071 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRN
10 20 30 40 50
80 90 100 110 120 130
pF1KE9 YTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTG-VHESLTCQVFGYIISVLKSVSMACL
:. :: ..: .::..:. : : .. . : .. :... . .: ..:. :
NP_071 LTNC-FIVSLAITDLLLGLLVL-PFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNL
60 70 80 90 100
140 150 160 170 180 190
pF1KE9 ACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYS-CLIFLPSFFGWGKPGYHGDIFE
::.::: :. :: : :::: :. : ..:::. : : :: .::.. . . .
NP_071 FMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNH
110 120 130 140 150 160
200 210 220 230 240
pF1KE9 WCATSWLTSAYFTGFI--VCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEV
. . :.. . .: : ...:.::..:::. :...:.:: .. : ..
NP_071 TTSKCKVQVNEVYGLVDGLVTFYLPL-LIMCITYYRIFKVARDQAKRIN----HISSWKA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 DSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLD--NPTLSFLTTWLAI
. :: :. : :. ..: . :.::. :. .. : : : .: .. ::.
NP_071 ATIRE--HKATVTLAAVM----GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGY
230 240 250 260 270
310 320 330 340 350 360
pF1KE9 SNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
.:: : ..:. : :: : ..:
NP_071 ANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEK
280 290 300 310 320 330
>>XP_006714928 (OMIM: 142703) PREDICTED: histamine H2 re (362 aa)
initn: 350 init1: 164 opt: 375 Z-score: 393.7 bits: 81.4 E(85289): 3.4e-15
Smith-Waterman score: 375; 29.3% identity (58.5% similar) in 294 aa overlap (44-331:22-302)
20 30 40 50 60 70
pF1KE9 MSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHH
:::...: .. .:::..: .. :..
XP_006 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRN
10 20 30 40 50
80 90 100 110 120 130
pF1KE9 YTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTG-VHESLTCQVFGYIISVLKSVSMACL
:. :: ..: .::..:. : : .. . : .. :... . .: ..:. :
XP_006 LTNC-FIVSLAITDLLLGLLVL-PFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNL
60 70 80 90 100
140 150 160 170 180 190
pF1KE9 ACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYS-CLIFLPSFFGWGKPGYHGDIFE
::.::: :. :: : :::: :. : ..:::. : : :: .::.. . . .
XP_006 FMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNH
110 120 130 140 150 160
200 210 220 230 240
pF1KE9 WCATSWLTSAYFTGFI--VCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEV
. . :.. . .: : ...:.::..:::. :...:.:: .. : ..
XP_006 TTSKCKVQVNEVYGLVDGLVTFYLPL-LIMCITYYRIFKVARDQAKRIN----HISSWKA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 DSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLD--NPTLSFLTTWLAI
. :: :. : :. ..: . :.::. :. .. : : : .: .. ::.
XP_006 ATIRE--HKATVTLAAVM----GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGY
230 240 250 260 270
310 320 330 340 350 360
pF1KE9 SNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
.:: : ..:. : :: : ..:
XP_006 ANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEK
280 290 300 310 320 330
>>NP_001124527 (OMIM: 142703) histamine H2 receptor isof (397 aa)
initn: 330 init1: 164 opt: 375 Z-score: 393.3 bits: 81.5 E(85289): 3.6e-15
Smith-Waterman score: 375; 29.3% identity (58.5% similar) in 294 aa overlap (44-331:22-302)
20 30 40 50 60 70
pF1KE9 MSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHH
:::...: .. .:::..: .. :..
NP_001 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRN
10 20 30 40 50
80 90 100 110 120 130
pF1KE9 YTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTG-VHESLTCQVFGYIISVLKSVSMACL
:. :: ..: .::..:. : : .. . : .. :... . .: ..:. :
NP_001 LTNC-FIVSLAITDLLLGLLVL-PFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNL
60 70 80 90 100
140 150 160 170 180 190
pF1KE9 ACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYS-CLIFLPSFFGWGKPGYHGDIFE
::.::: :. :: : :::: :. : ..:::. : : :: .::.. . . .
NP_001 FMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNH
110 120 130 140 150 160
200 210 220 230 240
pF1KE9 WCATSWLTSAYFTGFI--VCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEV
. . :.. . .: : ...:.::..:::. :...:.:: .. : ..
NP_001 TTSKCKVQVNEVYGLVDGLVTFYLPL-LIMCITYYRIFKVARDQAKRIN----HISSWKA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 DSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLD--NPTLSFLTTWLAI
. :: :. : :. ..: . :.::. :. .. : : : .: .. ::.
NP_001 ATIRE--HKATVTLAAVM----GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGY
230 240 250 260 270
310 320 330 340 350 360
pF1KE9 SNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
.:: : ..:. : :: : ..:
NP_001 ANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEK
280 290 300 310 320 330
>>XP_011532851 (OMIM: 142703) PREDICTED: histamine H2 re (422 aa)
initn: 352 init1: 164 opt: 375 Z-score: 393.0 bits: 81.5 E(85289): 3.8e-15
Smith-Waterman score: 375; 29.3% identity (58.5% similar) in 294 aa overlap (44-331:22-302)
20 30 40 50 60 70
pF1KE9 MSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHH
:::...: .. .:::..: .. :..
XP_011 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRN
10 20 30 40 50
80 90 100 110 120 130
pF1KE9 YTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTG-VHESLTCQVFGYIISVLKSVSMACL
:. :: ..: .::..:. : : .. . : .. :... . .: ..:. :
XP_011 LTNC-FIVSLAITDLLLGLLVL-PFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNL
60 70 80 90 100
140 150 160 170 180 190
pF1KE9 ACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYS-CLIFLPSFFGWGKPGYHGDIFE
::.::: :. :: : :::: :. : ..:::. : : :: .::.. . . .
XP_011 FMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNH
110 120 130 140 150 160
200 210 220 230 240
pF1KE9 WCATSWLTSAYFTGFI--VCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEV
. . :.. . .: : ...:.::..:::. :...:.:: .. : ..
XP_011 TTSKCKVQVNEVYGLVDGLVTFYLPL-LIMCITYYRIFKVARDQAKRIN----HISSWKA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 DSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLD--NPTLSFLTTWLAI
. :: :. : :. ..: . :.::. :. .. : : : .: .. ::.
XP_011 ATIRE--HKATVTLAAVM----GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGY
230 240 250 260 270
310 320 330 340 350 360
pF1KE9 SNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
.:: : ..:. : :: : ..:
XP_011 ANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEK
280 290 300 310 320 330
>>XP_011532850 (OMIM: 142703) PREDICTED: histamine H2 re (422 aa)
initn: 352 init1: 164 opt: 375 Z-score: 393.0 bits: 81.5 E(85289): 3.8e-15
Smith-Waterman score: 375; 29.3% identity (58.5% similar) in 294 aa overlap (44-331:22-302)
20 30 40 50 60 70
pF1KE9 MSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHH
:::...: .. .:::..: .. :..
XP_011 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRN
10 20 30 40 50
80 90 100 110 120 130
pF1KE9 YTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTG-VHESLTCQVFGYIISVLKSVSMACL
:. :: ..: .::..:. : : .. . : .. :... . .: ..:. :
XP_011 LTNC-FIVSLAITDLLLGLLVL-PFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNL
60 70 80 90 100
140 150 160 170 180 190
pF1KE9 ACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYS-CLIFLPSFFGWGKPGYHGDIFE
::.::: :. :: : :::: :. : ..:::. : : :: .::.. . . .
XP_011 FMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNH
110 120 130 140 150 160
200 210 220 230 240
pF1KE9 WCATSWLTSAYFTGFI--VCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEV
. . :.. . .: : ...:.::..:::. :...:.:: .. : ..
XP_011 TTSKCKVQVNEVYGLVDGLVTFYLPL-LIMCITYYRIFKVARDQAKRIN----HISSWKA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 DSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLD--NPTLSFLTTWLAI
. :: :. : :. ..: . :.::. :. .. : : : .: .. ::.
XP_011 ATIRE--HKATVTLAAVM----GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGY
230 240 250 260 270
310 320 330 340 350 360
pF1KE9 SNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
.:: : ..:. : :: : ..:
XP_011 ANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEK
280 290 300 310 320 330
>>XP_005265961 (OMIM: 142703) PREDICTED: histamine H2 re (422 aa)
initn: 352 init1: 164 opt: 375 Z-score: 393.0 bits: 81.5 E(85289): 3.8e-15
Smith-Waterman score: 375; 29.3% identity (58.5% similar) in 294 aa overlap (44-331:22-302)
20 30 40 50 60 70
pF1KE9 MSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHH
:::...: .. .:::..: .. :..
XP_005 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRN
10 20 30 40 50
80 90 100 110 120 130
pF1KE9 YTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTG-VHESLTCQVFGYIISVLKSVSMACL
:. :: ..: .::..:. : : .. . : .. :... . .: ..:. :
XP_005 LTNC-FIVSLAITDLLLGLLVL-PFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNL
60 70 80 90 100
140 150 160 170 180 190
pF1KE9 ACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYS-CLIFLPSFFGWGKPGYHGDIFE
::.::: :. :: : :::: :. : ..:::. : : :: .::.. . . .
XP_005 FMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNH
110 120 130 140 150 160
200 210 220 230 240
pF1KE9 WCATSWLTSAYFTGFI--VCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEV
. . :.. . .: : ...:.::..:::. :...:.:: .. : ..
XP_005 TTSKCKVQVNEVYGLVDGLVTFYLPL-LIMCITYYRIFKVARDQAKRIN----HISSWKA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 DSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLD--NPTLSFLTTWLAI
. :: :. : :. ..: . :.::. :. .. : : : .: .. ::.
XP_005 ATIRE--HKATVTLAAVM----GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGY
230 240 250 260 270
310 320 330 340 350 360
pF1KE9 SNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
.:: : ..:. : :: : ..:
XP_005 ANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEK
280 290 300 310 320 330
>>XP_016864915 (OMIM: 142703) PREDICTED: histamine H2 re (422 aa)
initn: 352 init1: 164 opt: 375 Z-score: 393.0 bits: 81.5 E(85289): 3.8e-15
Smith-Waterman score: 375; 29.3% identity (58.5% similar) in 294 aa overlap (44-331:22-302)
20 30 40 50 60 70
pF1KE9 MSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHH
:::...: .. .:::..: .. :..
XP_016 MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRN
10 20 30 40 50
80 90 100 110 120 130
pF1KE9 YTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTG-VHESLTCQVFGYIISVLKSVSMACL
:. :: ..: .::..:. : : .. . : .. :... . .: ..:. :
XP_016 LTNC-FIVSLAITDLLLGLLVL-PFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNL
60 70 80 90 100
140 150 160 170 180 190
pF1KE9 ACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYS-CLIFLPSFFGWGKPGYHGDIFE
::.::: :. :: : :::: :. : ..:::. : : :: .::.. . . .
XP_016 FMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNH
110 120 130 140 150 160
200 210 220 230 240
pF1KE9 WCATSWLTSAYFTGFI--VCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEV
. . :.. . .: : ...:.::..:::. :...:.:: .. : ..
XP_016 TTSKCKVQVNEVYGLVDGLVTFYLPL-LIMCITYYRIFKVARDQAKRIN----HISSWKA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 DSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLD--NPTLSFLTTWLAI
. :: :. : :. ..: . :.::. :. .. : : : .: .. ::.
XP_016 ATIRE--HKATVTLAAVM----GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGY
230 240 250 260 270
310 320 330 340 350 360
pF1KE9 SNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
.:: : ..:. : :: : ..:
XP_016 ANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEK
280 290 300 310 320 330
361 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:40:39 2016 done: Sun Nov 6 12:40:40 2016
Total Scan time: 7.290 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]