Result of FASTA (omim) for
pFN21AE6784
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6784, 628 aa
1>>>pF1KE6784 628 - 628 aa - 628 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4671+/-0.000383; mu= 9.6133+/- 0.024
mean_var=131.6899+/-26.518, 0's: 0 Z-trim(116.5): 30 B-trim: 182 in 1/55
Lambda= 0.111763
statistics sampled from 27657 (27687) to 27657 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.325), width: 16
Scan time: 10.250
The best scores are: opt bits E(85289)
NP_060564 (OMIM: 300418) eukaryotic peptide chain ( 628) 4166 683.5 6.1e-196
NP_002085 (OMIM: 139259) eukaryotic peptide chain ( 637) 3651 600.4 6.1e-171
NP_001123478 (OMIM: 139259) eukaryotic peptide cha ( 636) 3380 556.7 8.7e-158
NP_001123479 (OMIM: 139259) eukaryotic peptide cha ( 499) 3132 516.7 7.7e-146
NP_001138630 (OMIM: 612450) HBS1-like protein isof ( 642) 1175 201.2 9.3e-51
NP_006611 (OMIM: 612450) HBS1-like protein isoform ( 684) 1175 201.2 9.8e-51
NP_001393 (OMIM: 130590) elongation factor 1-alpha ( 462) 691 123.1 2.2e-27
XP_011533816 (OMIM: 130590) PREDICTED: elongation ( 462) 691 123.1 2.2e-27
NP_001949 (OMIM: 602959,616393,616409) elongation ( 463) 687 122.4 3.4e-27
XP_016879108 (OMIM: 602389,610678) PREDICTED: elon ( 455) 264 54.2 1.2e-06
NP_003312 (OMIM: 602389,610678) elongation factor ( 455) 264 54.2 1.2e-06
XP_011544230 (OMIM: 602389,610678) PREDICTED: elon ( 427) 242 50.7 1.3e-05
>>NP_060564 (OMIM: 300418) eukaryotic peptide chain rele (628 aa)
initn: 4166 init1: 4166 opt: 4166 Z-score: 3638.8 bits: 683.5 E(85289): 6.1e-196
Smith-Waterman score: 4166; 99.5% identity (99.5% similar) in 628 aa overlap (1-628:1-628)
10 20 30 40 50 60
pF1KE6 MDSGSSSSDSAPDCWDQVDMESTGSAPSGDGVSSAVAEAQREPLSSAFSRKLNVNAKPFV
:::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
NP_060 MDSGSSSSDSAPDCWDQVDMESPGSAPSGDGVSSAVAEAQREPLSSAFSRKLNVNAKPFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PNVHAAEFVPSFLRGPTQPPTLPAGSGSNDETCTGAGYPQGKRMGRGAPVEPSREEPLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PNVHAAEFVPSFLRGPTQPPTLPAGSGSNDETCTGAGYPQGKRMGRGAPVEPSREEPLVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LEGSNSAVTMELSEPVVENGEVEMALEESWEHSKEVSEAEPGGGSSGDSGPPEESGQEMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LEGSNSAVTMELSEPVVENGEVEMALEESWEHSKEVSEAEPGGGSSGDSGPPEESGQEMM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 EEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDKRTLEKYER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDKRTLEKYER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 EAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAPGHKSFVPNMIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAPGHKSFVPNMIG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 GASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDHTVNWSI
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_060 GASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 ERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDNL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 PNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGILSDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGILSDDT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 ETDFVAPGENLKIRLKGIEEEEILPGFILCDPSNLCHSGRTFDVQIVIIEHKSIICPGYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ETDFVAPGENLKIRLKGIEEEEILPGFILCDPSNLCHSGRTFDVQIVIIEHKSIICPGYN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 AVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDF
550 560 570 580 590 600
610 620
pF1KE6 PQMGRFTLRDEGKTIAIGKVLKLVQEKD
:::::::::::::::::::::::: :::
NP_060 PQMGRFTLRDEGKTIAIGKVLKLVPEKD
610 620
>>NP_002085 (OMIM: 139259) eukaryotic peptide chain rele (637 aa)
initn: 3511 init1: 3175 opt: 3651 Z-score: 3189.9 bits: 600.4 E(85289): 6.1e-171
Smith-Waterman score: 3651; 88.2% identity (94.1% similar) in 627 aa overlap (3-628:19-637)
10 20 30 40
pF1KE6 MDSGSSSSDSAPDCWDQVDMESTGSAPSGDGVS-SAVAEAQREP
:::::::::::::::.:::. : .: : : : .:.::::::
NP_002 MDPGSGGGGGGGGGGGSSSGSSSSDSAPDCWDQADMEAPGPGPCGGGGSLAAAAEAQREN
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 LSSAFSRKLNVNAKPFVPNVHAAEFVPSFLRGPTQPPTLPAGSGSNDETCTGAGYPQGKR
::.::::.:::::::::::::::::::::::::. :: :::...:.. ::: :
NP_002 LSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRGPAAPPP-PAGGAANNH---GAGSGAG--
70 80 90 100 110
110 120 130 140 150 160
pF1KE6 MGRGAPVEPSREEPLVSLEGSNSAVTMELSEPVVENGEVEMALEESWEHSKEVSEAEPGG
::.:::: :.:: . :::::::.::::::.:::::.::. ::::::..:.:::::::
NP_002 -GRAAPVESSQEEQSLC-EGSNSAVSMELSEPIVENGETEMSPEESWEHKEEISEAEPGG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE6 GSSGDSGPPEESGQEMMEEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQI
:: ::. :::::..:::::.::: : :::..: :::::::::::::::::::::::::::
NP_002 GSLGDGRPPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQI
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 MFLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHF
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_002 MYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHF
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE6 TILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKH
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE6 LIVLINKMDDHTVNWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSD
:::::::::: ::::: :::::::::::::::::::.:::::::::::::::::.:::::
NP_002 LIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSD
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE6 FCPWYTGLPFIPYLDNLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVM
::::: :::::::::::::::::.:::::::::::::::::::::::::::: :::::::
NP_002 FCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVM
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE6 MPNKHNVEVLGILSDDTETDFVAPGENLKIRLKGIEEEEILPGFILCDPSNLCHSGRTFD
::::::::::::::::.::: ::::::::::::::::::::::::::::.::::::::::
NP_002 MPNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFD
480 490 500 510 520 530
530 540 550 560 570 580
pF1KE6 VQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCI
.:::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_002 AQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCI
540 550 560 570 580 590
590 600 610 620
pF1KE6 ARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVQEKD
::::::::::::::::::::::::::::::::::::::::: :::
NP_002 ARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
600 610 620 630
>>NP_001123478 (OMIM: 139259) eukaryotic peptide chain r (636 aa)
initn: 3247 init1: 3089 opt: 3380 Z-score: 2953.8 bits: 556.7 E(85289): 8.7e-158
Smith-Waterman score: 3634; 88.0% identity (93.9% similar) in 627 aa overlap (3-628:19-636)
10 20 30 40
pF1KE6 MDSGSSSSDSAPDCWDQVDMESTGSAPSGDGVS-SAVAEAQREP
:::::::::::::::.:::. : .: : : : .:.::::::
NP_001 MDPGSGGGGGGGGGGGSSSGSSSSDSAPDCWDQADMEAPGPGPCGGGGSLAAAAEAQREN
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 LSSAFSRKLNVNAKPFVPNVHAAEFVPSFLRGPTQPPTLPAGSGSNDETCTGAGYPQGKR
::.::::.:::::::::::::::::::::::::. :: :::...:.. ::: :
NP_001 LSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRGPAAPPP-PAGGAANNH---GAGSGAG--
70 80 90 100 110
110 120 130 140 150 160
pF1KE6 MGRGAPVEPSREEPLVSLEGSNSAVTMELSEPVVENGEVEMALEESWEHSKEVSEAEPGG
::.:::: :.:: . :::::::.::::::. ::::.::. ::::::..:.:::::::
NP_001 -GRAAPVESSQEEQSLC-EGSNSAVSMELSEPI-ENGETEMSPEESWEHKEEISEAEPGG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE6 GSSGDSGPPEESGQEMMEEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQI
:: ::. :::::..:::::.::: : :::..: :::::::::::::::::::::::::::
NP_001 GSLGDGRPPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQI
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 MFLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHF
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_001 MYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHF
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE6 TILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKH
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE6 LIVLINKMDDHTVNWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSD
:::::::::: ::::: :::::::::::::::::::.:::::::::::::::::.:::::
NP_001 LIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSD
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE6 FCPWYTGLPFIPYLDNLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVM
::::: :::::::::::::::::.:::::::::::::::::::::::::::: :::::::
NP_001 FCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVM
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE6 MPNKHNVEVLGILSDDTETDFVAPGENLKIRLKGIEEEEILPGFILCDPSNLCHSGRTFD
::::::::::::::::.::: ::::::::::::::::::::::::::::.::::::::::
NP_001 MPNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFD
480 490 500 510 520 530
530 540 550 560 570 580
pF1KE6 VQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCI
.:::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 AQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCI
540 550 560 570 580 590
590 600 610 620
pF1KE6 ARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVQEKD
::::::::::::::::::::::::::::::::::::::::: :::
NP_001 ARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
600 610 620 630
>>NP_001123479 (OMIM: 139259) eukaryotic peptide chain r (499 aa)
initn: 3132 init1: 3132 opt: 3132 Z-score: 2739.2 bits: 516.7 E(85289): 7.7e-146
Smith-Waterman score: 3132; 93.4% identity (97.4% similar) in 499 aa overlap (130-628:1-499)
100 110 120 130 140 150
pF1KE6 QGKRMGRGAPVEPSREEPLVSLEGSNSAVTMELSEPVVENGEVEMALEESWEHSKEVSEA
::::::.:::::.::. ::::::..:.:::
NP_001 MELSEPIVENGETEMSPEESWEHKEEISEA
10 20 30
160 170 180 190 200 210
pF1KE6 EPGGGSSGDSGPPEESGQEMMEEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTI
:::::: ::. :::::..:::::.::: : :::..: :::::::::::::::::::::::
NP_001 EPGGGSLGDGRPPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTI
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE6 GGQIMFLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETE
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETE
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE6 RKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTA
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTA
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE6 GVKHLIVLINKMDDHTVNWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIK
:::::::::::::: ::::: :::::::::::::::::::.:::::::::::::::::.:
NP_001 GVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLK
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE6 EQSDFCPWYTGLPFIPYLDNLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQ
::::::::: :::::::::::::::::.:::::::::::::::::::::::::::: :::
NP_001 EQSDFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQ
280 290 300 310 320 330
460 470 480 490 500 510
pF1KE6 QLVMMPNKHNVEVLGILSDDTETDFVAPGENLKIRLKGIEEEEILPGFILCDPSNLCHSG
::::::::::::::::::::.::: ::::::::::::::::::::::::::::.::::::
NP_001 QLVMMPNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSG
340 350 360 370 380 390
520 530 540 550 560 570
pF1KE6 RTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQD
::::.:::::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_001 RTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQD
400 410 420 430 440 450
580 590 600 610 620
pF1KE6 QVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVQEKD
::::::::::::::::::::::::::::::::::::::::::::: :::
NP_001 QVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
460 470 480 490
>>NP_001138630 (OMIM: 612450) HBS1-like protein isoform (642 aa)
initn: 899 init1: 635 opt: 1175 Z-score: 1032.2 bits: 201.2 E(85289): 9.3e-51
Smith-Waterman score: 1179; 37.9% identity (67.9% similar) in 546 aa overlap (103-623:98-640)
80 90 100 110 120
pF1KE6 LRGPTQPPTLPAGSGSNDETCTGAGYPQGKRMGRGAPVEP--SREE----PLVS-LEGSN
....: ::. :: : : :. . :.
NP_001 FDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SAVTMELSEPVV---ENGEVEMALEESWEHSKEVSEAEPGGGSSGDSGPPE--ESGQEMM
. :: . : : :::. . ... .. .. .: ...::. ....:.
NP_001 KKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTIQASEEQS
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 EEKEEIRKS----KSVIVPSGAPK----KEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDK
..:: ... : . : :. .:.: ::::::::::. :....: : ..:
NP_001 STPAPVKKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 RTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAPGHK
::..:::.:.:. .. .. .:.:: . :::..: :..:: . ::: : .:..::::::
NP_001 RTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 SFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMD
.:.:::: ::.:::.::::..: .::::.::: :::::::..:... :: .: : .::::
NP_001 DFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMD
310 320 330 340 350 360
360 370 380 390 400
pF1KE6 DHTVNWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANI---KEQSDFCPWYT
. :::. ::..: :: :::..::. ..:. :.: :::.: :. ...:.. ::
NP_001 Q--VNWQQERFQEITGKLGHFLKQAGFK-ESDVGFIPTSGLSGENLITRSQSSELTKWYK
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE6 GLPFIPYLDNLPNFNRSIDGPIRLPIVDKYKDMGT--VVLGKLESGSIFKGQQLVMMPNK
:: .. .:.. .:::: :.:: . : .::.:. . ::.:.: : :..:. :: .
NP_001 GLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPN
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE6 HNVEVLGILSDDTETDFVAPGENLKIRLKGIEEEEILPGFILCDPSNLCHSGRTFDVQIV
.. : :: : .:..: :..... : :.. .: : :.: :. .. : ..:.
NP_001 ETCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARIL
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE6 IIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLR
:.. . : :. ..:: .: : . : :::...:..:: .: .:.:. . : ...:.
NP_001 IFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQ
550 560 570 580 590 600
590 600 610 620
pF1KE6 TAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVQEKD
: : :: .::: ..::: :: :.::: : : ..
NP_001 TQRPIALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE
610 620 630 640
>>NP_006611 (OMIM: 612450) HBS1-like protein isoform 1 [ (684 aa)
initn: 899 init1: 635 opt: 1175 Z-score: 1031.8 bits: 201.2 E(85289): 9.8e-51
Smith-Waterman score: 1179; 37.9% identity (67.9% similar) in 546 aa overlap (103-623:140-682)
80 90 100 110 120
pF1KE6 LRGPTQPPTLPAGSGSNDETCTGAGYPQGKRMGRGAPVEP--SREE----PLVS-LEGSN
....: ::. :: : : :. . :.
NP_006 FDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSG
110 120 130 140 150 160
130 140 150 160 170 180
pF1KE6 SAVTMELSEPVV---ENGEVEMALEESWEHSKEVSEAEPGGGSSGDSGPPE--ESGQEMM
. :: . : : :::. . ... .. .. .: ...::. ....:.
NP_006 KKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTIQASEEQS
170 180 190 200 210 220
190 200 210 220 230
pF1KE6 EEKEEIRKS----KSVIVPSGAPK----KEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDK
..:: ... : . : :. .:.: ::::::::::. :....: : ..:
NP_006 STPAPVKKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINK
230 240 250 260 270 280
240 250 260 270 280 290
pF1KE6 RTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAPGHK
::..:::.:.:. .. .. .:.:: . :::..: :..:: . ::: : .:..::::::
NP_006 RTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHK
290 300 310 320 330 340
300 310 320 330 340 350
pF1KE6 SFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMD
.:.:::: ::.:::.::::..: .::::.::: :::::::..:... :: .: : .::::
NP_006 DFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMD
350 360 370 380 390 400
360 370 380 390 400
pF1KE6 DHTVNWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANI---KEQSDFCPWYT
. :::. ::..: :: :::..::. ..:. :.: :::.: :. ...:.. ::
NP_006 Q--VNWQQERFQEITGKLGHFLKQAGFK-ESDVGFIPTSGLSGENLITRSQSSELTKWYK
410 420 430 440 450 460
410 420 430 440 450 460
pF1KE6 GLPFIPYLDNLPNFNRSIDGPIRLPIVDKYKDMGT--VVLGKLESGSIFKGQQLVMMPNK
:: .. .:.. .:::: :.:: . : .::.:. . ::.:.: : :..:. :: .
NP_006 GLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPN
470 480 490 500 510 520
470 480 490 500 510 520
pF1KE6 HNVEVLGILSDDTETDFVAPGENLKIRLKGIEEEEILPGFILCDPSNLCHSGRTFDVQIV
.. : :: : .:..: :..... : :.. .: : :.: :. .. : ..:.
NP_006 ETCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARIL
530 540 550 560 570 580
530 540 550 560 570 580
pF1KE6 IIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLR
:.. . : :. ..:: .: : . : :::...:..:: .: .:.:. . : ...:.
NP_006 IFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQ
590 600 610 620 630 640
590 600 610 620
pF1KE6 TAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVQEKD
: : :: .::: ..::: :: :.::: : : ..
NP_006 TQRPIALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE
650 660 670 680
>>NP_001393 (OMIM: 130590) elongation factor 1-alpha 1 [ (462 aa)
initn: 855 init1: 590 opt: 691 Z-score: 612.6 bits: 123.1 E(85289): 2.2e-27
Smith-Waterman score: 1029; 37.5% identity (66.7% similar) in 445 aa overlap (200-627:4-444)
170 180 190 200 210 220
pF1KE6 GPPEESGQEMMEEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGM
.: :.:.: :::::.:::: :.... :
NP_001 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGG
10 20 30
230 240 250 260 270 280
pF1KE6 VDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAP
.::::.::.:.:: : .. .. .:.:: . ::..: :.... ::: . . ::.:::
NP_001 IDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAP
40 50 60 70 80 90
290 300 310 320 330 340
pF1KE6 GHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLIN
::..:. ::: :.:::: :::...: ::::.:. :.:::::::.:: : :::.::: .:
NP_001 GHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVN
100 110 120 130 140 150
350 360 370 380 390 400
pF1KE6 KMDDHTVNWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWY-
:::. .: .:::: ... ..::.:..: . :.: :: .: :. : : ::.
NP_001 KMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDT-VAFVPISGWNGDNMLEPSANMPWFK
160 170 180 190 200 210
410 420 430 440 450
pF1KE6 -----------TGLPFIPYLDNLPNFNRSIDGPIRLPIVDKYK--DMGTVVLGKLESGSI
.: .. :: . .: : :.:::. : :: .::: .:..:.: .
NP_001 GWKVTRKDGNASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVL
220 230 240 250 260 270
460 470 480 490 500 510
pF1KE6 FKGQQLVMMPNKHNVEVLGILSDDTETDFVAPGENLKIRLKGIEEEEILPGFILCDPSN-
:. ... : . ..:: .. . . ::.:. . .:.. ... : . : .:
NP_001 KPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKND
280 290 300 310 320 330
520 530 540 550 560 570
pF1KE6 --LCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTR
. .: : .:..:..: . : :: :: :: ... : .:..::.: .
NP_001 PPMEAAG--FTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDG
340 350 360 370 380 390
580 590 600 610 620
pF1KE6 PRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVQEKD
:.:.:. .. :. . . .:.:.:.:.: .:::..:: .:.:.: :.: :..:
NP_001 PKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVG-VIKAVDKKAAGAG
400 410 420 430 440
NP_001 KVTKSAQKAQKAK
450 460
>>XP_011533816 (OMIM: 130590) PREDICTED: elongation fact (462 aa)
initn: 855 init1: 590 opt: 691 Z-score: 612.6 bits: 123.1 E(85289): 2.2e-27
Smith-Waterman score: 1029; 37.5% identity (66.7% similar) in 445 aa overlap (200-627:4-444)
170 180 190 200 210 220
pF1KE6 GPPEESGQEMMEEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGM
.: :.:.: :::::.:::: :.... :
XP_011 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGG
10 20 30
230 240 250 260 270 280
pF1KE6 VDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAP
.::::.::.:.:: : .. .. .:.:: . ::..: :.... ::: . . ::.:::
XP_011 IDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAP
40 50 60 70 80 90
290 300 310 320 330 340
pF1KE6 GHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLIN
::..:. ::: :.:::: :::...: ::::.:. :.:::::::.:: : :::.::: .:
XP_011 GHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVN
100 110 120 130 140 150
350 360 370 380 390 400
pF1KE6 KMDDHTVNWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWY-
:::. .: .:::: ... ..::.:..: . :.: :: .: :. : : ::.
XP_011 KMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDT-VAFVPISGWNGDNMLEPSANMPWFK
160 170 180 190 200 210
410 420 430 440 450
pF1KE6 -----------TGLPFIPYLDNLPNFNRSIDGPIRLPIVDKYK--DMGTVVLGKLESGSI
.: .. :: . .: : :.:::. : :: .::: .:..:.: .
XP_011 GWKVTRKDGNASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVL
220 230 240 250 260 270
460 470 480 490 500 510
pF1KE6 FKGQQLVMMPNKHNVEVLGILSDDTETDFVAPGENLKIRLKGIEEEEILPGFILCDPSN-
:. ... : . ..:: .. . . ::.:. . .:.. ... : . : .:
XP_011 KPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKND
280 290 300 310 320 330
520 530 540 550 560 570
pF1KE6 --LCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTR
. .: : .:..:..: . : :: :: :: ... : .:..::.: .
XP_011 PPMEAAG--FTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDG
340 350 360 370 380 390
580 590 600 610 620
pF1KE6 PRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVQEKD
:.:.:. .. :. . . .:.:.:.:.: .:::..:: .:.:.: :.: :..:
XP_011 PKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVG-VIKAVDKKAAGAG
400 410 420 430 440
XP_011 KVTKSAQKAQKAK
450 460
>>NP_001949 (OMIM: 602959,616393,616409) elongation fact (463 aa)
initn: 833 init1: 587 opt: 687 Z-score: 609.1 bits: 122.4 E(85289): 3.4e-27
Smith-Waterman score: 1012; 36.8% identity (67.3% similar) in 443 aa overlap (200-627:4-444)
170 180 190 200 210 220
pF1KE6 GPPEESGQEMMEEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGM
.: :.:.: :::::.:::: :.... :
NP_001 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGG
10 20 30
230 240 250 260 270 280
pF1KE6 VDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAP
.::::.::.:.:: : .. .. .:.:: . ::..: :.... ::: . ..::.:::
NP_001 IDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAP
40 50 60 70 80 90
290 300 310 320 330 340
pF1KE6 GHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLIN
::..:. ::: :.:::: :::...: ::::.:. :.:::::::.:: : :::.::: .:
NP_001 GHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVN
100 110 120 130 140 150
350 360 370 380 390 400
pF1KE6 KMDDHTVNWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWY-
:::. .: .::.: ... ..::.:..: . :.: :: : :. : : ::.
NP_001 KMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPAT-VPFVPISGWHGDNMLEPSPNMPWFK
160 170 180 190 200 210
410 420 430 440 450
pF1KE6 -----------TGLPFIPYLDNLPNFNRSIDGPIRLPIVDKYK--DMGTVVLGKLESGSI
.:. .. ::.. .: : :.:::. : :: .::: .:..:.: .
NP_001 GWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGIL
220 230 240 250 260 270
460 470 480 490 500 510
pF1KE6 FKGQQLVMMPNKHNVEVLGILSDDTETDFVAPGENLKIRLKGIEEEEILPGFILCDP-SN
:. ... : . ..:: .. . . ::.:. . .:.. ..: : . : :.
NP_001 RPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKSD
280 290 300 310 320 330
520 530 540 550 560 570
pF1KE6 LCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPR
. . : :..:..: . : ::. :. :: ... : .:..::.: . :.
NP_001 PPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPK
340 350 360 370 380 390
580 590 600 610 620
pF1KE6 FVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVQEKD
.:. .. :... . .:.:.:...: .:::..:: .:.:.: :.: :..:
NP_001 SLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVG-VIKNVEKKSGGAGKV
400 410 420 430 440 450
NP_001 TKSAQKAQKAGK
460
>>XP_016879108 (OMIM: 602389,610678) PREDICTED: elongati (455 aa)
initn: 430 init1: 147 opt: 264 Z-score: 240.6 bits: 54.2 E(85289): 1.2e-06
Smith-Waterman score: 388; 28.0% identity (54.0% similar) in 339 aa overlap (201-529:58-362)
180 190 200 210 220 230
pF1KE6 PPEESGQEMMEEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMV
: :::: ::::: ::.:. . : . .
XP_016 QGLLRLLKAPALPLLCRGLAVEAKKTYVRDKPHVNVGTIGHVDHGKTTLTAAITKILAEG
30 40 50 60 70 80
240 250 260 270 280 290
pF1KE6 DKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTILDAPG
..:::. .:. ::: .: :...... . : .:.. : ::
XP_016 GGAKFKKYEE---------------IDNAPEERARGITINAAHVEYSTAARHYAHTDCPG
90 100 110 120 130
300 310 320 330 340 350
pF1KE6 HKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINK
: ..: ::: :.. : .::..: : . ::::: .::. ::.:..: .::
XP_016 HADYVKNMITGTAPLDGCILVVAANDGPMP-------QTREHLLLARQIGVEHVVVYVNK
140 150 160 170 180
360 370 380 390 400
pF1KE6 MDDHTVNWSIERYE-ECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYT
: . .: : : .: :. : :.. .. : ..:. . :
XP_016 ADAVQDSEMVELVELEIRELLTEF----GYKGEET----PV--IVGSALCALEGRDP-EL
190 200 210 220 230
410 420 430 440 450 460
pF1KE6 GLPFIPYLDN-----LPNFNRSIDGPIRLPIVDKYK--DMGTVVLGKLESGSIFKGQQLV
:: . : . .: :... :. ::. :. :::: : :: : . ::..
XP_016 GLKSVQKLLDAVDTYIPVPARDLEKPFLLPVEAVYSVPGRGTVVTGTLERGILKKGDECE
240 250 260 270 280 290
470 480 490 500 510 520
pF1KE6 MMPNKHNVE--VLGILSDDTETDFVAPGENLKIRLKGIEEEEILPGFILCDPSNLCHSGR
.. ...:.. : :: . . :.:: ..:...:.. :... :... . .
XP_016 LLGHSKNIRTVVTGIEMFHKSLERAEAGDNLGALVRGLKREDLRRGLVMVKPGSI-KPHQ
300 310 320 330 340 350
530 540 550 560 570 580
pF1KE6 TFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQ
..:. :.
XP_016 KVEAQVYILSKEEGGRHKPFVSHFMPVMFSLTWDMACRIILPPEKELAMPGEDLKFNLIL
360 370 380 390 400 410
628 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:19:20 2016 done: Tue Nov 8 16:19:21 2016
Total Scan time: 10.250 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]