Result of FASTA (omim) for
pFN21AE6769
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6769, 534 aa
1>>>pF1KE6769 534 - 534 aa - 534 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3400+/-0.000454; mu= 18.0426+/- 0.028
mean_var=70.7158+/-14.019, 0's: 0 Z-trim(109.2): 86 B-trim: 0 in 0/52
Lambda= 0.152516
statistics sampled from 17295 (17381) to 17295 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.551), E-opt: 0.2 (0.204), width: 16
Scan time: 6.590
The best scores are: opt bits E(85289)
NP_009051 (OMIM: 606429) UDP-glucuronosyltransfera ( 534) 3596 801.1 0
NP_061966 (OMIM: 606428) UDP-glucuronosyltransfera ( 534) 3359 749.0 8.2e-216
NP_061951 (OMIM: 606430) UDP-glucuronosyltransfera ( 534) 3357 748.6 1.1e-215
NP_000454 (OMIM: 143500,191740,218800,237900,60181 ( 533) 2605 583.1 7.2e-166
NP_066307 (OMIM: 606434) UDP-glucuronosyltransfera ( 530) 2402 538.4 2e-152
NP_061949 (OMIM: 606433) UDP-glucuronosyltransfera ( 530) 2396 537.1 5e-152
NP_001063 (OMIM: 606431) UDP-glucuronosyltransfera ( 532) 2379 533.4 6.7e-151
NP_061950 (OMIM: 606432) UDP-glucuronosyltransfera ( 530) 2343 525.4 1.6e-148
NP_061948 (OMIM: 606435) UDP-glucuronosyltransfera ( 530) 2339 524.6 3e-148
NP_995584 (OMIM: 606431) UDP-glucuronosyltransfera ( 265) 1751 395.0 1.5e-109
NP_001068 (OMIM: 601903,612560) UDP-glucuronosyltr ( 530) 1509 341.9 2.8e-93
NP_066962 (OMIM: 600067) UDP-glucuronosyltransfera ( 528) 1493 338.4 3.2e-92
NP_001066 (OMIM: 600070) UDP-glucuronosyltransfera ( 528) 1485 336.6 1.1e-91
XP_016864074 (OMIM: 600070) PREDICTED: UDP-glucuro ( 525) 1468 332.9 1.5e-90
NP_006789 (OMIM: 604716) UDP-glucuronosyltransfera ( 527) 1466 332.5 2e-90
NP_001067 (OMIM: 600069) UDP-glucuronosyltransfera ( 530) 1466 332.5 2e-90
NP_001065 (OMIM: 600068) UDP-glucuronosyltransfera ( 529) 1428 324.1 6.5e-88
NP_001064 (OMIM: 603064) UDP-glucuronosyltransfera ( 529) 1427 323.9 7.6e-88
NP_444267 (OMIM: 606497) UDP-glucuronosyltransfera ( 529) 1412 320.6 7.5e-87
NP_079019 (OMIM: 616382) UDP-glucuronosyltransfera ( 527) 1411 320.4 8.7e-87
XP_011530549 (OMIM: 616382) PREDICTED: UDP-glucuro ( 533) 1305 297.0 9.2e-80
NP_001284545 (OMIM: 600067) UDP-glucuronosyltransf ( 392) 1301 296.1 1.3e-79
NP_001138239 (OMIM: 600070) UDP-glucuronosyltransf ( 444) 1159 264.9 3.7e-70
NP_001277020 (OMIM: 600070) UDP-glucuronosyltransf ( 280) 1153 263.4 6.4e-70
XP_005265759 (OMIM: 600068) PREDICTED: UDP-glucuro ( 280) 1148 262.3 1.4e-69
XP_011529852 (OMIM: 603064) PREDICTED: UDP-glucuro ( 445) 1125 257.4 6.7e-68
XP_016863149 (OMIM: 603064) PREDICTED: UDP-glucuro ( 280) 1117 255.5 1.6e-67
XP_016863150 (OMIM: 603064) PREDICTED: UDP-glucuro ( 280) 1117 255.5 1.6e-67
NP_001239204 (OMIM: 604716) UDP-glucuronosyltransf ( 527) 1099 251.7 4e-66
XP_011530531 (OMIM: 600068) PREDICTED: UDP-glucuro ( 450) 1010 232.1 2.8e-60
NP_001121646 (OMIM: 601291) 2-hydroxyacylsphingosi ( 541) 990 227.7 6.9e-59
NP_003351 (OMIM: 601291) 2-hydroxyacylsphingosine ( 541) 990 227.7 6.9e-59
NP_001309041 (OMIM: 601291) 2-hydroxyacylsphingosi ( 541) 990 227.7 6.9e-59
NP_001309043 (OMIM: 601291) 2-hydroxyacylsphingosi ( 541) 990 227.7 6.9e-59
NP_001309042 (OMIM: 601291) 2-hydroxyacylsphingosi ( 541) 990 227.7 6.9e-59
XP_016863792 (OMIM: 606497) PREDICTED: UDP-glucuro ( 391) 878 203.0 1.4e-51
NP_001288168 (OMIM: 604716) UDP-glucuronosyltransf ( 483) 858 198.7 3.5e-50
NP_001239203 (OMIM: 604716) UDP-glucuronosyltransf ( 693) 858 198.8 4.6e-50
NP_777574 (OMIM: 616384) UDP-glucuronosyltransfera ( 523) 841 194.9 4.9e-49
NP_689617 (OMIM: 616383) UDP-glucuronosyltransfera ( 523) 811 188.3 4.8e-47
XP_016864639 (OMIM: 616384) PREDICTED: UDP-glucuro ( 485) 809 187.9 6.1e-47
NP_001161788 (OMIM: 616384) UDP-glucuronosyltransf ( 489) 802 186.3 1.8e-46
XP_011512290 (OMIM: 616384) PREDICTED: UDP-glucuro ( 550) 801 186.2 2.3e-46
NP_001284544 (OMIM: 600067) UDP-glucuronosyltransf ( 369) 784 182.3 2.2e-45
XP_011512261 (OMIM: 616383) PREDICTED: UDP-glucuro ( 469) 777 180.8 7.8e-45
XP_005248300 (OMIM: 616383) PREDICTED: UDP-glucuro ( 469) 777 180.8 7.8e-45
XP_011512259 (OMIM: 616383) PREDICTED: UDP-glucuro ( 492) 774 180.2 1.3e-44
XP_011512260 (OMIM: 616383) PREDICTED: UDP-glucuro ( 489) 771 179.5 2e-44
XP_011512263 (OMIM: 616383) PREDICTED: UDP-glucuro ( 410) 767 178.6 3.2e-44
NP_001317648 (OMIM: 600068) UDP-glucuronosyltransf ( 369) 720 168.2 3.8e-41
>>NP_009051 (OMIM: 606429) UDP-glucuronosyltransferase 1 (534 aa)
initn: 3596 init1: 3596 opt: 3596 Z-score: 4277.3 bits: 801.1 E(85289): 0
Smith-Waterman score: 3596; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
490 500 510 520 530
>>NP_061966 (OMIM: 606428) UDP-glucuronosyltransferase 1 (534 aa)
initn: 3359 init1: 3359 opt: 3359 Z-score: 3995.5 bits: 749.0 E(85289): 8.2e-216
Smith-Waterman score: 3359; 93.3% identity (97.4% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
:: ::::::: :::::::::::::::::::::::: ::: ::::::.:::::::::::::
NP_061 MATGLQVPLPWLATGLLLLLSVQPWAESGKVLVVPIDGSHWLSMREVLRELHARGHQAVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
::::::::::::.:::::.::. ::: :::: .::.:: .:::::.::.. ::::..::.
NP_061 LTPEVNMHIKEENFFTLTTYAISWTQDEFDRHVLGHTQLYFETEHFLKKFFRSMAMLNNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
::. :: ::::::::::::::::::::::::::::::.::::::::::.::: : :::::
NP_061 SLVYHRSCVELLHNEALIRHLNATSFDVVLTDPVNLCAAVLAKYLSIPTVFFLRNIPCDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
:::::::::::::::.:::::::::::.:::::::::::::::::.::::::::::::::
NP_061 DFKGTQCPNPSSYIPRLLTTNSDHMTFMQRVKNMLYPLALSYICHAFSAPYASLASELFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
:::::::..:.:::::::::::::::::::::::::::::::: ::::::::::::::::
NP_061 REVSVVDILSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANRKPLSQEFEAYINASGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
490 500 510 520 530
>>NP_061951 (OMIM: 606430) UDP-glucuronosyltransferase 1 (534 aa)
initn: 3357 init1: 3357 opt: 3357 Z-score: 3993.1 bits: 748.6 E(85289): 1.1e-215
Smith-Waterman score: 3357; 93.4% identity (97.4% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
:: :::::::.:::::::::::::::::::::::::::: :::::::::.:::::::.::
NP_061 MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
:: ::::.::::.:::::.::. ::: ::::. ::.::.:::::::: ..:: ::::::.
NP_061 LTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
:: .:: ::::::::::::::.::::::::::: .::.:::::::::::::: : :::::
NP_061 SLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
:::::::::::::::.::::::::::::::::::::::::::.::. :::::::::::::
NP_061 DFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 REVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
490 500 510 520 530
>>NP_000454 (OMIM: 143500,191740,218800,237900,601816,60 (533 aa)
initn: 2605 init1: 2605 opt: 2605 Z-score: 3098.8 bits: 583.1 E(85289): 7.2e-166
Smith-Waterman score: 2605; 73.0% identity (88.5% similar) in 523 aa overlap (12-534:11-533)
10 20 30 40 50 60
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
:. :::: . ...::.:..:.::: :::: :...:. :::. ::
NP_000 MAVESQGGRPLVLGLLLCVLGPVVSHAGKILLIPVDGSHWLSMLGAIQQLQQRGHEIVV
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
:.:.....:.. :.:: .: ::. ... . .. .. ::.. .:.: ... ...
NP_000 LAPDASLYIRDGAFYTLKTYPVPFQREDVKESFVSLGHNVFENDSFLQRVIKTYKKIKKD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
: : : .::::. :. : .::::.:::: :. ..:.:::.:.::: . .::.:
NP_000 SAMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
.:..:::::: ::.:. :...:::::::::::::: .. ...: . .:::.::::..:
NP_000 EFEATQCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
:::.: ::.: :::::::.::: ::::::::::::.::::: . .:::::::::::::::
NP_000 REVTVQDLLSSASVWLFRSDFVKDYPRPIMPNMVFVGGINCLHQNPLSQEFEAYINASGE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
420 430 440 450 460 470
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>NP_066307 (OMIM: 606434) UDP-glucuronosyltransferase 1 (530 aa)
initn: 2386 init1: 2209 opt: 2402 Z-score: 2857.5 bits: 538.4 E(85289): 2e-152
Smith-Waterman score: 2402; 68.2% identity (83.8% similar) in 531 aa overlap (4-534:5-530)
10 20 30 40 50
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAV
: ::: : . ::: . .::.::.:::: ::: :..:: ....: :::..:
NP_066 MACTGWTSPLP-LCVCLLLTCG---FAEAGKLLVVPMDGSHWFTMRSVVEKLILRGHEVV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 VLTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNN
:. :::. .. . :. .:.. .: ...:: ..... .... . . :: :. .:.
NP_066 VVMPEVSWQLGRSLNCTVKTYSTSYTLEDLDREFKAFAHAQWKAQ-VRSIYSLLMGSYND
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 VSLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCD
. . : :.... :...:. .:::.:. :: . :: ..:::.:.:.: : : : :
NP_066 IFDLFFSNCRSLFKDKKLVEYLKESSFDAVFLDPFDNCGLIVAKYFSLPSVVFARGILCH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 LDFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELF
.:.::: : ::.:..: :: ::: .::.: .. : .:: : .:::..
NP_066 YLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLLCHRFFKNALEIASEIL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 QREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASG
: :. :: :..:.::.: :::.:::.:.::::.::::::: .:::: .::::::::::
NP_066 QTPVTEYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>NP_061949 (OMIM: 606433) UDP-glucuronosyltransferase 1 (530 aa)
initn: 2386 init1: 2213 opt: 2396 Z-score: 2850.4 bits: 537.1 E(85289): 5e-152
Smith-Waterman score: 2396; 67.5% identity (83.9% similar) in 535 aa overlap (1-534:1-530)
10 20 30 40 50
pF1KE6 MAR-GLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAV
::: : :.: : ..::: . .::.::.:::: ::: :..:. ....: :::..:
NP_061 MARTGWTSPIP-LCVSLLLTCG---FAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 VLTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNN
:. :::. .. . :. .:.. .: ...:: . .... .... . . .: .. :.
NP_061 VVMPEVSWQLGKSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQ-VRSLFSLFLSSSNG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 VSLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCD
. : :.... :...:. .:::.:. :: . :: ..:::.:.:.: : : : :
NP_061 FFNLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACGLIVAKYFSLPSVVFARGIACH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 LDFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELF
.:.::: : ::.:..: :: ::: .::.: .. : .:. :: .:::..
NP_061 YLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEIL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 QREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASG
: :.. :: :..:.::.: :::.:::.:.::::.::::::: .:::: .::::::::::
NP_061 QTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>NP_001063 (OMIM: 606431) UDP-glucuronosyltransferase 1 (532 aa)
initn: 2363 init1: 2363 opt: 2379 Z-score: 2830.1 bits: 533.4 E(85289): 6.7e-151
Smith-Waterman score: 2379; 68.2% identity (84.2% similar) in 525 aa overlap (11-534:10-532)
10 20 30 40 50 60
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
:...:...: .. . . :.:::: ::: ::::.. .. : :::. ::
NP_001 MACLLRSFQRISAGVFFL-ALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVV
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
..::::. .:: :..: : ::. :.:. .. .. : . .: .. : .
NP_001 VVPEVNLLLKESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSFLTA-PQTEYRNNMI
60 70 80 90 100 110
130 140 150 160 170
pF1KE6 SLALHRC-CVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCD
..:. : ::... . .. ..::...:::. ::..::.::..:.:...: .::.
NP_001 VIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 LDFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELF
:. .. :.: ::::. : :::::: ::: :.: : :. . . . : ::: ..
NP_001 LEHTFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 QREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASG
.:.:... : . .::::.: :::..::::.:::::::::::: . : :::::::::::::
NP_001 KRDVDIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCKKRKDLSQEFEAYINASG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>NP_061950 (OMIM: 606432) UDP-glucuronosyltransferase 1 (530 aa)
initn: 2342 init1: 2181 opt: 2343 Z-score: 2787.3 bits: 525.4 E(85289): 1.6e-148
Smith-Waterman score: 2343; 66.9% identity (82.4% similar) in 534 aa overlap (1-534:1-530)
10 20 30 40 50 60
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
:::. . : : . ::: . .:..::.:::: ::: :..:. ....: :::..::
NP_061 MARAGWTGLLPLYVCLLLTCG---FAKAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVV
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
. :::. .. . :. .:.. .: .. :: . .... . : : . .: . :..
NP_061 VMPEVSWQLGRSLNCTVKTYSTSYTLEDQDREFMVFADARW-TAPLRSAFSLLTSSSNGI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
. : :.... :...:. . ::.:. :: . :: ..:::.:.:.: : : : :
NP_061 FDLFFSNCRSLFNDRKLVEYLKESCFDAVFLDPFDACGLIVAKYFSLPSVVFARGIFCHY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
.:.::: : ::.:.:: :: ::: .:: : .. : .: : .:::..:
NP_061 LEEGAQCPAPLSYVPRLLLGFSDAMTFKERVWNHIMHLEEHLFCPYFFKNVLEIASEILQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
:.. :: :..:.::.: :::..::.:.::::.::::::: .:::. .:::::::::::
NP_061 TPVTAYDLYSHTSIWLLRTDFVLEYPKPVMPNMIFIGGINCHQGKPVPMEFEAYINASGE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
420 430 440 450 460 470
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>NP_061948 (OMIM: 606435) UDP-glucuronosyltransferase 1 (530 aa)
initn: 2339 init1: 2176 opt: 2339 Z-score: 2782.6 bits: 524.6 E(85289): 3e-148
Smith-Waterman score: 2339; 66.9% identity (82.8% similar) in 535 aa overlap (1-534:1-530)
10 20 30 40 50
pF1KE6 MAR-GLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAV
::: : :.: : . ::: . .::.::.:::: ::: :..:. ....: :::..:
NP_061 MARAGWTSPVP-LCVCLLLTCG---FAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 VLTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNN
:. :::. .... :. .:.. .: .. .: . .... .... . .: :. ..
NP_061 VVMPEVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWKAQAQ-SIFSLLMSSSSG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 VSLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCD
. : :.... :...:. .:::.:. :: . :: ..:::.:.:.: : : : :
NP_061 FLDLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDTCGLIVAKYFSLPSVVFTRGIFCH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 LDFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELF
.:.::: : ::.:. : :: ::: .:: : . : .:. . .:::..
NP_061 HLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLEDHLFCQYLFRNALEIASEIL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 QREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASG
: :.. :: :..:.::.: :::.:::.:.::::.::::::: .:::: .::::::::::
NP_061 QTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>NP_995584 (OMIM: 606431) UDP-glucuronosyltransferase 1 (265 aa)
initn: 1751 init1: 1751 opt: 1751 Z-score: 2087.7 bits: 395.0 E(85289): 1.5e-109
Smith-Waterman score: 1751; 98.5% identity (98.9% similar) in 265 aa overlap (270-534:1-265)
240 250 260 270 280 290
pF1KE6 QREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASG
:::::::::::: . : :::::::::::::
NP_995 MPNMVFIGGINCKKRKDLSQEFEAYINASG
10 20 30
300 310 320 330 340 350
pF1KE6 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
40 50 60 70 80 90
360 370 380 390 400 410
pF1KE6 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
100 110 120 130 140 150
420 430 440 450 460 470
pF1KE6 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
160 170 180 190 200 210
480 490 500 510 520 530
pF1KE6 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
220 230 240 250 260
534 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:11:54 2016 done: Tue Nov 8 16:11:55 2016
Total Scan time: 6.590 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]