Result of FASTA (omim) for
pFN21AE9275
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9275, 268 aa
1>>>pF1KE9275 268 - 268 aa - 268 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.4470+/-0.000359; mu= -21.0374+/- 0.023
mean_var=409.0906+/-82.877, 0's: 0 Z-trim(126.1): 10 B-trim: 0 in 0/62
Lambda= 0.063411
statistics sampled from 51413 (51423) to 51413 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.845), E-opt: 0.2 (0.603), width: 16
Scan time: 7.490
The best scores are: opt bits E(85289)
NP_149074 (OMIM: 608315) ELL-associated factor 1 [ ( 268) 1816 178.9 8.7e-45
XP_011532467 (OMIM: 608315) PREDICTED: ELL-associa ( 167) 1069 110.4 2.2e-24
XP_011532468 (OMIM: 608315) PREDICTED: ELL-associa ( 167) 1069 110.4 2.2e-24
XP_005265575 (OMIM: 608315) PREDICTED: ELL-associa ( 167) 1069 110.4 2.2e-24
NP_060926 (OMIM: 607659) ELL-associated factor 2 i ( 260) 667 73.8 3.7e-13
XP_016862352 (OMIM: 607659) PREDICTED: ELL-associa ( 263) 667 73.8 3.8e-13
XP_005247675 (OMIM: 607659) PREDICTED: ELL-associa ( 271) 532 61.4 2e-09
NP_001306970 (OMIM: 607659) ELL-associated factor ( 130) 292 39.3 0.0044
XP_016862351 (OMIM: 607659) PREDICTED: ELL-associa ( 130) 292 39.3 0.0044
XP_016862350 (OMIM: 607659) PREDICTED: ELL-associa ( 130) 292 39.3 0.0044
>>NP_149074 (OMIM: 608315) ELL-associated factor 1 [Homo (268 aa)
initn: 1816 init1: 1816 opt: 1816 Z-score: 925.0 bits: 178.9 E(85289): 8.7e-45
Smith-Waterman score: 1816; 99.3% identity (100.0% similar) in 268 aa overlap (1-268:1-268)
10 20 30 40 50 60
pF1KE9 MNGTANPLLDREEHCLRLGESFEKRPRASFHTIRYDFKPASIDTSCEGELQVGKGDEVTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 MNGTANPLLDREEHCLRLGESFEKRPRASFHTIRYDFKPASIDTSCEGELQVGKGDEVTI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 TLPHIPGSTPPMTVFKGNKRPYQKDCVLIINHDTGEFVLEKLSSSIQVKKTRAEGSSKIQ
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
NP_149 TLPHIPGSTPPMTVFKGNKRPYQKDCVLIINHDTGEYVLEKLSSSIQVKKTRAEGSSKIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 ARMEQQPTRPPQTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 ARMEQQPTRPPQTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 VDIIEQMSSSSGSSSSDSESSSGSDDDSSSSGGEDNGPASPPQPSHQQPYNSRPAVANGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 VDIIEQMSSSSGSSSSDSESSSGSDDDSSSSGGEDNGPASPPQPSHQQPYNSRPAVANGT
190 200 210 220 230 240
250 260
pF1KE9 SRPQGSNQLMNALRNDLQLSESGSDSDD
:::::::::::.::::::::::::::::
NP_149 SRPQGSNQLMNTLRNDLQLSESGSDSDD
250 260
>>XP_011532467 (OMIM: 608315) PREDICTED: ELL-associated (167 aa)
initn: 1063 init1: 1063 opt: 1069 Z-score: 558.8 bits: 110.4 E(85289): 2.2e-24
Smith-Waterman score: 1069; 93.4% identity (98.2% similar) in 167 aa overlap (102-268:1-167)
80 90 100 110 120 130
pF1KE9 MTVFKGNKRPYQKDCVLIINHDTGEFVLEKLSSSIQVKKTRAEGSSKIQARMEQQPTRPP
..:... . . :::::::::::::::::::
XP_011 MKSQLHCHISLAEGSSKIQARMEQQPTRPP
10 20 30
140 150 160 170 180 190
pF1KE9 QTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRAEVDIIEQMSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRAEVDIIEQMSSSS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE9 GSSSSDSESSSGSDDDSSSSGGEDNGPASPPQPSHQQPYNSRPAVANGTSRPQGSNQLMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSSSSDSESSSGSDDDSSSSGGEDNGPASPPQPSHQQPYNSRPAVANGTSRPQGSNQLMN
100 110 120 130 140 150
260
pF1KE9 ALRNDLQLSESGSDSDD
.::::::::::::::::
XP_011 TLRNDLQLSESGSDSDD
160
>>XP_011532468 (OMIM: 608315) PREDICTED: ELL-associated (167 aa)
initn: 1063 init1: 1063 opt: 1069 Z-score: 558.8 bits: 110.4 E(85289): 2.2e-24
Smith-Waterman score: 1069; 93.4% identity (98.2% similar) in 167 aa overlap (102-268:1-167)
80 90 100 110 120 130
pF1KE9 MTVFKGNKRPYQKDCVLIINHDTGEFVLEKLSSSIQVKKTRAEGSSKIQARMEQQPTRPP
..:... . . :::::::::::::::::::
XP_011 MKSQLHCHISLAEGSSKIQARMEQQPTRPP
10 20 30
140 150 160 170 180 190
pF1KE9 QTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRAEVDIIEQMSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRAEVDIIEQMSSSS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE9 GSSSSDSESSSGSDDDSSSSGGEDNGPASPPQPSHQQPYNSRPAVANGTSRPQGSNQLMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSSSSDSESSSGSDDDSSSSGGEDNGPASPPQPSHQQPYNSRPAVANGTSRPQGSNQLMN
100 110 120 130 140 150
260
pF1KE9 ALRNDLQLSESGSDSDD
.::::::::::::::::
XP_011 TLRNDLQLSESGSDSDD
160
>>XP_005265575 (OMIM: 608315) PREDICTED: ELL-associated (167 aa)
initn: 1063 init1: 1063 opt: 1069 Z-score: 558.8 bits: 110.4 E(85289): 2.2e-24
Smith-Waterman score: 1069; 93.4% identity (98.2% similar) in 167 aa overlap (102-268:1-167)
80 90 100 110 120 130
pF1KE9 MTVFKGNKRPYQKDCVLIINHDTGEFVLEKLSSSIQVKKTRAEGSSKIQARMEQQPTRPP
..:... . . :::::::::::::::::::
XP_005 MKSQLHCHISLAEGSSKIQARMEQQPTRPP
10 20 30
140 150 160 170 180 190
pF1KE9 QTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRAEVDIIEQMSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRAEVDIIEQMSSSS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE9 GSSSSDSESSSGSDDDSSSSGGEDNGPASPPQPSHQQPYNSRPAVANGTSRPQGSNQLMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSSSSDSESSSGSDDDSSSSGGEDNGPASPPQPSHQQPYNSRPAVANGTSRPQGSNQLMN
100 110 120 130 140 150
260
pF1KE9 ALRNDLQLSESGSDSDD
.::::::::::::::::
XP_005 TLRNDLQLSESGSDSDD
160
>>NP_060926 (OMIM: 607659) ELL-associated factor 2 isofo (260 aa)
initn: 890 init1: 598 opt: 667 Z-score: 357.2 bits: 73.8 E(85289): 3.7e-13
Smith-Waterman score: 843; 54.5% identity (73.6% similar) in 277 aa overlap (1-268:1-260)
10 20 30 40 50
pF1KE9 MNGTAN-PLLDREEHCLRLGESFEKRPRASFHTIRYDFKPASIDTSCEGELQVGKGDEVT
::..:. :::.:. :.:::::::.:: .:::.:::::::::::: :: :.::.:..::
NP_060 MNSAAGFSHLDRRERVLKLGESFEKQPRCAFHTVRYDFKPASIDTSSEGYLEVGEGEQVT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 ITLPHIPGSTPPMTVFKGNKRPYQKDCVLIINHDTGEFVLEKLSSSIQVKKTRAEGSSKI
::::.: :::::.:::::.:.:: :.:.::::::::: ::::::.: :::::.::::::
NP_060 ITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKTRVEGSSKI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 QARMEQQPTRPPQTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRA
: : ::: . ... . : : :: .:. :: .:::.:::.:
NP_060 QYRKEQQQQQMWNSA---------------RTPNLVKHSPSEDKMSPASPIDDIERELKA
130 140 150 160
180 190 200 210 220 230
pF1KE9 EVDIIEQMSSSSGSSSSDSESSSGSDDDSSSSGGED-------NGPASPPQPSHQQPYNS
:.....:::: ..::.: : :::.:.:.::.: :: .: .:. : :
NP_060 EASLMDQMSSCDSSSDSKSSSSSSSEDSSSDSEDEDCKSSTSDTGNCVSGHPTMTQ-YRI
170 180 190 200 210 220
240 250 260
pF1KE9 RPAVANGTSRPQ-GSNQLMNALRNDLQLSESGSDSDD
: . . .: . .:. :::.::::::::::::::::
NP_060 -PDIDASHNRFRDNSGLLMNTLRNDLQLSESGSDSDD
230 240 250 260
>>XP_016862352 (OMIM: 607659) PREDICTED: ELL-associated (263 aa)
initn: 890 init1: 598 opt: 667 Z-score: 357.1 bits: 73.8 E(85289): 3.8e-13
Smith-Waterman score: 752; 51.9% identity (72.0% similar) in 264 aa overlap (1-255:1-247)
10 20 30 40 50
pF1KE9 MNGTAN-PLLDREEHCLRLGESFEKRPRASFHTIRYDFKPASIDTSCEGELQVGKGDEVT
::..:. :::.:. :.:::::::.:: .:::.:::::::::::: :: :.::.:..::
XP_016 MNSAAGFSHLDRRERVLKLGESFEKQPRCAFHTVRYDFKPASIDTSSEGYLEVGEGEQVT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 ITLPHIPGSTPPMTVFKGNKRPYQKDCVLIINHDTGEFVLEKLSSSIQVKKTRAEGSSKI
::::.: :::::.:::::.:.:: :.:.::::::::: ::::::.: :::::.::::::
XP_016 ITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKTRVEGSSKI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 QARMEQQPTRPPQTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRA
: : ::: . ... . : : :: .:. :: .:::.:::.:
XP_016 QYRKEQQQQQMWNSA---------------RTPNLVKHSPSEDKMSPASPIDDIERELKA
130 140 150 160
180 190 200 210 220 230
pF1KE9 EVDIIEQMSSSSGSSSSDSESSSGSDDDSSSSGGED-------NGPASPPQPSHQQPYNS
:.....:::: ..::.: : :::.:.:.::.: :: .: .:. : :
XP_016 EASLMDQMSSCDSSSDSKSSSSSSSEDSSSDSEDEDCKSSTSDTGNCVSGHPTMTQ-YRI
170 180 190 200 210 220
240 250 260
pF1KE9 RPAVANGTSRPQ-GSNQLMNALRNDLQLSESGSDSDD
: . . .: . .:. :::.: :
XP_016 -PDIDASHNRFRDNSGLLMNTLNNLSSHSFSSLYDPLLSH
230 240 250 260
>>XP_005247675 (OMIM: 607659) PREDICTED: ELL-associated (271 aa)
initn: 758 init1: 466 opt: 532 Z-score: 290.1 bits: 61.4 E(85289): 2e-09
Smith-Waterman score: 708; 52.6% identity (71.3% similar) in 247 aa overlap (30-268:42-271)
10 20 30 40 50
pF1KE9 MNGTANPLLDREEHCLRLGESFEKRPRASFHTIRYDFKPASIDTSCEGELQVGKGDEVT
: .. :::::::::: :: :.::.:..::
XP_005 LSSVPFSGSVICVFIWFFHAFFSNSIYSLLFSSFSDDFKPASIDTSSEGYLEVGEGEQVT
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE9 ITLPHIPGSTPPMTVFKGNKRPYQKDCVLIINHDTGEFVLEKLSSSIQVKKTRAEGSSKI
::::.: :::::.:::::.:.:: :.:.::::::::: ::::::.: :::::.::::::
XP_005 ITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKTRVEGSSKI
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE9 QARMEQQPTRPPQTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRA
: : ::: . ... . : : :: .:. :: .:::.:::.:
XP_005 QYRKEQQQQQMWNSA---------------RTPNLVKHSPSEDKMSPASPIDDIERELKA
140 150 160 170
180 190 200 210 220 230
pF1KE9 EVDIIEQMSSSSGSSSSDSESSSGSDDDSSSSGGED-------NGPASPPQPSHQQPYNS
:.....:::: ..::.: : :::.:.:.::.: :: .: .:. : :
XP_005 EASLMDQMSSCDSSSDSKSSSSSSSEDSSSDSEDEDCKSSTSDTGNCVSGHPTMTQ-YRI
180 190 200 210 220 230
240 250 260
pF1KE9 RPAVANGTSRPQ-GSNQLMNALRNDLQLSESGSDSDD
: . . .: . .:. :::.::::::::::::::::
XP_005 -PDIDASHNRFRDNSGLLMNTLRNDLQLSESGSDSDD
240 250 260 270
>>NP_001306970 (OMIM: 607659) ELL-associated factor 2 is (130 aa)
initn: 306 init1: 192 opt: 292 Z-score: 176.4 bits: 39.3 E(85289): 0.0044
Smith-Waterman score: 292; 46.5% identity (68.5% similar) in 127 aa overlap (150-268:6-130)
120 130 140 150 160 170
pF1KE9 QARMEQQPTRPPQTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRA
. : : :: .:. :: .:::.:::.:
NP_001 MWNSARTPNLVKHSPSEDKMSPASPIDDIERELKA
10 20 30
180 190 200 210 220 230
pF1KE9 EVDIIEQMSSSSGSSSSDSESSSGSDDDSSSSGGED-------NGPASPPQPSHQQPYNS
:.....:::: ..::.: : :::.:.:.::.: :: .: .:. : :
NP_001 EASLMDQMSSCDSSSDSKSSSSSSSEDSSSDSEDEDCKSSTSDTGNCVSGHPTMTQ-YRI
40 50 60 70 80 90
240 250 260
pF1KE9 RPAVANGTSRPQ-GSNQLMNALRNDLQLSESGSDSDD
: . . .: . .:. :::.::::::::::::::::
NP_001 -PDIDASHNRFRDNSGLLMNTLRNDLQLSESGSDSDD
100 110 120 130
>>XP_016862351 (OMIM: 607659) PREDICTED: ELL-associated (130 aa)
initn: 306 init1: 192 opt: 292 Z-score: 176.4 bits: 39.3 E(85289): 0.0044
Smith-Waterman score: 292; 46.5% identity (68.5% similar) in 127 aa overlap (150-268:6-130)
120 130 140 150 160 170
pF1KE9 QARMEQQPTRPPQTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRA
. : : :: .:. :: .:::.:::.:
XP_016 MWNSARTPNLVKHSPSEDKMSPASPIDDIERELKA
10 20 30
180 190 200 210 220 230
pF1KE9 EVDIIEQMSSSSGSSSSDSESSSGSDDDSSSSGGED-------NGPASPPQPSHQQPYNS
:.....:::: ..::.: : :::.:.:.::.: :: .: .:. : :
XP_016 EASLMDQMSSCDSSSDSKSSSSSSSEDSSSDSEDEDCKSSTSDTGNCVSGHPTMTQ-YRI
40 50 60 70 80 90
240 250 260
pF1KE9 RPAVANGTSRPQ-GSNQLMNALRNDLQLSESGSDSDD
: . . .: . .:. :::.::::::::::::::::
XP_016 -PDIDASHNRFRDNSGLLMNTLRNDLQLSESGSDSDD
100 110 120 130
>>XP_016862350 (OMIM: 607659) PREDICTED: ELL-associated (130 aa)
initn: 306 init1: 192 opt: 292 Z-score: 176.4 bits: 39.3 E(85289): 0.0044
Smith-Waterman score: 292; 46.5% identity (68.5% similar) in 127 aa overlap (150-268:6-130)
120 130 140 150 160 170
pF1KE9 QARMEQQPTRPPQTSQPPPPPPPMPFRAPTKPPVGPKTSPLKDNPSPEPQLDDIKRELRA
. : : :: .:. :: .:::.:::.:
XP_016 MWNSARTPNLVKHSPSEDKMSPASPIDDIERELKA
10 20 30
180 190 200 210 220 230
pF1KE9 EVDIIEQMSSSSGSSSSDSESSSGSDDDSSSSGGED-------NGPASPPQPSHQQPYNS
:.....:::: ..::.: : :::.:.:.::.: :: .: .:. : :
XP_016 EASLMDQMSSCDSSSDSKSSSSSSSEDSSSDSEDEDCKSSTSDTGNCVSGHPTMTQ-YRI
40 50 60 70 80 90
240 250 260
pF1KE9 RPAVANGTSRPQ-GSNQLMNALRNDLQLSESGSDSDD
: . . .: . .:. :::.::::::::::::::::
XP_016 -PDIDASHNRFRDNSGLLMNTLRNDLQLSESGSDSDD
100 110 120 130
268 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 10:23:04 2016 done: Tue Nov 8 10:23:06 2016
Total Scan time: 7.490 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]