Result of FASTA (omim) for
pFN21AE9250
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9250, 353 aa
1>>>pF1KE9250 353 - 353 aa - 353 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0126+/-0.000479; mu= 12.4185+/- 0.029
mean_var=70.4194+/-14.687, 0's: 0 Z-trim(109.7): 16 B-trim: 1006 in 2/48
Lambda= 0.152837
statistics sampled from 17941 (17948) to 17941 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.592), E-opt: 0.2 (0.21), width: 16
Scan time: 6.150
The best scores are: opt bits E(85289)
NP_001094095 (OMIM: 611509) centromere protein N i ( 353) 2320 521.0 1.5e-147
XP_006721299 (OMIM: 611509) PREDICTED: centromere ( 339) 2025 456.0 5.5e-128
NP_001094094 (OMIM: 611509) centromere protein N i ( 339) 2025 456.0 5.5e-128
NP_001257402 (OMIM: 611509) centromere protein N i ( 319) 1417 321.9 1.2e-87
NP_001257403 (OMIM: 611509) centromere protein N i ( 305) 1174 268.3 1.5e-71
XP_016878945 (OMIM: 611509) PREDICTED: centromere ( 204) 1171 267.6 1.7e-71
NP_060925 (OMIM: 611509) centromere protein N isof ( 204) 1171 267.6 1.7e-71
>>NP_001094095 (OMIM: 611509) centromere protein N isofo (353 aa)
initn: 2320 init1: 2320 opt: 2320 Z-score: 2770.0 bits: 521.0 E(85289): 1.5e-147
Smith-Waterman score: 2320; 99.4% identity (100.0% similar) in 353 aa overlap (1-353:1-353)
10 20 30 40 50 60
pF1KE9 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ASISDAALLDIIYMQFHQHQKVWDVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVT
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 ASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 IASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 NIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSGLNGSILAERKEPLRCLIKFSSP
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 NIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSGLNGSILAEREEPLRCLIKFSSP
250 260 270 280 290 300
310 320 330 340 350
pF1KE9 HLLEALKSLAPAALVCRIQKLLCYSGSHSQGTQDPSSWQKDLYLLFVPLYPRC
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLLEALKSLAPAALVCRIQKLLCYSGSHSQGTQDPSSWQKDLYLLFVPLYPRC
310 320 330 340 350
>>XP_006721299 (OMIM: 611509) PREDICTED: centromere prot (339 aa)
initn: 2076 init1: 2025 opt: 2025 Z-score: 2418.7 bits: 456.0 E(85289): 5.5e-128
Smith-Waterman score: 2025; 98.7% identity (100.0% similar) in 314 aa overlap (1-314:1-314)
10 20 30 40 50 60
pF1KE9 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ASISDAALLDIIYMQFHQHQKVWDVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVT
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_006 ASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 IASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 NIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSGLNGSILAERKEPLRCLIKFSSP
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_006 NIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSGLNGSILAEREEPLRCLIKFSSP
250 260 270 280 290 300
310 320 330 340 350
pF1KE9 HLLEALKSLAPAALVCRIQKLLCYSGSHSQGTQDPSSWQKDLYLLFVPLYPRC
::::::::::::..
XP_006 HLLEALKSLAPAGIADAPLSPLLTCIPNKRMNYFKIRDK
310 320 330
>>NP_001094094 (OMIM: 611509) centromere protein N isofo (339 aa)
initn: 2076 init1: 2025 opt: 2025 Z-score: 2418.7 bits: 456.0 E(85289): 5.5e-128
Smith-Waterman score: 2025; 98.7% identity (100.0% similar) in 314 aa overlap (1-314:1-314)
10 20 30 40 50 60
pF1KE9 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ASISDAALLDIIYMQFHQHQKVWDVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVT
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 ASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 IASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 NIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSGLNGSILAERKEPLRCLIKFSSP
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 NIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSGLNGSILAEREEPLRCLIKFSSP
250 260 270 280 290 300
310 320 330 340 350
pF1KE9 HLLEALKSLAPAALVCRIQKLLCYSGSHSQGTQDPSSWQKDLYLLFVPLYPRC
::::::::::::..
NP_001 HLLEALKSLAPAGIADAPLSPLLTCIPNKRMNYFKIRDK
310 320 330
>>NP_001257402 (OMIM: 611509) centromere protein N isofo (319 aa)
initn: 1880 init1: 1417 opt: 1417 Z-score: 1694.6 bits: 321.9 E(85289): 1.2e-87
Smith-Waterman score: 1816; 92.4% identity (93.3% similar) in 314 aa overlap (1-314:1-294)
10 20 30 40 50 60
pF1KE9 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ASISDAALLDIIYMQFHQHQKVWDVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVT
:::::::::::: :::::::::::::::::::::::::::
NP_001 ASISDAALLDIIC--------------------EDVDLFDMKQFKNSFKKILQRALKNVT
70 80 90 100
130 140 150 160 170 180
pF1KE9 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALT
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE9 IASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE9 NIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSGLNGSILAERKEPLRCLIKFSSP
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 NIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSGLNGSILAEREEPLRCLIKFSSP
230 240 250 260 270 280
310 320 330 340 350
pF1KE9 HLLEALKSLAPAALVCRIQKLLCYSGSHSQGTQDPSSWQKDLYLLFVPLYPRC
::::::::::::..
NP_001 HLLEALKSLAPAGIADAPLSPLLTCIPNKRMNYFKIRDK
290 300 310
>>NP_001257403 (OMIM: 611509) centromere protein N isofo (305 aa)
initn: 1832 init1: 1164 opt: 1174 Z-score: 1405.4 bits: 268.3 E(85289): 1.5e-71
Smith-Waterman score: 1734; 87.9% identity (89.2% similar) in 314 aa overlap (1-314:1-280)
10 20 30 40 50 60
pF1KE9 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ASISDAALLDIIYMQFHQHQKVWDVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVT
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 ASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQ---
130 140 150 160 170
190 200 210 220 230 240
pF1KE9 IASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHE
:::::::::::::::::::::::::::::
NP_001 -------------------------------TFETHNSTTPLQERSLGLDINMDSRIIHE
180 190 200
250 260 270 280 290 300
pF1KE9 NIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSGLNGSILAERKEPLRCLIKFSSP
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 NIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSGLNGSILAEREEPLRCLIKFSSP
210 220 230 240 250 260
310 320 330 340 350
pF1KE9 HLLEALKSLAPAALVCRIQKLLCYSGSHSQGTQDPSSWQKDLYLLFVPLYPRC
::::::::::::..
NP_001 HLLEALKSLAPAGIADAPLSPLLTCIPNKRMNYFKIRDK
270 280 290 300
>>XP_016878945 (OMIM: 611509) PREDICTED: centromere prot (204 aa)
initn: 1197 init1: 1171 opt: 1171 Z-score: 1404.7 bits: 267.6 E(85289): 1.7e-71
Smith-Waterman score: 1171; 96.7% identity (98.4% similar) in 184 aa overlap (1-184:1-184)
10 20 30 40 50 60
pF1KE9 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ASISDAALLDIIYMQFHQHQKVWDVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVT
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_016 ASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQELE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 IASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHE
..:
XP_016 ATGKIYLRQEEIILDITEMKKACN
190 200
>>NP_060925 (OMIM: 611509) centromere protein N isoform (204 aa)
initn: 1197 init1: 1171 opt: 1171 Z-score: 1404.7 bits: 267.6 E(85289): 1.7e-71
Smith-Waterman score: 1171; 96.7% identity (98.4% similar) in 184 aa overlap (1-184:1-184)
10 20 30 40 50 60
pF1KE9 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ASISDAALLDIIYMQFHQHQKVWDVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVT
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_060 ASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_060 VSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQELE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 IASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHE
..:
NP_060 ATGKIYLRQEEIILDITEMKKACN
190 200
353 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 06:30:28 2016 done: Sun Nov 6 06:30:29 2016
Total Scan time: 6.150 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]