FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE9256, 718 aa
  1>>>pF1KE9256 718 - 718 aa - 718 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 14.3552+/-0.00164; mu= -22.3273+/- 0.096
 mean_var=529.0015+/-114.669, 0's: 0 Z-trim(108.4): 158  B-trim: 0 in 0/52
 Lambda= 0.055763
 statistics sampled from 10052 (10169) to 10052 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.312), width:  16
 Scan time:  2.700

The best scores are:                                      opt bits E(32554)
CCDS43539.1 MAD1L1 gene_id:8379|Hs108|chr7         ( 718) 4488 376.7 6.5e-104
CCDS78201.1 MAD1L1 gene_id:8379|Hs108|chr7         ( 626) 3506 297.7 3.5e-80


>>CCDS43539.1 MAD1L1 gene_id:8379|Hs108|chr7              (718 aa)
 initn: 4488 init1: 4488 opt: 4488  Z-score: 1979.0  bits: 376.7 E(32554): 6.5e-104
Smith-Waterman score: 4488; 99.9% identity (100.0% similar) in 718 aa overlap (1-718:1-718)

               10        20        30        40        50        60
pF1KE9 MEDLGENTMVLSTLRSLNNFISQRVEGGSGLDISTSAPGSLQMQYQQSMQLEERAEQIRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MEDLGENTMVLSTLRSLNNFISQRVEGGSGLDISTSAPGSLQMQYQQSMQLEERAEQIRS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 KSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQLQEREAGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQLQEREAGA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 EEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQAGETINALKGRISELQWSVMDQEMRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 EEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQAGETINALKGRISELQWSVMDQEMRV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 KRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQEQDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQEQDAA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE9 IVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 IVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE9 VGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 VGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSAR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE9 GLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 GLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE9 ELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 ELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKML
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE9 KSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE9 KVLHMSLNPTSVARQRLHEDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKE
       :::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
CCDS43 KVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE9 VAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 VAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPG
              610       620       630       640       650       660

              670       680       690       700       710        
pF1KE9 DCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 DCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA
              670       680       690       700       710        

>>CCDS78201.1 MAD1L1 gene_id:8379|Hs108|chr7              (626 aa)
 initn: 3506 init1: 3506 opt: 3506  Z-score: 1552.9  bits: 297.7 E(32554): 3.5e-80
Smith-Waterman score: 3506; 99.8% identity (100.0% similar) in 561 aa overlap (158-718:66-626)

       130       140       150       160       170       180       
pF1KE9 LERNRQCQQNLDAASKRLREKEDSLAQAGETINALKGRISELQWSVMDQEMRVKRLESEK
                                     ::::::::::::::::::::::::::::::
CCDS78 PCQLSGVPYNTGDPVGRWARPCIWPCPWHTTINALKGRISELQWSVMDQEMRVKRLESEK
          40        50        60        70        80        90     

       190       200       210       220       230       240       
pF1KE9 QELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQEQDAAIVKNMKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 QELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQEQDAAIVKNMKS
         100       110       120       130       140       150     

       250       260       270       280       290       300       
pF1KE9 ELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETLVGLELEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 ELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETLVGLELEN
         160       170       180       190       200       210     

       310       320       330       340       350       360       
pF1KE9 ERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSARGLEKARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 ERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSARGLEKARQ
         220       230       240       250       260       270     

       370       380       390       400       410       420       
pF1KE9 QLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 QLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEY
         280       290       300       310       320       330     

       430       440       450       460       470       480       
pF1KE9 SPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 SPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSA
         340       350       360       370       380       390     

       490       500       510       520       530       540       
pF1KE9 EQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTKVLHMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 EQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTKVLHMSL
         400       410       420       430       440       450     

       550       560       570       580       590       600       
pF1KE9 NPTSVARQRLHEDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQ
       ::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 NPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQ
         460       470       480       490       500       510     

       610       620       630       640       650       660       
pF1KE9 VESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 VESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKA
         520       530       540       550       560       570     

       670       680       690       700       710        
pF1KE9 TSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA
       :::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 TSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA
         580       590       600       610       620      




718 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 17:00:51 2016 done: Mon Nov  7 17:00:52 2016
 Total Scan time:  2.700 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]