Result of FASTA (omim) for
pFN21AE6789
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6789, 580 aa
1>>>pF1KE6789 580 - 580 aa - 580 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2817+/-0.000421; mu= 18.6297+/- 0.026
mean_var=64.4997+/-12.979, 0's: 0 Z-trim(110.4): 46 B-trim: 48 in 2/51
Lambda= 0.159697
statistics sampled from 18672 (18691) to 18672 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.219), width: 16
Scan time: 8.910
The best scores are: opt bits E(85289)
XP_005265572 (OMIM: 614828,614830) PREDICTED: prot ( 580) 3930 914.8 0
XP_011532465 (OMIM: 614828,614830) PREDICTED: prot ( 580) 3930 914.8 0
XP_016862842 (OMIM: 614828,614830) PREDICTED: prot ( 580) 3930 914.8 0
XP_011532466 (OMIM: 614828,614830) PREDICTED: prot ( 580) 3930 914.8 0
NP_116195 (OMIM: 614828,614830) protein O-linked-m ( 580) 3930 914.8 0
XP_016861695 (OMIM: 614789,615297) PREDICTED: EGF ( 527) 259 69.0 4.4e-11
XP_005264800 (OMIM: 614789,615297) PREDICTED: EGF ( 527) 259 69.0 4.4e-11
NP_001265618 (OMIM: 614789,615297) EGF domain-spec ( 527) 259 69.0 4.4e-11
XP_016861694 (OMIM: 614789,615297) PREDICTED: EGF ( 527) 259 69.0 4.4e-11
XP_016861698 (OMIM: 614789,615297) PREDICTED: EGF ( 252) 253 67.4 6.2e-11
XP_016861696 (OMIM: 614789,615297) PREDICTED: EGF ( 300) 253 67.5 7.2e-11
XP_011531905 (OMIM: 614789,615297) PREDICTED: EGF ( 544) 253 67.6 1.2e-10
XP_016861693 (OMIM: 614789,615297) PREDICTED: EGF ( 544) 253 67.6 1.2e-10
XP_011531904 (OMIM: 614789,615297) PREDICTED: EGF ( 545) 253 67.6 1.2e-10
XP_011531901 (OMIM: 614789,615297) PREDICTED: EGF ( 545) 253 67.6 1.2e-10
XP_011531902 (OMIM: 614789,615297) PREDICTED: EGF ( 545) 253 67.6 1.2e-10
NP_775925 (OMIM: 614789,615297) EGF domain-specifi ( 443) 202 55.8 3.4e-07
>>XP_005265572 (OMIM: 614828,614830) PREDICTED: protein (580 aa)
initn: 3930 init1: 3930 opt: 3930 Z-score: 4890.2 bits: 914.8 E(85289): 0
Smith-Waterman score: 3930; 100.0% identity (100.0% similar) in 580 aa overlap (1-580:1-580)
10 20 30 40 50 60
pF1KE6 MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALSRQATEPAPALRIDYPKALQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALSRQATEPAPALRIDYPKALQIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNTSVMLPNLGSRRFQPALLDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNTSVMLPNLGSRRFQPALLDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TVEDHNTQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVEDHNTQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 QFPGLAHEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFPGLAHEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKIT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 TWYQYGFVQPQGPKANILVSGNEIRQFARFMTEKLNVSHTGVPLGEEYILVFSRTQNRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TWYQYGFVQPQGPKANILVSGNEIRQFARFMTEKLNVSHTGVPLGEEYILVFSRTQNRLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 LNEAELLLALAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNEAELLLALAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWRNMMPENTVTHPERPWDQGGITHLDRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWRNMMPENTVTHPERPWDQGGITHLDRA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 EQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQKWTVGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQKWTVGL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 YPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILA
490 500 510 520 530 540
550 560 570 580
pF1KE6 LQNHTFTENIKPFTTYLVWVRCIFNKILLGPFADVLVCNT
::::::::::::::::::::::::::::::::::::::::
XP_005 LQNHTFTENIKPFTTYLVWVRCIFNKILLGPFADVLVCNT
550 560 570 580
>>XP_011532465 (OMIM: 614828,614830) PREDICTED: protein (580 aa)
initn: 3930 init1: 3930 opt: 3930 Z-score: 4890.2 bits: 914.8 E(85289): 0
Smith-Waterman score: 3930; 100.0% identity (100.0% similar) in 580 aa overlap (1-580:1-580)
10 20 30 40 50 60
pF1KE6 MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALSRQATEPAPALRIDYPKALQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALSRQATEPAPALRIDYPKALQIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNTSVMLPNLGSRRFQPALLDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNTSVMLPNLGSRRFQPALLDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TVEDHNTQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVEDHNTQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 QFPGLAHEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFPGLAHEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKIT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 TWYQYGFVQPQGPKANILVSGNEIRQFARFMTEKLNVSHTGVPLGEEYILVFSRTQNRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TWYQYGFVQPQGPKANILVSGNEIRQFARFMTEKLNVSHTGVPLGEEYILVFSRTQNRLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 LNEAELLLALAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNEAELLLALAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWRNMMPENTVTHPERPWDQGGITHLDRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWRNMMPENTVTHPERPWDQGGITHLDRA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 EQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQKWTVGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQKWTVGL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 YPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILA
490 500 510 520 530 540
550 560 570 580
pF1KE6 LQNHTFTENIKPFTTYLVWVRCIFNKILLGPFADVLVCNT
::::::::::::::::::::::::::::::::::::::::
XP_011 LQNHTFTENIKPFTTYLVWVRCIFNKILLGPFADVLVCNT
550 560 570 580
>>XP_016862842 (OMIM: 614828,614830) PREDICTED: protein (580 aa)
initn: 3930 init1: 3930 opt: 3930 Z-score: 4890.2 bits: 914.8 E(85289): 0
Smith-Waterman score: 3930; 100.0% identity (100.0% similar) in 580 aa overlap (1-580:1-580)
10 20 30 40 50 60
pF1KE6 MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALSRQATEPAPALRIDYPKALQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALSRQATEPAPALRIDYPKALQIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNTSVMLPNLGSRRFQPALLDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNTSVMLPNLGSRRFQPALLDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TVEDHNTQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVEDHNTQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 QFPGLAHEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFPGLAHEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKIT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 TWYQYGFVQPQGPKANILVSGNEIRQFARFMTEKLNVSHTGVPLGEEYILVFSRTQNRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TWYQYGFVQPQGPKANILVSGNEIRQFARFMTEKLNVSHTGVPLGEEYILVFSRTQNRLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 LNEAELLLALAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNEAELLLALAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWRNMMPENTVTHPERPWDQGGITHLDRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWRNMMPENTVTHPERPWDQGGITHLDRA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 EQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQKWTVGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQKWTVGL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 YPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILA
490 500 510 520 530 540
550 560 570 580
pF1KE6 LQNHTFTENIKPFTTYLVWVRCIFNKILLGPFADVLVCNT
::::::::::::::::::::::::::::::::::::::::
XP_016 LQNHTFTENIKPFTTYLVWVRCIFNKILLGPFADVLVCNT
550 560 570 580
>>XP_011532466 (OMIM: 614828,614830) PREDICTED: protein (580 aa)
initn: 3930 init1: 3930 opt: 3930 Z-score: 4890.2 bits: 914.8 E(85289): 0
Smith-Waterman score: 3930; 100.0% identity (100.0% similar) in 580 aa overlap (1-580:1-580)
10 20 30 40 50 60
pF1KE6 MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALSRQATEPAPALRIDYPKALQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALSRQATEPAPALRIDYPKALQIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNTSVMLPNLGSRRFQPALLDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNTSVMLPNLGSRRFQPALLDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TVEDHNTQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVEDHNTQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 QFPGLAHEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFPGLAHEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKIT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 TWYQYGFVQPQGPKANILVSGNEIRQFARFMTEKLNVSHTGVPLGEEYILVFSRTQNRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TWYQYGFVQPQGPKANILVSGNEIRQFARFMTEKLNVSHTGVPLGEEYILVFSRTQNRLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 LNEAELLLALAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNEAELLLALAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWRNMMPENTVTHPERPWDQGGITHLDRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWRNMMPENTVTHPERPWDQGGITHLDRA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 EQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQKWTVGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQKWTVGL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 YPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILA
490 500 510 520 530 540
550 560 570 580
pF1KE6 LQNHTFTENIKPFTTYLVWVRCIFNKILLGPFADVLVCNT
::::::::::::::::::::::::::::::::::::::::
XP_011 LQNHTFTENIKPFTTYLVWVRCIFNKILLGPFADVLVCNT
550 560 570 580
>>NP_116195 (OMIM: 614828,614830) protein O-linked-manno (580 aa)
initn: 3930 init1: 3930 opt: 3930 Z-score: 4890.2 bits: 914.8 E(85289): 0
Smith-Waterman score: 3930; 100.0% identity (100.0% similar) in 580 aa overlap (1-580:1-580)
10 20 30 40 50 60
pF1KE6 MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALSRQATEPAPALRIDYPKALQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MHLSAVFNALLVSVLAAVLWKHVRLREHAATLEEELALSRQATEPAPALRIDYPKALQIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNTSVMLPNLGSRRFQPALLDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MEGGTHMVCTGRTHTDRICRFKWLCYSNEAEEFIFFHGNTSVMLPNLGSRRFQPALLDLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TVEDHNTQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 TVEDHNTQYFNFVELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 QFPGLAHEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 QFPGLAHEARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTLGRLLCFSHAFVGLSKIT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 TWYQYGFVQPQGPKANILVSGNEIRQFARFMTEKLNVSHTGVPLGEEYILVFSRTQNRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 TWYQYGFVQPQGPKANILVSGNEIRQFARFMTEKLNVSHTGVPLGEEYILVFSRTQNRLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 LNEAELLLALAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LNEAELLLALAQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWRNMMPENTVTHPERPWDQGGITHLDRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 VVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWRNMMPENTVTHPERPWDQGGITHLDRA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 EQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQKWTVGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 EQARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQKWTVGL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 YPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 YPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTYVPYILA
490 500 510 520 530 540
550 560 570 580
pF1KE6 LQNHTFTENIKPFTTYLVWVRCIFNKILLGPFADVLVCNT
::::::::::::::::::::::::::::::::::::::::
NP_116 LQNHTFTENIKPFTTYLVWVRCIFNKILLGPFADVLVCNT
550 560 570 580
>>XP_016861695 (OMIM: 614789,615297) PREDICTED: EGF doma (527 aa)
initn: 133 init1: 77 opt: 259 Z-score: 319.9 bits: 69.0 E(85289): 4.4e-11
Smith-Waterman score: 259; 26.9% identity (57.7% similar) in 305 aa overlap (163-449:245-525)
140 150 160 170 180 190
pF1KE6 VELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAHEARLF
:..: : : .. :. : . ... .. .
XP_016 TQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCD-FINLYITQHVNNSFSTDVYIV
220 230 240 250 260 270
200 210 220 230 240
pF1KE6 FME--GWGEGAHF-DLYKLLSPKQPLLRAQLKTL-GRLLCFSHAFVGLSKITTWYQYGFV
. . ..: : : : .. .. . . .::: .. .::..: .: ..::.
XP_016 MWDTSSYGYGDLFSDTWNAFTDYDVI---HLKTYDSKRVCFKEAVFSL---LPRMRYGLF
280 290 300 310 320
250 260 270 280 290 300
pF1KE6 QPQGPKANILVSGNE----IRQFARFMTEKLNVSHTGVPLGEEYILVFSR-TQNRLILNE
. : :.:: . .: ::. . ..::... : :. . ...: :. : :::.
XP_016 Y-NTP----LISGCQNTGLFRAFAQHVLHRLNITQEGPKDGKIRVTILARSTEYRKILNQ
330 340 350 360 370 380
310 320 330 340 350 360
pF1KE6 AELLLAL--AQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGATV
::. :: .. :... : . .. : : .:.. :......:::: :. :::: :.:
XP_016 NELVNALKTVSTFEVQIVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAV
390 400 410 420 430 440
370 380 390 400 410
pF1KE6 VELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWR---NMMPENTVTHP---ERPWDQGGIT
::. : . : :: : :. .:..:: ...:.. :: :.: .
XP_016 FELY----NCEDERCYLDLARLRGV--HYITWRRQNKVFPQDKGHHPTLGEHP--KFTNY
450 460 470 480 490
420 430 440 450 460 470
pF1KE6 HLDRAE-QARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQ
.: : . .::. . :. ..:.: :. .:
XP_016 SFDVEEFMYLVLQAAD---HVL-QHPKWPFKKKHDEL
500 510 520
480 490 500 510 520 530
pF1KE6 KWTVGLYPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTY
>>XP_005264800 (OMIM: 614789,615297) PREDICTED: EGF doma (527 aa)
initn: 133 init1: 77 opt: 259 Z-score: 319.9 bits: 69.0 E(85289): 4.4e-11
Smith-Waterman score: 259; 26.9% identity (57.7% similar) in 305 aa overlap (163-449:245-525)
140 150 160 170 180 190
pF1KE6 VELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAHEARLF
:..: : : .. :. : . ... .. .
XP_005 TQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCD-FINLYITQHVNNSFSTDVYIV
220 230 240 250 260 270
200 210 220 230 240
pF1KE6 FME--GWGEGAHF-DLYKLLSPKQPLLRAQLKTL-GRLLCFSHAFVGLSKITTWYQYGFV
. . ..: : : : .. .. . . .::: .. .::..: .: ..::.
XP_005 MWDTSSYGYGDLFSDTWNAFTDYDVI---HLKTYDSKRVCFKEAVFSL---LPRMRYGLF
280 290 300 310 320
250 260 270 280 290 300
pF1KE6 QPQGPKANILVSGNE----IRQFARFMTEKLNVSHTGVPLGEEYILVFSR-TQNRLILNE
. : :.:: . .: ::. . ..::... : :. . ...: :. : :::.
XP_005 Y-NTP----LISGCQNTGLFRAFAQHVLHRLNITQEGPKDGKIRVTILARSTEYRKILNQ
330 340 350 360 370 380
310 320 330 340 350 360
pF1KE6 AELLLAL--AQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGATV
::. :: .. :... : . .. : : .:.. :......:::: :. :::: :.:
XP_005 NELVNALKTVSTFEVQIVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAV
390 400 410 420 430 440
370 380 390 400 410
pF1KE6 VELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWR---NMMPENTVTHP---ERPWDQGGIT
::. : . : :: : :. .:..:: ...:.. :: :.: .
XP_005 FELY----NCEDERCYLDLARLRGV--HYITWRRQNKVFPQDKGHHPTLGEHP--KFTNY
450 460 470 480 490
420 430 440 450 460 470
pF1KE6 HLDRAE-QARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQ
.: : . .::. . :. ..:.: :. .:
XP_005 SFDVEEFMYLVLQAAD---HVL-QHPKWPFKKKHDEL
500 510 520
480 490 500 510 520 530
pF1KE6 KWTVGLYPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTY
>>NP_001265618 (OMIM: 614789,615297) EGF domain-specific (527 aa)
initn: 133 init1: 77 opt: 259 Z-score: 319.9 bits: 69.0 E(85289): 4.4e-11
Smith-Waterman score: 259; 26.9% identity (57.7% similar) in 305 aa overlap (163-449:245-525)
140 150 160 170 180 190
pF1KE6 VELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAHEARLF
:..: : : .. :. : . ... .. .
NP_001 TQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCD-FINLYITQHVNNSFSTDVYIV
220 230 240 250 260 270
200 210 220 230 240
pF1KE6 FME--GWGEGAHF-DLYKLLSPKQPLLRAQLKTL-GRLLCFSHAFVGLSKITTWYQYGFV
. . ..: : : : .. .. . . .::: .. .::..: .: ..::.
NP_001 MWDTSSYGYGDLFSDTWNAFTDYDVI---HLKTYDSKRVCFKEAVFSL---LPRMRYGLF
280 290 300 310 320
250 260 270 280 290 300
pF1KE6 QPQGPKANILVSGNE----IRQFARFMTEKLNVSHTGVPLGEEYILVFSR-TQNRLILNE
. : :.:: . .: ::. . ..::... : :. . ...: :. : :::.
NP_001 Y-NTP----LISGCQNTGLFRAFAQHVLHRLNITQEGPKDGKIRVTILARSTEYRKILNQ
330 340 350 360 370 380
310 320 330 340 350 360
pF1KE6 AELLLAL--AQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGATV
::. :: .. :... : . .. : : .:.. :......:::: :. :::: :.:
NP_001 NELVNALKTVSTFEVQIVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAV
390 400 410 420 430 440
370 380 390 400 410
pF1KE6 VELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWR---NMMPENTVTHP---ERPWDQGGIT
::. : . : :: : :. .:..:: ...:.. :: :.: .
NP_001 FELY----NCEDERCYLDLARLRGV--HYITWRRQNKVFPQDKGHHPTLGEHP--KFTNY
450 460 470 480 490
420 430 440 450 460 470
pF1KE6 HLDRAE-QARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQ
.: : . .::. . :. ..:.: :. .:
NP_001 SFDVEEFMYLVLQAAD---HVL-QHPKWPFKKKHDEL
500 510 520
480 490 500 510 520 530
pF1KE6 KWTVGLYPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTY
>>XP_016861694 (OMIM: 614789,615297) PREDICTED: EGF doma (527 aa)
initn: 133 init1: 77 opt: 259 Z-score: 319.9 bits: 69.0 E(85289): 4.4e-11
Smith-Waterman score: 259; 26.9% identity (57.7% similar) in 305 aa overlap (163-449:245-525)
140 150 160 170 180 190
pF1KE6 VELPAAALRFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPLFYTLRQFPGLAHEARLF
:..: : : .. :. : . ... .. .
XP_016 TQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCD-FINLYITQHVNNSFSTDVYIV
220 230 240 250 260 270
200 210 220 230 240
pF1KE6 FME--GWGEGAHF-DLYKLLSPKQPLLRAQLKTL-GRLLCFSHAFVGLSKITTWYQYGFV
. . ..: : : : .. .. . . .::: .. .::..: .: ..::.
XP_016 MWDTSSYGYGDLFSDTWNAFTDYDVI---HLKTYDSKRVCFKEAVFSL---LPRMRYGLF
280 290 300 310 320
250 260 270 280 290 300
pF1KE6 QPQGPKANILVSGNE----IRQFARFMTEKLNVSHTGVPLGEEYILVFSR-TQNRLILNE
. : :.:: . .: ::. . ..::... : :. . ...: :. : :::.
XP_016 Y-NTP----LISGCQNTGLFRAFAQHVLHRLNITQEGPKDGKIRVTILARSTEYRKILNQ
330 340 350 360 370 380
310 320 330 340 350 360
pF1KE6 AELLLAL--AQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGATV
::. :: .. :... : . .. : : .:.. :......:::: :. :::: :.:
XP_016 NELVNALKTVSTFEVQIVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAV
390 400 410 420 430 440
370 380 390 400 410
pF1KE6 VELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWR---NMMPENTVTHP---ERPWDQGGIT
::. : . : :: : :. .:..:: ...:.. :: :.: .
XP_016 FELY----NCEDERCYLDLARLRGV--HYITWRRQNKVFPQDKGHHPTLGEHP--KFTNY
450 460 470 480 490
420 430 440 450 460 470
pF1KE6 HLDRAE-QARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRKQ
.: : . .::. . :. ..:.: :. .:
XP_016 SFDVEEFMYLVLQAAD---HVL-QHPKWPFKKKHDEL
500 510 520
480 490 500 510 520 530
pF1KE6 KWTVGLYPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENTY
>>XP_016861698 (OMIM: 614789,615297) PREDICTED: EGF doma (252 aa)
initn: 108 init1: 77 opt: 253 Z-score: 317.3 bits: 67.4 E(85289): 6.2e-11
Smith-Waterman score: 253; 29.3% identity (58.5% similar) in 246 aa overlap (219-449:25-250)
190 200 210 220 230 240
pF1KE6 ARLFFMEGWGEGAHFDLYKLLSPKQPLLRAQLKTL-GRLLCFSHAFVGLSKITTWYQYGF
.::: .. .::..: .: ..::.
XP_016 MQSSYGYGDLFSDTWNAFTDYDVIHLKTYDSKRVCFKEAVFSL---LPRMRYGL
10 20 30 40 50
250 260 270 280 290 300
pF1KE6 VQPQGPKANILVSGNE----IRQFARFMTEKLNVSHTGVPLGEEYILVFSR-TQNRLILN
. : :.:: . .: ::. . ..::... : :. . ...: :. : :::
XP_016 FY-NTP----LISGCQNTGLFRAFAQHVLHRLNITQEGPKDGKIRVTILARSTEYRKILN
60 70 80 90 100
310 320 330 340 350 360
pF1KE6 EAELLLAL--AQEFQMKTVTVSLEDHTFADVVRLVSNASMLVSMHGAQLVTTLFLPRGAT
. ::. :: .. :... : . .. : : .:.. :......:::: :. :::: :.
XP_016 QNELVNALKTVSTFEVQIVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAA
110 120 130 140 150 160
370 380 390 400 410
pF1KE6 VVELFPYAVNPDHYTPYKTLAMLPGMDLQYVAWR---NMMPENTVTHP---ERPWDQGGI
: ::. : . : :: : : ..:..:: ...:.. :: :.: .
XP_016 VFELY----NCEDERCYLDLARLRG--VHYITWRRQNKVFPQDKGHHPTLGEHP--KFTN
170 180 190 200 210
420 430 440 450 460 470
pF1KE6 THLDRAE-QARILQSREVPRHLCCRNPEWLFRIYQDTKVDIPSLIQTIRRVVKGRPGPRK
.: : . .::. . :. ..:.: :. .:
XP_016 YSFDVEEFMYLVLQAAD---HVL-QHPKWPFKKKHDEL
220 230 240 250
480 490 500 510 520 530
pF1KE6 QKWTVGLYPGKVREARCQASVHGASEARLTVSWQIPWNLKYLKVREVKYEVWLQEQGENT
580 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:22:03 2016 done: Tue Nov 8 16:22:05 2016
Total Scan time: 8.910 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]